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1. Velocity independent constraints on spin-dependent DM-nucleon interactions from IceCube and PICO

Author

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, C. Alispach, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, J. Auffenberg, S. Axani, P. Backes, H. Bagherpour, X. Bai, A. Balagopal V., A. Barbano, S. W. Barwick, B. Bastian, V. Baum, S. Baur, R. Bay, J. J. Beatty, K.-H. Becker, J. Becker Tjus, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, S. Böser, O. Botner, J. Böttcher, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, S. Bron, J. Brostean-Kaiser, A. Burgman, J. Buscher, R. S. Busse, T. Carver, C. Chen, E. Cheung, D. Chirkin, S. Choi, L. Classen, A. Coleman, G. H. Collin, J. M. Conrad, P. Coppin, P. Correa, D. F. Cowen, R. Cross, P. Dave, C. De Clercq, J. J. DeLaunay, H. Dembinski, K. Deoskar, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, A. Diaz, J. C. Díaz-Vélez, H. Dujmovic, M. Dunkman, E. Dvorak, B. Eberhardt, T. Ehrhardt, P. Eller, R. Engel, P. A. Evenson, S. Fahey, A. R. Fazely, J. Felde, K. Filimonov, C. Finley, A. Franckowiak, E. Friedman, A. Fritz, T. K. Gaisser, J. Gallagher, E. Ganster, S. Garrappa, L. Gerhardt, K. Ghorbani, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, S. Griswold, M. Günder, M. Gündüz, C. Haack, A. Hallgren, L. Halve, F. Halzen, K. Hanson, A. Haungs, D. Hebecker, D. Heereman, P. Heix, K. Helbing, R. Hellauer, F. Henningsen, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, T. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, F. Jonske, R. Joppe, D. Kang, W. Kang, A. Kappes, D. Kappesser, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, J. L. Kelley, A. Kheirandish, J. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, M. Kowalski, K. Krings, G. Krückl, N. Kulacz, N. Kurahashi, A. Kyriacou, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, J. P. Lazar, K. Leonard, A. Leszczynska, M. Leuermann, Q. R. Liu, E. Lohfink, C. J. Lozano Mariscal, L. Lu, F. Lucarelli, J. Lünemann, W. Luszczak, Y. Lyu, W. Y. Ma, J. Madsen, G. Maggi, K. B. M. Mahn, Y. Makino, P. Mallik, K. Mallot, S. Mancina, I. C. Mariş, R. Maruyama, K. Mase, R. Maunu, F. McNally, K. Meagher, M. Medici, A. Medina, M. Meier, S. Meighen-Berger, T. Menne, G. Merino, T. Meures, J. Micallef, G. Momenté, T. Montaruli, R. W. Moore, R. Morse, M. Moulai, P. Muth, R. Nagai, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, M. Oehler, A. Olivas, A. O’Murchadha, E. O’Sullivan, T. Palczewski, H. Pandya, D. V. Pankova, N. Park, P. Peiffer, C. Pérez de los Heros, S. Philippen, D. Pieloth, E. Pinat, A. Pizzuto, M. Plum, A. Porcelli, P. B. Price, G. T. Przybylski, C. Raab, A. Raissi, M. Rameez, L. Rauch, K. Rawlins, I. C. Rea, R. Reimann, B. Relethford, M. Renschler, G. Renzi, E. Resconi, W. Rhode, M. Richman, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, I. Safa, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Schaufel, H. Schieler, P. Schlunder, T. Schmidt, A. Schneider, J. Schneider, F. G. Schröder, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, S. Shefali, M. Silva, R. Snihur, J. Soedingrekso, D. Soldin, M. Song, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, R. Stein, P. Steinmüller, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stössl, N. L. Strotjohann, T. Stürwald, T. Stuttard, G. W. Sullivan, I. Taboada, F. Tenholt, S. Ter-Antonyan, A. Terliuk, S. Tilav, L. Tomankova, C. Tönnis, S. Toscano, D. Tosi, A. Trettin, M. Tselengidou, C. F. Tung, A. Turcati, R. Turcotte, C. F. Turley, B. Ty, E. Unger, M. A. Unland Elorrieta, M. Usner, J. Vandenbroucke, W. Van Driessche, D. van Eijk, N. van Eijndhoven, S. Vanheule, J. van Santen, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, N. Wandkowsky, T. B. Watson, C. Weaver, A. Weindl, M. J. Weiss, J. Weldert, C. Wendt, J. Werthebach, B. J. Whelan, N. Whitehorn, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, J. Wood, T. R. Wood, K. Woschnagg, G. Wrede, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, T. Yuan, M. Zöcklein, IceCube Collaboration, C. Amole, M. Ardid, I. J. Arnquist, D. M. Asner, D. Baxter, E. Behnke, M. Bressler, B. Broerman, G. Cao, C. J. Chen, U. Chowdhury, K. Clark, J. I. Collar, P. S. Cooper, M. Crisler, G. Crowder, N. A. Cruz-Venegas, C. E. Dahl, M. Das, S. Fallows, J. Farine, I. Felis, R. Filgas, F. Girard, G. Giroux, J. Hall, C. Hardy, O. Harris, E. W. Hoppe, M. Jin, L. Klopfenstein, C. B. Krauss, M. Laurin, I. Lawson, A. Leblanc, I. Levine, W. H. Lippincott, F. Mamedov, D. Maurya, P. Mitra, C. Moore, T. Nania, R. Neilson, A. J. Noble, P. Oedekerk, A. Ortega, M.-C. Piro, A. Plante, R. Podviyanuk, S. Priya, A. E. Robinson, S. Sahoo, O. Scallon, S. Seth, A. Sonnenschein, N. Starinski, I. Štekl, T. Sullivan, F. Tardif, E. Vázquez-Jáuregui, N. Walkowski, U. Wichoski, Y. Yan, V. Zacek, J. Zhang, and PICO Collaboration

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract Adopting the Standard Halo Model (SHM) of an isotropic Maxwellian velocity distribution for dark matter (DM) particles in the Galaxy, the most stringent current constraints on their spin-dependent scattering cross-section with nucleons come from the IceCube neutrino observatory and the PICO-60 $$\hbox {C}_3\hbox {F}_8$$ C 3 F 8 superheated bubble chamber experiments. The former is sensitive to high energy neutrinos from the self-annihilation of DM particles captured in the Sun, while the latter looks for nuclear recoil events from DM scattering off nucleons. Although slower DM particles are more likely to be captured by the Sun, the faster ones are more likely to be detected by PICO. Recent N-body simulations suggest significant deviations from the SHM for the smooth halo component of the DM, while observations hint at a dominant fraction of the local DM being in substructures. We use the method of Ferrer et al. (JCAP 1509: 052, 2015) to exploit the complementarity between the two approaches and derive conservative constraints on DM-nucleon scattering. Our results constrain $$\sigma _{\mathrm{SD}} \lesssim 3 \times 10^{-39} \mathrm {cm}^2$$ σ SD ≲ 3 × 10 - 39 cm 2 ( $$6 \times 10^{-38} \mathrm {cm}^2$$ 6 × 10 - 38 cm 2 ) at $$\gtrsim 90\%$$ ≳ 90 % C.L. for a DM particle of mass 1 TeV annihilating into $$\tau ^+ \tau ^-$$ τ + τ - ( $$b\bar{b}$$ b b ¯ ) with a local density of $$\rho _{\mathrm{DM}} = 0.3~\mathrm {GeV/cm}^3$$ ρ DM = 0.3 GeV / cm 3 . The constraints scale inversely with $$\rho _{\mathrm{DM}}$$ ρ DM and are independent of the DM velocity distribution.

Published
2020
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2. Development of an analysis to probe the neutrino mass ordering with atmospheric neutrinos using three years of IceCube DeepCore data

Author

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, C. Alispach, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, J. Auffenberg, S. Axani, P. Backes, H. Bagherpour, X. Bai, A. Barbano, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, K.-H. Becker, J. Becker Tjus, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, S. Böser, O. Botner, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, H.-P. Bretz, S. Bron, J. Brostean-Kaiser, A. Burgman, R. S. Busse, T. Carver, C. Chen, E. Cheung, D. Chirkin, K. Clark, L. Classen, G. H. Collin, J. M. Conrad, P. Coppin, P. Correa, D. F. Cowen, R. Cross, P. Dave, J. P. A. M. de André, C. De Clercq, J. J. DeLaunay, H. Dembinski, K. Deoskar, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, A. Diaz, J. C. Díaz-Vélez, H. Dujmovic, M. Dunkman, E. Dvorak, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, J. J. Evans, P. A. Evenson, S. Fahey, A. R. Fazely, J. Felde, K. Filimonov, C. Finley, A. Franckowiak, E. Friedman, A. Fritz, T. K. Gaisser, J. Gallagher, E. Ganster, S. Garrappa, L. Gerhardt, K. Ghorbani, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, M. Günder, M. Gündüz, C. Haack, A. Hallgren, L. Halve, F. Halzen, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, F. Henningsen, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, W. Kang, A. Kappes, D. Kappesser, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, J. L. Kelley, A. Kheirandish, J. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, M. Kowalski, K. Krings, G. Krückl, N. Kulacz, S. Kunwar, N. Kurahashi, A. Kyriacou, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, J. P. Lazar, K. Leonard, M. Leuermann, Q. R. Liu, E. Lohfink, C. J. Lozano Mariscal, L. Lu, F. Lucarelli, J. Lünemann, W. Luszczak, J. Madsen, G. Maggi, K. B. M. Mahn, Y. Makino, K. Mallot, S. Mancina, I. C. Mariş, R. Maruyama, K. Mase, R. Maunu, K. Meagher, M. Medici, A. Medina, M. Meier, S. Meighen-Berger, T. Menne, G. Merino, T. Meures, S. Miarecki, J. Micallef, G. Momenté, T. Montaruli, R. W. Moore, M. Moulai, R. Nagai, R. Nahnhauer, P. Nakarmi, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, E. O’Sullivan, T. Palczewski, H. Pandya, D. V. Pankova, N. Park, P. Peiffer, C. Pérez de los Heros, D. Pieloth, E. Pinat, A. Pizzuto, M. Plum, P. B. Price, G. T. Przybylski, C. Raab, A. Raissi, M. Rameez, L. Rauch, K. Rawlins, I. C. Rea, R. Reimann, B. Relethford, G. Renzi, E. Resconi, W. Rhode, M. Richman, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, I. Safa, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Schaufel, P. Schlunder, T. Schmidt, A. Schneider, J. Schneider, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, M. Silva, R. Snihur, J. Soedingrekso, D. Soldin, S. Söldner-Rembold, M. Song, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, A. Stasik, R. Stein, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, N. L. Strotjohann, T. Stuttard, G. W. Sullivan, M. Sutherland, I. Taboada, F. Tenholt, S. Ter-Antonyan, A. Terliuk, S. Tilav, L. Tomankova, C. Tönnis, S. Toscano, D. Tosi, M. Tselengidou, C. F. Tung, A. Turcati, R. Turcotte, C. F. Turley, B. Ty, E. Unger, M. A. Unland Elorrieta, M. Usner, J. Vandenbroucke, W. Van Driessche, D. van Eijk, N. van Eijndhoven, S. Vanheule, J. van Santen, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, N. Wandkowsky, T. B. Watson, C. Weaver, M. J. Weiss, J. Weldert, C. Wendt, J. Werthebach, S. Westerhoff, B. J. Whelan, N. Whitehorn, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, J. Wood, T. R. Wood, K. Woschnagg, G. Wrede, S. Wren, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, and T. Yuan

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The Neutrino Mass Ordering (NMO) remains one of the outstanding questions in the field of neutrino physics. One strategy to measure the NMO is to observe matter effects in the oscillation pattern of atmospheric neutrinos above $$\sim 1\,\mathrm {GeV}$$ ∼1GeV , as proposed for several next-generation neutrino experiments. Moreover, the existing IceCube DeepCore detector can already explore this type of measurement. We present the development and application of two independent analyses to search for the signature of the NMO with three years of DeepCore data. These analyses include a full treatment of systematic uncertainties and a statistically-rigorous method to determine the significance for the NMO from a fit to the data. Both analyses show that the dataset is fully compatible with both mass orderings. For the more sensitive analysis, we observe a preference for normal ordering with a p-value of $$p_\mathrm {IO} = 15.3\%$$ pIO=15.3% and $$\mathrm {CL}_\mathrm {s}=53.3\%$$ CLs=53.3% for the inverted ordering hypothesis, while the experimental results from both analyses are consistent within their uncertainties. Since the result is independent of the value of $$\delta _\mathrm {CP}$$ δCP and obtained from energies $$E_\nu \gtrsim 5\,\mathrm {GeV}$$ Eν≳5GeV , it is complementary to recent results from long-baseline experiments. These analyses set the groundwork for the future of this measurement with more capable detectors, such as the IceCube Upgrade and the proposed PINGU detector.

Published
2020
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3. Search for steady point-like sources in the astrophysical muon neutrino flux with 8 years of IceCube data

Author

IceCube Collaboration, M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, D. Altmann, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, J. Auffenberg, S. Axani, P. Backes, H. Bagherpour, X. Bai, A. Barbano, J. P. Barron, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, J. Becker Tjus, K.-H. Becker, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, F. Bos, S. Böser, O. Botner, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, H.-P. Bretz, S. Bron, J. Brostean-Kaiser, A. Burgman, R. S. Busse, T. Carver, C. Chen, E. Cheung, D. Chirkin, K. Clark, L. Classen, G. H. Collin, J. M. Conrad, P. Coppin, P. Correa, D. F. Cowen, R. Cross, P. Dave, M. Day, J. P. A. M. de André, C. De Clercq, J. J. DeLaunay, H. Dembinski, K. Deoskar, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, J. C. Díaz-Vélez, H. Dujmovic, M. Dunkman, E. Dvorak, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, P. A. Evenson, S. Fahey, A. R. Fazely, J. Felde, K. Filimonov, C. Finley, A. Franckowiak, E. Friedman, A. Fritz, T. K. Gaisser, J. Gallagher, E. Ganster, S. Garrappa, L. Gerhardt, K. Ghorbani, W. Giang, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, C. Haack, A. Hallgren, L. Halve, F. Halzen, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, P. Kalaczynski, W. Kang, A. Kappes, D. Kappesser, T. Karg, A. Karle, U. Katz, M. Kauer, A. Keivani, J. L. Kelley, A. Kheirandish, J. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, M. Kowalski, K. Krings, M. Kroll, G. Krückl, S. Kunwar, N. Kurahashi, A. Kyriacou, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, K. Leonard, M. Leuermann, Q. R. Liu, E. Lohfink, C. J. Lozano Mariscal, L. Lu, J. Lünemann, W. Luszczak, J. Madsen, G. Maggi, K. B. M. Mahn, Y. Makino, S. Mancina, I. C. Mariş, R. Maruyama, K. Mase, R. Maunu, K. Meagher, M. Medici, M. Meier, T. Menne, G. Merino, T. Meures, S. Miarecki, J. Micallef, G. Momenté, T. Montaruli, R. W. Moore, M. Moulai, R. Nagai, R. Nahnhauer, P. Nakarmi, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, E. O’Sullivan, T. Palczewski, H. Pandya, D. V. Pankova, P. Peiffer, C. Pérez de los Heros, D. Pieloth, E. Pinat, A. Pizzuto, M. Plum, P. B. Price, G. T. Przybylski, C. Raab, M. Rameez, L. Rauch, K. Rawlins, I. C. Rea, R. Reimann, B. Relethford, G. Renzi, E. Resconi, W. Rhode, M. Richman, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, I. Safa, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Schaufel, P. Schlunder, T. Schmidt, A. Schneider, J. Schneider, S. Schöneberg, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, J. Soedingrekso, D. Soldin, M. Song, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, A. Stasik, R. Stein, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, N. L. Strotjohann, T. Stuttard, G. W. Sullivan, M. Sutherland, I. Taboada, F. Tenholt, S. Ter-Antonyan, A. Terliuk, S. Tilav, M. N. Tobin, C. Tönnis, S. Toscano, D. Tosi, M. Tselengidou, C. F. Tung, A. Turcati, R. Turcotte, C. F. Turley, B. Ty, E. Unger, M. A. Unland Elorrieta, M. Usner, J. Vandenbroucke, W. Van Driessche, D. van Eijk, N. van Eijndhoven, S. Vanheule, J. van Santen, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, F. D. Wandler, N. Wandkowsky, T. B. Watson, C. Weaver, M. J. Weiss, C. Wendt, J. Werthebach, S. Westerhoff, B. J. Whelan, N. Whitehorn, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, J. Wood, T. R. Wood, E. Woolsey, K. Woschnagg, G. Wrede, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, and T. Yuan

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract The IceCube Collaboration has observed a high-energy astrophysical neutrino flux and recently found evidence for neutrino emission from the blazar TXS 0506$$+$$ + 056. These results open a new window into the high-energy universe. However, the source or sources of most of the observed flux of astrophysical neutrinos remains uncertain. Here, a search for steady point-like neutrino sources is performed using an unbinned likelihood analysis. The method searches for a spatial accumulation of muon-neutrino events using the very high-statistics sample of about 497,000 neutrinos recorded by IceCube between 2009 and 2017. The median angular resolution is $$\sim 1^\circ $$ ∼1∘ at 1 TeV and improves to $$\sim 0.3^\circ $$ ∼0.3∘ for neutrinos with an energy of 1 PeV. Compared to previous analyses, this search is optimized for point-like neutrino emission with the same flux-characteristics as the observed astrophysical muon-neutrino flux and introduces an improved event-reconstruction and parametrization of the background. The result is an improvement in sensitivity to the muon-neutrino flux compared to the previous analysis of $$\sim 35\%$$ ∼35% assuming an $$E^{-2}$$ E-2 spectrum. The sensitivity on the muon-neutrino flux is at a level of $$E^2 \mathrm {d} N /\mathrm {d} E = 3\cdot 10^{-13}\,\mathrm {TeV}\,\mathrm {cm}^{-2}\,\mathrm {s}^{-1}$$ E2dN/dE=3·10-13TeVcm-2s-1 . No new evidence for neutrino sources is found in a full sky scan and in an a priori candidate source list that is motivated by gamma-ray observations. Furthermore, no significant excesses above background are found from populations of sub-threshold sources. The implications of the non-observation for potential source classes are discussed.

Published
2019
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4. Erratum to: Search for annihilating dark matter in the Sun with 3 years of IceCube data

Author

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, D. Altmann, K. Andeen, T. Anderson, I. Ansseau, G. Anton, M. Archinger, C. Argüelles, J. Auffenberg, S. Axani, X. Bai, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, J. Becker Tjus, K.-H. Becker, S. BenZvi, D. Berley, E. Bernardini, A. Bernhard, D. Z. Besson, G. Binder, D. Bindig, M. Bissok, E. Blaufuss, S. Blot, C. Bohm, M. Börner, F. Bos, D. Bose, S. Böser, O. Botner, J. Braun, L. Brayeur, H.-P. Bretz, S. Bron, A. Burgman, T. Carver, M. Casier, E. Cheung, D. Chirkin, A. Christov, K. Clark, L. Classen, S. Coenders, G. H. Collin, J. M. Conrad, D. F. Cowen, R. Cross, M. Day, J. P. A. M. de André, C. De Clercq, E. del Pino Rosendo, H. Dembinski, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, J. C. Díaz-Vélez, V. di Lorenzo, H. Dujmovic, J. P. Dumm, M. Dunkman, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, S. Euler, P. A. Evenson, S. Fahey, A. R. Fazely, J. Feintzeig, J. Felde, K. Filimonov, C. Finley, S. Flis, C.-C. Fösig, A. Franckowiak, E. Friedman, T. Fuchs, T. K. Gaisser, J. Gallagher, L. Gerhardt, K. Ghorbani, W. Giang, L. Gladstone, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, C. Haack, A. Hallgren, F. Halzen, E. Hansen, T. Hansmann, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, S. In, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, W. Kang, A. Kappes, T. Karg, A. Karle, U. Katz, M. Kauer, A. Keivani, J. L. Kelley, A. Kheirandish, J. Kim, M. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, G. Kohnen, R. Koirala, H. Kolanoski, R. Konietz, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, M. Kowalski, K. Krings, M. Kroll, G. Krückl, C. Krüger, J. Kunnen, S. Kunwar, N. Kurahashi, T. Kuwabara, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, D. Lennarz, M. Lesiak-Bzdak, M. Leuermann, L. Lu, J. Lünemann, J. Madsen, G. Maggi, K. B. M. Mahn, S. Mancina, M. Mandelartz, R. Maruyama, K. Mase, R. Maunu, F. McNally, K. Meagher, M. Medici, M. Meier, A. Meli, T. Menne, G. Merino, T. Meures, S. Miarecki, T. Montaruli, M. Moulai, R. Nahnhauer, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, T. Palczewski, H. Pandya, D. V. Pankova, P. Peiffer, Ö. Penek, J. A. Pepper, C. Pérez de los Heros, D. Pieloth, E. Pinat, P. B. Price, G. T. Przybylski, M. Quinnan, C. Raab, L. Rädel, M. Rameez, K. Rawlins, R. Reimann, B. Relethford, M. Relich, E. Resconi, W. Rhode, M. Richman, B. Riedel, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, L. Sabbatini, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, S. Sarkar, K. Satalecka, P. Schlunder, T. Schmidt, S. Schoenen, S. Schöneberg, L. Schumacher, D. Seckel, S. Seunarine, D. Soldin, M. Song, G. M. Spiczak, C. Spiering, T. Stanev, A. Stasik, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, R. Ström, N. L. Strotjohann, G. W. Sullivan, M. Sutherland, H. Taavola, I. Taboada, J. Tatar, F. Tenholt, S. Ter-Antonyan, A. Terliuk, G. Tešić, S. Tilav, P. A. Toale, M. N. Tobin, S. Toscano, D. Tosi, M. Tselengidou, A. Turcati, E. Unger, M. Usner, J. Vandenbroucke, N. van Eijndhoven, S. Vanheule, M. van Rossem, J. van Santen, M. Vehring, M. Voge, E. Vogel, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, N. Wandkowsky, Ch. Weaver, M. J. Weiss, C. Wendt, S. Westerhoff, B. J. Whelan, S. Wickmann, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, T. R. Wood, E. Woolsey, K. Woschnagg, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, and M. Zoll

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

In the analysis published in 1, constraints on the number of signal events can be interpreted as constraints on the volumetric neutrino to muon conversion rate.

Published
2019
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5. Search for neutrinos from decaying dark matter with IceCube

Author

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, I. Al Samarai, D. Altmann, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, J. Auffenberg, S. Axani, P. Backes, H. Bagherpour, X. Bai, J. P. Barron, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, J. Becker Tjus, K.-H. Becker, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, F. Bos, S. Böser, O. Botner, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, M. Brenzke, H.-P. Bretz, S. Bron, J. Brostean-Kaiser, A. Burgman, R. S. Busse, T. Carver, E. Cheung, D. Chirkin, A. Christov, K. Clark, L. Classen, G. H. Collin, J. M. Conrad, P. Coppin, P. Correa, D. F. Cowen, R. Cross, P. Dave, M. Day, J. P. A. M. de André, C. De Clercq, J. J. DeLaunay, H. Dembinski, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, J. C. Díaz-Vélez, V. di Lorenzo, H. Dujmovic, J. P. Dumm, M. Dunkman, E. Dvorak, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, P. A. Evenson, S. Fahey, A. R. Fazely, J. Felde, K. Filimonov, C. Finley, S. Flis, A. Franckowiak, E. Friedman, A. Fritz, T. K. Gaisser, J. Gallagher, E. Ganster, L. Gerhardt, K. Ghorbani, W. Giang, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, C. Haack, A. Hallgren, L. Halve, F. Halzen, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, P. Kalaczynski, W. Kang, A. Kappes, D. Kappesser, T. Karg, A. Karle, U. Katz, M. Kauer, A. Keivani, J. L. Kelley, A. Kheirandish, J. Kim, M. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, J. P. Koschinsky, D. J. Koskinen, M. Kowalski, K. Krings, M. Kroll, G. Krückl, S. Kunwar, N. Kurahashi, T. Kuwabara, A. Kyriacou, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, K. Leonard, M. Lesiak-Bzdak, M. Leuermann, Q. R. Liu, E. Lohfink, C. J. Lozano Mariscal, L. Lu, J. Lünemann, W. Luszczak, J. Madsen, G. Maggi, K. B. M. Mahn, S. Mancina, R. Maruyama, K. Mase, R. Maunu, K. Meagher, M. Medici, M. Meier, T. Menne, G. Merino, T. Meures, S. Miarecki, J. Micallef, G. Momenté, T. Montaruli, R. W. Moore, M. Moulai, R. Nahnhauer, P. Nakarmi, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, E. O’Sullivan, T. Palczewski, H. Pandya, D. V. Pankova, P. Peiffer, J. A. Pepper, C. Pérez de los Heros, D. Pieloth, E. Pinat, M. Plum, P. B. Price, G. T. Przybylski, C. Raab, L. Rädel, M. Rameez, L. Rauch, K. Rawlins, I. C. Rea, R. Reimann, B. Relethford, M. Relich, E. Resconi, W. Rhode, M. Richman, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, I. Safa, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Schaufel, P. Schlunder, T. Schmidt, A. Schneider, S. Schoenen, S. Schöneberg, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, J. Soedingrekso, D. Soldin, M. Song, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, A. Stasik, R. Stein, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, N. L. Strotjohann, T. Stuttard, G. W. Sullivan, M. Sutherland, I. Taboada, J. Tatar, F. Tenholt, S. Ter-Antonyan, A. Terliuk, S. Tilav, P. A. Toale, M. N. Tobin, C. Tönnis, S. Toscano, D. Tosi, M. Tselengidou, C. F. Tung, A. Turcati, C. F. Turley, B. Ty, E. Unger, M. Usner, J. Vandenbroucke, W. Van Driessche, D. van Eijk, N. van Eijndhoven, S. Vanheule, J. van Santen, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, F. D. Wandler, N. Wandkowsky, A. Waza, C. Weaver, M. J. Weiss, C. Wendt, J. Werthebach, S. Westerhoff, B. J. Whelan, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, J. Wood, T. R. Wood, E. Woolsey, K. Woschnagg, G. Wrede, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, and T. Yuan

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract With the observation of high-energy astrophysical neutrinos by the IceCube Neutrino Observatory, interest has risen in models of PeV-mass decaying dark matter particles to explain the observed flux. We present two dedicated experimental analyses to test this hypothesis. One analysis uses 6 years of IceCube data focusing on muon neutrino ‘track’ events from the Northern Hemisphere, while the second analysis uses 2 years of ‘cascade’ events from the full sky. Known background components and the hypothetical flux from unstable dark matter are fitted to the experimental data. Since no significant excess is observed in either analysis, lower limits on the lifetime of dark matter particles are derived: we obtain the strongest constraint to date, excluding lifetimes shorter than $$10^{28}\hbox { s}$$ 1028s at 90% CL for dark matter masses above $$10~\hbox {TeV}$$ 10TeV .

Published
2018
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6. Measurement of the $$\nu _{\mu }$$ νμ energy spectrum with IceCube-79

Author

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, I. Al Samarai, D. Altmann, K. Andeen, T. Anderson, I. Ansseau, G. Anton, M. Archinger, C. Argüelles, J. Auffenberg, S. Axani, H. Bagherpour, X. Bai, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, J. Becker Tjus, K.-H. Becker, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, F. Bos, D. Bose, S. Böser, O. Botner, F. Bradascio, J. Braun, L. Brayeur, H.-P. Bretz, S. Bron, A. Burgman, T. Carver, M. Casier, E. Cheung, D. Chirkin, A. Christov, K. Clark, L. Classen, S. Coenders, G. H. Collin, J. M. Conrad, D. F. Cowen, R. Cross, M. Day, J. P. A. M. de André, C. De Clercq, E. del Pino Rosendo, H. Dembinski, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, J. C. Díaz-Vélez, V. di Lorenzo, H. Dujmovic, J. P. Dumm, M. Dunkman, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, S. Euler, P. A. Evenson, S. Fahey, A. R. Fazely, J. Feintzeig, J. Felde, K. Filimonov, C. Finley, S. Flis, C.-C. Fösig, A. Franckowiak, E. Friedman, T. Fuchs, T. K. Gaisser, J. Gallagher, L. Gerhardt, K. Ghorbani, W. Giang, L. Gladstone, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, C. Haack, A. Hallgren, F. Halzen, E. Hansen, T. Hansmann, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, S. In, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, W. Kang, A. Kappes, T. Karg, A. Karle, U. Katz, M. Kauer, A. Keivani, J. L. Kelley, A. Kheirandish, J. Kim, M. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, G. Kohnen, R. Koirala, H. Kolanoski, R. Konietz, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, M. Kowalski, K. Krings, M. Kroll, G. Krückl, C. Krüger, J. Kunnen, S. Kunwar, N. Kurahashi, T. Kuwabara, A. Kyriacou, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, D. Lennarz, M. Lesiak-Bzdak, M. Leuermann, L. Lu, J. Lünemann, J. Madsen, G. Maggi, K. B. M. Mahn, S. Mancina, R. Maruyama, K. Mase, R. Maunu, F. McNally, K. Meagher, M. Medici, M. Meier, T. Menne, G. Merino, T. Meures, S. Miarecki, J. Micallef, G. Momenté, T. Montaruli, M. Moulai, R. Nahnhauer, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, T. Palczewski, H. Pandya, D. V. Pankova, P. Peiffer, Ö. Penek, J. A. Pepper, C. Pérez de los Heros, D. Pieloth, E. Pinat, P. B. Price, G. T. Przybylski, M. Quinnan, C. Raab, L. Rädel, M. Rameez, K. Rawlins, R. Reimann, B. Relethford, M. Relich, E. Resconi, W. Rhode, M. Richman, B. Riedel, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, L. Sabbatini, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, S. Sarkar, K. Satalecka, P. Schlunder, T. Schmidt, S. Schoenen, S. Schöneberg, L. Schumacher, D. Seckel, S. Seunarine, D. Soldin, M. Song, G. M. Spiczak, C. Spiering, J. Stachurska, T. Stanev, A. Stasik, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, R. Ström, N. L. Strotjohann, G. W. Sullivan, M. Sutherland, H. Taavola, I. Taboada, J. Tatar, F. Tenholt, S. Ter-Antonyan, A. Terliuk, G. Tešić, S. Tilav, P. A. Toale, M. N. Tobin, S. Toscano, D. Tosi, M. Tselengidou, C. F. Tung, A. Turcati, E. Unger, M. Usner, J. Vandenbroucke, N. van Eijndhoven, S. Vanheule, M. van Rossem, J. van Santen, M. Vehring, M. Voge, E. Vogel, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, N. Wandkowsky, A. Waza, Ch. Weaver, M. J. Weiss, C. Wendt, S. Westerhoff, B. J. Whelan, S. Wickmann, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, T. R. Wood, E. Woolsey, K. Woschnagg, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, and M. Zoll

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract IceCube is a neutrino observatory deployed in the glacial ice at the geographic South Pole. The $$\nu _\mu $$ νμ energy unfolding described in this paper is based on data taken with IceCube in its 79-string configuration. A sample of muon neutrino charged-current interactions with a purity of 99.5% was selected by means of a multivariate classification process based on machine learning. The subsequent unfolding was performed using the software Truee. The resulting spectrum covers an E$$_\nu $$ ν -range of more than four orders of magnitude from 125 GeV to 3.2 PeV. Compared to the Honda atmospheric neutrino flux model, the energy spectrum shows an excess of more than $$1.9\,\sigma $$ 1.9σ in four adjacent bins for neutrino energies $$E_\nu \ge 177.8\,\text {TeV}$$ Eν≥177.8TeV . The obtained spectrum is fully compatible with previous measurements of the atmospheric neutrino flux and recent IceCube measurements of a flux of high-energy astrophysical neutrinos.

