16 results on '"Ladia, Mary Ann J."'
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2. Community-based recruitment for clinical trials poses the need for social and ethical considerations
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Ladia, Mary Ann J., Sison, Olivia T., Añonuevo, Cora A., and Alejandria, Marissa M.
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- 2018
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3. Predictors of Preferred Retirement Age Among Filipino Older Employees in the Academe
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Baluscang, Jamila Dee A., primary and Ladia, Mary Ann J., additional
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- 2023
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4. Association between Body Appreciation and Depression, Anxiety, and Stress among Filipino Emerging Adults: Modification by Age and Sex at Birth.
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Regencia, Zypher Jude G., Ladia, Mary Ann J., Montoya, Jaime C., Gamalo, Margaret, Gouin, Jean-Philippe, and Baja, Emmanuel S.
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YOUNG adults , *TRANSITION to adulthood , *ANXIETY , *MENTAL imagery , *FILIPINOS - Abstract
Emerging adulthood is a new stage of development that follows identity explorations during adolescence and precedes adulthood. During this phase, varied perceptions of body image may affect the mental health status of these individuals. This research examined the association between body appreciation (BA) as a measure of body image and mental health outcomes - particularly, depression, anxiety, and stress. A cross-sectional survey was used to ascertain data from 3,127 18-29-yr-old Filipinos (67% female; mean age = 21) residing in the Philippines using an online self-administered questionnaire. BA Scale-2 (BAS-2) measured BA, whereas DASS-21 assessed levels of depression, anxiety, and stress. Associations between BA, and mental health outcomes were estimated using Poisson regression models with a log-link function and a robust variance estimator. A higher BAS-2 score (2nd-4th Quartiles) is associated with a reduced risk of severe/extreme levels of depression, anxiety, and stress than a low BAS-2 score (1st Quartile). Moreover, the association between BA and stress may be stronger among female participants (p-value interaction = 0.01) and late emerging adults (p-value interaction = 0.47). However, effect modification by age and sex was insignificant for the association between BA and anxiety and depression (p-values for interaction > 0.15). [ABSTRACT FROM AUTHOR]
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- 2024
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5. Effect of body image perception and skin-lightening practices on mental health of Filipino emerging adults: a mixed-methods approach protocol
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Regencia, Zypher Jude G, primary, Gouin, Jean-Philippe, additional, Ladia, Mary Ann J, additional, Montoya, Jaime C, additional, and Baja, Emmanuel S, additional
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- 2023
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6. Prevalence of and Associations for Complementary and Alternative Medicine Use among Apparently Healthy Individuals in the Philippine LIFECARE Cohort
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Ladia, Mary Ann J., primary, Sison, Olivia T., additional, Castillo-Carandang, Nina T., additional, Sy, Rody G., additional, Llanes, Elmer Jasper B., additional, Reganit, Paul Ferdinand M., additional, Punzalan, Felix Eduardo R., additional, Gumatay, Wilbert Allan G., additional, and Velandria, Felicidad V., additional
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- 2019
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7. High TB burden and low notification rates in the Philippines: The 2016 national TB prevalence survey.
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Lansang, Mary Ann D., Alejandria, Marissa M., Law, Irwin, Juban, Noel R., Amarillo, Maria Lourdes E., Sison, Olivia T., Cruz, Jose Rene B., Ang, Concepcion F., Buensalido, Joseph Adrian L., Cañal, Johanna Patricia A., Castillo-Carandang, Nina T., Cordero, Cynthia P., Gaviola, Donna Mae G., Ladia, Mary Ann J., Mantaring III, Jacinto Blas V., Mendoza, Myrna T., Salamat, Maria Sonia S., Lam, Hilton Y., Tadolini, Marina, and Garfin, Anna Marie Celina G.
