40 results on '"L. Stradella"'
Search Results
2. Phytoestrogens for menopausal vasomotor symptoms: efficacy of soybean isoflavones supplements for alleviating menopausal symptoms is positively related to hot flushes frequency
- Author
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M. Passaro, Domenico Ambrosio, Mario Rotondi, Labriola D, Schettino Mt, R. Sgambato, C. Stradella, L. Stradella, Marco Torella, and G Mainini
- Subjects
chemistry.chemical_compound ,Reproductive Medicine ,chemistry ,Vasomotor ,business.industry ,Obstetrics and Gynecology ,Medicine ,Physiology ,Phytoestrogens ,Isoflavones ,business - Published
- 2017
3. Milk from cows fed a diet with a high forage:concentrate ratio improves inflammatory state, oxidative stress, and mitochondrial function in rats
- Author
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Raffaella Tudisco, Giovanni Messina, Monica Isabella Cutrignelli, Giovanna Trinchese, Nadia Musco, Serena Calabrò, Chiara De Filippo, Marcellino Monda, Vincenzo Monda, Marianna Crispino, Pietro Lombardi, Vincenzo Mastellone, Heleena B. Moni, Antonietta Messina, Gina Cavaliere, Micaela Grossi, Federico Infascelli, Valeria Maria Morittu, L Stradella, Maria Pina Mollica, Cavaliere, G, Trinchese, G, Musco, N, Infascelli, F, De Filippo, C, Mastellone, V, Morittu, Vm, Lombardi, P, Tudisco, R, Grossi, M, Monda, V, Cutrignelli, Mi, Messina, A, Calabrò, S, Moni, Hb, Stradella, L, Messina, G, Monda, M, Crispino, M, Mollica, Mp., Cavaliere, Gina, Trinchese, Giovanna, Musco, Nadia, Infascelli, Federico, De Filippo, Chiara, Mastellone, Vincenzo, Morittu, Valeria Maria, Lombardi, Pietro, Tudisco, Raffaella, Grossi, Micaela, Monda, Vincenzo, Cutrignelli, Monica I., Messina, Antonietta, Calabrò, Serena, Moni, Heleena B., Stradella, Luigi, Messina, Giovanni, Monda, Marcellino, Crispino, Marianna, and Mollica, Maria Pina
- Subjects
Male ,0301 basic medicine ,Animal feed ,Linoleic acid ,Conjugated linoleic acid ,redox status ,inflammatory status, mitochondrial function, n-6:n-3 ratio, redox status, Animals, Inflammation, Milk, Mitochondria, Dairying, Dietary Supplements, Oxidative Stress ,medicine.disease_cause ,03 medical and health sciences ,chemistry.chemical_compound ,mitochondrial function ,inflammatory status ,n-6:n-3 ratio ,Genetics ,medicine ,Animals ,Food science ,Rats, Wistar ,Dietary Supplement ,Inflammation ,Adiponectin ,redox statu ,Animal ,Chemistry ,Leptin ,0402 animal and dairy science ,food and beverages ,Oxidative Stre ,Lipid metabolism ,04 agricultural and veterinary sciences ,Animal Feed ,040201 dairy & animal science ,Rats ,Mitochondria ,Dairying ,Oxidative Stress ,030104 developmental biology ,Human nutrition ,Milk ,Dietary Supplements ,Rat ,Cattle ,Female ,Animal Science and Zoology ,inflammatory statu ,Oxidative stress ,Food Science - Abstract
Excessive energy intake may evoke complex biochemical processes characterized by inflammation, oxidative stress, and impairment of mitochondrial function that represent the main factors underlying noncommunicable diseases. Because cow milk is widely used for human nutrition and in food industry processing, the nutritional quality of milk is of special interest with respect to human health. In our study, we analyzed milk produced by dairy cows fed a diet characterized by a high forage:concentrate ratio (high forage milk, HFM). In view of the low n-6:n-3 ratio and high content of conjugated linoleic acid of HFM, we studied the effects of this milk on lipid metabolism, inflammation, mitochondrial function, and oxidative stress in a rat model. To this end, we supplemented for 4 wk the diet of male Wistar rats with HFM and with an isocaloric amount (82 kJ, 22 mL/d) of milk obtained from cows fed a diet with low forage:concentrate ratio, and analyzed the metabolic parameters of the animals. Our results indicate that HFM may positively affect lipid metabolism, leptin:adiponectin ratio, inflammation, mitochondrial function, and oxidative stress, providing the first evidence of the beneficial effects of HFM on rat metabolism.
- Published
- 2018
4. Regression of ovarian enlargement in pharmacological ovulation induction
- Author
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G. Pierno, E. Pecori, F. M. Severi, L. Stradella, Luigi Cobellis, E. De Lucia, Felice Petraglia, Cobellis, Luigi, Pecori, E, DE LUCIA, E, Pierno, G, Stradella, L, Severi, Fm, and Petraglia, F.
- Subjects
Adult ,OHSS ,Ovarian Regression ,Ovulation Induction ,Pharmacological ,medicine.medical_specialty ,Time Factors ,Endocrinology, Diabetes and Metabolism ,media_common.quotation_subject ,medicine.medical_treatment ,Ovarian hyperstimulation syndrome ,Physiology ,Fertilization in Vitro ,Group B ,Ovarian Hyperstimulation Syndrome ,Endocrinology ,Obstetrics and gynaecology ,Humans ,Medicine ,Ovulation ,Ultrasonography ,media_common ,Gynecology ,In vitro fertilisation ,Estradiol ,business.industry ,Incidence (epidemiology) ,Ovary ,Obstetrics and Gynecology ,medicine.disease ,Polycystic ovary ,Infertility ,Female ,Ovulation induction ,business ,Polycystic Ovary Syndrome - Abstract
The aim of the present study was to determine a possible relationship between ovarian functionality and regression of ovarian enlargement according to the different categories and degree of severity of ovarian hyperstimulation syndrome (OHSS). Among a group of sterile woman (n = 111), two subgroups were studied: group A (n = 15), patients affected by severe syndrome; and group B (n = 96), patients with massive ovarian enlargement only. The protocol of ovarian stimulation was conducted in various in vitro fertilization (IVF) centers; ultrasonographic examination and hematological checks were carried out daily; patients with severe OHSS were hospitalized. In women of group A, severe symptoms disappeared in 7-11 days; in nine patients with regular cycles ovary size returned to normal in about 30-40 days, whereas in six subjects with anovulatory cycles, the resolution was recorded in about 50-60 days; serum estradiol returned to physiological levels within 20-30 days. Women of group B showed a spontaneous regression at different times: in 43 subjects that presented regular ovulatory cycles, the resolution was recorded in about 30-40 days, whereas in 36 women with anovulatory cycles before pharmacological induction, resolution occurred in 50-60 days, and in 17 cases with polycystic ovary syndrome before pharmacological ovulation, an incomplete resolution was obtained; serum estradiol levels returned to a physiological range within 20-30 days. Our results show that in patients with regular ovulatory cycles, resolution of symptoms is obtained in a shorter time than in patients with anovulatory cycles before pharmacological induction.
