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Background and Objectives: Improving diversity in the physician workforce continues to be a challenge and a priority for medical schools. Establishing a school-wide mission statement that addresses diversity, equity, and inclusion can help support efforts to increase the number of underrepresented in medicine (URM) graduates. Methods: In this study, we analyzed changes in medical school mission statements between 2013 and 2021 and correlated changes in mission statements with trends in URM student representation. We performed a web search of 136 medical schools’ mission statements and categorized them based on whether they changed their mission statement to add diversity or equity language. We then obtained demographic data of enrolled students at each school and identified the percentage of students identifying as URM in each academic year. We used mixed-effects regression and pair fixed effects linear regression to examine trends in URM student representation and the association between URM student representation and whether a school added diversity and equity content to its mission statement. Results: We found that URM student representation increased by 0.4% per year at schools that added diversity and equity content to their mission statements. Conclusions: Changing medical schools’ mission statements to reflect values of diversity, equity, and inclusion was associated with an increase of less than a 1% per year in URM representation. More research is needed to explore relationships between URM representation and medical school mission statements.

The Furniture Industry of the Philippines is one of the most labor-intensive and artistic industries in the country which develops the hardworking, creative and enterprising qualities of Filipinos in manufacturing best-quality furniture. With this, the Philippines is dubbed as the “Milan of Asia.” In Pampanga alone, there are several furniture SMEs which manufactures for both local and international clients. Aside from the saw dusts as the by product, scrap foams are also a hurdle for the furniture manufacturers in Pampanga and Central Luzon. Due to the continuous demand of the furniture industries in Pampanga, the study incubated to develop a lowcost semi-automated foam shredder prototypes that will cater the need of furniture industries to crash foams within the customer specification to create a new set of raw materials. The system requirements for the prototypes followed the first utility model that was created. The target of the study is to reduce the production and operating cost of the foam shredder without compromising the capacity, quality and aesthetics of the prototype. The prototype must pass the requirements as follows: (a) safe and efficient, (b) easy to use; (c) reliable and maintainable; (d) yielding capacity of 40 kgs/hr. Ten (10) furniture companies are selected in order to conduct the validation testing of the prototypes developed.

Underrepresented minority student recruitment initiatives from medical school admissions and diversity offices can bring equity for those learners underrepresented in medicine. Measuring growth of the applicant pool helps determine the impact of such initiatives in helping diversify the healthcare workforce.The authors evaluated underrepresented minority applicant pool growth at the Brody School of Medicine to determine whether predominantly White institutions or historically Black colleges and universities have accounted for the most growth in minority applicants in recent years.Outreach outcomes across the state were obtained by comparing applicant and matriculant demographics. Data on all applicants and matriculants were retrieved from the school's institutional records and classified according to student self-identification as underrepresented minority. Using Chi-square tests, authors aimed to determine whether the proportion of minority students increased among applicants and matriculants since 2016, the year of restructuring outreach. In further analysis, the number of graduates from historically Black colleges and universities as compared to minority graduates from predominantly White schools was evaluated.The authors identified 7,848 applicants and 654 matriculants over the evaluation period. The proportion of learners identifying as underrepresented minority increased from 17% before 2016 (622/3,672) to 20% after 2016 (835/4,176; p = 0.001). The proportion of applicants who did not graduate from a historically Black college or university increased slightly after 2016 (89% of underrepresented minority applicants before 2016 vs. 92% of underrepresented minority applicants after 2016), but this increase was not statistically significant (p = 0.097).Applicant growth has been more significant for underrepresented minority applicants from predominantly White institutions. Graduates of targeted historically Black colleges and universities who applied to Brody School of Medicine were better prepared, resulting in increased chances of admission.

The study was undertaken to verify performance of a commercially available water ionizing device that uses carbon nanotube to treat particulates and other pollutants found in drinking water. Two (2) deep well stations belonging to a local water concessionaire known to have quality issues were considered. Water samples were collected and analyzed for physicochemical, bacteriological and organic parameters such as Total Alkalinity, Bicarbonates, Acidity, Free CO2, Chlorine, Total Hardness, Calcium Hardness, Ca, Mg, pH, Residual Chlorine, Turbidity, TDS, color, Fe, Mn, Total coliform, HPC count and Dieldrin. The device’s performance efficiency in treating the pollutants was calculated. The products’ claims were verified thru actual test results. Results indicate that the device is not working as it should. It has very minimal color, Fe and Mn removal – contrary to the product claims and has zero dieldrin treatment capability. On the brighter side, the device reduced total coliform by an average of 59.67% although HPC count spiked by an average of 1,210%. The obtained results will be useful in optioneering for future treatment technologies for the water concessionaire or similar waterworks.

Introduction: Primary care physicians serve on the front lines of care and provide comprehensive care to patients who may have difficulty accessing subspecialists. However, not enough students are entering residency in primary care fields to meet the primary care physician shortage. The authors sought to compare primary care match rates among graduates of medical schools in the state of North Carolina from 2014 to 2018. Methods: The 4 allopathic medical schools in the state of North Carolina were selected for this study: East Carolina University (ECU) Brody School of Medicine, University of North Carolina (UNC) Chapel Hill, Duke School of Medicine, and Wake Forest School of Medicine. Primary care specialties were defined as family medicine, internal medicine, pediatrics, and internal medicine/pediatrics. The proportion of students matching to a residency in any of these fields, and in each specific field, was compared across schools. Results: Over 2014-2018, 214 ECU Brody School of Medicine graduates, 386 UNC graduates, 165 Duke graduates, and 196 Wake Forest graduates matched to a primary care specialty. ECU had the highest proportion of its graduates match in a primary care specialty (53%, compared with 34% to 45% at other schools; P < .001), and was particularly distinguished by having the highest proportions of graduates match to residencies in family medicine (18%) and pediatrics (16%). Conclusion: During the study period of 2014-2018, the ECU Brody School of Medicine matched more medical students into primary care specialties than the other medical schools in the state. This school’s community-driven mission and rural location, among other characteristics facilitating sustained student commitment to primary care careers, can inform the development of new medical schools in the United States to overcome the primary care physician shortage.