Published
2017
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7. Search for neutrinos from dark matter self-annihilations in the center of the Milky Way with 3 years of IceCube/DeepCore

Author

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, I. Al Samarai, D. Altmann, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, J. Auffenberg, S. Axani, H. Bagherpour, X. Bai, J. P. Barron, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, J. Becker Tjus, K. -H. Becker, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, F. Bos, D. Bose, S. Böser, O. Botner, J. Bourbeau, F. Bradascio, J. Braun, L. Brayeur, M. Brenzke, H. -P. Bretz, S. Bron, A. Burgman, T. Carver, J. Casey, M. Casier, E. Cheung, D. Chirkin, A. Christov, K. Clark, L. Classen, S. Coenders, G. H. Collin, J. M. Conrad, D. F. Cowen, R. Cross, M. Day, J. P. A. M. de André, C. De Clercq, J. J. DeLaunay, H. Dembinski, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, J. C. Díaz-Vélez, V. di Lorenzo, H. Dujmovic, J. P. Dumm, M. Dunkman, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, P. A. Evenson, S. Fahey, A. R. Fazely, J. Felde, K. Filimonov, C. Finley, S. Flis, A. Franckowiak, E. Friedman, T. Fuchs, T. K. Gaisser, J. Gallagher, L. Gerhardt, K. Ghorbani, W. Giang, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, C. Haack, A. Hallgren, F. Halzen, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, S. In, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, P. Kalacynski, W. Kang, A. Kappes, T. Karg, A. Karle, U. Katz, M. Kauer, A. Keivani, J. L. Kelley, A. Kheirandish, J. Kim, M. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, G. Kohnen, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, J. P. Koschinsky, D. J. Koskinen, M. Kowalski, K. Krings, M. Kroll, G. Krückl, J. Kunnen, S. Kunwar, N. Kurahashi, T. Kuwabara, A. Kyriacou, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, D. Lennarz, M. Lesiak-Bzdak, M. Leuermann, Q. R. Liu, L. Lu, J. Lünemann, W. Luszczak, J. Madsen, G. Maggi, K. B. M. Mahn, S. Mancina, R. Maruyama, K. Mase, R. Maunu, F. McNally, K. Meagher, M. Medici, M. Meier, T. Menne, G. Merino, T. Meures, S. Miarecki, J. Micallef, G. Momenté, T. Montaruli, R. W. Moore, M. Moulai, R. Nahnhauer, P. Nakarmi, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, T. Palczewski, H. Pandya, D. V. Pankova, P. Peiffer, J. A. Pepper, C. Pérez de los Heros, D. Pieloth, E. Pinat, M. Plum, P. B. Price, G. T. Przybylski, C. Raab, L. Rädel, M. Rameez, K. Rawlins, R. Reimann, B. Relethford, M. Relich, E. Resconi, W. Rhode, M. Richman, B. Riedel, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, T. Sälzer, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, S. Sarkar, K. Satalecka, P. Schlunder, T. Schmidt, A. Schneider, S. Schoenen, S. Schöneberg, L. Schumacher, D. Seckel, S. Seunarine, D. Soldin, M. Song, G. M. Spiczak, C. Spiering, J. Stachurska, T. Stanev, A. Stasik, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, N. L. Strotjohann, G. W. Sullivan, M. Sutherland, I. Taboada, J. Tatar, F. Tenholt, S. Ter-Antonyan, A. Terliuk, G. Tešić, S. Tilav, P. A. Toale, M. N. Tobin, S. Toscano, D. Tosi, M. Tselengidou, C. F. Tung, A. Turcati, C. F. Turley, B. Ty, E. Unger, M. Usner, J. Vandenbroucke, W. Van Driessche, N. van Eijndhoven, S. Vanheule, J. van Santen, M. Vehring, E. Vogel, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, F. D. Wandler, N. Wandkowsky, A. Waza, C. Weaver, M. J. Weiss, C. Wendt, S. Westerhoff, B. J. Whelan, S. Wickmann, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, J. Wood, T. R. Wood, E. Woolsey, K. Woschnagg, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, T. Yuan, and M. Zoll

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We present a search for a neutrino signal from dark matter self-annihilations in the Milky Way using the IceCube Neutrino Observatory (IceCube). In 1005 days of data we found no significant excess of neutrinos over the background of neutrinos produced in atmospheric air showers from cosmic ray interactions. We derive upper limits on the velocity averaged product of the dark matter self-annihilation cross section and the relative velocity of the dark matter particles $$\langle \sigma _{\text {A}}v\rangle $$ ⟨ σ A v ⟩ . Upper limits are set for dark matter particle candidate masses ranging from 10 GeV up to 1 TeV while considering annihilation through multiple channels. This work sets the most stringent limit on a neutrino signal from dark matter with mass between 10 and 100 GeV, with a limit of $$1.18\cdot 10^{-23}\text { cm}^3\text {s}^{-1}$$ 1.18 · 10 - 23 cm 3 s - 1 for 100 GeV dark matter particles self-annihilating via $$\tau ^+\tau ^-$$ τ + τ - to neutrinos (assuming the Navarro–Frenk–White dark matter halo profile).

Published
2017
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8. Search for annihilating dark matter in the Sun with 3 years of IceCube data

Author

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, D. Altmann, K. Andeen, T. Anderson, I. Ansseau, G. Anton, M. Archinger, C. Argüelles, J. Auffenberg, S. Axani, X. Bai, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, J. Becker Tjus, K.-H. Becker, S. BenZvi, D. Berley, E. Bernardini, A. Bernhard, D. Z. Besson, G. Binder, D. Bindig, M. Bissok, E. Blaufuss, S. Blot, C. Bohm, M. Börner, F. Bos, D. Bose, S. Böser, O. Botner, J. Braun, L. Brayeur, H.-P. Bretz, S. Bron, A. Burgman, T. Carver, M. Casier, E. Cheung, D. Chirkin, A. Christov, K. Clark, L. Classen, S. Coenders, G. H. Collin, J. M. Conrad, D. F. Cowen, R. Cross, M. Day, J. P. A. M. de André, C. De Clercq, E. del Pino Rosendo, H. Dembinski, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, J. C. Díaz-Vélez, V. di Lorenzo, H. Dujmovic, J. P. Dumm, M. Dunkman, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, S. Euler, P. A. Evenson, S. Fahey, A. R. Fazely, J. Feintzeig, J. Felde, K. Filimonov, C. Finley, S. Flis, C.-C. Fösig, A. Franckowiak, E. Friedman, T. Fuchs, T. K. Gaisser, J. Gallagher, L. Gerhardt, K. Ghorbani, W. Giang, L. Gladstone, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, C. Haack, A. Hallgren, F. Halzen, E. Hansen, T. Hansmann, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, S. In, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, W. Kang, A. Kappes, T. Karg, A. Karle, U. Katz, M. Kauer, A. Keivani, J. L. Kelley, A. Kheirandish, J. Kim, M. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, G. Kohnen, R. Koirala, H. Kolanoski, R. Konietz, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, M. Kowalski, K. Krings, M. Kroll, G. Krückl, C. Krüger, J. Kunnen, S. Kunwar, N. Kurahashi, T. Kuwabara, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, D. Lennarz, M. Lesiak-Bzdak, M. Leuermann, L. Lu, J. Lünemann, J. Madsen, G. Maggi, K. B. M. Mahn, S. Mancina, M. Mandelartz, R. Maruyama, K. Mase, R. Maunu, F. McNally, K. Meagher, M. Medici, M. Meier, A. Meli, T. Menne, G. Merino, T. Meures, S. Miarecki, T. Montaruli, M. Moulai, R. Nahnhauer, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, T. Palczewski, H. Pandya, D. V. Pankova, P. Peiffer, Ö. Penek, J. A. Pepper, C. Pérez de los Heros, D. Pieloth, E. Pinat, P. B. Price, G. T. Przybylski, M. Quinnan, C. Raab, L. Rädel, M. Rameez, K. Rawlins, R. Reimann, B. Relethford, M. Relich, E. Resconi, W. Rhode, M. Richman, B. Riedel, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, L. Sabbatini, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, S. Sarkar, K. Satalecka, P. Schlunder, T. Schmidt, S. Schoenen, S. Schöneberg, L. Schumacher, D. Seckel, S. Seunarine, D. Soldin, M. Song, G. M. Spiczak, C. Spiering, T. Stanev, A. Stasik, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, R. Ström, N. L. Strotjohann, G. W. Sullivan, M. Sutherland, H. Taavola, I. Taboada, J. Tatar, F. Tenholt, S. Ter-Antonyan, A. Terliuk, G. Tešić, S. Tilav, P. A. Toale, M. N. Tobin, S. Toscano, D. Tosi, M. Tselengidou, A. Turcati, E. Unger, M. Usner, J. Vandenbroucke, N. van Eijndhoven, S. Vanheule, M. van Rossem, J. van Santen, M. Vehring, M. Voge, E. Vogel, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, N. Wandkowsky, Ch. Weaver, M. J. Weiss, C. Wendt, S. Westerhoff, B. J. Whelan, S. Wickmann, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, T. R. Wood, E. Woolsey, K. Woschnagg, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, and M. Zoll

Subjects
Astrophysics, QB460-466, Nuclear and particle physics. Atomic energy. Radioactivity, QC770-798
Abstract

Abstract We present results from an analysis looking for dark matter annihilation in the Sun with the IceCube neutrino telescope. Gravitationally trapped dark matter in the Sun’s core can annihilate into Standard Model particles making the Sun a source of GeV neutrinos. IceCube is able to detect neutrinos with energies >100 GeV while its low-energy infill array DeepCore extends this to >10 GeV. This analysis uses data gathered in the austral winters between May 2011 and May 2014, corresponding to 532 days of livetime when the Sun, being below the horizon, is a source of up-going neutrino events, easiest to discriminate against the dominant background of atmospheric muons. The sensitivity is a factor of two to four better than previous searches due to additional statistics and improved analysis methods involving better background rejection and reconstructions. The resultant upper limits on the spin-dependent dark matter-proton scattering cross section reach down to $$1.46\times 10^{-5}$$ 1.46×10-5 pb for a dark matter particle of mass 500 GeV annihilating exclusively into $$\tau ^{+}\tau ^{-}$$ τ+τ- particles. These are currently the most stringent limits on the spin-dependent dark matter-proton scattering cross section for WIMP masses above 50 GeV.

Published
2017
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9. Search for Multimessenger Sources of Gravitational Waves and High-energy Neutrinos with Advanced LIGO during Its First Observing Run, ANTARES, and IceCube

Author

A. Albert, M. André, M. Anghinolfi, M. Ardid, J.-J. Aubert, J. Aublin, T. Avgitas, B. Baret, J. Barrios-Martí, S. Basa, B. Belhorma, V. Bertin, S. Biagi, R. Bormuth, J. Boumaaza, S. Bourret, M. C. Bouwhuis, H. Brânzaş, R. Bruijn, J. Brunner, J. Busto, A. Capone, L. Caramete, J. Carr, S. Celli, M. Chabab, R. Cherkaoui El Moursli, T. Chiarusi, M. Circella, J. A. B. Coelho, A. Coleiro, M. Colomer, R. Coniglione, H. Costantini, P. Coyle, A. Creusot, A. F. Díaz, A. Deschamps, C. Distefano, I. Di Palma, A. Domi, R. Donà, C. Donzaud, D. Dornic, D. Drouhin, T. Eberl, I. El Bojaddaini, N. El Khayati, D. Elsässer, A. Enzenhöfer, A. Ettahiri, F. Fassi, I. Felis, P. Fermani, G. Ferrara, L. Fusco, P. Gay, H. Glotin, T. Grégoire, R. Gracia Ruiz, K. Graf, S. Hallmann, H. van Haren, A. J. Heijboer, Y. Hello, J. J. Hernández-Rey, J. Hößl, J. Hofestädt, G. Illuminati, M. de Jong, M. Jongen, M. Kadler, O. Kalekin, U. Katz, N. R. Khan-Chowdhury, A. Kouchner, M. Kreter, I. Kreykenbohm, V. Kulikovskiy, C. Lachaud, R. Lahmann, D. Lefèvre, E. Leonora, G. Levi, M. Lotze, S. Loucatos, G. Maggi, M. Marcelin, A. Margiotta, A. Marinelli, J. A. Martínez-Mora, R. Mele, K. Melis, P. Migliozzi, A. Moussa, S. Navas, E. Nezri, A. Nuñez, M. Organokov, G. E. Păvălaş, C. Pellegrino, P. Piattelli, V. Popa, T. Pradier, L. Quinn, C. Racca, N. Randazzo, G. Riccobene, A. Sánchez-Losa, M. Saldaña, I. Salvadori, D. F. E. Samtleben, M. Sanguineti, P. Sapienza, F. Schüssler, M. Spurio, Th. Stolarczyk, M. Taiuti, Y. Tayalati, A. Trovato, B. Vallage, V. Van Elewyck, F. Versari, D. Vivolo, J. Wilms, D. Zaborov, J. D. Zornoza, J. Zúñiga, ANTARES collaboration, M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, D. Altmann, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, J. Auffenberg, S. Axani, P. Backes, H. Bagherpour, X. Bai, A. Barbano, J. P. Barron, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, J. Becker Tjus, K.-H. Becker, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, F. Bos, S. Böser, O. Botner, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, M. Brenzke, H.-P. Bretz, S. Bron, J. Brostean-Kaiser, A. Burgman, R. S. Busse, T. Carver, E. Cheung, D. Chirkin, K. Clark, L. Classen, G. H. Collin, J. M. Conrad, P. Coppin, P. Correa, D. F. Cowen, R. Cross, P. Dave, M. Day, J. P. A. M. de André, C. De Clercq, J. J. DeLaunay, H. Dembinski, K. Deoskar, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, J. C. Díaz-Vélez, V. di Lorenzo, H. Dujmovic, J. P. Dumm, M. Dunkman, E. Dvorak, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, P. A. Evenson, S. Fahey, A. R. Fazely, J. Felde, K. Filimonov, C. Finley, A. Franckowiak, E. Friedman, A. Fritz, T. K. Gaisser, J. Gallagher, E. Ganster, S. Garrappa, L. Gerhardt, K. Ghorbani, W. Giang, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, C. Haack, A. Hallgren, L. Halve, F. Halzen, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, P. Kalaczynski, W. Kang, A. Kappes, D. Kappesser, T. Karg, A. Karle, M. Kauer, A. Keivani, J. L. Kelley, A. Kheirandish, J. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, J. P. Koschinsky, D. J. Koskinen, M. Kowalski, K. Krings, M. Kroll, G. Krückl, S. Kunwar, N. Kurahashi, A. Kyriacou, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, K. Leonard, M. Leuermann, Q. R. Liu, E. Lohfink, C. J. Lozano Mariscal, L. Lu, J. Lünemann, W. Luszczak, J. Madsen, K. B. M. Mahn, Y. Makino, S. Mancina, I. C. Mariş, R. Maruyama, K. Mase, R. Maunu, K. Meagher, M. Medici, M. Meier, T. Menne, G. Merino, T. Meures, S. Miarecki, J. Micallef, G. Momenté, T. Montaruli, R. W. Moore, M. Moulai, R. Nagai, R. Nahnhauer, P. Nakarmi, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, E. O’Sullivan, T. Palczewski, H. Pandya, D. V. Pankova, P. Peiffer, J. A. Pepper, C. Pérez de los Heros, D. Pieloth, E. Pinat, A. Pizzuto, M. Plum, P. B. Price, G. T. Przybylski, C. Raab, M. Rameez, L. Rauch, K. Rawlins, I. C. Rea, R. Reimann, B. Relethford, G. Renzi, E. Resconi, W. Rhode, M. Richman, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, I. Safa, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Schaufel, P. Schlunder, T. Schmidt, A. Schneider, J. Schneider, S. Schöneberg, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, J. Soedingrekso, D. Soldin, M. Song, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, A. Stasik, R. Stein, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, N. L. Strotjohann, T. Stuttard, G. W. Sullivan, M. Sutherland, I. Taboada, F. Tenholt, S. Ter-Antonyan, A. Terliuk, S. Tilav, P. A. Toale, M. N. Tobin, C. Tönnis, S. Toscano, D. Tosi, M. Tselengidou, C. F. Tung, A. Turcati, R. Turcotte, C. F. Turley, B. Ty, E. Unger, M. A. Unland Elorrieta, M. Usner, J. Vandenbroucke, W. Van Driessche, D. van Eijk, N. van Eijndhoven, S. Vanheule, J. van Santen, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, F. D. Wandler, N. Wandkowsky, T. B. Watson, A. Waza, C. Weaver, M. J. Weiss, C. Wendt, J. Werthebach, S. Westerhoff, B. J. Whelan, N. Whitehorn, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, J. Wood, T. R. Wood, E. Woolsey, K. Woschnagg, G. Wrede, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, T. Yuan, IceCube Collaboration, B. P. Abbott, R. Abbott, T. D. Abbott, S. Abraham, F. Acernese, K. Ackley, C. Adams, V. B. Adya, C. Affeldt, M. Agathos, K. Agatsuma, N. Aggarwal, O. D. Aguiar, L. Aiello, A. Ain, P. Ajith, G. Allen, A. Allocca, M. A. Aloy, P. A. Altin, A. Amato, A. Ananyeva, S. B. Anderson, W. G. Anderson, S. V. Angelova, S. Antier, S. Appert, K. Arai, M. C. Araya, J. S. Areeda, M. Arène, N. Arnaud, K. G. Arun, S. Ascenzi, G. Ashton, S. M. Aston, P. Astone, F. Aubin, P. Aufmuth, K. AultONeal, C. Austin, V. Avendano, A. Avila-Alvarez, S. Babak, P. Bacon, F. Badaracco, M. K. M. Bader, S. Bae, P. T. Baker, F. Baldaccini, G. Ballardin, S. W. Ballmer, S. Banagiri, J. C. Barayoga, S. E. Barclay, B. C. Barish, D. Barker, K. Barkett, S. Barnum, F. Barone, B. Barr, L. Barsotti, M. Barsuglia, D. Barta, J. Bartlett, I. Bartos, R. Bassiri, A. Basti, M. Bawaj, J. C. Bayley, M. Bazzan, B. Bécsy, M. Bejger, I. Belahcene, A. S. Bell, D. Beniwal, B. K. Berger, G. Bergmann, S. Bernuzzi, J. J. Bero, C. P. L. Berry, D. Bersanetti, A. Bertolini, J. Betzwieser, R. Bhandare, J. Bidler, I. A. Bilenko, S. A. Bilgili, G. Billingsley, J. Birch, I. A. Birney, O. Birnholtz, S. Biscans, S. Biscoveanu, A. Bisht, M. Bitossi, M. A. Bizouard, J. K. Blackburn, C. D. Blair, D. G. Blair, R. M. Blair, S. Bloemen, N. Bode, M. Boer, Y. Boetzel, G. Bogaert, F. Bondu, E. Bonilla, R. Bonnand, P. Booker, B. A. Boom, C. D. Booth, R. Bork, V. Boschi, S. Bose, K. Bossie, V. Bossilkov, J. Bosveld, Y. Bouffanais, A. Bozzi, C. Bradaschia, P. R. Brady, A. Bramley, M. Branchesi, J. E. Brau, T. Briant, J. H. Briggs, F. Brighenti, A. Brillet, M. Brinkmann, V. Brisson, P. Brockill, A. F. Brooks, D. D. Brown, S. Brunett, A. Buikema, T. Bulik, H. J. Bulten, A. Buonanno, D. Buskulic, C. Buy, R. L. Byer, M. Cabero, L. Cadonati, G. Cagnoli, C. Cahillane, J. Calderón Bustillo, T. A. Callister, E. Calloni, J. B. Camp, W. A. Campbell, K. C. Cannon, H. Cao, J. Cao, E. Capocasa, F. Carbognani, S. Caride, M. F. Carney, G. Carullo, J. Casanueva Diaz, C. Casentini, S. Caudill, M. Cavaglià, F. Cavalier, R. Cavalieri, G. Cella, P. Cerdá-Durán, G. Cerretani, E. Cesarini, O. Chaibi, K. Chakravarti, S. J. Chamberlin, M. Chan, S. Chao, P. Charlton, E. A. Chase, E. Chassande-Mottin, D. Chatterjee, M. Chaturvedi, B. D. Cheeseboro, H. Y. Chen, X. Chen, Y. Chen, H.-P. Cheng, C. K. Cheong, H. Y. Chia, A. Chincarini, A. Chiummo, G. Cho, H. S. Cho, M. Cho, N. Christensen, Q. Chu, S. Chua, K. W. Chung, S. Chung, G. Ciani, A. A. Ciobanu, R. Ciolfi, F. Cipriano, A. Cirone, F. Clara, J. A. Clark, P. Clearwater, F. Cleva, C. Cocchieri, E. Coccia, P.-F. Cohadon, D. Cohen, R. Colgan, M. Colleoni, C. G. Collette, C. Collins, L. R. Cominsky, M. Constancio Jr., L. Conti, S. J. Cooper, P. Corban, T. R. Corbitt, I. Cordero-Carrión, K. R. Corley, N. Cornish, A. Corsi, S. Cortese, C. A. Costa, R. Cotesta, M. W. Coughlin, S. B. Coughlin, J.-P. Coulon, S. T. Countryman, P. Couvares, P. B. Covas, E. E. Cowan, D. M. Coward, M. J. Cowart, D. C. Coyne, R. Coyne, J. D. E. Creighton, T. D. Creighton, J. Cripe, M. Croquette, S. G. Crowder, T. J. Cullen, A. Cumming, L. Cunningham, E. Cuoco, T. Dal Canton, G. Dálya, S. L. Danilishin, S. D’Antonio, K. Danzmann, A. Dasgupta, C. F. Da Silva Costa, L. E. H. Datrier, V. Dattilo, I. Dave, M. Davier, D. Davis, E. J. Daw, D. DeBra, M. Deenadayalan, J. Degallaix, M. De Laurentis, S. Deléglise, W. Del Pozzo, L. M. DeMarchi, N. Demos, T. Dent, M. Denys, R. De Pietri, J. Derby, R. De Rosa, C. De Rossi, R. DeSalvo, O. de Varona, S. Dhurandhar, M. C. Díaz, T. Dietrich, L. Di Fiore, M. Di Giovanni, T. Di Girolamo, A. Di Lieto, B. Ding, S. Di Pace, F. Di Renzo, A. Dmitriev, Z. Doctor, F. Donovan, K. L. Dooley, S. Doravari, I. Dorrington, T. P. Downes, M. Drago, J. C. Driggers, Z. Du, J.-G. Ducoin, P. Dupej, S. E. Dwyer, P. J. Easter, T. B. Edo, M. C. Edwards, A. Effler, P. Ehrens, J. Eichholz, S. S. Eikenberry, M. Eisenmann, R. A. Eisenstein, R. C. Essick, H. Estelles, D. Estevez, Z. B. Etienne, T. Etzel, M. Evans, T. M. Evans, V. Fafone, H. Fair, S. Fairhurst, X. Fan, S. Farinon, B. Farr, W. M. Farr, E. J. Fauchon-Jones, M. Favata, M. Fays, M. Fazio, C. Fee, J. Feicht, M. M. Fejer, F. Feng, A. Fernandez-Galiana, I. Ferrante, E. C. Ferreira, T. A. Ferreira, F. Ferrini, F. Fidecaro, I. Fiori, D. Fiorucci, M. Fishbach, R. P. Fisher, J. M. Fishner, M. Fitz-Axen, R. Flaminio, M. Fletcher, E. Flynn, H. Fong, J. A. Font, P. W. F. Forsyth, J.-D. Fournier, S. Frasca, F. Frasconi, Z. Frei, A. Freise, R. Frey, V. Frey, P. Fritschel, V. V. Frolov, P. Fulda, M. Fyffe, H. A. Gabbard, B. U. Gadre, S. M. Gaebel, J. R. Gair, L. Gammaitoni, M. R. Ganija, S. G. Gaonkar, A. Garcia, C. García-Quirós, F. Garufi, B. Gateley, S. Gaudio, G. Gaur, V. Gayathri, G. Gemme, E. Genin, A. Gennai, D. George, J. George, L. Gergely, V. Germain, S. Ghonge, Abhirup Ghosh, Archisman Ghosh, S. Ghosh, B. Giacomazzo, J. A. Giaime, K. D. Giardina, A. Giazotto, K. Gill, G. Giordano, L. Glover, P. Godwin, E. Goetz, R. Goetz, B. Goncharov, G. González, J. M. Gonzalez Castro, A. Gopakumar, M. L. Gorodetsky, S. E. Gossan, M. Gosselin, R. Gouaty, A. Grado, C. Graef, M. Granata, A. Grant, S. Gras, P. Grassia, C. Gray, R. Gray, G. Greco, A. C. Green, R. Green, E. M. Gretarsson, P. Groot, H. Grote, S. Grunewald, P. Gruning, G. M. Guidi, H. K. Gulati, Y. Guo, A. Gupta, M. K. Gupta, E. K. Gustafson, R. Gustafson, L. Haegel, O. Halim, B. R. Hall, E. D. Hall, E. Z. Hamilton, G. Hammond, M. Haney, M. M. Hanke, J. Hanks, C. Hanna, O. A. Hannuksela, J. Hanson, T. Hardwick, K. Haris, J. Harms, G. M. Harry, I. W. Harry, C.-J. Haster, K. Haughian, F. J. Hayes, J. Healy, A. Heidmann, M. C. Heintze, H. Heitmann, P. Hello, G. Hemming, M. Hendry, I. S. Heng, J. Hennig, A. W. Heptonstall, F. J. Hernandez, M. Heurs, S. Hild, T. Hinderer, D. Hoak, S. Hochheim, D. Hofman, A. M. Holgado, N. A. Holland, K. Holt, D. E. Holz, P. Hopkins, C. Horst, J. Hough, E. J. Howell, C. G. Hoy, A. Hreibi, E. A. Huerta, D. Huet, B. Hughey, M. Hulko, S. Husa, S. H. Huttner, T. Huynh-Dinh, B. Idzkowski, A. Iess, C. Ingram, R. Inta, G. Intini, B. Irwin, H. N. Isa, J.-M. Isac, M. Isi, B. R. Iyer, K. Izumi, T. Jacqmin, S. J. Jadhav, K. Jani, N. N. Janthalur, P. Jaranowski, A. C. Jenkins, J. Jiang, D. S. Johnson, A. W. Jones, D. I. Jones, R. Jones, R. J. G. Jonker, L. Ju, J. Junker, C. V. Kalaghatgi, V. Kalogera, B. Kamai, S. Kandhasamy, G. Kang, J. B. Kanner, S. J. Kapadia, S. Karki, K. S. Karvinen, R. Kashyap, M. Kasprzack, S. Katsanevas, E. Katsavounidis, W. Katzman, S. Kaufer, K. Kawabe, N. V. Keerthana, F. Kéfélian, D. Keitel, R. Kennedy, J. S. Key, F. Y. Khalili, H. Khan, I. Khan, S. Khan, Z. Khan, E. A. Khazanov, M. Khursheed, N. Kijbunchoo, Chunglee Kim, J. C. Kim, K. Kim, W. Kim, W. S. Kim, Y.-M. Kim, C. Kimball, E. J. King, P. J. King, M. Kinley-Hanlon, R. Kirchhoff, J. S. Kissel, L. Kleybolte, J. H. Klika, S. Klimenko, T. D. Knowles, P. Koch, S. M. Koehlenbeck, G. Koekoek, S. Koley, V. Kondrashov, A. Kontos, N. Koper, M. Korobko, W. Z. Korth, I. Kowalska, D. B. Kozak, V. Kringel, N. Krishnendu, A. Królak, G. Kuehn, A. Kumar, P. Kumar, R. Kumar, S. Kumar, L. Kuo, A. Kutynia, S. Kwang, B. D. Lackey, K. H. Lai, T. L. Lam, M. Landry, B. B. Lane, R. N. Lang, J. Lange, B. Lantz, R. K. Lanza, A. Lartaux-Vollard, P. D. Lasky, M. Laxen, A. Lazzarini, C. Lazzaro, P. Leaci, S. Leavey, Y. K. Lecoeuche, C. H. Lee, H. K. Lee, H. M. Lee, H. W. Lee, J. Lee, K. Lee, J. Lehmann, A. Lenon, N. Leroy, N. Letendre, Y. Levin, J. Li, K. J. L. Li, T. G. F. Li, X. Li, F. Lin, F. Linde, S. D. Linker, T. B. Littenberg, J. Liu, X. Liu, R. K. L. Lo, N. A. Lockerbie, L. T. London, A. Longo, M. Lorenzini, V. Loriette, M. Lormand, G. Losurdo, J. D. Lough, C. O. Lousto, G. Lovelace, M. E. Lower, H. Lück, D. Lumaca, A. P. Lundgren, R. Lynch, Y. Ma, R. Macas, S. Macfoy, M. MacInnis, D. M. Macleod, A. Macquet, F. Magaña-Sandoval, L. Magaña Zertuche, R. M. Magee, E. Majorana, I. Maksimovic, A. Malik, N. Man, V. Mandic, V. Mangano, G. L. Mansell, M. Manske, M. Mantovani, F. Marchesoni, F. Marion, S. Márka, Z. Márka, C. Markakis, A. S. Markosyan, A. Markowitz, E. Maros, A. Marquina, S. Marsat, F. Martelli, I. W. Martin, R. M. Martin, D. V. Martynov, K. Mason, E. Massera, A. Masserot, T. J. Massinger, M. Masso-Reid, S. Mastrogiovanni, A. Matas, F. Matichard, L. Matone, N. Mavalvala, N. Mazumder, J. J. McCann, R. McCarthy, D. E. McClelland, S. McCormick, L. McCuller, S. C. McGuire, J. McIver, D. J. McManus, T. McRae, S. T. McWilliams, D. Meacher, G. D. Meadors, M. Mehmet, A. K. Mehta, J. Meidam, A. Melatos, G. Mendell, R. A. Mercer, L. Mereni, E. L. Merilh, M. Merzougui, S. Meshkov, C. Messenger, C. Messick, R. Metzdorff, P. M. Meyers, H. Miao, C. Michel, H. Middleton, E. E. Mikhailov, L. Milano, A. L. Miller, A. Miller, M. Millhouse, J. C. Mills, M. C. Milovich-Goff, O. Minazzoli, Y. Minenkov, A. Mishkin, C. Mishra, T. Mistry, S. Mitra, V. P. Mitrofanov, G. Mitselmakher, R. Mittleman, G. Mo, D. Moffa, K. Mogushi, S. R. P. Mohapatra, M. Montani, C. J. Moore, D. Moraru, G. Moreno, S. Morisaki, B. Mours, C. M. Mow-Lowry, Arunava Mukherjee, D. Mukherjee, S. Mukherjee, N. Mukund, A. Mullavey, J. Munch, E. A. Muñiz, M. Muratore, P. G. Murray, I. Nardecchia, L. Naticchioni, R. K. Nayak, J. Neilson, G. Nelemans, T. J. N. Nelson, M. Nery, A. Neunzert, K. Y. Ng, S. Ng, P. Nguyen, D. Nichols, S. Nissanke, F. Nocera, C. North, L. K. Nuttall, M. Obergaulinger, J. Oberling, B. D. O’Brien, G. D. O’Dea, G. H. Ogin, J. J. Oh, S. H. Oh, F. Ohme, H. Ohta, M. A. Okada, M. Oliver, P. Oppermann, Richard J. Oram, B. O’Reilly, R. G. Ormiston, L. F. Ortega, R. O’Shaughnessy, S. Ossokine, D. J. Ottaway, H. Overmier, B. J. Owen, A. E. Pace, G. Pagano, M. A. Page, A. Pai, S. A. Pai, J. R. Palamos, O. Palashov, C. Palomba, A. Pal-Singh, Huang-Wei Pan, B. Pang, P. T. H. Pang, C. Pankow, F. Pannarale, B. C. Pant, F. Paoletti, A. Paoli, A. Parida, W. Parker, D. Pascucci, A. Pasqualetti, R. Passaquieti, D. Passuello, M. Patil, B. Patricelli, B. L. Pearlstone, C. Pedersen, M. Pedraza, R. Pedurand, A. Pele, S. Penn, C. J. Perez, A. Perreca, H. P. Pfeiffer, M. Phelps, K. S. Phukon, O. J. Piccinni, M. Pichot, F. Piergiovanni, G. Pillant, L. Pinard, M. Pirello, M. Pitkin, R. Poggiani, D. Y. T. Pong, S. Ponrathnam, P. Popolizio, E. K. Porter, J. Powell, A. K. Prajapati, J. Prasad, K. Prasai, R. Prasanna, G. Pratten, T. Prestegard, S. Privitera, G. A. Prodi, L. G. Prokhorov, O. Puncken, M. Punturo, P. Puppo, M. Pürrer, H. Qi, V. Quetschke, P. J. Quinonez, E. A. Quintero, R. Quitzow-James, F. J. Raab, H. Radkins, N. Radulescu, P. Raffai, S. Raja, C. Rajan, B. Rajbhandari, M. Rakhmanov, K. E. Ramirez, A. Ramos-Buades, Javed Rana, K. Rao, P. Rapagnani, V. Raymond, M. Razzano, J. Read, T. Regimbau, L. Rei, S. Reid, D. H. Reitze, W. Ren, F. Ricci, C. J. Richardson, J. W. Richardson, P. M. Ricker, K. Riles, M. Rizzo, N. A. Robertson, R. Robie, F. Robinet, A. Rocchi, L. Rolland, J. G. Rollins, V. J. Roma, M. Romanelli, R. Romano, C. L. Romel, J. H. Romie, K. Rose, D. Rosińska, S. G. Rosofsky, M. P. Ross, S. Rowan, A. Rüdiger, P. Ruggi, G. Rutins, K. Ryan, S. Sachdev, T. Sadecki, M. Sakellariadou, L. Salconi, M. Saleem, A. Samajdar, L. Sammut, E. J. Sanchez, L. E. Sanchez, N. Sanchis-Gual, V. Sandberg, J. R. Sanders, K. A. Santiago, N. Sarin, B. Sassolas, P. R. Saulson, O. Sauter, R. L. Savage, P. Schale, M. Scheel, J. Scheuer, F. Schiettekatte, P. Schmidt, R. Schnabel, R. M. S. Schofield, A. Schönbeck, E. Schreiber, B. W. Schulte, B. F. Schutz, S. G. Schwalbe, J. Scott, S. M. Scott, E. Seidel, D. Sellers, A. S. Sengupta, N. Sennett, D. Sentenac, V. Sequino, A. Sergeev, Y. Setyawati, D. A. Shaddock, T. Shaffer, M. S. Shahriar, M. B. Shaner, L. Shao, P. Sharma, P. Shawhan, H. Shen, R. Shink, D. H. Shoemaker, D. M. Shoemaker, S. ShyamSundar, K. Siellez, M. Sieniawska, D. Sigg, A. D. Silva, L. P. Singer, N. Singh, A. Singhal, A. M. Sintes, S. Sitmukhambetov, V. Skliris, B. J. J. Slagmolen, T. J. Slaven-Blair, J. R. Smith, R. J. E. Smith, S. Somala, E. J. Son, B. Sorazu, F. Sorrentino, T. Souradeep, E. Sowell, A. P. Spencer, A. K. Srivastava, V. Srivastava, K. Staats, C. Stachie, M. Standke, D. A. Steer, M. Steinke, J. Steinlechner, S. Steinlechner, D. Steinmeyer, S. P. Stevenson, D. Stocks, R. Stone, D. J. Stops, K. A. Strain, G. Stratta, S. E. Strigin, A. Strunk, R. Sturani, A. L. Stuver, V. Sudhir, T. Z. Summerscales, L. Sun, S. Sunil, J. Suresh, P. J. Sutton, B. L. Swinkels, M. J. Szczepańczyk, M. Tacca, S. C. Tait, C. Talbot, D. Talukder, D. B. Tanner, M. Tápai, A. Taracchini, J. D. Tasson, R. Taylor, F. Thies, M. Thomas, P. Thomas, S. R. Thondapu, K. A. Thorne, E. Thrane, Shubhanshu Tiwari, Srishti Tiwari, V. Tiwari, K. Toland, M. Tonelli, Z. Tornasi, A. Torres-Forné, C. I. Torrie, D. Töyrä, F. Travasso, G. Traylor, M. C. Tringali, L. Trozzo, R. Trudeau, K. W. Tsang, M. Tse, R. Tso, L. Tsukada, D. Tsuna, D. Tuyenbayev, K. Ueno, D. Ugolini, C. S. Unnikrishnan, A. L. Urban, S. A. Usman, H. Vahlbruch, G. Vajente, G. Valdes, N. van Bakel, M. van Beuzekom, J. F. J. van den Brand, C. Van Den Broeck, D. C. Vander-Hyde, L. van der Schaaf, J. V. van Heijningen, A. A. van Veggel, M. Vardaro, V. Varma, S. Vass, M. Vasúth, A. Vecchio, G. Vedovato, J. Veitch, P. J. Veitch, K. Venkateswara, G. Venugopalan, D. Verkindt, F. Vetrano, A. Viceré, A. D. Viets, D. J. Vine, J.-Y. Vinet, S. Vitale, T. Vo, H. Vocca, C. Vorvick, S. P. Vyatchanin, A. R. Wade, L. E. Wade, M. Wade, R. Walet, M. Walker, L. Wallace, S. Walsh, G. Wang, H. Wang, J. Z. Wang, W. H. Wang, Y. F. Wang, R. L. Ward, Z. A. Warden, J. Warner, M. Was, J. Watchi, B. Weaver, L.-W. Wei, M. Weinert, A. J. Weinstein, R. Weiss, F. Wellmann, L. Wen, E. K. Wessel, P. Weßels, J. W. Westhouse, K. Wette, J. T. Whelan, B. F. Whiting, C. Whittle, D. M. Wilken, D. Williams, A. R. Williamson, J. L. Willis, B. Willke, M. H. Wimmer, W. Winkler, C. C. Wipf, H. Wittel, G. Woan, J. Woehler, J. K. Wofford, J. Worden, J. L. Wright, D. S. Wu, D. M. Wysocki, L. Xiao, H. Yamamoto, C. C. Yancey, L. Yang, M. J. Yap, M. Yazback, D. W. Yeeles, Hang Yu, Haocun Yu, S. H. R. Yuen, M. Yvert, A. K. Zadrozny, A. Zadrożny, M. Zanolin, T. Zelenova, J.-P. Zendri, M. Zevin, J. Zhang, L. Zhang, T. Zhang, C. Zhao, M. Zhou, Z. Zhou, X. J. Zhu, M. E. Zucker, J. Zweizig, and The LIGO Scientific Collaboration and the Virgo Collaboration

