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2. Moving on: How to switch young people with chronic intestinal failure from pediatric to adult care. a position statement by italian society of gastroenterology and hepatology and nutrition (SIGENP) and italian society of artificial nutrition and metabolism (SINPE)

Author

Diamanti, Antonella, Capriati, Teresa, Lezo, Antonella, Spagnuolo, Maria Immacolata, Gandullia, Paolo, Norsa, Lorenzo, Lacitignola, Laura, Santarpia, Lidia, Guglielmi, Francesco Walter, De Francesco, Antonella, and Pironi, Loris

Published
2020
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6. Paediatric Home Artificial Nutrition in Italy: Report from 2016 Survey on Behalf of Artificial Nutrition Network of Italian Society for Gastroenterology, Hepatology and Nutrition (SIGENP)

Author

Lezo, Antonella, primary, Capriati, Teresa, additional, Spagnuolo, Maria, additional, Lacitignola, Laura, additional, Goreva, Irina, additional, Di Leo, Grazia, additional, Cecchi, Nicola, additional, Gandullia, Paolo, additional, Amarri, Sergio, additional, Forchielli, Maria, additional, Dipasquale, Valeria, additional, Parma, Barbara, additional, Gatti, Simona, additional, Ravaioli, Elisa, additional, Salvatore, Silvia, additional, Mainetti, Martina, additional, Norsa, Lorenzo, additional, Pellegrino, Maristella, additional, Fornaro, Martina, additional, Fiorito, Valentina, additional, Lanari, Marcello, additional, Giaquinto, Ester, additional, Verduci, Elvira, additional, Baldassarre, Maria, additional, and Diamanti, Antonella, additional

Published
2018
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7. Pediatric Chronic Intestinal Failure in Italy: Report from the 2016 Survey on Behalf of Italian Society for Gastroenterology, Hepatology and Nutrition (SIGENP)

Author

Diamanti, Antonella, primary, Capriati, Teresa, additional, Gandullia, Paolo, additional, Di Leo, Grazia, additional, Lezo, Antonella, additional, Lacitignola, Laura, additional, Spagnuolo, Maria, additional, Gatti, Simona, additional, D’Antiga, Lorenzo, additional, Verlato, Giovanna, additional, Roggero, Paola, additional, Amarri, Sergio, additional, Baldassarre, Maria, additional, Cirillo, Francesco, additional, Elia, Domenica, additional, Boldrini, Renata, additional, Campanozzi, Angelo, additional, Catassi, Carlo, additional, Aloi, Marina, additional, Romano, Claudio, additional, Candusso, Manila, additional, Cecchi, Nicola, additional, Bellini, Tommaso, additional, Tyndall, Elaine, additional, Fusaro, Fabio, additional, Caldaro, Tamara, additional, Alberti, Daniele, additional, Gamba, Piergiorgio, additional, Lima, Mario, additional, Bagolan, Pietro, additional, De Ville de Goyet, Jean, additional, Dall’Oglio, Luigi, additional, Spada, Marco, additional, and Grandi, Francesca, additional

Published
2017
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8. Italian pediatric nutrition survey