The Furniture Industry of the Philippines is one of the most labor-intensive and artistic industries in the country which develops the hardworking, creative and enterprising qualities of Filipinos in manufacturing best-quality furniture. With this, the Philippines is dubbed as the “Milan of Asia.” In Pampanga alone, there are several furniture SMEs which manufactures for both local and international clients. Aside from the saw dusts as the by product, scrap foams are also a hurdle for the furniture manufacturers in Pampanga and Central Luzon. Due to the continuous demand of the furniture industries in Pampanga, the study incubated to develop a lowcost semi-automated foam shredder prototypes that will cater the need of furniture industries to crash foams within the customer specification to create a new set of raw materials. The system requirements for the prototypes followed the first utility model that was created. The target of the study is to reduce the production and operating cost of the foam shredder without compromising the capacity, quality and aesthetics of the prototype. The prototype must pass the requirements as follows: (a) safe and efficient, (b) easy to use; (c) reliable and maintainable; (d) yielding capacity of 40 kgs/hr. Ten (10) furniture companies are selected in order to conduct the validation testing of the prototypes developed.

Erratum to: A&A, 620, A125 (2018), https://doi.org/10.1051/0004-6361/201732442

Author(s): Schlegel, David J; Kollmeier, Juna A; Aldering, Greg; Bailey, Stephen; Baltay, Charles; Bebek, Christopher; BenZvi, Segev; Besuner, Robert; Blanc, Guillermo; Bolton, Adam S; Bouri, Mohamed; Brooks, David; Buckley-Geer, Elizabeth; Cai, Zheng; Crane, Jeffrey; Dey, Arjun; Doel, Peter; Fan, Xiaohui; Ferraro, Simone; Font-Ribera, Andreu; Gutierrez, Gaston; Guy, Julien; Heetderks, Henry; Huterer, Dragan; Infante, Leopoldo; Jelinsky, Patrick; Johns, Matthew; Karagiannis, Dionysios; Kent, Stephen M; Kim, Alex G; Kneib, Jean-Paul; Kronig, Luzius; Konidaris, Nick; Lahav, Ofer; Lampton, Michael L; Lang, Dustin; Leauthaud, Alexie; Liguori, Michele; Linder, Eric V; Magneville, Christophe; Martini, Paul; Mateo, Mario; McDonald, Patrick; Miller, Christopher J; Moustakas, John; Myers, Adam D; Mulchaey, John; Newman, Jeffrey A; Nugent, Peter E; Palanque-Delabrouille, Nathalie; Padmanabhan, Nikhil; Piro, Anthony L; Poppett, Claire; Prochaska, Jason X; Pullen, Anthony R; Rabinowitz, David; Ramirez, Solange; Rix, Hans-Walter; Ross, Ashley J; Samushia, Lado; Schaan, Emmanuel; Schubnell, Michael; Seljak, Uros; Seo, Hee-Jong; Shectman, Stephen A; Silber, Joseph; Simon, Joshua D; Slepian, Zachary; Soares-Santos, Marcelle; Tarle, Greg; Thompson, Ian; Valluri, Monica; Wechsler, Risa H; White, Martin; Wilson, Michael J; Yeche, Christophe; Zaritsky, Dennis | Abstract: MegaMapper is a proposed ground-based experiment to measure Inflation parameters and Dark Energy from galaxy redshifts at 2

Aims. Our aim is to determine the distribution of stellar population parameters (extinction, age, metallicity, and star formation rates) of quiescent galaxies within the rest-frame stellar mass-colour diagrams and UVJ colour-colour diagrams corrected for extinction up to z similar to 1. These novel diagrams reduce the contamination in samples of quiescent galaxies owing to dust-reddened galaxies, and they provide useful constraints on stellar population parameters only using rest-frame colours and /or stellar mass. Methods. We set constraints on the stellar population parameters of quiescent galaxies combining the ALHAMBRA multi-filter photo-spectra with our fitting code for spectral energy distribution, MUlti-Filter FITting (MUFFIT), making use of composite stellar population models based on two independent sets of simple stellar population (SSP) models. The extinction obtained by MUFFIT allowed us to remove dusty star-forming (DSF) galaxies from the sample of red UVJ galaxies. The distributions of stellar population parameters across these rest-frame diagrams are revealed after the dust correction and are fitted by LOESS, a bi-dimensional and locally weighted regression method, to reduce uncertainty effects. Results. Quiescent galaxy samples defined via classical UVJ diagrams are typically contaminated by a similar to 20% fraction of DSF galaxies. A significant part of the galaxies in the green valley are actually obscured star-forming galaxies (similar to 30-65%). Consequently, the transition of galaxies from the blue cloud to the red sequence, and hence the related mechanisms for quenching, seems to be much more efficient and faster than previously reported. The rest-frame stellar mass-colour and UVJ colour-colour diagrams are useful for constraining the age, metallicity, extinction, and star formation rate of quiescent galaxies by only their redshift, rest-frame colours, and /or stellar mass. Dust correction plays an important role in understanding how quiescent galaxies are distributed in these diagrams and is key to performing a pure selection of quiescent galaxies via intrinsic colours.© ESO 2019, The authors are grateful to the referee for their fruitful comments, which contributed to improving the present research. This work has been supported by the Programa Nacional de Astronomia y Astrofisica of the Spanish Ministry of Economy and Competitiveness (MINECO, grants AYA2012-30789 and AYA2015-66211-C2-1-P), by the Ministry of Science and Technology of Taiwan (grant MOST 106-2628-M-001-003-MY3), by the Academia Sinica (grant AS-IA-107-M01), and by the Government of Aragon (Research Group E103). L. A. D. G. acknowledges support from the Caja Rural de Teruel. L. A. D. G. also thanks I. F. for offering the opportunity to develop part of this research at the Mullard Space Science Laboratory (MSSL). We also acknowledge support from the Spanish Ministry for Economy and Competitiveness and FEDER funds through grants AYA2010-15081, AYA2010-15169, AYA2010-22111-C03-01, AYA2010-22111-C03-02, AYA2011-29517-C03-01, AYA2012-39620, AYA2013-40611-P, AYA2013-42227-P, AYA2013-43188-P, AYA2013-48623-C2-1, AYA2013-48623-C2-2, ESP2013-48274, AYA201457490-P, AYA2014-58861-C3-1, AYA2016-76682-C3-1-P, AYA2016-77846-P, AYA2016-81065-C2-1, AYA2016-81065-C2-2; Generalitat Valenciana projects Prometeo 2009/064 and PROMETEOII/2014/060; Junta de Andalucia grants TIC114, JA2828, P10-FQM-6444; and Generalitat de Catalunya project SGR-1398. Throughout this research, we made use of the Matplotlib package (Hunter 2007), a 2D graphics package used for Python that is designed for interactive scripting and quality image generation. This paper is dedicated to Marian Leon Canalejo for being there when L. A. D. G. needed her most and for her patience and continuous encouragement he was finishing his PhD.

