61 results on '"L Koepke"'
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2. Cardiac implantable electronic devices and outcomes in heart failure patients with syncope
- Author
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P Rattanawong, C Chao, A Sriramoju, M Tagle-Cornell, J Farina, E Beirne, L Koepke, O Fatunde, N Ko Ko, A Shanbhag, T Barry, and W K Shen
- Subjects
Physiology (medical) ,Cardiology and Cardiovascular Medicine - Abstract
Funding Acknowledgements Type of funding sources: Private hospital(s). Main funding source(s): Mayo Clinic Background/Introduction Syncope is a common presentation in heart failure (HF) patients. However, the associations between syncope and prognosis in HF patients with the cardiac implantable electronic device (CIED) have not been demonstrated. It is unclear whether syncope increases all-cause mortality in HF patients with CIED. Purpose We aimed to examine the association between syncope and all-cause mortality in the largest cohort of HF with reduced ejection fraction (HFrEF), mid-ranged ejection fraction (HFmEF), and preserved ejection fraction (HFpEF) patients with and without CIED. Methods A retrospective cohort of patients with HF and syncope at our hospital between 2010 and 2015 were identified, and 1:1 propensity was matched with a control group of HF patients without syncope. A chart review was conducted. The multivariate Cox regression model was applied to estimate the association between syncope and the all-cause mortality endpoint. Results 3,449 HF patients were diagnosed with syncope (mean age, 72.8±14.5 years; 41.5% women), and the propensity-matched control HF patients without syncope (n=3,449) aged 72.8±14.3 years, and 42.5% women were selected. Cardiac implantable electronic devices were implanted more in HF patients with syncope (32.5% versus 13.7%, p Conclusions Syncope significantly increased the risk of all-cause mortality in HFrEF patients but not in HFmEF or HFpEF patients with CIED. The association of syncope and increased mortality in HFrEF patients with CIED suggests that syncope may be a marker and a factor of mortality and warrants further investigation.
- Published
- 2023
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3. Responses in vegetative selection and diet quality for dissimilar sheep breeds under targeted grazing of yellow sweetclover
- Author
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John Derek Scasta, Whit C Stewart, and Kalli L. Koepke
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biology ,Antilocapra americana ,Forage ,biology.organism_classification ,Breed ,Animal science ,Fodder ,Melilotus officinalis ,Wool ,biology.animal ,Grazing ,Animal Science and Zoology ,Ovis ,Food Science - Abstract
Objective Sheep are advantageous for targeting invasive plants; however, nutritional consequences of such projects are poorly understood. Genetically dissimilar sheep breeds, or pronghorn (Antilocapra americana) browsing, were assessed to determine selectivity of sweetclover (Melilotus officinalis) and sheep dietary quality. Materials and Methods In 2015 and 2016, 24 ewes and lambs and 21 ewes and lambs (per breed group annually; Ovis aries; Rambouillet or Hampshire breeds) were grazed in four 3.2-ha paddocks for 16.5-d (±8 d) grazing bouts. Vegetation and sheep diet quality (using near-infrared reflectance spectroscopy of fecal material) were analyzed relative to sheep breed and timing, or pronghorn only. Results and Discussion Vegetation responses were never different by sheep breed (P ≤ 0.05); meat and wool breeds similarly reduced sweetclover abundance, proportion of aerial stems and flowering stems, and height more than pronghorn only (all P Implications and Applications Both meat and wool breeds may be effective for targeted grazing, but different breeds may have different diet quality due to differential grazing behaviors and N synthesis and retention.
- Published
- 2019
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4. Search for Higgs andZBoson Decays toϕγwith the ATLAS Detector
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E. Ros, IS Castillo, Giada Mancini, S. Youssef, Almut Pingel, Remco Castelijn, D. P. C. Sankey, Michal Simon, Tetsuo Kishimoto, Steinar Stapnes, Ludovico Pontecorvo, Pedro Urrejola, Diedi Hu, Tommaso Colombo, S. H. Robertson, B. G. Pope, C. J. S. Young, Masato Aoki, Wallangen, Xuai Zhuang, Samira Hassani, Kirill Grevtsov, C. Da Via, Daniel Lellouch, Alfred Goshaw, Stefanie Adomeit, Kartvelishvili, Josh Moss, Enrique Kajomovitz, K. Potamianos, David-leon Pohl, Evgenii Baldin, Louis Helary, Yiming Abulaiti, Martin Zeman, Anna Mastroberardino, Cac Barajas, Robert Kehoe, Bruno Lenzi, Nathan Peter Readioff, Amanda Cooper-Sarkar, Peter Wienemann, Yasuo Minami, S. De Cecco, Daniel Bullock, James Robinson, Ole Røhne, Adi Ashkenazi, Frank Siegert, K.-H. Becker, Petre Dita, Mateusz Dyndal, Andrzej Olszewski, Antonio Ereditato, Harinder Singh Bawa, Oliver Kortner, Nikolaos Konstantinidis, Sebastian Mergelmeyer, Judith Katzy, Felix Buehrer, Roman Lysak, Christoph Eckardt, D. Amidei, Nicholas Adam Styles, Federico Meloni, Carolyn Bertsche, A. Rodriguez Perez, Javier Montejo Berlingen, Shuwei Ye, Takehiko Mori, Per Edvin Sidebo, Alberto Aloisio, Yaquan Fang, Kirill Prokofiev, N. De Groot, Kristian Gregersen, Jon Kerr Nilsen, L. Cerda Alberich, Herget, Edoardo Maria Farina, Fernando Barreiro, Itamar Roth, Tomas Kosek, Lorenzo Massa, Adam Trzupek, Andrea Catinaccio, W. Iwanski, J. A. Bogaerts, Sarah Kate Boutle, Xi Chen, Theodoros Alexopoulos, Dorian Simon, Brigitte Vachon, H. Zhu, H. Kagan, A. L. Yen, K. Ntekas, Domizia Orestano, Semen Turchikhin, Andrew Hard, Markus Cristinziani, Wolfgang Liebig, Elizaveta Shabalina, Din Villar, Thomas Trefzger, Elliot Hughes, Daniel Scheirich, Martin Tripiana, Avi Gershon, A. Salamon, Richard Bates, Ossama AbouZeid, Phillip George Hamnett, T. N. Manh, Martin Rybar, Marko Mikuz, Lillian Smestad, Hans Peter Beck, Manuel Patrice Geisler, Khovanskiy, Timothy Andeen, Andrey Minaenko, Andrei Salnikov, G. Mc Goldrick, Tancredi Carli, Roberto Cardarelli, Beatrice Mandelli, Roland Jansky, Ask Emil Loevschall-Jensen, Felix Socher, Cecilia Taccini, James Shank, Christian Weiser, Andrew Washbrook, Emilio Higón-Rodriguez, Christopher Bock, Kevin Black, Anne Marie Sickles, Kevin Daniel Finelli, William Keaton Balunas, Ashutosh Kotwal, Renat Sadykov, Rudiger Voss, David Martin Bjergaard, Alexander Bogdanchikov, Marco Vanadia, Koichi Nagai, M. J. Da Cunha Sargedas De Sousa, Andrey Soukharev, Nacim Haddad, Francesco Guescini, Nan Lu, S. Timoshenko, Helena Santos, Ricardo Neves, Timon Heim, D. Rodriguez Rodriguez, Bertrand Laforge, Jeffrey Wayne Hetherly, Thomas Ravenscroft, Paolo Laurelli, Barbara Liberti, James Pinfold, E. P. Le Quilleuc, A. S. Thompson, Alexey Zhemchugov, Huan Ren, Markus Nordberg, J. Chudoba, Igor Mandić, Yongke Zhao, Andrew Chisholm, Matteo Bauce, Maria Curatolo, Fjm Sanchez, J. N. Butler, Anyes Taffard, Jiri Hejbal, Vadim Bednyakov, Wdb Madden, Fabian-Phillipp Tepel, Laurelle Maria Veloce, Ryuichi Takashima, Andreas Alexander Maier, Simon Schmitz, Oxana Smirnova, T. Todorov, Konstantinos Bachas, Givi Sekhniaidze, Juraj Smiesko, A. Di Simone, Francesco Ragusa, Bruno Galhardo, Jan Schaeffer, Zhenwei Yang, P. Malecki, Ning Zhou, C. H. Chen, Andrey Sapronov, Nicolas Berger, S. P. Amor Dos Santos, Paul Mircea Gravila, Lydia Brenner, Borut Paul Kerševan, Claudia Giuliani, E. S. Kuwertz, Tomas Dado, Benedetto Giacobbe, Andrea Messina, Tulay Cuhadar Donszelmann, Aidan Robson, Ioannis Gkialas, Joachim Heinrich, Takashi Kubota, Tudorache, Simone Amoroso, Pleskot, Michael Ernst, Raphael Vuillermet, John Morris, Steffen Maeland, Stefan Wolf Weber, Malte Backhaus, Claudia Glasman, Pascal Pralavorio, Lamberto Luminari, EV Santurio, Yoshiji