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5. Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19

Author

Goligher, Ewan C, Bradbury, Charlotte A, McVerry, Bryan J, Lawler, Patrick R, Berger, Jeffrey S, Gong, Michelle N, Carrier, Marc, Reynolds, Harmony R, Kumar, Anand, Turgeon, Alexis F, Kornblith, Lucy Z, Kahn, Susan R, Marshall, John C, Kim, Keri S, Houston, Brett L, Derde, Lennie PG, Cushman, Mary, Tritschler, Tobias, Angus, Derek C, Godoy, Lucas C, McQuilten, Zoe, Kirwan, Bridget-Anne, Farkouh, Michael E, Brooks, Maria M, Lewis, Roger J, Berry, Lindsay R, Lorenzi, Elizabeth, Gordon, Anthony C, Ahuja, Tania, Al-Beidh, Farah, Annane, Djillali, Arabi, Yaseen M, Aryal, Diptesh, Baumann Kreuziger, Lisa, Beane, Abi, Bhimani, Zahra, Bihari, Shailesh, Billett, Henny H, Bond, Lindsay, Bonten, Marc, Brunkhorst, Frank, Buxton, Meredith, Buzgau, Adrian, Castellucci, Lana A, Chekuri, Sweta, Chen, Jen-Ting, Cheng, Allen C, Chkhikvadze, Tamta, Coiffard, Benjamin, Contreras, Aira, Costantini, Todd W, de Brouwer, Sophie, Detry, Michelle A, Duggal, Abhijit, Džavík, Vladimír, Effron, Mark B, Eng, Heather F, Escobedo, Jorge, Estcourt, Lise J, Everett, Brendan M, Fergusson, Dean A, Fitzgerald, Mark, Fowler, Robert A, Froess, Joshua D, Fu, Zhuxuan, Galanaud, Jean P, Galen, Benjamin T, Gandotra, Sheetal, Girard, Timothy D, Goodman, Andrew L, Goossens, Herman, Green, Cameron, Greenstein, Yonatan Y, Gross, Peter L, Haniffa, Rashan, Hegde, Sheila M, Hendrickson, Carolyn M, Higgins, Alisa M, Hindenburg, Alexander A, Hope, Aluko A, Horowitz, James M, Horvat, Christopher M, Huang, David T, Hudock, Kristin, Hunt, Beverley J, Husain, Mansoor, Hyzy, Robert C, Jacobson, Jeffrey R, Jayakumar, Devachandran, Keller, Norma M, Khan, Akram, Kim, Yuri, Kindzelski, Andrei, King, Andrew J, Knudson, M Margaret, Kornblith, Aaron E, Kutcher, Matthew E, Laffan, Michael A, Lamontagne, Francois, and Le Gal, Grégoire

Subjects
Clinical Trials and Supportive Activities, Clinical Research, Comparative Effectiveness Research, Cardiovascular, Good Health and Well Being, Aged, Anticoagulants, COVID-19, Critical Illness, Female, Hemorrhage, Heparin, Hospital Mortality, Humans, Logistic Models, Male, Middle Aged, Odds Ratio, Respiration, Artificial, Thrombosis, Treatment Failure, COVID-19 Drug Treatment, REMAP-CAP Investigators, ACTIV-4a Investigators, ATTACC Investigators, Medical and Health Sciences, General & Internal Medicine
Abstract