- Published
- 2001
5. Screening for trisomy 21 by maternal age fetal nuchal translucency thickness and maternal serum sample
- Author
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M, Torella, B, Tormettino, V, Zurzolo, D, Labriola, D, Ambrosio, L, Stradella, M T, Schettino, and P, De Franciscis
- Subjects
Humans ,Pregnancy-Associated Plasma Protein-A ,Chorionic Gonadotropin, beta Subunit, Human ,Down Syndrome ,Nuchal Translucency Measurement ,Maternal Age - Abstract
The aim of this paper was to examine the performance of two-stage first-trimester combined screening based on maternal age, fetal nuchal translucency (NT) thickness and maternal serum sample "free beta-human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein-A (PAPP-A)".A combined screening for chromosomal anomalies was performed in 713 singleton pregnancies. We performed a two-stage screening with the blood taken at 8+0 to 10+6 weeks and the measurement of NT performed at 12+0 to 12+6 weeks. The maternal age related risk for trisomy 21 was calculated and adjusted according to the gestational age at the time of screening to derive the a-priori risk. The measured free beta-human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein-A (PAPP-A) were converted into a multiple of the median (MoM) for gestational age, adjusted for maternal weight, smoking status, ethnicity, method of conception (spontaneous or IVF) and parity. The measured NT was assessed in relationship of mesasure of CRL. Finally, the risk resulting by NT thickness and biochemical markers were multiplied by the a-priori risk to derive the patient-specific risk.The ultrascreen was considered positive in the case where the risk was greater than 1:250. In this case it was suggested the study of the fetal karyotype through an invasive test. In our study we had 23 positive cases after the combined screening: all patients have opted for the study of fetal karyotype, and in 5 cases the result was abnormal (trisomy 21). We had 1 case where the test was negative but the fetal karyotype was abnormal (trisomy 21). We have calculated sensitivity and false positive rate of the test.In our study there were 707 cases with a normal karyotype or delivery of a phenotypically normal baby and 6 cases with trisomy 21. The detection rate of the first trimester screening for chromosomal anomalies was 83% with a false positive rate of 3,2%. The aim of the study was estimated the performance of two-step strategy screening. In our study, the performance of the screening model, based on the two-stage, was not higher than the performance of screening based on a single-step reported in literature. In our opinion, there is no potential advantage in terms of detection rate.
- Published
- 2013
6. ['Rapid' cesarean section according to Stark: personal modifications]
- Author
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L, Stradella, E, Gioino, F, La Rezza, and A, Granata
- Subjects
Pregnancy Complications ,Time Factors ,Cesarean Section ,Pregnancy ,Humans ,Female - Published
- 2008
7. Ovarian hyperstimulation syndrome: distinction between local and systemic disease
- Author
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Giovanni Cobellis, E Pecori, L Stradella, Luigi Cobellis, Messalli Em, E. De Lucia, Cobellis, Luigi, Pecori, E, Stradella, L, DE LUCIA, E, Messalli, Enrico Michelino, and Cobellis, G.
- Subjects
Adult ,medicine.medical_specialty ,Systemic disease ,Menotropins ,Endocrinology, Diabetes and Metabolism ,media_common.quotation_subject ,medicine.medical_treatment ,Ovarian hyperstimulation syndrome ,Hematocrit ,Chorionic Gonadotropin ,Gonadotropin-Releasing Hormone ,Endocrinology ,Ovulation Induction ,Internal medicine ,Ascites ,Humans ,Medicine ,Ovulation ,Retrospective Studies ,media_common ,Gynecology ,Respiratory Distress Syndrome ,medicine.diagnostic_test ,business.industry ,Ovary ,Obstetrics and Gynecology ,Retrospective cohort study ,medicine.disease ,Creatinine ,Female ,Ovulation induction ,Follicle Stimulating Hormone ,medicine.symptom ,business ,Complication - Abstract
The ovarian hyperstimulation syndrome (OHSS) is an iatrogenic, unpredictable and potentially life-threatening complication in patients submitted to pharmacological ovarian stimulation. Information on risk factors, etiopathogenetic mechanisms, prevention strategies and therapeutic management is continuously updated. The present study retrospectively analyzed 123 women affected by different grades of OHSS as a result of pharmacological ovulation induction. Hospital admission was suggested in 14 patients with severe OHSS, whereas patients with moderate or mild OHSS were followed in the out-patient section of our department. The results confirmed the efficacy of the therapeutic scheme adopted. The syndrome is localized to the ovaries at the time that the condition is triggered; when organs different from the ovaries become involved, OHSS assumes systemic aspects. The different clinical signs are the basis of a proposal of a local and systemic classification.
- Published
- 2003
8. [Myomectomy during cesarean section and outside pregnancy. Different outcomes of scars]
- Author
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L, Cobellis, E M, Messali, L, Stradella, E, Pecori, E, Gioino, E, De Lucia, G, Cobellis, Cobellis, Luigi, Messali, Em, Stradella, L, Pecori, E, Gioino, E, DE LUCIA, E, and Cobellis, G.
- Subjects
Adult ,Cicatrix ,Cesarean Section ,Myometrium ,Humans ,Female - Abstract
The purpose of this study is the comparison between the scar of myomectomy performed during cesarean section and out of the pregnancy.Eighteen pregnant patients were submitted to cesarean section between 37 and 39 weeks of gestation for previous myomectomy. The previous myomectomy has been performed in 8 patients during a cesarean section, in 10 patients out of pregnancy; in all patients only one subserous-intramural myoma of uterine fundus or body with a maximum diameter of 4-5 cm has been excised.In myomectomies performed during cesarean section the scar appeared more linear, with good well defined limits, less wide and with modest introflection in comparison to surrounding myometrium. The myometrial thickness did not present variations and was well contracted.Our results show substantial differences: in fact, according to personal opinion, the different evolution of the healing process is due to variations occurring in pregnancy and particularly for local immunology system which in pregnancy is hyperactive. The presence and increased synthesis of immunological substances support a better healing with an optimal functional recovery.