Author

Lezo, A., primary, Diamanti, A., additional, Capriati, T., additional, Gandullia, P., additional, Fiore, P., additional, Lacitignola, L., additional, Gatti, S., additional, Spagnuolo, M.I., additional, Cecchi, N., additional, Verlato, G., additional, Borodani, S., additional, Forchielli, L., additional, Panceri, R., additional, Brunori, E., additional, Pastore, M., additional, Amarri, S., additional, Abate, Rosaria, additional, Accorsi, Paola, additional, Aidala, Enrico, additional, Amarri, Sergio, additional, Ancora, Gina, additional, Angelotti, Luisella, additional, Annibali, Roberta, additional, Antonini Monica, Antonietta, additional, Banzato, Claudia, additional, Barbaglia, Michelangelo, additional, Bardasi, Giulia, additional, Barrani, Monica, additional, Basso, Tiziano, additional, Brach del Prever, Adalberto, additional, Belli, Fina, additional, Bellomo Anna, Rita, additional, Besenzon, Luigi, additional, Biagioni, Martina, additional, Bonaudo, Roberto, additional, Bruni, Giulia, additional, Brunori, Elena, additional, Cagnoli, Giacomo, additional, Campanozzi, Angelo, additional, Casaccia, Germana, additional, Castello, Mario, additional, Chiaro, Andrea, additional, Cimadore, Nicoletta, additional, Cioni, Maddalena, additional, Cortinovis, Francesca, additional, De Cosmi, Valentina, additional, De Giacomo, Costantino, additional, Del Vecchio, Sergio, additional, Diamanti, Antonella, additional, Di Leo, Grazia, additional, Di Scala, Carmen, additional, Famiani, Annalisa, additional, Felici, Enrico, additional, Ferraris, Silvio, additional, Fomasi, Martina, additional, Fontanella, Giovanna, additional, Frimaire, Alessia, additional, Fusco, Patrizia, additional, Galvagno, Graziana, additional, Gandullia, Paolo, additional, Gasparrini, Enrico, additional, Guanà, Riccardo, additional, Guerra, Azzurra, additional, Lanari, Marcello, additional, Lacitignola, Laura, additional, Lezo, Antonella, additional, Lizzoli, Francesca, additional, Maggiore, Giuseppe, additional, Magistà Anna, Maria, additional, Malaventura, Cristina, additional, Marmetucci, Luigi, additional, Mazzocchi, Alessandra, additional, Mazzoni, Elisa, additional, Melli, Paola, additional, Memmini, Graziano, additional, Meneghini, Anna, additional, Miglietti, Nunzia, additional, Migliore, Giuseppina, additional, Mistura, Laura, additional, Monaci, Alessandro, additional, Morganti, Alessia, additional, Nesi, Francesca, additional, Opinto, Vittoria, additional, Pace, Mariella, additional, Palamone, Gianluigi, additional, Panceri, Roberto, additional, Parisi, Giuseppe, additional, Pastore, Maria, additional, Penagini, Francesca, additional, Perrone, Michela, additional, Petitti, Patrizia, additional, Pettinari, Chiara, additional, Peverelli, Paola, additional, Pinon, Michele, additional, Russo, Carla, additional, Sala, Alessandra, additional, Salata, Michele, additional, Salmaso, Mara, additional, Sangerardi, Maria, additional, Santangelo, Barbara, additional, Savino, Francesco, additional, Scatà, Donata, additional, Siani, Paolo, additional, Spagnuolo, Maria Immacolata, additional, Sparano, Paola, additional, Stamati Filomena, Andreina, additional, Tulli, Monica, additional, Uga, Elena, additional, Urbano, Flavia, additional, Verlato, Giovanna, additional, Zoppo, Marisa, additional, and Zuin, Giovanna, additional

Published
2017
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9. Detection of Neuroblastoma Cells in Bone Marrow and Peripheral Blood by Different Techniques

Author

Corrias, Maria Valeria, primary, Faulkner, Lawrence B., additional, Pistorio, Angela, additional, Rosanda, Cristina, additional, Callea, Francesco, additional, Piccolo, Maria Serena Lo, additional, Scaruffi, Paola, additional, Marchi, Cinzia, additional, Lacitignola, Laura, additional, Occhino, Marzia, additional, Gambini, Claudio, additional, Tonini, Gian Paolo, additional, Haupt, Riccardo, additional, De Bernardi, Bruno, additional, Pistoia, Vito, additional, and Garaventa, Alberto, additional

Published
2004
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10. Pediatric chronic intestinal failure in italy: Report from the 2016 survey on behalf of Italian society for gastroenterology, hepatology and nutrition (SIGENP)