BackgroundThrombosis and inflammation may contribute to morbidity and mortality among patients with coronavirus disease 2019 (Covid-19). We hypothesized that therapeutic-dose anticoagulation would improve outcomes in critically ill patients with Covid-19.MethodsIn an open-label, adaptive, multiplatform, randomized clinical trial, critically ill patients with severe Covid-19 were randomly assigned to a pragmatically defined regimen of either therapeutic-dose anticoagulation with heparin or pharmacologic thromboprophylaxis in accordance with local usual care. The primary outcome was organ support-free days, evaluated on an ordinal scale that combined in-hospital death (assigned a value of -1) and the number of days free of cardiovascular or respiratory organ support up to day 21 among patients who survived to hospital discharge.ResultsThe trial was stopped when the prespecified criterion for futility was met for therapeutic-dose anticoagulation. Data on the primary outcome were available for 1098 patients (534 assigned to therapeutic-dose anticoagulation and 564 assigned to usual-care thromboprophylaxis). The median value for organ support-free days was 1 (interquartile range, -1 to 16) among the patients assigned to therapeutic-dose anticoagulation and was 4 (interquartile range, -1 to 16) among the patients assigned to usual-care thromboprophylaxis (adjusted proportional odds ratio, 0.83; 95% credible interval, 0.67 to 1.03; posterior probability of futility [defined as an odds ratio

Published
2021

8. TEACHING COUNCIL OF IRELAND HISTORY REQUIREMENT

Author

BIELENBERG, ANDREW, BRADY, CIARÁN, BREATHNACH, CIARA, CABALL, MARC, CALLINAN, ELAINE, CANNY, NICHOLAS, CLEAR, CAITRIONA, CUNNINGHAM, JOHN, DONLON, REGINA, DOOLEY, TERENCE, DUFFY, SEÁN, EDWARDS, DAVID, EGAN, SIMON, ELLIS, STEVEN, FLAVIN, SUSAN, GILLESPIE, RAYMOND, HANLEY, BRIAN, HARRIS, MARY, HENNESSY, MARK, HUGHES, BRIAN, LAFFAN, MICHAEL, LANE, LEEANN, LENIHAN, PADRAIG, LYONS, MARIAN, MAC SUIBHNE, BREANDÁN, McELLIGOT, RICHARD, McMAHON, RICHARD, MARGEY, ANNALEIGH, MARLEY, LAURENCE, MILNE, IDA, MURPHY, DAVID, MURPHY, MARGARET, Ó CIOSÁIN, NIALL, Ó CRÓNÍN, DÁIBHÍ, Ó SIOCHRÚ, MICHEÁL, O’CONNOR, THOMAS, O’DONNELL, RUAN, O’NEILL, CIARÁN, OHLMEYER, JANE, STOUT, MATTHEW, TAIT, CLODAGH, WALSH, FIONNUALA, and WALSH, PATRICK

Published
2021

12. Surgical management of patients with von Willebrand disease: summary of 2 systematic reviews of the literature

Author

Brignardello-Petersen, Romina, El Alayli, Abdallah, Husainat, Nedaa, Kalot, Mohamad, Shahid, Shaneela, Aljabirii, Yazan, Britt, Alec, Alturkmani, Hani, El-Khechen, Hussein, Motaghi, Shahrzad, Roller, John, Dimassi, Ahmad, Abughanimeh, Omar, Madoukh, Bader, Arapshian, Alice, Grow, Jean M., Kouides, Peter, Laffan, Michael, Leebeek, Frank W.G., O'Brien, Sarah H., Tosetto, Alberto, James, Paula D., Connell, Nathan T., Flood, Veronica, and Mustafa, Reem A.

Published
2022
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13. Long‐term safety and efficacy outcomes of valoctocogene roxaparvovec gene transfer up to 6 years post‐treatment

Author

Symington, Emily, primary, Rangarajan, Savita, additional, Lester, Will, additional, Madan, Bella, additional, Pierce, Glenn F., additional, Raheja, Priyanka, additional, Robinson, Tara M., additional, Osmond, Dane, additional, Russell, Chris B., additional, Vettermann, Christian, additional, Agarwal, Suresh K., additional, Li, Mingjin, additional, Wong, Wing Yen, additional, and Laffan, Michael, additional

Published
2024
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18. ASH ISTH NHF WFH 2021 guidelines on the management of von Willebrand disease

Author

Connell, Nathan T., Flood, Veronica H., Brignardello-Petersen, Romina, Abdul-Kadir, Rezan, Arapshian, Alice, Couper, Susie, Grow, Jean M., Kouides, Peter, Laffan, Michael, Lavin, Michelle, Leebeek, Frank W.G., O'Brien, Sarah H., Ozelo, Margareth C., Tosetto, Alberto, Weyand, Angela C., James, Paula D., Kalot, Mohamad A., Husainat, Nedaa, and Mustafa, Reem A.

