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6. Supplementary Figure Legend from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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7. Supplementary Figure 8 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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8. Supplementary Figure 1 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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9. Supplementary Figure 4 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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10. Supplementary Figure 9 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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11. Supplementary Figure 6 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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12. Supplementary Figure 2 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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13. Supplementary Figure 3 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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14. Supplementary Figure 5 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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15. Supplementary Figure 7 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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16. Supplementary Table 1 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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17. Supplementary Table 3 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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18. Data from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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19. Supplementary Table 2 from Truncated DNMT3B Isoform DNMT3B7 Suppresses Growth, Induces Differentiation, and Alters DNA Methylation in Human Neuroblastoma

Author

Ostler, Kelly R., primary, Yang, Qiwei, primary, Looney, Timothy J., primary, Zhang, Li, primary, Vasanthakumar, Aparna, primary, Tian, Yufeng, primary, Kocherginsky, Masha, primary, Raimondi, Stacey L., primary, DeMaio, Jessica G., primary, Salwen, Helen R., primary, Gu, Song, primary, Chlenski, Alexandre, primary, Naranjo, Arlene, primary, Gill, Amy, primary, Peddinti, Radhika, primary, Lahn, Bruce T., primary, Cohn, Susan L., primary, and Godley, Lucy A., primary

Published
2023
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32. Genetic basis of human brain evolution

Author

Vallender, Eric J., Mekel-Bobrov, Nitzan, and Lahn, Bruce T.

Subjects
Human evolution -- Genetic aspects, Brain -- Genetic aspects, Genetic research -- Genetic aspects, Health, Psychology and mental health
Abstract

Human evolution is characterized by a rapid increase in brain size and complexity. Decades of research have made important strides in identifying anatomical and physiological substrates underlying the unique features of the human brain. By contrast, it has become possible only very recently to examine the genetic basis of human brain evolution. Through comparative genomics, tantalizing insights regarding human brain evolution have emerged. The genetic changes that potentially underlie human brain evolution span a wide range from single-nucleotide substitutions to large-scale structural alterations of the genome. Similarly, the functional consequences of these genetic changes vary greatly, including protein-sequence alterations, cis-regulatory changes and even the emergence of new genes and the extinction of existing ones. Here, we provide a general review of recent findings into the genetic basis of human brain evolution, highlight the most notable trends that have emerged and caution against over-interpretation of current data.

Published
2008

36. Accelerated evolution of nervous system genes in the origin of Homo Sapiens

Author

Dorus, Steve, Vallender, Eric J., Evans, Patrick D., Anderson, Jeffrey R., Gilbert, Sandra L., Lahn, Bruce T., Malcolm, Christine M., Wyckoff, Gerald J., and Mahowald, Michael

Subjects
Human beings -- Research, Man -- Research, Genes -- Research, Nervous system agents -- Research, Biological sciences
Abstract

The human brain size increases along with the complexities and so tests were conducted, including studies on the diverse aspects of the nervous system biology, to probe the genetic basis of the changes in the brain. These studies concluded that the phenotypic evolution of the human nervous system plays an important role in the evolution of the brain.

Published
2004

37. How mammalian sex chromosomes acquired their peculiar gene content

Author

Vallender, Eric J. and Lahn, Bruce T.

Subjects
Phenotype -- Research, Sex chromosomes -- Research, Mammals -- Genetic aspects, Mammals -- Research, Genetic research, Biological sciences
Abstract

Several evolutionary theories that may account for the nonrandom assessment of genes on the sex chromosomes are outlined. The impact of the sex chromosome gene-content on the phenotypic evolution of mammals and particularly humans is described.

Published
2004

40. Chromatin analysis of occluded genes

Author

Lee, Jae Hyun, Gaetz, Jedidiah, Bugarija, Branimir, Fernandes, Croydon J., Snyder, Gregory E., Bush, Eliot C., and Lahn, Bruce T.

Published
2009

44. The ongoing adaptive evolution of ASPM and Microcephalin is not explained by increased intelligence

Author

Mekel-Bobrov, Nitzan, Posthuma, Danielle, Gilbert, Sandra L., Lind, Penelope, Gosso, M. Florencia, Luciano, Michelle, Harris, Sarah E., Bates, Timothy C., Polderman, Tinca J.C., Whalley, Lawrence J., Fox, Helen, Starr, John M., Evans, Patrick D., Montgomery, Grant W., Fernandes, Croydon, Heutink, Peter, Martin, Nicholas G., Boomsma, Dorret I., Deary, Ian J., Wright, Margaret J., de Geus, Eco J.C., and Lahn, Bruce T.

Published
2007

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