Subjects
gravitational waves, neutrinos, Astrophysics, QB460-466
Abstract

Astrophysical sources of gravitational waves, such as binary neutron star and black hole mergers or core-collapse supernovae, can drive relativistic outflows, giving rise to non-thermal high-energy emission. High-energy neutrinos are signatures of such outflows. The detection of gravitational waves and high-energy neutrinos from common sources could help establish the connection between the dynamics of the progenitor and the properties of the outflow. We searched for associated emission of gravitational waves and high-energy neutrinos from astrophysical transients with minimal assumptions using data from Advanced LIGO from its first observing run O1, and data from the A ntares and IceCube neutrino observatories from the same time period. We focused on candidate events whose astrophysical origins could not be determined from a single messenger. We found no significant coincident candidate, which we used to constrain the rate density of astrophysical sources dependent on their gravitational-wave and neutrino emission processes.

Published
2019
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10. Five versus seven days of nitrofurantoin for urinary tract infections in women with diabetes: a retrospective cohort study

Author

Theo J M Verheij, Cornelis H. van Werkhoven, Kelly D. Hendriks-Spoor, Thijs ten Doesschate, Julia W. Dorigo-Zetsma, and Floor L. Wille

Subjects
Microbiology (medical), medicine.medical_specialty, business.industry, Urinary system, Significant difference, Anti-Infective Agents, Urinary, Retrospective cohort study, General Medicine, medicine.disease, Treatment failure, Infectious Diseases, Risk groups, Nitrofurantoin, Diabetes mellitus, Internal medicine, Urinary Tract Infections, Diabetes Mellitus, Humans, Medicine, Female, Medical prescription, business, Retrospective Studies, medicine.drug
Abstract

Objective To compare the effectiveness of five versus seven days of nitrofurantoin treatment for urinary tract infection (UTI) in diabetic women. Methods Data were collected retrospectively from Dutch general practitioners between 2013 and 2020. Nitrofurantoin prescriptions with a duration of five (5DN) or seven days (7DN) in women with diabetes were included. Inverse propensity weighting (IPW) was performed to calculate adjusted risk differences (RD) for treatment failure within 28 days. Secondary outcomes were 14-day treatment failure, severe treatment failure, and 28-day treatment failure in defined risk groups. Results Nitrofurantoin was prescribed in 6866 episodes, 3247 (47,3%) episodes with 5DN and 3619 (52,7%) episodes with 7DN. Patients in the 7DN group had more co-morbidities, more diabetes-related complications and were more insulin-dependent. There were 517/3247 (15.9%) failures in the 5DN group versus 520/3619 (14.4%) in the 7DN group. The adjusted RD for failure within 28 days was 1.4% (95% CI -0.6 to 3.4). Conclusion We found no clinically significant difference in treatment failure in diabetic women with UTI treated either five or seven days with nitrofurantoin within 28 days. A 5-day treatment should be considered to reduce cumulative nitrofurantoin exposure in DM patients.

Published
2022

12. IceCube Search for High-Energy Neutrino Emission from TeV Pulsar Wind Nebulae

Author

C. Haack, Immacolata Carmen Rea, Emily Dvorak, K.-H. Becker, K. Hoshina, Yiqian Xu, Matt Dunkman, K. Mase, Yuya Makino, Minjin Jeong, Timothyblake Watson, Thomas Meures, B. Relethford, E. Cheung, Saskia Philippen, M. J. Weiss, Konstancja Satalecka, Theo Glauch, L. Rauch, U. Katz, Thomas Stuttard, S. De Ridder, Jeffrey Lazar, P. B. Price, D. Heereman, S. Yoshida, D. B. Fox, S. Kopper, Sarah Pieper, K. Jero, N. L. Strotjohann, Hermann Kolanoski, Dirk Ryckbosch, Stef Verpoest, Colin Turley, Felix Henningsen, M. Zöcklein, René Reimann, C. Alispach, Lenka Tomankova, T. Grégoire, Timo Karg, A. Steuer, Stephan Meighen-Berger, Janet Conrad, Thomas Ehrhardt, Frank G. Schröder, A. R. Fazely, M. Silva, Francesco Lucarelli, Raamis Hussain, R. Cross, A. Obertacke Pollmann, E. Pinat, T. O. B. Schmidt, Johannes Werthebach, M. Usner, Kael Hanson, Karl J. Clark, Maximilian Meier, S. Hickford, R. Joppe, Delia Tosi, Sebastian Baur, Chujie Chen, A. Weindl, Maryon Ahrens, Frederik Tenholt, R. Nagai, K. Helbing, Won Nam Kang, X. Bai, G. Neer, Simona Toscano, P. Heix, R. Maunu, J. Lünemann, William Luszczak, S. Tilav, M. Medici, Christian Spiering, L. Wills, P. Muth, P. Schlunder, Daria Pankova, E. Friedman, R. S. Busse, M. Song, T. L. Carver, Mike Richman, Amirreza Raissi, Federica Bradascio, Alexander Burgman, T. R. Wood, Ramesh Koirala, J. P. Yanez, Karim Ghorbani, Spencer Axani, Christopher Wiebusch, Kunal Deoskar, Paolo Desiati, Chris Weaver, Stephanie Bron, Kurt Woschnagg, C. J. Lozano Mariscal, G. Merino, Tim Ruhe, Justin Vandenbroucke, H. Bagherpour, Alexander Sandrock, J. L. Kelley, Markus Ahlers, Martin Rongen, George Japaridze, Roger Moore, A. Ludwig, Olga Botner, Paul Evenson, M. G. Aartsen, N. Wandkowsky, H. Dujmovic, Merlin Schaufel, M. Stamatikos, E. Blaufuss, Ioana Codrina Maris, L. Wille, H. Niederhausen, Carlos Arguelles, Ibrahim Safa, V. Baum, Jessie Micallef, L. Classen, Damian Pieloth, Ali Kheirandish, N. Kurahashi, J. Bourbeau, D. Kang, Todor Stanev, K. Tollefson, Surujhdeo Seunarine, Albrecht Karle, D. van Eijk, Christoph Raab, Nadège Iovine, P. Mallik, Simone Garrappa, Dmitry Chirkin, S. C. Nowicki, W. Van Driessche, C. Wendt, Alexander Kappes, Erik Ganster, K. Mallot, R. Morse, James W. Wood, Z. Griffith, Jakob Bottcher, D. Berley, G. C. Hill, Bunheng Ty, R. Snihur, T. Montaruli, Jannes Brostean-Kaiser, Juanan Aguilar, G. de Wasseige, G. W. Sullivan, K. Rawlins, Donglian Xu, Seongjin In, B. J. P. Jones, Ralph Engel, Moritz Kellermann, Elisa Resconi, I. Taboada, Samvel Ter-Antonyan, Elisa Lohfink, James E. Braun, Gisela Anton, James Madsen, Lu Lu, Alessio Porcelli, T. Kintscher, Frederik Hermann Lauber, Giovanni Renzi, A. Goldschmidt, D. Hebecker, Qinrui Liu, R. Hoffmann, T. Glüsenkamp, Le Viet Nguyen, L. Köpke, D. Seckel, S. Fahey, Michael O. Wolf, Alexander Fritz, D. Z. Besson, Martina Karl, A. Wallace, A. Terliuk, Paul Coppin, Andrea Turcati, Justin Lanfranchi, J. van Santen, Mehr Nisa, Jochen M. Schneider, B. J. Whelan, Claudio Kopper, A. Ishihara, Tyce DeYoung, Andres Medina, Alexander Trettin, Nathan Whitehorn, Alex Pizzuto, D. R. Nygren, Gerald Przybylski, S. E. Sanchez Herrera, M. A. Unland Elorrieta, Gary Binder, R. Halliday, A. Haungs, C. Pérez de los Heros, K. Krings, D. Mockler, Nahee Park, K. Hultqvist, M. Wallraff, Darren Grant, Kendall Mahn, C. Walck, Alan Coleman, E. O’Sullivan, T. Anderson, Marek Kowalski, J. C. Gallagher, M. Plum, Subir Sarkar, Jan Weldert, Thomas K. Gaisser, G. B. Yodh, A. Kyriacou, Gerrit Wrede, K. Meagher, L. Halve, Philipp Eller, Thomas Huber, Allan Hallgren, Benjamin Hokanson-Fasig, Yang Lyu, Elisa Bernardini, J. Auffenberg, Chunfai Tung, J. Becker Tjus, J. Felde, J. Buscher, D. Rysewyk Cantu, Jenni Adams, P. Peiffer, Joshua Hignight, Timo Sturwald, H. Schieler, Kirill Filimonov, K. Wiebe, Steven Robertson, R. G. Stokstad, Segev BenZvi, Shefali Shefali, Spencer Klein, Abdul Rehman, Carsten Rott, Kara Hoffman, Javier Gonzalez, Roxanne Turcotte, Giorgio Maggi, Matthias Vraeghe, C. De Clercq, Hershal Pandya, Wolfgang Rhode, David A. Williams, Xianwu Xu, Robert Stein, J. Sandroos, Markus Ackermann, S. W. Barwick, C. Bohm, J. Kim, Daniel Bindig, K. D. de Vries, N. Kulacz, Brian Clark, Chad Finley, Christoph Tönnis, Pranav Dave, M. Günder, T. Stezelberger, G. H. Collin, Sarah Mancina, Anna Franckowiak, Tobias Hoinka, Kayla Leonard, Steve Sclafani, Jan Soedingrekso, Francis Halzen, J. Kiryluk, K. Andeen, I. Ansseau, G. Krückl, Juliana Stachurska, Alejandro Diaz, Pablo Correa, H. Dembinski, M. Kauer, Suyong Choi, David Kappesser, R. Hellauer, Matti Jansson, T. Palczewski, Sebastian Böser, Benjamin Bastian, Anastasia Maria Barbano, T. Kittler, B. Eberhardt, M. E. Huber, Marcos Santander, L. Gerhardt, A. Olivas, M. J. Larson, Wing Yan Ma, James DeLaunay, Marjon Moulai, J. J. Beatty, Tianlu Yuan, F. McNally, A. Stößl, Reina H. Maruyama, Summer Blot, F. Jonske, L. Schumacher, F. Huang, Mehmet Gunduz, Agnieszka Leszczyńska, R. C. Bay, Austin Schneider, Juan Carlos Diaz-Velez, Glenn Spiczak, G. Momenté, M. Rameez, D. F. Cowen, U. Naumann, E. Unger, A. O'Murchadha, Max Renschler, D. J. Koskinen, E. Bourbeau, Spencer Griswold, Maria Tselengidou, D. Soldin, J. Stettner, Mirco Hunnefeld, Marie Oehler, N. van Eijndhoven, Physics, Faculty of Sciences and Bioengineering Sciences, Vriendenkring VUB, and Elementary Particle Physics

Subjects
010504 meteorology & atmospheric sciences, High-energy astronomy, Astrophysics::High Energy Astrophysical Phenomena, Neutrino astronomy, High energy astrophysics, FOS: Physical sciences, Cosmic ray, Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, 01 natural sciences, 7. Clean energy, Pulsar, 0103 physical sciences, 010303 astronomy & astrophysics, Astrophysics::Galaxy Astrophysics, 0105 earth and related environmental sciences, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), astro-ph.HE, Astronomy and Astrophysics, Galactic plane, COSMIC-RAYS, CRAB-NEBULA, Crab Nebula, Physics and Astronomy, 13. Climate action, Space and Planetary Science, GALACTIC SOURCES, DISCOVERY, Physique des particules élémentaires, High Energy Physics::Experiment, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, GAMMA-RAY EMISSION, Lepton
Abstract

Pulsar wind nebulae (PWNe) are the main gamma-ray emitters in the Galactic plane. They are diffuse nebulae that emit nonthermal radiation. Pulsar winds, relativistic magnetized outflows from the central star, shocked in the ambient medium produce a multiwavelength emission from the radio through gamma-rays. Although the leptonic scenario is able to explain most PWNe emission, a hadronic contribution cannot be excluded. A possible hadronic contribution to the high-energy gamma-ray emission inevitably leads to the production of neutrinos. Using 9.5 yr of all-sky IceCube data, we report results from a stacking analysis to search for neutrino emission from 35 PWNe that are high-energy gamma-ray emitters. In the absence of any significant correlation, we set upper limits on the total neutrino emission from those PWNe and constraints on hadronic spectral components., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2020

13. In-situ calibration of the single-photoelectron charge response of the IceCube photomultiplier tubes

Author

M.G. Aartsen, M. Ackermann, J. Adams, J.A. Aguilar, M. Ahlers, M. Ahrens, C. Alispach, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, J. Auffenberg, S. Axani, P. Backes, H. Bagherpour, X. Bai, A. Balagopal V., A. Barbano, S.W. Barwick, B. Bastian, V. Baum, S. Baur, R. Bay, J.J. Beatty, K.-H. Becker, J. Becker Tjus, S. BenZvi, D. Berley, E. Bernardini, D.Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, S. Böser, O. Botner, J. Böttcher, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, S. Bron, J. Brostean-Kaiser, A. Burgman, J. Buscher, R.S. Busse, T. Carver, C. Chen, E. Cheung, D. Chirkin, S. Choi, K. Clark, L. Classen, A. Coleman, G.H. Collin, J.M. Conrad, P. Coppin, P. Correa, D.F. Cowen, R. Cross, P. Dave, C. De Clercq, J.J. DeLaunay, H. Dembinski, K. Deoskar, S. De Ridder, P. Desiati, K.D. de Vries, G. de Wasseige, M. de With, T. DeYoung, A. Diaz, J.C. Díaz-Vélez, H. Dujmovic, M. Dunkman, E. Dvorak, B. Eberhardt, T. Ehrhardt, P. Eller, R. Engel, P.A. Evenson, S. Fahey, A.R. Fazely, J. Felde, K. Filimonov, C. Finley, D. Fox, A. Franckowiak, E. Friedman, A. Fritz, T.K. Gaisser, J. Gallagher, E. Ganster, S. Garrappa, L. Gerhardt, K. Ghorbani, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J.G. Gonzalez, D. Grant, Z. Griffith, S. Griswold, M. Günder, M. Gündüz, C. Haack, A. Hallgren, L. Halve, F. Halzen, K. Hanson, A. Haungs, D. Hebecker, D. Heereman, P. Heix, K. Helbing, R. Hellauer, F. Henningsen, S. Hickford, J. Hignight, G.C. Hill, K.D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, T. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, G.S. Japaridze, M. Jeong, K. Jero, B.J.P. Jones, F. Jonske, R. Joppe, D. Kang, W. Kang, A. Kappes, D. Kappesser, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, J.L. Kelley, A. Kheirandish, J. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S.R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, D.J. Koskinen, M. Kowalski, K. Krings, G. Krückl, N. Kulacz, N. Kurahashi, A. Kyriacou, M. Labare, J.L. Lanfranchi, M.J. Larson, F. Lauber, J.P. Lazar, K. Leonard, A. Leszczyńska, M. Leuermann, Q.R. Liu, E. Lohfink, C.J. Lozano Mariscal, L. Lu, F. Lucarelli, J. Lünemann, W. Luszczak, Y. Lyu, W.Y. Ma, J. Madsen, G. Maggi, K.B.M. Mahn, Y. Makino, P. Mallik, K. Mallot, S. Mancina, I.C. Mariş, R. Maruyama, K. Mase, R. Maunu, F. McNally, K. Meagher, M. Medici, A. Medina, M. Meier, S. Meighen-Berger, T. Menne, G. Merino, T. Meures, J. Micallef, D. Mockler, G. Momenté, T. Montaruli, R.W. Moore, R. Morse, M. Moulai, P. Muth, R. Nagai, U. Naumann, G. Neer, H. Niederhausen, M.U. Nisa, S.C. Nowicki, D.R. Nygren, A. Obertacke Pollmann, M. Oehler, A. Olivas, A. O'Murchadha, E. O'Sullivan, T. Palczewski, H. Pandya, D.V. Pankova, N. Park, P. Peiffer, C. Pérez de los Heros, S. Philippen, D. Pieloth, E. Pinat, A. Pizzuto, M. Plum, A. Porcelli, P.B. Price, G.T. Przybylski, C. Raab, A. Raissi, M. Rameez, L. Rauch, K. Rawlins, I.C. Rea, R. Reimann, B. Relethford, M. Renschler, G. Renzi, E. Resconi, W. Rhode, M. Richman, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, I. Safa, S.E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Schaufel, H. Schieler, P. Schlunder, T. Schmidt, A. Schneider, J. Schneider, F.G. Schröder, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, S. Shefali, M. Silva, R. Snihur, J. Soedingrekso, D. Soldin, M. Song, G.M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, R. Stein, P. Steinmüller, J. Stettner, A. Steuer, T. Stezelberger, R.G. Stokstad, A. Stößl, N.L. Strotjohann, T. Stürwald, T. Stuttard, G.W. Sullivan, I. Taboada, F. Tenholt, S. Ter-Antonyan, A. Terliuk, S. Tilav, K. Tollefson, L. Tomankova, C. Tönnis, S. Toscano, D. Tosi, A. Trettin, M. Tselengidou, C.F. Tung, A. Turcati, R. Turcotte, C.F. Turley, B. Ty, E. Unger, M.A. Unland Elorrieta, M. Usner, J. Vandenbroucke, W. Van Driessche, D. van Eijk, N. van Eijndhoven, S. Vanheule, J. van Santen, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, N. Wandkowsky, T.B. Watson, C. Weaver, A. Weindl, M.J. Weiss, J. Weldert, C. Wendt, J. Werthebach, B.J. Whelan, N. Whitehorn, K. Wiebe, C.H. Wiebusch, L. Wille, D.R. Williams, L. Wills, M. Wolf, J. Wood, T.R. Wood, K. Woschnagg, G. Wrede, D.L. Xu, X.W. Xu, Y. Xu, J.P. Yanez, G. Yodh, S. Yoshida, T. Yuan, M. Zöcklein, Physics, Faculty of Sciences and Bioengineering Sciences, Vriendenkring VUB, and Elementary Particle Physics

Subjects
electron, Physics - Instrumentation and Detectors, Detector modelling and simulations II (electric fields, Physics::Instrumentation and Detectors, Monte Carlo method, 01 natural sciences, charge distribution, 030218 nuclear medicine & medical imaging, IceCube, 0302 clinical medicine, DESIGN, charge, emission, (photomultipliers, Instrumentation, Photon detectors for UV, physics.ins-det, Mathematical Physics, Physics, Detector, Astrophysics::Instrumentation and Methods for Astrophysics, Charge density, calibration [photomultiplier], Monte Carlo [numerical calculations], Instrumentation and Detectors (physics.ins-det), photomultiplier: calibration, Detector modelling and simulations II (electric fields, charge transport, multiplication and induction, pulse formation, electron emission, etc), Neutrino detector, HPDs, Physique des particules élémentaires, Neutrino, numerical calculations: Monte Carlo, others), photoelectron, Photomultiplier, data analysis method, pulse formation, Visible and IR photons (vacuum) (photomultipliers, HPDs, others), FOS: Physical sciences, Particle detector, IceCube Neutrino Observatory, 03 medical and health sciences, Optics, 0103 physical sciences, Physics::Atomic and Molecular Clusters, Visible and IR photons (vacuum) (photomultipliers, ddc:610, etc), multiplication and induction, 010308 nuclear & particles physics, business.industry, PERFORMANCE, visible and IR photons (vacuum), charge transport, Physics and Astronomy, electron emission, transport, business
Abstract

Journal of Instrumentation 15(06), P06032 (2020). doi:10.1088/1748-0221/15/06/P06032, We describe an improved in-situ calibration of the single-photoelectron charge distributions for each of the in-ice Hamamatsu Photonics R7081-02[MOD] photomultiplier tubes in the IceCube Neutrino Observatory. The characterization of the individual PMT charge distributions is important for PMT calibration, data and Monte Carlo simulation agreement, and understanding the effect of hardware differences within the detector. We discuss the single photoelectron identification procedure and how we extract the single-photoelectron charge distribution using a deconvolution of the multiple-photoelectron charge distribution., Published by Inst. of Physics, London

Published
2020

14. Development of an analysis to probe the neutrino mass ordering with atmospheric neutrinos using three years of IceCube DeepCore data IceCube Collaboration