Published
2021
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19. A Mendelian randomization of γ′ and total fibrinogen levels in relation to venous thromboembolism and ischemic stroke

Author

Maners, Jillian, Gill, Dipender, Pankratz, Nathan, Laffan, Michael A., Wolberg, Alisa S., de Maat, Moniek P.M., Ligthart, Symen, Tang, Weihong, Ward-Caviness, Cavin K., Fornage, Myriam, Debette, Stephanie, Dichgans, Martin, McKnight, Barbara, Boerwinkle, Eric, CHARGE Inflammation Working Group, INVENT Consortium, MEGASTROKE consortium of the International Stroke Genetics Consortium (ISGC), Smith, Nicholas L., Morrison, Alanna C., Dehghan, Abbas, and de Vries, Paul S.

Published
2020
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21. Islam, Humanity, and Indonesian Identity: Reflections on History

Author

Laffan, Michael

Subjects
Anthropology/archeology/folklore, Regional focus/area studies, Sociology and social work
Abstract

Islam, Humanity, and Indonesian Identity: Reflections on History. By Ahmad Syafii Maarif. Translated by George A. Fowler. Singapore: National University of Singapore Press, 2018. 288 pp. In March of 2009, [...]

Published
2020
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22. Multiple myeloma and its treatment contribute to increased platelet reactivity

Author

Mitchell, Joanne L., primary, Khan, Dalia, additional, Rana, Rekha H., additional, Kriek, Neline, additional, Unsworth, Amanda J., additional, Sage, Tanya, additional, Bye, Alexander P., additional, Laffan, Michael, additional, Shapiro, Susan, additional, Thakurta, Anjan, additional, Grech, Henri, additional, Ramasamy, Karthik, additional, and Gibbins, Jonathan M., additional

Published
2023
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23. Diagnostic high-throughput sequencing of 2396 patients with bleeding, thrombotic, and platelet disorders

Author

Downes, Kate, Megy, Karyn, Duarte, Daniel, Vries, Minka, Gebhart, Johanna, Hofer, Stefanie, Shamardina, Olga, Deevi, Sri V.V., Stephens, Jonathan, Mapeta, Rutendo, Tuna, Salih, Al Hasso, Namir, Besser, Martin W., Cooper, Nichola, Daugherty, Louise, Gleadall, Nick, Greene, Daniel, Haimel, Matthias, Martin, Howard, Papadia, Sofia, Revel-Vilk, Shoshana, Sivapalaratnam, Suthesh, Symington, Emily, Thomas, Will, Thys, Chantal, Tolios, Alexander, Penkett, Christopher J., Ouwehand, Willem H., Abbs, Stephen, Laffan, Michael A., Turro, Ernest, Simeoni, Ilenia, Mumford, Andrew D., Henskens, Yvonne M.C., Pabinger, Ingrid, Gomez, Keith, and Freson, Kathleen

Published
2019
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24. Germline mutations in the transcription factor IKZF5 cause thrombocytopenia

Author

Lentaigne, Claire, Greene, Daniel, Sivapalaratnam, Suthesh, Favier, Remi, Seyres, Denis, Thys, Chantal, Grassi, Luigi, Mangles, Sarah, Sibson, Keith, Stubbs, Matthew, Burden, Frances, Bordet, Jean-Claude, Armari-Alla, Corinne, Erber, Wendy, Farrow, Samantha, Gleadall, Nicholas, Gomez, Keith, Megy, Karyn, Papadia, Sofia, Penkett, Christopher J., Sims, Matthew C., Stefanucci, Luca, Stephens, Jonathan C., Read, Randy J., Stirrups, Kathleen E., Ouwehand, Willem H., Laffan, Michael A., Frontini, Mattia, Freson, Kathleen, and Turro, Ernest

Published
2019
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25. Safety and Efficacy of Therapeutic Anticoagulation with Subcutaneous Unfractionated Heparin in Patients with Renal Failure.

