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210 results on '"LA TORRE, Renato"'

5. Passive immunization during pregnancy for congenital cytomegalovirus infection

Author

Nigro, Giovanni, Adler, Stuart P., Best, Al M., and La Torre, Renato

Subjects
Cytomegalovirus infections -- Risk factors, Cytomegalovirus infections -- Diagnosis, Cytomegalovirus infections -- Care and treatment, Pregnant women -- Health aspects, Pregnancy, Complications of
Abstract

Pregnant women are treated for a primary cytomegalovirus (CMV) infection with intravenous CMV hyperimmune globulin. The method of treatment is found to be safe and it may be successful in treating and preventing congenital CMV infection in pregnant women.

Published
2005

9. Reverse end-diastolic flow in a fetus with a rare liver malformation: a case report

Author

La Torre Renato, Bisogni Francescantonio, Muto Brunella, Pasquali Gaia, D'Ambrosio Valentina, Spagnuolo Antonella, Giancotti Antonella, Anceschi Maurizio, and De Gado Fabrizio

Subjects
Medicine
Abstract

Abstract Introduction We describe a case of early and persistent reverse end-diastolic flow in the middle cerebral artery in a fetus with severe ascites. These features are associated with a rare liver malformation known as ductal plate malformation. Case presentation A 28-year-old Caucasian woman was referred to our high-risk obstetric unit at 24 weeks' gestation for fetal ascites detected during a routine ultrasound examination. During her hospitalization we performed medical investigations, including a fetal paracentesis, to detect the etiology of fetal ascites. The cause of fetal ascites (then considered non-immune or idiopathic) was not evident, but a subsequent ultrasound examination at 27 weeks' gestation showed a reverse end-diastolic flow in the middle cerebral artery without any other Doppler abnormalities. A cesarean section was performed at 28 weeks' gestation because of the compromised fetal condition. An autopsy revealed a rare malformation of intrahepatic bile ducts known as ductal plate malformation. Conclusion Persistent reverse flow in the middle cerebral artery should be considered a marker of adverse pregnancy outcome. We recommend careful ultrasound monitoring in the presence of this ultrasonographic sign to exclude any other cause of increased intracranial pressure. To better understand the nature of these ultrasonographic signs, additional reports are deemed necessary. In fact in our case, as confirmed by histopathological examination, the fetal condition was extremely compromised due to failure of the fetal liver. Ductal plate malformation altered the liver structures causing hypoproteinemia and probably portal hypertension. These two conditions therefore explain the severe hydrops that compromised the fetal situation.

Published
2011
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11. Ultrasound management and clinical outcome of twin pregnancies

Author

Giancotti, Antonella, Muto, B., Ambrosio, V. D., D'Ambrosio, Valentina, Diambrosio, V., Bevilacqua, Elisa, Pasquali, Gaia, Squarcella, Antonia, and LA TORRE, Renato

Subjects
Adult, medicine.medical_specialty, twin, multiple pregnancy, chorionicity, ultrasound, Ultrasonography, Prenatal, Pregnancy, medicine, Humans, Pregnancy outcomes, Retrospective Studies, Gynecology, Fetus, business.industry, Obstetrics, Perinatal complications, Ultrasound, Pregnancy Outcome, Obstetrics and Gynecology, Retrospective cohort study, medicine.disease, Perinatal morbidity, Pregnancy, Twin, Gestation, Female, business
Abstract

The rate of multiple pregnancies is showing a significant increase in Western countries. Twin gestations should be considered a high-risk condition because they are responsible for a disproportionate amount of overall perinatal morbidity and mortality. We used a specialised ultrasound protocol based on chorionicity to monitor 44 twin pregnancies (61% dichorionic diamniotic (DD) and 39% monochorionic diamniotic (MD)). Adverse pregnancy outcomes and pre-term deliveries were more common in MD pregnancies than in DD pregnancies; the rate of extreme pre-term delivery (< 32 weeks) was almost three-times higher in MD than in DD pregnancies (41% vs 15%) and perinatal complications were more frequent in MD than in DD pregnancies (59% vs 22%), but fetal anomalies were more frequent in DD than in MD pregnancies (30% vs 24%). Periodic ultrasound follow-up would predict the pregnancies that are at greater risk for fetal and neonatal complications and these should be monitored more closely.

