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3 results on '"L. Wenyan"'

1. Omics approach and novel biostatistic tools identified RPL3L as potential genetic modifier of clinical severity in female carriers of Duchenne muscle dystrophy

Author

C. Scotton, Eugenio Mercuri, Chiara Passarelli, Anton Yuryev, Chiara Scapoli, Annarita Armaroli, Graziano Pesole, L. Wenyan, Enrico Bertini, Francesca Gualandi, Samuele Gherardi, Alessandra Ferlini, Marika Pane, Adele D'Amico, Elena Schwartz, Alberto Carrieri, Matteo Bovolenta, F. Mingyan, F. Di Raimo, and Marcella Neri

Subjects
Genetics, Neurology, Pediatrics, Perinatology and Child Health, Clinical severity, Neurology (clinical), Muscle dystrophy, Computational biology, Biology, Omics, Genetics (clinical), NO
Published
2015

2. Endovascular Aneurysm Treatment with the Numen Coil Embolization System: A Prospective Randomized Controlled Open-Label Multicenter Noninferiority Trial in China.

Author

Zhao R, Duan G, Yang P, Li T, Guan S, Yang H, Zhao Z, Zhu X, Liang G, Wu X, Leng B, Wang Y, Wu Y, Zuo Q, Zhang L, Li Z, Zhou Y, Zhao K, Dai D, Fang Y, Li Q, Huang Q, Hong B, Xu Y, Liu J, Kaixia Z, Gong C, Qingzhu A, Yongtao Z, Yingkun H, Weixing B, Zhang L, Xiaoyu K, Ning W, Min G, Bin X, Guangming D, Li L, Liangfu Z, Zhilong Z, Qiuji S, Kaitao C, Liheng W, Qiang L, Jianjun G, Kun Z, Yongfeng W, Zhiyu Z, Zhen C, Haowen X, Linyu W, Xinbin G, Chao L, Feng F, Zining L, Yuanyuan G, Hu C, Zhongjun Y, Wei F, Wenyan L, Jiang L, Jianping D, Zhihong L, Xu G, Xiaogang W, Yushu D, Chuangzhong L, Song L, Lu T, Yuan Y, Minghua S, Zaiqiang Z, Jing W, Guifeng S, Jiyong C, Zhen Z, Xiaobing Z, Yan C, Lingfeng L, Youqing D, Guohua M, Jianming Z, Xianliang L, Ziyun G, Shuxin S, Minhua Y, Yijin F, Xin X, Han P, Jian Y, and Wenting F

Subjects
Follow-Up Studies, Humans, Prospective Studies, Treatment Outcome, Aortic Aneurysm, Abdominal, Blood Vessel Prosthesis Implantation, Embolization, Therapeutic methods, Endovascular Procedures methods, Intracranial Aneurysm etiology, Intracranial Aneurysm surgery
Abstract

Objective: We investigated the safety and efficacy of the Numen coil compared with the Axium coil in the treatment of intracranial aneurysms., Methods: Because CATCH (Coil Application Trial in China) is a prospective randomized controlled open-label noninferiority trial conducted in 10 centers across China, patients who fulfilled the inclusion and exclusion criteria were randomized 1:1 to either a test group (Numen) or a control group (Axium). The primary outcome was based on successful aneurysm occlusion at 6 months follow-up, whereas secondary outcomes included technical success, the recanalization and retreatment rates, and the rate of serious adverse events (SAEs) at 6 months and 12 months follow-up., Results: Between August 2017 and December 2019, 350 patients presenting with 350 aneurysms were enrolled and randomized. Per-protocol analysis showed that the successful aneurysm occlusion rate at 6 months was 91.18% for the test group compared with 91.85% in the control group, with a difference of -0.68% (P = 0.8419), and the overall mortality during the 30-day follow-up period was 1.19% and 1.81% in the test and control group, respectively, showing no significant difference between the 2 groups (P = 0.6837), whereas the SAE incidence during the 12-month follow-up period was 12.50% and 17.47% in the test and control groups, respectively, which was not statistically significant (P = 0.2222)., Conclusions: This trial showed that the Numen coil was noninferior to the Axium coil in terms of intracranial aneurysm embolization and can be considered as a safe and effective coil for treating patients with intracranial aneurysm in clinical practice., (Copyright © 2021 Elsevier Inc. All rights reserved.)

Published
2022
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3. Application of clone library analysis and real-time PCR for comparison of microbial communities in a low-grade copper sulfide ore bioheap leachate.

Author

Bowei C, Xingyu L, Wenyan L, and Jiankang W

Subjects
Archaea isolation & purification, Bacteria isolation & purification, China, Cluster Analysis, Copper metabolism, DNA, Archaeal chemistry, DNA, Archaeal genetics, DNA, Bacterial chemistry, DNA, Bacterial genetics, DNA, Ribosomal chemistry, DNA, Ribosomal genetics, Genes, rRNA, Molecular Sequence Data, Phylogeny, Polymorphism, Restriction Fragment Length, RNA, Archaeal genetics, RNA, Bacterial genetics, RNA, Ribosomal, 16S genetics, Sequence Analysis, DNA, Sequence Homology, Nucleic Acid, Sulfides metabolism, Archaea classification, Archaea genetics, Bacteria classification, Bacteria genetics, Biodiversity, Polymerase Chain Reaction methods, Soil Microbiology
Abstract

The microbial communities of leachate from a bioleaching heap located in China were analyzed using the 16S rRNA gene clone library and real-time quantitative PCR. Both methods showed that Leptospirillum spp. were the dominant bacteria, and Ferroplasma acidiphilum were the only archaea detected in the leachate. Clone library results indicated that nine operational taxonomic units (OTUs) were obtained, which fell into four divisions, the Nitrospirae (74%), the gamma-Proteobacteria (14%), the Actinobacteria (6%) and the Euryarchaeota (6%). The results obtained by real-time PCR in some ways were the same as clone library analysis. Furthermore, Sulfobacillus spp., detected only by real-time PCR, suggests that real-time PCR was a reliable technology to study the microbial communities in bioleaching environments. It is a useful tool to assist clone library analysis, to further understand microbial consortia and to have comprehensive and exact microbiological information about bioleaching environments. Finally, the interactions among the microorganisms detected in the leachate were summarized according to the characteristics of these species.

Published
2009
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