Author

Simini, Giulia, Akor, Frances, Szydlo, Richard, Laffan, Michael, and Arachchillage, Deepa R.J.

Subjects
GASTROINTESTINAL hemorrhage, PULMONARY embolism, HEPARIN, KIDNEY failure, LOW-molecular-weight heparin, TREATMENT effectiveness, ANTICOAGULANTS
Abstract

This article explores the difficulties of administering anticoagulation treatment to patients with renal failure. It presents several studies that examine the safety and effectiveness of different anticoagulation options in this patient population. One potential treatment option discussed is subcutaneous unfractionated heparin (SCUFH), which offers advantages such as no monitoring requirements and the ability to administer it in an ambulatory setting. The article concludes with a retrospective study that reports the outcomes of inpatients who received SCUFH for therapeutic anticoagulation, including bleeding episodes and survival rates. The study also acknowledges the impact of the COVID-19 pandemic on treatment approaches. Overall, the article emphasizes the challenges faced by healthcare providers in managing patients with renal impairment and calls for further research to optimize anticoagulant strategies in this population. [Extracted from the article]

Published
2024
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26. The effects of pathogenic variants for inherited hemostasis disorders in 140,214 UK Biobank participants

Author

Stefanucci, Luca, primary, Collins, Janine H, additional, Sims, Matthew Christopher, additional, Barrio-Hernandez, Iñigo, additional, Sun, Luanluan, additional, Burren, Oliver, additional, Perfetto, Livia, additional, Bender, Isobel, additional, Callahan, Tiffany J, additional, Fleming, Kathryn, additional, Guerrero, Jose Antonio, additional, Hermjakob, Henning, additional, Martin, Maria J, additional, Stephenson, James David, additional, Paneerselvam, Kalpana, additional, Petrovski, Slavé, additional, Porras, Pablo, additional, Robinson, Peter N, additional, Wang, Quanli, additional, Watkins, Xavier, additional, Frontini, Mattia, additional, Laskowski, Roman A, additional, Beltrao, Pedro, additional, Di Angelantonio, Emanuele, additional, Gomez, Keith, additional, Laffan, Michael, additional, Ouwehand, Willem H, additional, Mumford, Andrew D., additional, Freson, Kathleen, additional, Carss, Keren Jacqueline, additional, Downes, Kate, additional, Gleadall, Nicholas S, additional, Megy, Karyn, additional, Bruford, Elspeth, additional, and Vuckovic, Dragana, additional

Published
2023
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29. Two-Year Outcomes of Valoctocogene Roxaparvovec Therapy for Hemophilia A

Author

Mahlangu, Johnny, Kaczmarek, Radoslaw, von Drygalski, Annette, Shapiro, Susan, Chou, Sheng-Chieh, Ozelo, Margareth C, Kenet, Gili, Peyvandi, Flora, Wang, Michael, Madan, Bella, Key, Nigel S, Laffan, Michael, Dunn, Amy L, Mason, Jane, Quon, Doris V, Symington, Emily, Leavitt, Andrew D, Oldenburg, Johannes, Chambost, Hervé, Reding, Mark T, Jayaram, Kala, Yu, Hua, Mahajan, Reena, Chavele, Konstantia-Maria, Reddy, Divya B, Henshaw, Joshua, Robinson, Tara M, Wong, Wing Yen, Pipe, Steven W, GENEr8-1 Trial Group, Hermans, Cédric, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - (SLuc) Service d'hématologie, and UCL - (SLuc) Centre de malformations vasculaires congénitales

