98 results on '"L. Boissiere"'
Search Results
2. Cluster analysis of a database of surgically managed adult spine deformity (ASD)patients: Determining the minimal clinically important difference (MCID) for each cluster, comparing two clustering approaches
- Author
-
I. Obeid, D. Larrieu, A. Baroncini, A. Bourghli, J. Pizones, F. Pellise, F. KleinstÜCk, A. Alanay, and L. Boissiere
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
- Full Text
- View/download PDF
3. Factors explaining clinical improvement beyond the minimal clinical important difference (MCID) in clusters of adult spine deformity (ASD) patients
- Author
-
I. Obeid, D. Larrieu, A. Baroncini, A. Bourghli, J. Pizones, F. Pellise, F. KleinstÜCk, A. Alanay, and L. Boissiere
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
- Full Text
- View/download PDF
4. Validation of a new method for the radiological measurement of rod curvature in patients with spine deformity
- Author
-
L. Boissiere, D. Larrieu, A. Baroncini, C. Roscop, A. Bourghli, and I. Obeid
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
- Full Text
- View/download PDF
5. Adult spinal deformity (ASD): The ROC method to calculate the Minimal Clinically Important Difference (MCID)
- Author
-
D. Larrieu, A. Baroncini, A. Bourghli, J. Pizones, F. Pellise, F. KleinstÜCk, A. Alanay, L. Boissiere, and I. Obeid
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
- Full Text
- View/download PDF
6. Comparison of coronal and sagittal alignment in normal individuals and moderate scoliosis
- Author
-
Y.P. Charles, A. Gharbi, P. Lamotte-Paulet, C. Aleman, M. Tamir, L. Boissiere, D. Larrieu, M. Huneidi, and I. Obeid
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
- Full Text
- View/download PDF
7. Evaluating information given by large language models in adolescent idiopathic scoliosis patient education: The perspective evaluating content, clarity and empathy
- Author
-
S. Lang, J. Vitale, L. Boissiere, Y.P. Charles, A. Yucekul, C. Yilgor, S. Núñez-Pereira, S. Haddad, A. Gomez-Rice, J. Mehta, F. Galbusera, T. Fekete, J. Pizones, F. Pellise, I. Obeid, A. Alanay, F. Kleinstück, and M. Loibl
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
- Full Text
- View/download PDF
8. Influence of implant density on mechanical complications in adult spinal deformity surgery
- Author
-
Y.P. Charles, F. Séverac, S. Núñez-Pereira, S. Haddad, F. Pellise, I. Obeid, L. Boissiere, C. Yilgor, A. Yucekul, A. Alanay, F. Kleinstück, M. Loibl, R. Raganato, F. Sanchez Perez-Grueso, J. Pizones, and E.S.S.G. Essg
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
- Full Text
- View/download PDF
9. Factors Explaining Mechanical Complications with Revision in Clustered Groups of Patients with Adult Spine Deformity (ASD) Undergoing Surgery
- Author
-
A. Baroncini, D. Larrieu, A. Bourghli, J. Pizones, F. Pellise, F. Kleinstück, A. Alanay, L. Boissiere, and I. Obeid
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
- Full Text
- View/download PDF
10. Comparison of Two Clustering Approaches for Adult Spine Deformity (ASD): Significance of Variable Choice
- Author
-
L. Boissiere, D. Larrieu, A. Baroncini, A. Bourghli, J. Pizones, F. Pellise, F. Kleinstück, A. Alanay, and I. Obeid
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
- Full Text
- View/download PDF
11. Reliability of a New Digital Tool for Photographic Analysis in Quantifying Body Asymmetry in Scoliosis
- Author
-
J. Pizones, L. Moreno-Manzanaro, A. Pupak, S. Núñez-Pereira, D. Larrieu, L. Boissiere, S. Richner-Wunderlin, M. Loibl, T. Zulemyan, A. Yucekul, Y.P. Charles, S. Zgeib, F. Kleinstück, I. Obeid, A. Alanay, F.J. Pérez-Grueso, F. Pellise, and E.S.S.G. Essg
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2024
- Full Text
- View/download PDF
12. The 16-item version of the SRS-instrument shows better structural validity than the 20-item version in young patients with spinal deformity
- Author
-
Anne F. Mannion, Achim Elfering, Tamas F. Fekete, Ian Harding, Marco Monticone, Peter Obid, Thomas Niemeyer, Ulf Liljenqvist, Andreas Boss, Laura Zimmermann, Alba Vila-Casademunt, Francisco Pérez-Grueso, Javier Pizones, Ferran Pellise, Sarah Richner-Wunderlin, Frank S. Kleinstück, Ibrahim Obeid, L. Boissiere, Ahmet Alanay, and Juan Bago
- Subjects
Neurology. Diseases of the nervous system ,RC346-429 - Published
- 2021
- Full Text
- View/download PDF
13. Shorter and sweeter: the 16-item version of the SRS questionnaire shows better structural validity than the 20-item version in young patients with spinal deformity
- Author
-
A F, Mannion, A, Elfering, T F, Fekete, I J, Harding, M, Monticone, P, Obid, T, Niemeyer, U, Liljenqvist, A, Boss, L, Zimmermann, A, Vila-Casademunt, F J, Sánchez Pérez-Grueso, J, Pizones, F, Pellisé, S, Richner-Wunderlin, F S, Kleinstück, I, Obeid, L, Boissiere, A, Alanay, and J, Bagó
- Subjects
Adult ,Male ,Adolescent ,Scoliosis ,Surveys and Questionnaires ,Quality of Life ,Humans ,Female ,Factor Analysis, Statistical ,Language - Abstract
In patients with adult spinal deformity, it was previously shown that 16 of the non-management items of the SRS-instrument showed a better fit to the theoretical four-factor model (pain, function, self-image, mental health) than did all 20 items. Whether the same phenomenon is observed in data from younger ( 20y) patients, for whom the questionnaire was originally designed, is not currently known.Confirmatory factor analysis was used to evaluate the factor structure of the 20 non-management items of the SRS-instrument completed by 3618 young patients with spinal deformity (75.5% female; mean age, 15.0 ± 2.0 years) and of its equivalence across language versions (2713 English-speaking, 270 Spanish, 264 German, 223 Italian, and 148 French). The root mean square error of approximation (RMSEA) and comparative fit index (CFI) indicated model fit.Compared with the 20-item version, the 16-item solution significantly increased the fit (p 0.001) across all language versions, to achieve good model fit (CFI = 0.96, RMSEA = 0.06). For both 16-item and 20-item models, equivalence across languages was not reached, with some items showing weaker item-loading for some languages, in particular German and French.In patients with adolescent idiopathic scoliosis, the shorter 16-item version showed a better fit to the intended 4-factor structure of the SRS-instrument. The wording of some of the items, and/or their equivalence across language versions, may need to be addressed. Questionnaire completion can be a burden for patients; if a shorter, more structurally valid version is available, its use should be encouraged.
- Published
- 2021
14. Tomodensitometric bone anatomy of the intervertebral foramen of the lower cervical spine: measurements and comparison of foraminal volume in healthy individuals and patients suffering from cervicobrachial neuralgia due to foraminal stenosis
- Author
-
P, Coudert, G, Lainé, V, Pointillart, C, Damade, L, Boissiere, J M, Vital, B, Bouyer, and O, Gille
- Subjects
Adolescent ,Cervical Vertebrae ,Brachial Plexus Neuritis ,Humans ,Constriction, Pathologic ,Intervertebral Disc ,Tomography, X-Ray Computed - Abstract
Degenerative foraminal stenosis of the cervical spine can lead to cervicobrachial neuralgias. Computed tomography (CT)-scan assists in the diagnosis and evaluation of foraminal stenosis. The main objective of this study is to determine the bony dimensions of the cervical intervertebral foramen and to identify which foraminal measurements are most affected by degenerative disorders of the cervical spine. These data could be applied to the surgical treatment of this pathology, helping surgeons to focus on specific areas during decompression procedures.A descriptive study was conducted between two groups: an asymptomatic one (young people with no evidence of degenerative cervical spine disorders) and a symptomatic one (experiencing cervicobrachial neuralgia due to degenerative foraminal stenosis). Using CT scans, we determined a method allowing measurements of the following foraminal dimensions: foraminal height (FH), foraminal length (FL), foraminal width in its lateral part ((UWPP, MWPP and IWPP (respectively Upper, Medial and Inferior Width of Pedicle Part)) and medial part (UWMP, MWMP and IWMP (respectively Upper, Medial and Inferior Width of Medial Part)), and disk height (DH). Foraminal volume (FV) was calculated considering the above data. Mean volumes were measured in the asymptomatic group and compared to the values obtained in the symptomatic group.Both groups were made up of 10 patients, and a total of 50 intervertebral discs (100 intervertebral foramina) were analyzed in each group. Comparison of C4C5, C5C6 and C6C7 levels between both groups showed several significant decreases in foraminal dimensions (p 0.05) as well as in foraminal volume (p 0.001) in the symptomatic group. The most affected dimensions were UWPP, MWPP, UWMP, MWMP and FV. The most stenotic foraminal areas were the top of the uncus and the posterior edge of the lower plate of the overlying vertebra.Using a new protocol for measuring foraminal volume, the present study refines the current knowledge of the normal and pathological anatomy of the lower cervical spine and allows us to understand the foraminal sites most affected by degenerative stenosis. Those findings can be applied to foraminal stenosis surgeries. According to our results, decompression of the foramen in regard of both uncus osteophytic spurs and inferior plate of the overlying vertebra might be an important step for spinal nerves release.
- Published
- 2021
15. Combined Lumbosacral Fusion in One Stage Using Anterior Then Posterior Approach: Surgical Technique and Results
- Author
-
Barrey, Cédric, primary, L, Boissiere, additional, G, D’acunzi, additional, and G, Perrin, additional
- Published
- 2015
- Full Text
- View/download PDF
16. Impact of radiologic variables on item responses of ODI, SRS22 and SF-36. in adult spinal deformity patients: differential item functioning (DIF) analysis results from a multi-center database
- Author
-
D C, Kieser, S, Yuksel, L, Boissiere, C, Yilgor, D T, Cawley, K, Hayashi, A, Alanay, F S, Kleinstueck, F, Pellise, F J S, Perez-Grueso, Vital, Jean-Marc, A, Bourghli, E R, Acaroglu, and I, Obeid
- Subjects
Adult ,Disability Evaluation ,Treatment Outcome ,Databases, Factual ,Scoliosis ,Surveys and Questionnaires ,Quality of Life ,Humans ,Female ,Middle Aged ,Aged ,Retrospective Studies - Abstract
To determine if responses given to each question of the Scoliosis Research Society-22 (SRS22), Oswestry disability index (ODI) and Short Form-36 (SF-36) questionnaires are influenced by the radiological parameters.Patients enrolled in a multi-centre prospectively collected adult spinal deformity database who had complete SRS22, ODI and SF-36 data at baseline and at one-year follow-up were analysed. The presence of a differential item function of each question within each score in relation to radiological parameters was analysed using a mixed Rasch model with the radiological threshold value(s) determined.Of those patients analysed (n = 1745; 1406 female, average age 51.0 ± 19.8 years), 944 were surgically and 801 were non-surgically treated. For the SRS22, questions (Q) 3, 5 and 18 were sensitive to almost all radiological parameters and the overall score was found sensitive to the Cobb angle. For the ODI, Q3, 6, 9 and 10 were not sensitive to any radiologic parameters whereas Q4 and 5 were sensitive to most. In contrast, only 3 of the SF-36 items were sensitive to radiological parameters.78% of the SRS-22, 60% of the ODI and 8% of the questions in the SF-36 are sensitive to radiological parameters. Sagittal imbalance is independently associated with a poor overall outcome, but affects mental status and function more than pain and self-image. The assembly of questions responsive to radiological parameters may be useful in establishing a connection between changes in radiologic parameters and HRQL.