- Published
- 2002
9. Electro-cautery of myomas during caesarean section—two case reports
- Author
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Luigi Cobellis, Giovanni Cobellis, Messalli Em, L Stradella, Pasquale Florio, Eugenio De. Lucia, and Felice Petraglia
- Subjects
Adult ,medicine.medical_specialty ,Uterine fibroids ,medicine.medical_treatment ,Electro-cautery ,Pregnancy ,Electrocoagulation ,Humans ,Medicine ,Caesarean section ,Myoma ,Leiomyoma ,Contraindication ,Ultrasonography ,Cesarean Section ,business.industry ,Obstetrics and Gynecology ,medicine.disease ,female genital diseases and pregnancy complications ,Surgery ,Reproductive Medicine ,Uterine Neoplasms ,Cauterization ,Female ,business ,Pregnancy Complications, Neoplastic - Abstract
Myomectomy is a surgical procedure not usually performed during caesarean section because associated with high risk of haemorrhage and other complications. The goal of our study is to evaluate the feasibility of myomectomy during caesarean section, the outcome, and try to establish the favourable conditions to perform a myomectomy during the same surgical event. Electro-cautery of intramural-subserous myomas was performed on two different patients. Only the myomas of little or middle size were treated. Both patients had multiple fibroids, a firm contraindication for myomectomy during caesarean section. After 10 and 13 months since myoma electro-cautery, all uterine fibroids treated were completely reabsorbed. These preliminary results regard the fibroids of middle size. It could be interesting evaluating the electro-cautery on bigger fibroids.
- Published
- 2002
10. Ultrasound diagnosis and Doppler monitoring of a pelvic spleen in pregnancy
- Author
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Fernando M. Reis, Filiberto Maria Severi, F. Di Pietto, L Stradella, L. Di Pietto, Luigi Cobellis, and Felice Petraglia
- Subjects
medicine.medical_specialty ,Pregnancy ,Radiological and Ultrasound Technology ,medicine.diagnostic_test ,business.industry ,Gestational sac ,Ultrasound ,Uterus ,Obstetrics and Gynecology ,Physical examination ,General Medicine ,Laser Doppler velocimetry ,medicine.disease ,Surgery ,medicine.anatomical_structure ,Reproductive Medicine ,Medicine ,Gestation ,Radiology, Nuclear Medicine and imaging ,Radiology ,Differential diagnosis ,business - Abstract
We describe a patient with a pelvic spleen diagnosed during pregnancy and monitored through gestation which we believe to be the first reported case. A 40-year-old woman was referred at 8 weeks of gestation because of a chronic intense pain in the left iliac cavity which had spread to her lower back. Clinical examination revealed a poorly defined pelvic mass. Pelvic ultrasound demonstrated a gestational sac containing a viable embryo whose size was consistent with the period of amenorrhea. While the splenic area in the left hypocondrium was found to be empty, a homogeneous and elongate mass measuring 152 x 123 mm with a maximum thickness of 53.4 mm was observed in the left iliac cavity above the uterus. This mass, the ectopic spleen, was monitored by Doppler velocimetry at monthly intervals until delivery and no variation throughout gestation was observed; therefore, despite the occasional occurrence of heavy pain, it was possible to exclude circulatory complications such as thrombosis or torsion. Doppler ultrasound proved to be a useful tool for the differential diagnosis of this rare anatomical variation.
- Published
- 2001
11. The influence of chemisorbed gases on the magnetization of transition metals
- Author
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E. Genova and L. Stradella
- Subjects
Magnetization ,Nickel ,Materials science ,Transition metal ,chemistry ,Hydrogen ,Chemisorption ,Inorganic chemistry ,chemistry.chemical_element ,General Materials Science ,Magnetic susceptibility ,Titanium ,Palladium - Published
- 1995
12. Calorimetric study of the acid-base properties of an oxidation catalyst
- Author
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L. Stradella
- Subjects
chemistry.chemical_classification ,Base (chemistry) ,Chemistry ,Inorganic chemistry ,General Engineering ,chemistry.chemical_element ,Molybdate ,Bismuth ,Catalysis ,chemistry.chemical_compound ,Adsorption ,Catalytic oxidation ,Carbon dioxide ,Carbon monoxide - Abstract
Calorimetric adsorption measurements of carbon monoxide and carbon dioxide have been performed on bismuth molybdate (2:1) at 300 K. The basicity of the sample is low and the adsorption of a ‘soft’ base such as carbon monoxide is small. On the other hand, the acidity titrated by a ‘hard’ base like ammonia is high. A kinetic and calorimetric study has shown that a CO-O 2 mixture may interact at 300 K on the molybdate surface.
- Published
- 1988
13. Calorimetric study of dinitrogen adsorption at 310 K on a chromia/silica catalyst
- Author
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L. Stradella
- Subjects
Adsorption ,Chemistry ,Energetics ,Inorganic chemistry ,Calorimetry ,Physical and Theoretical Chemistry ,Catalysis ,Chromia - Abstract
The energetics of dinitrogen adsorption on 310 K on a chromia catalyst has been investigated by adsorption calorimetry. Two types of heats have been detected and assigned to a least two different interactions with CrII sites of the catalyst.
- Published
- 1985
14. Energetics of the adsorption-desorption cycles of oxygen on a titania-based catalyst
- Author
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L. Stradella
- Subjects
Exothermic reaction ,Adsorption ,Chemisorption ,Chemistry ,Desorption ,Energetics ,Inorganic chemistry ,General Engineering ,Molecule ,chemistry.chemical_element ,Oxygen ,Catalysis - Abstract
The adsorption-desorption of oxygen on pure TiO2 and RuO2-loaded TiO2 has been investigated at 305 K by means of a microcalorimetric technique. On pure TiO2the oxygen is adsorbed reversibly, and the differential heat suggests that the process proceeds through physically adsorbed molecules; loading with RuO2 causes irreversible O2 chemisorption at low pressure while, at higher pressure, a process similar to that observed on pure TiO2 occurs. The heats of exothermic desorption in the case of the loaded specimen may be interpreted by assuming the surface recombination of atomic oxygen.
- Published
- 1984
15. Energetics of the interaction of hydrogen with loaded titanium dioxide
- Author
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L. Stradella and E. Pelizzetti
- Subjects
Isothermal microcalorimetry ,Hydrogen ,Chemistry ,Diffusion ,Inorganic chemistry ,General Engineering ,chemistry.chemical_element ,Catalysis ,Metal ,chemistry.chemical_compound ,Adsorption ,visual_art ,Desorption ,Titanium dioxide ,visual_art.visual_art_medium - Abstract
The heats of adsorption and desorption of hydrogen on a loaded titanium dioxide have been measured at 300 K by means of a Tian Calvet microcalorimeter. Differential heats of adsorption in the first run decrease from 40 to 3.5 kJ mol−1. Irreversibly adsorbed hydrogen is detected in all the adsorption-desorption cycles. Desorption shows differential heats that are always greater than the corresponding adsorption ones. Thermokinetic observations indicate diffusion of the adsorbate into the TiO2 structure.
