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8. ON THE ADRENERGIC BETA RECEPTORS OF THE NICTITATING MEMBRANE

Author

L, GYOERGY, J, MOLNAR, and M, DODA

Subjects
Pharmacology, Sympathetic Nervous System, Epinephrine, Sensory Receptor Cells, Research, Amphetamines, Isoproterenol, Neurophysiology, Amphetamine, Receptors, Adrenergic, beta, Cats, Ergotamine, Animals, Tolazoline, Nictitating Membrane
Published
1965

9. COMPARATIVE PHARMACOLOGICAL STUDIES OF GANGLIONIC STIMULANTS: DIMETHYLPHENYLPIPERAZINIUM BROMIDE (DMPP), TETRAMETHYLAMMONIUM BROMIDE (TMA) AND GANGLIONIC STIMULANTS OF THE TROPINE TYPE. I

Author

J, MOLNAR, L, GYOERGY, M, DODA, and K, NADOR

Subjects
Atropine, Bromides, Guinea Pigs, Blood Pressure, Hexamethonium Compounds, Piperazines, Dogs, Cocaine, Ammonium Compounds, Animals, Nictitating Membrane, Sympathomimetics, Pentobarbital, Pharmacology, Research, Respiration, Lidocaine, Blood Pressure Determination, Ganglionic Stimulants, Quaternary Ammonium Compounds, Chloralose, Cats, Sympatholytics, Rabbits, Dimethylphenylpiperazinium Iodide, Procaine, Tropanes
Published
1964

13. COMPARATIVE PHARMACOLOGICAL STUDIES OF GANGLIONIC STIMULANTS: DIMETHYLPHENYLPIPERAZINIUM BROMIDE (DMPP), TETRAMETHYLAMMONIUM BROMIDE (TMA) AND GANGLIONIC STIMULANTS OF THE TROPINE TYPE. I.

Author

MOLNAR J, GYOERGY L, DODA M, and NADOR K

Subjects
Animals, Cats, Dogs, Guinea Pigs, Rabbits, Ammonium Compounds, Atropine, Blood Pressure, Blood Pressure Determination, Bromides, Chloralose, Cocaine, Dimethylphenylpiperazinium Iodide, Ganglionic Stimulants, Hexamethonium Compounds, Lidocaine, Nictitating Membrane, Pentobarbital, Pharmacology, Piperazines, Procaine, Quaternary Ammonium Compounds, Research, Respiration, Sympatholytics, Sympathomimetics, Tropanes
Published
1964

15. ON THE ADRENERGIC BETA RECEPTORS OF THE NICTITATING MEMBRANE.

Author

GYOERGY L, MOLNAR J, and DODA M

Subjects
Animals, Cats, Isoproterenol analogs & derivatives, Amphetamine, Amphetamines, Epinephrine, Ergotamine, Neurophysiology, Nictitating Membrane, Pharmacology, Receptors, Adrenergic, beta, Research, Sensory Receptor Cells, Sympathetic Nervous System, Tolazoline
Published
1965

16. THE PHARMACOLOGY OF NEW ADRENERGIC NEURONE BLOCKING AGENTS, N-P-CYCLOHEXYLBENZYLTROPINIUM DERIVATIVES.

Author

DODA M, FEHER O, GYOERGY L, and NADOR K

Subjects
Animals, Cats, Dogs, Rats, Adrenergic Agents, Adrenergic Antagonists, Bretylium Compounds, Neurons, Nictitating Membrane, Pharmacology, Quaternary Ammonium Compounds, Research, Sympatholytics, Tyramine
Abstract

The three N-p-cyclohexylbenzyltropinium derivatives studied gave rise to lasting hypotension after transient stimulation and block of sympathetic ganglia in anaesthetized and conscious animals. The drugs inhibited the contractions of the nictitating membrane and spleen evoked by pre- or postganglionic nerve stimulation. In adrenalectomized animals the pressor effect of tetramethylammonium, the hypertensive response to carotid arterial occlusion and the effect of tyramine on the nictitating membrane were also reduced. The drugs have slight or no parasympathomimetic, parasympatholytic or curare-like side-effects. The bretylium-like action of the compounds is discussed.

Published
1963

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