Importance There continue to be low numbers of underrepresented minorities, including African Americans, in academic medicine. Historically Black medical colleges and universities are major sources of training for medical school graduates who are African American or who belong to other underrepresented minority groups. Several historically Black medical schools were closed during the period surrounding the 1910 Flexner report. The implications of these school closures with regard to the number of African American medical school graduates have not been fully examined. Objective To examine the consequences associated with the closure of historically Black medical schools for the number of African American medical school graduates. Design, Setting, and Participants This observational economic evaluation used steady expansion and rapid expansion models to estimate the consequences associated with the closure of historically Black medical schools for the number of African American medical school graduates. The numbers of graduates from 13 historically Black medical schools that are now closed were obtained through historical records. Data on historically Black medical schools that are currently open were obtained from school-specific reports and reports published by the Association of American Medical Colleges. The study focused on projected estimates of outcomes from the hypothetical continued operation and expansion of 5 closed historically Black medical schools that were included in the Flexner report: Flint Medical College of New Orleans University, Knoxville Medical College, Leonard Medical School of Shaw University, Louisville National Medical College, and the University of West Tennessee College of Medicine and Surgery–Memphis. Main Outcomes and Measures The main outcome was the estimate of the number of African American students who would have graduated from historically Black medical schools that were closed during the period surrounding the 1910 Flexner report. Results Among the 5 historically Black medical schools that were closed, the estimated mean number of graduates per year was 5.27 students at Flint Medical College, 2.60 students at Knoxville Medical College, 11.06 students at Leonard Medical School, 4.17 students at Louisville National Medical College, and 6.74 students at the University of West Tennessee. If the 5 closed historically Black medical schools had remained open, the steady expansion and rapid expansion models indicated that these schools might have collectively provided training to an additional 27 773 graduates and 35 315 graduates, respectively, between their year of closure and 2019. In the analysis of Leonard Medical School and the University of West Tennessee only, the steady expansion and rapid expansion models indicated that these 2 schools would have provided training to an additional 10 587 graduates and 13 403 graduates, respectively, between their year of closure and 2019. An extrapolation based on the racial and ethnic self-identification of current graduates of historically Black medical schools indicated that if these closed schools had remained open, the number of graduating African American physicians might have increased by 355 individuals (29%) in 2019 alone. Conclusions and Relevance To increase the number of African American medical school graduates, consideration should be given to creating medical education programs at historically Black colleges and universities. Such programs may start with small enrollment but could have positive consequences for the diversity of the physician workforce.

Las Campanas Observatory (LCO) of the Carnegie Institution of Science has been operating in Chile for about 50 years, currently operating four main telescopes. Carnegie operates the two 6.5 meter Magellan telescopes on behalf of a partnership that includes a consortium of universities. The Magellan Telescopes were commissioned in 2000 and 2002 and offer the consortium users a suite of twelve instruments. In this paper we will first provide a brief description of the science, technical and administrative structure of the observatory. We will then present an updated review of the Magellan telescopes operations and maintenance. Details on status and performances of the instruments will be given. We will finally cover the operations of the duPont 2.5 meter and Swope 1 meter telescopes including the current and future collaboration with the two hemisphere surveys SDSS-IV and SDSS-V.

Background Since 2009, the Surgical Block Pharmacy has been involved in the management of medical devices (MD) via centralisation, the use rationalisation and the production of procedural kits (standardised MD sets including sutures, syringes and scalpels, associated with one or more surgical procedure). Since June 2016, the production of kits has been implemented with eye surgery, first cataract surgery and intravitreal injections, and, since January 2017, with all types of eye surgery. Kit composition is periodically reviewed by the pharmacist through the analysis of unused MD returned to the pharmacy. Purpose To optimise kit contents, to improve logistics and to streamline daily delivery processes. Material and methods We analysed unused MD returned to the pharmacy from the ophthalmic operating room for every kit in the first 4 months of 2017. MD returned to the pharmacy were analysed via a query of the logistic software. Our focus was concentrated on the most critical kits, identified by unused MD returned ≥50%. Once the critical MD was identified, we estimated whether the quantity was to be reduced or the MD should be removed. Subsequently, the change was proposed to the operating room staff, to be accepted and approved by the head physician. At the same time, kit content was re-evaluated, if necessary with the addition of other MD. Results Twenty-five different types of kits were prepared for eye surgery. Fifteen kits had unused MD returned to the Pharmacy ≥50% and all were analysed. Contents of 11 kits (73%) were revised: in particular, 30 MD were removed (26% of unused MD returned and analysed) and the amount of nine MD was reduced (8%). For MD removed from kits, a storage space was provided in the operating room cabinet. We replaced two MD and added one MD. In addition, new kits will be created for specialised surgery. Conclusion ?Analysis of unused MD returned is useful for identification of critical issues and for standardisation-optimisation (the most difficult requirement), significantly reducing MD amount returned to the pharmacy, which negatively affects working time. We cleared human resources’ activity that can be used to implement the Surgical Block Pharmacy activity and increase kthe production of kits. In this way operating rooms’ needs can be met, confirming the efficiency of our system. No conflict of interest