Yasu, A. Andreazza, Yoram Rozen, F. Luehring, E. Piccaro, Brinick Simmons, Louise Heelan, James Pearce, Daniel Froidevaux, C. S. Rogan, Davide Melini, James Mueller, Peter Loch, S. Argyropoulos, P. Giromini, Jan Kretzschmar, Margret Fincke-Keeler, Susan Cheatham, F. Salvatore, Torsten Harenberg, Oliver Chris Endner, Giulio Tiziano Forcolin, Andrew Stuart Bell, Andreas Wildauer, Reina Camacho Toro, Ippolito, S. P. Y. Yuen, Patrick Bryant, Bensinger, Miriam Diamond, Fernando Monticelli, Elena Yatsenko, Salvatore Tupputi, Maciej Trzebinski, G. Cortiana, Marcello Bindi, Peter Krieger, Lluisa-Maria Mir, Ryan Reece, Mauro Dell'Orso, Hermann Kolanoski, Castillo Gimenez, Matthias Schott, Dimitrios Kyriazopoulos, Oleh Kivernyk, Maximilian Swiatlowski, C. Haber, Hai Jiang, Flera Rizatdinova, H. Ghazlane, Junichi Kanzaki, Sabrina Perrella, Joao Seixas, Moritz Kretz, Maddalena Giulini, Horst Oberlack, Veysi Erkcan Ozcan, Katherine Pachal, James Monk, Sarah Louise Barnes, Gabriella Sciolla, Andreas Christian Dudder, S. Albrand, Morisbak, Petr Tas, S. H. Oh, Laura Gonella, J-B Blanchard, Jessica Liebal, Alan Poppleton, Stefano Veneziano, ET Pastor, Nicolas Ellis, Andre Schoening, Fabio Cerutti, Naoki Ishijima, Sascha Caron, G. T. Jones, Juan Pedro Ochoa-Ricoux, Mika Huhtinen, Julien Maurer, James Broughton, Julien Donini, Christophe Royon, Vladimir Sulin, John Derek Chapman, W. Kozanecki, J. E. Brau, A. Lanza, Sigve Haug, Christopher Bee, Petr Vokac, M. King, Joern Grosse-Knetter, Sanda Dita, Yao Ming, Oleg Brandt, Angelantonio Castelli, Allison McCarn, Yichen Li, D. Gillberg, David Olivier Jamin, K. Kordas, Rupert Leitner, Louis Fayard, Benoit Lefebvre, James Ferrando, Ruo-yu Shang, Attila Krasznahorkay, Bernardo Sotto-Maior Peralva, Fabio Cardillo, S. Sun, Alexander Fenyuk, Luigi Vigani, Maurizio Piccinini, Marcella Capua, Peter Jenni, Miguel Arratia, Fengwangdong Zhang, Julius Hrivnac, T. Wang, Eleni Mountricha, Didier Lacour, Ondrej Penc, M. P. Giordani, Ricardo Abreu, Adriana Milic, Sandra Kortner, M. I. Martínez, Alexey Kharlamov, Vadim Kostyukhin, Lars Graber, Giuseppe Francesco Tartarelli, Sergio Grancagnolo, Miriam Watson, A. T. H. Arce, Edward Diehl, Konstantinos Nikolopoulos, Puja Saha, Petter Nilsson, Andrew D. Hamilton, Arthur James Horton, R. S. Orr, Brian Cole, Daniel Mori, F. M. Giorgi, S. P. Mc Kee, Lorenzo Paolozzi, S. Heim, Reisaburo Tanaka, Livio Mapelli, Makoto Hasegawa, Guido Volpi, J. A. Wilson, Tomas Slavicek, Manuella Vincter, Yoichi Ninomiya, Anna Lipniacka, Romain Madar, M. Moreno Llácer, Cavasinni, Guennadi Borissov, Jbdv De Regie, Stephen Burke, Stéphane Viel, Michele Bianco, Francesco Cirotto, M. J. Oreglia, Geoffrey Gilles, Vrba, Shigeru Odaka, Sebastien Prince, A. Tavares Delgado, Ana Cueto, Stephen Philip Marsden, Igor Potrap, Pavlos Ioannou, Cedric Serfon, Nicola Semprini-Cesari, M. Garcia-Sciveres, Yu Nakahama, Nabila Wahab Shaikh, Marcel Michael Stanitzki, Junji Tojo, Benjamin Sowden, Dirk Zerwas, Glenn Amundsen, Martin White, Eric Feng, Carsten Daniel Burgard, Sahal Yacoob, Aaj Lesage, Konstantin Belotskiy, Oleg Solovyanov, Vim Outschoorn, Ulrike Schnoor, Kristof Schmieden, Davide Costanzo, J-P. Meyer, Werner, Lucio Cerrito, Peng Huo, MV Perez, Marie Christine Lanfermann, A. A. Nepomuceno, Liaoshan Shi, P. Lichard, Tomo Lazovich, Luc Goossens, Stefanos Leontsinis, Francesco Lacava, Thomas Beermann, Athanasios Petridis, Ivan Yeletskikh, J. T. P. Burr, Jain, Alberto Mengarelli, A. Sanchez, P. D. Thompson, Michael Bender, Sergey Burdin, Dmitry Emeliyanov, Yasuhiro Makida, Y. C. Zhu, Paolo Camarri, Stefan Tapprogge, Sanchez Martinez, Pawel Klimek, Smakhtin, H. Lu, Mdmc Garrido, Aleandro Nisati, J. Jimenez Pena, Steve McMahon, Daniela Rebuzzi, Till Eifert, R. K. Daya-Ishmukhametova, Itsuo Nakano, Timothy Michael Bristow, Harald Fox, Lashkar Kashif, Hendrik Esch, P. J. Clark, Edmund Dawe, Alexandra Tudorache, Paolo Dondero, Takahiro Fusayasu, I. Ravinovich, Kerstin Lantzsch, Antonio Parodi, Sophio Pataraia, Ladislav Chytka, Wardrope, Jonathan Long, Heather Russell, Andrew Pilkington, Jean-Francois Laporte, Lidia Dell'Asta, Fabrice Hubaut, Dmitriy Maximov, J. H. N. Rosten, W. C. Fisher, Aziz Chafaq, Giulia Ucchielli, M. Tanaka, Y. Benhammou, Juansher Jejelava, Evgueni Ladygin, Keisuke Yoshihara, Ruiqi Zhang, Mab do Vale, Miroslav Hrabovsky, Yee Chinn Yap, Kazunori Hanagaki, Yuji Enari, Iurii Naryshkin, Magdalena Slawinska, Alexey Anisenkov, Nikita Belyaev, G. Duckeck, R. Di Nardo, Jana Faltova, Federica Legger, Stanislav Pospisil, Antonia Strubig, Clara Troncon, Masaharu Nomachi, Markus Zinser, Robert Keyes, David DeMarco, Massimiliano Bellomo, Silvia Miglioranzi, Aranzazu Ruiz-Martinez, Bradley Daniel Schoenrock, James Lacey, D. Di Valentino, Simon Stark Mortensen, Xuanhong Lou, Kathryn Grimm, Nikolai Marcel Hartmann, M. Morii, Stefan Gadatsch, Simone Michele Mazza, H. Namasivayam, M. Marx, P. de Jong, Christopher Samuel Pollard, Claudio Luci, Fabian Kuger, W. Fedorko, Sergey Kuleshov, I. V. Gorelov, Nils Flaschel, Tovey, Klaus Moenig, Artem Basalaev, Kamil Augsten, Joseph Stanford Ennis, Stephen Maxfield, Yanwen Wu, Gianluca Introzzi, Sabine Lammers, Ruth Laura Sandbach, Hilal Kucuk, Maria Elena Stramaglia, Roberto Iuppa, Efstathios Karentzos, Ivan Sykora, Abraham Seiden, Jgp Vazquez, Andrew Mehta, E. Graziani, Denys Denysiuk, I. M. Gregor, Tetsuro Mashimo, Luka Kanjir, L. Barranco Navarro, Y. Huang, Michael Flowerdew, B. Liu, Graham Savage, Consorti, Shota Tsiskaridze, Reyhaneh Rezvani, Evgeniya Cheremushkina, Simon Lin, Reiner Hauser, Bruce Gallop, Manuel Neumann, Martin Spangenberg, Giuseppe Avolio, C. T. Potter, Dengfeng Zhang, Aaron Angerami, Alejandro Alonso, Giovanna Cottin, Lars Beemster, Markus Elsing, Lee Sawyer, Leszek Adamczyk, Driss Benchekroun, Kunihiro Nagano, Sutton, Lawrence Lee, Andrea Knue, NL Martinez, Steffen Henkelmann, Tobias Heck, P. Farthouat, Maurice Becker, Bruce Barnett, E. Rizvi, Eduard Simioni, P. H. Hansen, Osamu Jinnouchi, Stanislav Nemecek, Stefan Rave, Massimo Corradi, Mario Lassnig, A. Maio, K. K. Temming, A. Di Ciaccio, Asma Hadef, Nathan Rogers Bernard, Driss Goujdami, Beate Heinemann, W. Van Den Wollenberg, U. De Sanctis, Ralph Schaefer, ST Araya, A. Gomes, Haleh Khani Hadavand, Daniel Pluth, Yousuke Kataoka, E. B. F. G. Knoops, Paolo Mastrandrea, A. Borisov, Mark Stockton, Yoichi Ikegami, Marco Battaglia, L. La Rotonda, Jam Quijada, Mauro Citterio, Guillermo Nicolas Hamity, Alessandro Calandri, Lydia Iconomidou-Fayard, Emmerich Kneringer, Martin Johannes Schultens, Donatella Cavalli, U. Mallik, C. A. Lee, T. Kono, Nils Ruthmann, Vassili Kazanin, Oleg Bulekov, Samina Jabbar, Ivana Hristova, Edisher Tskhadadze, Jorge Duarte-Campderros, Sebastien Binet, Christoph Amelung, F. G. Oakham, Mirkoantonio Casolino, Igor Gavrilenko, Chiarella, Yorihito Sugaya, B. Di Micco, Adam Jinaru, H. S. Chen, Antonio Limosani, Tsulaia, C. Belanger-Champagne, Raymond Brock, G. Sauvage, Giovanni Crosetti, Stefania Antonia Stucci, Giovanna Bruni, William Joseph Johnson, Ph. Schune, W-M. Yao, Dominique Pallin, Seyed Ruhollah Shojaii, Marco Rimoldi, Antoine Marzin, Batley, Gen Kawamura, Wim Lavrijsen, Enrico Pasqualucci, Roberto Ferrari, R. Ishmukhametov, Anna Sfyrla, T. Theveneaux-Pelzer, F. Lo Sterzo, Matthew Gignac, Samuel Joseph Crawley, Paola Giannetti, L Koepke, Ayda Beddall, Andrea Gaudiello, Daniel Dobos, Yoshinobu Unno, Rfn Garcia, Andrej Gorišek, P. Fernandez Martinez, Francesco Rubbo, Y. M. Ma, Craig Blocker, Gregor Herten, Francis Anghinolfi, Kerim Suruliz, Nikolaos Karastathis, Monika Wielers, C. F. Feng, Frank Filthaut, Adam Edward Barton, Anne-Isabelle Etienvre, Francesco Conventi, Maximilian Goblirsch-Kolb, Gabriele Bertoli, Faten Hariri, Gideon Bella, Victor Sorin Martoiu, Bmm Allbrooke, Petr Balek, D. Fassouliotis, H. J. Burckhart, Konstantin