- Published
- 2020
17. Les métastases hépatiques (et pas les métastases osseuses) ont un impact sur la survie globale du cancer du poumon non à petites cellules (CPNPC) avancé traité par nivolumab (GFPC 04-2016)
- Author
-
Hélène Doubre, Florian Guisier, O. Bylicki, A. Vergnenegre, G. Justeau, G. Le Garff, H. Janicot, S. Vieillot, A. Bizieux, Radj Gervais, H. Morel, Margaux Geier, L. Boissiere, R. Lamy, M. Bernardi, Christos Chouaid, and Chantal Decroisette
- Subjects
Pulmonary and Respiratory Medicine - Abstract
Introduction Chez les patients atteints d’un cancer du poumon non a petites cellules (CPNPC) metastatique, la presence de metastases hepatiques apparait comme un facteur de mauvais pronostic. En revanche, peu de donnees sont publiees sur le role pronostique des metastases osseuses avec les inhibiteurs de points de controle immunitaires. Nous avons etudie l’association entre les sites de la maladie metastatique et la survie globale (SG) chez les patients atteints de CPNPC de stade IIIb ou IV traites par le Nivolumab en traitement de deuxieme ligne ou plus. Methodes Analyse a partir d’une etude multicentrique, observationnelle et prospective: survie globale (SG) apres la premiere injection de nivolumab en fonction de la presence de metastases hepatiques ou osseuses. Resultats Entre juillet 2016 et juillet 2017, 28 centres ont inclus prospectivement 485 patients, âge median: 64,3 ans; hommes: 70,8%; fumeurs ou ex-fumeurs: 91,6%; PS: 0/1: 81,2%; adenocarcinome: 62,3% (KRAS: 27,5%); chimiotherapie de premiere ligne a base de platine: 91,3% (doublet: 76,5%, triplet: 14,8%, chimiotherapie d’entretien: 53,6%), le Nivolumab a ete administre en deuxieme ligne: 63,7% (n = 308) des cas. Au debut du traitement au nivolumab, 63,9% (n = 309) presentaient plus d’un site de metastase, dont 15,1% (n = 73) le cerveau, 32% (n = 155) le foie et 26,1% (n = 126) l’os. La SSP et la SG medianes de la cohorte etaient respectivement de 2 (95% IC: 1,9-2,1) et 9,7 (95% IC: 8,5-11,4) mois. Il n’y a pas de difference significative pour la SG chez les patients avec et sans metastases osseuses: 10,1 (95% IC: 6,3-13,3) et 9,5 (95% IC: 8,4-11,2), p = 0,62, mais une difference significative pour les patients avec et sans metastase hepatique: 5,5 (95% IC: 3,7-9,8) et 10 (95% IC: 8,6-12,1) mois, p = 0,004, respectivement. Conclusion Les metastases osseuses ne semblent pas avoir d’impact sur la survie globale des patients atteints de CPNPC avance traites par le nivolumab, contrairement a certaines etudes retrospectives anterieures. En revanche, les metastases hepatiques sont associees a une survie plus faible.
- Published
- 2021
- Full Text
- View/download PDF
18. 1326P Liver metastasis but not bone metastasis impact overall survival of advanced non-small cell lung cancer (NSCLC) treated by nivolumab (GFPC 04-2016)
- Author
-
O. Bylicki, H. Morel, Margaux Geier, M. Bernardi, A. Vergnenegre, G. Justeau, L. Boissiere, Radj Gervais, A. Bizieux, R. Lamy, G. Le Garff, H. Janicot, Hélène Doubre, Christos Chouaid, S. Vieillot, Chantal Decroisette, and Florian Guisier
- Subjects
Oncology ,medicine.medical_specialty ,business.industry ,Bone metastasis ,non-small cell lung cancer (NSCLC) ,Hematology ,medicine.disease ,Metastasis ,Internal medicine ,Overall survival ,Medicine ,Nivolumab ,business - Published
- 2020
- Full Text
- View/download PDF
19. Does Spinal Surgery in Elderly Patients (Over 80 Years-Old) Lead to More Early Post-Operative Complications Than Lower Limb Prosthetic Surgery?
- Author
-
Laura Marie-Hardy MD, MSc, Marc Khalifé MD, PhD, Raphaël Pietton MD, MSc, Marie-Eva Rollet MD, MSc, L. Boissière MD, MSc, J. Cohen-Bittan MD, and H. Pascal-Moussellard MD, PhD
- Subjects
Geriatrics ,RC952-954.6 - Abstract
Purpose: Patients and surgeons may be reluctant on spinal surgery over 80 years old, fearing medical complications despite the possible improvement on quality of life. However, fewer reservations for lower limb prosthetic surgery (LLPS) seem to be arisen in this population. Is spinal surgery after 80 years-old responsible of more complications than lower limb surgery? Methods: The consecutive files of 164 patients over 80 years that had spinal surgery or LLPS were analyzed. The data collected pre-operatively were demographic, clinical and post-operatively the number and types of medical complications and length of stay. Results: The mean number of medical complications was 1.11 ± 0.6 [0–6] for spinal surgery and 1.09 ± 1.0 [0–3] for LLPS, ( p = 0,87). The length of stay in orthopedic unit was comparable between the two groups: 10.7 ± 4.9 days [2–36] for SS and 10.7 ± 3.0 days [5–11] for LLPS ( p = 0,96). Conclusion: The global rate of peri-operative complications and the length of hospital stay were similar between spinal surgery and lower limb prosthetic surgery. These results may be explained by the rising cooperation between geriatric specialist and surgeons and the development of mini-invasive surgical technics, diminishing the early post-operative complication rates.
- Published
- 2024
- Full Text
- View/download PDF
20. Anterior Bone Loss in an Anterior Cervical Disectomy and Fusion
- Author
-
DC, Kieser, primary, S, Mazas, additional, C, Roscop, additional, D, Cawley, additional, L, Boissiere, additional, I, Obeid, additional, V, Pointillart, additional, JM, Vital, additional, and O, Gille, additional
- Published
- 2019
- Full Text
- View/download PDF
21. Offset sublaminar hook is an efficient tool for the prevention of distal junctional failure after kyphotic deformity correction.
- Author
-
Bourghli A, Boissiere L, Konbaz F, Larrieu D, Almusrea K, and Obeid I
- Abstract
Purpose: To assess the radiological outcomes and complications focusing on distal junctional failure (DJF) of adult spinal deformity patients who underwent thoracolumbar fixation with the use of offset sublaminar hooks (OSH) distally., Methods: Retrospective review of a prospective, multicenter adult spinal deformity database (2 sites). Inclusion criteria were age of at least 18 years, presence of a spinal deformity with thoraco-lumbar instrumentation ending distally with OSH (pelvis excluded), with minimum 2 years of follow-up. Demographic data, spinopelvic parameters, functional outcomes and complications were collected. Data was analyzed using descriptive statistics. Statistical significance was set to p < 0.05., Results: 32 patients met the inclusion criteria, with the main etiologies being Scheuermann kyphosis and post-traumatic kyphosis. There was a significant correction of thoracic or thoraco-lumbar kyphosis (from 83° to 45° in case of posterior column osteotomy, p < 0.001, and from 49° to 11° in case of a three-column osteotomy, p < 0.001). DJF occurred in 9.3% of the patients including 1 patient who presented distal hook dislodgement and 2 patients who presented a compression fracture below the lowest instrumented vertebra. Oswestry Disability Index score improved in the majority of the patients (from 34.3 to 18.1, p < 0.05)., Conclusions: This is the first paper to propose offset sublaminar hook as a safe and efficient tool for protection of the distal end of the construct in kyphotic ASD surgery when not going down to the pelvis. It showed satisfactory radiological and clinical outcome with an acceptable rate of complications and no distal junctional failure that required revision surgery., Competing Interests: Declarations. Conflict of interest: No potential conflicts of interest. Informed consent: Patients signed informed consent regarding publishing their data and X-rays. IRB approval: Institutional Review Board (IRB) approval was obtained prior to initiation of the study., (© 2024. The Author(s), under exclusive licence to Scoliosis Research Society.)
- Published
- 2024
- Full Text
- View/download PDF
22. Surgical management of dysphagia due to diffuse idiopathic skeletal hyperostosis: the role of barium swallow fluoroscopy-a case report.
- Author
-
Bourghli A, Almonla Y, Boissiere L, Konbaz F, Almusrea K, and Obeid I
- Abstract
Background: Diffuse idiopathic skeletal hyperostosis (DISH) is a systemic condition that might lead to dysphagia because of massive osteophytes that may be present at multiple levels. Confirming the symptomatic level to guide surgical management and avoid extensive surgery is important, however, there is no globally accepted consensus on the topic., Case Description: We report the case of a 51-year-old man, with no specific past medical history, who has been complaining of a 3-months pain in the left side of the tongue base with sensation of a lump in the throat and dysphagia. Computed tomography scan confirmed DISH between C4 and C7. Barium swallow fluoroscopy demonstrated indentation of the esophagus only at the level of C4-C5, which guided the surgical management that focused on resecting only the major osteophytes at the level of C4-C5, avoiding extensive approach with its subsequent possible complications, and enabling satisfactory clinical and radiological outcomes., Conclusions: The current case thoroughly illustrated the diagnosis and surgical management in the presence of dysphagia from DISH. Through an anterior pre-vascular approach complete resection of the major osteophytes could be done. Barium swallow fluoroscopy showed very high interest in dynamically demonstrating the main level causing the dysphagia symptoms and also confirming satisfactory esophagus decompression and release after surgery., Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://jss.amegroups.com/article/view/10.21037/jss-24-84/coif). The authors have no conflicts of interest to declare., (2024 AME Publishing Company. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
23. Is the information provided by large language models valid in educating patients about adolescent idiopathic scoliosis? An evaluation of content, clarity, and empathy : The perspective of the European Spine Study Group.