Author

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, C. Alispach, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, J. Auffenberg, S. Axani, P. Backes, H. Bagherpour, X. Bai, A. Barbano, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, K.-H. Becker, J. Becker Tjus, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, S. Böser, O. Botner, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, H.-P. Bretz, S. Bron, J. Brostean-Kaiser, A. Burgman, R. S. Busse, T. Carver, C. Chen, E. Cheung, D. Chirkin, K. Clark, L. Classen, G. H. Collin, J. M. Conrad, P. Coppin, P. Correa, D. F. Cowen, R. Cross, P. Dave, J. P. A. M. de André, C. De Clercq, J. J. DeLaunay, H. Dembinski, K. Deoskar, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, A. Diaz, J. C. Díaz-Vélez, H. Dujmovic, M. Dunkman, E. Dvorak, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, J. J. Evans, P. A. Evenson, S. Fahey, A. R. Fazely, J. Felde, K. Filimonov, C. Finley, A. Franckowiak, E. Friedman, A. Fritz, T. K. Gaisser, J. Gallagher, E. Ganster, S. Garrappa, L. Gerhardt, K. Ghorbani, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, M. Günder, M. Gündüz, C. Haack, A. Hallgren, L. Halve, F. Halzen, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, F. Henningsen, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, W. Kang, A. Kappes, D. Kappesser, T. Karg, M. Karl, A. Karle, U. Katz, M. Kauer, J. L. Kelley, A. Kheirandish, J. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, M. Kowalski, K. Krings, G. Krückl, N. Kulacz, S. Kunwar, N. Kurahashi, A. Kyriacou, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, J. P. Lazar, K. Leonard, M. Leuermann, Q. R. Liu, E. Lohfink, C. J. Lozano Mariscal, L. Lu, F. Lucarelli, J. Lünemann, W. Luszczak, J. Madsen, G. Maggi, K. B. M. Mahn, Y. Makino, K. Mallot, S. Mancina, I. C. Mariş, R. Maruyama, K. Mase, R. Maunu, K. Meagher, M. Medici, A. Medina, M. Meier, S. Meighen-Berger, T. Menne, G. Merino, T. Meures, S. Miarecki, J. Micallef, G. Momenté, T. Montaruli, R. W. Moore, M. Moulai, R. Nagai, R. Nahnhauer, P. Nakarmi, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, E. O’Sullivan, T. Palczewski, H. Pandya, D. V. Pankova, N. Park, P. Peiffer, C. Pérez de los Heros, D. Pieloth, E. Pinat, A. Pizzuto, M. Plum, P. B. Price, G. T. Przybylski, C. Raab, A. Raissi, M. Rameez, L. Rauch, K. Rawlins, I. C. Rea, R. Reimann, B. Relethford, G. Renzi, E. Resconi, W. Rhode, M. Richman, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, I. Safa, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Schaufel, P. Schlunder, T. Schmidt, A. Schneider, J. Schneider, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, M. Silva, R. Snihur, J. Soedingrekso, D. Soldin, S. Söldner-Rembold, M. Song, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, A. Stasik, R. Stein, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, N. L. Strotjohann, T. Stuttard, G. W. Sullivan, M. Sutherland, I. Taboada, F. Tenholt, S. Ter-Antonyan, A. Terliuk, S. Tilav, L. Tomankova, C. Tönnis, S. Toscano, D. Tosi, M. Tselengidou, C. F. Tung, A. Turcati, R. Turcotte, C. F. Turley, B. Ty, E. Unger, M. A. Unland Elorrieta, M. Usner, J. Vandenbroucke, W. Van Driessche, D. van Eijk, N. van Eijndhoven, S. Vanheule, J. van Santen, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, N. Wandkowsky, T. B. Watson, C. Weaver, M. J. Weiss, J. Weldert, C. Wendt, J. Werthebach, S. Westerhoff, B. J. Whelan, N. Whitehorn, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, J. Wood, T. R. Wood, K. Woschnagg, G. Wrede, S. Wren, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, T. Yuan, and Collaboration, IceCube

Subjects
Physics, Particle physics, Physics and Astronomy (miscellaneous), Field (physics), 010308 nuclear & particles physics, Oscillation, Sensitive analysis, Type (model theory), 7. Clean energy, 01 natural sciences, Measure (mathematics), Subatomär fysik, Upgrade, 0103 physical sciences, Subatomic Physics, Physique des particules élémentaires, Development (differential geometry), Neutrino, 010306 general physics, Engineering (miscellaneous)
Abstract

The Neutrino Mass Ordering (NMO) remains one of the outstanding questions in the field of neutrino physics. One strategy to measure the NMO is to observe matter effects in the oscillation pattern of atmospheric neutrinos above ∼1GeV, as proposed for several next-generation neutrino experiments. Moreover, the existing IceCube DeepCore detector can already explore this type of measurement. We present the development and application of two independent analyses to search for the signature of the NMO with three years of DeepCore data. These analyses include a full treatment of systematic uncertainties and a statistically-rigorous method to determine the significance for the NMO from a fit to the data. Both analyses show that the dataset is fully compatible with both mass orderings. For the more sensitive analysis, we observe a preference for normal ordering with a p-value of pIO= 15.3 % and CL s= 53.3 % for the inverted ordering hypothesis, while the experimental results from both analyses are consistent within their uncertainties. Since the result is independent of the value of δCP and obtained from energies Eν≳5GeV, it is complementary to recent results from long-baseline experiments. These analyses set the groundwork for the future of this measurement with more capable detectors, such as the IceCube Upgrade and the proposed PINGU detector., SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2020

15. Neutrinos below 100 TeV from the southern sky employing refined veto techniques to IceCube data

Author

A. O'Murchadha, D. J. Koskinen, Timothyblake Watson, Timo Karg, A. Kyriacou, E. Bourbeau, R. Maunu, C. Pérez de los Heros, T. Menne, Matthias Vraeghe, Maria Tselengidou, E. O’Sullivan, B. Relethford, J. Auffenberg, Raffaela Busse, D. Soldin, K. Rawlins, Claudio Kopper, J. Becker Tjus, Konstancja Satalecka, Subir Sarkar, Z. Griffith, Theo Glauch, R. Hellauer, K. Mallot, B. J. P. Jones, U. Katz, Minjin Jeong, James W. Wood, James Madsen, Thomas Meures, K. Hoshina, M. E. Huber, P. B. Price, Benjamin Hokanson-Fasig, N. L. Strotjohann, Segev BenZvi, Felix Henningsen, Glenn Spiczak, G. Momenté, M. Rameez, Lu Lu, Marcos Santander, R. Ström, Won Nam Kang, A. R. Fazely, H. Bagherpour, E. Pinat, P. Backes, X. Bai, D. van Eijk, Simona Toscano, D. F. Cowen, U. Naumann, K. D. de Vries, Spencer Klein, Andres Medina, Olga Botner, S. Tilav, E. Unger, L. Gerhardt, G. Neer, T. Kintscher, Francesco Lucarelli, Frederik Hermann Lauber, S. Hickford, A. Olivas, J. J. Beatty, Daniel Bindig, J. P. Yanez, N. Kulacz, G. H. Collin, Azadeh Keivani, T. Glüsenkamp, T. O. B. Schmidt, V. Baum, Teresa Montaruli, K. Jero, Tianlu Yuan, Sebastian Böser, C. Chen, Kara Hoffman, Kendall Mahn, K. Wiebe, J. Stettner, Hermann Kolanoski, A. Terliuk, S. Westerhoff, T. R. Wood, Justin Lanfranchi, R. Turcotte, K. Helbing, Yiqian Xu, Karl J. Clark, Matt Dunkman, Hrvoje Dujmovic, Sander Vanheule, Javier Gonzalez, L. Rauch, Anastasia Maria Barbano, Kurt Woschnagg, T. Kittler, G. W. Sullivan, Giorgio Maggi, James E. Braun, Alexander Sandrock, Thomas Ehrhardt, E. Cheung, Thomas Stuttard, H.-P. Bretz, Qinrui Liu, Martina Karl, M. Song, T. L. Carver, Mike Richman, Jochen M. Schneider, Paul Evenson, Hershal Pandya, C. De Clercq, Mirco Hunnefeld, Wolfgang Rhode, Dirk Ryckbosch, Nahee Park, K. Hultqvist, Stephan Meighen-Berger, Chunfai Tung, S. Yoshida, Elisa Bernardini, David A. Williams, Robert Stein, Lenka Tomankova, D. Hebecker, Karim Ghorbani, Spencer Axani, Simone Garrappa, Darren Grant, L. Wills, Markus Ackermann, S. W. Barwick, M. Stamatikos, D. Rysewyk, M. Silva, Kayla Leonard, M. J. Larson, M. A. Unland Elorrieta, Dmitry Chirkin, Sarah Mancina, Sarah Nowicki, Alexander Kappes, N. Kurahashi, Jenni Adams, I. Taboada, P. Peiffer, Joshua Hignight, Todor Stanev, C. Wendt, Paul Coppin, Michael O. Wolf, P. Nakarmi, Carlos Arguelles, J. P. A. M. de André, N. van Eijndhoven, C. Haack, Delia Tosi, Anna Franckowiak, Tobias Hoinka, Andrea Turcati, Jessie Micallef, A. Goldschmidt, Jung-Hyun Kim, Ibrahim Safa, Francis Halzen, P. Schlunder, G. de Wasseige, M. Wallraff, F. Huang, J. van Santen, A. Stößl, M. Börner, Steve Sclafani, Damian Pieloth, Ali Kheirandish, W. Van Driessche, J. Kiryluk, Alex Pizzuto, Daria Pankova, R. Hoffmann, E. Friedman, George Japaridze, Roger Moore, Gary Binder, Christian Spiering, D. R. Nygren, Reina H. Maruyama, I. Ansseau, K. Becker, Jan Soedingrekso, C. Walck, Marek Kowalski, Steven Robertson, Elisa Lohfink, K. Andeen, Jannes Brostean-Kaiser, Summer Blot, Thomas K. Gaisser, G. B. Yodh, J. Bourbeau, E. Jacobi, R. G. Stokstad, R. Nahnhauer, Gisela Anton, A. Stasik, Justin Vandenbroucke, Juliana Stachurska, H. Dembinski, Emily Dvorak, L. Köpke, Alexander Fritz, D. Z. Besson, Chad Finley, G. Krückl, L. Schumacher, Carsten Rott, Tim Ruhe, Colin Turley, C. Alispach, Seongjin In, Gerald Przybylski, Elisa Resconi, T. Anderson, M. G. Aartsen, Janet Conrad, Federica Bradascio, Alexander Burgman, Pablo Correa, H. Niederhausen, K. Mase, Yuya Makino, R. Cross, Xianwu Xu, Christoph Tönnis, J. Sandroos, Mehmet Gunduz, Johannes Werthebach, M. S. Sutherland, A. Ishihara, R. C. Bay, M. J. Weiss, Kirill Filimonov, Austin Schneider, J. C. Gallagher, Juan Carlos Diaz-Velez, M. Usner, S. Kopper, M. Leuermann, Gerrit Wrede, Kael Hanson, René Reimann, William Luszczak, Allan Hallgren, M. Kauer, Martin Rongen, Pranav Dave, Samridha Kunwar, D. Altmann, K. Meagher, David Kappesser, L. Wille, S. E. Sanchez Herrera, Maximilian Meier, T. Palczewski, Paolo Desiati, M. Günder, D. Heereman, T. Stezelberger, A. Steuer, B. Eberhardt, Raamis Hussain, J. Lünemann, Amirreza Raissi, Chris Weaver, Stephanie Bron, C. J. Lozano Mariscal, G. Merino, N. Wandkowsky, Surujhdeo Seunarine, R. Snihur, Juanan Aguilar, B. J. Whelan, Immacolata Carmen Rea, K. Krings, Jan Weldert, L. Halve, Philipp Eller, M. Plum, Ramesh Koirala, E. Blaufuss, J. Felde, Merlin Schaufel, L. Classen, A. Obertacke Pollmann, A. Wallace, J. L. Kelley, Da Xu, Markus Ahlers, James DeLaunay, Marjon Moulai, S. De Ridder, Christopher Wiebusch, Kunal Deoskar, M. Labare, A. Karle, Erik Ganster, Ioana Codrina Maris, Christian Bohm, Samvel Ter-Antonyan, Christoph Raab, Nadège Iovine, D. Berley, G. C. Hill, Bunheng Ty, Maryon Ahrens, Giovanni Renzi, D. Seckel, Frederik Tenholt, S. Fahey, R. Nagai, M. Medici, S. Miarecki, Tyce DeYoung, Nathan Whitehorn, Jeffrey Lazar, Physics, Faculty of Sciences and Bioengineering Sciences, Vriendenkring VUB, and Elementary Particle Physics

Subjects
background [atmosphere], Physics::Instrumentation and Detectors, media_common.quotation_subject, Astrophysics::High Energy Astrophysical Phenomena, pole, FOS: Physical sciences, 01 natural sciences, High Energy Physics - Experiment, IceCube Neutrino Observatory, IceCube, charged current, High Energy Physics - Experiment (hep-ex), Neutrinos, Point sources, Veto techniques, SEARCH, TRACK RECONSTRUCTION, 0103 physical sciences, supernova, Muon neutrino, atmosphere [muon], 010303 astronomy & astrophysics, Astrophysics::Galaxy Astrophysics, media_common, High Energy Astrophysical Phenomena (astro-ph.HE), Physics, neutrino muon, Muon, 010308 nuclear & particles physics, ICE, Galactic Center, High Energy Physics::Phenomenology, Astronomy, Astronomy and Astrophysics, flux [neutrino], Galactic plane, observatory, Supernova, Physics and Astronomy, Sky, energy [neutrino], gamma ray, ddc:540, spectral, High Energy Physics::Experiment, galaxy, Neutrino, Astrophysics - High Energy Astrophysical Phenomena
Abstract

Many Galactic sources of gamma rays, such as supernova remnants, are expected to produce neutrinos with a typical energy cutoff well below 100 TeV. For the IceCube Neutrino Observatory located at the South Pole, the southern sky, containing the inner part of the Galactic plane and the Galactic Center, is a particularly challenging region at these energies, because of the large background of atmospheric muons. In this paper, we present recent advancements in data selection strategies for track-like muon neutrino events with energies below 100 TeV from the southern sky. The strategies utilize the outer detector regions as veto and features of the signal pattern to reduce the background of atmospheric muons to a level which, for the first time, allows IceCube searching for point-like sources of neutrinos in the southern sky at energies between 100 GeV and several TeV in the muon neutrino charged current channel. No significant clustering of neutrinos above background expectation was observed in four years of data recorded with the completed IceCube detector. Upper limits on the neutrino flux for a number of spectral hypotheses are reported for a list of astrophysical objects in the southern hemisphere., 19 pages, 17 figures, 2 tables

Published
2020

16. The IceCube realtime alert system

Author

B. J. P. Jones, Chris Wendt, S. Hickford, D. Tosi, M. Day, R. Konietz, M. Vehring, S. Coenders, Joshua Hignight, Francis Halzen, Karim Ghorbani, S. Seunarine, G. Merino, Spencer Axani, I. Ansseau, N. Wandkowsky, S. Schoenen, J. Kiryluk, M. Wolf, F. Bos, A. Terliuk, Sally Robertson, G. Krückl, Carlos Arguelles, M. Song, T. L. Carver, Mike Richman, H. Dembinski, Sebastian Böser, D. Heereman, P. Schlunder, R. Nahnhauer, M. Lesiak-Bzdak, Gisela Anton, V. di Lorenzo, Allan Hallgren, J. Tatar, M. J. Larson, Jae Yool Kim, M. Kauer, L. Classen, Kurt Woschnagg, T. Menne, Paul Evenson, L. Brayeur, C. Finley, Juanan Aguilar, Jenni Adams, Hrvoje Dujmovic, Janet Conrad, B. Relethford, Ignacio Taboada, A. Obertacke Pollmann, K. Rawlins, M. G. Aartsen, Michael Sutherland, K. Mase, T. Kittler, S. Flis, P. Peiffer, R. Cross, K. D. de Vries, George Japaridze, S. De Ridder, Dirk Lennarz, Konstancja Satalecka, Theo Glauch, M. Rongen, Gabriel Collin, Dmitry Chirkin, A. Franckowiak, D. Z. Besson, Marjon Moulai, James Madsen, Lu Lu, R. Maunu, E. Friedman, Alexander Kappes, R. G. Stokstad, Markus Ahlers, J. Kunnen, Jay Gallagher, T. Ehrhardt, N. van Eijndhoven, M. N. Tobin, A. Meli, C.-C. Fösig, M. van Rossem, M. Vraeghe, C. Haack, K. Meagher, Elisa Resconi, A. Steuer, Teresa Montaruli, M. J. Weiss, N. Kurahashi, B. J. Whelan, Todor Stanev, R. Hellauer, D. Bose, Kendall Mahn, N. L. Strotjohann, J. P. Dumm, M. Relich, A. Olivas, K. Helbing, T. Palczewski, H. Pandya, M. Bissok, K. Jero, A. Wallace, R. Reimann, E. Vogel, Maryon Ahrens, U. Katz, J. C. Díaz-Vélez, S. Kopper, E. Woolsey, G. Binder, Joshua Pepper, H. Niederhausen, Dawn Williams, F. Huang, M. Leuermann, G. de Wasseige, A. Turcati, U. Naumann, E. Hansen, M. E. Huber, B. Eberhardt, M. S. Kim, Samvel Ter-Antonyan, Aya Ishihara, D. Bindig, E. Jacobi, Elisa Bernardini, Segev BenZvi, G. Maggi, T. Schmidt, L. Wille, Y. Xu, J. Lünemann, M. Kowalski, S. E. Sanchez Herrera, Azadeh Keivani, Frederik Tenholt, M. Rameez, M. Medici, L. Gerhardt, D. F. Cowen, Albrecht Karle, S. Euler, T. Fuchs, T. Karg, Ch. Weaver, Alexander Burgman, W. Kang, Z. Griffith, S. Miarecki, J. van Santen, Kael Hanson, Thomas Meures, K. Krings, K. Clark, D. V. Pankova, F. McNally, G. W. Sullivan, M. Casier, B. Riedel, D. R. Nygren, S. Bron, Steven W. Barwick, M. Tselengidou, Thomas K. Gaisser, G. B. Yodh, Spencer Klein, A. Stasik, Stijn Vanheule, Philipp Eller, Maximilian Meier, T. Ruhe, S. Wickmann, J. Auffenberg, D. Hebecker, Paolo Desiati, A. Sandrock, T. Glüsenkamp, Gerald Przybylski, Minjin Jeong, G. Neer, T. Kintscher, Hermann Kolanoski, M. Labare, M. Quinnan, M. Dunkman, J. Felde, H. Taavola, Stijn Blot, Christian Spiering, S. Yoshida, Xinhua Bai, T. Hansmann, R. Hoffmann, Javier Gonzalez, M. Mandelartz, E. Blaufuss, Kara Hoffman, E. Pinat, Olga Botner, K. Wiebe, P. B. Price, V. Baum, D. J. Koskinen, D. Ryckbosch, Simona Toscano, M. Voge, Markus Ackermann, Donglian Xu, J. Becker Tjus, Ö. Penek, D. Soldin, L. Rädel, J. Stettner, Justin Vandenbroucke, K. Hoshina, E. del Pino Rosendo, Subir Sarkar, Glenn Spiczak, S. Schöneberg, K. H. Becker, E. Unger, D. Berley, W. Giang, J. L. Lanfranchi, Wolfgang Rhode, J. L. Kelley, S. In, S. C. Nowicki, L. Gladstone, R. Koirala, Darren Grant, J. P. A. M. de André, C. Walck, Sarah Mancina, Frederik Hermann Lauber, M. Börner, Klas Hultqvist, M. Zoll, K. Andeen, S. Westerhoff, A. Christov, M. Wallraff, T. Stezelberger, E. Cheung, M. Usner, L. Sabbatini, B. Eichmann, H.-P. Bretz, S. Tilav, Christian Bohm, Aongus O'Murchadha, J. P. Yanez, Christoph Raab, G. C. Hill, L. Schumacher, C. Krüger, A. Goldschmidt, R. C. Bay, D. Seckel, S. Fahey, S. Kunwar, M. Archinger, A. R. Fazely, Tyce DeYoung, P. A. Toale, M. Kroll, C. Kopper, J. Braun, T. R. Wood, J. J. Beatty, A. Bernhard, D. Rysewyk, A. Stößl, Reina H. Maruyama, Christopher Wiebusch, J. Feintzeig, Carsten Rott, Xianwu Xu, J. Sandroos, D. Altmann, C. Pérez de los Heros, R. Ström, T. Kuwabara, L. Wills, Damian Pieloth, Ali Kheirandish, L. Köpke, G. Kohnen, T. Anderson, C. De Clercq, G. Tešić, Kirill Filimonov, Physics, Elementary Particle Physics, Faculty of Sciences and Bioengineering Sciences, and Vriendenkring VUB

Subjects
HIGH-ENERGY NEUTRINOS, TELESCOPE, Astrophysics::High Energy Astrophysical Phenomena, Multi-messenger astronomy, Neutrino astronomy, Neutrino detectors, Transient sources, Astronomy and Astrophysics, pole, FOS: Physical sciences, 01 natural sciences, IceCube, law.invention, IceCube Neutrino Observatory, Telescope, SEARCHES, CORE-COLLAPSE SUPERNOVAE, law, Observatory, 0103 physical sciences, site, 010306 general physics, Instrumentation and Methods for Astrophysics (astro-ph.IM), 010303 astronomy & astrophysics, High Energy Astrophysical Phenomena (astro-ph.HE), Physics, background, Event (computing), Astrophysics::Instrumentation and Methods for Astrophysics, Astronomy, PERFORMANCE, sensitivity, observatory, Identification (information), electromagnetic, Physics and Astronomy, Neutrino detector, ddc:540, High Energy Physics::Experiment, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, Astrophysics - Instrumentation and Methods for Astrophysics, FOLLOW-UP
Abstract

Following the detection of high-energy astrophysical neutrinos in 2013, their origin is still unknown. Aiming for the identification of an electromagnetic counterpart of a rapidly fading source, we have implemented a realtime analysis framework for the IceCube neutrino observatory. Several analyses selecting neutrinos of astrophysical origin are now operating in realtime at the detector site in Antarctica and are producing alerts to the community to enable rapid follow-up observations. The goal of these observations is to locate the astrophysical objects responsible for these neutrino signals. This paper highlights the infrastructure in place both at the South Pole detector site and at IceCube facilities in the north that have enabled this fast follow-up program to be developed. Additionally, this paper presents the first realtime analyses to be activated within this framework, highlights their sensitivities to astrophysical neutrinos and background event rates, and presents an outlook for future discoveries., Comment: 33 pages, 9 figures, Published in Astroparticle Physics

Published
2017

17. Time-integrated Neutrino Source Searches with 10 years of IceCube Data

Author

Federica Bradascio, Alexander Burgman, Merlin Schaufel, Daria Pankova, E. Friedman, Claudio Kopper, Subir Sarkar, Chad Finley, J. J. Beatty, Tianlu Yuan, M. Kauer, D. Kang, Christoph Tönnis, Frank G. Schröder, Alexander Fritz, D. Z. Besson, K. Mase, Yuya Makino, R. Morse, Suyong Choi, I. Taboada, R. Maunu, David Kappesser, Michael O. Wolf, Minjin Jeong, Thomas Meures, N. L. Strotjohann, Felix Henningsen, A. R. Fazely, E. Pinat, Simona Toscano, P. Heix, K. Jero, Sander Vanheule, N. Kurahashi, Karl J. Clark, S. De Ridder, Z. Griffith, Jenni Adams, J. Lünemann, C. Pérez de los Heros, A. Obertacke Pollmann, Aswathi Balagopal, Saskia Philippen, D. Rysewyk, M. Song, T. L. Carver, Mike Richman, J. L. Kelley, Markus Ahlers, K. Meagher, F. McNally, M. J. Weiss, M. Labare, T. Palczewski, C. Wendt, E. O’Sullivan, S. Hickford, Jan Soedingrekso, M. Stamatikos, S. Kopper, René Reimann, A. O'Murchadha, Lenka Tomankova, Chunfai Tung, P. Peiffer, M. J. Larson, Pranav Dave, Timothyblake Watson, Erik Ganster, T. Menne, G. de Wasseige, B. Eberhardt, A. Stößl, L. Rauch, Benjamin Hokanson-Fasig, Yang Lyu, Samvel Ter-Antonyan, M. Silva, R. G. Stokstad, B. Relethford, S. Yoshida, Won Nam Kang, Amirreza Raissi, Chris Weaver, Stephanie Bron, Max Renschler, D. J. Koskinen, Wing Yan Ma, Tim Ruhe, B. J. P. Jones, R. Hoffmann, B. J. Whelan, X. Bai, G. Neer, E. Bourbeau, C. J. Lozano Mariscal, G. Merino, Reina H. Maruyama, James DeLaunay, C. Alispach, G. Krückl, Konstancja Satalecka, N. Wandkowsky, H. Dujmovic, Janet Conrad, K. Wiebe, Marjon Moulai, Summer Blot, Andres Medina, Theo Glauch, Jan Weldert, Thomas Ehrhardt, Spencer Griswold, Steven Robertson, Joshua Hignight, L. Halve, Philipp Eller, Shefali Shefali, D. Mockler, M. Günder, Alejandro Diaz, R. Cross, Timo Sturwald, H. Niederhausen, Kael Hanson, Surujhdeo Seunarine, R. Snihur, A. Weindl, Maria Tselengidou, D. Soldin, Johannes Werthebach, Carsten Rott, Juanan Aguilar, T. Stezelberger, R. Joppe, D. van Eijk, Joshua A. Wood, J. Felde, C. Walck, Jeffrey Lazar, R. Hellauer, J. Buscher, P. Schlunder, Maryon Ahrens, Alan Coleman, William Luszczak, Alexander Sandrock, Frederik Tenholt, R. Nagai, A. Goldschmidt, L. Schumacher, M. Zöcklein, Xianwu Xu, M. Medici, J. Sandroos, Timo Karg, T. Stanev, Maximilian Meier, Thomas K. Gaisser, G. B. Yodh, P. Steinmüller, F. Huang, G. H. Collin, Matthias Vraeghe, J. Stettner, J. Kim, Delia Tosi, U. Katz, Mehmet Gunduz, Agnieszka Leszczyńska, M. E. Huber, Marcos Santander, Paolo Desiati, S. E. Sanchez Herrera, R. C. Bay, K. D. de Vries, Sebastian Baur, Sebastian Böser, P. Backes, Gisela Anton, Elisa Bernardini, G. W. Sullivan, H. S. Matis, D. B. Fox, L. Gerhardt, A. Olivas, Austin Schneider, James E. Braun, N. van Eijndhoven, K. Helbing, C. Haack, Juan Carlos Diaz-Velez, H. Bagherpour, Benjamin Bastian, Anastasia Maria Barbano, T. Kittler, Daniel Bindig, Hermann Kolanoski, K. Becker, Emily Dvorak, N. Kulacz, Olga Botner, Kayla Leonard, D. R. Nygren, Javier Gonzalez, Roxanne Turcotte, Marek Kowalski, D. Hebecker, F. Jonske, Alexander Trettin, Giorgio Maggi, Mirco Hunnefeld, Marie Oehler, V. Baum, Sarah Mancina, Anna Franckowiak, Tobias Hoinka, Francis Halzen, J. Auffenberg, M. Börner, Steve Sclafani, J. Kiryluk, C. De Clercq, S. Tilav, I. Ansseau, Paul Coppin, Andrea Turcati, J. C. Gallagher, M. Leuermann, K. Andeen, Elisa Lohfink, J. P. Yanez, Gerrit Wrede, K. Hoshina, Thomas Huber, David A. Williams, Allan Hallgren, Juliana Stachurska, J. van Santen, H. Dembinski, Alex Pizzuto, Markus Ackermann, Glenn Spiczak, G. Momenté, M. G. Aartsen, Pablo Correa, S. W. Barwick, M. Rameez, D. F. Cowen, Gary Binder, Gerald Przybylski, U. Naumann, R. Halliday, George Japaridze, Roger Moore, E. Unger, A. Kyriacou, J. Bourbeau, K. Krings, Seongjin In, Elisa Resconi, Yiqian Xu, Matt Dunkman, Alessio Porcelli, M. Plum, J. Becker Tjus, E. Cheung, Ramesh Koirala, Thomas Stuttard, Dirk Ryckbosch, Stephan Meighen-Berger, K. Tollefson, E. Blaufuss, Albrecht Karle, Qinrui Liu, T. Glüsenkamp, L. Classen, Martina Karl, Jochen M. Schneider, M. A. Unland Elorrieta, D. Heereman, M. Wallraff, A. Steuer, Raamis Hussain, Colin Turley, T. Anderson, Immacolata Carmen Rea, Andreas Haungs, A. Ishihara, K. Mallot, H. Schieler, Kirill Filimonov, Segev BenZvi, T. Kintscher, M. Usner, Frederik Hermann Lauber, Spencer Klein, A. Terliuk, Justin Lanfranchi, Kara Hoffman, Julia Böttcher, Christian Spiering, Hershal Pandya, Wolfgang Rhode, Robert Stein, Justin Vandenbroucke, L. Wills, P. Muth, Ioana Codrina Maris, S. C. Nowicki, Christian Bohm, Ibrahim Safa, Damian Pieloth, Ali Kheirandish, W. Van Driessche, Nahee Park, K. Hultqvist, Darren Grant, Jannes Brostean-Kaiser, Christoph Raab, Nadège Iovine, M. U. Nisa, L. Köpke, D. Berley, G. C. Hill, Bunheng Ty, Ralph Engel, Giovanni Renzi, K. Rawlins, D. Seckel, S. Fahey, Tyce DeYoung, Nathan Whitehorn, Martin Rongen, R. S. Busse, Christopher Wiebusch, Kunal Deoskar, James Madsen, Lu Lu, L. Wille, Teresa Montaruli, Kendall Mahn, P. B. Price, Francesco Lucarelli, T. O. B. Schmidt, C. Chen, Karim Ghorbani, Spencer Axani, T. R. Wood, Carlos Arguelles, Jessie Micallef, P. Mallik, Kurt Woschnagg, Paul Evenson, Simone Garrappa, Dmitry Chirkin, Alexander Kappes, A. Wallace, Da Xu, Physics, Faculty of Sciences and Bioengineering Sciences, Elementary Particle Physics, and Vriendenkring VUB

Subjects
background [atmosphere], Astrophysics::High Energy Astrophysical Phenomena, media_common.quotation_subject, General Physics and Astronomy, FOS: Physical sciences, Astrophysics::Cosmology and Extragalactic Astrophysics, 01 natural sciences, IceCube, particle source [neutrino], TRACK RECONSTRUCTION, 0103 physical sciences, ddc:530, atmosphere [muon], 010306 general physics, Astrophysics::Galaxy Astrophysics, media_common, astro-ph.HE, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), Muon, Astrophysics::Instrumentation and Methods for Astrophysics, Northern Hemisphere, Astronomy, Galaxy, messenger, Physics and Astronomy, Sky, correlation, time dependence, upgrade, galaxy, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, statistical
Abstract

Physical review letters 124(5), 051103 (1-9) (2020). doi:10.1103/PhysRevLett.124.051103, This paper presents the results from point-like neutrino source searches using ten years of IceCube data collected between April 6, 2008 and July 10, 2018. We evaluate the significance of an astrophysical signal from a point-like source looking for an excess of clustered neutrino events with energies typically above $\sim1\,$TeV among the background of atmospheric muons and neutrinos. We perform a full-sky scan, a search within a selected source catalog, a catalog population study, and three stacked Galactic catalog searches. The most significant point in the Northern hemisphere from scanning the sky is coincident with the Seyfert II galaxy NGC 1068, which was included in the source catalog search. The excess at the coordinates of NGC 1068 is inconsistent with background expectations at the level of $2.9\,\sigma$ after accounting for statistical trials. The combination of this result along with excesses observed at the coordinates of three other sources, including TXS 0506+056, suggests that, collectively, correlations with sources in the Northern catalog are inconsistent with background at 3.3$\,\sigma$ significance. These results, all based on searches for a cumulative neutrino signal integrated over the ten years of available data, motivate further study of these and similar sources, including time-dependent analyses, multimessenger correlations, and the possibility of stronger evidence with coming upgrades to the detector., Published by APS, College Park, Md.