Toms, Peter Berta, Manuela Venturi, Babar Ali, Timothy Brooks, J. Hays, Robert Gardner, M. A. Thomson, Martin Spousta, Morad Aaboud, Christoph Falk Anders, Naim Bora Atlay, Oleksandr Viazlo, Adam Jackson Parker, Akshay Katre, Andreas Hoecker, Thijs Cornelissen, Benjamin Henry Hooberman, Liron Barak, B. K. B. Chow, Stefano Rosati, Marco Filipuzzi, Giora Mikenberg, Eric Lancon, Sopko, Mohamed Ouchrif, Juraj Bracinik, Clara Nellist, Christos Gentsos, J. P. Thomas, Chiara Rizzi, Pater, Dusan Bruncko, Marco Bruschi, Baojia Tong, Andrew Gerard Leister, Corrinne Mills, Jason Veatch, Chris Hays, J. Urban, Sami Kama, Serena Palazzo, Christopher Willis, Manuela Campanelli, Sophie Trincaz-Duvoid, Kazuhiko Hara, Martin Florian Bessner, Irina Antonela Cioara, Emily Nurse, Amh Correia, Julia Isabell Djuvsland, Revital Kopeliansky, Elizabeth Gallas, Elena Plotnikova, A. J. Lankford, Maike Christina Hansen, E. K. U. Gross, Göran Jarlskog, Emily Marie Duffield, Andrew Karamaoun, Polina Nechaeva, Harshna Jivan, Federico Bertolucci, Robert J. Bielski, P. A. Delsart, Olga Beltramello, Nicoletta Garelli, Michael R. Wessels, German D Carrillo-Montoya, A. De Santo, T. Del Prete, John Rutherfoord, Jun Su, Harald Joerg Stelzer, Bobby Samir Acharya, H. A. Neal, Andrey Ryzhov, Guillaume Unal, A. Artamonov, K. G. Tan, Othmane Rifki, Daniela Bortoletto, Nello Bruscino, Pavel Reznicek, Evgeny Starchenko, Abner Soffer, Pienpen Seema, Toshiaki Kaji, B. M. Waugh, Claire Antel, Sylvestre Pires, Charles Leggett, Marco Schioppa, Nicola Orlando, Yangyang Cheng, Andrea Bocci, Chiara Meroni, M. P. J. Landon, Bruce Yabsley, C. Padilla Aranda, Clark, B. Sarrazin, Massimo Antonelli, Paul Jackson, Ozan Arslan, G. Usai, Patrick Puzo, Alessandra Camplani, C. Lapoire, Daniela Salvatore, Rebecca Jane Falla, H. Zhang, Tomas Sykora, Valery Schegelsky, Sabrina Groh, Wendy Taylor, Fumiaki Ito, Ralf Hertenberger, J. Van Nieuwkoop, Kus, Steffen Stärz, Michael Shupe, J. Beringer, Kerstin Tackmann, Olga Novgorodova, D. Su, Smr Saez, Andrea Favareto, William Quayle, Joe Taenzer, Yang Yang, A. Ferrer, Masaki Ishitsuka, Serge Smirnov, Bengt Lund-Jensen, Stefano Camarda, Stefano Terzo, Michael Hance, A. J. Barr, Tingting Cao, K Kentaro, Marc Escalier, Alyssa Montalbano, Yang Gao, Elliott Cheu, Diane Cinca, Elzbieta Banas, T. J. Neep, Reiner Klingenberg, Helmut Wolters, Johanna Gramling, MF Giannelli, Massimo Lazzaroni, Brian Lee Clark, Alexandra Schulte, John Huth, LM de Andrade Filho, Shuyang Hu, Catherine Hsu, Mihai Ciubancan, Oliver Ricken, Jelena Krstic, N. Benekos, Halina Abramowicz, Yuriy Ilchenko, Ksenia Gasnikova, Federico Scutti, Fabian Huegging, J. Wetter, A. M. Zaitsev, Rute Pedro, Lorenz Hauswald, A. Firan, M. Cooke, Kyungeon Choi, Konstantinos Karakostas, E. J. W. Moyse, Stewart Martin-Haugh, Karsten Koeneke, Daniel Whiteson, Elisa Guido, Peter Kluit, Jemal Khubua, Nataliia Kondrashova, Nimrod Taiblum, Alexey Boldyrev, Silje Raddum, Stephen Watts, J. E. Pilcher, Matteo Cavalli-Sforza, Stephen Hillier, Luis Hervas, D. Boscherini, Nikola Makovec, Tsiskaridze, Farida Fassi, S. Gadomski, Emilio Petrolo, M. zur Nedden, Marek Palka, F. K. Loebinger, Denis Salihagic, B. Jackson, M. Shimojima, Geoffrey Henry Herbert, G. Susinno, Bradley Cox, Joe Kroll, Eda Yildirim, Jonathan Butterworth, Marcella Bona, Sergey Chekulaev, Kohei Yorita, Cristinel Diaconu, O. Cakir, Benjamin Bordy Tannenwald, G. Carlino, Radeka, Aldo Saavedra, Atsuhiko Ochi, Hernan Reisin, Poj Gradin, Elizabeth Brost, J. Griffiths, Paolo Iengo, Rachel Rosten, Julia Fischer, E. L. Barberio, Katharina Bianca Jakobi, Naoki Kimura, Judita Mamuzic, James Howarth, Michal Vlasak, Lily Asquith, F. S. Merritt, Marco Milesi, D. M. Seliverstov, Yasuyuki Okumura, O. Le Dortz, Liang Li, Christian Gutschow, Irakli Minashvili, Danuta Kisielewska, Carlo Schiavi, Allan G Clark, Roger Moore, Anna Macchiolo, Andree Robichaud-Veronneau, Bartlomiej Zabinski, Haykuhi Musheghyan, Weber, Andreas Redelbach, Sorin, Nathalie Besson, Farid Ould-Saada, Justas Zalieckas, Alevtina Shmeleva, Brian Le, Frederic Brochu, Ryszard Stroynowski, Davide Caforio, Yona Oren, B. Åsman, Oldrich Kepka, Francois Vazeille, Tina Sfiligoj, Y. Hernández Jiménez, Vladimir Peshekhonov, R. F. Y. Peters, Ryne Michael Carbone, Susumu Oda, Gabriel Palacino, Brm Garcia, Karel Smolek, Werner Wiedenmann, Lukas Plazak, Stephen Haywood, Elemer Nagy, Sotirios Vlachos, M. J. Alconada Verzini, E. Castaneda-Miranda, Alexi Gongadze, Katsuo Tokushuku, Sylvain Blunier, R. R. Debbe, Jason Dhia Mansour, Yuji Yamazaki, Lewis James Armitage, Darren Price, Fedor Prokoshin, Krzysztof Korcyl, Liyuan Han, Attilio Picazio, RC El Moursli, Thorsten Wengler, Stan Bentvelsen, J. C. Vermeulen, Lydia Beresford, Ilija Vukotic, James Beacham, Aleksandra Dimitrievska, Arno Straessner, Monica D'Onofrio, Alexander Undrus, A. Bruni, Ivor Fleck, Walter Lampl, O'Shea, Benedict Tobias Winter, C. Young, Catrin Bernius, F. Parodi, Jan Thomas Kuechler, Pierre Savard, Paul Fraser Harrison, Laurent Vacavant, Carter, Giancarlo Spigo, Kathleen Whalen, David Freeborn, Evelyn Thomson, Matteo Bedognetti, Valerie Susanne Lang, Nikola Lazar Whallon, Johannes Elmsheuser, Klaudia Burka, Alessandra Baas, Sergey Peleganchuk, Saverio D'Auria, Douglas Schaefer, Alex Martyniuk, Wolfgang Wagner, Marie-Hélène Genest, Matteo Franchini, Armin Michael Nairz, S. D. Worm, Oliver Stelzer-Chilton, Matthias Klein, Alexey Talyshev, E. Jansen, Fred Hartjes, R. Santonico, C. Sanchez, Giosuè Costa, Bradley Axen, Pierre-Hugues Beauchemin, Aaron James Armbruster, Oliver James Winston, Yongsun Kim, Elisabeth Schopf, S. Todorova-Nova, Shaun Gupta, Olga Igonkina, Alberto Cervelli, Giovanni Darbo, EP Codina, Marianna Testa, Daniele Zanzi, Theodota Lagouri, AL Solis, C. Di Donato, Jacquelyn Brosamer, David William Casper, Graeme Stewart, Lorenzo Bianchini, Bortolotto, Ludovica Aperio Bella, Mattias Ellert, M. Losada, Matthew Craig Mondragon, Giorgi Arabidze, Andreas Warburton, P. M. Tuts, Shu Li, D. V. Dedovich, Florian Bauer, Samuel Webb, Hoffmann, Dimitriy Krasnopevtsev, G. Calderini, Carmen García, Kerry Ann Parker, Hyungsuk Son, B. A. Long, Giuseppe Iacobucci, Thomas Koffas, James Walder, Yang Heng, Andrew John Turvey, Paul Miyagawa, A. C. König, S. Cabrera Urbán, B. H. Brunt, David Cameron, Djamel Eddine Boumediene, K. P. Mistry, William Brooks, S. 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Suzuki, Stylianos Angelidakis, Janusz Chwastowski, Keith Zengel, Mark Slater, Andrew Nelson, John Alison, Gianluca Alimonti, Rainer Stamen, T. Schwindt, Iro Koletsou, Kilian Rosbach, Sara Valentinetti, Tohru Takeshita, Iskander Ibragimov, R. Cantrill, Vladimir Tikhomirov, G. Hughes, Christos Anastopoulos, Bianca Osculati, Zinonas Zinonos, Ioulian Budagov, Makoto Tomoto, David H. Adams, Yahya Tayalati, E. Hines, Silvia Resconi, Mazuza Ghneimat, Tim Adye, Ewa Stanecka, W. K. Di Clemente, U. Soldevila, Jörgen Sjölin, Andre Sopczak, Zoya Karpova, Ki Lie, Fumihiko Ukegawa, Francesca Ungaro, Christopher Potter, R. D. Kass, Jacob Julian Kempster, Tony Liss, Nansi Andari, Lianyou Shan, Gian Luigi Alberghi, Rudolph, Richard Nisius, Jonathan Bortfeldt, Hantao Ji, Yosuke Takubo, David Berge, J. A. Aguilar-Saavedra, Melissa Ridel, Zdenek Hubacek, Giorgio Chiarelli, Lingshan Xu, S. J. Chen, Wen Guan, Uwe Bratzler, Anna Goussiou, Petr Gallus, Elisabetta Pianori, Y. Komori, Carl Gwilliam, D. M. 