- Author
-
Lang S, Vitale J, Galbusera F, Fekete T, Boissiere L, Charles YP, Yucekul A, Yilgor C, Núñez-Pereira S, Haddad S, Gomez-Rice A, Mehta J, Pizones J, Pellisé F, Obeid I, Alanay A, Kleinstück F, and Loibl M
- Abstract
Purpose: Large language models (LLM) have the potential to bridge knowledge gaps in patient education and enrich patient-surgeon interactions. This study evaluated three chatbots for delivering empathetic and precise adolescent idiopathic scoliosis (AIS) related information and management advice. Specifically, we assessed the accuracy, clarity, and relevance of the information provided, aiming to determine the effectiveness of LLMs in addressing common patient queries and enhancing their understanding of AIS., Methods: We sourced 20 webpages for the top frequently asked questions (FAQs) about AIS and formulated 10 critical questions based on them. Three advanced LLMs-ChatGPT 3.5, ChatGPT 4.0, and Google Bard-were selected to answer these questions, with responses limited to 200 words. The LLMs' responses were evaluated by a blinded group of experienced deformity surgeons (members of the European Spine Study Group) from seven European spine centers. A pre-established 4-level rating system from excellent to unsatisfactory was used with a further rating for clarity, comprehensiveness, and empathy on the 5-point Likert scale. If not rated 'excellent', the raters were asked to report the reasons for their decision for each question. Lastly, raters were asked for their opinion towards AI in healthcare in general in six questions., Results: The responses among all LLMs were 'excellent' in 26% of responses, with ChatGPT-4.0 leading (39%), followed by Bard (17%). ChatGPT-4.0 was rated superior to Bard and ChatGPT 3.5 (p = 0.003). Discrepancies among raters were significant (p < 0.0001), questioning inter-rater reliability. No substantial differences were noted in answer distribution by question (p = 0.43). The answers on diagnosis (Q2) and causes (Q4) of AIS were top-rated. The most dissatisfaction was seen in the answers regarding definitions (Q1) and long-term results (Q7). Exhaustiveness, clarity, empathy, and length of the answers were positively rated (> 3.0 on 5.0) and did not demonstrate any differences among LLMs. However, GPT-3.5 struggled with language suitability and empathy, while Bard's responses were overly detailed and less empathetic. Overall, raters found that 9% of answers were off-topic and 22% contained clear mistakes., Conclusion: Our study offers crucial insights into the strengths and weaknesses of current LLMs in AIS patient and parent education, highlighting the promise of advancements like ChatGPT-4.o and Gemini alongside the need for continuous improvement in empathy, contextual understanding, and language appropriateness., (© 2024. The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
24. Validation of a new method for the radiological measurement of rod curvature in patients with spine deformity.
- Author
-
Larrieu D, Baroncini A, Assi A, Roscop C, Boissiere L, and Obeid I
- Subjects
- Humans, Adolescent, Reproducibility of Results, Adult, Female, Kyphosis diagnostic imaging, Male, Algorithms, Spinal Fusion methods, Spinal Fusion instrumentation, Scheuermann Disease diagnostic imaging, Observer Variation, Spine diagnostic imaging, Spine surgery, Young Adult, Scoliosis diagnostic imaging, Scoliosis surgery, Radiography methods
- Abstract
Purpose: The relationship between rod curvature and postoperative radiographic results is a debated topic. One of the reasons of the heterogeneity of the observed results might reside in the lack of a validated and widely employed method to measure the curvature of the rods. Aim of this study was to present and validate a novel method for rod measurement, which is based on routine X-rays and utilizes a regression algorithm that limits manual measurements and the related errors., Methods: Data from 20 adolescent idiopathic scoliosis/Scheuermann kyphosis (AIS/SK) patients and 35 adult spine deformity (ASD) patients for analysis, with 112 rods in total. An orthogonal reference grid was overlaid on the lateral X-ray; seven points were then marked along each rod and their coordinates recorded in a table. Using these coordinates, a third-order polynomial regression was applied to obtain the rod curvature equation (correlation coefficients > 0.97). Three observers (one surgeon, one experienced and one inexperienced observer) independently applied the developed method to measure the rod angulation of the included patients and performed the measurements twice. The reliability of the method was evaluated in terms of intraclass correlation coefficient (ICC), Bland-Altmann plot and 2S
R ., Results: The intra-observer ICCs for all measurements exceed 0.85, indicating an excellent correlation. For the AIS/SK group, the surgeon showed a slightly lower reliability compared to the other two evaluators (0.93 vs 0.98 and 0.98). However, the surgeon showed a higher reliability in measurements of the rods at the lumbar level, both for L1-S1 and L4-S1 (0.98 vs 0.96 and 0.89; 0.97 vs. 0.85 and 0.91, respectively). The variability also showed excellent results, with a mean variability ranging from 1.09° to 3.76°. The inter-observer ICCs for the three measurement groups showed an excellent reliability for the AIS/SK group (0.98). The reliability was slightly lower but still excellent for the lumbar measurements in ASD patients at L1-S1 (0.89) and L4-S1 (0.83). The results of the 2SR for each measured segment were 4.4° for T5-T11, 5.4° for L1-S1 and 5.5° for L4-S1., Conclusion: The described method represents a reliable and reproducible way to measure rod curvature. This method is based on routine X-rays and utilizes a regression algorithm that limits manual measurements and the related errors., (© 2024. The Author(s), under exclusive licence to Scoliosis Research Society.)- Published
- 2024
- Full Text
- View/download PDF
25. Comparison of Patients with and without Predicted Surgical Indication between Clusters of Adult Spine Deformity (ASD) Patients.
- Author
-
Baroncini A, Boissiere L, Larrieu D, Haddad S, Pellisé F, Alanay A, Kleinstueck F, Pizones J, Bourghli A, and Obeid I
- Abstract
Study Design: Multicentric, retrospective analysis of prospectively collected data., Objective: To utilize machine-learning (ML) for clustering and management prediction (conservative vs. operative) in surgically treated adult spine deformity (ASD) patients, and to compare the attainment of the Minimum Clinically Important Difference (MCID) between predicted surgical and conservative patients., Summary of Background Data: Management choice in ASD is complex. ML can identity patient clusters and predicted treatment, but it is unclear whether patients treated according to the prediction also show better clinical outcomes., Methods: ASD patients (2-year follow-up) were divided into groups using k-means clustering. Management choice was predicted among operated patients in each cluster. The MCID for the Oswestry Disability Index (ODI) and the Scoliosis Research Society-22 (SRS-22) was calculated and compared between patients with and without surgical prediction., Results: In Cluster 1 (idiopathic scoliosis, n=675, 150 surgeries), 57% of patients had a conservative prediction. Of these, 52% and 49% achieved MCID for ODI and SRS-22, respectively, compared to 68% and 75% for those with surgical predictions (OR=2 and 3.1, respectively).In Cluster 2 (moderate sagittal imbalance, n=561, 200 surgeries), 12% had a conservative prediction. Of these, 29% and 46% achieved MCID for ODI and SRS-22, respectively, compared to 47% and 56% for those with surgical predictions.In Cluster 3 (significant sagittal imbalance, n=537, 197 surgeries), 17% had a conservative prediction. Of these, 12% and 15% achieved MCID for ODI and SRS-22, respectively, compared to 37% and 45% for those with surgical predictions (OR=4.2 and 4.5, respectively)., Conclusion: Patients with a concordant surgical prediction and management had higher odds of achieving the MCID, indicating a good correlation between prediction and clinical outcomes. In Cluster 3, the low percentage of patients with conservative prediction achieving the MCID suggests that machine learning could well identify patients with poor clinical outcomes., Competing Interests: Conflict of interest: AlBa, DL, SH, CR, AnBu: none; LB Consultant: Spineart, Spinevision; IO: Royalties : Spineart, alphatec, Clariance, Consultant : Medtronic, Depuy, spinevision Research support : Medtronic, Depuy; JP Consultant: Medtronic, Grants: medtronic Depuy; FP: Research support: DePuySpine Synthes / Medtronic / Nuvasive / Orthofix / SpineArt Consultant: Medtronic / Nuvasive; AA: Consultancy: Globus, Zimvie, Research Grant: Depuy, Medtronic Royalty: Zimvie; FK: Depuy Spine Speakers Bureau and Research Grant; YPC: Consultant: Clariance, Stryker, Ceraver, Spinevision, Research Grants: Clariance, Stryker, Medtronic; CY: Consultant, Medtronic. All conflict of interest are not relevant to the present study., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
26. Prospective same day discharge instrumented lumbar spine surgery - a forty patient consecutive series.
- Author
-
Boissiere L, Haleem S, Liquois F, Aunoble S, Cursolle JC, Régnault de la Mothe G, Petit M, Pellet N, Bourghli A, Larrieu D, and Obeid I
- Subjects
- Humans, Male, Female, Adult, Middle Aged, Prospective Studies, Aged, Young Adult, Postoperative Complications epidemiology, Adolescent, Lumbar Vertebrae surgery, Spinal Fusion methods, Ambulatory Surgical Procedures methods, Patient Discharge statistics & numerical data
- Abstract
Purpose: Outpatient lumbar decompression surgeries have been successfully performed in France for over twenty years, earning acceptance. However, outpatient instrumented lumbar spine procedures and arthroplasties are less documented. This study aimed to evaluate the feasibility, efficiency, and safety of outpatient lumbar instrumented surgery., Methods: A prospective single-center study involving three experienced surgeons was conducted from September 2020 to September 2021, with a minimum six-month postoperative follow-up. Inclusion criteria comprised patients aged 18 to 75 eligible for same-day discharge, undergoing single-level lumbar spinal fusion or arthroplasty via anterior or posterior Wiltse approach. The primary endpoint was assessing the percentage of successful outpatient discharges (within twelve hours), with secondary endpoints including perioperative/postoperative complications and discharge pain prescriptions in terms of frequency and severity., Results: Forty patients (mean age: 44 years; 16/24 male/female ratio) underwent surgery, including 18 lumbar arthroplasties, twelve ALIF, and ten TLIF procedures. The majority of surgeries were performed at L4-L5 (18 procedures) and L5-S1 levels (22 procedures). 95% (38/40) of patients were successfully discharged within twelve hours, with only two patients discharged the following day. No postoperative hematomas, serious adverse events, or revision surgeries were noted., Conclusion: 95% of patients were discharged successfully within twelve hours following outpatient lumbar fusion surgery, with a 100% patient satisfaction rate. Specific technical solutions were not necessary, and oral pain relief sufficed. Patient selection and education, including early pain management, played crucial roles in complication avoidance. This study underscores the safety of outpatient instrumented lumbar spine procedures, leading to cost reduction and expedited recovery., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2024