Subjects
Male, Factor VIII, Recombinant Fusion Proteins, Gene Transfer Techniques, Humans, Hemorrhage, General Medicine, Hemophilia A, Half-Life
Abstract

BACKGROUND: Valoctocogene roxaparvovec delivers a B-domain-deleted factor VIII coding sequence with an adeno-associated virus vector to prevent bleeding in persons with severe hemophilia A. The findings of a phase 3 study of the efficacy and safety of valoctocogene roxaparvovec therapy evaluated after 52 weeks in men with severe hemophilia A have been published previously. METHODS: We conducted an open-label, single-group, multicenter, phase 3 trial in which 134 men with severe hemophilia A who were receiving factor VIII prophylaxis received a single infusion of 6×1013 vector genomes of valoctocogene roxaparvovec per kilogram of body weight. The primary end point was the change from baseline in the annualized rate of treated bleeding events at week 104 after receipt of the infusion. The pharmacokinetics of valoctocogene roxaparvovec were modeled to estimate the bleeding risk relative to the activity of transgene-derived factor VIII. RESULTS: At week 104, a total of 132 participants, including 112 with data that were prospectively collected at baseline, remained in the study. The mean annualized treated bleeding rate decreased by 84.5% from baseline (P

Published
2023

35. What is Indonesian Islam?

Author

Laffan, Michael

Subjects
Indonesia, Islam, History, Orientalism
Abstract

This paper is a preliminary essay thinking about the concept of an Indonesian Islam. After considering the impact of the ideas of Geertz and Benda in shaping the current contours of what is assumed to fit within this category, and how their notions were built on the principle that the region was far more multivocal in the past than the present, it turns to consider whether, prior to the existance of Indonesia, there was ever such a notion as Jawi Islam and questions what modern Indonesians make of their own Islamic history and its impact on the making of their religious subjectivities.

Published
2006

40. A gain-of-function variant in DIAPH1 causes dominant macrothrombocytopenia and hearing loss

Author

Stritt, Simon, Nurden, Paquita, Turro, Ernest, Greene, Daniel, Jansen, Sjoert B., Westbury, Sarah K., Petersen, Romina, Astle, William J., Marlin, Sandrine, Bariana, Tadbir K., Kostadima, Myrto, Lentaigne, Claire, Maiwald, Stephanie, Papadia, Sofia, Kelly, Anne M., Stephens, Jonathan C., Penkett, Christopher J., Ashford, Sofie, Tuna, Salih, Austin, Steve, Bakchoul, Tamam, Collins, Peter, Favier, Rémi, Lambert, Michele P., Mathias, Mary, Millar, Carolyn M., Mapeta, Rutendo, Perry, David J., Schulman, Sol, Simeoni, Ilenia, Thys, Chantal, Gomez, Keith, Erber, Wendy N., Stirrups, Kathleen, Rendon, Augusto, Bradley, John R., van Geet, Chris, Raymond, F.Lucy, Laffan, Michael A., Nurden, Alan T., Nieswandt, Bernhard, Richardson, Sylvia, Freson, Kathleen, Ouwehand, Willem H., and Mumford, Andrew D.

Published
2016
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41. A high-throughput sequencing test for diagnosing inherited bleeding, thrombotic, and platelet disorders