- Published
- 1986
16. Etude par thermogravimétrie et par calorimétrie différentielle de la réduction et réoxydation des molybdates de bismuth (2:1, 2:3)
- Author
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V. Bolis and L. Stradella
- Subjects
Biochemistry - Abstract
Il a ete poursuivi par thermogravimetrie et par calorimetrie differentielle (DSC) une etude des reactions de reduction et de reoxydation de deux echantillons de molybdates de bismuth, le Bi2 O3 · MoO3 et le Bi2 O3 · 3MoO3 .Ces mesures nous ont permis de mettre en evidence differentes energies d'activation au fur et a mesure que la reaction avec l'hydrogene se produit.Au moins trois sites de reoxydation ont ete ainsi detectes par DSC. De ces thermogrammes on peut aussi obtenir le dosage du bismuth metallique produit pendant la reduction.
- Published
- 1984
17. TG and DTA study of oxygen depletion and reoxidation of bismuth molybdates (2∶1;2∶3)
- Author
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L. Stradella
- Subjects
Thermogravimetry ,Arrhenius equation ,symbols.namesake ,chemistry ,Inorganic chemistry ,Kinetics ,symbols ,chemistry.chemical_element ,Activation energy ,Oxygen ,Deoxygenation ,Isothermal process ,Bismuth - Abstract
Oxygen depletion and reoxidation of bismuth molybdates (2∶1; 2∶3) have been studied by means of isothermal thermogravimetry and DTA measurements. From the isothermal curves, Arrhenius energies were obtained between 411 and 683 K. The activation energies for oxygen depletion from Bi2O3·MoO3 were lower than those for Bi2O3·3MoO3. Two kinetically different types of oxygen release were identified for both molybdates. Arrhenius plots were also obtained from reoxidation experiments: Bi2O3·MoO3 was more easily reoxidable than Bi2O3·3MoO3. The substantial closeness of the respective activation energies suggests that depletion and reoxidation follow the same mechanistic steps.
- Published
- 1984
18. Calorimetric study of the kinetics of adsorption of hydrogen loaded titanium oxide
- Author
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L. Stradella
- Subjects
Isothermal microcalorimetry ,Hydrogen ,Inorganic chemistry ,Kinetics ,chemistry.chemical_element ,Titanium oxide ,Metal ,chemistry.chemical_compound ,Thermokinetics ,Adsorption ,chemistry ,visual_art ,Titanium dioxide ,visual_art.visual_art_medium - Abstract
The thermokinetics of the adsorption of hydrogen on a loaded titanium dioxide has been studied by microcalorimetry.
- Published
- 1988
19. Selective Adsorption of n-Fatty Acids (C4-C12-C18) at the Alumina/n-Heptane Interface: Adsorption Isotherms and Heats of Displacement
- Author
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G. Venturello and L. Stradella
- Subjects
Heptane ,Hydrogen bond ,General Chemical Engineering ,chemistry.chemical_compound ,symbols.namesake ,Adsorption ,chemistry ,Selective adsorption ,symbols ,Molecular symmetry ,Organic chemistry ,Molecule ,Physical chemistry ,Carboxylate ,van der Waals force - Abstract
The isotherms and the heats of selective adsorption of n-fatty acids (C4, C12, C18) at the alumina/n-heptane interface have been determined at 313 K. All adsorption isotherms show stepwise trend of the L-4 type isotherm according to Gile's classification. This behaviour has been interpreted assuming progressive rearrangement in the adsorbed layer with partial formation of dimers of n-fatty acid molecules in correspondence of high surface coverage. – As the monocarboxylic acid orientation is concerned limiting adsorption from n-heptane is consistent with the hypothesis of the surface structure made up of symmetric bidentate carboxylate ions, with the molecular symmetry axis rotating away from the perpendicular, orientation. – Studying the effects of the sample outgassing temperature upon the differential heats of adsorption, one may assume that: i)At T ≤ 573 K the differential heats are typical of hydrogen bonding between fatty acids' carboxylic group and isolated surface hydroxyls groups. ii)At higher outgassing temperatures the heats of selective adsorption are representative of dissociative chemisorption on c.u.s. sites. In correspondence of higher surface coverages aspecific Van der Waals interactions become prevalent. – The differential heats of adsorption for all η- and α-alumina samples decrease as the chain length increases. – α-Al2O3 differential heats are smaller than η-Al2O3 adsorption heats.
- Published
- 1983
20. Calorimetric study of adduct formation at 300 K between H2Os3(CO)10 and Lewis bases
- Author
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L. Stradella
- Subjects
Isothermal microcalorimetry ,chemistry.chemical_compound ,Chloroform ,Thermokinetics ,Chemistry ,Ligand ,Steric factor ,Enthalpy ,Physical chemistry ,Organic chemistry ,Lewis acids and bases ,Adduct - Abstract
The enthalpies of the reactions H2Os3(CO)10(I)+L=H2Os3(CO)10L(II),L=PR3, P(OR)3, in chloroform were determined by means of microcalorimetry. Satisfactory agreement was found between the basicity parameters and the measured reaction enthalpies. As concerns the kinetics, qualitative correlation of a thermokinetics parameter with the steric factor of the ligand was observed.
- Published
- 1986
21. Calorimetric Study Of Adsorption Of Ammonia At 420 K On Bismuth Molybdate (2:1)
- Author
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L. Stradella
- Subjects
chemistry.chemical_compound ,Ammonia ,Adsorption ,chemistry ,Inorganic chemistry ,Irreversible adsorption ,chemistry.chemical_element ,Fraction (chemistry) ,Surface concentration ,Molybdate ,Stoichiometry ,Bismuth - Abstract
Adsorption-desorption cycles of ammonia on Bi2O3-MoO3 samples, reduced or almost stoichiometric, have been performed at 420 K by means of a microcalorimeter. Practically irreversible adsorption of ammonia occurs on the reduced specimen which shows a fraction of highly energetic sites (qdiff 150 kJ/mol). The surface concentration of such sites seems however the same on both samples.