Most sub-mm emission line studies of galaxies to date have targeted sources with known redshifts where the frequencies of the lines are well constrained. Recent blind line scans circumvent the spectroscopic redshift requirement, which could represent a selection bias. Our aim is to detect emission lines present in continuum oriented observations. The detection of such lines provides spectroscopic redshift and yields properties of the galaxies. We perform a search for emission lines in the ALMA observations of five Frontier Fields clusters and assess the reliability of our detection by associating line candidates with detected galaxies in deep near-infrared imaging. We find 26 significant emission lines candidates, with observed line fluxes between 0.2-4.6 Jy km s$^{-1}$ and velocity dispersions (FWHM) of 25-600 km s$^{-1}$. Nine of these candidates lie nearby to near-infrared sources, boosting their reliability; in six cases the observed line frequency and strength are consistent with expectations given the photometric redshift and properties of the galaxy counterparts. We present redshift identifications, magnifications and molecular gas estimates for the galaxies with identified lines. We show that two of these candidates likely originate from starburst galaxies, one of which is a jellyfish galaxy, while another two are consistent with being main sequence galaxies based in their depletion times. This work highlights the degree to which serendipitous emission lines can be discovered in large mosaic continuum observations when deep ancillary data are available. The low number of high-significance line detections, however, confirms that such surveys are not as optimal as blind line scans. We stress that Monte Carlo simulations should be used to assess the line detections significances, since using the negative noise suffers from stochasticity and incurs larger uncertainties., new version accepted for publication in A&A

Background Vinorelbine is an antineoplastic drug belonging to the family of vinca alkaloids. Initially it was marketed for intravenous use and then it was made available as an oral formulation, to improve access and adherence to treatment, and to reduce procedures and costs of hospitalisation. Metronomic chemotherapy, compared with traditional schedules, is based on more frequent administration of low dose drugs, with the aim of preventing tumour angiogenesis. Purpose To investigate the use of metronomic chemotherapy with oral vinorelbine in our hospital; an epidemiological analysis and an economic evaluation were performed. Material and methods We examined prescriptions of vinorelbine and discharge sheets of oncology outpatient visits in 2015. We analysed the costs of the treatment schedules. Results 31 patients were treated with oral vinorelbine, 18 (58%) with the metronomic schedule (off-label) for metastatic breast cancer (15) and metastatic non-small cell lung cancer (3). Mean age was 69 years (range 43–85); almost all patients were women (30/31) and with a good performance status at the beginning of treatment (12 PS 0, 5 PS 1, 1 missing). 15 patients had progressive disease and 3 were partially responding. Mean length of this type of chemotherapy was 3 months, with good compliance and tolerance. In 2015, consumption of oral vinorelbine increased (+380% vs 2014), while consumption of the injectable formulation decreased (−44%). Direct costs of the oral formulation of vinorelbine (both metronomic and traditional schedule) were higher than the direct costs of the intravenous formulation; for the latter, we must however add the costs of hospitalisation and hospital staff for preparation and administration of the drug. Conclusion We can explain the rise in consumption of the oral formulation with the use of metronomic therapy and with an increase in the number of patients. The metronomic schedule was used as maintenance therapy and the preferred candidate is the elderly patient, a unique setting where the risk/benefit ratio of any antineoplastic treatment should be carefully evaluated. Metronomic chemotherapy with oral vinorelbine is an appealing option for patients who express their preference for oral chemotherapy. No conflict of interest

We investigate the effect of political connections in Italy, for each level of government, on the credit markets and we find robust evidence that politically connected firms benefit from lower interest rates when the political link is at a local level. Our results show that this preferential treatment is stronger when connected firms borrow from banks with politicians on their boards and when the degree of autonomy granted to local loan officers is higher. The latter result provides a novel addition to the literature on the effects of the delegation of lending decisions within the bank. We also show that the effect is stronger in geographical areas where the incidence of corruption is higher. Overall, our results show that on aggregate the impact of political connections on interest rates is limited but it may rise significantly in specific (local) situations due to a combination of factors such as the delegation of lending decisions, a weaker rule of law and some governance characteristics of banks.

We present the largest-ever sample of 79 Ly$\alpha$ emitters (LAEs) at $z\sim$ 7.0 selected in the COSMOS and CDFS fields of the LAGER project (the Lyman Alpha Galaxies in the Epoch of Reionization). Our newly amassed ultradeep narrowband exposure and deeper/wider broadband images have more than doubled the number of LAEs in COSMOS, and we have selected 30 LAEs in the second field CDFS. We detect two large-scale LAE-overdense regions in the COSMOS that are likely protoclusters at the highest redshift to date. We perform injection and recovery simulations to derive the sample incompleteness. We show significant incompleteness comes from blending with foreground sources, which however has not been corrected in LAE luminosity functions in {the} literature. The bright end bump in the Ly$\alpha$ luminosity function in COSMOS is confirmed with 6 (2 newly selected) luminous LAEs (L$_{Ly\alpha}$ $>$ 10$^{43.3}$ erg s$^{-1}$). Interestingly, the bump is absent in CDFS, in which only one luminous LAE is detected. Meanwhile, the faint end luminosity functions from the two fields well agree with each other. The 6 luminous LAEs in COSMOS coincide with 2 LAE-overdense regions, while such regions are not seen in CDFS. The bright-end luminosity function bump could be attributed to ionized bubbles in a patchy reionization. It appears associated with cosmic overdensities, thus supports an inside-out reionization topology at $z$ $\sim$ 7.0, i.e., the high density peaks were ionized earlier compared to the voids. An average neutral hydrogen fraction of $x_{HI}$ $\sim$ 0.2 -- 0.4 is derived at $z\sim$ 7.0 based on the cosmic evolution of the Ly$\alpha$ luminosity function., Comment: 23 pages, 11 figures, 2 tables, accepted for publication in ApJ