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SPUTUM examination ,TUBERCULOSIS ,CLUSTER sampling ,PATIENT-centered care ,COUGH ,TUBERCULOSIS in cattle - Abstract
Setting: The 3
rd national tuberculosis (TB) survey in the Philippines in 2007 reported a significant decline in the prevalence of TB. Since then, more significant investments for TB control have been made, yet TB burden estimates from routine surveillance data remain relatively stable. Objective: To estimate the prevalence of bacteriologically confirmed pulmonary TB in the Philippines amongst individuals aged ≥15 years in 2016. Design: In March–December 2016, we conducted a population-based survey with stratified, multi-stage cluster sampling of residents in 106 clusters aged ≥15 years. Survey participants were screened for TB by symptom-based interview and digital chest X-ray. Those with cough ≥2 weeks and/or haemoptysis and/or chest X-ray suggestive of TB were requested to submit 2 sputum specimens for Xpert MTB/RIF, direct sputum smear microscopy using LED fluorescent microscopy, and mycobacterial solid culture (Ogawa method). Bacteriologically confirmed pulmonary TB was defined as MTB culture positive and/or Xpert positive. Results: There were 46,689 individuals interviewed, and 41,444 (88.8%) consented to a chest X-ray. There were 18,597 (39.8%) eligible for sputum examination and 16,242 (87.3%) submitted at least one specimen. Out of 16,058 sputum-eligible participants, 183 (1.1%) were smear-positive. There were 466 bacteriologically confirmed TB cases: 238 (51.1%) Xpert positive, 69 (14.8%) culture positive, and 159 (34.1%) positive by both Xpert and culture. The estimated TB prevalence per 100,000 population aged ≥15 years was 434 (95% CI: 350−518) for smear-positive TB, and 1,159 (95% CI: 1,016−1,301) for bacteriologically confirmed TB. Conclusion: This nationally representative survey found that the TB burden in the Philippines in 2016 was higher than estimated from routine TB surveillance data. There was no evidence of a decline in smear and culture positive TB from the 2007 survey despite significant investments in TB control. New strategies for case-finding and patient-centered care must be intensified and expanded. [ABSTRACT FROM AUTHOR]- Published
- 2021
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8. Clinical Ramifications of TB Stigma in Baguio City, Philippines
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Ladia, Mary Ann J., primary and Millard, Ann V., additional
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- 2017
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9. TB meets IE: contributions of ethnography
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Millard, Ann V., primary and Ladia, Mary Ann J., additional
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- 2015
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10. Keten van Liefde: Chain of Love
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Ladia, Mary Ann J.
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Keten van Liefde: Chain of Love (Book) -- Book reviews ,Books -- Book reviews ,Regional focus/area studies - Published
- 2004
11. Economic Evaluation of Oral Ivermectin, Alone or in Combination with Permethrin, versus Permethrin, in the Treatment of Classic Scabies in the Philippine Setting.
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Genuino RF, Gloria MAJ, Yacapin CPRS, Batac MCFR, Garcia FB Jr, Capule FR, Ladia MAJ, Santos MP, Yabes AM, and Cagayan MSFS
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Background and Objective: Oral ivermectin is recommended as an alternative to topical permethrin in Japanese, European, and CDC-STI guidelines for treating classic scabies. The combination of oral ivermectin and topical permethrin is also used in some settings. Partial economic evaluations conducted in India and Egypt have conflicting results, and no cost-effectiveness analysis in the Philippines has compared ivermectin-based regimens to permethrin for scabies treatment. We aimed to determine the cost-effectiveness of oral ivermectin, alone or in combination with permethrin, compared to permethrin, in the treatment of Filipino adult patients with classic scabies., Methods: We used a decision tree model to estimate the cost-effectiveness of two regimens, oral ivermectin alone or in combination with permethrin, compared with permethrin to treat adults and children aged five years and older with classic scabies in the outpatient setting from the household perspective in the Philippines. We estimated total costs and disability-adjusted life years (DALYs) over a one-month follow-up. Input parameters were obtained from secondary data, such as effect estimates for probabilities of clinical outcomes from a network meta-analysis, DALYs from the Global Burden of Disease 2019, and prevailing market cost in the Philippines (DPRI 2022 with recommended markup by DOH, and leading drugstores) as of August 2022. We computed for incremental cost-effectiveness ratio (ICER) and net monetary benefit (NMB) to determine which of the interventions are cost-effective. Univariate and probabilistic sensitivity analyses, and scenario analyses were conducted to assess the impact of parameter and structural uncertainty., Results: Ivermectin-based regimens are suggested to be likely cost-saving compared to permethrin in the Philippine outpatient setting. Base case analysis showed that oral ivermectin had higher cost-savings (change in cost, -1,039.31; change in DALYS, 0.00027), while combination oral ivermectin/permethrin had higher DALYs averted (change in cost, PhP -1,019.78; change in DALYs, 0.00045), compared to