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Your search keyword '"Lai, Jung-Nien"' showing total 308 results
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308 results on '"Lai, Jung-Nien"'

1. Preoperative Prognosis Assessment of Lumbar Spinal Surgery for Low Back Pain and Sciatica Patients based on Multimodalities and Multimodal Learning

Author

Chen, Li-Chin, Lai, Jung-Nien, Lin, Hung-En, Chen, Hsien-Te, Hung, Kuo-Hsuan, and Tsao, Yu

Subjects
Computer Science - Machine Learning
Abstract

Low back pain (LBP) and sciatica may require surgical therapy when they are symptomatic of severe pain. However, there is no effective measures to evaluate the surgical outcomes in advance. This work combined elements of Eastern medicine and machine learning, and developed a preoperative assessment tool to predict the prognosis of lumbar spinal surgery in LBP and sciatica patients. Standard operative assessments, traditional Chinese medicine body constitution assessments, planned surgical approach, and vowel pronunciation recordings were collected and stored in different modalities. Our work provides insights into leveraging modality combinations, multimodals, and fusion strategies. The interpretability of models and correlations between modalities were also inspected. Based on the recruited 105 patients, we found that combining standard operative assessments, body constitution assessments, and planned surgical approach achieved the best performance in 0.81 accuracy. Our approach is effective and can be widely applied in general practice due to simplicity and effective.

Published
2023

27. Fibromyalgia and periodontitis: Bidirectional associations in population-based 15-year retrospective cohorts.

Author

Ma, Kevin Sheng‐Kai, Lai, Jung‐Nien, Veeravalli, John Jims, Chiu, Lu‐Ting, Van Dyke, Thomas E., Wei, James Cheng‐Chung, Ma, Kevin Sheng-Kai, Lai, Jung-Nien, Chiu, Lu-Ting, and Wei, James Cheng-Chung

Abstract

Background: To determine the bidirectional link between periodontitis and fibromyalgia.Methods: In this cohort study, 196,428 periodontitis patients and 196,428 propensity score-matched non-periodontitis controls were enrolled. A Cox proportional hazard model was utilized to estimate the risk of fibromyalgia and survival analysis was adopted to assess the time-dependent effect of periodontitis on fibromyalgia. Subgroup analyses stratified by age, sex, and tracking period were conducted to identify susceptible populations. A parallel and symmetrical cohort that recruited 141,439 fibromyalgia patients and 141,439 propensity score-matched non-fibromyalgia controls ascertained the inverse effect of fibromyalgia on incident periodontitis.Results: Patients with periodontitis were more likely to develop fibromyalgia than non-periodontitis controls (HR = 1.42, 95% CI = 1.39-1.44, P < 0.001), which persisted in the survival analysis (log-rank test P < 0.0001). This effect was significant in both sexes and all age subgroups, and was particularly evident in males (HR = 1.52, 95% CI = 1.48-1.56, P < 0.001) and younger periodontitis patients (HR = 1.55, 95% CI = 1.50-1.60, P < 0.001). Fibromyalgia patients who never had periodontitis presented with greater risk for periodontitis over time (HR = 1.43, 95% CI = 1.40 - 1.45, P < 0.001; log-rank test P < 0.0001).Conclusions: Patients of both sexes and all age subgroups with periodontitis presented with a greater risk of fibromyalgia. Subgroups that were the most susceptible to periodontitis-associated fibromyalgia were periodontitis patients that were males and below 30 years old. Risks of periodontitis were also greater in fibromyalgia patients who never had periodontitis. [ABSTRACT FROM AUTHOR]

Published
2022
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