We present the results of a numerical study based on the analysis of the MUSIC-2 simulations, aimed at estimating the expected concentration-mass relation for the CLASH cluster sample. We study nearly 1400 halos simulated at high spatial and mass resolution, which were projected along many lines-of-sight each. We study the shape of both their density and surface-density profiles and fit them with a variety of radial functions, including the Navarro-Frenk-White, the generalised Navarro-Frenk-White, and the Einasto density profiles. We derive concentrations and masses from these fits and investigate their distributions as a function of redshift and halo relaxation. We use the X-ray image simulator X-MAS to produce simulated Chandra observations of the halos and we use them to identify objects resembling the X-ray morphologies and masses of the clusters in the CLASH X-ray selected sample. We also derive a concentration-mass relation for strong-lensing clusters. We find that the sample of simulated halos which resemble the X-ray morphology of the CLASH clusters is composed mainly by relaxed halos, but it also contains a significant fraction of un-relaxed systems. For such a sample we measure an average 2D concentration which is ~11% higher than found for the full sample of simulated halos. After accounting for projection and selection effects, the average NFW concentrations of CLASH clusters are expected to be intermediate between those predicted in 3D for relaxed and super-relaxed halos. Matching the simulations to the individual CLASH clusters on the basis of the X-ray morphology, we expect that the NFW concentrations recovered from the lensing analysis of the CLASH clusters are in the range [3-6], with an average value of 3.87 and a standard deviation of 0.61. Simulated halos with X-ray morphologies similar to those of the CLASH clusters are affected by a modest orientation bias., Comment: 21 pages, 16 figures, 3 tables, submitted to ApJ

We present an analysis of a deep (1$\sigma$=13 $\mu$Jy) cosmological 1.2-mm continuum map based on ASPECS, the ALMA Spectroscopic Survey in the Hubble Ultra Deep Field. In the 1 arcmin$^2$ covered by ASPECS we detect nine sources at $>3.5\sigma$ significance at 1.2-mm. Our ALMA--selected sample has a median redshift of $z=1.6\pm0.4$, with only one galaxy detected at z$>$2 within the survey area. This value is significantly lower than that found in millimeter samples selected at a higher flux density cut-off and similar frequencies. Most galaxies have specific star formation rates similar to that of main sequence galaxies at the same epoch, and we find median values of stellar mass and star formation rates of $4.0\times10^{10}\ M_\odot$ and $\sim40~M_\odot$ yr$^{-1}$, respectively. Using the dust emission as a tracer for the ISM mass, we derive depletion times that are typically longer than 300 Myr, and we find molecular gas fractions ranging from $\sim$0.1 to 1.0. As noted by previous studies, these values are lower than using CO--based ISM estimates by a factor $\sim$2. The 1\,mm number counts (corrected for fidelity and completeness) are in agreement with previous studies that were typically restricted to brighter sources. With our individual detections only, we recover $55\pm4\%$ of the extragalactic background light (EBL) at 1.2 mm measured by the Planck satellite, and we recover $80\pm7\%$ of this EBL if we include the bright end of the number counts and additional detections from stacking. The stacked contribution is dominated by galaxies at $z\sim1-2$, with stellar masses of (1-3)$\times$10$^{10}$ M$_\odot$. For the first time, we are able to characterize the population of galaxies that dominate the EBL at 1.2 mm., Comment: Accepted for publication on the Astrophysical Journal

Biological motors generally fall into two categories: (1) those that convert chemical into mechanical energy via hydrolysis of a nucleoside triphosphate, usually adenosine triphosphate, regarded as life's chemical currency of energy and (2) membrane bound motors driven directly by an ion gradient and/or membrane potential. Here we argue that electrostatic interactions play a vital role for both types of motors and, therefore, the tools of physics can greatly contribute to understanding biological motors.

We present MUFFIT, a new generic code optimized to retrieve the main stellar population parameters of galaxies in photometric multi-filter surveys, and we check its reliability and feasibility with real galaxy data from the ALHAMBRA survey. Making use of an error-weighted $\chi^2$-test, we compare the multi-filter fluxes of galaxies with the synthetic photometry of mixtures of two single stellar populations at different redshifts and extinctions, to provide through a Monte Carlo method the most likely range of stellar population parameters (mainly ages and metallicities), extinctions, redshifts, and stellar masses. To improve the diagnostic reliability, MUFFIT identifies and removes from the analysis those bands that are significantly affected by emission lines. We highlight that the retrieved age-metallicity locus for a sample of $z \le 0.22$ early-type galaxies in ALHAMBRA at different stellar mass bins are in very good agreement with the ones from SDSS spectroscopic diagnostics. Moreover, a one-to-one comparison between the redshifts, ages, metallicities, and stellar masses derived spectroscopically for SDSS and by MUFFIT for ALHAMBRA reveals good qualitative agreements in all the parameters. In addition, and using as input the results from photometric-redshift codes, MUFFIT improves the photometric-redshift accuracy by $\sim 10$-$20\%$, and it also detects nebular emissions in galaxies, providing physical information about their strengths. Our results show the potential of multi-filter galaxy data to conduct reliable stellar population studies with the appropiate analysis techniques, as MUFFIT., Comment: 31 pages, 18 figures, accepted for publication in A&A