Author

Luigi Dall'Oglio, Paolo Gandullia, Fabio Fusaro, Antonella Diamanti, Antonella Lezo, Paola Roggero, Elaine Tyndall, Giovanna Verlato, Manila Candusso, Tamara Caldaro, Carlo Catassi, Daniele Alberti, Sergio Amarri, Claudio Romano, Maria Immacolata Spagnuolo, Mario Lima, Pietro Bagolan, Lorenzo D'Antiga, Nicola Cecchi, Grazia Di Leo, Domenica Elia, Francesca Grandi, Jean de Ville de Goyet, Marina Aloi, Simona Gatti, Renata Boldrini, Tommaso Bellini, Teresa Capriati, F. Cirillo, Maria Elisabetta Baldassarre, Marco Spada, Angelo Campanozzi, Piergiorgio Gamba, Laura Lacitignola, DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE, Facolta' di MEDICINA e CHIRURGIA, Da definire, AREA MIN. 06 - Scienze mediche, Diamanti, Antonella, Capriati, Teresa, Gandullia, Paolo, Dileo, Grazia, Lezo, Antonella, Lacitignola, Laura, Spagnuolo, Mariaimmacolata, Gatti, Simona, Dâ antiga, Lorenzo, Verlato, Giovanna, Roggero, Paola, Amarri, Sergio, Baldassarre, Mariaelisabetta, Cirillo, Francesco, Elia, Domenica, Boldrini, Renata, Campanozzi, Angelo, Catassi, Carlo, Aloi, Marina, Romano, Claudio, Candusso, Manila, Cecchi, Nicola, Bellini, Tommaso, Tyndall, Elaine, Fusaro, Fabio, Caldaro, Tamara, Alberti, Daniele, Gamba, Piergiorgio, Lima, Mario, Bagolan, Pietro, De Goyet, Jean De Ville, Dallâ oglio, Luigi, Spada, Marco, and Grandi, Francesca

Subjects
Male, Children, Home parenteral nutrition, Intestinal failure, Food Science, Nutrition and Dietetics, medicine.medical_specialty, Pediatrics, Adolescent, Nutritional Status, lcsh:TX341-641, Article, 03 medical and health sciences, 0302 clinical medicine, 030225 pediatrics, Internal medicine, Epidemiology, Prevalence, medicine, Humans, Child, Child, Preschool, Chronic Disease, Data Collection, Female, Incidence, Infant, Intestinal Diseases, Italy, Parenteral Nutrition, Home, Pediatric gastroenterology, Settore MED/38 - Pediatria Generale e Specialistica, business.industry, Incidence (epidemiology), Hepatology, Chronic intestinal failure, children, home parenteral nutrition, intestinal failure, Parenteral nutrition, 030211 gastroenterology & hepatology, Residence, business, lcsh:Nutrition. Foods and food supply, Developed country
Abstract

none 34 no Background: Intestinal failure (IF) is the reduction in functioning gut mass below the minimal level necessary for adequate digestion and absorption of nutrients and fluids for weight maintenance in adults or for growth in children. There is a paucity of epidemiologic data on pediatric IF. The purpose of this study was to determine the prevalence, incidence, regional distribution and underlying diagnosis of pediatric chronic IF (CIF) requiring home parenteral nutrition (HPN) in Italy. Methods: Local investigators were selected in 19 Italian centers either of reference for pediatric HPN or having pediatric gastroenterologists or surgeons on staff and already collaborating with the Italian Society for Pediatric Gastroenterology, Hepatology and Nutrition with regard to IF. Data requested in this survey for children at home on Parenteral Nutrition (PN) on 1 December 2016 included patient initials, year of birth, gender, family’s place of residence and underlying diagnosis determining IF. Results: We recorded 145 CIF patients on HPN aged ≤19 years. The overall prevalence was 14.12/million inhabitants (95% CI: 9.20–18.93); the overall incidence was 1.41/million inhabitant years (95% CI: 0.53–2.20). Conclusion: Our survey provides new epidemiological data on pediatric CIF in Italy; these data may be quantitatively useful in developing IF care strategy plans in all developed countries. open Diamanti, Antonella; Capriati, Teresa; Gandullia, Paolo; Dileo, Grazia; Lezo, Antonella; Lacitignola, Laura; Spagnuolo, Mariaimmacolata; Gatti, Simona; D’antiga, Lorenzo; Verlato, Giovanna; Roggero, Paola; Amarri, Sergio; Baldassarre, Mariaelisabetta; Cirillo, Francesco; Elia, Domenica; Boldrini, Renata; Campanozzi, Angelo; Catassi, Carlo; Aloi, Marina; Romano, Claudio; Candusso, Manila; Cecchi, Nicola; Bellini, Tommaso; Tyndall, Elaine; Fusaro, Fabio; Caldaro, Tamara; Alberti, Daniele; Gamba, Piergiorgio; Lima, Mario; Bagolan, Pietro; De Goyet, Jean De Ville; Dall’oglio, Luigi; Spada, Marco; Grandi, Francesca Diamanti, Antonella; Capriati, Teresa; Gandullia, Paolo; Dileo, Grazia; Lezo, Antonella; Lacitignola, Laura; Spagnuolo, Mariaimmacolata; Gatti, Simona; Dâ antiga, Lorenzo; Verlato, Giovanna; Roggero, Paola; Amarri, Sergio; Baldassarre, Mariaelisabetta; Cirillo, Francesco; Elia, Domenica; Boldrini, Renata; Campanozzi, Angelo; Catassi, Carlo; Aloi, Marina; Romano, Claudio; Candusso, Manila; Cecchi, Nicola; Bellini, Tommaso; Tyndall, Elaine; Fusaro, Fabio; Caldaro, Tamara; Alberti, Daniele; Gamba, Piergiorgio; Lima, Mario; Bagolan, Pietro; De Goyet, Jean De Ville; Dallâ oglio, Luigi; Spada, Marco; Grandi, Francesca

