363 results on '"La Gruta, Nicole L"'
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2. The molecular basis underlying T cell specificity towards citrullinated epitopes presented by HLA-DR4
3. Newborn and child-like molecular signatures in older adults stem from TCR shifts across human lifespan
4. The paradox of aging: Aging-related shifts in T cell function and metabolism
5. Checkpoint inhibitor immunotherapy diminishes oocyte number and quality in mice
6. Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection
7. Covalent TCR-peptide-MHC interactions induce T cell activation and redirect T cell fate in the thymus
8. Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host
9. 425.1: Single Cell Alloreactive TCR Repertoire Profiling
10. CD4⁺ T help promotes influenza virus-specific CD8⁺ T cell memory by limiting metabolic dysfunction
11. Most viral peptides displayed by class I MHC on infected cells are immunogenic
12. Simulation modelling for immunologists
13. T cell receptor recognition of hybrid insulin peptides bound to HLA-DQ8
14. Evaluation of inflammation and follicle depletion during ovarian ageing in mice
15. A subset of immune-system T cells branded as seeds for type 1 diabetes
16. Age-Related Decline in Primary CD8+ T Cell Responses Is Associated with the Development of Senescence in Virtual Memory CD8+ T Cells
17. Contribution of T Cell Receptor Affinity to Overall Avidity for Virus-Specific CD8+ T Cell Responses
18. Effector CD8 + T Cells Recovered from an Influenza Pneumonia Differentiate to a State of Focused Gene Expression
19. Differential Tumor Necrosis Factor Receptor 2-Mediated Editing of Virus-Specific CD8+ Effector T Cells
20. Publisher Correction: Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality
21. Metabolic characteristics of CD8+ T cell subsets in young and aged individuals are not predictive of functionality
22. Understanding the drivers of MHC restriction of T cell receptors
23. Re-evaluating the role of coreceptor: LCK association in T cell receptor signalling
24. Exploring the Role of T VMCells in Age-Related CD8 +T Cell Dysfunction through ATAC-seq and RNA-seq Analysis
25. Heightened self-reactivity associated with selective survival, but not expansion, of naïve virus-specific CD8⁺ T cells in aged mice
26. Helminth Infection–Induced Increase in Virtual Memory CD8 T Cells Is Transient, Driven by IL-15, and Absent in Aged Mice
27. TCR_Explore: A novel webtool for T cell receptor repertoire analysis
28. Targeted deletion of Traf2 allows immunosuppression-free islet allograft survival in mice
29. TCR_Explore: a novel webtool for T cell receptor repertoire analysis
30. T cell mediated immunity to influenza: mechanisms of viral control
31. Reproducible selection of high avidity CD8+ T-cell clones following secondary acute virus infection
32. Ecological analysis of antigen-specific CTL repertoires defines the relationship between naïve and immune T-cell populations
33. Sizing up the key determinants of the CD8+ T cell response
34. Structural basis for enabling T-cell receptor diversity within biased virus-specific CD8⁺ T-cell responses
35. A Trans-Golgi Network Golgin Is Required for the Regulated Secretion of TNF in Activated Macrophages in vivo
36. Epitope-Specific TCRβ Repertoire Diversity Imparts No Functional Advantage on the CD8⁺ T Cell Response to Cognate Viral Peptides
37. Dendritic Cell Preactivation Impairs MHC Class II Presentation of Vaccines and Endogenous Viral Antigens
38. A Virus-Specific CD8⁺ T Cell Immunodominance Hierarchy Determined by Antigen Dose and Precursor Frequencies
39. T-cell receptor recognition of HLA-DQ2–gliadin complexes associated with celiac disease
40. Targeting BMI-1 in B cells restores effective humoral immune responses and controls chronic viral infection
41. Paired TCRαβ analysis of virus-specific CD8+ T cells exposes diversity in a previously defined ‘narrow’ repertoire
42. The specificity of the CD4+ T cell response to gluten in children with coeliac disease is comparable to adults
43. Functional implications of T cell receptor diversity
44. Tracking phenotypically and functionally distinct T cell subsets via T cell repertoire diversity
45. Canonical T cell receptor docking on peptide–MHC is essential for T cell signaling
46. The shared susceptibility epitope of HLA-DR4 binds citrullinated self-antigens and the TCR
47. Publisher Correction: Metabolic characteristics of CD8 + T cell subsets in young and aged individuals are not predictive of functionality (Nature Communications, (2020), 11, 1, (2857), 10.1038/s41467-020-16633-7)
48. Quantifiable predictive features define epitope-specific T cell receptor repertoires
49. Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells
50. Thanks for the memories: Low-avidity T cells shine against escape variants.
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