[Aims]: Our goal is to develop and test a novel methodology to compute accurate close-pair fractions with photometric redshifts. [Methods]: We improved the currently used methodologies to estimate the merger fraction fm from photometric redshifts by (i) using the full probability distribution functions (PDFs) of the sources in redshift space; (ii) including the variation in the luminosity of the sources with z in both the sample selection and the luminosity ratio constrain; and (iii) splitting individual PDFs into red and blue spectral templates to reliably work with colour selections.We tested the performance of our new methodology with the PDFs provided by the ALHAMBRA photometric survey. [Results]: The merger fractions and rates from the ALHAMBRA survey agree excellently well with those from spectroscopic work for both the general population and red and blue galaxies. With the merger rate of bright (MB ≤ -20 - 1:1z) galaxies evolving as (1 + z)n, the power-law index n is higher for blue galaxies (n = 2:7 0:5) than for red galaxies (n = 1:3 0:4), confirming previous results. Integrating the merger rate over cosmic time, we find that the average number of mergers per galaxy since z = 1 is Nm red = 0:57 0:05 for red galaxies and Nm blue = 0:26 0:02 for blue galaxies. [Conclusions]: Our new methodology statistically exploits all the available information provided by photometric redshift codes and yields accurate measurements of the merger fraction by close pairs from using photometric redshifts alone. Current and future photometric surveys will benefit from this new methodology., This work has been mainly funded by the FITE (Fondos de Inversiones de Teruel) and the projects AYA2012-30789, AYA2006-14056, and CSD2007-00060. We also acknowledge financial support from the Spanish Government grants AYA2010-15169, AYA2010-22111-C03-01, AYA2010-22111-C03-02, and AYA2013-48623-C2-2, from the Aragón Government through the Research Group E103, from the Junta de Andalucía through TIC-114 and the Excellence Project P08-TIC-03531, and from the Generalitat Valenciana through the projects Prometeo/2009/064 and PrometeoII/2014/060. A.J.C. is Ramón y Cajal fellow of the Spanish government. M.P. acknowledges the financial support from JAE-Doc program of the Spanish National Research Council (CSIC), co-funded by the European Social Fund.

We consistently analyse for the first time the impact of survey depth and spatial resolution on the most used morphological parameters for classifying galaxies through non-parametric methods: Abraham and Conselice-Bershady concentration indices, Gini, M20moment of light, asymmetry, and smoothness. Three different non-local data sets are used, Advanced Large Homogeneous Area Medium Band Redshift Astronomical (ALHAMBRA) and Subaru/XMMNewton Deep Survey (SXDS, examples of deep ground-based surveys), and Cosmos Evolution Survey (COSMOS, deep space-based survey). We used a sample of 3000 local, visually classified galaxies, measuring their morphological parameters at their real redshifts (z ~ 0). Then we simulated them to match the redshift and magnitude distributions of galaxies in the non-local surveys. The comparisons of the two sets allow us to put constraints on the use of each parameter for morphological classification and evaluate the effectiveness of the commonly used morphological diagnostic diagrams. All analysed parameters suffer from biases related to spatial resolution and depth, the impact of the former being much stronger. When including asymmetry and smoothness in classification diagrams, the noise effects must be taken into account carefully, especially for ground-based surveys. M20 is significantly affected, changing both the shape and range of its distribution at all brightness levels. We suggest that diagnostic diagrams based on 2-3 parameters should be avoided when classifying galaxies in ground-based surveys, independently of their brightness; for COSMOS they should be avoided for galaxies fainter than F814 = 23.0. These results can be applied directly to surveys similar to ALHAMBRA, SXDS and COSMOS, and also can serve as an upper/lower limit for shallower/deeper ones., MP acknowledge financial support from JAE-Doc programme of the Spanish National Research Council (CSIC), co-funded by the European Social Fund. This research was supported by the Junta de Andalucia through project TIC114, and the Spanish Ministry of Economy and Competitiveness (MINECO) through projects AYA2010-15169, AYA2013-42227-P, and AYA2013-43188-P.

Various formation channels for the puzzling ultra-compact dwarf galaxies (UCDs) have been proposed in the last few years. To better judge on some of the competing scenarios, we present spectroscopic [Fe/H] estimates for a sample of 26 compact objects in the central region of the Fornax cluster, covering the magnitude range of UCDs and bright globular clusters. We find a break in the metallicity distribution of compact objects at M_V ~ -11 mag (~3*10^6 M_sun): for M_V -11 mag. This metallicity break is accompanied by a change in the size-luminosity relation for compact objects, as deduced from HST-imaging: for M_V -11 mag, r_h is almost luminosity-independent. We therefore assume a limiting absolute magnitude of M_V=-11 mag between UCDs and globular clusters. The mean metallicity of five Fornax dE,N nuclei included in our study is about 0.8 dex lower than that of the UCDs, at 4.5 sigma significance. Because of this large metallicity discrepancy we disfavor the hypothesis that most of the Fornax UCDs are the remnant nuclei of tidally stripped dE,Ns. Our metallicity estimates for UCDs are closer to but slightly below those derived for young massive clusters (YMCs) of comparable masses. We therefore favor a scenario where most UCDs in Fornax are successors of merged YMCs produced in the course of violent galaxy-galaxy mergers. It is noted that in contrast to that, the properties of Virgo UCDs are more consistent with the stripping scenario, suggesting that different UCD formation channels may dominate in either cluster.

The color-magnitude relation has been determined for the RDCS J0910+5422 cluster of galaxies at redshift z = 1.106. Cluster members were selected from HST ACS images, combined with ground--based near--IR imaging and optical spectroscopy. The observed early--type color--magnitude relation (CMR) in (i_775 -z_850) versus z_850 shows intrinsic scatters in color of 0.042 +/- 0.010 mag and 0.044 +/- 0.020 mag for ellipticals and S0s, respectively. From the scatter about the CMR, a mean luminosity--weighted age t > 3.3 Gyr (z > 3) is derived for the elliptical galaxies. Strikingly, the S0 galaxies in RDCS J0910+5422 are systematically bluer in (i_775 - z_850) by 0.07 +/- 0.02 mag, with respect to the ellipticals. The ellipticity distribution as a function of color indicates that the face-on S0s in this particular cluster have likely been classified as elliptical. Thus, if anything, the offset in color between the elliptical and S0 populations may be even more significant. The color offset between S0 and E corresponds to an age difference of ~1 Gyr, for a single-burst solar metallicity model. A solar metallicity model with an exponential decay in star formation will reproduce the offset for an age of 3.5 Gyr, i.e. the S0s have evolved gradually from star forming progenitors. The early--type population in this cluster appears to be still forming. The blue early-type disk galaxies in RDCS J0910+5422 likely represent the direct progenitors of the more evolved S0s that follow the same red sequence as ellipticals in other clusters. Thirteen red galaxy pairs are observed and the galaxies associated in pairs constitute ~40% of the CMR galaxies in this cluster., ApJ, in press