Published
2017

11. Italian pediatric nutrition survey

Author

Michelangelo Barbaglia, Luigi Marmetucci, Nicoletta Cimadore, Alessandro Monaci, P. Fiore, Sergio Amarri, Elena Brunori, Maddalena Cioni, Carla Russo, Monica Barrani, P. Gandullia, Giovanna Zuin, Giuseppe Parisi, Rita Bellomo Anna, Michele Pinon, Nunzia Miglietti, Francesca Lizzoli, Elisa Mazzoni, Giulia Bardasi, Marisa Zoppo, Giacomo Cagnoli, S. Borodani, L. Forchielli, Monica Tulli, Fina Belli, Michele Salata, Giovanna Verlato, Vittoria Opinto, Roberto Bonaudo, Luisella Angelotti, Giulia Bruni, Elena Uga, Costantino De Giacomo, Antonietta Antonini Monica, Riccardo Guanà, Flavia Urbano, Rosaria Abate, Barbara Santangelo, Chiara Pettinari, Giovanna Fontanella, Patrizia Fusco, L. Lacitignola, Adalberto Brach Del Prever, Gina Ancora, S. Amarri, Laura Lacitignola, Paola Sparano, Marcello Lanari, Stefano Gatti, Francesca Nesi, Valentina De Cosmi, Alessia Frimaire, A Lezo, Francesca Penagini, Carmen Di Scala, Giuseppina Migliore, Roberta Annibali, Grazia Di Leo, Paola Peverelli, Mara Salmaso, Antonella Lezo, Paola Melli, M. Pastore, E. Brunori, Claudia Banzato, M.I. Spagnuolo, Antonella Diamanti, G. Verlato, Angelo Campanozzi, Mariella Pace, Martina Biagioni, Graziano Memmini, Laura Mistura, Sergio Del Vecchio, Annalisa Famiani, Enrico Felici, Germana Casaccia, Graziana Galvagno, Mario Castello, R. Panceri, Paola Accorsi, Martina Fomasi, Francesca Cortinovis, Michela Perrone, Teresa Capriati, Andrea Chiaro, Silvio Ferraris, Nicola Cecchi, Maria Immacolata Spagnuolo, Patrizia Petitti, Cristina Malaventura, Maria Sangerardi, Enrico Gasparrini, Francesco Savino, Luigi Besenzon, Anna Meneghini, Azzurra Guerra, Alessandra Sala, Maria Magistã Anna, Enrico Aidala, Donata Scatã, Gianluigi Palamone, Tiziano Basso, Giuseppe Maggiore, A. Diamanti, Alessandra Mazzocchi, Alessia Morganti, Andreina Stamati Filomena, Paolo Siani, Roberto Panceri, Maria Pastore, Paolo Gandullia, Lezo, A., Diamanti, A., Capriati, T., Gandullia, P., Fiore, P., Lacitignola, L., Gatti, S., Spagnuolo, M. I., Cecchi, N., Verlato, G., Borodani, S., Forchielli, L., Panceri, R., Brunori, E., Pastore, M., Amarri, S., Abate, R., Accorsi, P., Aidala, E., Ancora, G., Angelotti, L., Annibali, R., Antonini Monica, A., Banzato, C., Barbaglia, M., Bardasi, G., Barrani, M., Basso, T., Brach del Prever, A., Belli, F., Bellomo Anna, R., Besenzon, L., Biagioni, M., Bonaudo, R., Bruni, G., Cagnoli, G., Campanozzi, A., Casaccia, G., Castello, M., Chiaro, A., Cimadore, N., Cioni, M., Cortinovis, F., De