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543 results on '"Lage, Hermann"'

1. ABC-Transporters

Author: Lage, Hermann and Schwab, Manfred, editor
Published: 2017
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2. Bacteria-mediated delivery of RNAi effector molecules against viral HPV16-E7 eradicates oral squamous carcinoma cells (OSCC) via apoptosis

Author: Ahmed, Omar Bauomy and Lage, Hermann
Published: 2019
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3. Gene Therapeutic Approaches to Overcome ABCB1-Mediated Drug Resistance

Author: Lage, Hermann, -, -, Series editor, Senn, Hans-Jörg, Series editor, and Walther, Wolfgang, editor
Published: 2016
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4. Supplementary Figures S1-S2 from ABCC2 (MRP2, cMOAT) Can Be Localized in the Nuclear Membrane of Ovarian Carcinomas and Correlates with Resistance to Cisplatin and Clinical Outcome

Author: Surowiak, Pawel, primary, Materna, Verena, primary, Kaplenko, Irina, primary, Spaczynski, Marek, primary, Dolinska-Krajewska, Barbara, primary, Gebarowska, Elzbieta, primary, Dietel, Manfred, primary, Zabel, Maciej, primary, and Lage, Hermann, primary
Published: 2023
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5. Supplementary Table S1-S2 from ABCC2 (MRP2, cMOAT) Can Be Localized in the Nuclear Membrane of Ovarian Carcinomas and Correlates with Resistance to Cisplatin and Clinical Outcome

Author: Surowiak, Pawel, primary, Materna, Verena, primary, Kaplenko, Irina, primary, Spaczynski, Marek, primary, Dolinska-Krajewska, Barbara, primary, Gebarowska, Elzbieta, primary, Dietel, Manfred, primary, Zabel, Maciej, primary, and Lage, Hermann, primary
Published: 2023
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6. Supplementary Methods, Legends for Videos and Figures from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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7. Data from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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8. Supplementary Video 3 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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9. Supplementary Figure 6 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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10. Supplementary Figure 1 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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11. Supplementary Figure 4 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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12. Supplementary Video 5 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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13. Supplementary Video 2 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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14. Supplementary Table 4 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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15. Supplementary Table 2 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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16. Supplementary Video 4 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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17. Supplementary Table 1 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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18. Supplementary Figure 5 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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19. Supplementary Video 1 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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20. Supplementary Table 3 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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21. Supplementary Figure 2 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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22. Supplementary Figure 3 from Improved Cellular Pharmacokinetics and Pharmacodynamics Underlie the Wide Anticancer Activity of Sagopilone

Author: Hoffmann, Jens, primary, Vitale, Ilio, primary, Buchmann, Bernd, primary, Galluzzi, Lorenzo, primary, Schwede, Wolfgang, primary, Senovilla, Laura, primary, Skuballa, Werner, primary, Vivet, Sonia, primary, Lichtner, Rosemarie B., primary, Vicencio, José M., primary, Panaretakis, Theocharis, primary, Siemeister, Gerhard, primary, Lage, Hermann, primary, Nanty, Lisa, primary, Hammer, Stefanie, primary, Mittelstaedt, Kevin, primary, Winsel, Sebastian, primary, Eschenbrenner, Julia, primary, Castedo, Maria, primary, Demarche, Carine, primary, Klar, Ulrich, primary, and Kroemer, Guido, primary
Published: 2023
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23. Discovery of substituted 1,4-dihydroquinolines as novel class of ABCB1 modulators

Author: Hemmer, Marc, Krawczyk, Sören, Simon, Ina, Lage, Hermann, and Hilgeroth, Andreas
Published: 2015
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24. ABC-Transporters

Author: Lage, Hermann and Schwab, Manfred, editor
Published: 2011
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25. Macrocyclic diterpenes resensitizing multidrug resistant phenotypes

Author: Reis, Mariana A., Paterna, Angela, Ferreira, Ricardo J., Lage, Hermann, and Ferreira, Maria-José U.
Published: 2014
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26. Resistance to Chemotherapy in Ovarian Carcinoma

Author: Lage, Hermann, Denkert, Carsten, Schlag, P. M., editor, Senn, H. -J., editor, Kleihues, P., editor, Stiefel, F., editor, Groner, B., editor, Wallgren, A., editor, Rentchnik, P., editor, and Dietel, Manfred, editor
Published: 2007
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27. Jatrophane diterpenes and cancer multidrug resistance--ABCB1 efflux modulation and selective cell death induction