permethrin. Combination oral ivermectin/permethrin (56%) was the most cost-effective, followed by oral ivermectin (44%) compared to permethrin (0%) through probabilistic sensitivity analysis. Estimates for ivermectin were sensitive to risk of cure for ivermectin vs permethrin using 1-way deterministic sensitivity analysis. Oral ivermectin was favored over combination oral ivermectin/permethrin at all thresholds based on the cost-effectiveness acceptability curve., Conclusion: Both ivermectin-based regimens seem to be cost-saving compared to permethrin in the treatment of classic scabies in the Philippine outpatient setting. Clinicians may consider oral ivermectin, alone or in combination with permethrin as an alternative first-line or second-line treatment depending on patient preference, adverse event risk profile, availability, and economic capacity. This needs to be confirmed using primary data from Filipino patients to enhance the robustness of the findings and support evidence-based local decision-making in different settings. Less uncertainty in modelled parameters can give greater confidence in the results, which can be adopted for budget impact analysis and allow more rational resource allocation. Value of information analysis can be done to determine whether the expense of future RCTs or surveys in Filipinos to collect primary data is worth it. The cost of reducing uncertainty, if deemed worth the cost of further studies, may facilitate population-level decision-making and budget planning. Findings may further inform practice guideline development, coverage decisions, and national control program planning by providing the most cost-effective scabies intervention., Competing Interests: All authors declared no conflicts of interest., (© 2025 Acta Medica Philippina.)
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- 2025
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12. Understanding Perceptions and Experiences on Acceptability of Oral Ivermectin, Topical Permethrin, and their Combination in the Treatment of Adult Filipino Patients with Scabies: A Multiple Case Study.
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Genuino RF, Batac MCFR, Mariano AMB, Buenaflor MCE, Arevalo MVPN, Capule FR, Garcia FB Jr, Ladia MAJ, Santos MP, Yabes AM, and Cagayan MSFS
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Background and Objective: Oral ivermectin, a broad-spectrum anti-parasitic drug, alone or in combination with permethrin, may be a cheaper and more convenient alternative drug to topical permethrin alone in the treatment of classic scabies. There are no previous studies on the treatment acceptability of the three interventions among individual patients with scabies in the Philippines.The purpose of this study was to understand the experiences and perceptions on treatment acceptability for oral ivermectin, topical permethrin or combination treatment among patients with scabies using the multiple-case study approach., Methods: We conducted a qualitative multiple case study among adult Filipino patients with classic scabies who were prescribed oral ivermectin, topical permethrin or its combination at a government tertiary hospital dermatology outpatient clinic from December 2022 to September 2023. Semi-structured interviews were used as the primary source of data and analyzed together with chart reviews, Dermatology Life Quality Index (DLQI) scores, and clinical images. Interviews were transcribed, coded, and triangulated with other secondary data. A three-person research team employed a reflexive and iterative process of familiarization, coding, and thematic analysis using a modified Theoretical Framework of Acceptability (TFA) to generate case descriptions, within-case analyses, and cross-case syntheses., Results: The acceptability of scabies treatments (permethrin, ivermectin, and combination therapy) was generally positive. Permethrin, used in three patient cases, was generally perceived as effective but itch relief varied. The burden of whole-body application of permethrin was context-dependent, influenced by living arrangements and family support. Perceived affordability of permethrin was linked to socioeconomic status. Ivermectin, used by one patient case, was perceived as highly effective with no side effects. Its single dose use did not interfere with patient routine. Combination therapy was also considered effective but potential antagonistic effects and the cost of adding permethrin made it less preferred. Reluctance in taking oral pills was noted. All patients valued medical advice and deferred to their physicians for treatment decisions., Conclusion and Recommendations: All three treatment options were considered effective and safe. Patients generally preferred permethrin over oral ivermectin due to its topical nature and perceived lower side effects. However, affordability and logistical challenges, especially for large households and low-income families, were noted with permethrin. Oral ivermectin elicited hesitation due to its controversial role in COVID-19 and veterinary use. Concerns about added costs and potential antagonism in combination therapy were raised. Despite these considerations, patients ultimately relied on physicians for treatment decisions. This study underscores the importance of understanding patient perspectives, experiences, and the patient-physician relationship in choosing scabies interventions. Addressing patient concerns, providing education, and ensuring ease of use and affordability can enhance treatment acceptability and adherence for better outcomes., Competing Interests: All authors declared no conflicts of interest., (© 2024 Acta Medica Philippina.)