Cosmi, V., De Giacomo, C., Del Vecchio, S., Di Leo, G., Di Scala, C., Famiani, A., Felici, E., Ferraris, S., Fomasi, M., Fontanella, G., Frimaire, A., Fusco, P., Galvagno, G., Gasparrini, E., Guana, R., Guerra, A., Lanari, M., Lizzoli, F., Maggiore, G., Magista Anna, M., Malaventura, C., Marmetucci, L., Mazzocchi, A., Mazzoni, E., Melli, P., Memmini, G., Meneghini, A., Miglietti, N., Migliore, G., Mistura, L., Monaci, A., Morganti, A., Nesi, F., Opinto, V., Pace, M., Palamone, G., Parisi, G., Penagini, F., Perrone, M., Petitti, P., Pettinari, C., Peverelli, P., Pinon, M., Russo, C., Sala, A., Salata, M., Salmaso, M., Sangerardi, M., Santangelo, B., Savino, F., Scata, D., Siani, P., Sparano, P., Stamati Filomena, A., Tulli, M., Uga, E., Urbano, F., Zoppo, M., Zuin, G., Abate, Rosaria, Accorsi, Paola, Aidala, Enrico, Amarri, Sergio, Ancora, Gina, Angelotti, Luisella, Annibali, Roberta, Antonini Monica, Antonietta, Banzato, Claudia, Barbaglia, Michelangelo, Bardasi, Giulia, Barrani, Monica, Basso, Tiziano, Brach Del Prever, Adalberto, Belli, Fina, Bellomo Anna, Rita, Besenzon, Luigi, Biagioni, Martina, Bonaudo, Roberto, Bruni, Giulia, Brunori, Elena, Cagnoli, Giacomo, Campanozzi, Angelo, Casaccia, Germana, Castello, Mario, Chiaro, Andrea, Cimadore, Nicoletta, Cioni, Maddalena, Cortinovis, Francesca, De Cosmi, Valentina, De Giacomo, Costantino, Del Vecchio, Sergio, Diamanti, Antonella, Di Leo, Grazia, Di Scala, Carmen, Famiani, Annalisa, Felici, Enrico, Ferraris, Silvio, Fomasi, Martina, Fontanella, Giovanna, Frimaire, Alessia, Fusco, Patrizia, Galvagno, Graziana, Gandullia, Paolo, Gasparrini, Enrico, Guanã , Riccardo, Guerra, Azzurra, Lanari, Marcello, Lacitignola, Laura, Lezo, Antonella, Lizzoli, Francesca, Maggiore, Giuseppe, Magistã Anna, Maria, Malaventura, Cristina, Marmetucci, Luigi, Mazzocchi, Alessandra, Mazzoni, Elisa, Melli, Paola, Memmini, Graziano, Meneghini, Anna, Miglietti, Nunzia, Migliore, Giuseppina, Mistura, Laura, Monaci, Alessandro, Morganti, Alessia, Nesi, Francesca, Opinto, Vittoria, Pace, Mariella, Palamone, Gianluigi, Panceri, Roberto, Parisi, Giuseppe, Pastore, Maria, Penagini, Francesca, Perrone, Michela, Petitti, Patrizia, Pettinari, Chiara, Peverelli, Paola, Pinon, Michele, Russo, Carla, Sala, Alessandra, Salata, Michele, Salmaso, Mara, Sangerardi, Maria, Santangelo, Barbara, Savino, Francesco, Scatã , Donata, Siani, Paolo, Spagnuolo, Maria Immacolata, Sparano, Paola, Stamati Filomena, Andreina, Tulli, Monica, Uga, Elena, Urbano, Flavia, Verlato, Giovanna, Zoppo, Marisa, and Zuin, Giovanna

