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Your search keyword '"Lagueny, Alain"' showing total 42 results
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42 results on '"Lagueny, Alain"'

25. Levodopa-responsive dystonia

Author

Tassin, Johann, primary, Dürr, Alexandra, additional, Bonnet, Anne-Marie, additional, Gil, Roger, additional, Vidailhet, Marie, additional, Lücking, Christoph B., additional, Goas, Jean-Yves, additional, Durif, Franck, additional, Abada, Myriem, additional, Echenne, Bernard, additional, Motte, Jacques, additional, Lagueny, Alain, additional, Lacomblez, Lucette, additional, Jedynak, Pierre, additional, Bartholomé, Barbara, additional, Agid, Yves, additional, and Brice, Alexis, additional

Published
2000
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31. Letter to the editor

Author

Spaans, Frank, primary, Jennekens, Frans, additional, Brunner, Han, additional, Von Giesen, Hans Juergen, additional, Stoll, Guido, additional, Benecke, Reiner, additional, Trontelj, Jožze V., additional, St Ålberg, Erik V., additional, Lagueny, Alain, additional, De Bleecker, Jan L., additional, Engel, Andrew G., additional, Vita, Giuseppe, additional, Toscano, Antonio, additional, Beydoun, Said R., additional, Schnall, Steven, additional, Susko, Thomas, additional, Nagendran, Kulan, additional, Greenwood, Richard, additional, and Amoiridis, Georgios, additional

Published
1995
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32. Letters to the editor

Author

Amoiridis, Georgios, primary, Gutmann, Ludwig, additional, Wilkins, Dennis E., additional, Sawaya, Raja, additional, Lagueny, Alain, additional, Marthan, Roger, additional, Schuermans, Philippe, additional, Le Collen, Philippe, additional, Ferrer, Xavier, additional, Julien, Jean, additional, Kuruoglu, Reha, additional, Oh, Shin J., additional, Thompson, Brian, additional, Aggarwal, A., additional, Gutmann, L., additional, Gutierrez, A., additional, Nakazato, Okifumi, additional, Johnsen, Russel, additional, Morling, Philip, additional, and Kakulas, B. A., additional

Published
1994
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39. Polyneuropathy in Waldenström's Macroglobulinemia: Deposition of M Component on Myelin Sheaths

Author

Julien, Jean, Vital, Claude, Vallat, Jean-Michel, Lagueny, Alain, Deminiere, Colette, and Darriet, Danielle

Abstract

• A chronic sensory neuropathy was the initial symptom in a case of Waldenström's macroglobulinemia in a 53-year-old woman.Ultrastructural analysis of a biopsied peripheral nerve revealed a modification of the lamellar structure of the myelin sheath. Immunofluorescent microscopy showed IgM-positive deposits on the myelin sheath. The monoclonal globulin (M component) present in the myelin appears to be a causative factor in the neuropathy.

Published
1978
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40. [Drug induced neuropathies].

Author

Lagueny A

Subjects
Animals, Anti-Bacterial Agents adverse effects, Anti-Infective Agents administration & dosage, Anti-Retroviral Agents adverse effects, Antineoplastic Agents adverse effects, Cisplatin adverse effects, Diagnosis, Differential, Disease Models, Animal, Electromyography, Enzyme Inhibitors adverse effects, Humans, Metals, Heavy adverse effects, Occupational Diseases chemically induced, Taxoids adverse effects, Vinca Alkaloids adverse effects, Drug-Related Side Effects and Adverse Reactions, Peripheral Nervous System Diseases chemically induced
Abstract

The search for a peripheral neuropathy must be systematic when a toxic medicament for the peripheral nervous system is prescribed as well as the search for a drug induced neuropathy is part of the screening of any peripheral neuropathy, but for numerous drugs, the imputability is not strictly demonstrated. A drug induced neuropathy must be differentiated from a neuropathy related to the disease for which the drug was prescribed. It is the case in the course of some cancers and or AIDS. Moreover, the intake of a neurotoxic drug can aggravate a pre-existing neuropathy. Electrophysiological study is important to confirm the neuropathy, to specify the type, more often axonal, and the severity, and also to detect infraclinical signs of neuropathy before the beginning of the treatment. Many of these drug induced neuropathies are reproducible in animals, that is useful to try to diminish the neurotoxicity in human beings. Antineoplastic chemotherapies and antibiotics are most often implicated in drug induced neuropathies.