- Full Text
- View/download PDF
27. Primary Pelvic Anteversion: Definition, Relevance, and History After Surgery for Adult Spine Deformity.
- Author
-
Baroncini A, Boissiere L, Yilgor C, Larrieu D, Alanay A, Pellisé F, Kleinstueck F, Pizones J, Charles YP, Roscop C, Bourghli A, and Obeid I
- Subjects
- Humans, Female, Male, Adult, Middle Aged, Retrospective Studies, Aged, Pelvis surgery, Pelvis diagnostic imaging, Spinal Curvatures surgery, Spinal Curvatures diagnostic imaging, Spine surgery, Spine diagnostic imaging, Pelvic Bones diagnostic imaging, Pelvic Bones surgery, Young Adult, Postoperative Complications etiology, Postoperative Complications epidemiology, Scoliosis surgery, Scoliosis diagnostic imaging
- Abstract
Study Design: Retrospective analysis of prospectively collected data., Objective: To identify the best definition of primary anteverted pelvis in the setting of adult spine deformity (ASD), and to investigate whether this is a pathologic setting that requires surgical correction., Summary of Background Data: While pelvic retroversion has been thoroughly investigated, pelvic anteversion (AP) is a far lesser discussed topic. Four different AP definitions have been proposed, and AP has been described as a normal or pathologic entity by different authors., Materials and Methods: All patients consulting for ASD at the five participating sites were included. First, the four definitions of AP were compared with descriptive statistics (anatomic method-Pelvic Tilt <0°; Relative Pelvic Version method-RPV >5°; Roussouly method-Pelvic Incidence (PI)<50° and Sacral Slope (SS)>35°); low PT method-PT/PI <25th percentile). Second a subgroup analysis among operated AP patients with a two-year follow-up was performed. Complication rate, radiographic parameters, and clinical scores (ODI, SF-36) were compared in a multivariate analysis between patients who did and did not maintain an AP at the 2-year follow-up., Results: A total of 1163 patients were available for the first analysis. The RPV method seemed to be the most appropriate to define AP in ASD patient. For the second analysis, data on 410 subjects were available, and most of them were young adults with idiopathic scoliosis that did not require pelvic fixation. AP patients who maintained an AP after ASD surgery presented comparable radiographic and clinical outcomes to the patients who presented a normoverted/retroverted pelvis after surgery., Conclusions: According to the results of the presented study, the RPV method is the most appropriate to define primary AP, which is not a pathologic condition and is most often observed in young adults with idiopathic scoliosis. Anteverted pelvis does not require direct surgical correction in this patient group., Competing Interests: LB Consultant: Spineart, Spinevision; I.O.: Royalties : Spineart, alphatec, Clariance, Consultant : Medtronic, Depuy, spinevision Research support : Medtronic, Depuy; JP Consultant: Medtronic, Grants: Medtronic Depuy; F.P.: Research support: DePuySpine Synthes/Medtronic/Nuvasive/Orthofix/SpineArt Consultant: Medtronic/Nuvasive; A.A.: Consultancy: Globus, Zimvie, Research Grant: Depuy, Medtronic Royalty: Zimvie; F.K.: Depuy Spine Speakers Bureau and Research Grant; YPC: Consultant: Clariance, Stryker, Ceraver, Spinevision, Research Grants: Clariance, Stryker, Medtronic; C.Y.: Consultant, Medtronic. The remaining authors report no conflicts of interest., (Copyright © 2024 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2024
- Full Text
- View/download PDF
28. Lumbar pedicle subtraction osteotomy: techniques and outcomes.
- Author
-
Bourghli A, Boissiere L, and Obeid I
- Abstract
Pedicle subtraction osteotomy has been thoroughly described and studied over the past 2 decades, being applied mainly in the lumbar spine, followed by the thoracic spine. Our better understanding of alignment biomechanics, and the progressive refinements of the surgical technique over time made it a very efficient procedure for the management of fixed sagittal malalignment. However, a long learning curve is mandatory to mitigate the associated risks particularly neurological deficits and achieve satisfactory clinical and radiological outcomes with an acceptable rate of complications., Competing Interests: The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper., (© 2024 The Author(s).)
- Published
- 2024
- Full Text
- View/download PDF
29. Proximal junctional kyphosis after adult spinal deformity operated patients with long fusion to the pelvis. Does the type of proximal anchor matter?
- Author
-
Bourghli A, Boissiere L, Larrieu D, Pizones J, Alanay A, Pellisé F, Kleinstück F, and Obeid I
- Subjects
- Humans, Male, Female, Middle Aged, Retrospective Studies, Adult, Aged, Postoperative Complications etiology, Postoperative Complications epidemiology, Pelvis surgery, Pelvis diagnostic imaging, Thoracic Vertebrae surgery, Thoracic Vertebrae diagnostic imaging, Kyphosis surgery, Kyphosis diagnostic imaging, Spinal Fusion adverse effects, Spinal Fusion methods
- Abstract
Purpose: To assess, in a large population of Adult Spinal Deformity (ASD) patients, the true interest of varying the upper anchors as a protective measure against Proximal Junctional Kyphosis (PJK), by analyzing and comparing 2 groups of patients defined according to their proximal construct. Another objective of the study is to look for any other factors, radiological or clinical, that would affect the occurrence of the proximal failure., Methods: Retrospective review of a prospective ASD database collected from 5 centers. Inclusion criteria were age of at least 18 years, presence of a spinal deformity with instrumentation from T12 or above to the pelvis, with minimum 2 years of follow-up. Demographic data, spinopelvic parameters, functional outcomes and complications were collected. Multiple logistic regression analysis was performed to identify the risk factors that would affect the occurrence of PJK., Results: 254 patients were included. 166 in the group "screws proximally" (SP) and 88 in the group "hooks proximally" (HP). There was no difference between both groups for PJK (p = 0.967). The occurrence of PJK was rather associated with greater age and BMI, higher preoperative kyphosis, worst preoperative SRS22 and SF36 scores, greater postoperative Sagittal Vertical Axis (SVA), coronal malalignment and kyphosis., Conclusion: The use of proximal hooks was not effective to prevent PJK after ASD surgery, when compared to proximal screws. Worse preoperative functional outcomes and worse postoperative sagittal and also coronal malalignment were the main drivers for the occurrence of PJK regardless the type of proximal implant., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2024
- Full Text
- View/download PDF
30. Calculation of the minimal clinically important difference in operated patients with adult spine deformity: advantages of the ROC method and significance of prevalence in threshold selection.
- Author
-
Larrieu D, Baroncini A, Bourghli A, Pizones J, Kleinstueck FS, Alanay A, Pellisé F, Charles YP, Boissiere L, and Obeid I
- Subjects
- Humans, Female, Male, Middle Aged, Adult, Aged, ROC Curve, Quality of Life, Prevalence, Prospective Studies, Minimal Clinically Important Difference
- Abstract
Purpose: The Minimal Clinically Important Difference (MCID) is crucial to evaluate management outcomes, but different thresholds have been obtained in different works. Part of this variability is due to measurement error and influence of the database, both essential for calculating the MCID. The aim of this study was to introduce the association of the ROC method in the anchor-based MCID calculation for ODI, SRS-22r, and SF-36, to objectively set the threshold for the anchor-based MCID in an adult spine deformity (ASD) population., Methods: Multicentric study based on a prospective database of consecutively operated ASD patients. An anchor question was used to assess patients' quality of life after surgery. Different approaches were used to calculate the MCID and then compared: SEM (Standard Error of Measurement), MDC (Minimal Detectable Change), and anchor-based MCID with ROC method., Results: 516 patients were included. Those who responded with 6 and 7 to the anchor question were considered improved. The MCID ranges obtained with the ROC method exhibited the lowest variability. Prediction error rates ranged from 31% (SRS-22r) to 41% (SF-36 MCS). The MCID ranges spanned between 12 and 15 for ODI, 0.6 and 0.73 for SRS-22r, 6.62 and 7.41 for SF-36 PCS, and between 2.69 and 5.63 for SF-36 MCS., Conclusion: The ROC method proposes an MCID range with error rate, and can objectively determine the threshold for distinguishing improved and non-improved patients. As the MCID correlates with the utilized database and error of measurement, each study should compute its own MCID for each PROM to allow comparison among different publications., Level of Evidence: II., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2024
- Full Text
- View/download PDF
31. Sagittal alignment of diverse mechanical complications following adult spinal deformity surgery.
- Author
-
Pan C, Bourghli A, Larrieu D, Boissiere L, Pizones J, Alanay A, PelIise F, Kleinstück F, and Obeid I
- Subjects
- Humans, Female, Male, Middle Aged, Aged, Adult, Lordosis surgery, Lordosis diagnostic imaging, Lordosis etiology, Spinal Fusion adverse effects, Spinal Fusion instrumentation, Spinal Fusion methods, Spinal Curvatures surgery, Spinal Curvatures diagnostic imaging, Retrospective Studies, Lumbar Vertebrae surgery, Lumbar Vertebrae diagnostic imaging, Thoracic Vertebrae surgery, Thoracic Vertebrae diagnostic imaging, Postoperative Complications etiology, Postoperative Complications epidemiology, Kyphosis surgery, Kyphosis etiology, Kyphosis diagnostic imaging
- Abstract
Purpose: To compare the sagittal alignment of patients with diverse mechanical complications (MCs) following adult spinal deformity (ASD) surgery with that of patients without MCs., Methods: A total of 371 patients who underwent ASD surgery were enrolled. The sagittal spinopelvic parameters were measured preoperatively and at the 6-month and last follow-up, and the global alignment and proportion (GAP) score was calculated. The subjects were divided into non-MC and MCs groups, and the MCs group was further divided into rod fracture (RF), screw breakage (SB), screw dislodgement (SD) and proximal junctional kyphosis (PJK) subgroups., Results: Preoperatively, the RF group had greater thoracolumbar kyphosis (TLK) and relative upper lumbar lordosis (RULL); the SB group had the largest pelvic incidence (PI) and lumbar lordosis (LL); the SD group had the least global sagittal imbalance; and the PJK group had the highest thoracic kyphosis (TK), TLK and RULL. At the last follow-up, the RF and SB groups featured a large PI minus LL (PI-LL), while the PJK group featured a prominent TK; all the MCs subgroups had sagittal malalignment and a higher GAP score, and the SB group had the most severe cases. Logistic regressions showed that the relative spinopelvic alignment (RSA) score was correlated with RF, SB and SD, while the RSA and age scores were associated with PJK., Conclusion: Each patient with MCs had individual characteristics in the sagittal plane following ASD surgery, which may be helpful to understand the pathophysiology of poor sagittal alignment with its subsequent MCs and guide an eventual revision strategy., (© 2024. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2024