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Bos, Konstantinos Papageorgiou, V. R. Lacuesta, S. Passaggio, Luiz Caloba, Henric George Wilkens, Stefano Manzoni, Elisabeth Petit, Peyton Rose, Baptiste Abeloos, C-Q. Li, Michel Lefebvre, Emma Ideal, Edson Carquin, Gabriele Chiodini, S. Willocq, Marco Fraternali, Thibault Guillemin, Umar Gul, Catmore, Trygve Buanes, Lucie Gauthier, J. Tanaka, S. Kaneti, D. Levin, E. von Toerne, Julien Caudron, Luca Colasurdo, Chase Owen Shimmin, M. Stanescu-Bellu, Ian Brock, Sebastien Jonathan Kahn, Rachid Mazini, R. Kowalewski, Lukasz Zwalinski, Mengqing Wu, Moritz Backes, Sofia Chouridou, Sheena Schier, Peter Kodys, SC Lopez, M. C. N. Fiolhais, Armen Vartapetian, Maria-Teresa Dova, Grygorii Sokhrannyi, Uta Klein, Maria Smizanska, Silvia Biondi, Peter Buchholz, J. L. La Rosa Navarro, Fabrice Balli, Zdenek Dolezal, Henrik Akerstedt, Izzo, Abdeslam Hoummada, Georges Aad, J. Zhong, OB Bylund, Gabriella Pasztor, Michel Raymond, Bruce Schumm, PC Muino, Leonardo Merola, A. Hasib, Will Davey, M. C. van Woerden, Maria Giulia Ratti, A. Pacheco Pages, Hidetoshi Otono, Laura Jeanty, Christian Farina, Uladzimir Kruchonak, Gideon Alexander, R. W. L. Jones, Cristian Stanescu, Ovsat Abdinov, Hedberg, K. Nakamura, Dmitri Tsybychev, R. L. McCarthy, Dai Kobayashi, Thomas LeCompte, S. Hanisch, Metin Arik, Carmen Maidantchik, Dimitrios Iliadis, Polychronakos, Nora Emilia Pettersson, A. Korn, Sabrina Sacerdoti, C. P. Ward, B. Di Girolamo, Tamsin Nooney, Ewan Hill, Sune Jakobsen, Giacomo Artoni, Jessica Metcalfe, S. Yamamoto, Sabine Crépé-Renaudin, Margherita Spalla, Patrick Rieck, Stefania Spagnolo, Daniel Muenstermann, I. Massa, A. Soloshenko, Alexander Ruschke, Reinhard Schwienhorst, Michael A. Strauss, Andrey Kiryunin, Peter Nemethy, J. Schwindling, Olivier Arnaez, Elliot Lipeles, Saleh Sultansoy, Antonio Salvucci, Keita Hanawa, Stephen Jiggins, Hannah Arnold, Ehud Duchovni, Maximiliano Sioli, Marco Delmastro, Fridolin Dittus, Fionnbarr O'grady, Agni Bethani, Miao Liu, Tatjana Agatonovic-Jovin, G. H. A. Viehhauser, Tomas Davidek, Sandrine Laplace, Fabian Spettel, G. Anders, Theresa Obermann, Matthias Saimpert, Artur Trofymov, Michael Düren, Bmd Latour, Ina Carli, Peter Schacht, Tobias Golling, T. Scanlon, Callum Robert Kilby, Peter Sherwood, Pavel Starovoitov, Savanna Marie Shaw, Bernhard Meirose, John Penwell, Matevz Cerv, FL Manghi, J. A. Ernst, Soren Stamm, Dimitris Varouchas, Manolis Dris, J. M. Yu, Christian Heinz, Antonio Sidoti, Ian Hinchliffe, Antonio Boveia, Juergen Kroseberg, A. T. Doyle, Douglas Benjamin, Ryutaro Monden, N. Giokaris, Nataliia Zakharchuk, Patrick Czodrowski, Shikma Bressler, Wouter Verkerke, Priscilla Pani, Rhys Edward Owen, Satoshi Tanaka, Torre Wenaus, Dominic Hirschbuehl, Srinivasan Rajagopalan, Irene Vichou, Hal Evans, Vacek, Junpei Maeda, Orel Gueta, Artem Maevskiy, Adrian John Bevan, Loan Truong, Michael Solar, Andre Zibell, Are Strandlie, J. Albert, Russell Smith, Andrew Brandt, Fernando Marroquim, Frank Seifert, Li Zhou, M. Wittgen, Manfredi Ronzani, Zineb Idrissi, Fabien Jeanneau, Luca Fiorini, Merve Sahinsoy, Daniel Britzger, Jan Godlewski, Mariya Shiyakova, Danilo Giugni, Otmar Biebel, Vorobel, Takuya Nobe, Sebastian Nowak, Orjan Dale, Jelena Jovicevic, Gerjan Bobbink, Marisilvia Donadelli, Darren Temple, Dugan O'Neil, Robert Astalos, Emmanuel Monnier, Kathy Pommès, Mark Owen, Andrew Christopher Daniells, Nuno Filipe Castro, Haifeng Li, Dario Barberis, Mykhailo Lisovyi, Arnaud Ferrari, Laura Rehnisch, Dan Pantea, Tova Ray Holmes, Ljiljana Morvaj, Norbert Wermes, Marjorie Shapiro, Cristiano Alpigiani, Soshi Tsuno, S. L. Wu, Tony Kwan, T. Kawamoto, Sara Strandberg, Hartger Weits, Tracey Berry, Marco Aurelio Diaz, Tim Martin, Qiaoshi Zeng, Tai-Hua Lin, A. La Rosa, P. Sinervo, Remi Lafaye, N. L. Abraham, Radim Slovak, Cecile Deterre, Johannes Erdmann, Sara Ghasemi, Neubauer, Philippe Mermod, Michael Stoebe, Michel Vetterli, Heidi Sandaker, Sten Hellman, Jan Andre Stillings, Haolu Feng, Steve Muanza, Philip Sommer, B. Gibbard, Daiki Hayakawa, Dimitrios Sampsonidis, Robert Clarke, Christopher Unverdorben, Imma Riu, F. De Lorenzi, Branislav Ristic, Veeraraghavan, Alan Peyaud, Dorde Sijacki, Fabian Wilk, Bostjan Macek, R. St. Denis, Sally Seidel, Bing Zhou, Martin Kocian, Didier Ferrere, Odette Benary, Mihai Caprini, S. Donati, Trisha Farooque, Mikhail Levchenko, Alexander Paramonov, Marc Cano Bret, M. Franklin, Philippe Calfayan, P. van Gemmeren, Claudia Gemme, Michel Janus, Dirk Duschinger, Laurent Serin, Kaushik De, Benjamin Pearson, Peter Davison, Georgios Iakovidis, Daniela Boerner, Albert Olariu, Mikhail Demichev, Milind Purohit, A. Ezhilov, Rodger Mantifel, Libor Nozka, Rafal Staszewski, M. Della Pietra, Ping-Kun Teng, A. Onofre, Jan Stark, Konrad Kleinknecht, D. A. Soh, Ingo Bloch, L. A. M. Wiik-Fuchs, Henry Lubatti, Raquel Pezoa, S. Farrell, Teresa Barillari, Stefan Schmitt, Philipp Jonathan Lösel, Lidia Smirnova, Marine Kuna, Laurent Chevalier, Sp Griso, Sara Diglio, Tetiana Hryn'ova, Y. L. Chan, EF Torregrosa, Petr Hamal, Stefan Richter, A. De Maria, J. Boudreau, Z. Vykydal, Kerstin Jon-And, Yanjun Tu, J. Silva, Kiyotomo Kawagoe, Daniel Guest, Yulia Rodina, Giuseppe Lerner, Carl Jeske, Michael Ughetto, Milos Lokajicek, Karol Krizka, Sooraj Krishnan Radhakrishnan, Sophie Henrot-Versille, G. Compostella, Felix Mueller, A. J. Beddall, M. J. Kobel, Julian Bouffard, Mariusz Przybycien, Michael Andrew Parker, HD Yildiz, Marco Sessa, Shoji Asai, Claire Malone, Liang Guan, Thomas Lohse, R Stroehmer, Calin Alexa, Guido Gagliardi, Stephanie Majewski, Matteo Mantoani, Rachik Soualah, Amelia Jean Brennan, Ulrich Parzefall, M. Ziolkowski, Scott Snyder, Michael Homann, Carlos Lacasta, Masaya Ishino, Ewelina Lobodzinska, Shaun Roe, Matthew Beckingham, X. Y. Zhang, Z. Hajduk, Olga Rezanova, EB Noccioli, Samuel Calvet, Simonetta Gentile, DS Saadi, Igor Aleksandrov, J. B. Liu, Richard Peschke, Monica Dunford, Andreas Salzburger, J. Maneira, Lorenzo Rinaldi, Elin Bergeaas Kuutmann, Khy Wong, H. De la Torre, Philip Patrick Allport, Christoph Rembser, Agnieszka Leyko, H. von der Schmitt, Gorm Aske Gram Krohn Galster, Diego Casadei, Doris Chromek-Burckhart, Karola Dette, Maria Rescigno, Michal Svatos, Michael Davies, C. Schmitt, Erez Etzion, M. Werner, Francois Corriveau, Elias Coniavitis, Remie Hanna, Flavia De Almeida Dias, David Robinson, Max Baak, Claudio Gatti, Stefan Kluth, P. C. Van Der Deijl, Josephine Wittkowski, Shlomit Tarem, Jia Jian Teoh, Tiesheng Dai, Christian Luedtke, Barbara Alvarez Gonzalez, Scharf, Martin Nagel, A. Canepa, I. van Vulpen, Giulio Aielli, W. S. Lockman, D. Liu, Avishek Chatterjee, Nooshin Dehghanian, Duong Nguyen, Gagik Vardanyan, Alexey Maslennikov, F. Anulli, Serkant Ali Cetin, Gerhard Ferdinand Rzehorz, Kuhan Wang, Jane Cummings, R. P. Middleton, Leonardo Paolo Rossi, Graham Cree, James Dassoulas, Phs De Bruin, Holger Schulz, Jose F Benitez, Jianming Qian, Scarlet Norberg, E. V. Bouhova-Thacker, Laurie Iain McClymont, Shi Che, Frank Paige, Else Lytken, Manuel Schreyer, Andrea Ventura, Amanda R. Vest, Speranza Falciano, S. B. King, Jing Guo, Laurent Schoeffel, Thomas Balestri, Mikhail Mineev, Lotte Ansgaard Thomsen, Richard Polifka, Stefan Simion, Tobias Bisanz, Philip Phillips, Samuel Silverstein, and Radescu
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Physics ,Particle physics ,Large Hadron Collider ,Luminosity (scattering theory) ,Meson ,010308 nuclear & particles physics ,High Energy Physics::Phenomenology ,Electroweak interaction ,General Physics and Astronomy ,Phi meson ,01 natural sciences ,Nuclear physics ,medicine.anatomical_structure ,Atlas (anatomy) ,0103 physical sciences ,medicine ,Higgs boson ,High Energy Physics::Experiment ,010306 general physics ,Boson - Abstract
A search for the decays of the Higgs and Z bosons to a ϕ meson and a photon is performed with a pp collision data sample corresponding to an integrated luminosity of 2.7 fb^{-1} collected at sqrt[s]=13 TeV with the ATLAS detector at the LHC. No significant excess of events is observed above the background, and 95% confidence level upper limits on the branching fractions of the Higgs and Z boson decays to ϕγ of 1.4×10^{-3} and 8.3×10^{-6}, respectively, are obtained.