Published
2019
Full Text
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18. Early recurrence in a pooled international cohort of melanoma patients treated with adjuvant nivolumab in a real-world setting

Author

L. Mortier, R. Gutzmer, V. Atkinson, S. Dalle, P. Saiag, B. Neyns, A. Rorive, P. Parente, M. Weichenthal, J.-J. Grob, C. Lebbé, P. Mohr, T. Eigentler, L. McDonald, L. Willemot, F. Brellier, O. Bakharevski, S. Houssou, M. Jadhao, and D. Schadendorf

Subjects
Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Published
2024
Full Text
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19. Roll Stabilization Control of Sailboats

Author

Vahid Hassani, Kristian L. Wille, and Florian Sprenger

Subjects
0209 industrial biotechnology, Engineering, business.industry, 020208 electrical & electronic engineering, Stabilization control, Crew, 02 engineering and technology, Linear-quadratic regulator, Relative wind, 020901 industrial engineering & automation, Control and Systems Engineering, Robustness (computer science), Control theory, Lookup table, 0202 electrical engineering, electronic engineering, information engineering, business
Abstract

This paper reports a way of dynamically controlling the sail of a sailboat to reduce the heel angle and roll motion caused by the wind. This is mainly to increase robustness and safety for autonomous sailboats but could also be used to increase comfort for crew. The solution consists of a linear quadratic regulator (LQR) controlling the moment created by the sail. A lookup table will then choose the optimal angle of the sail, optimized for maximum forward acceleration, given the relative wind direction and desired moment. Simulation results are presented to show the effectiveness of the approach.

Published
2016

20. Modeling and Course Control of Sailboats

Author

Florian Sprenger, Vahid Hassani, and Kristian L. Wille

Subjects
0209 industrial biotechnology, Engineering, Heading (navigation), Keel, 010505 oceanography, business.industry, Work (physics), Control (management), Control engineering, 02 engineering and technology, 01 natural sciences, Course (navigation), Term (time), 020901 industrial engineering & automation, Control and Systems Engineering, Drag, Control theory, business, 0105 earth and related environmental sciences
Abstract

This paper proposes a method of transforming a heading controller into a course controller in sailboats by adding a small correction term. Sailboats usually have large drift angles because of considerable side forces, mainly caused by the sail. Even small deviations from the correct course angle can cause large errors, and thus course controllers in sailboats plays an essential role. The solution is based on the dynamics of the system, and the model presented builds upon previous work and adds detail in areas such as how to model wind, current and drag. The solution has roots in the fact that the purpose of the keel is to create a side force that counterbalances the unwanted drift forces. Simulation results show the effectiveness of the proposed approach.

Published
2016

21. Astrophysical neutrinos and cosmic rays observed by IceCube

Author

D. Hebecker, Andrea Turcati, M. Kroll, K. Krings, J. van Santen, K. D. de Vries, G. Merino, N. Wandkowsky, Segev BenZvi, R. Maunu, Spencer Klein, M. Mandelartz, M. Usner, Ramesh Koirala, J. Becker Tjus, Dennis Soldin, G. H. Collin, H. Taavola, Gary Binder, E. Blaufuss, T. Kuwabara, Surujhdeo Seunarine, L. Classen, Kara Hoffman, Juanan Aguilar, S. De Ridder, M. Labare, M. van Rossem, K. Rawlins, Maryon Ahrens, Frederik Tenholt, M. Medici, B. J. Whelan, M. Relich, A. Ishihara, J. Veenkamp, S. Coenders, C. Pérez de los Heros, H.-P. Bretz, Killian Holzapfel, Hershal Pandya, Frank McNally, Martin Rongen, Francis Halzen, Wolfgang Rhode, A. Christov, A. Meli, L. Wille, James Madsen, S. E. Sanchez Herrera, A. Goldschmidt, D. Z. Besson, Lu Lu, Z. Griffith, T. Kintscher, S. Euler, Hans Niederhausen, A. Bernhard, K. Clark, I. Ansseau, H. Dembinski, J. C. Gallagher, Thomas Meures, L. Wills, B. J. P. Jones, Ch. Weaver, M. N. Tobin, A. Stasik, Frederik Hermann Lauber, R. Konietz, M. Leuermann, J. Feintzeig, N. L. Strotjohann, J. Kunnen, Jenni Adams, N. Kurahashi, Todor Stanev, C. Wendt, Chad Finley, A. Wallace, G. de Wasseige, K. Meagher, F. Bos, J. Lünemann, Damian Pieloth, Ali Kheirandish, Tim Ruhe, K.-H. Becker, Janet Conrad, T. Stezelberger, R. Hoffmann, M. Day, B. Riedel, Yiqian Xu, Matt Dunkman, R. G. Stokstad, A. R. Fazely, R. Cross, Joshua Hignight, Da Xu, Allan Hallgren, C. Walck, A. Terliuk, S. Westerhoff, Justin Lanfranchi, Stephanie Bron, Philipp Eller, Sarah Mancina, Albrecht Karle, M. S. Sutherland, Kendall Mahn, C.-C. Fösig, Sandro Kopper, T. Fuchs, E. Pinat, Kael Hanson, K. Wiebe, Thomas K. Gaisser, G. B. Yodh, E. Cheung, Christian Spiering, D. R. Nygren, P. Schlunder, L. Köpke, Simona Toscano, M. Kauer, M. Börner, J. Kiryluk, K. Jero, G. Krückl, Dirk Ryckbosch, Marek Kowalski, K. Andeen, Matthias Wolf, M. Vehring, D. Altmann, Alexander Burgman, T. Anderson, D. Bose, P. B. Price, Justin Vandenbroucke, Javier Gonzalez, J. P. Dumm, Azadeh Keivani, Thomas Ehrhardt, T. Palczewski, J. Felde, S. Schöneberg, Karim Ghorbani, Spencer Axani, M. Song, M. Lesiak-Bzdak, L. Brayeur, L. Sabbatini, T. L. Carver, Mike Richman, Giorgio Maggi, Maximilian Meier, T. O. B. Schmidt, D. Heereman, G. Tešić, Daria Pankova, E. Vogel, M. S. Kim, Dirk Lennarz, S. Wickmann, J. Auffenberg, Paolo Desiati, T. R. Wood, R. Nahnhauer, Gisela Anton, E. Friedman, R. Hellauer, I. Taboada, A. Steuer, E. del Pino Rosendo, A. Obertacke Pollmann, S. Kunwar, Subir Sarkar, Minjin Jeong, Carlos Arguelles, S. Schoenen, W. Giang, S. Flis, S. Tilav, C. De Clercq, K. Mase, B. Eberhardt, Kurt Woschnagg, Paul Evenson, J. P. Yanez, J. L. Kelley, Markus Ahlers, Kirill Filimonov, Sally Robertson, Matthias Vraeghe, Sebastian Böser, G. W. Sullivan, David A. Williams, M. J. Weiss, Carsten Rott, James E. Braun, J. Kim, Christopher Wiebusch, George Japaridze, Dmitry Chirkin, S. Hickford, K. Helbing, Björn Eichmann, T. Kittler, Markus Ackermann, S. W. Barwick, M. Bissok, Alexander Kappes, K. Hultqvist, S. Yoshida, T. Hansmann, E. Woolsey, Darren Grant, T. Montaruli, N. van Eijndhoven, Xianwu Xu, Joshua Pepper, J. Sandroos, René Reimann, E. Jacobi, Samvel Ter-Antonyan, C. Haack, C. Bohm, Delia Tosi, Daniel Bindig, Christoph Raab, Sarah Nowicki, Seongjin In, Elisa Resconi, J. Tatar, Elisa Bernardini, D. Berley, G. C. Hill, R. Ström, J. P. A. M. de André, Won Nam Kang, M. Jurkovic, L. Gladstone, C. Krüger, D. Seckel, S. Fahey, M. G. Aartsen, S. Miarecki, X. Bai, G. Neer, P. Peiffer, T. Menne, Tyce DeYoung, L. Schumacher, P. A. Toale, B. Relethford, Konstancja Satalecka, Theo Glauch, M. Casier, U. Katz, Alexander Sandrock, R. C. Bay, Hermann Kolanoski, J. Stettner, Juan Carlos Diaz-Velez, M. Archinger, A. Olivas, K. Hoshina, F. Huang, Glenn Spiczak, M. Rameez, D. F. Cowen, C. Kopper, U. Naumann, E. Unger, J. J. Beatty, A. O'Murchadha, D. J. Koskinen, D. Rysewyk, A. Stößl, Reina H. Maruyama, Maria Tselengidou, Ö. Penek, Summer Blot, L. Rädel, Timo Karg, E. Hansen, M. E. Huber, L. Gerhardt, M. J. Larson, M. Quinnan, A. Franckowiak, Marjon Moulai, Olga Botner, V. Baum, Gerald Przybylski, M. Zoll, Hrvoje Dujmovic, Sander Vanheule, G. Kohnen, V. di Lorenzo, T. Glüsenkamp, M. Wallraff, M. Voge, Physics, Elementary Particle Physics, Vriendenkring VUB, and Faculty of Sciences and Bioengineering Sciences

Subjects
Atmospheric Science, Astrophysics::High Energy Astrophysical Phenomena, Aerospace Engineering, Cosmic ray, Astrophysics, Physics and Astronomy(all), 7. Clean energy, 01 natural sciences, IceCube Neutrino Observatory, IceCube, cosmic rays, Observatory, 0103 physical sciences, Neutrinos, 010303 astronomy & astrophysics, Cosmic rays, Physics, Muon, 010308 nuclear & particles physics, Gamma ray, Astrophysics::Instrumentation and Methods for Astrophysics, neutrinos, Astronomy, Astronomy and Astrophysics, Geophysics, Space and Planetary Science, Neutrino detector, 13. Climate action, Physique des particules élémentaires, General Earth and Planetary Sciences, Neutrino, Neutrino astronomy
Abstract

The core mission of the IceCube neutrino observatory is to study the origin and propagation of cosmic rays. IceCube, with its surface component IceTop, observes multiple signatures to accomplish this mission. Most important are the astrophysical neutrinos that are produced in interactions of cosmic rays, close to their sources and in interstellar space. IceCube is the first instrument that measures the properties of this astrophysical neutrino flux and constrains its origin. In addition, the spectrum, composition, and anisotropy of the local cosmic-ray flux are obtained from measurements of atmospheric muons and showers. Here we provide an overview of recent findings from the analysis of IceCube data, and their implications to our understanding of cosmic rays., 0, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2018

22. Constraints on Minute-Scale Transient Astrophysical Neutrino Sources

Author

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, I. Al Samarai, D. Altmann, K. Andeen, T. Anderson, I. Ansseau, G. Anton, C. Argüelles, J. Auffenberg, S. Axani, P. Backes, H. Bagherpour, X. Bai, A. Barbano, J. P. Barron, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, J. Becker Tjus, K.-H. Becker, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, F. Bos, S. Böser, O. Botner, E. Bourbeau, J. Bourbeau, F. Bradascio, J. Braun, M. Brenzke, H.-P. Bretz, S. Bron, J. Brostean-Kaiser, A. Burgman, R. S. Busse, T. Carver, E. Cheung, D. Chirkin, A. Christov, K. Clark, L. Classen, G. H. Collin, J. M. Conrad, P. Coppin, P. Correa, D. F. Cowen, R. Cross, P. Dave, M. Day, J. P. A. M. de André, C. De Clercq, J. J. DeLaunay, H. Dembinski, K. Deoskar, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, J. C. Díaz-Vélez, V. di Lorenzo, H. Dujmovic, J. P. Dumm, M. Dunkman, E. Dvorak, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, P. A. Evans, P. A. Evenson, S. Fahey, A. R. Fazely, J. Felde, K. Filimonov, C. Finley, A. Franckowiak, E. Friedman, A. Fritz, T. K. Gaisser, J. Gallagher, E. Ganster, L. Gerhardt, K. Ghorbani, W. Giang, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, C. Haack, A. Hallgren, L. Halve, F. Halzen, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, T. Hoinka, B. Hokanson-Fasig, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, M. Hünnefeld, R. Hussain, S. In, N. Iovine, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, P. Kalaczynski, W. Kang, A. Kappes, D. Kappesser, T. Karg, A. Karle, U. Katz, M. Kauer, A. Keivani, J. L. Kelley, A. Kheirandish, J. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, R. Koirala, H. Kolanoski, L. Köpke, C. Kopper, S. Kopper, J. P. Koschinsky, D. J. Koskinen, M. Kowalski, K. Krings, M. Kroll, G. Krückl, S. Kunwar, N. Kurahashi, A. Kyriacou, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, K. Leonard, M. Leuermann, Q. R. Liu, E. Lohfink, C. J. Lozano Mariscal, L. Lu, J. Lünemann, W. Luszczak, J. Madsen, G. Maggi, K. B. M. Mahn, Y. Makino, S. Mancina, I. C. Mariş, R. Maruyama, K. Mase, R. Maunu, K. Meagher, M. Medici, M. Meier, T. Menne, G. Merino, T. Meures, S. Miarecki, J. Micallef, G. Momenté, T. Montaruli, R. W. Moore, M. Moulai, R. Nagai, R. Nahnhauer, P. Nakarmi, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, J. P. Osborne, E. O’Sullivan, T. Palczewski, H. Pandya, D. V. Pankova, P. Peiffer, J. A. Pepper, C. Pérez de los Heros, D. Pieloth, E. Pinat, A. Pizzuto, M. Plum, P. B. Price, G. T. Przybylski, C. Raab, M. Rameez, L. Rauch, K. Rawlins, I. C. Rea, R. Reimann, B. Relethford, G. Renzi, E. Resconi, W. Rhode, M. Richman, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, I. Safa, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, M. Santander, S. Sarkar, K. Satalecka, M. Schaufel, P. Schlunder, T. Schmidt, A. Schneider, J. Schneider, S. Schöneberg, L. Schumacher, S. Sclafani, D. Seckel, S. Seunarine, J. Soedingrekso, D. Soldin, M. Song, G. M. Spiczak, C. Spiering, J. Stachurska, M. Stamatikos, T. Stanev, A. Stasik, R. Stein, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, N. L. Strotjohann, T. Stuttard, G. W. Sullivan, M. Sutherland, I. Taboada, F. Tenholt, S. Ter-Antonyan, A. Terliuk, S. Tilav, P. A. Toale, M. N. Tobin, C. Tönnis, S. Toscano, D. Tosi, M. Tselengidou, C. F. Tung, A. Turcati, C. F. Turley, B. Ty, E. Unger, M. A. Unland Elorrieta, M. Usner, J. Vandenbroucke, W. Van Driessche, D. van Eijk, N. van Eijndhoven, S. Vanheule, J. van Santen, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, F. D. Wandler, N. Wandkowsky, T. B. Watson, A. Waza, C. Weaver, M. J. Weiss, C. Wendt, J. Werthebach, S. Westerhoff, B. J. Whelan, N. Whitehorn, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, J. Wood, T. R. Wood, E. Woolsey, K. Woschnagg, G. Wrede, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, T. Yuan, Physics, Faculty of Sciences and Bioengineering Sciences, Vriendenkring VUB, and Elementary Particle Physics

Subjects
HIGH-ENERGY NEUTRINOS, Astrophysics::High Energy Astrophysical Phenomena, Population, General Physics and Astronomy, FOS: Physical sciences, Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, 01 natural sciences, 7. Clean energy, 0103 physical sciences, Muon neutrino, ddc:530, education, 010303 astronomy & astrophysics, Physics, GAMMA-RAY BURSTS, High Energy Astrophysical Phenomena (astro-ph.HE), education.field_of_study, Muon, 010308 nuclear & particles physics, Supernova, Neutron star, Physics and Astronomy, 13. Climate action, Physique des particules élémentaires, High Energy Physics::Experiment, Neutrino, Gamma-ray burst, Astrophysics - High Energy Astrophysical Phenomena, Energy (signal processing)
Abstract

High-energy neutrino emission has been predicted for several short-lived astrophysical transients including gamma-ray bursts (GRBs), core-collapse supernovae with choked jets, and neutron star mergers. IceCube's optical and x-ray follow-up program searches for such transient sources by looking for two or more muon neutrino candidates in directional coincidence and arriving within 100 s. The measured rate of neutrino alerts is consistent with the expected rate of chance coincidences of atmospheric background events and no likely electromagnetic counterparts have been identified in Swift follow-up observations. Here, we calculate generic bounds on the neutrino flux of short-lived transient sources. Assuming an E-2.5 neutrino spectrum, we find that the neutrino flux of rare sources, like long gamma-ray bursts, is constrained to, 0, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2018
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23. Measurement of Atmospheric Neutrino Oscillations at 6–56 GeV with IceCube DeepCore

Author

P. Schlunder, R. Hellauer, Sally Robertson, S. De Ridder, F. Bos, Dirk Lennarz, Gisela Anton, M. E. Huber, Allan Hallgren, L. Classen, T. Kittler, S. Flis, M. Labare, J. Werthebach, K. Clark, A. Wallace, Darren Grant, Sarah Nowicki, G. H. Collin, Piotr Kalaczyński, C. Pérez de los Heros, F. D. Wandler, M. Brenzke, J. P. A. M. de André, L. Gerhardt, Minjin Jeong, M. Vehring, D. F. Cowen, J. P. Barron, S. Yoshida, Stijn Vanheule, Maryon Ahrens, Frederik Tenholt, M. Rameez, M. Medici, A. Waza, Philipp Eller, Thomas Meures, E. Woolsey, G. Binder, P. B. Price, T. O. B. Schmidt, Francis Halzen, Joshua Pepper, Karim Ghorbani, S. Coenders, K. Helbing, Christian Spiering, Sarah Mancina, Spencer Axani, K. Jero, Joshua A. Wood, I. Ansseau, T. R. Wood, Kurt Woschnagg, Elisa Bernardini, A. Terliuk, Justin Vandenbroucke, Paul Evenson, S. Schöneberg, H. Dembinski, Frank McNally, Chunfai Tung, Klas Hultqvist, J. Kiryluk, J. Felde, Xinhua Bai, K. Andeen, E. Jacobi, A. Kyriacou, D. Berley, Benjamin Hokanson-Fasig, W. Giang, J. L. Lanfranchi, P. Nakarmi, Carlos Arguelles, Janet Conrad, Dmitry Chirkin, F. Bradascio, A. Obertacke Pollmann, I. Al Samarai, J. L. Kelley, Alexander Kappes, C. Walck, Jessie Micallef, R. Cross, M. Rongen, Joshua Hignight, K. Krings, M. S. Sutherland, M. Börner, Markus Ahlers, S. Tilav, U. Katz, E. Pinat, K. Rawlins, George Japaridze, Roger Moore, Ramesh Koirala, Dennis Soldin, A. Christov, William Luszczak, Frederik Hermann Lauber, Jenni Adams, S. Hickford, D. J. Koskinen, Simona Toscano, M. Kauer, M. Zoll, S. Westerhoff, James Madsen, J. Bourbeau, E. Blaufuss, Lu Lu, Donglian Xu, Yiqian Xu, J. Tatar, Samvel Ter-Antonyan, D. Bose, R. G. Stokstad, M. J. Larson, Seongjin In, Hermann Kolanoski, Elisa Resconi, M. N. Tobin, M. Song, T. L. Carver, Mike Richman, J. Becker Tjus, A. Stasik, J. P. Dumm, Subir Sarkar, E. Cheung, M. Usner, T. Palczewski, Dirk Ryckbosch, M. Day, C. Kopper, Teresa Montaruli, T. Karg, R. Maunu, T. Kuwabara, E. Vogel, M. Stamatikos, J. Braun, T. Stezelberger, Jan Soedingrekso, B. Eberhardt, Kendall Mahn, Jae Yool Kim, J. Stachurska, N. L. Strotjohann, T. Menne, L. Rädel, J. Casey, S. Schoenen, D. Bindig, A. Franckowiak, D. Heereman, B. Relethford, P. Peiffer, Konstancja Satalecka, Theo Glauch, A. Goldschmidt, Gerald Przybylski, Z. Griffith, Marjon Moulai, S. Kunwar, K. Meagher, Jay Gallagher, J. C. Díaz-Vélez, Azadeh Keivani, C. F. Turley, G. Krückl, Matthias Vraeghe, N. Kurahashi, B. J. Whelan, Todor Stanev, G. Tešić, T. Anderson, E. Friedman, A. Olivas, Delia Tosi, Mirco Hunnefeld, C. Wendt, F. Huang, M. Dunkman, G. de Wasseige, J. Stettner, D. R. Nygren, J. Lünemann, C. De Clercq, J. J. Beatty, Tianlu Yuan, K. Hoshina, M. Lesiak-Bzdak, R. Hoffmann, Glenn Spiczak, G. Momenté, M. Tselengidou, M. G. Aartsen, Thomas K. Gaisser, G. B. Yodh, U. Naumann, K. H. Becker, T. Kintscher, Marsha J. Wolf, E. Unger, Javier Gonzalez, D. Rysewyk, Giorgio Maggi, K. Wiebe, Marek Kowalski, David A. Williams, B. J. P. Jones, T. Sälzer, Markus Ackermann, A. Stößl, H. Bagherpour, Olga Botner, Reina H. Maruyama, M. Relich, V. Baum, Chris Weaver, G. Merino, Kirill Filimonov, M. Kroll, N. Wandkowsky, K. D. de Vries, H. Dujmovic, J. P. Koschinsky, R. Nahnhauer, L. Schumacher, Carsten Rott, D. V. Pankova, M. Casier, M. Leuermann, L. Wills, Surujhdeo Seunarine, G. Kohnen, J. P. Yanez, A. Steuer, Juanan Aguilar, N. van Eijndhoven, J. Kunnen, S. Böser, R. C. Bay, A. Ishihara, D. Z. Besson, Xianwu Xu, Damian Pieloth, J. Sandroos, D. Altmann, Austin Schneider, Ali Kheirandish, J. Auffenberg, W. Van Driessche, G. W. Sullivan, Jannes Brostean-Kaiser, T. Fuchs, L. Köpke, Albrecht Karle, L. Brayeur, I. Taboada, Segev BenZvi, Spencer Klein, Kara Hoffman, Won Nam Kang, Hershal Pandya, Wolfgang Rhode, J. J. DeLaunay, G. Neer, Tim Ruhe, J. van Santen, Kael Hanson, M. Plum, S. Bron, Steven W. Barwick, Maximilian Meier, Paolo Desiati, T. Ehrhardt, Alexander Sandrock, D. Hebecker, K. Mase, Andrea Turcati, Stijn Blot, C. Haack, M. J. Weiss, R. Reimann, S. Kopper, Christopher Wiebusch, Christian Bohm, Aongus O'Murchadha, Christoph Raab, G. C. Hill, Bunheng Ty, D. Seckel, S. Fahey, S. Miarecki, A. R. Fazely, Tyce DeYoung, P. A. Toale, Immacolata Carmen Rea, B. Eichmann, H.-P. Bretz, M. Kim, L. Wille, S. E. Sanchez Herrera, Hans Niederhausen, V. di Lorenzo, C. Finley, A. Burgman, Qinrui Liu, T. Glüsenkamp, M. Wallraff, Physics, Elementary Particle Physics, Vriendenkring VUB, Faculty of Sciences and Bioengineering Sciences, Massachusetts Institute of Technology. Department of Physics, Arguelles Delgado, Carlos A, Axani, Spencer Nicholas, Collin, G. H., Conrad, Janet Marie, Moulai, Marjon H., Al Samarai, Imen, Bron, Stéphanie, Carver, Tessa, Christov, Asen, and Montaruli, Teresa

Subjects
interaction [cosmic radiation], Physics::Instrumentation and Detectors, Solar neutrino, General Physics and Astronomy, 01 natural sciences, 7. Clean energy, High Energy Physics - Experiment, IceCube, Subatomär fysik, High Energy Physics - Experiment (hep-ex), Observatory, Subatomic Physics, TOOL, Physics, oscillation [neutrino], Astrophysics::Instrumentation and Methods for Astrophysics, atmosphere [neutrino], threshold [energy], mass difference [neutrino], ddc, observatory, Neutrino detector, Physique des particules élémentaires, Astrophysics::Earth and Planetary Astrophysics, Neutrino, Particle physics, cosmic radiation [neutrino], accelerator, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, ddc:500.2, Physics and Astronomy(all), IceCube Neutrino Observatory, Physics and Astronomy (all), 0103 physical sciences, neutrino/mu, ddc:530, energy: high [neutrino], 010306 general physics, Neutrino oscillation, Astroparticle physics, 010308 nuclear & particles physics, ICE, High Energy Physics::Phenomenology, Astronomy, Solar neutrino problem, Physics and Astronomy, 13. Climate action, mass [neutrino], High Energy Physics::Experiment, SYSTEM, mixing angle [neutrino], experimental results
Abstract

We present a measurement of the atmospheric neutrino oscillation parameters using three years of data from the IceCube Neutrino Observatory. The DeepCore infill array in the center of IceCube enables the detection and reconstruction of neutrinos produced by the interaction of cosmic rays in Earth's atmosphere at energies as low as ∼5 GeV. That energy threshold permits measurements of muon neutrino disappearance, over a range of baselines up to the diameter of the Earth, probing the same range of L/Eν as long-baseline experiments but with substantially higher-energy neutrinos. This analysis uses neutrinos from the full sky with reconstructed energies from 5.6 to 56 GeV. We measure Δm322=2.31-0.13+0.11×10-3 eV2 and sin2θ23=0.51-0.09+0.07, assuming normal neutrino mass ordering. These results are consistent with, and of similar precision to, those from accelerator- and reactor-based experiments., 0, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2018
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24. Measurement of the $$\nu _{\mu }$$ <math><msub><mi>ν</mi><mi>μ</mi></msub></math> energy spectrum with IceCube-79

Author

M. G. Aartsen, M. Ackermann, J. Adams, J. A. Aguilar, M. Ahlers, M. Ahrens, I. Al Samarai, D. Altmann, K. Andeen, T. Anderson, I. Ansseau, G. Anton, M. Archinger, C. Argüelles, J. Auffenberg, S. Axani, H. Bagherpour, X. Bai, S. W. Barwick, V. Baum, R. Bay, J. J. Beatty, J. Becker Tjus, K.-H. Becker, S. BenZvi, D. Berley, E. Bernardini, D. Z. Besson, G. Binder, D. Bindig, E. Blaufuss, S. Blot, C. Bohm, M. Börner, F. Bos, D. Bose, S. Böser, O. Botner, F. Bradascio, J. Braun, L. Brayeur, H.-P. Bretz, S. Bron, A. Burgman, T. Carver, M. Casier, E. Cheung, D. Chirkin, A. Christov, K. Clark, L. Classen, S. Coenders, G. H. Collin, J. M. Conrad, D. F. Cowen, R. Cross, M. Day, J. P. A. M. de André, C. De Clercq, E. del Pino Rosendo, H. Dembinski, S. De Ridder, P. Desiati, K. D. de Vries, G. de Wasseige, M. de With, T. DeYoung, J. C. Díaz-Vélez, V. di Lorenzo, H. Dujmovic, J. P. Dumm, M. Dunkman, B. Eberhardt, T. Ehrhardt, B. Eichmann, P. Eller, S. Euler, P. A. Evenson, S. Fahey, A. R. Fazely, J. Feintzeig, J. Felde, K. Filimonov, C. Finley, S. Flis, C.-C. Fösig, A. Franckowiak, E. Friedman, T. Fuchs, T. K. Gaisser, J. Gallagher, L. Gerhardt, K. Ghorbani, W. Giang, L. Gladstone, T. Glauch, T. Glüsenkamp, A. Goldschmidt, J. G. Gonzalez, D. Grant, Z. Griffith, C. Haack, A. Hallgren, F. Halzen, E. Hansen, T. Hansmann, K. Hanson, D. Hebecker, D. Heereman, K. Helbing, R. Hellauer, S. Hickford, J. Hignight, G. C. Hill, K. D. Hoffman, R. Hoffmann, K. Hoshina, F. Huang, M. Huber, K. Hultqvist, S. In, A. Ishihara, E. Jacobi, G. S. Japaridze, M. Jeong, K. Jero, B. J. P. Jones, W. Kang, A. Kappes, T. Karg, A. Karle, U. Katz, M. Kauer, A. Keivani, J. L. Kelley, A. Kheirandish, J. Kim, M. Kim, T. Kintscher, J. Kiryluk, T. Kittler, S. R. Klein, G. Kohnen, R. Koirala, H. Kolanoski, R. Konietz, L. Köpke, C. Kopper, S. Kopper, D. J. Koskinen, M. Kowalski, K. Krings, M. Kroll, G. Krückl, C. Krüger, J. Kunnen, S. Kunwar, N. Kurahashi, T. Kuwabara, A. Kyriacou, M. Labare, J. L. Lanfranchi, M. J. Larson, F. Lauber, D. Lennarz, M. Lesiak-Bzdak, M. Leuermann, L. Lu, J. Lünemann, J. Madsen, G. Maggi, K. B. M. Mahn, S. Mancina, R. Maruyama, K. Mase, R. Maunu, F. McNally, K. Meagher, M. Medici, M. Meier, T. Menne, G. Merino, T. Meures, S. Miarecki, J. Micallef, G. Momenté, T. Montaruli, M. Moulai, R. Nahnhauer, U. Naumann, G. Neer, H. Niederhausen, S. C. Nowicki, D. R. Nygren, A. Obertacke Pollmann, A. Olivas, A. O’Murchadha, T. Palczewski, H. Pandya, D. V. Pankova, P. Peiffer, Ö. Penek, J. A. Pepper, C. Pérez de los Heros, D. Pieloth, E. Pinat, P. B. Price, G. T. Przybylski, M. Quinnan, C. Raab, L. Rädel, M. Rameez, K. Rawlins, R. Reimann, B. Relethford, M. Relich, E. Resconi, W. Rhode, M. Richman, B. Riedel, S. Robertson, M. Rongen, C. Rott, T. Ruhe, D. Ryckbosch, D. Rysewyk, L. Sabbatini, S. E. Sanchez Herrera, A. Sandrock, J. Sandroos, S. Sarkar, K. Satalecka, P. Schlunder, T. Schmidt, S. Schoenen, S. Schöneberg, L. Schumacher, D. Seckel, S. Seunarine, D. Soldin, M. Song, G. M. Spiczak, C. Spiering, J. Stachurska, T. Stanev, A. Stasik, J. Stettner, A. Steuer, T. Stezelberger, R. G. Stokstad, A. Stößl, R. Ström, N. L. Strotjohann, G. W. Sullivan, M. Sutherland, H. Taavola, I. Taboada, J. Tatar, F. Tenholt, S. Ter-Antonyan, A. Terliuk, G. Tešić, S. Tilav, P. A. Toale, M. N. Tobin, S. Toscano, D. Tosi, M. Tselengidou, C. F. Tung, A. Turcati, E. Unger, M. Usner, J. Vandenbroucke, N. van Eijndhoven, S. Vanheule, M. van Rossem, J. van Santen, M. Vehring, M. Voge, E. Vogel, M. Vraeghe, C. Walck, A. Wallace, M. Wallraff, N. Wandkowsky, A. Waza, Ch. Weaver, M. J. Weiss, C. Wendt, S. Westerhoff, B. J. Whelan, S. Wickmann, K. Wiebe, C. H. Wiebusch, L. Wille, D. R. Williams, L. Wills, M. Wolf, T. R. Wood, E. Woolsey, K. Woschnagg, D. L. Xu, X. W. Xu, Y. Xu, J. P. Yanez, G. Yodh, S. Yoshida, and M. Zoll

Subjects
Astrophysics::High Energy Astrophysical Phenomena, lcsh:QB460-466, lcsh:QC770-798, lcsh:Astrophysics, lcsh:Nuclear and particle physics. Atomic energy. Radioactivity, High Energy Physics::Experiment
Abstract

IceCube is a neutrino observatory deployed in the glacial ice at the geographic South Pole. The $$\nu _\mu $$ νμ energy unfolding described in this paper is based on data taken with IceCube in its 79-string configuration. A sample of muon neutrino charged-current interactions with a purity of 99.5% was selected by means of a multivariate classification process based on machine learning. The subsequent unfolding was performed using the software Truee. The resulting spectrum covers an E$$_\nu $$ ν -range of more than four orders of magnitude from 125 GeV to 3.2 PeV. Compared to the Honda atmospheric neutrino flux model, the energy spectrum shows an excess of more than $$1.9\,\sigma $$ 1.9σ in four adjacent bins for neutrino energies $$E_\nu \ge 177.8\,\text {TeV}$$ Eν≥177.8TeV . The obtained spectrum is fully compatible with previous measurements of the atmospheric neutrino flux and recent IceCube measurements of a flux of high-energy astrophysical neutrinos.