- Full Text
- View/download PDF
32. Reliability of a New Digital Tool for Photographic Analysis in Quantifying Body Asymmetry in Scoliosis.
- Author
-
Pizones J, Moreno-Manzanaro L, Pupak A, Núñez-Pereira S, Larrieu D, Boissiere L, Richner-Wunderlin S, Loibl M, Zulemyan T, Yücekul A, Zgheib S, Charles YP, Chang DG, Kleinstueck F, Obeid I, Alanay A, Sánchez Pérez-Grueso FJ, Pellisé F, and On Behalf Of The Essg
- Abstract
Background: Advancements in non-ionizing methods for quantifying spinal deformities are crucial for assessing and monitoring scoliosis. In this study, we analyzed the observer variability of a newly developed digital tool for quantifying body asymmetry from clinical photographs. Methods: Prospective observational multicenter study. Initially, a digital tool was developed using image analysis software, calculating quantitative measures of body asymmetry. This tool was integrated into an online platform that exports data to a database. The tool calculated 10 parameters, including angles (shoulder height, axilla height, waist height, right and left waistline angles, and their difference) and surfaces of the left and right hemitrunks (shoulders, waists, pelvises, and total). Subsequently, an online training course on the tool was conducted for twelve observers not involved in its development (six research coordinators and six spine surgeons). Finally, 15 standardized back photographs of adolescent idiopathic scoliosis patients were selected from a multicenter image bank, representing various clinical scenarios (different age, gender, curve type, BMI, and pre- and postoperative images). The 12 observers measured the photographs at two different times with a three-week interval. For the second round, the images were randomly mixed. Inter- and intra-observer variabilities of the measurements were analyzed using intraclass correlation coefficients (ICCs), and reliability was measured by the standard error of measurement (SEM). Group comparisons were made using Student's t -test. Results: The mean inter-observer ICC for the ten measurements was 0.981, the mean intra-observer ICC was 0.937, and SEM was 0.3-1.3°. The parameter with the strongest inter- and intra-observer validity was the difference in waistline angles 0.994 and 0.974, respectively, while the highest variability was found with the waist height angle 0.963 and 0.845, respectively. No test-retest differences ( p > 0.05) were observed between researchers (0.948 ± 0.04) and surgeons (0.925 ± 0.05). Conclusion: We developed a new digital tool integrated into an online platform demonstrating excellent reliability and inter- and intra-observer variabilities for quantifying body asymmetry in scoliosis patients from a simple clinical photograph. The method could be used for assessing and monitoring scoliosis and body asymmetry without radiation.
- Published
- 2024
- Full Text
- View/download PDF
33. Effects of indirect foraminal decompression during anterior cervical disc fusion procedure: preliminary results of a prospective study with clinical and radiological outcomes.
- Author
-
Lainé G, Coudert P, Damade C, Boissiere L, Pointillart V, Vital JM, Bouyer B, and Gille O
- Subjects
- Humans, Prospective Studies, Decompression, Surgical methods, Constriction, Pathologic surgery, Treatment Outcome, Cervical Vertebrae diagnostic imaging, Cervical Vertebrae surgery, Retrospective Studies, Brachial Plexus Neuritis surgery, Spinal Diseases surgery, Spinal Fusion methods
- Abstract
Introduction: The respective effects of direct and indirect decompression in the clinical outcome after anterior cervical disc fusion (ACDF) is still debated. The main purpose of this study was to analyze the effects of indirect decompression on foraminal volumes during ACDF performed in patients suffering from cervico-brachial neuralgias due to degenerative foraminal stenosis, i.e. to determine whether implant height was associated with increased postoperative foraminal height and volume., Methods: A prospective follow-up of patients who underwent ACDF for cervicobrachial neuralgias due to degenerative foraminal stenosis was conducted. Patient had performed a CT-scan pre and post-operatively. Disc height, foraminal heights and foraminal volumes were measured pre and post operatively., Results: 37 cervical disc fusions were successfully performed in 20 patients, with a total of 148 foramina studied. Foraminal height and volume were measured bilaterally on the pre- and post-operative CT scans (148 foramina studied). After univariate analysis, it was found a significant improvement for every radiological parameter, with a significant increase in disc height, foraminal height and foraminal volume being respectively +3,22 mm (p < 0,001), +2,12 mm (p < 0,001) and +54 mm
3 (p < 0,001). Increase in disc height was significantly associated with increase in foraminal height (p < 0,001) and foraminal volume (p < 0,001). At the same time, increase in foraminal height was significantly correlated with foraminal volume (p < 0,001), and seems to be the major component affecting increasing in foraminal volume., Conclusion: Indirect decompression plays an important part in the postoperative foraminal volume increase after ACDF performed for cervicobrachial neuralgias., (Copyright © 2023 Elsevier Masson SAS. All rights reserved.)- Published
- 2024
- Full Text
- View/download PDF
34. Rod Angulation Relationship with Thoracic Kyphosis after Adolescent Idiopathic Scoliosis Posterior Instrumentation.
- Author
-
Boissiere L, Bourghli A, Guevara-Villazon F, Pellisé F, Alanay A, Kleinstück F, Pizones J, Roscop C, Larrieu D, and Obeid I
- Abstract
Introduction: Surgery to correct spinal deformities in scoliosis involves the use of contoured rods to reshape the spine and correct its curvatures. It is crucial to bend these rods appropriately to achieve the best possible correction. However, there is limited research on how the rod bending process relates to spinal shape in adolescent idiopathic scoliosis surgery., Methods: A retrospective study was conducted using a prospective multicenter scoliosis database. This study included adolescent idiopathic scoliosis patients from the database who underwent surgery with posterior instrumentation covering the T4 to T12 segments. Standing global spine X-rays were used in the analysis. The sagittal Cobb angles between T5 and T11 were measured on the spine. Additionally, the curvature of the rods between T5 and T11 was measured using the tangent method. To assess the relationship between these measurements, the difference between the dorsal kyphosis (TK) and the rod kyphosis (RK) was calculated (ΔK = TK - RK). This study aimed to analyze the correlation between ΔK and various patient characteristics. Both descriptive and statistical analyses were performed to achieve this goal., Results: This study encompassed a cohort of 99 patients, resulting in a total of 198 ΔK measurements for analysis. A linear regression analysis was conducted, revealing a statistically significant positive correlation between the kyphosis of the rods and that of the spine (r = 0.77, p = 0.0001). On average, the disparity between spinal and rod kyphosis averaged 5.5°. However, it is noteworthy that despite this modest mean difference, there was considerable variability among the patients. In particular, in 84% of cases, the concave rod exhibited less kyphosis than the spine, whereas the convex rod displayed greater kyphosis than the spine in 64% of cases. It was determined that the primary factor contributing to the flattening of the left rod was the magnitude of the coronal Cobb angle, both before and after the surgical procedure. These findings emphasize the importance of considering individual patient characteristics when performing rod bending procedures, aiming to achieve the most favorable outcomes in corrective surgery., Conclusions: Although there is a notable and consistent correlation between the curvature of the spine and the curvature of the rods, it is important to acknowledge the substantial heterogeneity observed in this study. This heterogeneity suggests that individual patient factors play a significant role in shaping the outcome of spinal corrective surgery. Furthermore, this study highlights that more severe spinal curvatures in the frontal plane have an adverse impact on the shape of the rods in the sagittal plane. In other words, when the scoliosis curve is more pronounced in the frontal plane, it tends to influence the way the rods are shaped in the sagittal plane. This underscores the complexity of spinal deformities and the need for a tailored approach in surgical interventions to account for these variations among patients.
- Published
- 2023
- Full Text
- View/download PDF
35. Fixed coronal malalignment (CM) in the lumbar spine independently impacts disability in adult spinal deformity (ASD) patients when considering the obeid-CM (O-CM) classification.
- Author
-
Boissiere L, Bourghli A, Kieser D, Larrieu D, Alanay A, Pellisé F, Kleinstück F, Loibl M, Pizones J, and Obeid I
- Subjects
- Humans, Adult, Retrospective Studies, Lumbar Vertebrae surgery, Multivariate Analysis, Quality of Life, Scoliosis surgery
- Abstract
Background: Postoperative flatback has been described in detail for sagittal plane considerations over the past 2 decades, and its correlations with disability are now accepted. Fixed Coronal Malalignment (CM) has been less described, and some authors report no significant association with the clinical outcome. The O-CM classification analyses CM and incorporates specific modifiers for each curve type., Purpose: This study evaluates the O-CM classification modifiers according to age, sagittal alignment, and patient-reported outcome measures (PROMs). Our hypothesis is that fixed CM correlates with PROMs independently from sagittal alignment and age., Study Design: Retrospective analysis of a large adult spinal deformity (ASD) database prospectively collected., Patient Sample: We included 747 patients from the database with long lumbar fusion (more than 3 levels), with at least two years of follow-up. Three categories of patients met the inclusion criteria (prior surgery at baseline and no revision surgery afterward, prior surgery at baseline and revision afterward, no prior surgery at baseline but fusion>3 levels and 2 years follow-up)., Outcome Measures: All patients completed the Oswestry Disability Index (ODI), Short Form 36 (SF36), and Scoliosis Research Society 22 scores., Methods: The patients were classified according to the six modifiers of the O-CM classification. Central Sacral Vertical Line (CSVL) above 2, 3, and 4 cm's impact on PROMs was analyzed. Multivariate analysis was performed on the relationship between PROMS and age, global tilt (GT), and CM modifiers., Results: After multivariate analysis using age and GT as confounding factors, we found that CM independently affects PROMs starting at 2 cm offset. Disability increases linearly with CSVL. Patients classified with 2B modifiers have the worst SRS-22 total score, social life, and self-image., Conclusion: In a fused spine, CM independently affects disability in ASD patients. Disability increases linearly with CSVL. Despite previous reports that failed to find correlations of CM with PROMs, our study showed that fixed postoperative CM, according to O-CM classification, correlates independently from sagittal malalignment with worse PROMs., Level of Evidence: III., Competing Interests: Declarations of competing interests One or more of the authors declare financial or professional relationships on ICMJE-TSJ disclosure forms., (Copyright © 2023 Elsevier Inc. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF
36. Rod angulation does not reflect sagittal curvature in adult spinal deformity surgery: comparison of lumbar lordosis and rod contouring.