We present deep optical imaging of the z=4.1 radio galaxy TN J1338--1942 obtained using the ACS on-board HST. The radio galaxy is known to reside within a large galaxy overdensity (both in physical extent and density contrast). There is good evidence that this `protocluster' region is the progenitor of a present-day rich galaxy cluster. TN J1338 is the dominant galaxy in the protocluster, in terms of size and luminosity and therefore seems destined to evolve into the brightest cluster galaxy. The high spatial-resolution ACS images reveal several kpc-scale features within and around the radio galaxy. The continuum light is aligned with the radio axis and is resolved into two clumps in the i-band and z-band bands. These components have luminosities ~10^9 L_sun and sizes of a few kpc. The estimated star-formation rate for the whole radio galaxy is ~200 M_sun/yr. A simple model in which the jet has triggered star-formation in these continuum knots is consistent with the available data. An unusual feature is seen in Lyman-alpha emission. A wedge-shaped extension emanates from the radio galaxy perpendicularly to the radio axis. This `wedge' naturally connects to the surrounding, asymmetric, large-scale (~100 kpc) Lyman-alpha halo. We posit that the wedge is a starburst-driven superwind, associated with the first major epoch of formation of the brightest cluster galaxy. The shock and wedge are examples of feedback processes due to both AGN and star-formation in the earliest stages of massive galaxy formation., Comment: 41 pages, 12 figures. Accepted to ApJ

We measure the luminosity function of morphologically selected E/S0 galaxies from $z=0.5$ to $z=1.0$ using deep high resolution Advanced Camera for Surveys imaging data. Our analysis covers an area of $48\Box\arcmin$ (8$\times$ the area of the HDF-N) and extends 2 magnitudes deeper ($I\sim24$ mag) than was possible in the Deep Groth Strip Survey (DGSS). At $0.51.7$, E/S0 galaxies at brighter luminosities ($M_B

(Abridged) We study the internal color properties of a morphologically selected sample of spheroidal galaxies taken from HST/ACS ERO program of UGC 10214 (``The Tadpole''). By taking advantage of the unprecedented high resolution of the ACS in this very deep dataset we are able to characterize spheroids at sub-arcseconds scales. Using the V_606W and I_814W bands, we construct V-I color maps and extract color gradients for a sample of spheroids at I_814W < 24 mag. We investigate the existence of a population of morphologically classified spheroids which show extreme variation in their internal color properties similar to the ones reported in the HDFs. These are displayed as blue cores and inverse color gradients with respect to those accounted from metallicity variations. Following the same analysis we find a similar fraction of early-type systems (~30%-40%) that show non-homologous internal colors, suggestive of recent star formation activity. We present two statistics to quantify the internal color variation in galaxies and for tracing blue cores, from which we estimate the fraction of non-homogeneous to homogeneous internal colors as a function of redshift up to z

We present the analysis of the faint galaxy population in the Advanced Camera for Surveys (ACS) Early Release Observation fields VV 29 (UGC 10214) and NGC 4676. Here we attempt to thoroughly consider all aspects relevant for faint galaxy counting and photometry, developing methods which are based on public software and that are easily reproducible by other astronomers. Using simulations we determine the best SExtractor parameters for the detection of faint galaxies in deep HST observations, paying special attention to the issue of deblending, which significantly affects the normalization and shape of the number count distribution. We confirm, as claimed by Bernstein, Freedman and Madore (2002), that Kron-like magnitudes, such as the ones generated by SExtractor, can miss more than half of the light of faint galaxies, what dramatically affects the slope of the number counts. We present catalogs for the VV 29 and NGC 4676 fields with photometry in the g,V and I bands. We also show that combining the bayesian software BPZ with superb ACS data and new spectral templates enables us to estimate reliable photometric redshifts for a significant fraction of galaxies with as few as three filters. After correcting for selection effects, we measure slopes of 0.32+- 0.01 for 22 25.5 can be well approximated in all our filters by a passive luminosity evolution model based on the COMBO-17 luminosity function (\alpha=-1.5), with a strong merging rate following the prescription of Glazebrook et al. (1994), \phi^*\propto (1+Qz), with Q=4.

Using an i-z dropout criterion, we determine the space density of z~6 galaxies from two deep ACS GTO fields with deep optical-IR imaging. A total of 23 objects are found over 46 arcmin^2, or ~0.5 objects/arcmin^2 down to z~27.3 (6 sigma; all AB mag) (including one probable z~6 AGN). Combining deep ISAAC data for our RDCS1252-2927 field (J~25.7 and Ks~25.0 (5 sigma)) and NICMOS data for the HDF North (JH~27.3 (5 sigma)), we verify that these dropouts have flat spectral slopes. i-dropouts in our sample range in luminosity from ~1.5 L* (z~25.6) to ~0.3 L* (z~27.3) with the exception of one very bright candidate at z~24.2. The half-light radii vary from 0.09" to 0.29", or 0.5 kpc to 1.7 kpc. We derive the z~6 rest-frame UV luminosity density using three different procedures, each utilizing simulations based on a CDF South V dropout sample. First, we compare our findings with a no-evolution projection of this V-dropout sample. We find 23+/-25% more i-dropouts than we predict. Adopting previous results to z~5, this works out to a 20+/-29% drop in the luminosity density from z~3 to z~6. Second, we use these same V-dropout simulations to derive a selection function for our i-dropout sample and compute the UV-luminosity density (7.2+/-2.5 x 10^25 ergs/s/Hz/Mpc^3 down to z~27). We find a 39+/-21% drop over the same redshift range. This is our preferred value and suggests a star formation rate of 0.0090+/-0.0031 M_sol/yr/Mpc^3 to z~27, or ~0.036+/- 0.012 M_sol/yr/Mpc^3 extrapolating the LF to the faint limit. Third, we follow a very similar procedure, but assume no incompleteness, finding a luminosity density which is ~2-3X lower. This final estimate constitutes a lower limit. All three estimates are within the canonical range of luminosity densities necessary for reionization of the universe at this epoch. (abridged)

Multicolor coronagraphic images of the circumstellar disk around HD141569A have been obtained with the Hubble Space Telescope (HST) Advanced Camera for Surveys. B, V, and I images show that the disk's previously-described multiple-ring structure is actually a continuous distribution of dust with a tightly-wound spiral structure. Two, more open spiral arms extend from the disk, one of which appears to reach the nearby binary star HD141569BC. Diffuse dust is seen up to 1200AU from HD141569A. Although planets may exist in the inner region of the disk, tidal interaction with HD141569BC seems more likely to be the cause of these phenomena. The disk appears redder than the star (B-V = 0.21 and V-I = 0.25), and its color is spatially uniform. A scattering asymmetry factor of g = 0.25-0.35 is derived. The azimuthal density distribution is asymmetric, varying by a factor of ~3 at some radii.