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- 2016
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5. SEARCH FOR NEW SEQUENTIAL LEPTONS IN E+E- ANNIHILATION AT PETRA ENERGIES
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John Freeman, M. Ogg, Walter Dr. Hillen, D. M. Binnie, G. Peise, H. Hartmann, F. J. Kirschfink, W. Wallraff, H. M. Fischer, W. Koch, J. Proudfoot, H. Hultschig, B. H. Wiik, T. Barklow, S. Yarker, P. J. Dornan, G. Poelz, G. Rudolph, D. G. Cassel, E. Hilger, E.E. Ronat, R. Rüsch, Rj Cashmore, J. Pyrlik, H. Boerner, G. Knop, D. Heyland, R. A. Stern, Ehud Duchovni, D. H. Saxon, P. Joos, R.C.E. Devenish, R. Brandelik, E. Wicklund, M. A. Downie, D.W. Schmitz, J. C. Hart, P. Mättig, John Illingworth, R. Wedemeyer, AS von Dratzig, P. L. Woodworth, O. Römer, Gl Salmon, T. Meyer, Kadansky, J. Rimkus, H. Kowalski, R. Riethmüller, D. Trines, A. Ladage, Stephen Lloyd, H. G. Sander, K. Lübelsmeyer, P. Söding, Gy. Wolf, P. Koehler, R. Fohrmann, L. Koepke, Hermann Kolanoski, U. Karshon, Y. Eisenberg, P. Grossmann, U. Kötz, H. Burkhardt, D. Notz, S Lan Wu, I. C. Brock, G Zobernig, C. Youngman, A. Shapira, D. A. Garbutt, W. G. Jones, Kw Bell, P. Schmüser, M. Holder, K. Gather, I. Al-Agil, D. Revel, P. Leu, D. Lüke, G. Mikenberg, W. Braunschweig, P. Lecomte, B. Foster, J. Sedgbeer, H. L. Lynch, T. R. Wyatt, D. Pandoulas, Hu Martyn, Quarrie, M. Wollstadt, and N Wermes
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Nuclear physics ,Physics ,Nuclear and High Energy Physics ,Particle physics ,Annihilation ,Lepton - Published
- 2016
6. Evaluation of the local hadronic calibration with combined beam-test data for the endcap and forward calorimeters of ATLAS in the pseudorapidity region
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J. P. Archambault, A. Savin, Mohsen Khakzad, P. Delsart, V. Drobin, Sylvain Tisserant, Pavol Strizenec, R. Othegraven, R. Langstaff, Namig Javadov, R. K. Keeler, C. Zeitnitz, M. Schram, A. B. Lazarev, J. Rani, Yu. A. Tikhonov, Michel Raymond, Andrey Kiryunin, C. Benchouk, John Rutherfoord, Michael Shupe, Ph. Schwemling, Andrei Akimov, H. M. Braun, Andrei Snesarev, T. Schliephake, M. Qi, W. Shaw, R. S. Orr, Georges Azuelos, Martin Nagel, C. D. Cojocaru, Claude Leroy, Vladimir Datskov, J. Soukup, M. Blagov, L. Petrova, Vladimir Sulin, Jozsef Toth, L. L. Ma, Alexey Maslennikov, Fares Djama, A.M. Moiseev, F. Labarga, D. Stoyanova, A. Fedorov, Rachid Mazini, M.L. Levitsky, N. S. Knecht, D. Schouten, L. Kurchaninov, J. Del Peso, Yu. A. Usov, Jialun Ping, G. Y. Mitrofanov, Alexey Talyshev, H. Secker, Sven Menke, E. Nebot, Denis Salihagic, M. Wielers, S. Rodier, Johannes Erdmann, G. E. Pospelov, Michel Vetterli, L. Zakamsky, P. A. Gorbounov, Horst Oberlack, Jibu P. Thomas, Fernando Barreiro, Gerald Oakham, V. N. Evdokimov, A. Shalyugin, C. J. Oram, A. A. Minaenko, Pavel Shatalov, Peter Loch, M. Pecsy, M. Bieri, Margret Fincke-Keeler, A. Pleskatch, P. Cavalleri, V. Epshtein, C. Galt, M. Heldmann, V. Khovansky, Peter Krieger, Emmanuel Monnier, N. Kanaya, Cedric Serfon, V. A. Kalinnikov, Manuella Vincter, P. Stavina, A. B. Neganov, Andrey Soukharev, M. Yakimenko, S. Golubykh, I.L. Pisarev, S. P. Denisov, M. Y. Kazarinov, E. Serochkin, D. Sauvage, Teresa Barillari, Victor Kukhtin, R. Mehdiyev, Sergey Chekulaev, Aston Komar, L. Shaver, N. Rousakovitch, B. Resende, S. N. Shilov, V. Niess, Peter Schacht, Michel Lefebvre, Evgueni Ladygin, M. Speransky, D. Schroff, J. Thadome, T. Chen, James Pinfold, S. Kakurin, Pascal Pralavorio, C. Oliver, Fabrice Hubaut, T. Hughes, Carolina Gabaldon, M. J. Losty, Robert McPherson, A. Belkin, and L. Koepke
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Physics ,Nuclear and High Energy Physics ,Particle physics ,Physics::Instrumentation and Detectors ,ATLAS experiment ,Calorimeter ,Nuclear physics ,medicine.anatomical_structure ,Atlas (anatomy) ,Pseudorapidity ,medicine ,Calibration ,Measuring instrument ,High Energy Physics::Experiment ,Rapidity ,Instrumentation ,Test data - Abstract
The local hadronic calibration scheme developed for the reconstruction and calibration of jets and missing transverse energy in ATLAS has been evaluated using data obtained during combined beam tests of modules of the ATLAS liquid argon endcap and forward calorimeters. These tests covered the pseudorapidity range of 2.5 | η | 4.0 . The analysis has been performed using special sets of calibration weights and corrections obtained with the G eant 4 simulation of a detailed beam-test setup. The evaluation itself has been performed through the careful study of specific calorimeter performance parameters such as e.g. energy response and resolution, shower shapes, as well as different physics lists of the G eant 4 simulation.