- Author
-
Boissiere L, Guevara-Villazón F, Bourghli A, Abdallah R, Pellise F, Pizones J, Alanay A, Kleinstueck F, Larrieu D, and Obeid I
- Subjects
- Humans, Adult, Retrospective Studies, Prospective Studies, Spine diagnostic imaging, Spine surgery, Lumbar Vertebrae diagnostic imaging, Lumbar Vertebrae surgery, Lordosis diagnostic imaging, Lordosis surgery, Spinal Fusion methods
- Abstract
Study Design: A retrospective study., Objective: Relationship between rod and spinal shape in the sagittal plane in adult spinal deformity (ASD) surgery., Background: Corrective surgery for adult spinal deformity (ASD) involves the use of contoured rods to correct and modify the spinal curvatures. Adequate rod bending is crucial for achieving optimal correction. The correlation between rods and spinal shape in long constructs has not been reported previously., Methods: We conducted a retrospective analysis of a prospective, multicenter database of patients who underwent surgery for ASD. The inclusion criteria were patients who underwent pelvic fixation and had an upper instrumented vertebra at or above T12. Pre- and post-operative standing radiographs were used to assess lumbar lordosis at the L4S1 and L1S1 levels. The angle between the tangents to the rod at the L1, L4, and S1 pedicles was calculated to determine the L4S1 and L1S1 rod lordosis. The difference between the lumbar lordosis (LL) and the rod lordosis (RL) was calculated as ΔL = LL-RL. The correlation between this difference (ΔL) and various characteristics was analyzed using descriptive and statistical methods., Results: Eighty-three patients were included in the study, resulting in 166 analyzed differences (ΔL) between the rod and spinal lordosis. The values for rod lordosis were found to be both greater and lesser than those of the spine but were mostly lower. The range for total ΔL was -24 °-30.9 °, with a mean absolute ΔL of 7.8 ° for L1S1 (standard deviation (SD) = 6.0) and 9.1 ° for L4S1 (SD = 6.8). In 46% of patients, both rods had a ΔL of over 5 °, and over 60% had at least one rod with a ΔL difference of over 5 °. Factors found to be related to a higher ΔL included postoperative higher lumbar lordosis, presence of osteotomies, higher corrected degrees, older age, and thinner rods. Multivariate analysis correlated only higher postoperative L1S1 lordosis with higher ΔL. No correlation was found between a higher ΔL and sagittal imbalance., Conclusions: Variations between spinal and rod curvatures were observed despite the linear regression correlation. The shape of the rod does not seem to be predictive of the shape of the spine in the sagittal plane in ASD long-construct surgeries. Several factors, other than rod contouring, are involved in explaining the postoperative shape of the spine. The observed variation calls into question the fundamentals of the ideal rod concept., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2023
- Full Text
- View/download PDF
37. Adherence to the Obeid coronal malalignment classification and a residual malalignment below 20 mm can improve surgical outcomes in adult spine deformity surgery.
- Author
-
Baroncini A, Frechon P, Bourghli A, Smith JS, Larrieu D, Pellisé F, Pizones J, Kleinstueck F, Alanay A, Kieser D, Cawley DT, Boissiere L, and Obeid I
- Subjects
- Humans, Adult, Retrospective Studies, Quality of Life, Postoperative Period, Treatment Outcome, Scoliosis diagnostic imaging, Scoliosis surgery
- Abstract
Purpose: Coronal balance is a major factor impacting the surgical outcomes in adult spinal deformity (ASD). The Obeid coronal malalignment (O-CM) classification has been proposed to improve the coronal alignment in ASD surgery. Aim of this study was to investigate whether a postoperative CM < 20 mm and adherence to the O-CM classification could improve surgical outcomes and decrease the rate of mechanical failure in a cohort of ASD patients., Methods: Multicenter retrospective analysis of prospectively collected data on all ASD patients who underwent surgical management and had a preoperative CM > 20 mm and a 2-year follow-up. Patients were divided in two groups according to whether or not surgery had been performed in adherence to the guidelines of the O-CM classification and according to whether or not the residual CM was < 20 mm. The outcomes of interest were radiographic data, rate of mechanical complications and Patient-Reported Outcome Measures., Results: At 2 years, adherence to the O-CM classification led to a lower rate of mechanical complications (40 vs. 60%). A coronal correction of the CM < 20 mm allowed for a significant improvement in SRS-22 and SF-36 scores and was associated with a 3.5 times greater odd of achieving the minimal clinical important difference for the SRS-22., Conclusion: Adherence to the O-CM classification could reduce the risk of mechanic complications 2 years after ASD surgery. Patients with a residual CM < 20 mm showed better functional outcomes and a 3.5 times greater odd of achieving the MCID for the SRS-22 score., (© 2023. The Author(s).)
- Published
- 2023
- Full Text
- View/download PDF
38. Domino connector for thoracic pedicle subtraction osteotomy reduction: surgical technique and patient series.
- Author
-
Bourghli A, Boissiere L, Konbaz F, Larrieu D, Almusrea K, and Obeid I
- Subjects
- Adult, Humans, Female, Male, Retrospective Studies, Thoracic Vertebrae diagnostic imaging, Thoracic Vertebrae surgery, Osteotomy methods, Lumbar Vertebrae surgery, Treatment Outcome, Follow-Up Studies, Lordosis surgery, Kyphosis diagnostic imaging, Kyphosis surgery
- Abstract
Purpose: Different techniques have been previously described to close the pedicle subtraction osteotomy (PSO) site for correction of sagittal malalignment; the use of a side-to-side domino connector as a correction tool in the thoracic spine has not been specifically studied., Methods: Twenty adult patients who underwent single-level thoracic PSO from T1 to T12 were included and retrospectively reviewed (two centers). Preoperative and postoperative full-body X-rays, perioperative data, clinical data and complications were recorded with a minimum 2 years of follow-up. Surgical technique and the nuances in using the domino connector were described in detail., Results: Patients had a mean age of 40y; 40% were female. Two different techniques involving the domino were applied for closure of the PSO site depending on the type of kyphosis (smooth vs. angular deformity). Both techniques provided significant correction of the local kyphosis (from 48° to 18°) with reciprocal reduction of compensatory cervical lordosis (from 37.6° to 18.6°, p < 0.01) in upper thoracic PSO or lumbar lordosis (from 74.5° to 46.6°, p < 0.01) in lower thoracic PSO. Four patients presented postoperative complications that resolved (hemothorax, GI bleeding), and two patients presented transient neurological deficit. Oswestry Disability Index score improved in the majority of the patients (from 32.7 to 22.5, p < 0.05). There were no pseudarthroses, symptomatic instrumentation breakage, or surgical site infection., Conclusion: Use of a side-to-side domino connector in combination with two different rod cantilever techniques is effective for the reduction of thoracic pedicle subtraction osteotomy achieving satisfactory radiological and clinical outcome., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2023
- Full Text
- View/download PDF
39. Does the use of postoperative brace help preventing mechanical complications following adult deformity surgery?
- Author
-
Pizones J, Boissiere L, Moreno-Manzanaro L, Vila-Casademunt A, Perez-Grueso FJS, Sánchez-Márquez JM, Baíllo NF, Kleinstück F, Alanay A, Pellisé F, and Obeid I
- Subjects
- Female, Humans, Adult, Middle Aged, Aged, Male, Prospective Studies, Retrospective Studies, Cohort Studies, Postoperative Complications epidemiology, Postoperative Complications prevention & control, Postoperative Complications etiology, Frailty complications, Spinal Fusion adverse effects
- Abstract
Purpose: There is scarce information regarding the effectiveness of postoperative braces in decreasing mechanical complications and reinterventions following adult deformity surgery., Methods: Retrospective matched cohort study from a prospective adult deformity multicenter database. We selected operated patients, fused to the pelvis, > 6 instrumented levels, and minimum 2 year follow-up. Three hundred and eighty patients were separated into two groups (Brace-3 months TLSO-vs No Brace) and then matched controlling for age, gender and frailty. We studied demographic, intraoperative, and postoperative spinopelvic parameters. Both groups were compared regarding complications and reinterventions in the first 2 postoperative years, using univariate and multivariate logistic regression analysis., Results: We finally analyzed 359 matched patients, mean age of 65.3 ± 8.9 years, frailty-index (0.43 ± 0.15), and mostly females (84%). 224 patients wore a postoperative brace (B) and 135 didn't (NoB). They showed no difference in intraoperative variables and postoperative spinopelvic alignment. They differed (P < 0.05) in: Pelvic incidence (B:58° ± 13 vs NoB:54.5° ± 13); BMI (B:25.8 ± 4 vs NoB:27.4 ± 5); upper instrumented vertebra (B:81.7% T8-L1 vs NoB:72.6% T8-L1), and the use of multiple rods (B:47.3% vs NoB:18.5%). Univariate analysis showed a higher rate of mechanical complications and reinterventions when not using a brace. As well as higher NRS-back and leg pain at 6 weeks. However, multivariate analysis selected the use of multiple rods as the only independent factor protecting against mechanical complications (OR: 0.38; CI 95% 0.22-0.64) and reinterventions (OR: 0.41; CI 95% 0.216-0.783)., Conclusion: After controlling for potential confounders, our study could not identify the protective effect of postoperative braces preventing mechanical complications and reinterventions in the first two postoperative years., (© 2023. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2023
- Full Text
- View/download PDF
40. Long-term opioid medication profile of European adult spinal deformity patients: minimum five years follow-up study.
- Author
-
Abul K, Yilgor C, Yucekul A, Alanay NA, Yavuz Y, Zulemyan T, Boissiere L, Bourghli A, Obeid I, Pizones J, Kleinstueck F, Perez-Grueso FJS, Pellise F, and Alanay A
- Subjects
- Humans, Adult, Analgesics, Opioid adverse effects, Follow-Up Studies, Retrospective Studies, Spine surgery, Opioid-Related Disorders etiology, Spinal Fusion adverse effects
- Abstract
Background Context: There remains significant variability in the use of postoperative opioids. On one end, it is proven that appropriate pain control is a critical aspect of patient management; on the other end, past few decades have been associated with major increases in opioid-related overdoses and addiction treatment. We hypothesized that several pre- and postoperative risk factors affecting long-term opioid use could be identified., Purpose: Evaluation of factors associated with minimum 5-year postoperative opioid use following adult spinal deformity surgery., Study Design/setting: Prospectively followed study group database., Patient Sample: Adult spinal deformity patients who underwent elective spine surgery between 2009 and 2016 were included., Outcome Measures: Opioid usage or otherwise at minimum 5 years follow-up. Use of nonopioid analgesics, weak and strong opioids METHODS: Retrospective analysis of patients undergoing elective spinal deformity surgery. A total of 37 factors comprising patient characteristics, radiographic measurements, operative details, preoperative and early postoperative opioid use, and mechanical complications and revisions were analyzed. Details on identified factors were provided., Results: A total of 265 patients (215F, 50M) from five sites were included. The mean follow-up duration was 68.4±11.7 (60-102) months. On average, 10.6±3.5 levels were fused. Preoperatively, 64 (24.2%) patients were using opioids. The rate of opioid users increased to 33.6% at 6 weeks and decreased to 21.5% at 6 months. During follow-up, there were patients who discontinued opioids, while others have started and/or restarted using opioids. As a result, 59 (22.3%) patients were still on opioids at the latest follow-up. Multivariate analyses showed that factors independently affecting opioid use at an average of 68 months postoperatively, in order of significance, were opioid use at sixth weeks, preoperative opioid use and opioid use at sixth months with the odds ratios of 2.88, 2.51, and 2.38 respectively. At these time points, factors such as age, number of comorbidities, tobacco use, the time of the last prior spine surgery and postoperative sagittal plane alignment affected opioid usage rates., Conclusions: Opioid usage at 6 weeks was found to be more predictive of long-term opioid use compared to preoperative use. Patients should be well informed to have realistic expectations regarding opioid use when considering adult spinal deformity surgery., Competing Interests: Declarations of Competing Interests One or more of the authors declare financial or professional relationships on ICMJE-NASSJ disclosure forms., (Copyright © 2022 Elsevier Inc. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF
41. An age and sex matched study on the effect of obesity on the functional outcomes and complication rates in patients with adult spinal deformity undergoing primary multi-level thoracolumbar spinal fusion.