- Published
- 1985
22. Gigantomastia During Pregnancy Due to Burkitt Lymphoma.
- Author
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Foreste V, Della Corte L, Stradella C, Cusati B, Coco G, and Stradella L
- Abstract
Gigantomastia is a rare complication of pregnancy usually associated with benign conditions and rarely with malignancies. This paper reports a non-Hodgkin lymphoma case associated with gigantomastia during pregnancy. The patient was a 30-year-old gravida one woman, with a history of rapidly enlarging right breast at 2 weeks prior to presentation. After the first diagnosis of benign gigantomastia, the continuous growth of the breast, despite the delivery and bromocriptine therapy, required further investigation of the case. The histological analysis revealed the presence of Burkitt lymphoma. Malignant causes of unilateral gigantomastia in pregnancy should be considered in the differential diagnosis of this condition., Competing Interests: Conflict of Interest: The authors have no conflicts of interest to declare., (©Copyright 2021 by Turkish Federation of Breast Diseases Associations.)
- Published
- 2020
- Full Text
- View/download PDF
23. Milk from cows fed a diet with a high forage:concentrate ratio improves inflammatory state, oxidative stress, and mitochondrial function in rats.
- Author
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Cavaliere G, Trinchese G, Musco N, Infascelli F, De Filippo C, Mastellone V, Morittu VM, Lombardi P, Tudisco R, Grossi M, Monda V, Cutrignelli MI, Messina A, Calabrò S, Moni HB, Stradella L, Messina G, Monda M, Crispino M, and Mollica MP
- Subjects
- Animals, Cattle, Female, Inflammation prevention & control, Male, Rats, Rats, Wistar, Animal Feed analysis, Dairying, Dietary Supplements, Inflammation therapy, Milk chemistry, Mitochondria physiology, Oxidative Stress
- Abstract
Excessive energy intake may evoke complex biochemical processes characterized by inflammation, oxidative stress, and impairment of mitochondrial function that represent the main factors underlying noncommunicable diseases. Because cow milk is widely used for human nutrition and in food industry processing, the nutritional quality of milk is of special interest with respect to human health. In our study, we analyzed milk produced by dairy cows fed a diet characterized by a high forage:concentrate ratio (high forage milk, HFM). In view of the low n-6:n-3 ratio and high content of conjugated linoleic acid of HFM, we studied the effects of this milk on lipid metabolism, inflammation, mitochondrial function, and oxidative stress in a rat model. To this end, we supplemented for 4 wk the diet of male Wistar rats with HFM and with an isocaloric amount (82 kJ, 22 mL/d) of milk obtained from cows fed a diet with low forage:concentrate ratio, and analyzed the metabolic parameters of the animals. Our results indicate that HFM may positively affect lipid metabolism, leptin:adiponectin ratio, inflammation, mitochondrial function, and oxidative stress, providing the first evidence of the beneficial effects of HFM on rat metabolism., (Copyright © 2018 American Dairy Science Association. Published by Elsevier Inc. All rights reserved.)
- Published
- 2018
- Full Text
- View/download PDF
24. Pregnancy management in Behçet's disease treated with uninterrupted infliximab. Report of a case with fetal growth restriction and mini-review of the literature.
- Author
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Mainini G, Di Donna MC, Esposito E, Ercolano S, Correa R, Stradella L, Della Gala A, and De Franciscis P
- Subjects
- Anticoagulants therapeutic use, Enoxaparin therapeutic use, Female, Humans, Infant, Newborn, Infliximab, Labor, Induced, Male, Pregnancy, Pregnancy Trimester, Third, Anti-Inflammatory Agents, Non-Steroidal therapeutic use, Antibodies, Monoclonal therapeutic use, Behcet Syndrome drug therapy, Fetal Growth Retardation drug therapy, Pregnancy Complications drug therapy
- Abstract
Background: The mutual impact of Behçet's disease (BD) and pregnancy is variable and still unclear. Among the safe drugs administered, the newer infliximab (IFX) was rarely experienced in pregnancy, particularly in the third trimester., Case: The authors report a pregnancy with fetal growth restriction at 36 weeks in a 31-year-old primigravida with symptomatic BD, treated with uninterrupted monthly IFX and daily enoxaparin. The patient was induced at 38 weeks and had an uneventful vaginal delivery of a healthy baby. The postpartum period and following six months were uneventful for mother in terms of BD exacerbation, and newborn in terms of potential risks of neonatal BD and/or infections due to late immunosuppressive IFX administration., Conclusion: Because of the inconstant mutual impact, BD pregnancies should be precautionary considered at "potential high-risk" and need a careful and close monitoring by a multidisciplinary team with specific expertise.
- Published
- 2014
25. Screening for trisomy 21 by maternal age fetal nuchal translucency thickness and maternal serum sample.
- Author
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Torella M, Tormettino B, Zurzolo V, Labriola D, Ambrosio D, Stradella L, Schettino MT, and De Franciscis P
- Subjects
- Chorionic Gonadotropin, beta Subunit, Human, Humans, Maternal Age, Pregnancy-Associated Plasma Protein-A, Down Syndrome, Nuchal Translucency Measurement
- Abstract
Aim: The aim of this paper was to examine the performance of two-stage first-trimester combined screening based on maternal age, fetal nuchal translucency (NT) thickness and maternal serum sample "free beta-human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein-A (PAPP-A)"., Methods: A combined screening for chromosomal anomalies was performed in 713 singleton pregnancies. We performed a two-stage screening with the blood taken at 8+0 to 10+6 weeks and the measurement of NT performed at 12+0 to 12+6 weeks. The maternal age related risk for trisomy 21 was calculated and adjusted according to the gestational age at the time of screening to derive the a-priori risk. The measured free beta-human chorionic gonadotropin (β-hCG) and pregnancy-associated plasma protein-A (PAPP-A) were converted into a multiple of the median (MoM) for gestational age, adjusted for maternal weight, smoking status, ethnicity, method of conception (spontaneous or IVF) and parity. The measured NT was assessed in relationship of mesasure of CRL. Finally, the risk resulting by NT thickness and biochemical markers were multiplied by the a-priori risk to derive the patient-specific risk., Results: The ultrascreen was considered positive in the case where the risk was greater than 1:250. In this case it was suggested the study of the fetal karyotype through an invasive test. In our study we had 23 positive cases after the combined screening: all patients have opted for the study of fetal karyotype, and in 5 cases the result was abnormal (trisomy 21). We had 1 case where the test was negative but the fetal karyotype was abnormal (trisomy 21). We have calculated sensitivity and false positive rate of the test., Conclusion: In our study there were 707 cases with a normal karyotype or delivery of a phenotypically normal baby and 6 cases with trisomy 21. The detection rate of the first trimester screening for chromosomal anomalies was 83% with a false positive rate of 3,2%. The aim of the study was estimated the performance of two-step strategy screening. In our study, the performance of the screening model, based on the two-stage, was not higher than the performance of screening based on a single-step reported in literature. In our opinion, there is no potential advantage in terms of detection rate.