Author

Simeoni, Ilenia, Stephens, Jonathan C., Hu, Fengyuan, Deevi, Sri V.V., Megy, Karyn, Bariana, Tadbir K., Lentaigne, Claire, Schulman, Sol, Sivapalaratnam, Suthesh, Vries, Minka J.A., Westbury, Sarah K., Greene, Daniel, Papadia, Sofia, Alessi, Marie-Christine, Attwood, Antony P., Ballmaier, Matthias, Baynam, Gareth, Bermejo, Emilse, Bertoli, Marta, Bray, Paul F., Bury, Loredana, Cattaneo, Marco, Collins, Peter, Daugherty, Louise C., Favier, Rémi, French, Deborah L., Furie, Bruce, Gattens, Michael, Germeshausen, Manuela, Ghevaert, Cedric, Goodeve, Anne C., Guerrero, Jose A., Hampshire, Daniel J., Hart, Daniel P., Heemskerk, Johan W.M., Henskens, Yvonne M.C., Hill, Marian, Hogg, Nancy, Jolley, Jennifer D., Kahr, Walter H., Kelly, Anne M., Kerr, Ron, Kostadima, Myrto, Kunishima, Shinji, Lambert, Michele P., Liesner, Ri, López, José A., Mapeta, Rutendo P., Mathias, Mary, Millar, Carolyn M., Nathwani, Amit, Neerman-Arbez, Marguerite, Nurden, Alan T., Nurden, Paquita, Othman, Maha, Peerlinck, Kathelijne, Perry, David J., Poudel, Pawan, Reitsma, Pieter, Rondina, Matthew T., Smethurst, Peter A., Stevenson, William, Szkotak, Artur, Tuna, Salih, van Geet, Christel, Whitehorn, Deborah, Wilcox, David A., Zhang, Bin, Revel-Vilk, Shoshana, Gresele, Paolo, Bellissimo, Daniel B., Penkett, Christopher J., Laffan, Michael A., Mumford, Andrew D., Rendon, Augusto, Gomez, Keith, Freson, Kathleen, Ouwehand, Willem H., and Turro, Ernest

Published
2016
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44. Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension

Author

Hadinnapola, Charaka, Bleda, Marta, Haimel, Matthias, Screaton, Nicholas, Swift, Andrew, Dorfmüller, Peter, Preston, Stephen D., Southwood, Mark, Hernandez-Sanchez, Jules, Martin, Jennifer, Treacy, Carmen, Yates, Katherine, Bogaard, Harm, Church, Colin, Coghlan, Gerry, Condliffe, Robin, Corris, Paul A., Gibbs, Simon, Girerd, Barbara, Holden, Simon, Humbert, Marc, Kiely, David G., Lawrie, Allan, Machado, Rajiv, MacKenzie Ross, Robert, Moledina, Shahin, Montani, David, Newnham, Michael, Peacock, Andrew, Pepke-Zaba, Joanna, Rayner-Matthews, Paula, Shamardina, Olga, Soubrier, Florent, Southgate, Laura, Suntharalingam, Jay, Toshner, Mark, Trembath, Richard, Noordegraaf, Anton Vonk, Wilkins, Martin R., Wort, Stephen J., Wharton, John, Gräf, Stefan, Morrell, Nicholas W., Aitman, Timothy, Bennett, David, Caulfield, Mark, Chinnery, Patrick, Gale, Daniel, Koziell, Ania, Kuijpers, Taco W, Laffan, Michael A, Maher, Eamonn, Markus, Hugh S, Ouwehand, Willem H, Perry, David, Raymond, F Lucy, Roberts, Irene, Smith, Kenneth, Thrasher, Adrian, Watkins, Hugh, Williamson, Catherine, Woods, Geoffrey, Ashford, Sofie, Bradley, John R, Fletcher, Debra, Hammerton, Tracey, James, Roger, Kingston, Nathalie, Ouwehand, Willem H, Penkett, Christopher J, Raymond, F Lucy, Stirrups, Kathleen, Veltman, Marijke, Young, Tim, Ashford, Sofie, Brown, Matthew, Clements-Brod, Naomi, Davis, John, Dewhurst, Eleanor, Erwood, Marie, Frary, Amy, Linger, Rachel, Papadia, Sofia, Rehnstrom, Karola, Stark, Hannah, Allsup, David, Austin, Steve, Bakchoul, Tamam, Bariana, Tadbir K, Bolton-Maggs, Paula, Chalmers, Elizabeth, Collins, Peter, Erber, Wendy N, Everington, Tamara, Favier, Remi, Freson, Kathleen, Furie, Bruce, Gattens, Michael, Gomez, Keith, Greene, Daniel, Greinacher, Andreas, Hart, Daniel, Heemskerk, Johan WM, Henskens, Yvonne, Kazmi, Rashid, Keeling, David, Kelly, Anne M, Laffan, Michael A, Lambert, Michele P, Lentaigne, Claire, Liesner, Ri, Mangles, Sarah, Mathias, Mary, Millar, Carolyn M, Mumford, Andrew, Nurden, Paquita, Ouwehand, Willem H, Papadia, Sofia, Payne, Jeanette, Pasi, John, Perry, David J, Peerlinck, Kathelijne, Richards, Michael, Rondina, Matthew, Roughley, Catherine, Schulman, Sol, Schulze, Harald, Scully, Marie, Sivapalaratnam, Suthesh, Tait, R Campbell, Talks, Kate, Thachil, Jecko, Turro, Ernest, Toh, Cheng-Hock, Van Geet, Chris, De Vries, Minka, Warner, Timothy Q, Westbury, Sarah, Furnell, Abigail, Mapeta, Rutendo, Simeoni, Ilenia, Staines, Simon, Stephens, Jonathan, Stirrups, Kathleen, Whitehorn, Deborah, Watt, Christopher, Attwood, Antony, Daugherty, Louise, Deevi, Sri VV, Halmagyi, Csaba, Hu, Fengyuan, James, Roger, Matser, Vera, Meacham, Stuart, Megy, Karyn, Penkett, Christopher J, Stirrups, Kathleen, Titterton, Catherine, Tuna, Salih, Yu, Ping, von Ziegenweldt, Julie, Astle, William, Carss, Keren, Greene, Daniel, Lango-Allen, Hana, Turro, Ernest, Astle, William, Greene, Daniel, Richardson, Sylvia, Turro, Ernest, Calleja, Paul, Rankin, Stuart, Turek, Wojciech, Bryson, Christine, Anderson, Julie, Fletcher, Debra, McJannet, Coleen, Stock, Sophie, Young, Tim, Wassmer, Evangeline, Sohal, Aman, Santra, Saikat, Vogt, Julie, Chitre, Manali, Krishnakumar, Deepa, Ambegaonkar, Gautum, Maw, Anna, Armstrong, Ruth, Park, Soo-Mi, Mehta, Sarju, Paterson, Joan, Carmichael, Jenny, Allen, Louise, Hensiek, Anke, Firth, Helen, Stein, Penelope, Deegan, Patrick, Doffinger, Rainer, Parker, Alasdair, Bitner-Glindzicz, Maria, Scott, Richard, Hurst, Jane, Rosser, Elisabeth, Lees, Melissa, Clement, Emma, Henderson, Robert, Thompson, Dorothy, Gardham, Alice, Gissen, Paul, Josifova, Dragana, Thomas, Ellen, Patch, Chris, Deshpande, Charu, Flinter, Frances, Holder, Muriel, Canham, Natalie, Wakeling, Emma, Holder, Susan, Ghali, Neeti, Brady, Angie, Clowes, Virginia, MacLaren, Robert, Webster, Andrew, Moore, Anthony, Arno, Gavin, Michaelides, Michel, Rankin, Julia, Kurian, Manju, Murphy, Elaine, Carss, Keren, Sanchis-Juan, Alba, Erwood, Marie, Dewhurst, Eleanor, Grozeva, Detelina, Raymond, F Lucy, Reid, Evan, Woods, Geoff, Tischkowitz, Marc, Sandford, Richard, Ali, Sonia, Creaser-Myers, Amanda, Cookson, Victoria, DaCosta, Rosa, Dormand, Natalie, Ghataorhe, Pavandeep K, Greenhalgh, Alan, Huis in’t Veld, Anna, Kennedy, Fiona, Mackenzie Ross, Rob, Masati, Larahmie, Meehan, Sharon, Othman, Shokri, Pollock, Val, Polwarth, Gary, Rhodes, Christopher J, Rue-Albrecht, Kevin, Schotte, Gwen, Shipley, Debbie, Tan, Yvonne, Wanjiku, Ivy, Wort, John, Smith, Kenneth, Kuijpers, Taco, Thrasher, Adrian, Thaventhiran, James, Brown, Matthew, Lango Allen, Hana, Simeoni, Ilenia, Staples, Emily, Samarghitean, Crina, Alachkar, Hana, Antrobus, Richard, Arumugakani, Gururaj, Bacchelli, Chiara, Baxendale, Helen, Bethune, Claire, Bibi, Shahnaz, Booth, Claire, Browning, Michael, Burns, Siobhan, Chandra, Anita, Cooper, Nichola, Davies, Sophie, Devlin, Lisa, Doffinger, Rainer, Drewe, Elizabeth, Edgar, David, Egner, William, Ghurye, Rohit, Gilmour, Kimberley, Goddard, Sarah, Gordins, Pavel, Grigoriadou, Sofia, Hackett, Scott, Hague, Rosie, Hayman, Grant, Herwadkar, Archana, Huissoon, Aarnoud, Jolles, Stephen, Kelleher, Peter, Kumararatne, Dinakantha, Lear, Sara, Longhurst, Hilary, Lorenzo, Lorena, Maimaris, Jesmeen, Manson, Ania, McDermott, Elizabeth, Murng, Sai, Nejentsev, Sergey, Noorani, Sadia, Oksenhendler, Eric, Ponsford, Mark, Qasim, Waseem, Quinti, Isabella, Richter, Alex, Sargur, Ravishankar, Savic, Sinisa, Seneviratne, Suranjith, Sewell, Carrock, Stauss, Hans, Thomas, Moira, Welch, Steve, Willcocks, Lisa, Yeatman, Nigel, and Yong, Patrick