Published
2017

25. PINGU: a vision for neutrino and particle physics at the South Pole

Author

A. Olivas, F. Huang, G. Neer, S. Euler, J. van Santen, M. Day, Kael Hanson, Janet Conrad, Hrvoje Dujmovic, Ignacio Taboada, Steven W. Barwick, Christian Bohm, D. Hebecker, Aongus O'Murchadha, Segev BenZvi, R. Cross, M. Wolf, M. Jurkovic, M. Rongen, M. Kauer, B. Relethford, Christian Spiering, Spencer Klein, Konstancja Satalecka, M. Song, T. L. Carver, Mike Richman, Maximilian Meier, Thomas Meures, Christoph Raab, Paolo Desiati, George Japaridze, M. Schimp, G. Krückl, P. Schlunder, Hermann Kolanoski, B. Hansmann, Roger Moore, G. C. Hill, E. Friedman, D. Tosi, H. Taavola, J. Lünemann, L. Brayeur, Sally Robertson, M. Kroll, S. Hickford, A. Meli, Kara Hoffman, K. D. de Vries, T. Ehrhardt, N. van Eijndhoven, Justin Vandenbroucke, M. Leuermann, E. Blaufuss, D. J. Boersma, K. Mase, Elisa Resconi, K. Hoshina, C. Krüger, Kurt Woschnagg, Paul Evenson, D. Seckel, S. Fahey, Sebastian Böser, M. Kowalski, G. H. Collin, C. Haack, M. J. Weiss, A. R. Fazely, Tyce DeYoung, P. A. Toale, S. Márka, M. Labare, U. Naumann, D. Berley, W. Giang, M. Quinnan, C. Kopper, J. Braun, T. Kittler, S. Flis, Glenn Spiczak, G. Golup, Gisela Anton, M. Dunkman, J. L. Lanfranchi, R. Reimann, Imre Bartos, Stijn Blot, K. Krings, M. Glagla, Karim Ghorbani, S. Seunarine, E. Pinat, Dmitry Chirkin, L. Mohrmann, R. Hoffmann, S. Kopper, Antonio Palazzo, Simona Toscano, M. Voge, Spencer Axani, M. Mandelartz, S. Coenders, T. R. Wood, S. C. Nowicki, T. C. Arlen, G. Merino, Wolfgang Rhode, N. Wandkowsky, Alexander Kappes, A. Christov, Minjin Jeong, J. L. Kelley, S. In, L. Gladstone, G. Karagiorgi, S. Mandalia, R. Koirala, Donglian Xu, R. Nahnhauer, Carlos Arguelles, S. Schoenen, J. J. Beatty, K. Abraham, L. Wills, Olga Botner, S. Miarecki, Christopher Wiebusch, J. Feintzeig, D. Heereman, A. Bernhard, M. Lesiak-Bzdak, Darren Grant, Juanan Aguilar, K. Wiebe, Azadeh Keivani, A. Haj Ismail, J. Kiryluk, F. Bos, Teppei Katori, K. H. Becker, E. Unger, D. Z. Besson, F. McNally, V. Baum, Francis Halzen, D. R. Nygren, Aya Ishihara, D. Rysewyk, Subir Sarkar, Allan Hallgren, D. V. Pankova, L. Classen, J. Haugen, K. Rawlins, I. Ansseau, M. J. Larson, A. Franckowiak, Marjon Moulai, S. Yoshida, M. Casier, B. Riedel, J. P. A. M. de André, M. Bissok, K. Jero, A. Stößl, A. Terliuk, E. Jacobi, M. G. Aartsen, S. Wickmann, J. Auffenberg, T. Stezelberger, T. Hansmann, G. W. Sullivan, M. H. Shaevitz, Reina H. Maruyama, A. Turcati, R. Maunu, J. Kunnen, Damian Pieloth, Ali Kheirandish, B. Eichmann, H. Dembinski, C. Walck, James Madsen, M. S. Kim, James Pinfold, Michael Sutherland, H.-P. Bretz, A. Stasik, N. L. Strotjohann, Lu Lu, Sarah Mancina, S. De Ridder, B. J. P. Jones, M. Stahlberg, L. Schumacher, A. Steuer, D. Bindig, M. van Rossem, Gerald Przybylski, T. Fuchs, Y. Xu, M. N. Tobin, E. Hansen, M. E. Huber, E. Pino del Rosendo, M. Börner, Klas Hultqvist, Z. Griffith, R. C. Bay, J. C. Díaz-Vélez, D. Bose, J. P. Dumm, M. Relich, K. Meagher, T. Karg, Ch. Weaver, L. Gerhardt, Maryon Ahrens, O. Kalekin, K. Andeen, Teresa Montaruli, P. Sandstrom, Frederik Tenholt, M. Rameez, M. Archinger, M. Medici, Kendall Mahn, Frederik Hermann Lauber, H. Niederhausen, L. Köpke, T. Palczewski, Julian Kemp, M. Zoll, G. Kohnen, Carsten Rott, G. Maggi, J. Tatar, S. Westerhoff, Albrecht Karle, M. Wallraff, Xianwu Xu, J. Sandroos, D. Altmann, P. Berghaus, T. Anderson, B. Eberhardt, C. De Clercq, C. Pérez de los Heros, R. Ström, G. Tešić, T. Kuwabara, Kirill Filimonov, D. J. Koskinen, Ö. Penek, S. Söldner-Rembold, Dirk Lennarz, Thorsten Glusenkamp, D. Soldin, S. Schöneberg, Z. Márka, K. Helbing, U. Katz, L. Rädel, Alexander Burgman, Hiroyuki Tanaka, Jenni Adams, Akimichi Taketa, J. Leuner, R. G. Stokstad, Killian Holzapfel, Chris Wendt, C.-C. Fösig, R. Konietz, M. Vehring, J. M. LoSecco, Joshua Hignight, H. Pandya, T. Kintscher, Javier Gonzalez, C. B. Krauss, E. Woolsey, G. Binder, Joshua Pepper, P. B. Price, D. Ryckbosch, Markus Ackermann, N. Kurahashi, B. J. Whelan, Todor Stanev, R. Hellauer, Dawn Williams, G. de Wasseige, Elisa Bernardini, M. Tselengidou, Thomas K. Gaisser, G. B. Yodh, J. Becker Tjus, J. Veenkamp, A. Goldschmidt, Troels Petersen, S. Kunwar, S. Wren, L. Sabbatini, T. Ruhe, S. Tilav, J. P. Yanez, T. Schmidt, L. Wille, S. E. Sanchez Herrera, E. Cheung, M. Usner, V. di Lorenzo, T. Menne, C. Finley, A. Wallace, K. Clark, D. F. Cowen, Stijn Vanheule, Philipp Eller, A. Sandrock, J. Felde, Xinhua Bai, A. Obertacke Pollmann, Markus Ahlers, M. Vraeghe, J. J. Evans, Samvel Ter-Antonyan, Jay Gallagher, Faculty of Sciences and Bioengineering Sciences, Physics, Vriendenkring VUB, and Elementary Particle Physics

Subjects
Physics - Instrumentation and Detectors, Physics::Instrumentation and Detectors, mixing [neutrino], atmospheric neutrinos, IceCube Neutrino Observatory, neutrino oscillations, PINGU, Nuclear and High Energy Physics, pole, 7. Clean energy, 01 natural sciences, IceCube, High Energy Physics - Experiment, Observatory, Physics, solar [WIMP], precision measurement, Astrophysics::Instrumentation and Methods for Astrophysics, oscillation [neutrino], solar [dark matter], atmosphere [neutrino], threshold [energy], mass difference [neutrino], observatory, High Energy Physics - Phenomenology, Upgrade, Neutrino detector, upgrade, Neutrino, KM3NET, performance, Particle physics, supernova [neutrino], particle identification [neutrino/tau], Astrophysics::High Energy Astrophysical Phenomena, SUPERNOVA DETECTION, 0103 physical sciences, OSCILLATIONS, mass: low [dark matter], unitarity, ddc:530, 010306 general physics, Neutrino oscillation, 010308 nuclear & particles physics, Astronomy, sensitivity, KM3NeT, Physics and Astronomy, mass [neutrino], beam [neutrino], High Energy Physics::Experiment, galaxy, ATMOSPHERIC NEUTRINOS, MATTER, SYSTEM, Lepton, mixing angle [neutrino], experimental results
Abstract

The Precision IceCube Next Generation Upgrade (PINGU) is a proposed low-energy in-fill extension to the IceCube Neutrino Observatory. With detection technology modeled closely on the successful IceCube example, PINGU will provide a 6Mton effective mass for neutrino detection with an energy threshold of a few GeV. With an unprecedented sample of over 60,000 atmospheric neutrinos per year in this energy range, PINGU will make highly competitive measurements of neutrino oscillation parameters in an energy range over an order of magnitude higher than long-baseline neutrino beam experiments. PINGU will measure the mixing parameters $\theta_{\rm 23}$ and $\Delta m^2_{\rm 32}$, including the octant of $\theta_{\rm 23}$ for a wide range of values, and determine the neutrino mass ordering at $3\sigma$ median significance within 4 years of operation. PINGU's high precision measurement of the rate of ${\nu_\tau}$ appearance will provide essential tests of the unitarity of the $3\times 3$ PMNS neutrino mixing matrix. PINGU will also improve the sensitivity of searches for low mass dark matter in the Sun, use neutrino tomography to directly probe the composition of the Earth's core, and improve IceCube's sensitivity to neutrinos from Galactic supernovae. Reoptimization of the PINGU design has permitted substantial reduction in both cost and logistical requirements while delivering performance nearly identical to configurations previously studied. This document summarizes the results of detailed studies described in a more comprehensive document to be released soon., Comment: 28 pages, 10 figures, submitted to J. Phys. G

Published
2017

26. Search for sterile neutrino mixing using three years of IceCube DeepCore data

Author

Janet Conrad, M. Rongen, M. S. Sutherland, M. Kauer, G. Merino, D. Bose, Francis Halzen, J. P. Dumm, I. Ansseau, A. Terliuk, E. Vogel, Christian Bohm, B. Eberhardt, Aongus O'Murchadha, Christoph Raab, Jenni Adams, R. Nahnhauer, D. Berley, G. C. Hill, Juanan Aguilar, Hrvoje Dujmovic, L. Gladstone, C. Krüger, D. Seckel, S. Fahey, S. Miarecki, E. Jacobi, Tyce DeYoung, R. Maunu, A. Ishihara, P. A. Toale, Sander Vanheule, T. Kuwabara, T. Karg, Ch. Weaver, S. Hickford, R. G. Stokstad, A. Kyriacou, Joonghan Kim, J. Feintzeig, K. Mase, Minjin Jeong, G. Tešić, Tim Ruhe, E. Friedman, C.-C. Fösig, Darren Grant, N. L. Strotjohann, I. Al Samarai, A. Karle, J. Becker Tjus, Karim Ghorbani, Sarah Nowicki, C. H. Wiebusch, J. P. A. M. de André, K. Filimonov, Spencer Axani, M. Leuermann, G. Kohnen, J. P. Yanez, G. Maggi, Alexander Burgman, M. Kroll, C. Walck, D. Z. Besson, H.-P. Bretz, T. Menne, M. J. Larson, G. Krückl, Frank McNally, Chunfai Tung, Carlos Arguelles, E. V. Hansen, D. Tosi, J. Stachurska, C. Pérez de los Heros, Jessie Micallef, Z. Griffith, M. Kowalski, A. Stasik, R. Konietz, G.M. Spiczak, Joakim Sandroos, Azadeh Keivani, Konstancja Satalecka, J. J. Beatty, Joanna Kiryluk, K. Meagher, M. Day, Dirk Lennarz, M. Zoll, A. Franckowiak, Marjon Moulai, H. Dembinski, K. Rawlins, Theo Glauch, S. Westerhoff, Gerald Przybylski, D. Rysewyk, M. Quinnan, D. Soldin, M. Dunkman, K. Clark, S. Yoshida, T. Hansmann, A. Stößl, B. J. Whelan, Christian Spiering, Thorsten Glusenkamp, Reina H. Maruyama, David R. Williams, Todor Stanev, Claudio Kopper, C. Wendt, K. D. Hoffman, Justin Vandenbroucke, G. W. Sullivan, S. Schöneberg, James E. Braun, James Madsen, Lu Lu, L. Schumacher, M. Casier, E. del Pino Rosendo, W. Giang, G. de Wasseige, J. L. Lanfranchi, J. Lünemann, Subir Sarkar, R. Hoffmann, Martin Wolf, R. C. Bay, Olga Botner, J. Tatar, N. van Eijndhoven, Gisela Anton, Juan Carlos Diaz-Velez, M. Archinger, K. Helbing, Thomas Meures, V. Baum, D.F. Cowen, M. Tselengidou, R. Cross, Andrea Turcati, Teresa Montaruli, J. Stettner, Thomas K. Gaisser, G. B. Yodh, L. Sabbatini, P. Peiffer, J. van Santen, Stijn Blot, K. D. de Vries, K. Hoshina, M. Mandelartz, Kendall Mahn, U. Katz, T. Kintscher, Gary Binder, A. Sandrock, George Japaridze, S. Tilav, B. J. P. Jones, A. R. Fazely, J. L. Kelley, E. Woolsey, M. E. Huber, Joshua Pepper, J. S. Gallagher, M. Richman, K. Wiebe, M. Tobin, J. Hignight, U. Naumann, M. Lesiak-Bzdak, Seongjin In, F. Lauber, A. Olivas, E. Pinat, Hermann Kolanoski, E. Unger, Elisa Resconi, Elisa Bernardini, Simona Toscano, C. De Clercq, F. Tenholt, Richard G. Strom, Philipp Eller, Kael Hanson, Carsten Rott, Markus Ackermann, S. Bron, T. Fuchs, S. W. Barwick, Maximilian Meier, Segev BenZvi, Paolo Desiati, A. Goldschmidt, S. Kunwar, F. Huang, Xianwu Xu, D. Altmann, Timothy W. Schmidt, K.-H. Becker, Yiqian Xu, J. Felde, S. Seunarine, E. Cheung, A. Steuer, M. Usner, A. Kheirandish, Dirk Ryckbosch, A. Obertacke Pollmann, F. Bos, J. G. Gonzalez, P. Schlunder, Hershal Pandya, Markus Ahlers, Wolfgang Rhode, V. di Lorenzo, Allan Hallgren, T. Palczewski, S. Schoenen, Sandro Kopper, C. Finley, D. Heereman, Samvel Ter-Antonyan, L. Brayeur, Naoko Kurahashi, I. Taboada, Dustin Hebecker, T. Anderson, K. Jero, S. R. Klein, M. G. Aartsen, Thomas Ehrhardt, Ramesh Koirala, H. Taavola, E. Blaufuss, K. Woschnagg, L. Classen, N. Wandkowsky, M. Relich, M. Wallraff, M. S. Kim, L. Wills, M. Voge, K. Krings, Woosik Kang, S. De Ridder, Benedikt Riedel, M. van Rossem, L. Gerhardt, Maryon Ahrens, M. Rameez, S. Euler, M. Medici, S. Coenders, M. Labare, J. Kunnen, D. V. Pankova, D. R. Nygren, Damian Pieloth, L. Wille, S. E. Sanchez Herrera, S. Wickmann, J. Auffenberg, Hans Niederhausen, A. Wallace, X. Bai, G. Neer, L. Köpke, Da Xu, R. Hellauer, G. Momenté, M. Vehring, M. Song, T. L. Carver, Sally Robertson, Sebastian Böser, P. B. Price, A. Waza, C. Haack, M. J. Weiss, T. Kittler, S. Flis, T. R. Wood, R. Reimann, Matthias Vraeghe, Sarah Mancina, Paul Evenson, M. Börner, Klas Hultqvist, K. Andeen, D. J. Koskinen, Björn Eichmann, Ö. Penek, L. Rädel, Gabriel Collin, Dmitry Chirkin, Alexander Kappes, A. Christov, B. Relethford, Daniel Bindig, T. Stezelberger, Physics, Elementary Particle Physics, Faculty of Sciences and Bioengineering Sciences, and Vriendenkring VUB

Subjects
FLUX, Sterile neutrino, Particle physics, Physics and Astronomy (miscellaneous), Physics::Instrumentation and Detectors, Solar neutrino, Astrophysics::High Energy Astrophysical Phenomena, FOS: Physical sciences, 01 natural sciences, High Energy Physics - Experiment, OSCILLATION EXPERIMENTS, High Energy Physics - Experiment (hep-ex), High Energy Physics - Phenomenology (hep-ph), 0103 physical sciences, TRACK RECONSTRUCTION, ddc:530, 010306 general physics, Neutrino oscillation, Physics, 010308 nuclear & particles physics, High Energy Physics::Phenomenology, Astronomy, Solar neutrino problem, LINE-EXPERIMENT-SIMULATOR, MODEL, High Energy Physics - Phenomenology, Neutrino detector, Physics and Astronomy, Measurements of neutrino speed, High Energy Physics::Experiment, Neutrino astronomy, Neutrino
Abstract

Physical review / D 95(11), 112002(2017). doi:10.1103/PhysRevD.95.112002, We present a search for a light sterile neutrino using three years of atmospheric neutrino data from the DeepCore detector in the energy range of approximately 10–60 GeV. DeepCore is the low-energy subarray of the IceCube Neutrino Observatory. The standard three-neutrino paradigm can be probed by adding an additional light (Δm$^{2}_{41}$ ∼ 1 eV2) sterile neutrino. Sterile neutrinos do not interact through the standard weak interaction and, therefore, cannot be directly detected. However, their mixing with the three active neutrino states leaves an imprint on the standard atmospheric neutrino oscillations for energies below 100 GeV. A search for such mixing via muon neutrino disappearance is presented here. The data are found to be consistent with the standard three-neutrino hypothesis. Therefore, we derive limits on the mixing matrix elements at the level of $|U_{μ4}|^{2}, Published by APS, Woodbury, NY

Published
2017

27. Measurement of the multi-TeV neutrino interaction cross-section with IceCube using Earth absorption

Author

M. G. Aartsen, G. C. Hill, A. Kyriacou, S. Robertson, A. Wallace, B. J. Whelan, M. Ackermann, E. Bernardini, S. Blot, F. Bradascio, H.-P. Bretz, J. Brostean-Kaiser, A. Franckowiak, E. Jacobi, T. Karg, T. Kintscher, S. Kunwar, R. Nahnhauer, K. Satalecka, C. Spiering, J. Stachurska, A. Stasik, N. L. Strotjohann, A. Terliuk, M. Usner, J. van Santen, J. Adams, H. Bagherpour, J. A. Aguilar, I. Ansseau, D. Heereman, K. Meagher, T. Meures, A. O’Murchadha, E. Pinat, C. Raab, M. Ahlers, D. J. Koskinen, M. J. Larson, M. Medici, M. Rameez, M. Ahrens, C. Bohm, J. P. Dumm, C. Finley, S. Flis, K. Hultqvist, C. Walck, M. Zoll, I. Al Samarai, S. Bron, T. Carver, A. Christov, T. Montaruli, D. Altmann, G. Anton, T. Glüsenkamp, U. Katz, T. Kittler, M. Tselengidou, K. Andeen, M. Plum, T. Anderson, J. J. DeLaunay, M. Dunkman, P. Eller, F. Huang, A. Keivani, J. L. Lanfranchi, D. V. Pankova, G. Tešic´, C. F. Turley, M. J. Weiss, C. Argüelles, S. Axani, G. H. Collin, J. M. Conrad, M. Moulai, J. Auffenberg, M. Brenzke, T. Glauch, C. Haack, P. Kalaczynski, J. P. Koschinsky, M. Leuermann, L. Rädel, R. Reimann, M. Rongen, T. Sälzer, S. Schoenen, L. Schumacher, J. Stettner, M. Vehring, E. Vogel, M. Wallraff, A. Waza, C. H. Wiebusch, X. Bai, J. P. Barron, W. Giang, D. Grant, C. Kopper, R. W. Moore, S. C. Nowicki, S. E. Sanchez Herrera, S. Sarkar, F. D. Wandler, C. Weaver, T. R. Wood, E. Woolsey, J. P. Yanez, S. W. Barwick, G. Yodh, V. Baum, S. Böser, V. di Lorenzo, B. Eberhardt, T. Ehrhardt, L. Köpke, G. Krückl, G. Momenté, P. Peiffer, J. Sandroos, A. Steuer, K. Wiebe, R. Bay, K. Filimonov, P. B. Price, K. Woschnagg, J. J. Beatty, J. Becker Tjus, F. Bos, B. Eichmann, M. Kroll, S. Schöneberg, F. Tenholt, K.-H. Becker, D. Bindig, K. Helbing, S. Hickford, R. Hoffmann, F. Lauber, U. Naumann, A. Obertacke Pollmann, D. Soldin, S. BenZvi, R. Cross, D. Berley, E. Blaufuss, E. Cheung, J. Felde, E. Friedman, R. Hellauer, K. D. Hoffman, R. Maunu, A. Olivas, T. Schmidt, M. Song, G. W. Sullivan, D. Z. Besson, G. Binder, S. R. Klein, S. Miarecki, T. Palczewski, J. Tatar, M. Börner, T. Fuchs, M. Hünnefeld, M. Meier, T. Menne, D. Pieloth, W. Rhode, T. Ruhe, A. Sandrock, P. Schlunder, J. Soedingrekso, J. Werthebach, D. Bose, H. Dujmovic, S. In, M. Jeong, W. Kang, J. Kim, C. Rott, O. Botner, A. Burgman, A. Hallgren, C. Pérez de los Heros, E. Unger, J. Bourbeau, J. Braun, J. Casey, D. Chirkin, M. Day, P. Desiati, J. C. Díaz-Vélez, S. Fahey, K. Ghorbani, Z. Griffith, F. Halzen, K. Hanson, B. Hokanson-Fasig, K. Hoshina, K. Jero, A. Karle, M. Kauer, J. L. Kelley, A. Kheirandish, Q. R. Liu, W. Luszczak, S. Mancina, F. McNally, G. Merino, A. Schneider, M. N. Tobin, D. Tosi, B. Ty, J. Vandenbroucke, N. Wandkowsky, C. Wendt, S. Westerhoff, L. Wille, M. Wolf, J. Wood, D. L. Xu, T. Yuan, L. Brayeur, M. Casier, C. De Clercq, K. D. de Vries, G. de Wasseige, J. Kunnen, J. Lünemann, G. Maggi, S. Toscano, N. van Eijndhoven, K. Clark, L. Classen, A. Kappes, S. Coenders, K. Krings, I. C. Rea, E. Resconi, A. Turcati, D. F. Cowen, J. P. A. M. de André, T. DeYoung, J. Hignight, D. Lennarz, K. B. M. Mahn, J. Micallef, G. Neer, D. Rysewyk, H. Dembinski, P. A. Evenson, T. K. Gaisser, J. G. Gonzalez, R. Koirala, H. Pandya, D. Seckel, T. Stanev, S. Tilav, S. De Ridder, M. Labare, D. Ryckbosch, W. Van Driessche, S. Vanheule, M. Vraeghe, M. de With, D. Hebecker, H. Kolanoski, A. R. Fazely, S. Ter-Antonyan, X. W. Xu, J. Gallagher, L. Gerhardt, A. Goldschmidt, D. R. Nygren, G. T. Przybylski, T. Stezelberger, R. G. Stokstad, A. Ishihara, M. Kim, T. Kuwabara, L. Lu, K. Mase, M. Relich, A. Stößl, S. Yoshida, G. S. Japaridze, B. J. P. Jones, J. Kiryluk, M. Lesiak-Bzdak, H. Niederhausen, Y. Xu, G. Kohnen, S. Kopper, P. Nakarmi, J. A. Pepper, P. A. Toale, D. R. Williams, M. Kowalski, N. Kurahashi, B. Relethford, M. Richman, L. Wills, J. Madsen, S. Seunarine, G. M. Spiczak, R. Maruyama, K. Rawlins, M. Sutherland, I. Taboada, C. F. Tung, M. Huber, M. G. Aartsen, G. C. Hill, A. Kyriacou, S. Robertson, A. Wallace, B. J. Whelan, M. Ackermann, E. Bernardini, S. Blot, F. Bradascio, H.-P. Bretz, J. Brostean-Kaiser, A. Franckowiak, E. Jacobi, T. Karg, T. Kintscher, S. Kunwar, R. Nahnhauer, K. Satalecka, C. Spiering, J. Stachurska, A. Stasik, N. L. Strotjohann, A. Terliuk, M. Usner, J. van Santen, J. Adams, H. Bagherpour, J. A. Aguilar, I. Ansseau, D. Heereman, K. Meagher, T. Meures, A. O’Murchadha, E. Pinat, C. Raab, M. Ahlers, D. J. Koskinen, M. J. Larson, M. Medici, M. Rameez, M. Ahrens, C. Bohm, J. P. Dumm, C. Finley, S. Flis, K. Hultqvist, C. Walck, M. Zoll, I. Al Samarai, S. Bron, T. Carver, A. Christov, T. Montaruli, D. Altmann, G. Anton, T. Glüsenkamp, U. Katz, T. Kittler, M. Tselengidou, K. Andeen, M. Plum, T. Anderson, J. J. DeLaunay, M. Dunkman, P. Eller, F. Huang, A. Keivani, J. L. Lanfranchi, D. V. Pankova, G. Tešic´, C. F. Turley, M. J. Weiss, C. Argüelles, S. Axani, G. H. Collin, J. M. Conrad, M. Moulai, J. Auffenberg, M. Brenzke, T. Glauch, C. Haack, P. Kalaczynski, J. P. Koschinsky, M. Leuermann, L. Rädel, R. Reimann, M. Rongen, T. Sälzer, S. Schoenen, L. Schumacher, J. Stettner, M. Vehring, E. Vogel, M. Wallraff, A. Waza, C. H. Wiebusch, X. Bai, J. P. Barron, W. Giang, D. Grant, C. Kopper, R. W. Moore, S. C. Nowicki, S. E. Sanchez Herrera, S. Sarkar, F. D. Wandler, C. Weaver, T. R. Wood, E. Woolsey, J. P. Yanez, S. W. Barwick, G. Yodh, V. Baum, S. Böser, V. di Lorenzo, B. Eberhardt, T. Ehrhardt, L. Köpke, G. Krückl, G. Momenté, P. Peiffer, J. Sandroos, A. Steuer, K. Wiebe, R. Bay, K. Filimonov, P. B. Price, K. Woschnagg, J. J. Beatty, J. Becker Tjus, F. Bos, B. Eichmann, M. Kroll, S. Schöneberg, F. Tenholt, K.-H. Becker, D. Bindig, K. Helbing, S. Hickford, R. Hoffmann, F. Lauber, U. Naumann, A. Obertacke Pollmann, D. Soldin, S. BenZvi, R. Cross, D. Berley, E. Blaufuss, E. Cheung, J. Felde, E. Friedman, R. Hellauer, K. D. Hoffman, R. Maunu, A. Olivas, T. Schmidt, M. Song, G. W. Sullivan, D. Z. Besson, G. Binder, S. R. Klein, S. Miarecki, T. Palczewski, J. Tatar, M. Börner, T. Fuchs, M. Hünnefeld, M. Meier, T. Menne, D. Pieloth, W. Rhode, T. Ruhe, A. Sandrock, P. Schlunder, J. Soedingrekso, J. Werthebach, D. Bose, H. Dujmovic, S. In, M. Jeong, W. Kang, J. Kim, C. Rott, O. Botner, A. Burgman, A. Hallgren, C. Pérez de los Heros, E. Unger, J. Bourbeau, J. Braun, J. Casey, D. Chirkin, M. Day, P. Desiati, J. C. Díaz-Vélez, S. Fahey, K. Ghorbani, Z. Griffith, F. Halzen, K. Hanson, B. Hokanson-Fasig, K. Hoshina, K. Jero, A. Karle, M. Kauer, J. L. Kelley, A. Kheirandish, Q. R. Liu, W. Luszczak, S. Mancina, F. McNally, G. Merino, A. Schneider, M. N. Tobin, D. Tosi, B. Ty, J. Vandenbroucke, N. Wandkowsky, C. Wendt, S. Westerhoff, L. Wille, M. Wolf, J. Wood, D. L. Xu, T. Yuan, L. Brayeur, M. Casier, C. De Clercq, K. D. de Vries, G. de Wasseige, J. Kunnen, J. Lünemann, G. Maggi, S. Toscano, N. van Eijndhoven, K. Clark, L. Classen, A. Kappes, S. Coenders, K. Krings, I. C. Rea, E. Resconi, A. Turcati, D. F. Cowen, J. P. A. M. de André, T. DeYoung, J. Hignight, D. Lennarz, K. B. M. Mahn, J. Micallef, G. Neer, D. Rysewyk, H. Dembinski, P. A. Evenson, T. K. Gaisser, J. G. Gonzalez, R. Koirala, H. Pandya, D. Seckel, T. Stanev, S. Tilav, S. De Ridder, M. Labare, D. Ryckbosch, W. Van Driessche, S. Vanheule, M. Vraeghe, M. de With, D. Hebecker, H. Kolanoski, A. R. Fazely, S. Ter-Antonyan, X. W. Xu, J. Gallagher, L. Gerhardt, A. Goldschmidt, D. R. Nygren, G. T. Przybylski, T. Stezelberger, R. G. Stokstad, A. Ishihara, M. Kim, T. Kuwabara, L. Lu, K. Mase, M. Relich, A. Stößl, S. Yoshida, G. S. Japaridze, B. J. P. Jones, J. Kiryluk, M. Lesiak-Bzdak, H. Niederhausen, Y. Xu, G. Kohnen, S. Kopper, P. Nakarmi, J. A. Pepper, P. A. Toale, D. R. Williams, M. Kowalski, N. Kurahashi, B. Relethford, M. Richman, L. Wills, J. Madsen, S. Seunarine, G. M. Spiczak, R. Maruyama, K. Rawlins, M. Sutherland, I. Taboada, C. F. Tung, and M. Huber