Published
2013

12. Efficacy of three different antithrombotic regimens on pregnancy outcome in pregnant women affected by recurrent pregnancy loss

Author

Giancotti, Antonella, La Torre, R., LA TORRE, Renato, Spagnuolo, Antonella, D'Ambrosio, Valentina, Cerekja, A., PIAZZE GARMICA, Juan Josè, and Chistolini, Antonio

Subjects
Adult, medicine.medical_specialty, Abortion, Habitual, Reproductive age, Fibrinolytic Agents, Pregnancy, Antithrombotic, medicine, Secondary Prevention, Humans, Thrombophilia, Prospective Studies, prophylaxis, thrombosis, pregnancy loss, business.industry, Obstetrics, Pregnancy Complications, Hematologic, Pregnancy Outcome, Obstetrics and Gynecology, Heparin, medicine.disease, Thrombosis, Pediatrics, Perinatology and Child Health, Female, business, medicine.drug
Abstract

Recurrent pregnancy loss (RPL) is a common health problem affecting 1-5% of women at reproductive age.Evaluation of three different antithrombotic treatments in women with antecedent of RPL, comparing the results in negative and positive to thrombophilic screening pregnant women.We recruited 361 women with an antecedent of two or more pregnancy losses. From this group, 167 women became pregnant and considered for the study. The evaluated pregnant women were divided as negative/positive to thrombofilic screening: (a) 80 (48%) with negative thrombophilic screening, (b) 87 (52%) positive to thrombophilic screening. Pregnant women included in the study and considered negative or positive for thrombophilic screening, were randomized into three different therapy groups: (a) group 1: Acetil salicylic acid (ASA) 100 mg daily until third month of pregnancy, (b) group 2: low molecular-weight heparin (LMWH) - enoxaparine 40 mg daily until third month of pregnancy, (c) group 3: ASA 100 mg plus LMWH 40 mg daily until third month of pregnancy.In 80 negative to thrombophilic screening pregnant women, the comparison of efficacy of the three treatments, shows that all three treatment regimens were significantly effective comparing live births against fetal losses. In 87 positive to thrombophilic screening pregnant women, the comparison of efficacy for the three regimens, shows that the therapy with LMWH or LMWH plus ASA are significantly protective against fetal losses with respect to ASA, which showed a high number of fetal losses (11 live births, 18 fetal losses).We suggest that thromboprophylaxis is indicated in women with RPL independently from positiveness to thrombophilic markers.

Published
2011

14. Pfeiffer syndrome: literature review of prenatal sonographic findings and genetic diagnosis.

Author

Giancotti, Antonella, D’Ambrosio, Valentina, Marchionni, Enrica, Squarcella, Antonia, Aliberti, Camilla, La Torre, Renato, Manganaro, Lucia, Pizzuti, Antonio, D'Ambrosio, Valentina, and PECRAM Study Group*

Subjects
APERT syndrome, DIAGNOSTIC ultrasonic imaging, PRENATAL genetic testing, FIBROBLAST growth factor receptors, CRANIOSYNOSTOSES, SKULL abnormalities, ABORTION, CELL receptors, DIFFERENTIAL diagnosis, GESTATIONAL age, KARYOTYPES, MAGNETIC resonance imaging, GENETIC mutation, PRENATAL diagnosis, RADIOGRAPHY, ULTRASONIC imaging, ABNORMALITIES in the anatomical extremities, GENETICS, DIAGNOSIS
Abstract

Purpose: Pfeiffer syndrome (PS) is an autosomal dominant disorder caused by mutations in FGFR1 and FGFR2 genes. Given its wide range of clinical expression and severity, early prenatal diagnosis is difficult and genetic counseling is desirable. We report a literature review of all prenatal diagnosis of PS and a case report, with a focused description of ultrasound findings.Methods: After literature search, we selected 14 studies of antenatal diagnosis of PS. Prenatal ultrasound findings, outcome, maternal and obstetrical data and genetic tests were recorded and analyzed.Results: A total of 18 cases including the one we present were selected. Among the most frequent sonographic features, skull shape anomalies were evident in 72.2% of cases, nasal abnormalities in 50%, proptosis and hypertelorism in 44.4% and frontal bossing in 22.2%. Thumbs' anomalies were present in 33.3% of cases and toes' abnormalities in 38.9%. In all cases, postnatal or postmortem examination confirmed the prenatal diagnosis of PS.Conclusions: We provide a literature review of prenatal diagnosis of PS to identify ultrasound features that may be supportive in the diagnosis of this rare disease, helping in making a differential diagnosis with the other possible craniosynostosis syndromes and in suggesting gene molecular testing. [ABSTRACT FROM AUTHOR]

Published
2017
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16. Tronco arterioso comune: case report

Author

LA TORRE, Renato, Marchiani, E., Tinari, A., Mazzocco, Manuela, Pergolini, I., Anav, G., Lucchini, Renato, and Cosmi, Ermelando

Published
2003

18. MALFORMAZIONE

Author

Cosmi, Ermelando, LA TORRE, Renato, and COSMI E., Jr

Published
2000

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