1. Enamel Based Composite Layers Deposited on Titanium Substrate with Antifungal Activity
- Author
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L. Iconaru, S., M. Prodan, A., S. Turculet, C., Beuran, M., V. Ghita, R., Costescu, A., Groza, A., C. Chifiriuc, M., Chapon, P., Gaiaschi, S., Hristu, R., A. Stanciu, G., Trusca, R., Ganciu, M., M. Raita, S., Vineticu, N., and S. Ciobanu, C.
- Abstract
The goal of this paper was to investigate the antifungal activity of Enamel layers deposited on titanium substrate (Ti-Enamel) and Enamel layers deposited on titanium substrate previously coated with a vinyl polydimethylsiloxane layer (Ti-PDMS-Enamel). The physicochemical properties were also investigated. The Candida albicans biofilm development on the obtained layers was examined after 24 h, 48 h, and 72 h by confocal laser scanning microscopy (CLSM) and scanning electron microscopy (SEM) after ethidium bromide staining. A significant inhibition of the fungal adherence and biofilm development was observed on Ti-Enamel layers. The antifungal results demonstrated that the use of new Ti-Enamel composite layers could represent a promising perspective for the prevention of fungal biofilms associated implant infections.
- Published
- 2016
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