- Published
- 2013
26. Nonhormonal management of postmenopausal women: effects of a red clover based isoflavones supplementation on climacteric syndrome and cardiovascular risk serum profile.
- Author
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Mainini G, Torella M, Di Donna MC, Esposito E, Ercolano S, Correa R, Cucinella G, Stradella L, Luisi A, Basso A, Cerreto FV, Cicatiello R, Matteo M, and De Franciscis P
- Subjects
- Cardiovascular Diseases blood, Female, Humans, Middle Aged, Phytoestrogens therapeutic use, Phytotherapy, Risk Assessment, Cardiovascular Diseases epidemiology, Hot Flashes drug therapy, Isoflavones therapeutic use, Phytoestrogens administration & dosage, Trifolium
- Abstract
Purpose of Investigation: The aim of this prospective randomized study was to evaluate a red clover based isoflavones supplementation in the treatment of climacteric syndrome and its effects on cardiovascular risk serum profile., Materials and Methods: The study included 150 healthy postmenopausal women that were randomly assigned to receive phytoestrogens tablets, amounting in a total daily intake of 60.8 mg red clover isoflavones plus 19.2 mg soy isoflavones (n = 75), or placebo (n = 75). The authors evaluated teh following: daily number of hot flushes and Kupperman Index at baseline and after one and three months; serum total, high-density lipoprotein (HDL) and low-density lipoprotein (LDL) cholesterol, triglycerides, prothrombin time (PT), partial thromboplastin time (PTT), fibrinogen, and antithrombin III (ATIII) at baseline and after three and six months., Results: One hundred twenty-eight patients completed the study: 67 in the active group and 61 in the placebo group. The treatment led to a progressive significant reduction (p < 0.05) of the number of hot flushes in the active group compared to placebo already after one month, while Kupperman Index was statistically reduced after three months. No significant variation in total cholesterol, LDL-cholesterol, HDL-cholesterol, triglycerides, PT, PTT, fibrinogen, and ATIII were found., Conclusion: The present findings suggest that a red clover based isoflavones supplementation in healthy postmenopausal women is promptly effective on climacteric syndrome, improves neurovegetative symptoms, safe on cardiovascular risk serum profile, and does not modify lipids and coagulation.
- Published
- 2013
27. Clinical management of a pregnant woman with Takayasu's arteritis: case report.
- Author
-
Stradella L, Sabbadini M, Giordano V, Gioino E, La Rezza F, and Granata A
- Subjects
- Adult, Anti-Inflammatory Agents, Non-Steroidal therapeutic use, Anticoagulants therapeutic use, Carotid Arteries diagnostic imaging, Diagnosis, Differential, Drug Therapy, Combination, Female, Humans, Pregnancy, Pregnancy Complications, Cardiovascular diagnosis, Pregnancy Complications, Cardiovascular drug therapy, Prognosis, Subclavian Artery diagnostic imaging, Takayasu Arteritis diagnosis, Takayasu Arteritis drug therapy, Treatment Outcome, Ultrasonography, Pregnancy Complications, Cardiovascular diagnostic imaging, Takayasu Arteritis diagnostic imaging
- Published
- 2008
28. [''Rapid'' cesarean section according to Stark: personal modifications].
- Author
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Stradella L, Gioino E, La Rezza F, and Granata A
- Subjects
- Female, Humans, Pregnancy, Pregnancy Complications prevention & control, Time Factors, Cesarean Section methods
- Published
- 2008
29. Alcohol sclerotherapy: a new method for Bartholin gland cyst treatment.
- Author
-
Cobellis PL, Stradella L, De Lucia E, Iannella I, Pecori E, Scaffa C, Cobellis G, and Colacurci N
- Subjects
- Female, Humans, Bartholin's Glands pathology, Cysts pathology, Cysts therapy, Ethanol therapeutic use, Sclerosing Solutions therapeutic use, Sclerotherapy methods, Vulvar Diseases therapy
- Abstract
Aim: Bartholin gland cysts are one of the most common gynecologic problems. Around 2% of women suffer from these pathologies. Bartholin gland cyst are generally asymptomatic, but sometimes extremely painful to restrict physical activity. The treatment choice is related to the patient's age, the size of the cyst or abscess and relapses, but different approaches are possible. The aim of this study is to investigate the efficicacy and safety of the alcohol sclerotherapy versus the only aspiration to cure symptomatic cysts or abscesses of the Bartholin's gland., Methods: Between January 2002 and June 2004, 18 patients suffering from Bartholin symptomatic unilateral cysts or with abscess are selected. These patients have been divided into 2 groups and they have been treated with alcohol sclerotherapy or aspiration. The simple aspiration removes only the cyst fluid. The alcohol sclerotherapy allows to destroy the epithelial covering of the cyst by a coagulative necrosis and then a fibrosis which covers the cavity and prevents the reformation of liquid., Results: Treatment has been satisfactory for all the patients, and treatment time has been shorter with alcohol sclerotherapy. None of the patients, in both groups, presented sexual dysfunctions or dyspareunia., Conclusions: Alcohol sclerotherapy might be an ideal and safe procedure in the treatment of the Bartholin's gland or abscesses with a low percentage of relapses.
- Published
- 2006
30. Methotrexate treatment for tubal pregnancy. Criteria for medical approach.
- Author
-
Cobellis G, Pierno G, Pecori E, Scaffa C, Stradella L, Messalli EM, Festa B, and Cobellis L
- Subjects
- Adult, Chorionic Gonadotropin blood, Female, Humans, Laparoscopy, Patient Selection, Pregnancy, Retrospective Studies, Abortifacient Agents, Nonsteroidal therapeutic use, Methotrexate therapeutic use, Pregnancy, Tubal drug therapy
- Abstract
Aim: The purpose of this retrospective study is to underline the indications for the use of systemic methotrexate (MTX) in tubal pregnancies., Methods: One hundred and four (n=104) consecutive women were treated in our Department for tubal pregnancy. The database analysis showed that after careful respect for inclusion criteria, the treatment chosen was the intravenous administration of MTX in 68 patients, whereas laparoscopy constituted the primary treatment in 36 patients. A single dose of MTX was intravenously administered, diluted in saline solution, with a dosage of 50 mg/m2 of body surface. Close serum beta-hCG monitoring was performed, and in the case of a short fall, a 2nd dose of methotrexate was submitted., Results: The overall success rate of MTX treatment was 91%; the 2nd dose of MTX was used in 12% of patients, whereas in only 6 out of 68 patients included in the medical treatment group a surgical approach for suspected tubal rupture was necessary., Conclusion: Treatment with methotrexate is effective and safe in the presence of these criteria: patient hemodynamically stable, absence of tubal rupture sign and hemoperitoneum, an adnexal mass with a diameter < or = 5 cm, an amenorrhea < or = 6 weeks and HCG levels < or = 10,000 mIU/ml. Laparoscopy is indicated in diagnostic uncertainty, when MTX is not suggested, when adnexal mass is > 5 cm, or in patients in which beta-hCG levels was > 10,000 mIU/ml.