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- 2012
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7. An absence of neutrinos associated with cosmic-ray acceleration in gamma-ray bursts
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C. Walck, Todor Stanev, Dawn Williams, S. Hussain, J. W. Nam, F. Descamps, M. W. E. Smith, D. J. Koskinen, P. Berghaus, S. Boeser, S. Japaridze, S. Odrowski, Timo Karg, H. Landsman, R. Franke, S. Euler, S. Flis, H. A. B. Johansson, Christian Bohm, Aongus O'Murchadha, Jon Dumm, T. Waldenmaier, S. Westerhoff, Thomas K. Gaisser, G. B. Yodh, J. J. Beatty, S. Seunarine, M. Kowalski, A. Gross, Damian Pieloth, A. M. Brown, P. B. Price, K. Hoshina, H. S. Matis, L. Koepke, M. Danninger, D. Heereman, M. V. D'Agostino, G. C. Hill, J. Posselt, M. Stamatikos, D. Z. Besson, T. O. B. Schmidt, Glenn Spiczak, Larissa Paul, L. Schulte, Chris Wendt, T. Kowarik, D. Rutledge, M. Labare, Albrecht Karle, M. Schunck, Michael J. Baker, Klas Hultqvist, A. Marotta, D. Altmann, U. Naumann, K. Meagher, T. R. Wood, J. Kiryluk, Thomas Meures, N. van Eijndhoven, L. Gladstone, M. Richman, Francis Halzen, Reina H. Maruyama, K. H. Becker, Dirk Heinen, D. Seckel, S. Miarecki, P. Zarzhitsky, A. Piegsa, Kurt Woschnagg, Paul Evenson, Xinhua Bai, A. Goldschmidt, F. Rothmaier, Segev BenZvi, Carsten Rott, Dave Nygren, J. Miller, Spencer Klein, R. J. Lauer, O. Fadiran, M. Bissok, Markus Ahlers, A. R. Fazely, Tyce DeYoung, C. DeClercq, P. A. Toale, Hermann Kolanoski, J. A. Goodman, A. Silvestri, K. Mase, M. Merck, Xianwu Xu, G. Kroll, T. Degner, K. Rawlins, R. Hellauer, J. P. Huelss, M. L. Benabderrahmane, Darren Grant, Dmitry Chirkin, Jay Gallagher, R. Nahnhauer, Karen S. Caballero-Mora, Kara Hoffman, Y. Sestayo, Karen Andeen, S. Grullon, M. J. Carson, A. H. Cruz Silva, N. Milke, Jenni Adams, S. Schoeneberg, Sarah Nowicki, Alexander Kappes, C. Pérez de los Heros, Samvel Ter-Antonyan, James Madsen, A. Olivas, M. J. Larson, A. Homeier, S. Panknin, R. Stroem, Fabian Kislat, A. Stoessl, Markus Ackermann, J. Dreyer, S. Tilav, A. Schultes, O. Engdegård, J. C. Díaz-Vélez, Juanan Aguilar, Wolfgang Rhode, T. Gluesenkamp, Takao Kuwabara, Simona Toscano, R. Wasserman, Y. Abdou, Christopher Wiebusch, Nathan Whitehorn, S. Hickford, A. Schoenwald, A. Van Overloop, Kael Hanson, W. Huelsnitz, J. Daughhetee, Christian Spiering, T. Griesel, B. Christy, Seth M. Cohen, R. W. Ellsworth, Donglian Xu, K. Wiebe, A. Franckowiak, R. G. Stokstad, R. Wischnewski, Matt Dunkman, Steven W. Barwick, Teresa Montaruli, K. Helbing, T. Abu-Zayyad, T. Fischer-Wasels, Elisa Resconi, S. Bechet, B. Hoffmann, Dariusz Gora, Anatoli Fedynitch, A. Schukraft, K. Laihem, J. L. Bazo Alba, J. Berdermann, D. Bose, E. Jacobi, J. Luenemann, H. Taavola, J. Feintzeig, Dirk Ryckbosch, Subir Sarkar, P. Redl, M. Olivo, Paolo Desiati, T. Feusels, D. Berley, E. A. Strahler, Ignacio Taboada, E. Blaufuss, J. C. Davis, K. Beattie, O. Schulz, E. Middell, Elisa Bernardini, D. J. Boersma, M. Krasberg, J. E. Jacobsen, Marcos Santander, M. Ribordy, L. Gerhardt, J. P. Rodrigues, Matthias Wolf, T. Stezelberger, K. Han, Michael S. Bell, Kirill Filimonov, M. Vehring, D. F. Cowen, R. C. Bay, B. Ruzybayev, C. Ha, S. Yoshida, M. Casier, G. W. Sullivan, P. Meszaros, J. K. Becker, Allan Hallgren, Sandro Kopper, S. M. Movit, H. G. Sander, C. Colnard, Aya Ishihara, Rasha Abbasi, Chun Xu, Ch. Weaver, Chad Finley, M. Stueer, K. Schatto, G. Kohnen, J. Blumenthal, P. O. Hulth, J. Eisch, G. de Vries-Uiterweerd, Olga Botner, D. Tosi, B. Semburg, H. Wissing, Stijn Buitink, J. Auffenberg, Daniel Bindig, Gerald Przybylski, R. Morse, M. Zoll, Benedikt Riedel, Tim Ruhe, M. Walter, A. Rizzo, S. H. Seo, J. H. Koehne, F. Clevermann, J. P. Yanez, A. Haj Ismail, A. Tamburro, L. Brayeur, J. van Santen, J. Kunnen, Naoko Kurahashi, D. Bertrand, M. Wallraff, M. Voge, M. Gurtner, M. Dierckxsens, Physics, Elementary Particle Physics, Aguilar Sanchez, Juan, and Montaruli, Teresa
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Physics::Instrumentation and Detectors ,Astronomy ,Astrophysics::High Energy Astrophysical Phenomena ,Electronvolt ,FOS: Physical sciences ,Flux ,high-energy neutrinos ,Cosmic ray ,ddc:500.2 ,Astrophysics ,Astrophysics::Cosmology and Extragalactic Astrophysics ,7. Clean energy ,01 natural sciences ,ddc:070 ,Icecube ,Acceleration ,Pion ,cosmic rays ,0103 physical sciences ,Telescope ,010303 astronomy & astrophysics ,Very Energetic ,High Energy Astrophysical Phenomena (astro-ph.HE) ,Physics ,Multidisciplinary ,010308 nuclear & particles physics ,High Energy Physics::Phenomenology ,Search ,Astrophysics::Instrumentation and Methods for Astrophysics ,13. Climate action ,Gamma Ray Bursts ,High Energy Physics::Experiment ,Neutrino ,Gamma-ray burst ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
Gamma-Ray Bursts (GRBs) have been proposed as a leading candidate for acceleration of ultra high-energy cosmic rays, which would be accompanied by emission of TeV neutrinos produced in proton-photon interactions during acceleration in the GRB fireball. Two analyses using data from two years of the IceCube detector produced no evidence for this neutrino emission, placing strong constraints on models of neutrino and cosmic-ray production in these sources., 6 pages, 4 figures. Additional supplementary information (effective areas) is freely available with the published version. Version 2 supersedes the published version and fixes a small overestimation of the event rate from the Guetta et al. model in the 2010-2011 part of the model-dependent analysis, resulting in a new Fig. 1. Conclusions and all final results are unchanged.
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- 2012
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8. Performance of the ATLAS liquid argon endcap calorimeter in the pseudorapidity region in beam tests
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Evgueni Ladygin, M. Speransky, D. Schroff, Robert McPherson, Margret Fincke-Keeler, A. Belkin, Michel Raymond, Andrey Kiryunin, Cedric Serfon, G. E. Pospelov, A. B. Lazarev, M. Yakimenko, A. Savin, Rachid Mazini, Alexey Maslennikov, F. Labarga, Richard Keeler, W. Shaw, M. Bieri, J. P. Archambault, Peter Schacht, Claude Leroy, Mohsen Khakzad, Dugan O'Neil, Jozsef Toth, Dusan Bruncko, L. Zakamsky, L. L. Ma, M. Schram, T. Ince, N. Kanaya, Alexey Talyshev, A. Karev, M. Qi, Carolina Gabaldon, T. Chen, James Pinfold, A. Neganov, J. Soukup, R. Langstaff, R. Othegraven, Michel Vetterli, S. Kakurin, Gerald Oakham, Christian Zeitnitz, Yu. A. Usov, P. Cavalleri, S. Golubykh, I.L. Pisarev, M. J. Losty, Fernando Barreiro, Horst Oberlack, M. Lefebvre, Georges Azuelos, A. Shalyugin, Pavol Strizenec, John Rutherfoord, P. Mooshofer, Vladimir Datskov, J. Huber, R. Mehdiyev, A. Pleskatch, M.L. Levitsky, V. Khovansky, T. Schliephake, Andrey Soukharev, J. Rani, Jibu P. Thomas, C. J. Oram, Aston Komar, L. Shaver, L. Kurchaninov, Sven Menke, Jialun Ping, V. Epshtein, M. Lenckowski, H. M. Braun, N. S. Knecht, D. Schouten, M. Aderholz, P. Stavina, Teresa Barillari, A. Fischer, P. Birney, C. Galt, Vassili Kazanin, W D Cwienk, Peter Krieger, Vladimir Sulin, C. Benchouk, Victor Kukhtin, C. D. Cojocaru, M. Heldmann, N. Rousakovitch, B. Resende, T. Hughes, L. Petrova, V. M. Malyshev, I. Gable, Emmanuel Monnier, V. A. Kalinnikov, Manuella Vincter, S. N. Shilov, Pascal Pralavorio, T. A. Hodges, A. A. Minaenko, A. Fedorov, Denis Salihagic, C. Oliver, Eduard Kladiva, J. Thadome, P. A. Gorbounov, Namig Javadov, Fabrice Hubaut, Ph. Schwemling, Andrei Akimov, P. Delsart, V. Drobin, Sylvain Tisserant, R. Snopkov, Andrei Snesarev, L. Koepke, V. Niess, M. Blagov, Robert Orr, J. Del Peso, Fares Djama, S. P. Denisov, M. Y. Kazarinov, E. Serochkin, D. Sauvage, M. Wielers, A.M. Moiseev, J Habring, Sergey Chekulaev, H. Secker, E. Nebot, Peter Loch, Michael Shupe, V.N. Evdokimov, G. Y. Mitrofanov, S. Rodier, Y. A. Tikhonov, Pavel Shatalov, and D. Stoyanova
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Physics ,Nuclear and High Energy Physics ,Particle physics ,Muon ,Large Hadron Collider ,Physics::Instrumentation and Detectors ,010308 nuclear & particles physics ,01 natural sciences ,Calorimeter ,Nuclear physics ,medicine.anatomical_structure ,Pion ,Atlas (anatomy) ,Pseudorapidity ,0103 physical sciences ,medicine ,Cathode ray ,High Energy Physics::Experiment ,Nuclear Experiment ,010306 general physics ,Instrumentation ,Beam (structure) - Abstract
The pseudorapidity region 2.5 | η | 4.0 in ATLAS is a particularly complex transition zone between the endcap and forward calorimeters. A set-up consisting of 1 4 resp. 1 8 of the full azimuthal acceptance of the ATLAS liquid argon endcap and forward calorimeters has been exposed to beams of electrons, pions and muons in the energy range E ⩽ 200 GeV at the CERN SPS. Data have been taken in the endcap and forward calorimeter regions as well as in the transition region. This beam test set-up corresponds very closely to the geometry and support structures in ATLAS. A detailed study of the performance in the endcap and forward calorimeter regions is described. The data are compared with MC simulations based on GEANT 4 models.