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- 2024
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13. Community Health Workers' Concept and Understanding of Diabetes: A Qualitative Study.
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Ladia MAJ, Sison OT, Castillo-Carandang NT, Sy RG, Punzalan FER, Llanes EJB, Reganit PFM, Velandria FV, and Gumatay WAG
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Objectives: Community health workers (CHWs) fill in the insufficiency of health professionals in low-income countries. The CHWs' roles include health education of their constituents whose health they likewise take care. This study aimed to describe the concept and understanding of diabetes among CHWs in the Philippines., Methods: Fifty female CHWs currently working in rural and urban areas participated in six focus group discussions with guidance from Kleinman's eight questions. With the written informed consent of the participants, discussions were recorded and transcribed by the Research Assistant. A multi-disciplinary team manually analyzed the data. Disagreements were discussed among them and the physicians provided clinical analyses and explanations on the results. Quotations of an important point of view were also presented. Pseudonyms were utilized to uphold anonymity., Results: CHWs were aged 32 to 72 years; older participants reside in rural areas. Majority were married, housekeepers, and high school graduates. Some CHWs and their family were suffering from diabetes or dyabetis , the disease of the rich according to them. Its causes were food and lifestyle, and believed to be hereditary. Complications lead to death. Amputation was feared the most. Diabetes is incurable. Persons with diabetes should take maintenance medicines, and seek physicians' and family's help. Together with the patient, the family must decide on its management. Balanced diet, healthy lifestyle, maintenance medicines, food supplements, and herbal plants were perceived treatments. The internist should lower blood sugar level as well as prolong life span. Proper diet and regular check-up prevent diabetes., Conclusions: CHWs' concept and understanding of diabetes reflect some of the biomedical causes, effects, treatment, and prevention of diabetes as well as its social determinants. The efficacy and safety of herbal plants in the treatment of diabetes, however, should be further studied. Training on diabetes care should be provided to address their fears of amputation, insulin injection, and complications., Competing Interests: All authors declared no conflict of interest and no competing financial interest exists., (© 2024 Acta Medica Philippina.)
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- 2024
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14. Accessibility of Soil-transmitted Helminthiasis Control Strategies in Selected Indigenous People Communities in the Philippines.
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Ladia MAJ, Belizario VY Jr, Cubarrubias DLPF, and Agustin AMDL
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Background: Indigenous peoples (IPs) remain vulnerable to soil-transmitted helminthiasis (STH) due to limited access to sanitary toilets, clean water, quality health education, and services. The World Health Organization recommends periodic mass drug administration (MDA) of anthelminthics, health education, and improvements in water, sanitation, and hygiene (WASH) as control strategies to reduce morbidities caused by STH in target populations such as school-age children (SAC).This paper complements the published results of the parasitological survey (prevalence and intensity of STH) conducted in selected Aeta and Ata-Manobo communities., Objectives: This study aimed to describe the accessibility of STH control strategies to respond to the needs of SAC in IP communities in Pampanga and Davao del Norte, the Philippines. It likewise intended to describe access of these IP communities to STH control strategies., Methods: Data on accessibility of and access to STH control strategies were collected using key informant interviews (KIIs) and focus group discussions (FGDs). Eleven officials and workers from the departments of health and education, local government units, and two IP leaders were interviewed on the existing STH burden in SAC, implementation of STH control strategies, particularly of MDA, health education campaigns, and improvements in WASH including good practices and challenges in program implementation.Three FGDs with parents, elementary school teachers of IP schools, and rural health midwives were conducted separately. Guide questions focused on accessibility of and access to STH prevention and control strategies for SAC in IP communities. Informed consent to conduct and record KIIs and FGDs were obtained from participants prior to participation.Analysis of a multi-disciplinary team was based on the accessibility framework for IPs accessing indigenous primary health care services by Davy et al. (2016)., Results: The characteristics of the STH control strategies and the target populations are interrelated factors that influence accessibility. Challenges in the availability of the MDA program, particularly, inadequate staffing, drug shortages, and delays in delivery affect accessibility of and access to the free STH control strategies. Perceived harm, adverse events, stigma, beliefs, and practices likewise affect access. Lack of information on the similarity of treatment through community- and school-based MDA programs also affected engagement of SAC.IP communities are special settings where geographic isolation, peace and order situation as well as water supply need to be considered to help ensure access to STH control strategies, high MDA coverage, and improvements in WASH leading to desired outcomes., Conclusions: Considering the context of IP communities and addressing the challenges in the accessibility of and access to STH control strategies are necessary to ensure successful implementation of an integrated approach in STH prevention and control strategies. Challenges in the accessibility of STH control strategies are inadequate staffing, poor inventory, and delays in the delivery of drugs, as well as poor sanitation and hygiene. Access of SAC is likewise affected by misconceptions on safety and efficacy of anthelminthics, including stigma and cultural practices. The similarity of the MDA programs based in school or community need to be disseminated., Competing Interests: All authors declared no conflicts of interest., (© 2024 Acta Medica Philippina.)