Subjects
0301 basic medicine, Male, Pediatrics, Hospitalized patients, Endocrinology, Diabetes and Metabolism, Pediatric nutrition, 0302 clinical medicine, Child Development, Endocrinology, Prevalence, 030212 general & internal medicine, Growth Charts, Child, Nutritional support, Wasting, Growth Disorders, Pediatric, Stunting, Nutrition and Dietetics, Nutritional status, Nutrition Surveys, Diabetes and Metabolism, Italy, Malnutrition, Child, Preschool, Female, medicine.symptom, medicine.medical_specialty, Adolescent, Nutritional Status, Socio-culturale, Malnutrition in children, 03 medical and health sciences, Young Adult, medicine, Humans, 030109 nutrition & dietetics, business.industry, Infant, Anthropometry, medicine.disease, Parenteral nutrition, Chronic Disease, business, Child, Hospitalized
Abstract

Introduction the prevalence of malnutrition in children and its impact on clinical outcomes is underrecognized by clinicians in Italy as well as worldwide. A novel definition of pediatric malnutrition has been recently proposed by a working group of the Academy of Nutrition and Dietetics and American Society for Parenteral and Enteral Nutrition (A.S.P.E.N.), based on the correlation between illness and the use of zscores of anthropometric measurements. Aim to investigate the prevalence of malnutrition and related nutritional support among hospitalized children in Italy, in a nationwide survey performed in a single day (16/4/2015). Methods an open access website (http://nday.biomedia.net) was used to collected data from 73 hospitals and 101 wards in 14 Italian regions (1994 patients). Anonymous information was collected on hospitals' characteristics, patient's anthropometry, admission diagnosis, presence of chronic diseases and use of nutritional support: oral nutritional supplements (ONS), enteral nutrition (EN) or parenteral nutrition (PN). Z-scores of anthropometric measurements, calculated with Epi Info 7.1.5, defined nutritional status: wasting was identified by BMI or Weight-for-Length z-score (

Published
2017

12. Paediatric Home Artificial Nutrition in Italy: Report from 2016 Survey on Behalf of Artificial Nutrition Network of Italian Society for Gastroenterology, Hepatology and Nutrition (SIGENP)

Author

Martina Mainetti, Simona Gatti, Ester Giaquinto, Sergio Amarri, Antonella Lezo, Laura Lacitignola, Maria Immacolata Spagnuolo, Maristella Pellegrino, Martina Fornaro, Maria Elisabetta Baldassarre, Maria Luisa Forchielli, B. Parma, Lorenzo Norsa, Paolo Gandullia, Irina Goreva, Marcello Lanari, Elisa Ravaioli, Teresa Capriati, Nicola Cecchi, Valeria Dipasquale, Grazia Di Leo, Silvia Salvatore, Antonella Diamanti, Elvira Verduci, Valentina Fiorito, Lezo, Antonella, Capriati, Teresa, Spagnuolo, Maria Immacolata, Lacitignola, Laura, Goreva, Irina, Di Leo, Grazia, Cecchi, Nicola, Gandullia, Paolo, Amarri, Sergio, Forchielli, Maria Luisa, Dipasquale, Valeria, Parma, Barbara, Gatti, Simona, Ravaioli, Elisa, Salvatore, Silvia, Mainetti, Martina, Norsa, Lorenzo, Pellegrino, Maristella, Fornaro, Martina, Fiorito, Valentina, Lanari, Marcello, Giaquinto, Ester, Verduci, Elvira, Baldassarre, Maria Elisabetta, and Diamanti, Antonella