Author: Reis, Mariana Alves, Ahmed, Omar Bauomy, Spengler, Gabriella, Molnar, Joseph, Lage, Hermann, and Ferreira, Maria-Jose U.
Subjects: Oncology, Experimental, Drug resistance -- Research, Cancer -- Research, Diterpenes -- Health aspects, Biological sciences, Health, Science and technology
Abstract: ABSTRACT Background: Modulation of P-glycoprotein (ABCB1) and evaluation of the collateral sensitivity effect are among the most promising approaches to overcome multidrug resistance (MDR) in cancer. In a previous study, [...]
Published: 2016
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28. Development of small-molecule P-gp inhibitors of the N-benzyl 1,4-dihydropyridine type: Novel aspects in SAR and bioanalytical evaluation of multidrug resistance (MDR) reversal properties

Author: Baumert, Christiane, Günthel, Marianne, Krawczyk, Sören, Hemmer, Marc, Wersig, Tom, Langner, Andreas, Molnár, Joséf, Lage, Hermann, and Hilgeroth, Andreas
Published: 2013
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29. ABC-Transporters

Author: Lage, Hermann and Schwab, Manfred, editor
Published: 2009
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30. PXR and NF-κB correlate with the inducing effects of IL-1β and TNF-α on ABCG2 expression in breast cancer cell lines

Author: Malekshah, Obeid M., lage, Hermann, Bahrami, Ahmad Reza, Afshari, Jalil Tavakol, and Behravan, Javad
Published: 2012
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31. A cisplatin-resistant head and neck cancer cell line with cytoplasmic p53mut exhibits ATP-binding cassette transporter upregulation and high glutathione levels

Author: Tonigold, Manuel, Rossmann, Annette, Meinold, Marie, Bette, Michael, Märken, Melanie, Henkenius, Katharina, Bretz, Anne C., Giel, Gavin, Cai, Chengzhong, Rodepeter, Fiona R., Beneš, Vladimir, Grénman, Reidar, Carey, Thomas E., Lage, Hermann, Stiewe, Thorsten, Neubauer, Andreas, Werner, Jochen A., Brendel, Cornelia, and Mandic, Robert
Published: 2014
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32. Novel structure–activity relationships and selectivity profiling of cage dimeric 1,4-dihydropyridines as multidrug resistance (MDR) modulators

Author: Coburger, Claudius, Wollmann, Jörg, Krug, Martin, Baumert, Christiane, Seifert, Marianne, Molnár, Joséf, Lage, Hermann, and Hilgeroth, Andreas
Published: 2010
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33. Topoisomerase IIα mRNA and protein expression in ovarian carcinoma: correlation with clinicopathological factors and prognosis

Author: Faggad, Areeg, Darb-Esfahani, Silvia, Wirtz, Ralph, Sinn, Bruno, Sehouli, Jalid, Könsgen, Dominique, Lage, Hermann, Weichert, Wilko, Noske, Aurelia, Budczies, Jan, Müller, Berit M, Buckendahl, Ann-Christin, Röske, Annika, Eldin Elwali, Nasr, Dietel, Manfred, and Denkert, Carsten
Published: 2009
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34. MRP2 (ABCC2, cMOAT) expression in nuclear envelope of primary fallopian tube cancer cells is a new unfavorable prognostic factor

Author: Halon, Agnieszka, Materna, Verena, Donizy, Piotr, Matkowski, Rafal, Rabczynski, Jerzy, Lage, Hermann, and Surowiak, Pawel
Published: 2013
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35. Delivery of siRNAs to Cancer Cells via Bacteria

Author: Ahmed, Omar, primary, Krühn, Andrea, additional, and Lage, Hermann, additional
Published: 2014
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36. ABC-Transporters

Author: Lage, Hermann, primary
Published: 2014
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37. List of Contributors