Published
2017
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48. Humanistic burden of problem joints for children and adults with haemophilia

Author

Burke, Tom, primary, Rodriguez‐Santana, Idaira, additional, Chowdary, Pratima, additional, Curtis, Randall, additional, Khair, Kate, additional, Laffan, Michael, additional, Mclaughlin, Paul, additional, Noone, Declan, additional, O'Mahony, Brian, additional, Pasi, John, additional, Skinner, Mark, additional, and O'Hara, Jamie, additional

Published
2022
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49. The effect of TRV027 on coagulation in COVID‐19: A pilot randomized, placebo‐controlled trial

Author

Robbins, Alexander J., primary, Che Bakri, Nur Amalina, additional, Toke‐Bjolgerud, Edward, additional, Edwards, Aaron, additional, Vikraman, Asha, additional, Michalsky, Cathy, additional, Fossler, Michael, additional, Lemm, Nana‐Marie, additional, Medhipour, Savviz, additional, Budd, William, additional, Gravani, Athanasia, additional, Hurley, Lisa, additional, Kapil, Vikas, additional, Jackson, Aimee, additional, Lonsdale, Dagan, additional, Latham, Victoria, additional, Laffan, Michael, additional, Chapman, Neil, additional, Cooper, Nichola, additional, Szydlo, Richard, additional, Boyle, Joseph, additional, Pollock, Katrina M., additional, and Owen, David, additional

Published
2022
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50. SLN140 a Small Interfering RNA Targeting Protein S Improves Hemostasis Potency in Hemophilia

Author

Prince, Raja Eladnani, primary, Schaeper, Ute, additional, Aretz, Julia, additional, Li, Bojun, additional, Reina Caro, Maria Desiré, additional, vrotniakaite-Bajerciene, Kristina, additional, Eisermann, Mona, additional, Dames, Sibylle, additional, Löffner, Kathrin, additional, Martinez, Alberto, additional, Laffan, Michael, additional, Ahnstrom, Josefin, additional, and Angelillo-Scherrer, Anne, additional

Published
2022
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