Published
2008

41. Peripheral nerve biopsy study in 19 cases with 17p11.2 deletion.

Author

Vital A, Vital C, Latour P, Ferrer X, Rouanet-Larivière M, Brechenmacher C, and Lagueny A

Subjects
Adolescent, Adult, Aged, Axons ultrastructure, Biopsy, Chromosomes, Human, Pair 17, Demyelinating Diseases genetics, Female, Gene Deletion, Humans, Male, Middle Aged, Myelin Sheath ultrastructure, Retrospective Studies, Axons pathology, Demyelinating Diseases pathology, Hereditary Sensory and Motor Neuropathy genetics, Hereditary Sensory and Motor Neuropathy pathology, Myelin Sheath pathology
Abstract

In most cases of hereditary neuropathy with liability to pressure palsy (HNPP) the diagnosis is now assessed by molecular detection of 17p11.2 deletion. However, the family history may be missing and the clinical presentation is not always informative. In such cases, a peripheral nerve biopsy showing the characteristic focal myelin sheath thickening ("tomaculae") may be helpful. We present a retrospective study of peripheral nerve biopsies performed in 19 patients suffering from either a mononeuropathy or a generalized sensory-motor polyneuropathy, and for whom the finding of tomaculae led to a search for 17p11.2 deletion, which was confirmed secondarily. Tomaculae and other coexisting neuropathological lesions such as uncompacted myelin, "onion bulb" formations, and axonal degeneration are described and discussed in the view of previously reported data. It appears that demyelinating lesions with tomaculae are strongly suggestive of HNPP but are not specific as they may be observed in other conditions. Moreover, these features may be overlooked if axonal degeneration is marked.

Published
2004
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42. [Amyloid neuropathies. Histopathological study of peripheral nerve biopsy in 18 cases].

Author

Bouillot S, Vital A, Favereaux A, Ferrer X, Lagueny A, and Vital C

Subjects
Adult, Aged, Amyloid analysis, Amyloidosis genetics, Bence Jones Protein urine, Biopsy, Female, Humans, Immunoglobulin Light Chains analysis, Immunoglobulin lambda-Chains analysis, Male, Middle Aged, Multiple Myeloma pathology, Mutation, Nervous System Diseases genetics, Prealbumin genetics, Retrospective Studies, Amyloidosis pathology, Nervous System Diseases pathology
Abstract

Objectives: A retrospective study of nerve and muscle biopsies since 1983, with probable amyloidosis, has been performed., Materials and Methods: Eighteen nerve and muscle biopsies, out of 29, were selected., Results: Endoneurial amyloid deposits were visible on routine sections in 11 cases, revealed by ultrastructural study in 4 cases and by Congo red and/or thioflavine stains in 3 others. Amyloid deposits were marked by anti-transthyretin (TTR) serum in 13 patients, within endoneurium in 11 cases, and only around muscle fibers in 2 others. A mutation in the TTR gene, usually Val30Met, was evidenced in 8 cases and could not be assayed in the 5 others. An immunoglobulin light chain was revealed in amyloid deposits by direct immunofluorescence in the 5 other patients, of whom 4 had multiple myeloma and the fifth a lambda light chain Bence-Jones proteinuria., Conclusion: Nerve biopsy revealed amyloidosis in 10 patients: 5 of them had a mutation in TTR gene, without any family history.

Published
2003

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