- Author
-
Kieser DC, Wyatt MC, Boissiere L, Hayashi K, Cawley DT, Yilgor C, Larrieu D, Alanay A, Acaroglu E, Kleinstueck F, Pellisé F, Perez-Grueso FJS, Bourghli A, Vital JM, Gille O, and Obeid I
- Abstract
Background: The objective of this study was to determine the effect of obesity on the functional outcomes and complication rates of patients with adult spinal deformity (ASD) undergoing multi-level thoracolumbar fusion., Methods: An age and sex matched comparison of functional outcomes [Numeric Rating Scale (NRS) back and leg scores, Core Outcome Measurement Index (COMI) back scores, Scoliosis Research Society 22 (SRS22) satisfaction and total scores, Short Form 36 (SF36) general health scores, Physical Component Score (PCS), Mental Component Score (MCS), Oswestry Disability Index (ODI) (including all domains)] at 6 months, 1, 2, 3 and 4 years and the complication rates at final follow-up between obese [body mass index (BMI) >30] and normal BMI (18.5-24.9) patients undergoing more than 3 levels of thoracolumbar fusion with a minimum 2-year follow-up. Patients who had undergone any previous spinal surgery were excluded., Results: Thirty patients were included in each arm of the study. Baseline demographics, including the number of levels fused, were similar between the groups. Estimated blood loss (EBL) was higher in obese patients (1,916 vs. 1,099 mL, P=0.001), but operative time was similar (282 vs. 320 min, P=0.351). The functional outcomes and satisfaction scores were consistently poorer in the obese group at all time-points, but their satisfaction scores were similar. Obese patients had a higher complication rate (OR 3.05, P=0.038) predominantly due to dural tears and nerve root injuries, but a similar reoperation rate., Conclusions: In patients with ASD undergoing multi-level thoracolumbar fusion, obesity results in a higher blood loss, poorer sagittal correction, poorer post-operative functional scores and higher complication rates than patients with a normal BMI. However, obesity does not affect operative times, length of hospital stay or reoperation rates. Furthermore, patients with obesity have similar post-operative satisfaction scores to patients with normal BMIs., Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://aoj.amegroups.com/article/view/10.21037/aoj-22-14/coif). The authors have no conflicts of interest to declare., (2022 Annals of Joint. All rights reserved.)
- Published
- 2022
- Full Text
- View/download PDF
42. Domino connector is an efficient tool to improve lumbar lordosis correction angle after pedicle subtraction osteotomy for adult spinal deformity.
- Author
-
Bourghli A, Boissiere L, Cawley D, Larrieu D, Pizones J, Alanay A, PelIise F, Kleinstück F, and Obeid I
- Subjects
- Adult, Humans, Lumbar Vertebrae diagnostic imaging, Lumbar Vertebrae surgery, Osteotomy methods, Prospective Studies, Retrospective Studies, Treatment Outcome, Kyphosis surgery, Lordosis diagnostic imaging, Lordosis surgery, Spinal Fusion methods
- Abstract
Purpose: To compare the radiological outcomes and complications of adult spinal deformity patients who underwent a pedicle subtraction osteotomy (PSO) below L2 but categorized according to their construct where either a domino connector was applied for osteotomy correction or not., Methods: Retrospective review of a prospective, multicenter adult spinal deformity database (5 sites). Inclusion criteria were adult patients who underwent PSO between L3 and L5 with a minimum follow-up of 2 years. Among 1243 patients in the database, 79 met the inclusion criteria, 41 in the no-domino (ND) group and 38 in the domino (D) group. The domino technique consisted of using 2 parallel rods connected by a domino on one side of the PSO in order to achieve gradual and controlled compression at the osteotomy site. Demographic data, operative parameters, spinopelvic parameters and complications were collected., Results: Demographic data and operative parameters were globally similar between both groups, and they showed a comparable preoperative sagittal malalignment. Segmental lordosis improved by 22° and 31° (p < 0.05) and L1S1 lordosis improved by 23° and 32° (p < 0.05) in the ND and D group, respectively. The use of multiple rods was similar between the groups (58% vs. 57%). Also, mechanical complications rate was globally similar between both groups with no statistically significant difference (22% vs. 28.9%)., Conclusion: Domino connector is a safe, powerful and efficient tool for pedicle subtraction osteotomy site closure. It improved the lumbar lordosis correction angle with an acceptable rate of complications., (© 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2022
- Full Text
- View/download PDF
43. Shorter and sweeter: the 16-item version of the SRS questionnaire shows better structural validity than the 20-item version in young patients with spinal deformity.
- Author
-
Mannion AF, Elfering A, Fekete TF, Harding IJ, Monticone M, Obid P, Niemeyer T, Liljenqvist U, Boss A, Zimmermann L, Vila-Casademunt A, Sánchez Pérez-Grueso FJ, Pizones J, Pellisé F, Richner-Wunderlin S, Kleinstück FS, Obeid I, Boissiere L, Alanay A, and Bagó J
- Subjects
- Adolescent, Adult, Factor Analysis, Statistical, Female, Humans, Language, Male, Surveys and Questionnaires, Quality of Life, Scoliosis
- Abstract
Purpose: In patients with adult spinal deformity, it was previously shown that 16 of the non-management items of the SRS-instrument showed a better fit to the theoretical four-factor model (pain, function, self-image, mental health) than did all 20 items. Whether the same phenomenon is observed in data from younger (< 20y) patients, for whom the questionnaire was originally designed, is not currently known., Methods: Confirmatory factor analysis was used to evaluate the factor structure of the 20 non-management items of the SRS-instrument completed by 3618 young patients with spinal deformity (75.5% female; mean age, 15.0 ± 2.0 years) and of its equivalence across language versions (2713 English-speaking, 270 Spanish, 264 German, 223 Italian, and 148 French). The root mean square error of approximation (RMSEA) and comparative fit index (CFI) indicated model fit., Results: Compared with the 20-item version, the 16-item solution significantly increased the fit (p < 0.001) across all language versions, to achieve good model fit (CFI = 0.96, RMSEA = 0.06). For both 16-item and 20-item models, equivalence across languages was not reached, with some items showing weaker item-loading for some languages, in particular German and French., Conclusion: In patients with adolescent idiopathic scoliosis, the shorter 16-item version showed a better fit to the intended 4-factor structure of the SRS-instrument. The wording of some of the items, and/or their equivalence across language versions, may need to be addressed. Questionnaire completion can be a burden for patients; if a shorter, more structurally valid version is available, its use should be encouraged., (© 2022. The Author(s), under exclusive licence to Scoliosis Research Society.)
- Published
- 2022
- Full Text
- View/download PDF
44. Surgical correction of a previously operated juvenile idiopathic scoliosis with crankshaft phenomenon: an illustrative case report.
- Author
-
Bourghli A, Boissiere L, Al Araki A, Alsofyani MA, and Obeid I
- Abstract
Background: Crankshaft phenomenon secondary to posterior fusion for scoliotic deformity at a young age has become rare and its management can be very challenging., Case Description: We report the case of an 11-year-old girl who has been complaining of a progressively increasing hump in her back with waist and shoulders asymmetry during the past 6 months. Three years prior to presentation, she underwent in another institution posterior correction fusion from T3 to L3 for a juvenile idiopathic scoliosis with a Cobb angle of 60°. After the initial correction, follow-up X-rays revealed a progressive increase of the scoliosis angulation with the onset of a coronal malalignment mainly at the cervicothoracic junction. Full spine anteroposterior and lateral X-rays revealed a long right thoracolumbar scoliosis of 70° with a rib-vertebra angle difference of 27° and the proximal right screw pulled out from the rod. CT scan confirmed the posterior fusion between the apical vertebras. MRI did not show any congenital anomaly. The patient underwent a revision surgery with instrumentation from T1 to L4, and posterior column osteotomies at 6 levels between T4 and T10. Coronal Cobb angle corrected to 11° with satisfactory sagittal alignment and a maintained correction at 3 years of follow-up., Conclusions: This is the first case to thoroughly illustrate surgical management in the onset of a crankshaft phenomenon. Through a posterior-only approach, the use of posterior column osteotomies at the apex of the deformity in order to release the previous fusion is a safe and satisfactory option to reestablish proper coronal and sagittal alignment, with satisfactory clinical and radiological long-term results., Competing Interests: Conflicts of Interest: All authors have completed the ICMJE uniform disclosure form (available at https://jss.amegroups.com/article/view/10.21037/jss-22-31/coif). The authors have no conflicts of interest to declare., (2022 Journal of Spine Surgery. All rights reserved.)
- Published
- 2022
- Full Text
- View/download PDF
45. Correction: Shorter and sweeter: the 16-item version of the SRS questionnaire shows better structural validity than the 20-item version in young patients with spinal deformity.
- Author
-
Mannion AF, Elfering A, Fekete TF, Harding IJ, Monticone M, Obid P, Niemeyer T, Liljenqvist U, Boss A, Zimmermann L, Vila-Casademunt A, Pérez-Grueso FJS, Pizones J, Pellisé F, Richner-Wunderlin S, Kleinstück FS, Obeid I, Boissiere L, Alanay A, and Bagó J
- Published
- 2022
- Full Text
- View/download PDF
46. Tomodensitometric bone anatomy of the intervertebral foramen of the lower cervical spine: measurements and comparison of foraminal volume in healthy individuals and patients suffering from cervicobrachial neuralgia due to foraminal stenosis.