- Published
- 2003
31. Alcohol sclerosis of endometriomas after ultrasound-guided aspiration.
- Author
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Messalli EM, Cobellis G, Pecori E, Pierno G, Scaffa C, Stradella L, and Cobellis L
- Subjects
- Adolescent, Adult, Biopsy, Needle methods, Female, Follow-Up Studies, Humans, Ultrasonography, Endometriosis diagnostic imaging, Endometriosis therapy, Ethanol, Sclerotherapy
- Abstract
Aim: We investigate the possibility to use ultrasound-guided aspiration and alcohol sclerosis in patients with endometrioma., Methods: Ten patients with endometriotic ovarian cysts, mean diameter <70 mm, CA125 <35 UI, persistence of cyst after medical therapy and refusal of surgical therapy have been studied. The patients were submitted to ultrasound-guided aspiration of endometriomas. Fifty per cent of aspirated fluid was replaced with pure ethanol, which was left in situ for 10 to 20 minutes. No medical therapy was employed after aspiration and ethanol treatment., Results: In 9 patients no recurrence was observed at ultrasound after 21.2+/-6.62 months of follow-up. In 1 case only, after 6 months, a recurrence of the endometrioma in the same site was observed., Conclusion: Ultrasound-guided alcoholic sclerotherapy of the endometriotic ovarian cysts is effective and safe. We speculate that this procedure could be indicated in patients refusing standard surgical therapy.
- Published
- 2003
32. [Spontaneous rupture of the spleen in pregnancy].
- Author
-
Cobellis L, Stradella L, Pecori E, and Cobellis G
- Subjects
- Adult, Female, Humans, Pregnancy, Rupture, Spontaneous, Pregnancy Complications diagnosis, Splenic Rupture diagnosis
- Published
- 2003
33. Ovarian hyperstimulation syndrome: distinction between local and systemic disease.
- Author
-
Cobellis L, Pecori E, Stradella L, De Lucia E, Messalli EM, and Cobellis G
- Subjects
- Adult, Ascites, Chorionic Gonadotropin administration & dosage, Creatinine blood, Female, Follicle Stimulating Hormone administration & dosage, Gonadotropin-Releasing Hormone analogs & derivatives, Hematocrit, Humans, Menotropins administration & dosage, Ovarian Hyperstimulation Syndrome diagnosis, Ovarian Hyperstimulation Syndrome etiology, Ovary pathology, Ovulation Induction adverse effects, Respiratory Distress Syndrome, Retrospective Studies, Ovarian Hyperstimulation Syndrome classification
- Abstract
The ovarian hyperstimulation syndrome (OHSS) is an iatrogenic, unpredictable and potentially life-threatening complication in patients submitted to pharmacological ovarian stimulation. Information on risk factors, etiopathogenetic mechanisms, prevention strategies and therapeutic management is continuously updated. The present study retrospectively analyzed 123 women affected by different grades of OHSS as a result of pharmacological ovulation induction. Hospital admission was suggested in 14 patients with severe OHSS, whereas patients with moderate or mild OHSS were followed in the out-patient section of our department. The results confirmed the efficacy of the therapeutic scheme adopted. The syndrome is localized to the ovaries at the time that the condition is triggered; when organs different from the ovaries become involved, OHSS assumes systemic aspects. The different clinical signs are the basis of a proposal of a local and systemic classification.
- Published
- 2003
34. [Pelvic actinomycosis and sub-acute abdomen].
- Author
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Messalli EM, Cobellis L, Festa B, Pecori E, Stradella L, and Cobellis G
- Subjects
- Adult, Female, Humans, Abdomen, Acute etiology, Abdominal Abscess complications, Actinomycosis complications
- Abstract
An interesting case of pelvic actinomycosis with paculiar clinical manifestation is presented. A 42 years-old patient came to our emergency service for an abdominal pelvic pain and fever. Past history showed IUD in situ for over 15 years. The patient was submitted to a ultrasonographic scan and a complete hematological screening was performed. The diagnosis was of subacute abdomen, and an exploratory laparotomy was carried out. During laparotomy an atypical reactive tissue and a suppurative cavity were found. The histological finding of tissue biopsy showed pelvic actinomycosis. On the basis of these findings the conclusion is drawn that a better prevention of pelvic actinomycosis is necessary of its diffusion in the last years due to sexual habit changes.
- Published
- 2002
35. [Myomectomy during cesarean section and outside pregnancy. Different outcomes of scars].
- Author
-
Cobellis L, Messali EM, Stradella L, Pecori E, Gioino E, De Lucia E, and Cobellis G
- Subjects
- Adult, Female, Humans, Cesarean Section, Cicatrix, Myometrium surgery
- Abstract
Background: The purpose of this study is the comparison between the scar of myomectomy performed during cesarean section and out of the pregnancy., Methods: Eighteen pregnant patients were submitted to cesarean section between 37 and 39 weeks of gestation for previous myomectomy. The previous myomectomy has been performed in 8 patients during a cesarean section, in 10 patients out of pregnancy; in all patients only one subserous-intramural myoma of uterine fundus or body with a maximum diameter of 4-5 cm has been excised., Results: In myomectomies performed during cesarean section the scar appeared more linear, with good well defined limits, less wide and with modest introflection in comparison to surrounding myometrium. The myometrial thickness did not present variations and was well contracted., Conclusions: Our results show substantial differences: in fact, according to personal opinion, the different evolution of the healing process is due to variations occurring in pregnancy and particularly for local immunology system which in pregnancy is hyperactive. The presence and increased synthesis of immunological substances support a better healing with an optimal functional recovery.