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- 2008
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9. Determining neutrino oscillation parameters from atmospheric muon neutrino disappearance with three years of IceCube DeepCore data
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K. Hoshina, L. Koepke, Glenn Spiczak, A. Koob, Timo Karg, J. Luenemann, U. Naumann, Mohamed Rameez, E. Unger, T. Feusels, P. B. Price, Christian Spiering, J. E. Jacobsen, Marcos Santander, T. O. B. Schmidt, Justin Vandenbroucke, T. R. Wood, L. Gerhardt, D. Hellwig, A. O'Murchadha, Kurt Woschnagg, K. Frantzen, K. Rawlins, Paul Evenson, S. Hussain, D. J. Koskinen, Mike Richman, T. De Young, J. H. Koehne, Joakim Sandroos, Azadeh Keivani, F. Clevermann, Y. Sestayo, J. Feintzeig, Dmitry Chirkin, S. Zierke, I. Rees, Maria Tselengidou, A. Omairat, Alexander Kappes, P. Hallen, James Madsen, Klas Hultqvist, J. Kiryluk, Darren Grant, J. Casey, A. Kriesten, Carsten Rott, Sarah Nowicki, J. A. Goodman, D. R. Nygren, J. P. A. M. de André, M. Stamatikos, Dennis Soldin, K. Schatto, G. Kohnen, J. P. Yanez, G. W. Sullivan, Kurt Becker, M. N. Tobin, S. Schoenen, N. A. Stanisha, B. J. Whelan, O. Schulz, M. Bissok, M. J. Larson, T. Anderson, M. Relich, H. Taavola, Jürgen Brunner, E. Blaufuss, D. J. Boersma, J. C. Davis, L. Raedel, Takao Kuwabara, S. Yoshida, Teresa Montaruli, K. Jagielski, D. Z. Besson, Anatoli Fedynitch, J. Auffenberg, Jenni Adams, K. Clark, K. Krings, A. Obertacke, C. Walck, Benedikt Riedel, A. Goldschmidt, M. Kowalski, Thomas Meures, K. D. de Vries, Jean Gallagher, Xianwu Xu, M. Leuermann, A. Tamburro, M. Lesiak-Bzdak, P. Redl, G. Tešić, W. Huelsnitz, M. Vehring, D. F. Cowen, A. Stasik, N. van Eijndhoven, K. Mase, H. S. Matis, P. Gretskov, A. Franckowiak, C. Ha, F. Bos, Nathan Whitehorn, Allan Hallgren, E. A. Strahler, Gerald Przybylski, Oe. Penek, Javier Gonzalez, Matt Dunkman, A. Haj Ismail, Giorgio Maggi, E. Middlemas, G. Kroll, K. Helbing, S. Hickford, A. Schoenwald, N. Buzinsky, T. Fischer-Wasels, J. Felde, C. Haack, J. Ziemann, M. Quinnan, C. Pérez de los Heros, Hermann Kolanoski, D. T. Larsen, R. G. Stokstad, C. De Clercq, S. Euler, C. Pfendner, Tim Ruhe, René Reimann, Sandro Kopper, C. Kopper, G. Golup, A. Schukraft, Matthias Vraeghe, P. O. Hulth, J. Eisch, M. Day, J. L. Kelley, J. Blumenthal, M. Wellons, Markus Ahlers, A. Stoessl, Kirill Filimonov, Dariusz Gora, M. Usner, E. Cheung, Carlos Arguelles, Francis Halzen, P. Zarzhitsky, S. De Ridder, M. Schmitz, K. Jero, M. Labare, P. Berghaus, Kael Hanson, H. Wissing, B. Eichmann, J. Klaes, Markus Ackermann, S. W. Barwick, R. Ström, O. Fadiran, Dirk Ryckbosch, Martin Rongen, Olga Botner, J. Kunnen, V. Baum, J. J. Beatty, Maryon Ahrens, Daniel Bindig, M. Medici, B. Ruzybayev, Samvel Ter-Antonyan, Paolo Desiati, X. Bai, S. Coenders, Damian Pieloth, M. Kauer, J. Becker Tjus, Surujhdeo Seunarine, J. Miller, Martin Wolf, Ali Kheirandish, A. M. Brown, J. Posselt, K. Wiebe, Joshua Pepper, D. Gier, L. Classen, Hans Niederhausen, Juanan Aguilar, T. Fuchs, B. Kaminsky, D. Bose, B. Christy, A. Ishihara, M. W. E. Smith, E. Middell, Elisa Bernardini, S. Odrowski, Ch. Weaver, R. Gaior, L. Brayeur, T. Palczewski, N. Kurahashi, N. Milke, George Japaridze, Marcel Zoll, Segev BenZvi, Reina H. Maruyama, Todor Stanev, Dawn Williams, C. Wendt, S. Boeser, O. Jlelati, I. Taboada, Dustin Hebecker, Spencer Klein, J. Puetz, C. Wichary, A. Olivas, S. Flis, S. Tilav, R. Hoffmann, M. Wallraff, J. van Santen, E. Jacobi, Elisa Resconi, M. Voge, A. Bernhard, B. Eberhardt, R. Eagan, Thomas K. Gaisser, G. B. Yodh, Chad Finley, A. Homeier, F. Huang, Christopher Wiebusch, E. Pinat, T. Gluesenkamp, Kara Hoffman, Gary Binder, M. Casier, A. H. Cruz Silva, A. Tepe, Sofia Vallecorsa, N. L. Strotjohann, J. Daughhetee, Donglian Xu, M. Jurkovic, Wolfgang Rhode, A. Meli, Christian Bohm, R. C. Bay, H. G. Sander, D. Berley, G. C. Hill, Rezo Shanidze, Juan Carlos Diaz-Velez, L. Gladstone, Dirk Heinen, A. Gross, D. Seckel, S. Miarecki, M. Kroll, Subir Sarkar, A. R. Fazely, P. A. Toale, J. C. Groh, R. Maunu, A. Terliuk, S. Westerhoff, Justin Lanfranchi, R. Morse, D. Heereman, R. Hellauer, S. Schoeneberg, Sally Robertson, A. Christov, Larissa Paul, J. P. Rodrigues, T. C. Arlen, T. Stezelberger, S. M. Saba, F. Scheriau, Albrecht Karle, D. Altmann, K. Meagher, Delia Tosi, M. G. Aartsen, H.-P. Bretz, Frank McNally, L. Schulte, R. Nahnhauer, and L. Mohrmann
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Nuclear and High Energy Physics ,Particle physics ,Physics - Instrumentation and Detectors ,TELESCOPE ,Physics::Instrumentation and Detectors ,Solar neutrino ,Astrophysics::High Energy Astrophysical Phenomena ,FOS: Physical sciences ,High Energy Physics - Experiment ,High Energy Physics - Experiment (hep-ex) ,TRACK RECONSTRUCTION ,Muon neutrino ,ddc:530 ,Neutrino oscillation ,Physics ,High Energy Physics::Phenomenology ,Instrumentation and Detectors (physics.ins-det) ,Solar neutrino problem ,PERFORMANCE ,Neutrino detector ,Physics and Astronomy ,Measurements of neutrino speed ,High Energy Physics::Experiment ,Astrophysics::Earth and Planetary Astrophysics ,Neutrino ,Neutrino astronomy ,SYSTEM - Abstract
We present a measurement of neutrino oscillations via atmospheric muon neutrino disappearance with three years of data of the completed IceCube neutrino detector. DeepCore, a region of denser instrumentation, enables the detection and reconstruction of atmospheric muon neutrinos between 10 GeV and 100 GeV, where a strong disappearance signal is expected. The detector volume surrounding DeepCore is used as a veto region to suppress the atmospheric muon background. Neutrino events are selected where the detected Cherenkov photons of the secondary particles minimally scatter, and the neutrino energy and arrival direction are reconstructed. Both variables are used to obtain the neutrino oscillation parameters from the data, with the best fit given by $\Delta m^2_{32}=2.72^{+0.19}_{-0.20}\times 10^{-3}\,\mathrm{eV}^2$ and $\sin^2\theta_{23} = 0.53^{+0.09}_{-0.12}$ (normal mass hierarchy assumed). The results are compatible and comparable in precision to those of dedicated oscillation experiments., Comment: 10 pages, 7 figures
- Published
- 2015
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10. Hadronic calibration of the ATLAS liquid argon end-cap calorimeter in the pseudorapidity region in beam tests
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A. Pleskatch, A.M. Moiseev, Vladimir Sulin, J Habring, R. Langstaff, M. Yakimenko, Victor Kukhtin, Fernando Barreiro, Jibu P. Thomas, T. A. Hodges, V. A. Kalinnikov, Christian Zeitnitz, Manuella Vincter, Vladimir Datskov, P. Barrillon, L. Koepke, Margret Fincke-Keeler, Karl Jakobs, Andrei Akimov, M.L. Levitsky, Emmanuel Monnier, Pascal Pralavorio, G. Garcia, R. Snopkov, V.V. Sytnik, J. Del Peso, Fares Djama, N. Rousakovitch, Jialun Ping, S. N. Shilov, Cedric Serfon, G. E. Pospelov, P. Mooshofer, I. Gable, P. Birney, Georges Azuelos, G. Kolatchev, M. Aderholz, Eduard Kladiva, Horst Oberlack, Sylvain Tisserant, A. Karev, Andrey Soukharev, N. Kanaya, Yu. A. Usov, Fabrice Hubaut, A. Fischer, Jozsef Toth, W D Cwienk, Vassili Kazanin, Michel Raymond, A. A. Minaenko, R. Chytracek, G. Y. Mitrofanov, T. Ince, R. Othegraven, S. Golubykh, I.L. Pisarev, C.D. Cojocaru, L. Zakamsky, R. Mehdiyev, S. Rodier, Pavol Strizenec, Sven Menke, A. B. Lazarev, T. Barillari, A. Shousharo, Aston Komar, Richard Keeler, W. Aoulthenko, Claude Leroy, T. Hughes, Andrey Kiryunin, F. Henry-Couannier, M. Qi, Y. A. Tikhonov, C. Benchouk, M. J. Losty, J. Soukup, J. Huber, L. Kurchaninov, C. J. Oram, M. Heldmann, A. Shalyugin, Alexey Maslennikov, F. Labarga, Denis Salihagic, C. Olivier, Namig Javadov, J. Thadome, Andrei Snesarev, M. Blagov, T. Chen, L. Hinz, James Pinfold, A. Neganov, S. Kakurin, H. Bartko, A. Talychev, Michel Lefebvre, M. Lenckowski, Evgueni Ladygin, M. Speransky, D. Schroff, Peter Schacht, H. M. Braun, Robert McPherson, A. Fedorov, S. P. Denisov, M. Y. Kazarinov, E. Serochkin, D. Sauvage, M. Wielers, Sergey Chekulaev, Dusan Bruncko, and W. Malychev
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GEANT-3 ,Physics ,Nuclear and High Energy Physics ,Particle physics ,Large Hadron Collider ,Physics::Instrumentation and Detectors ,010308 nuclear & particles physics ,Monte Carlo method ,Hadron ,01 natural sciences ,7. Clean energy ,Calorimeter ,Nuclear physics ,medicine.anatomical_structure ,Atlas (anatomy) ,Pseudorapidity ,0103 physical sciences ,medicine ,High Energy Physics::Experiment ,Nuclear Experiment ,010306 general physics ,Instrumentation ,Beam (structure) - Abstract
A full azimuthal φ -wedge of the ATLAS liquid argon end-cap calorimeter has been exposed to beams of electrons, muons and pions in the energy range 6 GeV ⩽ E ⩽ 200 GeV at the CERN SPS. The angular region studied corresponds to the ATLAS impact position around the pseudorapidity interval 1.6 | η | 1.8 . The beam test setup is described. A detailed study of the performance is given as well as the related intercalibration constants obtained. Following the ATLAS hadronic calibration proposal, a first study of the hadron calibration using a weighting ansatz is presented. The results are compared to predictions from Monte Carlo simulations, based on GEANT 3 and GEANT 4 models.