Author: Adair, Jennifer E., primary, Ahmed, Jahangir, additional, Alusi, Ghassan, additional, Amit, Doron, additional, Antonia, Scott J., additional, Auci, Dominick L., additional, August, David A., additional, Balvers, Rutger K., additional, Baranyi, Lajos, additional, Beard, Brian C., additional, Brennig, Sebastian, additional, Broussard, Elizabeth K., additional, Bryson, Paul D., additional, Byrnes, Andrew P., additional, Cecil, Denise L., additional, Chan, Tim, additional, Comins, Charlie, additional, de Vries, Christiaan R., additional, DiPaola, Robert S., additional, Dirven, Clemens M.F., additional, Disis, Mary L., additional, Dropulic, Boro, additional, Embree, Heather, additional, Epperly, Michael W., additional, Fueyo, Juan, additional, Fujiwara, Toshiyoshi, additional, Fung, Hua, additional, Gabriel, Emmanuel, additional, Ganapath, Vidya, additional, Gerson, Stanton L., additional, Gill, Steven, additional, Gilon, Michal, additional, Goldufsky, Joe, additional, Gomez-Manzano, Candelaria, additional, Grandis, Jennifer Rubin, additional, Greenberger, Joel S., additional, Greiner, John W., additional, Gujrati, Maneesh, additional, Gulley, James L., additional, Hajitou, Amin, additional, Harrington, Kevin J., additional, Hatefi, Arash, additional, Heller, Loree C., additional, Heller, Richard, additional, Hemminki, Akseli, additional, Hemminki, Otto, additional, Herberman, Ronald B., additional, Herendeen, Daniel, additional, Hochberg, Abraham, additional, Hodge, James W., additional, Holt, Gregory E., additional, Huang, Ying, additional, Hyun, Insoo, additional, Jiang, Hong, additional, Kagawa, Shunsuke, additional, Karjoo, Zahra, additional, Kaufman, Howard, additional, Ke, Chien-Chih, additional, Kiem, Hans-Peter, additional, Kimmelman, Jonathan, additional, Klein, Sarah R., additional, Kuroda, Shinji, additional, Kwon, Seong Young, additional, Lachmann, Nico, additional, Lage, Hermann, additional, Lamfers, Martine L.M., additional, Lattime, Edmund C., additional, Lemoine, Nicholas R., additional, Lewis, Jonathan, additional, Liao, John B., additional, Libutti, Steven K., additional, Lin, Yuan, additional, Liu, Ren-Shyan, additional, Lu, Zheng-Rong, additional, Madan, Ravi A., additional, Matouk, Imad, additional, Melcher, Alan, additional, Miller, Andrew D., additional, Min, Jung-Joon, additional, Moritz, Thomas, additional, Mulé, James J., additional, Natsume, Atsushi, additional, Nianiaris, Nastasia, additional, Nishimura, Michael I., additional, Palena, Claudia, additional, Pandha, Hardev, additional, Pastoriza, Jessica, additional, Pinder-Schenck, Mary C., additional, Piya, Sujan, additional, Poplin, Elizabeth, additional, Puskas, John A., additional, Quinn, Thomas, additional, Rao, Ankit, additional, Reese, Jane S., additional, Relph, Kate, additional, Rojas, Juan J., additional, Saenger, Yvonne, additional, Schlom, Jeffrey, additional, Shannon, Kevin, additional, Shirley, Shawna A., additional, Simpson, Guy R., additional, Sivendran, Shanthi, additional, Slepushkin, Vladimir, additional, Songsivilai, Sirirurg, additional, Steven, Neil, additional, Thomas, Sufi Mary, additional, Thorne, Steve H., additional, Tsang, Kwong-Yok, additional, Tsujiuchi, Takashi, additional, Wakabayashi, Toshihiko, additional, Wang, Pin, additional, Wang, Xinxin, additional, Wang, Yaohe, additional, Weiss, Robert E., additional, White, Edward, additional, Yagawa, Yohsuke, additional, Yata, Teerapong, additional, Yuan, Ming, additional, and Yuan, Ziqiang, additional
Published: 2014
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38. Bacterial Delivery of RNAi Effectors

Author: Lage, Hermann, primary
Published: 2014
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39. ABCC2 (MRP2, cMOAT) Localized in the Nuclear Envelope of Breast Carcinoma Cells Correlates with Poor Clinical Outcome

Author: Maciejczyk, Adam, Jagoda, Ewa, Wysocka, Teresa, Matkowski, Rafał, Györffy, Balázs, Lage, Hermann, and Surowiak, Paweł
Published: 2012
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40. Estrogen Receptor Alpha Expression in Ovarian Cancer Predicts Longer Overall Survival

Author: Halon, Agnieszka, Materna, Verena, Drag-Zalesinska, Malgorzata, Nowak-Markwitz, Ewa, Gansukh, Tserenchunt, Donizy, Piotr, Spaczynski, Marek, Zabel, Maciej, Dietel, Manfred, Lage, Hermann, and Surowiak, Pawel
Published: 2011
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41. Estradiol, tamoxifen and ICI 182,780 alter α3 and β1 integrin expression and laminin-1 adhesion in oral squamous cell carcinoma cell cultures

Author: Nelson, Katja, Helmstaedter, Victor, Moreau, Cynthia, and Lage, Hermann
Published: 2008
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42. Impact of radiation therapy on the oncolytic adenovirus dl520: Implications on the treatment of glioblastoma

Author: Bieler, Alexa, Mantwill, Klaus, Holzmüller, Regina, Jürchott, Karsten, Kaszubiak, Alexander, Stärk, Sybille, Glockzin, Gabriel, Lage, Hermann, Grosu, Anca-Ligia, Gansbacher, Bernd, and Holm, Per Sonne
Published: 2008
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43. Interleukin-1 beta and tumor necrosis factor-alpha increase ABCG2 expression in MCF-7 breast carcinoma cell line and its mitoxantrone-resistant derivative, MCF-7/MX