- Published
- 2002
36. Restitutio ad integrum of myometrium after myomectomy. Different results in pregnant and non-pregnant patients.
- Author
-
Cobellis G, Messalli EM, Stradella L, Pecori E, and Cobellis L
- Subjects
- Adult, Female, Humans, Hyperplasia, Hypertrophy, Pregnancy, Myometrium pathology, Myometrium surgery
- Abstract
Background: The aim of this study is to check whether there exists a difference in restitutio ad integrum of the uterus after myomectomy performed during Caesarean section and out of pregnancy., Methods: Two different groups are considered: Group A (n=8) that underwent myomectomy during Caesarean section; Group B (n=10) in which myomectomy was performed out of pregnancy. All patients were followed with serial scan evaluations., Results: The results showed a much more complete and faster absorption of hyperplasia and hypertrophy surrounding fibroid nodules when myomectomy was performed during Caesarean section., Conclusions: A later pregnancy in patients who underwent myomectomy during Caesarean section might have a favourable outcome, possibly reaching a term gestation and vaginal delivery.
- Published
- 2002
37. Electro-cautery of myomas during caesarean section--two case reports.
- Author
-
Cobellis L, Florio P, Stradella L, De Lucia E, Messalli EM, Petraglia F, and Cobellis G
- Subjects
- Adult, Female, Humans, Leiomyoma diagnostic imaging, Pregnancy, Ultrasonography, Uterine Neoplasms diagnostic imaging, Cesarean Section, Electrocoagulation, Leiomyoma surgery, Pregnancy Complications, Neoplastic surgery, Uterine Neoplasms surgery
- Abstract
Myomectomy is a surgical procedure not usually performed during caesarean section because associated with high risk of haemorrhage and other complications. The goal of our study is to evaluate the feasibility of myomectomy during caesarean section, the outcome, and try to establish the favourable conditions to perform a myomectomy during the same surgical event. Electro-cautery of intramural-subserous myomas was performed on two different patients. Only the myomas of little or middle size were treated. Both patients had multiple fibroids, a firm contraindication for myomectomy during caesarean section. After 10 and 13 months since myoma electro-cautery, all uterine fibroids treated were completely reabsorbed. These preliminary results regard the fibroids of middle size. It could be interesting evaluating the electro-cautery on bigger fibroids.
- Published
- 2002
- Full Text
- View/download PDF
38. Regression of ovarian enlargement in pharmacological ovulation induction.
- Author
-
Cobellis L, Pecori E, De Lucia E, Pierno G, Stradella L, Severi FM, and Petraglia F
- Subjects
- Adult, Estradiol blood, Female, Humans, Infertility therapy, Ovarian Hyperstimulation Syndrome diagnostic imaging, Ovary diagnostic imaging, Polycystic Ovary Syndrome diagnostic imaging, Polycystic Ovary Syndrome pathology, Time Factors, Ultrasonography, Fertilization in Vitro, Ovarian Hyperstimulation Syndrome pathology, Ovary pathology, Ovulation Induction
- Abstract
The aim of the present study was to determine a possible relationship between ovarian functionality and regression of ovarian enlargement according to the different categories and degree of severity of ovarian hyperstimulation syndrome (OHSS). Among a group of sterile woman (n = 111), two subgroups were studied: group A (n = 15), patients affected by severe syndrome; and group B (n = 96), patients with massive ovarian enlargement only. The protocol of ovarian stimulation was conducted in various in vitro fertilization (IVF) centers; ultrasonographic examination and hematological checks were carried out daily; patients with severe OHSS were hospitalized. In women of group A, severe symptoms disappeared in 7-11 days; in nine patients with regular cycles ovary size returned to normal in about 30-40 days, whereas in six subjects with anovulatory cycles, the resolution was recorded in about 50-60 days; serum estradiol returned to physiological levels within 20-30 days. Women of group B showed a spontaneous regression at different times: in 43 subjects that presented regular ovulatory cycles, the resolution was recorded in about 30-40 days, whereas in 36 women with anovulatory cycles before pharmacological induction, resolution occurred in 50-60 days, and in 17 cases with polycystic ovary syndrome before pharmacological ovulation, an incomplete resolution was obtained; serum estradiol levels returned to a physiological range within 20-30 days. Our results show that in patients with regular ovulatory cycles, resolution of symptoms is obtained in a shorter time than in patients with anovulatory cycles before pharmacological induction.
- Published
- 2001
39. Ultrasound diagnosis and Doppler monitoring of a pelvic spleen in pregnancy.
- Author
-
Cobellis L, Di Pietto F, Di Pietto L, Stradella L, Reis FM, Severi FM, and Petraglia F
- Subjects
- Adult, Female, Humans, Pregnancy, Pregnancy Outcome, Spleen diagnostic imaging, Choristoma diagnostic imaging, Pelvis diagnostic imaging, Spleen abnormalities, Splenic Diseases diagnostic imaging, Ultrasonography, Doppler, Color
- Abstract
We describe a patient with a pelvic spleen diagnosed during pregnancy and monitored through gestation which we believe to be the first reported case. A 40-year-old woman was referred at 8 weeks of gestation because of a chronic intense pain in the left iliac cavity which had spread to her lower back. Clinical examination revealed a poorly defined pelvic mass. Pelvic ultrasound demonstrated a gestational sac containing a viable embryo whose size was consistent with the period of amenorrhea. While the splenic area in the left hypocondrium was found to be empty, a homogeneous and elongate mass measuring 152 x 123 mm with a maximum thickness of 53.4 mm was observed in the left iliac cavity above the uterus. This mass, the ectopic spleen, was monitored by Doppler velocimetry at monthly intervals until delivery and no variation throughout gestation was observed; therefore, despite the occasional occurrence of heavy pain, it was possible to exclude circulatory complications such as thrombosis or torsion. Doppler ultrasound proved to be a useful tool for the differential diagnosis of this rare anatomical variation.
- Published
- 2001
- Full Text
- View/download PDF
40. Contribution to the choice of therapy in abdominal pregnancy.
- Author
-
Cobellis L, Stradella L, and Messalli EM
- Subjects
- Adult, Female, Humans, Injections, Intravenous, Pregnancy, Antimetabolites, Antineoplastic therapeutic use, Methotrexate therapeutic use, Pregnancy, Abdominal drug therapy
- Abstract
The goal of our study was to offer our contribution to the selection of the most suitable therapy to treat abdominal pregnancy. We discuss three patients affected with this pathology, which was diagnosed early by laparoscopy. The patients were treated with 50 mg/m2 of methotrexate administered intravenously. The abdominal pregnancy was terminated in all three patients. Since the outcome involved termination of the pregnancy, it is important to emphasize that methotrexate therapy, must be considered elective. Operative laparoscopy can be limited only to cases in which the ovum has not become implanted in the intestinal interstices and is not near sites susceptible to complications.
- Published
- 2000
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