We test the hypothesis whether high redshift QSOs would preferentially appear in small groups or pairs, and if they are associated with massive, young clusters. We carried out a photometric search for \Ly emitters on scales $\lesssim 10 h^{-1}$ Mpc, in the fields of a sample of 47 $z\approx3$ known QSOs. Wide and narrow band filter color-magnitude diagrams were generated for each of the $6'.6\times6'.6$ fields. A total of 13 non resolved objects with a significant color excess were detected as QSO candidates at a redshift similar to that of the target. All the candidates are significantly fainter than the reference QSOs, with only 2 of them within 2 magnitudes of the central object. Follow-up spectroscopic observations have shown that 5, i.e., about 40% of the candidates, are QSOs at the same redshift of the target; 4 are QSOs at different z (two of them probably being a lensed pair at z = 1.47); 2 candidates are unresolved HII galaxies at z$\sim$0.3; one unclassified and one candidate turned out to be a CCD flaw. These data indicate that at least 10% of the QSOs at z$\sim$3 do have companions. We have also detected a number of resolved, rather bright \Ly Emitter Candidates. Most probably a large fraction of them might be bright galaxies with [OII] emission, at z$\approx$ 0.3. The fainter population of our candidates corresponds to the current expectations. Thus, there are no strong indication for the existence of an overdensity of \Ly galaxies brighter than m $\approx$ 25 around QSOs at $z\approx$ 3.

A line-integral representation is presented for a linearly polarized Kirchhoff-type aperture radiation from a parabolic reflector antenna. The main purpose of this result is concerned with the acceleration of the numerical integration for calculating the near field of large reflector antennas. The formulation, which is rigorous for a uniform aperture field, is based on the application of the equivalence principle to a projecting surface, which allows the analytical evaluation in a closed form of a twofold surface integral which defines the radiated field at any space point; the extension to a slowly varying primary feed pattern is based on an asymptotic approximation, which is proved to be accurate in the proximity of the aperture to -30 dB of amplitude edge illumination. The present formulation is well suited to be improved by fringe diffraction contributions in the framework of edge-wave theories such as the physical theory of diffraction (PTD) and the incremental theory of diffraction (ITD).

Maternal occupational pesticide exposure during pregnancy and/or paternal occupational pesticide exposure around conception have been suggested to increase risk of leukemia in the offspring. With a view to providing insight in this area we pooled individual level data from 13 case-control studies participating in the Childhood Leukemia International Consortium (CLIC). Occupational data were harmonized to a compatible format. Pooled individual analyses were undertaken using unconditional logistic regression. Using exposure data from mothers of 8,236 cases, and 14,850 controls, and from fathers of 8,169 cases and 14,201 controls the odds ratio (OR) for maternal exposure during pregnancy and the risk of acute lymphoblastic leukemia (ALL) was 1.01 [95% confidence interval (CI) 0.78, 1.30] and for paternal exposure around conception 1.20 (95% 1.06, 1.38). For acute myeloid leukemia (AML), the OR for maternal exposure during pregnancy was 1.94 (CI 1.19, 3.18) and for paternal exposure around conception 0.91 (CI 0.66, 1.24.) based on data from 1,329 case and 12,141 control mothers, and 1,231 case and 11,383 control fathers. Our finding of a significantly increased risk of AML in the offspring with maternal exposure to pesticides during pregnancy is consistent with previous reports. We also found a slight increase in risk of ALL with paternal exposure around conception which appeared to be more evident in children diagnosed at the age of 5 years or more and those with T cell ALL which raises interesting questions on possible mechanisms. What's new? When parents are exposed to pesticides during pregnancy or conception, does this increase the risk of leukemia in their child? The answer is yes. Using pooled individual level occupational pesticide exposure data from 13 case-control studies the authors found an increased risk of acute myeloid leukemia with maternal exposure during pregnancy and a slightly increased risk of acute lymphoblastic leukemia with paternal exposure around conception. The next step is to get more detailed information on pesticide types and protective measures during application before conclusive recommendations for pesticide use in the workforce can be made. © 2014 UICC.

Growing observational evidence now indicates that nebular line emission has a significant impact on the rest-frame optical fluxes of z~5-7 galaxies observed with Spitzer. This line emission makes z~5-7 galaxies appear more massive, with lower specific star formation rates. However, corrections for this line emission have been very difficult to perform reliably due to huge uncertainties on the overall strength of such emission at z>~5.5. Here, we present the most direct observational evidence yet for ubiquitous high-EW [OIII]+Hbeta line emission in Lyman-break galaxies at z~7, while also presenting a strategy for an improved measurement of the sSFR at z~7. We accomplish this through the selection of bright galaxies in the narrow redshift window z~6.6-7.0 where the IRAC 4.5 micron flux provides a clean measurement of the stellar continuum light. Observed 4.5 micron fluxes in this window contrast with the 3.6 micron fluxes which are contaminated by the prominent [OIII]+Hbeta lines. To ensure a high S/N for our IRAC flux measurements, we consider only the brightest (H_{160}~4 Gyr^-1 on the specific star formation rates based on the mean SED for our seven-source sample. (abridged), 9 pages, 6 figures, 1 table, submitted to the Astrophysical Journal