- Author
-
Coudert P, Lainé G, Pointillart V, Damade C, Boissiere L, Vital JM, Bouyer B, and Gille O
- Subjects
- Adolescent, Cervical Vertebrae diagnostic imaging, Cervical Vertebrae surgery, Constriction, Pathologic, Humans, Tomography, X-Ray Computed, Brachial Plexus Neuritis pathology, Intervertebral Disc
- Abstract
Purpose: Degenerative foraminal stenosis of the cervical spine can lead to cervicobrachial neuralgias. Computed tomography (CT)-scan assists in the diagnosis and evaluation of foraminal stenosis. The main objective of this study is to determine the bony dimensions of the cervical intervertebral foramen and to identify which foraminal measurements are most affected by degenerative disorders of the cervical spine. These data could be applied to the surgical treatment of this pathology, helping surgeons to focus on specific areas during decompression procedures., Methods: A descriptive study was conducted between two groups: an asymptomatic one (young people with no evidence of degenerative cervical spine disorders) and a symptomatic one (experiencing cervicobrachial neuralgia due to degenerative foraminal stenosis). Using CT scans, we determined a method allowing measurements of the following foraminal dimensions: foraminal height (FH), foraminal length (FL), foraminal width in its lateral part ((UWPP, MWPP and IWPP (respectively Upper, Medial and Inferior Width of Pedicle Part)) and medial part (UWMP, MWMP and IWMP (respectively Upper, Medial and Inferior Width of Medial Part)), and disk height (DH). Foraminal volume (FV) was calculated considering the above data. Mean volumes were measured in the asymptomatic group and compared to the values obtained in the symptomatic group., Results: Both groups were made up of 10 patients, and a total of 50 intervertebral discs (100 intervertebral foramina) were analyzed in each group. Comparison of C4C5, C5C6 and C6C7 levels between both groups showed several significant decreases in foraminal dimensions (p < 0.05) as well as in foraminal volume (p < 0.001) in the symptomatic group. The most affected dimensions were UWPP, MWPP, UWMP, MWMP and FV. The most stenotic foraminal areas were the top of the uncus and the posterior edge of the lower plate of the overlying vertebra., Conclusion: Using a new protocol for measuring foraminal volume, the present study refines the current knowledge of the normal and pathological anatomy of the lower cervical spine and allows us to understand the foraminal sites most affected by degenerative stenosis. Those findings can be applied to foraminal stenosis surgeries. According to our results, decompression of the foramen in regard of both uncus osteophytic spurs and inferior plate of the overlying vertebra might be an important step for spinal nerves release., (© 2022. The Author(s), under exclusive licence to Springer-Verlag France SAS, part of Springer Nature.)
- Published
- 2022
- Full Text
- View/download PDF
47. Impact of radiologic variables on item responses of ODI, SRS22 and SF-36. in adult spinal deformity patients: differential item functioning (DIF) analysis results from a multi-center database.
- Author
-
Kieser DC, Yuksel S, Boissiere L, Yilgor C, Cawley DT, Hayashi K, Alanay A, Kleinstueck FS, Pellise F, Perez-Grueso FJS, Jean-Marc V, Bourghli A, Acaroglu ER, and Obeid I
- Subjects
- Adult, Aged, Databases, Factual, Disability Evaluation, Female, Humans, Middle Aged, Retrospective Studies, Surveys and Questionnaires, Treatment Outcome, Quality of Life, Scoliosis diagnostic imaging, Scoliosis surgery
- Abstract
Purpose: To determine if responses given to each question of the Scoliosis Research Society-22 (SRS22), Oswestry disability index (ODI) and Short Form-36 (SF-36) questionnaires are influenced by the radiological parameters., Methods: Patients enrolled in a multi-centre prospectively collected adult spinal deformity database who had complete SRS22, ODI and SF-36 data at baseline and at one-year follow-up were analysed. The presence of a differential item function of each question within each score in relation to radiological parameters was analysed using a mixed Rasch model with the radiological threshold value(s) determined., Results: Of those patients analysed (n = 1745; 1406 female, average age 51.0 ± 19.8 years), 944 were surgically and 801 were non-surgically treated. For the SRS22, questions (Q) 3, 5 and 18 were sensitive to almost all radiological parameters and the overall score was found sensitive to the Cobb angle. For the ODI, Q3, 6, 9 and 10 were not sensitive to any radiologic parameters whereas Q4 and 5 were sensitive to most. In contrast, only 3 of the SF-36 items were sensitive to radiological parameters., Conclusions: 78% of the SRS-22, 60% of the ODI and 8% of the questions in the SF-36 are sensitive to radiological parameters. Sagittal imbalance is independently associated with a poor overall outcome, but affects mental status and function more than pain and self-image. The assembly of questions responsive to radiological parameters may be useful in establishing a connection between changes in radiologic parameters and HRQL., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2022
- Full Text
- View/download PDF
48. Radiographic outcomes and complications after L4 or L5 pedicle subtraction osteotomy for fixed sagittal malalignment in 102 adult spinal deformity patients with a minimum 2-year follow-up.
- Author
-
Bourghli A, Boissiere L, Chevillotte T, Huneidi M, Silvestre C, Abelin-Genevois K, Grobost P, Pizones J, Roussouly P, and Obeid I
- Subjects
- Adult, Follow-Up Studies, Humans, Lumbar Vertebrae diagnostic imaging, Lumbar Vertebrae surgery, Osteotomy adverse effects, Osteotomy methods, Postoperative Complications diagnostic imaging, Postoperative Complications epidemiology, Postoperative Complications etiology, Retrospective Studies, Treatment Outcome, Kyphosis complications, Kyphosis diagnostic imaging, Kyphosis surgery, Spinal Fusion adverse effects, Spinal Fusion methods
- Abstract
Purpose: The objective of this retrospective study was to provide the radiographic outcomes and complications for pedicle subtraction osteotomy (PSO) performed at the low lumbar spine, i.e., L4 or L5 for ASD patients with fixed sagittal malalignment., Methods: ASD patients who underwent L4 or L5 PSO with a minimum 2-year follow-up were included. Preoperative and postoperative radiographs, and complications were collected. Radiographic analysis included lumbar lordosis (LL), pelvic incidence (PI), pelvic tilt (PT), thoracic kyphosis (TK), sagittal vertical axis (SVA), spinal lordosis (SL) ratio and global tilt (GT) on standing long-cassette radiographs., Results: A total of 102 patients from 2 spinal centers were analyzed. 66 patients underwent PSO at L4 and 36 patients at L5. From preoperatively to the final follow-up, significant improvements occurred in LL (from - 31° to - 52°), SVA (from 13 to 5 cm), and GT (from 44° to 27°) (all, p < 0.05). 12 patients had transient neurological deficits, and 8 patients had persistent neurological deficit. 23 patients underwent revision for PJK (2), pseudarthrosis (10), neurological deficit (2), epidural hematoma (1), or deep surgical site infection (8). No PJK was observed in any of the patients with L5 PSO., Conclusions: PSO at the level of L4 or L5 remains a challenging technique but with an acceptable rate of complications and revisions. It enables correction of fixed sagittal malalignment in ASD patients with a globally satisfactory outcome. In comparison with L4 PSO, L5 PSO patients did not show PJK as a mechanical complication. Distal lumbar PSO at the level of L5 may represent one of the factors that may help preventing the proximal junctional kyphosis complication., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2022
- Full Text
- View/download PDF
49. Treatment of lumbar canal stenosis in patients with compensated sagittal balance.
- Author
-
Mohsinaly Y, Boissiere L, Maillot C, Pesenti S, and Le Huec JC
- Subjects
- Constriction, Pathologic etiology, Constriction, Pathologic surgery, Decompression, Surgical methods, Humans, Lumbar Vertebrae diagnostic imaging, Lumbar Vertebrae surgery, Retrospective Studies, Treatment Outcome, Spinal Fusion methods, Spinal Stenosis complications, Spinal Stenosis diagnostic imaging, Spinal Stenosis surgery
- Abstract
Introduction: The need to combine fusion with decompression in patients with lumbar canal stenosis is still controversial. The aim of this study was to show that isolated decompression leads to the same outcomes as decompression plus fusion in patients who have preserved global sagittal balance., Materials and Methods: A single-center retrospective cohort of 110 patients who were operated for a single-level lumbar stenosis was divided into two groups based on the treatment: isolated decompression or fusion-decompression. These patients had a normal odontoid-hip axis angle (ODHA) (-5° to +2°) and had no spondylolisthesis or frontal deformity. We compared the clinical outcome scores and spinal-pelvic parameters preoperatively and at 1 year of follow-up. We evaluated the minimal clinically important difference (MCID) corresponding to a 12.8-point difference in the Owestry Disability Index (ODI). The analysis in each group was based on the MCID., Results: The clinical outcome scores improved significantly in both groups. There was a 77% decrease in the ODI>12.8 points with no significant difference between groups. The analysis based on the MCID showed that patients with a poor clinical result at 1 year in the isolated decompression group were more likely to have lumbar pain, while the ones in the fusion-decompression group were more likely to have radicular pain., Conclusion: The clinical and radiological results of fusion-decompression are not superior at 1 year relative to isolated decompression for treating single-level lumbar canal stenosis in patients with compensated sagittal balance. Full-spine weight bearing radiographs are key to determining the patient's sagittal balance and to ensuring there are no radiological instability factors that may require a stabilizing procedure., Level of Evidence: IV Retrospective study of data collected prospectively., (Copyright © 2021 Elsevier Masson SAS. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
50. Pseudarthrosis in adult spine deformity surgery: risk factors and treatment options.
- Author
-
Marques MF, Fiere V, Obeid I, Charles YP, El-Youssef K, Lahoud A, Faddoul J, Ferrero E, Riouallon G, Silvestre C, Le Huec JC, Kieser D, and Boissiere L
- Subjects
- Adult, Humans, Quality of Life, Retrospective Studies, Risk Factors, Treatment Outcome, Pseudarthrosis etiology, Pseudarthrosis surgery, Spinal Fusion adverse effects
- Abstract
Purpose: Highlight risk factors for pseudarthrosis in long-segment spinal fusions, collect the approaches carried to address this complication., Methods: Patients with ASD and fusion of ≥ 4 levels with minimum follow-up (FU) of ≥ 2 years were included. Full-body X-rays were done preoperatively, < 3 months and ≥ 2 years. Oswestry disability index (ODI), Scoliosis Research Society-22 and SF36 assessed pre- and postoperatively. The relationship between demographic, surgical and radiological variables with the development of pseudarthrosis was evaluated., Results: Out of 524 patients included, 65 patients (12.4%) developed pseudarthrosis and 53 underwent revision surgery. Notably, 88% of pseudarthrosis cases are associated with fusion length (OR = 1.17, 95% CI = 1.05-1.292, p = 0.004), osteotomy requirement (OR = 0.28, 95% CI = 0.09-0.85, p = 0.025), pelvic fixation (OR = 0.34, 95% CI = 0.13-0.88, p = 0.026) and combined approaches (OR = 3.29, 95% CI = 1.09-9.91, p = 0.034). Sagittal alignment is not related to the rate of pseudarthrosis. Health related and quality of life scores were comparable at last FU between patients revised for pseudarthrosis and those that didn't require revision surgery (ODI = 28% no revision and 30% revision group)., Conclusions: Pseudarthrosis is not related to malalignment, but with the surgical techniques employed for its treatment. Anterior approaches with anterior support decrease the rate by 30%, while long fusions, osteotomies and pelvic fixation increase its rate., (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature.)
- Published
- 2021
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.