Abstract

type:text

Published
2017

28. Characterization of the atmospheric muon flux in IceCube

Author

C. Pérez de los Heros, M. Day, Julian Kemp, N. A. Stanisha, J. Feintzeig, Joshua Pepper, T. Anderson, K.-H. Becker, M. Schimp, Javier Gonzalez, P. Gretskov, Yiqian Xu, Matt Dunkman, Giorgio Maggi, T. Fischer-Wasels, M. Lesiak-Bzdak, P. Redl, A. Schukraft, C. De Clercq, E. Cheung, E. Middell, Elisa Bernardini, Dirk Ryckbosch, Sander Vanheule, Markus Ackermann, S. W. Barwick, L. Schulte, D. Heereman, Larissa Paul, F. Scheriau, Karim Ghorbani, M. J. Larson, Albrecht Karle, A. Schönwald, D. Altmann, G. Golup, R. Gaior, P. B. Price, N. Kurahashi, Todor Stanev, Dawn Williams, C. Wendt, G. Merino, N. Wandkowsky, L. Sabbatini, G. de Wasseige, Jenni Adams, Carlos Arguelles, K. Wiebe, T. O. B. Schmidt, S. Hickford, K. Schatto, G. Kohnen, Surujhdeo Seunarine, J. Miller, J. Leuner, R. G. Stokstad, Kirill Filimonov, R. Hoffmann, R. Nahnhauer, S. Tilav, C. Walck, R. Eagan, S. Schoenen, Delia Tosi, M. G. Aartsen, Juanan Aguilar, T. R. Wood, Kurt Woschnagg, Thorsten Glusenkamp, L. Classen, L. Mohrmann, S. Yoshida, Segev BenZvi, Thomas K. Gaisser, G. B. Yodh, M. Stamatikos, J. Pütz, E. A. Strahler, M. Relich, B. Christy, M. W. E. Smith, Paul Evenson, K. Rawlins, W. Huelsnitz, A. Ishihara, Spencer Klein, J. Becker Tjus, Anatoli Fedynitch, M. Kroll, A. Goldschmidt, Hermann Kolanoski, L. Brayeur, K. Helbing, James Madsen, N. van Eijndhoven, C. Haack, Dmitry Chirkin, B. Kaminsky, I. Taboada, J. Veenkamp, D. Z. Besson, K. D. de Vries, Alexander Kappes, S. Flis, Kara Hoffman, A. H. Cruz Silva, A. O'Murchadha, M. N. Tobin, B. Hansmann, A. Koob, Timo Karg, Gerald Przybylski, E. Beiser, A. Omairat, M. Zoll, M. Jurkovic, H.-P. Bretz, Killian Holzapfel, A. Christov, D. J. Koskinen, Carsten Rott, Teresa Montaruli, D. R. Nygren, M. Quinnan, Frank McNally, Hershal Pandya, K. Meagher, A. Stasik, Nathan Whitehorn, M. Bissok, Wolfgang Rhode, A. Meli, Kendall Mahn, M. Kauer, R. Konietz, E. Middlemas, G. Kroll, M. Glagla, P. Berghaus, Xianwu Xu, Marek Kowalski, J. Blumenthal, K. Hultqvist, B. Riedel, Joshua Hignight, J. Kläs, M. E. Huber, T. Menne, C. Bohm, Maria Tselengidou, S. Schöneberg, L. Rädel, L. Gerhardt, Darren Grant, Olga Botner, J. Kunnen, Ch. Weaver, M. Vehring, K. Hoshina, S. Böser, J. Auffenberg, C. Ha, Carl Pfendner, V. Baum, Chad Finley, A. Obertacke, Glenn Spiczak, Sarah Nowicki, Damian Pieloth, K. Mase, Ali Kheirandish, D. F. Cowen, J. P. A. M. de André, A. M. Brown, S. Euler, U. Naumann, Mohamed Rameez, E. Unger, M. Wallraff, T. Fuchs, L. Köpke, T. Stezelberger, M. Voge, S. M. Saba, A. Bernhard, D. Hellwig, Christian Spiering, Justin Vandenbroucke, Mike Richman, Kael Hanson, A. Olivas, M. Stahlberg, A. Haj Ismail, N. Buzinsky, A. Terliuk, S. Westerhoff, F. Huang, M. Usner, Justin Lanfranchi, M. Börner, J. Kiryluk, Martin Rongen, J. Casey, Matthias Vraeghe, L. Wille, P. O. Hulth, Hans Niederhausen, René Reimann, Björn Eichmann, H. Wissing, R. Hellauer, Paolo Desiati, Daniel Bindig, T. C. Arlen, R. Ström, X. Bai, Sally Robertson, Alexander Sandrock, B. J. Whelan, K. Clark, J. Felde, J. L. Kelley, Markus Ahlers, Samvel Ter-Antonyan, K. Krings, Ramesh Koirala, Dennis Soldin, H. Taavola, E. Blaufuss, D. J. Boersma, J. C. Davis, S. De Ridder, M. Labare, Maryon Ahrens, M. Medici, S. Coenders, Thomas Meures, N. L. Strotjohann, A. R. Fazely, E. Pinat, Donglian Xu, Subir Sarkar, R. Maunu, T. Kuwabara, J. C. Groh, C. Kopper, E. Jacobi, Joakim Sandroos, Azadeh Keivani, A. Homeier, M. Casier, Christopher Wiebusch, J. Daughhetee, J. P. Yanez, J. Lünemann, R. C. Bay, G. W. Sullivan, D. Berley, G. C. Hill, James E. Braun, Rezo Shanidze, Juan Carlos Diaz-Velez, M. Archinger, L. Gladstone, J. J. Beatty, D. Seckel, S. Fahey, S. Miarecki, J. C. Gallagher, Tyce DeYoung, P. A. Toale, M. Leuermann, J. Posselt, F. Bos, A. Stößl, Tim Ruhe, Allan Hallgren, Sandro Kopper, Reina H. Maruyama, M. Schmitz, K. Jero, Sofia Vallecorsa, D. Hebecker, Matthias Wolf, Thomas Ehrhardt, Andrea Turcati, J. van Santen, H. G. Sander, Gary Binder, Axel Groß, George Japaridze, Seongjin In, Elisa Resconi, M. S. Sutherland, G. Tešić, S. Richter, D. Gier, D. Bose, J. P. Dumm, T. Palczewski, C. Wichary, B. Eberhardt, H. S. Matis, K. Abraham, Francis Halzen, P. Zarzhitsky, O. Fadiran, R. Morse, H. Dembinski, Dariusz Gora, Physics, Elementary Particle Physics, Faculty of Sciences and Bioengineering Sciences, and Vriendenkring VUB

Subjects
Prompt leptons, lepton, Atmospheric muons, Cosmic rays, Astronomy and Astrophysics, Physics::Instrumentation and Detectors, Hadron, primary [cosmic radiation], PROTON, 01 natural sciences, IceCube, surface [detector], atmosphere [muon], NEUTRINO TELESCOPE, production [muon], Physics, High Energy Astrophysical Phenomena (astro-ph.HE), ELEMENTAL GROUPS, Detector, model [interaction], Astrophysics::Instrumentation and Methods for Astrophysics, COSMIC-RAY MUONS, ENERGY-SPECTRUM, vector meson, statistics, INTRINSIC CHARM, ddc:540, Physique des particules élémentaires, high [energy], Astrophysics - High Energy Astrophysical Phenomena, atmosphere [showers], Atmosperic muons, exceptional, air, flux [muon], Astrophysics::High Energy Astrophysical Phenomena, spectrum [multiplicity], energy spectrum, FOS: Physical sciences, Cosmic ray, atmosphere [cosmic radiation], Nuclear physics, cosmic rays, 0103 physical sciences, ARRIVAL DIRECTIONS, Vector meson, 010306 general physics, Zenith, ANISOTROPY, Muon, 010308 nuclear & particles physics, Spectral component, tracks, MODEL, Physics and Astronomy, 13. Climate action, TEV, spectral, High Energy Physics::Experiment, hadron, Lepton
Abstract

Muons produced in atmospheric cosmic ray showers account for the by far dominant part of the event yield in large-volume underground particle detectors. The IceCube detector, with an instrumented volume of about a cubic kilometer, has the potential to conduct unique investigations on atmospheric muons by exploiting the large collection area and the possibility to track particles over a long distance. Through detailed reconstruction of energy deposition along the tracks, the characteristics of muon bundles can be quantified, and individual particles of exceptionally high energy identified. The data can then be used to constrain the cosmic ray primary flux and the contribution to atmospheric lepton fluxes from prompt decays of short-lived hadrons. In this paper, techniques for the extraction of physical measurements from atmospheric muon events are described and first results are presented. The multiplicity spectrum of TeV muons in cosmic ray air showers for primaries in the energy range from the knee to the ankle is derived and found to be consistent with recent results from surface detectors. The single muon energy spectrum is determined up to PeV energies and shows a clear indication for the emergence of a distinct spectral component from prompt decays of short-lived hadrons. The magnitude of the prompt flux, which should include a substantial contribution from light vector meson di-muon decays, is consistent with current theoretical predictions. The variety of measurements and high event statistics can also be exploited for the evaluation of systematic effects. In the course of this study, internal inconsistencies in the zenith angle distribution of events were found which indicate the presence of an unexplained effect outside the currently applied range of detector systematics. The underlying cause could be related to the hadronic interaction models used to describe muon production in air showers., 0, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2016

29. Neutrino oscillation studies with IceCube-DeepCore

Author

P. O. Hulth, Björn Eichmann, H. Wissing, G. H. Collin, Daniel Bindig, Ramesh Koirala, T. C. Arlen, R. Gaior, Dennis Soldin, M. Relich, M. Song, Mike Richman, H. Taavola, H. S. Matis, N. Kurahashi, B. J. Whelan, J. Casey, D. V. Pankova, B. Riedel, Julian Kemp, K. Abraham, C. Walck, E. Blaufuss, A. Obertacke Pollmann, D. J. Boersma, J. C. Davis, L. Classen, J. L. Kelley, Markus Ahlers, T. Anderson, S. Hickford, M. Jurkovic, Francis Halzen, I. Ansseau, Thorsten Glusenkamp, George Japaridze, L. Schulte, M. Wallraff, M. Voge, M. Zoll, N. Buzinsky, M. Lesiak-Bzdak, A. Christov, G. Merino, K. Hoshina, Glenn Spiczak, W. Huelsnitz, N. Wandkowsky, K. Rawlins, M. Kauer, Samvel Ter-Antonyan, S. Westerhoff, L. Brayeur, E. Hansen, M. E. Huber, Donglian Xu, P. B. Price, Sander Vanheule, I. Taboada, K. Clark, A. Haj Ismail, L. Gerhardt, James Madsen, R. Nahnhauer, T. Menne, Lu Lu, Seongjin In, K. Helbing, A. Omairat, D. F. Cowen, U. Naumann, C. Kopper, M. Schimp, Kirill Filimonov, M. Kroll, D. Z. Besson, Todor Stanev, Dawn Williams, C. Wendt, Elisa Resconi, Azadeh Keivani, T. O. B. Schmidt, M. N. Tobin, J. Felde, P. Berghaus, Surujhdeo Seunarine, C. Pérez de los Heros, G. de Wasseige, S. Schoenen, Carl Pfendner, L. Wills, Teresa Montaruli, R. Hoffmann, K. D. de Vries, M. J. Larson, E. Unger, T. R. Wood, Juanan Aguilar, Darren Grant, J. P. Yanez, Dariusz Gora, E. del Pino Rosendo, J. Kunnen, S. Böser, Subir Sarkar, D. Heereman, L. Wille, M. Tselengidou, K. Meagher, Kendall Mahn, Thomas K. Gaisser, G. B. Yodh, G. W. Sullivan, James E. Braun, Kurt Woschnagg, Damian Pieloth, Delia Tosi, L. Schumacher, Hans Niederhausen, J. C. Gallagher, Sarah Nowicki, M. Casier, Paul Evenson, A. Bernhard, A. Ishihara, Ali Kheirandish, M. Day, D. R. Nygren, F. Bos, Javier Gonzalez, Joshua Pepper, Allan Hallgren, J. Feintzeig, R. Maunu, T. Stezelberger, Marek Kowalski, J. P. A. M. de André, Giorgio Maggi, Sandro Kopper, G. Tešić, T. Kuwabara, Dmitry Chirkin, T. Fuchs, C. De Clercq, L. Köpke, V. di Lorenzo, L. Mohrmann, R. Hellauer, R. C. Bay, E. Middell, K. Jero, Elisa Bernardini, Karim Ghorbani, Tim Ruhe, Matthias Wolf, Alexander Kappes, Thomas Ehrhardt, M. Leuermann, K. Schatto, G. Krückl, Christian Spiering, J. Auffenberg, Juan Carlos Diaz-Velez, Markus Ackermann, M. Archinger, G. Kohnen, Spencer Klein, Jenni Adams, S. W. Barwick, N. L. Strotjohann, E. Jacobi, J. Lünemann, M. G. Aartsen, M. Quinnan, R. Ström, J. J. Beatty, Kara Hoffman, M. Dunkman, Hermann Kolanoski, J. Becker Tjus, Carlos Arguelles, K. Wiebe, N. van Eijndhoven, T. Karg, Ch. Weaver, Justin Vandenbroucke, A. H. Cruz Silva, D. Hebecker, Sally Robertson, J. Posselt, R. Morse, X. Bai, G. Neer, Killian Holzapfel, G. Golup, Z. Griffith, B. J. P. Jones, Andrea Turcati, Hershal Pandya, Carsten Rott, Wolfgang Rhode, J. Blumenthal, Frank McNally, J. Leuner, A. Meli, A. Stößl, B. Hansmann, Thomas Meures, J. Veenkamp, Sofia Vallecorsa, Alexander Sandrock, K. Mase, J. van Santen, M. Bissok, R. Konietz, E. Beiser, G. Kroll, M. Glagla, Reina H. Maruyama, R. G. Stokstad, C. Haack, M. Mandelartz, Olga Botner, Joshua Hignight, Gary Binder, Axel Groß, A. Steuer, Minjin Jeong, R. Reimann, H. G. Sander, A. Terliuk, H. Dembinski, Xianwu Xu, M. Stamatikos, J. L. Lanfranchi, J. Sandroos, D. Altmann, V. Baum, C.-C. Fösig, A. Goldschmidt, L. Sabbatini, S. Tilav, K.-H. Becker, D. Gier, D. Bose, J. P. Dumm, T. Palczewski, Yiqian Xu, S. Yoshida, S. Euler, E. Pinat, B. Eberhardt, Simona Toscano, D. J. Koskinen, S. Flis, A. Stasik, Kael Hanson, Janet Conrad, Larissa Paul, E. Cheung, M. Usner, M. Rongen, M. S. Sutherland, Gerald Przybylski, Dirk Ryckbosch, M. Stahlberg, S. Richter, Paolo Desiati, M. Börner, Klas Hultqvist, J. Kiryluk, Albrecht Karle, K. Krings, S. Schöneberg, A. Schönwald, L. Rädel, J. Tatar, S. De Ridder, M. Labare, Maryon Ahrens, M. Rameez, M. Medici, S. Coenders, A. Wallace, M. Vehring, C. Ha, A. Olivas, F. Huang, A. Homeier, Christopher Wiebusch, C. Finley, J. Daughhetee, H.-P. Bretz, Christian Bohm, Aongus O'Murchadha, Christoph Raab, D. Berley, G. C. Hill, L. Gladstone, D. Seckel, S. Fahey, S. Miarecki, A. R. Fazely, Tyce DeYoung, P. A. Toale, Matthias Vraeghe, Physics, Elementary Particle Physics, Faculty of Sciences and Bioengineering Sciences, Massachusetts Institute of Technology. Department of Physics, Jones, Benjamin J. P., Christov, Asen, Montaruli, Teresa, Rameez, Mohamed, and Vallecorsa, Sofia

Subjects
Physics::Instrumentation and Detectors, Solar neutrino, pole, interaction [neutrino nucleon], PINGU, 01 natural sciences, 7. Clean energy, neutrino nucleon: interaction, IceCube, energy: threshold, Astronomi, astrofysik och kosmologi, neutrino: atmosphere, Astronomy, Astrophysics and Cosmology, detector [neutrino], Physics, neutrino: energy spectrum, oscillation [neutrino], Astrophysics::Instrumentation and Methods for Astrophysics, atmosphere [neutrino], threshold [energy], mass difference [neutrino], Cosmic neutrino background, neutrino: detector, Neutrino detector, Physique des particules élémentaires, Measurements of neutrino speed, Neutrino, performance, Nuclear and High Energy Physics, Particle physics, Astrophysics::High Energy Astrophysical Phenomena, neutrino: mass difference, ddc:500.2, neutrino: energy, SOUTH-POLE, 0103 physical sciences, ddc:530, 010306 general physics, Neutrino oscillation, 010308 nuclear & particles physics, ICE, energy spectrum [neutrino], Solar neutrino problem, neutrino: mixing angle, Physics and Astronomy, energy [neutrino], High Energy Physics::Experiment, neutrino: oscillation, Neutrino astronomy, MATTER, SYSTEM, mixing angle [neutrino], experimental results
Abstract

IceCube, a gigaton-scale neutrino detector located at the South Pole, was primarily designed to search for astrophysical neutrinos with energies of PeV and higher. This goal has been achieved with the detection of the highest energy neutrinos to date. At the other end of the energy spectrum, the DeepCore extension lowers the energy threshold of the detector to approximately 10 GeV and opens the door for oscillation studies using atmospheric neutrinos. An analysis of the disappearance of these neutrinos has been completed, with the results produced being complementary with dedicated oscillation experiments. Following a review of the detector principle and performance, the method used to make these calculations, as well as the results, is detailed. Finally, the future prospects of IceCube-DeepCore and the next generation of neutrino experiments at the South Pole (IceCube-Gen2, specifically the PINGU sub-detector) are briefly discussed., National Science Foundation (U.S.). Office of Polar Programs, National Science Foundation (U.S.). Physics Division, University of Wisconsin. Alumni Research Foundation, United States. Dept. of Energy

Published
2016

30. Constraints on ultra-high-energy cosmic ray sources from a search for neutrinos above 10 PeV with IceCube

Author

Julian Kemp, T. Anderson, Dirk Lennarz, Darren Grant, Thorsten Glusenkamp, P. B. Price, T. O. B. Schmidt, T. R. Wood, Kurt Woschnagg, Paul Evenson, Gabriel Collin, Dmitry Chirkin, Alexander Kappes, M. J. Larson, M. Lesiak-Bzdak, Killian Holzapfel, M. Kroll, C. Kopper, Sarah Nowicki, N. Kurahashi, B. J. Whelan, Thomas Meures, Frank McNally, A. Obertacke Pollmann, Tim Ruhe, C. Wendt, N. van Eijndhoven, K. D. de Vries, B. J. P. Jones, J. P. A. M. de André, A. Franckowiak, Marjon Moulai, E. Woolsey, M. Relich, A. Wallace, Da Xu, Kirill Filimonov, M. Vehring, R. Konietz, J. L. Kelley, Markus Ahlers, R. Ström, X. Bai, G. Neer, Christian Bohm, Aongus O'Murchadha, K. Helbing, L. Wille, J. C. Gallagher, S. E. Sanchez Herrera, G. de Wasseige, Karim Ghorbani, Spencer Axani, Christoph Raab, Joshua Pepper, K. Hoshina, F. Bos, C. Walck, Hans Niederhausen, A. Bernhard, U. Katz, Joshua Hignight, Janet Conrad, D. Berley, A. R. Fazely, Glenn Spiczak, G. C. Hill, Albrecht Karle, M. Glagla, R. Hoffmann, Allan Hallgren, Elisa Bernardini, K.-H. Becker, M. Jurkovic, D. F. Cowen, M. Tselengidou, M. Day, Yiqian Xu, Sandro Kopper, R. Cross, U. Naumann, P. Schlunder, Hrvoje Dujmovic, D. V. Pankova, L. Wills, Lew Classen, J. Kunnen, Alexander Burgman, Thomas K. Gaisser, G. B. Yodh, K. Jero, Samvel Ter-Antonyan, L. Schumacher, E. Cheung, Carlos Arguelles, S. Böser, Damian Pieloth, Ali Kheirandish, D. Hebecker, A. Christov, B. Riedel, E. Jacobi, M. Usner, E. Pinat, Simona Toscano, E. Unger, G. Krückl, T. Kintscher, L. Gladstone, C. Krüger, D. Seckel, S. Fahey, S. Miarecki, T. Menne, B. Relethford, Tyce DeYoung, J. Feintzeig, Matthias Wolf, M. Casier, Konstancja Satalecka, D. Z. Besson, Minjin Jeong, Andrea Turcati, M. Rongen, M. S. Sutherland, M. Kauer, R. C. Bay, V. di Lorenzo, Dirk Ryckbosch, A. Goldschmidt, S. Kunwar, L. Sabbatini, T. Karg, Ch. Weaver, Thomas Ehrhardt, George Japaridze, T. Fuchs, L. Köpke, Segev BenZvi, K. Clark, Spencer Klein, Stijn Vanheule, Kara Hoffman, Philipp Eller, M. Schimp, J. Felde, A. Steuer, A. Olivas, S. Hickford, F. Huang, M. Song, T. L. Carver, Mike Richman, E. Hansen, M. E. Huber, L. Gerhardt, P. A. Toale, J. van Santen, Stijn Blot, Christopher Wiebusch, M. Mandelartz, Gary Binder, Azadeh Keivani, Frederik Hermann Lauber, M. Zoll, J. P. Yanez, S. Westerhoff, Javier Gonzalez, Giorgio Maggi, Christian Spiering, C. De Clercq, David A. Williams, Justin Vandenbroucke, Markus Ackermann, S. W. Barwick, W. Giang, J. L. Lanfranchi, J. Becker Tjus, Carsten Rott, M. Bissok, Xianwu Xu, J. Sandroos, D. Altmann, P. Berghaus, E. del Pino Rosendo, Subir Sarkar, D. J. Koskinen, R. Maunu, D. Bose, J. P. Dumm, T. Palczewski, T. Stezelberger, B. Eberhardt, Sarah Mancina, M. Stahlberg, Juan Carlos Diaz-Velez, M. Archinger, J. J. Beatty, D. Rysewyk, S. Yoshida, T. Hansmann, S. Euler, K. Meagher, Alexander Sandrock, Gisela Anton, L. Mohrmann, Hershal Pandya, Wolfgang Rhode, A. Meli, D. R. Nygren, Marek Kowalski, S. Wickmann, J. Auffenberg, K. Krings, Ramesh Koirala, Dennis Soldin, H. Taavola, C. Finley, M. Wallraff, M. Voge, M. Leuermann, G. Kohnen, Seongjin In, Elisa Resconi, J. Lünemann, Kael Hanson, T. Kuwabara, J. Veenkamp, K. Rawlins, S. Tilav, A. Stasik, N. L. Strotjohann, M. Börner, Klas Hultqvist, J. Kiryluk, K. Andeen, G. W. Sullivan, Matthias Vraeghe, James E. Braun, James Madsen, Jenni Adams, K. Abraham, K. Mase, S. Schoenen, Hermann Kolanoski, Lu Lu, Björn Eichmann, H.-P. Bretz, Francis Halzen, A. Stößl, Reina H. Maruyama, J. Leuner, D. Heereman, Gerald Przybylski, E. Blaufuss, R. G. Stokstad, B. Hansmann, G. Golup, J. Tatar, Delia Tosi, C.-C. Fösig, I. Ansseau, A. Terliuk, Maximilian Meier, R. Hellauer, M. N. Tobin, Z. Griffith, H. Dembinski, M. Quinnan, G. Merino, G. Tešić, Ö. Penek, S. Schöneberg, Min Suk Kim, Paolo Desiati, N. Wandkowsky, E. Friedman, M. Dunkman, Daniel Bindig, Teresa Montaruli, C. Haack, M. J. Weiss, L. Brayeur, R. Nahnhauer, L. Rädel, Sally Robertson, M. G. Aartsen, Kendall Mahn, Surujhdeo Seunarine, I. Taboada, R. Reimann, T. Kittler, S. Flis, Juanan Aguilar, C. Pérez de los Heros, A. Ishihara, T. Stanev, Olga Botner, A. Haj Ismail, K. Wiebe, V. Baum, S. De Ridder, M. Labare, M. van Rossem, Maryon Ahrens, Frederik Tenholt, M. Rameez, M. Medici, S. Coenders, Vriendenkring VUB, Physics, and Elementary Particle Physics

Subjects
FLUX, SELECTION, FERMI-LAT, Active galactic nucleus, Cosmology and Nongalactic Astrophysics (astro-ph.CO), Astrophysics::High Energy Astrophysical Phenomena, General Physics and Astronomy, FOS: Physical sciences, Cosmic ray, Astrophysics, Parameter space, 7. Clean energy, 01 natural sciences, COSMOGENIC NEUTRINOS, TRACK RECONSTRUCTION, BURSTS, SPECTRUM, MODEL, TELESCOPES, EMISSION, Pulsar, 0103 physical sciences, ddc:550, Ultrahigh energy, 010303 astronomy & astrophysics, Physics, High Energy Astrophysical Phenomena (astro-ph.HE), 010308 nuclear & particles physics, Star formation, Astrophysics::Instrumentation and Methods for Astrophysics, Astronomy, Physics and Astronomy, 13. Climate action, High Energy Physics::Experiment, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, Energy (signal processing), Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

We report constraints on the sources of ultra-high-energy cosmic ray (UHECR) above $10^{9}$ GeV, based on an analysis of seven years of IceCube data. This analysis efficiently selects very high energy neutrino-induced events which have deposited energies from $\sim 10^6$ GeV to above $10^{11}$ GeV. Two neutrino-induced events with an estimated deposited energy of $(2.6 \pm 0.3) \times 10^6$ GeV, the highest neutrino energies observed so far, and $(7.7 \pm 2.0) \times 10^5$ GeV were detected. The atmospheric background-only hypothesis of detecting these events is rejected at 3.6$\sigma$. The hypothesis that the observed events are of cosmogenic origin is also rejected at $>$99% CL because of the limited deposited energy and the non-observation of events at higher energy, while their observation is consistent with an astrophysical origin. Our limits on cosmogenic neutrino fluxes disfavor the UHECR sources having cosmological evolution stronger than the star formation rate, e.g., active galactic nuclei and $\gamma$-ray bursts, assuming proton-dominated UHECRs. Constraints on UHECR sources including mixed and heavy UHECR compositions are obtained for models of neutrino production within UHECR sources. Our limit disfavors a significant part of parameter space for active galactic nuclei and new-born pulsar models., Comment: The erratum is bundled with the original published version of the letter together with supplemental materials

Published
2016
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31. Infusionsbedingtes Nieren- und Leberversagen bei undiagnostizierter hereditärer Fructose-Intoleranz*

Author

M Holm-Hadulla, L Wille, R Gitzelmann, B Steinmann, D E Müller-Wiefel, and K Schärer

Subjects
Kidney, medicine.medical_specialty, business.industry, Hereditary fructose intolerance, Liver failure, Fructose, General Medicine, Carbohydrate metabolism, medicine.disease, Recurrent abdominal pain, Gastroenterology, chemistry.chemical_compound, medicine.anatomical_structure, chemistry, Liver tissue, Internal medicine, medicine, business
Abstract

Appendectomy was performed in a 14 1/2-year-old boy with undiagnosed hereditary fructose intolerance because of chronic recurrent abdominal pain. During and after operation fructose containing solutions were infused. The patient received a total of 250 g fructose intravenously over 30 hours. Hours after onset of infusion he became soporous, hypoglycaemic and acidotic and was anuric after one day. Although the diagnosis was suspected by the end of the first postoperative day and fructose had been cancelled and haemodialysis been started, the boy died after a further 3 days with signs of acute kidney and liver failure. The diagnosis of hereditary fructose intolerance was biochemically established in post mortem liver tissue. This case recalls the fact that fructose, sorbitol or invert sugars should not be added to infusion solutions as they may be toxic for healthy persons and imply a lethal risk for patients with undiagnosed hereditary fructose intolerance, even well beyond the baby and infant period.