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- 2024
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15. Engagement and Resource Considerations in Developing and Implementing Mobile Health Technologies for COVID-19 Pandemic: Filipino Developers' Perspectives.
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Gonzales AB, Custodio RG, Lapitan MCM, and Ladia MAJ
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Objective: This paper aims to provide a better understanding of the different engagement, cost, and resource considerations in developing and implementing mHealth solutions in the Philippines during the COVID-19 pandemic., Methods: First, six participants completed a form to document the estimated costs of developing a pseudo mobile application with features to mitigate the pandemic. Second, ten key informant interviews determined the facilitators, barriers, and resource requirements in developing mHealth tools., Results: The average cost estimate to develop and roll out a mobile application with public health and epidemiology features is Php 4,018,907 (US $78,650). The analysis of the interviews resulted in 12 themes organized in three domains: 1) facilitators and barriers in developing and sustaining mHealth solutions; 2) costs of sustaining mHealth technologies; and 3) factors affecting the costs of development and maintenance of mHealth technologies., Conclusion: While differences in the cost estimates are evident, it provides a ballpark figure and the different factors that implementers need to sustain and maintain an mHealth solution. This paper hopes to inform policies and practices in engaging technology solution partners and in scaling up mHealth technologies., Competing Interests: All the authors of this publication declared no conflicts of interest., (© 2024 Acta Medica Philippina.)
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- 2024
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16. Schistosomiasis and Soil-transmitted Helminthiasis Morbidity Control in Selected Communities in Eastern Visayas, Philippines: Post-Haiyan.
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Ladia MAJ, Belizario VY Jr, Lacuna JM, Durano LP, and Alonte AI
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Objective: As part of the evaluation of control programs recommended by WHO, this study describes the local implementation of schistosomiasis (SCH) and soil-transmitted helminthiasis (STH) morbidity control as well as water, sanitation, and hygiene (WASH) interventions post calamity. It likewise determines the challenges, areas for improvement, and good practices in SCH and STH morbidity control strategies in Haiyan-stricken areas in Eastern and Western Samar, the Philippines., Methods: Twenty key informant interviews and eight focus group discussions documented the implementation of SCH and STH control strategies in Eastern Visayas. Data analysis was done manually by a multi-disciplinary team., Results: Mass drug administration (MDA) in schools and communities was conducted for morbidity control. MDA for STH for pre-school-age children was integrated into the Garantisadong Pambata program, while a schoolbased teacher-assisted approach was used for school-age children. WASH facilities, such as sanitary toilets, were constructed through the initiatives of the local government units (LGUs) and other private sectors. Partnerships with Plan International Philippines helped in the implementation of WASH through the conduct of Community-led Total Sanitation. Health advocacies helped instill behavioral change in the community. SCH surveillance was conducted annually while STH surveillance was irregularly implemented. Data on MDA coverage were validated through Rapid Coverage Assessment before final reporting. Discrepancies were observed due to typographical errors and the inclusion of teachers and transient migrants in the reports submitted. Challenges in the implementation of MDA include delays in drug delivery, lack of human resources, non-compliance of participants, and drug unpalatability. Challenges in WASH included the lack of hand washing facilities, inaccessibility to safe water, as well as non-utility of sanitary toilets. Strengthening health advocacy and education may help address these challenges., Conclusion: The involvement and partnership of various stakeholders such as LGUs, WASH, and veterinary sectors, together with the academe are needed to strengthen and enhance the implementation of SCH and STH control activities. An integrated approach may contribute to improvements in SCH and STH prevention and control of the communities in selected Haiyanstricken areas., Competing Interests: All authors declared no conflicts of interest., (© 2023 Acta Medica Philippina.)
- Published
- 2023
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