Author: Mosaffa, Fatemeh, Lage, Hermann, Afshari, Jalil Tavakol, and Behravan, Javad
Published: 2009
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44. Impact of Novel MDR Modulators on Human Cancer Cells: Reversal Activities and Induction Studies

Author: Coburger, Claudius, Lage, Hermann, Molnár, Josef, and Hilgeroth, Andreas
Published: 2009
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45. Nuclear metallothionein expression correlates with cisplatin resistance of ovarian cancer cells and poor clinical outcome

Author: Surowiak, Paweł, Materna, Verena, Maciejczyk, Adam, Pudełko, Marek, Markwitz, Ewa, Spaczyński, Marek, Dietel, Manfred, Zabel, Maciej, and Lage, Hermann
Published: 2007
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46. Taxol-resistance-associated gene-3 (TRAG-3/CSAG2) expression is predictive for clinical outcome in ovarian carcinoma patients

Author: Materna, Verena, Surowiak, Paweł, Kaplenko, Irina, Spaczyński, Marek, Duan, Zhenfeng, Zabel, Maciej, Dietel, Manfred, and Lage, Hermann
Published: 2007
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47. Epoxylathyrane Derivatives as MDR-Selective Compounds for Disabling Multidrug Resistance in Cancer

Author: Reis, Mariana Alves, Matos, Ana M., Duarte, Noélia, Ahmed, Omar Bauomy, Ferreira, Ricardo J., Lage, Hermann, Ferreira, Maria-José U., Reis, Mariana Alves, Matos, Ana M., Duarte, Noélia, Ahmed, Omar Bauomy, Ferreira, Ricardo J., Lage, Hermann, and Ferreira, Maria-José U.
Abstract: Background: Multidrug resistance (MDR) has been regarded as one of the major hurdles for the successful outcome of cancer chemotherapy. The collateral sensitivity (CS) effect is one the most auspicious anti-MDR strategies. Epoxylathyrane derivatives 1-16 were obtained by derivatization of the macrocyclic diterpene epoxyboetirane A (17), a lathyrane-type macrocyclic diterpene isolated from Euphorbia boetica. Some of these compounds were found to strongly modulate P-glycoprotein (P-gp/ABCB1) efflux. Purpose: The main goal was to develop lathyrane-type macrocyclic diterpenes with improved MDR-modifying activity, by targeting more than one anti-MDR mechanism. Study design/methods: In this study, the potential CS effect of compounds 1-16 was evaluated against gastric (EPG85-257), pancreatic (EPP85-181), and colon (HT-29) human cancer cells and their drug-resistant counterparts, respectively selected against mitoxantrone (EPG85-257RNOV; EPP85-181RNOV; HT-RNOV) or daunorubicin (EPG85-257RDB; EPP85-181RDB; HT-RDB). The most promising compounds (8, 15, and 16) were investigated as apoptosis inducers, using the assays annexin V/PI and active caspase-3. Results: The compounds were more effective against the resistant gastric cell lines, being the CS effect more significant in EPG85-257RDB cells. Taking together the IC50 values and the CS effect, compounds 8, 15, and 16 exhibited the best results. Epoxyboetirane P (8), with the strongest MDR-selective antiproliferative activity against gastric carcinoma EPG85-257RDB cells (IC50 of 0.72 mu M), being 10-fold more active against this resistant subline than in sensitive gastric carcinoma cells. The CS effect elicited by compounds 15 and 16 appeared to be by inducing apoptosis via caspase-3 activation. Structure-activity relationships of the compounds were additionally obtained through regression models to clarify the structural determinants associated to the CS effect. Conclusions: This study reinforces the importance of lathyrane
Published: 2020
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48. Prediction of doxorubicin sensitivity in breast tumors based on gene expression profiles of drug-resistant cell lines correlates with patient survival

Author: Györffy, Balázs, Serra, Violeta, Jürchott, Karsten, Abdul-Ghani, Rula, Garber, Mitch, Stein, Ulrike, Petersen, Iver, Lage, Hermann, Dietel, Manfred, and Schäfer, Reinhold
Published: 2005
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49. Augmented expression of metallothionein and glutathione S-transferase pi as unfavourable prognostic factors in cisplatin-treated ovarian cancer patients

Author: Surowiak, Paweł, Materna, Verena, Kaplenko, Irina, Spaczyński, Marek, Dietel, Manfred, Lage, Hermann, and Zabel, Maciej
Published: 2005
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50. Stable and complete overcoming of MDR1/P-glycoprotein-mediated multidrug resistance in human gastric carcinoma cells by RNA interference

Author: Stege, Alexandra, Priebsch, Axel, Nieth, Christiane, and Lage, Hermann
Published: 2004
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