Published
2008

32. Search for dark matter annihilation in the Galactic Center with IceCube-79: IceCube Collaboration

Author

M. Labare, Maryon Ahrens, Thorsten Glusenkamp, M. Rameez, M. Medici, S. Coenders, H. S. Matis, Ramesh Koirala, Dennis Soldin, H. Taavola, C. De Clercq, K. Abraham, Francis Halzen, W. Huelsnitz, E. Blaufuss, D. J. Boersma, J. C. Davis, L. Classen, D. Tosi, O. Fadiran, Markus Ackermann, S. W. Barwick, A. Terliuk, M. Kauer, B. J. Whelan, Da Xu, Dawn Williams, C. Wendt, D. Gier, K. Krings, K. Helbing, A. Stasik, G. de Wasseige, R. Hoffmann, A. Homeier, J. P. Dumm, T. Palczewski, M. Relich, C. Wichary, B. Christy, J. C. Groh, R. Eagan, Gerald Przybylski, Larissa Paul, M. Tselengidou, Thomas K. Gaisser, G. B. Yodh, P. Gretskov, M. Vehring, J. Daughhetee, C. Ha, A. Koob, Benedikt Riedel, Marek Kowalski, P. B. Price, B. Eberhardt, George Japaridze, Carsten Rott, A. Karle, X. Bai, D. J. Koskinen, A. Christov, F. Scheriau, Anatoli Fedynitch, T. O. B. Schmidt, J. Becker Tjus, M. Kroll, K. Holzapfe, Sander Vanheule, M. Bissok, Naoko Kurahashi, T. R. Wood, Xianwu Xu, D. Altmann, Matthias Vraeghe, P. O. Hulth, Björn Eichmann, B. Kaminsky, Karim Ghorbani, Paul Evenson, S. Böser, J. Veenkamp, L. Schulte, G. Maggi, A. Omairat, M. Rongen, M. S. Sutherland, M. Day, H.-P. Bretz, B. Ruzybayev, M. E. Huber, Dmitry Chirkin, Thomas Meures, S. R. Klein, Christian Bohm, J. S. Gallagher, D. Bose, Alexander Kappes, Aongus O'Murchadha, H. Wissing, Alexander Sandrock, Carlos Arguelles, M. Leuermann, D. Z. Besson, A. Schönwald, Daniel Bindig, K. Meagher, Carl Pfendner, L. Gerhardt, A. Olivas, K. Schatto, G. Kohnen, K. Mase, D. Berley, G. C. Hill, Seongjin In, Elisa Resconi, Joakim Sandroos, Azadeh Keivani, Markus Ahlers, S. Vallecorsa, L. Gladstone, L. Rädel, M. Schmitz, D. Seckel, Stefan Richter, C. Haack, M. Wallraff, Darren Grant, M. W. E. Smith, M. Voge, S. Fahey, S. Miarecki, Tyce DeYoung, P. A. Toale, Nathan Whitehorn, K. Rawlins, M. Stamatikos, M. Quinnan, M. Dunkman, M. Casier, Karl J. Clark, R. Reimann, K. Jero, T. Stezelberger, S. M. Saba, L. Brayeur, Sarah Nowicki, J. Lünemann, A. Haj Ismail, R. C. Bay, J. Putz, K. Hoshina, D. Hellwig, M. J. Larson, F. Huang, Thomas Ehrhardt, James Madsen, Glenn Spiczak, Mike Richman, J. P. A. M. de André, J. Blumenthal, M. Stahlberg, I. Taboada, Dustin Hebecker, Rezo Shanidze, Samvel Ter-Antonyan, G. Golup, Juan Carlos Diaz-Velez, M. Archinger, E. Jacobi, A. R. Fazely, J. L. Kelley, M. Börner, Klas Hultqvist, J. P. Yanez, D. F. Cowen, M. Tobin, Dariusz Gora, C. Walck, C. Pérez de los Heros, J. J. Beatty, U. Naumann, S. Schoenen, Olga Botner, H. Dembinski, K. D. Hoffman, D. Heereman, Teresa Montaruli, E. Unger, E. Pinat, V. Baum, J. Posselt, A. Schukraft, Joanna Kiryluk, T. Karg, Ch. Weaver, L. Wille, G. W. Sullivan, James E. Braun, M. Jurkovic, Kendall Mahn, M. G. Aartsen, R. Hellauer, Hans Niederhausen, A. Bernhard, J. Casey, Fabian Bös, A. Stößl, D. R. Nygren, J. G. Gonzalez, J. Auffenberg, M. Zoll, A. Obertacke, T. C. Arlen, K. D. de Vries, Reina H. Maruyama, N. Buzinsky, S. Westerhoff, J. S. Miller, Sally Robertson, L. Mohrmann, Joshua Pepper, Allan Hallgren, R. Maunu, T. Kuwabara, T. Menne, Sandro Kopper, R. Gaior, Christian Spiering, S. Flis, J. Felde, E. Middell, Elisa Bernardini, K. Wiebe, C. Finley, Justin Vandenbroucke, S. Schöneberg, N. L. Strotjohann, Jenni Adams, J. L. Lanfranchi, Martin Wolf, Frank McNally, R. Konietz, Joshua Hignight, E. A. Strahler, J. van Santen, Hermann Kolanoski, Gary Binder, B. Hansmann, Axel Groß, Claudio Kopper, H. G. Sander, Subir Sarkar, G. Merino, N. Wandkowsky, R. Nahnhauer, Tim Ruhe, Richard G. Strom, Kael Hanson, Surujhdeo Seunarine, T. Fuchs, Juanan Aguilar, Paolo Desiati, Segev BenZvi, K. Filimonov, A. Ishihara, A. H. Cruz Silva, T. Stanev, J. Feintzeig, Hershal Pandya, Wolfgang Rhode, A. Meli, P. Berghaus, J. Kläs, S. Yoshida, S. Euler, P. Zarzhitsky, J. Kunnen, N. van Eijndhoven, Damian Pieloth, Ali Kheirandish, A. M. Brown, E. Beiser, L. Köpke, Julian Kemp, N. A. Stanisha, Michael Schimp, E. Middlemas, G. Kroll, M. Glagla, T. Anderson, M. Lesiak-Bzdak, P. Redl, K. Woschnagg, G. Tešić, C. H. Wiebusch, K.-H. Becker, Yiqian Xu, T. Fischer-Wasels, R. Morse, E. Cheung, M. Usner, Dirk Ryckbosch, J. Leuner, S. Hickford, R. G. Stokstad, A. Goldschmidt, L. Sabbatini, S. Tilav, and S. De Ridder

Subjects
Physics, Muon, Physics and Astronomy (miscellaneous), 010308 nuclear & particles physics, Milky Way, Astrophysics::High Energy Astrophysical Phenomena, Galactic Center, Dark matter, Astrophysics, Astrophysics::Cosmology and Extragalactic Astrophysics, 01 natural sciences, Dark matter halo, Neutrino detector, 13. Climate action, 0103 physical sciences, Physique des particules élémentaires, High Energy Physics::Experiment, Halo, Neutrino, 010303 astronomy & astrophysics, Engineering (miscellaneous), Astrophysics::Galaxy Astrophysics
Abstract

The Milky Way is expected to be embedded in a halo of dark matter particles, with the highest density in the central region, and decreasing density with the halo-centric radius. Dark matter might be indirectly detectable at Earth through a flux of stable particles generated in dark matter annihilations and peaked in the direction of the Galactic Center. We present a search for an excess flux of muon (anti-) neutrinos from dark matter annihilation in the Galactic Center using the cubic-kilometer-sized IceCube neutrino detector at the South Pole. There, the Galactic Center is always seen above the horizon. Thus, new and dedicated veto techniques against atmospheric muons are required to make the southern hemisphere accessible for IceCube. We used 319.7 live-days of data from IceCube operating in its 79-string configuration during 2010 and 2011. No neutrino excess was found and the final result is compatible with the background. We present upper limits on the self-annihilation cross-section, (Formula presented.), for WIMP masses ranging from 30 GeV up to 10 TeV, assuming cuspy (NFW) and flat-cored (Burkert) dark matter halo profiles, reaching down to ≃4·10-24 cm3 s-1, and ≃2.6·10-23 cm3 s-1 for the νν¯ channel, respectively., 0, SCOPUS: ar.j, info:eu-repo/semantics/published

Published
2015

33. Measurement of the AtmosphericνeSpectrum with IceCube

Author

Jenni Adams, Thorsten Glusenkamp, W. Huelsnitz, J. Pütz, J. Leuner, K. Helbing, Christian Spiering, R. G. Stokstad, Sander Vanheule, Justin Vandenbroucke, M. Richman, L. Classen, D. Z. Besson, K. Clark, M. Stamatikos, M. Leuermann, K. Schatto, G. Kohnen, M. W. E. Smith, Javier Gonzalez, J. L. Lanfranchi, P. Berghaus, Dariusz Gora, Sofia Vallecorsa, J. Kläs, A. Stasik, J. Feintzeig, Gerald Przybylski, M. Schimp, L. Brayeur, Giorgio Maggi, C. De Clercq, J. Kunnen, George Japaridze, K. Rawlins, R. Hellauer, E. A. Strahler, S. Böser, A. Homeier, M. Rongen, M. Day, M. S. Sutherland, I. Taboada, J. Felde, M. Quinnan, Damian Pieloth, Ali Kheirandish, M. Dunkman, Joakim Sandroos, Azadeh Keivani, H. G. Sander, J. Blumenthal, David A. Williams, K. Meagher, Y. Sestayo, Olga Botner, V. Baum, Christopher Wiebusch, James Madsen, Joshua Pepper, Nathan Whitehorn, Hermann Kolanoski, A. M. Brown, A. Goldschmidt, Sally Robertson, S. Richter, Markus Ackermann, S. W. Barwick, J. P. Yanez, E. Middell, Elisa Bernardini, G. Tešić, J. Daughhetee, Seongjin In, Carsten Rott, B. Hansmann, C. Walck, T. Fuchs, Elisa Resconi, M. Bissok, Anatoli Fedynitch, J. L. Kelley, Markus Ahlers, M. Kroll, G. W. Sullivan, James E. Braun, M. N. Tobin, O. Schulz, R. Maunu, H. S. Matis, J. C. Groh, S. Flis, M. Jurkovic, L. Köpke, J. Becker Tjus, Xianwu Xu, D. Altmann, Dennis Soldin, C. Kopper, T. Kuwabara, Teresa Montaruli, K. D. de Vries, M. Kauer, Francis Halzen, Samvel Ter-Antonyan, H. Taavola, M. Zoll, Segev BenZvi, N. Buzinsky, S. Westerhoff, Kendall Mahn, P. Zarzhitsky, M. Wallraff, M. Voge, G. Golup, L. Schulte, J. A. Goodman, R. Morse, Spencer Klein, O. Fadiran, T. Menne, A. Terliuk, L. Sabbatini, B. Kaminsky, J. C. Gallagher, D. Hellwig, Tim Ruhe, C. Pérez de los Heros, H. Dembinski, M. Stahlberg, A. Haj Ismail, N. L. Strotjohann, P. Gretskov, G. Merino, N. Wandkowsky, A. Omairat, D. J. Koskinen, Kara Hoffman, F. Bos, D. Gier, M. Börner, Klas Hultqvist, J. Kiryluk, Allan Hallgren, D. Bose, A. H. Cruz Silva, E. Blaufuss, D. J. Boersma, J. C. Davis, R. Nahnhauer, R. Ström, Surujhdeo Seunarine, J. Miller, J. P. Dumm, J. J. Beatty, Karim Ghorbani, Sandro Kopper, T. Palczewski, E. Jacobi, C. Wichary, Darren Grant, D. Hebecker, A. Olivas, Juanan Aguilar, S. Tilav, H.-P. Bretz, J. Casey, X. Bai, L. Wille, B. Eberhardt, Wolfgang Rhode, T. Karg, Ch. Weaver, A. Meli, J. Posselt, R. Gaior, M. Schmitz, K. Jero, N. Kurahashi, B. J. Whelan, S. Schöneberg, F. Huang, Carlos Arguelles, Todor Stanev, Sarah Nowicki, Matthias Wolf, Matthias Vraeghe, Hans Niederhausen, A. Christov, A. Bernhard, Julian Kemp, P. O. Hulth, Thomas Ehrhardt, B. Ruzybayev, B. Christy, L. Rädel, K. Wiebe, Thomas Meures, A. Ishihara, N. A. Stanisha, J. van Santen, A. Stößl, Björn Eichmann, T. Anderson, M. Vehring, D. F. Cowen, K.-H. Becker, Yiqian Xu, T. Fischer-Wasels, C. Wendt, C. Ha, Reina H. Maruyama, Alexander Sandrock, J. P. A. M. de André, P. B. Price, M. Lesiak-Bzdak, P. Redl, H. Wissing, Gary Binder, Axel Groß, K. Mase, K. Hoshina, A. Schukraft, C. Finley, T. O. B. Schmidt, T. C. Arlen, T. Stezelberger, S. M. Saba, Glenn Spiczak, Daniel Bindig, E. Cheung, E. Pinat, M. Usner, T. R. Wood, Dirk Ryckbosch, C. Haack, Kurt Woschnagg, M. Casier, U. Naumann, M. Relich, E. Unger, Christian Bohm, Donglian Xu, Paul Evenson, Kirill Filimonov, G. de Wasseige, R. Reimann, R. Hoffmann, Dmitry Chirkin, Aongus O'Murchadha, J. Lünemann, L. Mohrmann, Alexander Kappes, Subir Sarkar, R. C. Bay, B. Riedel, D. Berley, G. C. Hill, Rezo Shanidze, Juan Carlos Diaz-Velez, M. Archinger, L. Gladstone, D. Seckel, S. Fahey, S. Miarecki, D. R. Nygren, Marek Kowalski, A. R. Fazely, Tyce DeYoung, P. A. Toale, J. Auffenberg, A. Obertacke, R. Eagan, M. Tselengidou, Thomas K. Gaisser, G. B. Yodh, Frank McNally, R. Konietz, K. Krings, Joshua Hignight, S. De Ridder, M. Labare, Maryon Ahrens, M. Rameez, M. Medici, S. Coenders, Larissa Paul, F. Scheriau, A. Koob, Albrecht Karle, M. E. Huber, L. Gerhardt, A. Schönwald, S. Hickford, M. J. Larson, S. Schoenen, D. Heereman, Delia Tosi, M. G. Aartsen, S. Euler, C. Pfendner, Kael Hanson, Paolo Desiati, S. Yoshida, N. van Eijndhoven, E. Beiser, E. Middlemas, G. Kroll, M. Glagla, Physics, and Elementary Particle Physics

Subjects
AMANDA, Nuclear and High Energy Physics, Particle physics, Astrophysics::High Energy Astrophysical Phenomena, Hadron, CASCADES, 01 natural sciences, 7. Clean energy, Power law, IceCube, Nuclear physics, Flux (metallurgy), DESIGN, Likelihood analysis, DIGITIZATION, 0103 physical sciences, NEUTRINO FLUX, 010306 general physics, DETECTOR, Physics, 010308 nuclear & particles physics, ICE, High Energy Physics::Phenomenology, Spectrum (functional analysis), Detector, PERFORMANCE, ENERGY-SPECTRUM, Event selection, Physics and Astronomy, High Energy Physics::Experiment, Neutrino, Astrophysics - High Energy Astrophysical Phenomena, physics, SYSTEM
Abstract

We present a measurement of the atmospheric $\nu_e$ spectrum at energies between 0.1 TeV and 100 TeV using data from the first year of the complete IceCube detector. Atmospheric $\nu_e$ originate mainly from the decays of kaons produced in cosmic-ray air showers. This analysis selects 1078 fully contained events in 332 days of livetime, then identifies those consistent with particle showers. A likelihood analysis with improved event selection extends our previous measurement of the conventional $\nu_e$ fluxes to higher energies. The data constrain the conventional $\nu_e$ flux to be $1.3^{+0.4}_{-0.3}$ times a baseline prediction from a Honda's calculation, including the knee of the cosmic-ray spectrum. A fit to the kaon contribution ($\xi$) to the neutrino flux finds a kaon component that is $\xi =1.3^{+0.5}_{-0.4}$ times the baseline value. The fitted/measured prompt neutrino flux from charmed hadron decays strongly depends on the assumed astrophysical flux and shape. If the astrophysical component follows a power law, the result for the prompt flux is $0.0^{+3.0}_{-0.0}$ times a calculated flux based on the work by Enberg, Reno and Sarcevic., Comment: PRD accepted version

Published
2015

34. Prostaglandins and the Ductus Arteriosus

Author

H. W. Seyberth, L. Wille, and H. E. Ulmer

Subjects
medicine.medical_specialty, medicine.anatomical_structure, business.industry, Ductus arteriosus, Internal medicine, Cardiology, Medicine, business
Published
2015

35. Maple Syrup Urine Disease: Emergency Treatment of the Neonate

Author

Peter Lutz, G Hammersen, H. Schmidt, Horst Bickel, and L. Wille

Subjects
medicine.medical_specialty, Pediatrics, business.industry, Maple syrup urine disease, medicine.medical_treatment, Exchange transfusion, Emergency treatment, medicine.disease, Infant newborn, Endocrinology, Parenteral nutrition, Internal medicine, medicine, business, Whole blood
Published
2015

40. Some Conceptual Issues and Empirical Trends in the Study of Successful Mediation in International Relations

Author

Donnette L. Wille, J. Theodore Anagnoson, and Jacob Bercovitch

Subjects
Party-directed mediation, International relations, Sociology and Political Science, education, Identity (social science), Poison control, Dispute mechanism, Conciliation, Affect (psychology), Political Science and International Relations, Mediation, Psychology, Safety Research, Social psychology
Abstract

Despite its ubiquity and importance as a means of managing international conflict, mediation has only recently begun to be studied in a systematic manner. This article utilizes an original dataset of international disputes and mediation efforts occurring in the 1945-89 period to assess the character of international mediation and to examine the contextual and process variables which affect mediation outcomes. These variables are classed under four categories: (1) the nature of the disputing parties, (2) the nature of the dispute itself, (3) the identity and characteristics of the mediator, and (4) the strategies and tactics which the mediator employs. In this study, a preliminary analysis is undertaken to determine the nature and degree to which the variables in each of these categories affect mediation outcomes. The results indicate that dispute intensity, mediator strategies and dispute issues exert the greatest influence on the effectiveness of international mediation. A complex of other factors, including the timing of entry into mediation, the power disparity between the disputants and the nature of the disputants' former relations also demonstrate an effect, though somewhat weaker, on mediation outcomes. The article presents conclusions on the effectiveness of international mediation and points the way for more much-needed empirical work in this area.

Published
1991

41. Can microsatellite data allow identification of oleaster Plio-Pleistocene refuge zones in the Mediterranean Basin?

Author

Pascal-Antoine Christin, Philippe Henry, Guillaume Besnard, Elodie Chapuis, L. Wille, Perturbations & Virulence in Populations & Communities (MIVEGEC-Perturbations & Virulence in Populations & Communities ), Perturbations, Evolution, Virulence (PEV), Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Maladies infectieuses et vecteurs : écologie, génétique, évolution et contrôle (MIVEGEC), and Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])-Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS)-Institut de Recherche pour le Développement (IRD [France-Sud])

Subjects
0106 biological sciences, 0303 health sciences, Ecology, [SDV]Life Sciences [q-bio], [SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE], Plio-Pleistocene, Biology, 01 natural sciences, Mediterranean Basin, 03 medical and health sciences, [SDE]Environmental Sciences, Microsatellite, Identification (biology), 14. Life underwater, Ecology, Evolution, Behavior and Systematics, ComputingMilieux_MISCELLANEOUS, 030304 developmental biology, 010606 plant biology & botany, [SDV.EE.IEO]Life Sciences [q-bio]/Ecology, environment/Symbiosis
Abstract

International audience

Published
2007

42. On the origin of the invasive olives (Olea europaea L., Oleaceae)

Author

L. Wille, Philippe Henry, D Cooke, Guillaume Besnard, and Elodie Chapuis

Subjects
education.field_of_study, Genetic diversity, biology, Oleaceae, Population, Population genetics, Subspecies, biology.organism_classification, Biological Evolution, Invasive species, Intergenic region, Genetics, Population, Olea, Botany, Genetics, Plastids, education, Oleaceae/genetics, Oleaceae/growth & development, Phylogeny, Plastids/genetics, Genetics (clinical)
Abstract

The olive tree (Olea europaea) has successfully invaded several regions in Australia and Pacific islands. Two olive subspecies (subspp. europaea and cuspidata) were first introduced in these areas during the nineteenth century. In the present study, we determine the origin of invasive olives and investigate the importance of historical effects on the genetic diversity of populations. Four invasive populations from Australia and Hawaii were characterized using eight nuclear DNA microsatellites, plastid DNA markers as well as ITS-1 sequences. Based on these data, their genetic similarity with native populations was investigated, and it was determined that East Australian and Hawaiian populations (subsp. cuspidata) have originated from southern Africa while South Australian populations (subsp. europaea) have mostly derived from western or central Mediterranean cultivars. Invasive populations of subsp. cuspidata showed significant loss of genetic diversity in comparison to a putative source population, and a recent bottleneck was evidenced in Hawaii. Conversely, invasive populations of subsp. europaea did not display significant loss of genetic diversity in comparison to a native Mediterranean population. Different histories of invasion were inferred for these two taxa with multiple cultivars introduced restoring gene diversity for europaea and a single successful founder event and sequential introductions to East Australia and then Hawaii for cuspidata. Furthermore, one hybrid (cuspidata × europaea) was identified in East Australia. The importance of hybridizations in the future evolution of the olive invasiveness remains to be investigated.

Published
2007

43. Complementary and alternative medicine and musculoskeletal pain in the first year of adjuvant aromatase inhibitor treatment in early breast cancer patients

Author

C.C. Hack, L. Häberle, S.Y. Brucker, W. Janni, B. Volz, C.R. Loehberg, A.D. Hartkopf, C.-B. Walter, G. Baake, A. Fridman, W. Malter, R. Wuerstlein, N. Harbeck, O. Hoffmann, S. Kuemmel, B. Martin, C. Thomssen, H. Graf, C. Wolf, M.P. Lux, C.M. Bayer, C. Rauh, K. Almstedt, P. Gass, F. Heindl, T. Brodkorb, L. Willer, C. Lindner, H.-C. Kolberg, P. Krabisch, M. Weigel, D. Steinfeld-Birg, A. Kohls, C. Brucker, V. Schulz, G. Fischer, V. Pelzer, B. Rack, M.W. Beckmann, T. Fehm, A. Rody, N. Maass, A. Hein, P.A. Fasching, and N. Nabieva

Subjects
Breast cancer, Endocrine therapy/treatment, Aromatase inhibitors, Letrozole, Integrative medicine, Complementary and alternative medicine, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
Abstract

Background: Patients with breast cancer (BC) show strong interest in complementary and alternative medicine (CAM), particularly for adverse effects of adjuvant endocrine treatment — e.g., with letrozole. Letrozole often induces myalgia/limb pain and arthralgia, with potential noncompliance and treatment termination. This analysis investigated whether CAM before aromatase inhibitor (AI) therapy is associated with pain development and the intensity of AI-induced musculoskeletal syndrome (AIMSS) during the first year of treatment. Patients and methods: The multicenter phase IV PreFace study evaluated letrozole therapy in postmenopausal, hormone receptor–positive patients with early BC. Patients were asked about CAM use before, 6 months after, and 12 months after treatment started. They recorded pain every month for 1 year in a diary including questions about pain and numeric pain rating scales. Data were analyzed for patients who provided pain information for all time points. Results: Of 1396 patients included, 901 (64.5%) had used CAM before AI treatment. Throughout the observation period, patients with CAM before AI treatment had higher pain values, for both myalgia/limb pain and arthralgia, than non-users. Pain increased significantly in both groups over time, with the largest increase during the first 6 months. No significant difference of pain increase was noted regarding CAM use. Conclusions: CAM use does not prevent or improve the development of AIMSS. Pain intensity was generally greater in the CAM group. Therefore, because of the risk of non-compliance and treatment discontinuation due to the development of higher pain levels, special attention must be paid to patient education and aftercare in these patients.

Published
2020
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44. Improving collaboration between ecosystem service communities and the IPBES science-policy platform

Author

C.-L. Washbourne, N. Dendoncker, S. Jacobs, A. Mascarenhas, F. De Longueville, A. P. E. van Oudenhoven, M. Schröter, L. Willemen, S. Campagne, S.K. Jones, M. Garcia-Llorente, I. Iniesta-Arandia, F. Baró, J. Fisher, J. Förster, C. Jericó-Daminelo, J. Lecina-Diaz, S. Lavorel, B. Lliso, C. Montealgre Talero, A. Morán-Ordóñez, J.V. Roces-Díaz, M.A. Schlaepfer, and J. Van Dijk

Subjects
harini nagendra, Human ecology. Anthropogeography, GF1-900, Environmental sciences, GE1-350
Abstract

The end of the first working program of the Intergovernmental Science-Policy Platform on Biodiversity and Ecosystem Services (IPBES) provided an opportunity to draw lessons from its work. This perspective paper captures insights from ecosystem services (ES) researchers and practitioners, largely drawing from the European context (referred to herein as ‘ES community’), on this key science–policy interface. We synthesize reflections from a workshop on how (i) IPBES can engage the ES community; (ii) the ES community can engage with IPBES; and (iii) individual scientists can contribute. We note that IPBES constitutes a great advancement towards multidisciplinarity and inclusivity in ES research and practice. Key reflections for IPBES are that funding and visibility at ES research events could be improved, the contribution and selection processes could be more transparent, and communication with experts improved. Key reflections for the ES community include a need to improve policy-relevance by integrating more social scientists, researchers from developing countries, early-career scientists and policy-makers. Key reflections directed towards individual scientists include contributing (pro)actively to science–policy interface initiatives such as IPBES and increasing transdisciplinary research. These reflections intend to contribute to the awareness of challenges and opportunities for institutions, groups and individuals working on ES.

Published
2020
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46. Sunscreens in Melanoma Protection - Pros and Cons

Author

K. F. Kölmel, Olaf Gefeller, and L. Wille

Subjects
medicine.medical_specialty, Skin cancer screening, business.industry, Melanoma, Cutaneous melanoma, Medicine, Skin cancer, business, medicine.disease, Dermatology
Abstract

The use of sunscreens is widely advocated as a protective measure against the development of melanoma of the skin. However, the discussion about this issue in the current epidemiological literature is controversial. The aim of this paper is to evaluate the association between the use of sunscreens and the development of malignant melanoma by a meta-analytical approach based on the quantitative results of all published studies.

Published
1997

47. [Fibrosing alveolitis in a 7-year-old girl with autoimmune hemolytic anemia and autoimmune hepatitis]

Author

K, Paul, L, Wille, D, Feist, and K, Kayser

Subjects
Pulmonary Atelectasis, Prednisolone, Pulmonary Fibrosis, Humans, Female, Anemia, Hemolytic, Autoimmune, Bronchography, Child, Autoimmune Diseases, Hepatitis
Abstract

A Coombs-positive haemolytic anaemia with proof of heat autoagglutinins and autoantibodies against cell nuclei was diagnosed in a girl, now 7 1/2 years of age, in the sixth month of her life as a sequel to jaundice. Shortly afterwards liver biopsy yielded a confirmed diagnosis of giant cell hepatitis. The signs of the disease receded under treatment with decortin and imurek. An attempt to discontinue the medication at 5 1/2 years of age resulted in a histologically confirmed recurrence of autoimmune hepatitis. When the patient was 5 years old, the x-ray revealed a mainly interstitial pneumonia; at 6 years of age, bronchiectases in the region of the left lower lobe were confirmed by bronchography. Resection of the lower lobe was performed after occurrence of atelectasis. Histopathological findings confirmed fibrotic alveolitis associated with giant cells. Based on the overall clinical course and the histological and immunological findings, autoimmune etiology of fibrotic alveolitis must be discussed. Progression of the disease could be avoided during the past 6 months by intensifying the immunosuppressive prednisolone therapy.

Published
1991

48. Alteration of the lung parenchyma associated with autoimmune hepatitis

Author

D. Feist, L. Wille, Hans-Joachim Gabius, K. Paul, Walter J. Hofmann, and K. Kayser

Subjects
Pathology, medicine.medical_specialty, Autoimmune hepatitis, Pathology and Forensic Medicine, Autoimmune Diseases, Parenchyma, medicine, Humans, Molecular Biology, Lung, Hepatitis, Chronic, Hepatitis, Autoimmune disease, Bronchiectasis, business.industry, Respiratory disease, Infant, Cell Biology, General Medicine, medicine.disease, medicine.anatomical_structure, Giant cell, Immunology, Female, business
Abstract

The clinical history, radiological and histomorphological alterations of the lung parenchyma associated with chronic active autoimmune hepatitis are described. A 6-month-old female infant developed chronic active autoimmune hepatitis associated with autoimmune haemolytic anaemia. She was treated with immunosuppressive drugs, including steroids, for more than 6 years and developed symptoms and radiological signs of interstitial pneumonitis 4 years after onset of the autoimmune hepatitis. Associated bronchiectasis was detected 1 year later. No abnormalities of lung defence mechanisms could be demonstrated. Resection of the sixth left segment and of the basal parts of the left lower lobe revealed honeycombing with changes in the lung parenchyma which included chronic interstitial pneumonitis with multinucleate giant cells, seen predominantly in the distal airways, marked diffuse interstitial mononuclear infiltrates and mild diffuse interstitial fibrosis as well as bronchiectasis and organizing pneumonia. Granulomatous lesions, angiitis and necrotic areas were absent. Immunohistochemistry for immunoglobulins was negative for IgA, IgG and IgM and positive for IgD in the multinucleate giant cells. A strong positive reaction to HLA-DR-specific monoclonal antibody was noted, whereas no specific sugar receptors (endogenous lectins) could be detected by use of biotinylated glyconeoproteins.

Published
1991

49. The Development of Practice Recommendations for Drug-Disease Interactions by Literature Review and Expert Opinion

Author

Justine M. Z. van Tongeren, S. Froukje Harkes-Idzinga, Heleen van der Sijs, Roya Atiqi, Bart J. F. van den Bemt, L. Willem Draijer, Deline Hiel, Adrian Kerremans, Bart Kremers, Marc de Leeuw, Marleen V. Olthoff, T. Kim-Loan Pham, Ricky Valentijn-Robertz, Kayan Tsoi, Iris Wichers, Maaike de Wit, and Sander D. Borgsteede

Subjects
drug-disease interactions, literature review, expert opinion, study protocol, practice recommendations, clinical decision support, Therapeutics. Pharmacology, RM1-950
Abstract

BackgroundDrug-disease interactions negatively affect the benefit/risk ratio of drugs for specific populations. In these conditions drugs should be avoided, adjusted, or accompanied by extra monitoring. The motivation for many drug-disease interactions in the Summary of Product Characteristics (SmPC) is sometimes insufficiently supported by (accessible) evidence. As a consequence the translation of SmPC to clinical practice may lead to non-specific recommendations. For the translation of this information to the real world, it is necessary to evaluate the available knowledge about drug-disease interactions, and to formulate specific recommendations for prescribers and pharmacists. The aim of this paper is to describe a standardized method how to develop practice recommendations for drug-disease interactions by literature review and expert opinion.MethodsThe development of recommendations for drug-disease interactions will follow a six-step plan involving a multidisciplinary expert panel (1). The scope of the drug-disease interaction will be specified by defining the disease and by describing relevant effects of this drug-disease interaction. Drugs possibly involved in this drug-disease interaction are selected by checking the official product information, literature, and expert opinion (2). Evidence will be collected from the official product information, guidelines, handbooks, and primary literature (3). Study characteristics and outcomes will be evaluated and presented in standardized reports, including preliminary conclusions on the clinical relevance and practice recommendations (4). The multidisciplinary expert panel will discuss the reports and will either adopt or adjust the conclusions (5). Practice recommendations will be integrated in clinical decision support systems and published (6). The results of the evaluated drug-disease interactions will remain up-to-date by screening new risk information, periodic literature review, and (re)assessments initiated by health care providers.Actionable RecommendationsThe practice recommendations will result in advices for specific DDSI. The content and considerations of these DDSIs will be published and implemented in all Clinical Decision Support Systems in the Netherlands.DiscussionThe recommendations result in professional guidance in the context of individual patient care. The professional will be supported in the decision making in concerning pharmacotherapy for the treatment of a medical problem, and the clinical risks of the proposed medication in combination with specific diseases.

Published
2020
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