Subjects
Home Care Service, Male, 0301 basic medicine, Time Factors, Children, Home enteral nutrition, Home parenteral nutrition, Oral nutritional supplements, Pediatrics, 0302 clinical medicine, Quality of life, Epidemiology, Age Factor, Child, Pediatric, Nutrition and Dietetics, Incidence (epidemiology), Age Factors, Home Care Services, Nutritional Statu, Italy, Child, Preschool, oral nutritional supplements, population characteristics, Female, 030211 gastroenterology & hepatology, Child Nutritional Physiological Phenomena, Parenteral Nutrition, Home, lcsh:Nutrition. Foods and food supply, geographic locations, Human, medicine.medical_specialty, Adolescent, Time Factor, Demographics, MEDLINE, Nutritional Status, lcsh:TX341-641, Oral nutritional supplement, Artificial nutrition, Article, Young Adult, 03 medical and health sciences, Enteral Nutrition, Internal medicine, medicine, Humans, 030109 nutrition & dietetics, business.industry, Infant, Newborn, nutritional and metabolic diseases, Infant, Hepatology, eye diseases, stomatognathic diseases, Parenteral nutrition, Health Care Survey, Health Care Surveys, Family medicine, business, Food Science
Abstract

Home Artificial Nutrition (HAN) is a safe and efficacious technique that insures children&rsquo, s reintegration into the family, society and school. Epidemiological data on paediatric HAN in Italy are not available. Aim: to detect the prevalence and incidence of Home Parenteral Nutrition (HPN) and Home Enteral Nutrition (HEN), either via tube or mouth, in Italy in 2016. Materials and methods: a specific form was sent to all registered SIGENP members and investigators of local HAN centres, inviting them to provide the requested centre&rsquo, s data and demographics, underlying diseases and HAN characteristics of the patients. Results: we recorded 3403 Italian patients on HAN aged 0 to 19 years from 22 centres: 2277 HEN, 950 Oral Nutritional Supplements (ONS) and 179 HPN programs. The prevalence of HEN (205 pts/million inhabitants) and HPN (16 pts/million inhabitants) has dramatically increased in Italy in the last 9 years. Neurodisabling conditions were the first indication for HEN by tube or mouth while HPN is mainly requested in digestive disorders. Conclusions: HAN is a widespread and rapidly growing treatment in Italy, as well as in other European countries. Awareness of its extent and characteristics helps improving HAN service and patients&rsquo, quality of life.

Published
2018

13. Loss of heterozygosity and p53 polymorphism Pro72Arg in a young patient with medulloblastoma.

Author

Sardi I, Giunti L, Donati P, Lacitignola L, Tucci F, Sardo L, Giovannucci Uzielli ML, and Bernini G

Subjects
Cerebellar Neoplasms therapy, Child, Chromosomes, Human, Pair 17, Diagnosis, Differential, Female, Headache etiology, Humans, Magnetic Resonance Imaging, Medulloblastoma therapy, Nausea etiology, Vomiting etiology, Cerebellar Neoplasms genetics, Genes, p53 genetics, Loss of Heterozygosity, Medulloblastoma genetics, Polymorphism, Genetic
Abstract

Differently from conventional primary neuroectodermal tumors (PNETs), molecular features of undifferentiated lesions have been poorly studied. Medulloblastoma and PNET neoplasms showed a high incidence of loss of heterozygosity (LOH) on chromosome 17p13, in the region of tumor suppressor gene p53. Recent studies have shown a significant correlation between the presence of p53 Arg72Pro polymorphism and several undifferentiated carcinomas. We performed molecular analysis in an anaplastic tumor of posterior fossa in a patient with a constitutional maternal translocation [46,XX,t(5;19)] and a history of headache, nausea and vomiting. We identified the presence of LOH at 17p13 and Pro72Arg polymorphism in tumor DNA. These molecular findings helped us better characterize this undifferentiated tumor and led to a more aggressive therapy.

Published
2003

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