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- 2004
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11. Alport-Syndrom und familiäre benigne Hämaturie Eine Übersicht über hereditäre Erkrankungen des Typ-IV-Kollagens der Gefäßbasalmembranen
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O. Gross, M.-L. Koepke, and M. Weber
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Nephrology ,business.industry ,Internal Medicine ,Medicine ,business - Published
- 2004
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12. The tagging detector of the CP-violation experiment NA48 at CERN
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A. Winhart, M. Markytan, H. Blümer, G. Fischer, K.H. Geib, Anton Taurok, P. Cenci, Manfred Jeitler, M. Pernicka, H. Dibon, P. Lubrano, C. Ebersberger, Z. Kulka, Ivan Mikulec, Konrad Kleinknecht, H. Bergauer, M. Calvetti, V. Schönharting, L. Koepke, G. Neuhofer, and A. Papi
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Nuclear physics ,Physics ,Nuclear and High Energy Physics ,Pion ,Large Hadron Collider ,Meson ,Detector ,Measuring instrument ,CP violation ,Instrumentation ,Particle detector ,Beam (structure) - Abstract
The CP-violation experiment NA48 at CERN aims at measuring direct CP-violation in the decays of neutral kaons into π + π − and π 0 π 0 . The experiment uses simultaneous, almost collinear beams of neutral K L 0 and K S 0 mesons, which are produced on two different targets. K S 0 events are “tagged” by measuring the times of the protons that fly towards the K S 0 production target. In order to sustain the high rate of 10 7 protons/s in this beam without suffering from too many pile-up events, the detector consists of 24 separate scintillators (12 horizontal and 12 vertical), each of which sees only a small fraction of the beam. Their signals are digitized by specially developed 1 GHz FADCs. The exact time of a pulse is established offline by a fit procedure. The detector and its electronics have been successfully used during test beams in 1994–1996 and during the first physics run of NA48 in 1997. The inefficiency of the detector has been measured to 2×10 −4 . Sources of background have been identified to allow for off-line correction. The mechanical setup of the detector, the 1 GHz FADC and results from the test and data runs are presented.
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- 1998
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13. Cooperation, Not Conflict: Curés and Primary School Inspectors in July Monarchy France, 1833–1848
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Robert L. Koepke
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Cultural Studies ,History ,Monarchy ,Political science ,Religious studies ,Ethnology - Abstract
Les inspecteurs de l'ecole primaire francaise sous la Monarchie de Juillet affirment que les cures francais ne sont pas des opposants obscurantistes, mais des leaders enthousiastes a l'egard du mouvement de scolarisation en France. Les inspecteurs rapportent rarement des conflits entre cures et maitres d'ecole. Si conflit il y avait, ceux-ci etaient plutot dus a des problemes personnels qu'a des oppositions de principe, de politique ou de foi. Avant le Revolution de 1848, le clerge est largement partisan de la politique scolaire de l'Etat. Il semble que cette cooperation ait ete stoppee avec la revolution
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- 1995
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14. The design and performance of IceCube DeepCore
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T. Griesel, K. Wiebe, Carsten Rott, Dave Nygren, J. Miller, M. Bissok, Xianwu Xu, S. Boeser, C. Ha, K. Rawlins, P. Berghaus, M. L. Benabderrahmane, Jay Gallagher, J. K. Becker, R. Nahnhauer, Q. Swillens, Christian Bohm, Aongus O'Murchadha, James Madsen, Jon Dumm, S. Euler, T. Waldenmaier, Thomas Meures, Joanna Kiryluk, A. Stoessl, M. Kowalski, M. Danninger, T. Kowarik, C. Walck, R. Ström, J. Petrovic, A. Olivas, A. Gross, Ignacio Taboada, Teresa Montaruli, S. Grullon, M. J. Carson, K. Andeen, M. V. D'Agostino, Timo Karg, Chris Wendt, M. Stamatikos, Damian Pieloth, M. Labare, P. B. Price, Paraic A. Kenny, Juanan Aguilar, M. J. Larson, M. Merck, A. M. Brown, Takao Kuwabara, A. Tamburro, Xinhua Bai, Markus Ahlers, Allan Hallgren, T. O. B. Schmidt, M. Richman, Fabian Kislat, B. Christy, S. Seunarine, R. Porrata, J. C. Díaz-Vélez, P. O. Hulth, J. Eisch, T. R. Wood, Seth M. Cohen, N. Milke, George Japaridze, R. J. Lauer, W. Huesnitz, Nathan Whitehorn, G. de Vries-Uiterweerd, C. De Clercq, T. Degner, Tim Ruhe, D. Rutledge, M. Walter, Peter Mészáros, O. Engdegård, Kurt Woschnagg, Klas Hultqvist, Samvel Ter-Antonyan, J. A. Goodman, D. Z. Besson, R. Wischnewski, B. Semburg, H. G. Sander, K. Helbing, Markus Ackermann, A. Schultes, Segev BenZvi, Paul Evenson, J. Feintzeig, S. Westerhoff, C. Colnard, Spencer Klein, Aya Ishihara, H. Wissing, A. Marotta, Larissa Paul, Chun Xu, J. Auffenberg, Todor Stanev, Dawn Williams, M. Stueer, Daniel Bindig, B. Hoffmann, F. Descamps, Kara Hoffman, Y. Sestayo, Dmitry Chirkin, H. Taavola, K. Beattie, Albrecht Karle, A. Silvestri, Christian Spiering, A. Tepe, A. H. Cruz Silva, Stijn Buitink, A. Piegsa, Ch. Weaver, O. Schulz, E. Blaufuss, J. C. Davis, S. H. Seo, Dariusz Gora, Hermann Kolanoski, R. Franke, K. Han, Elisa Resconi, Alexander Kappes, A. Franckowiak, Matt Dunkman, K. Mase, J. Berdermann, D. Altmann, K. Meagher, Kael Hanson, Thomas K. Gaisser, G. B. Yodh, T. Fischer-Wasels, Justin Vandenbroucke, Chad Finley, R. Morse, G. W. Sullivan, Wolfgang Rhode, M. Schunck, D. Berley, A. Schukraft, K. Laihem, S. M. Movit, R. Hellauer, T. Abu-Zayyad, Rasha Abbasi, H. Landsman, Dirk Ryckbosch, J. P. Huelss, Martin Wolf, S. Bechet, T. Gluesenkamp, L. Demiroers, M. M. Allen, S. Hussain, Simona Toscano, J. H. Koehne, F. Rothmaier, A. Van Overloop, R. W. Ellsworth, Steven W. Barwick, F. Clevermann, P. Redl, D. J. Koskinen, Donglian Xu, Karen S. Caballero-Mora, Darren Grant, M. Olivo, E. Middell, Elisa Bernardini, A. Goldschmidth, M. Ribordy, J. P. Yanez, M. Vehring, D. F. Cowen, F. A. Fedynitch, Jenni Adams, S. Panknin, J. L. Bazo Alba, J. Luenemann, Karl-Heinz Kampert, Kirill Filimonov, J. J. Beatty, S. Tilav, T. Feusels, S. Hickford, A. Schoenwald, J. Dreyer, Subir Sarkar, J. E. Jacobsen, Marcos Santander, R. G. Stokstad, J. Posselt, Y. Abdou, L. Gerhardt, K. Hoshina, L. Koepke, J. W. Nam, Glenn Spiczak, Reina H. Maruyama, D. Bose, E. Jacobi, U. Naumann, Paolo Desiati, K. H. Becker, D. J. Boersma, J. Blumenthal, H. S. Matis, E. A. Strahler, G. C. Hill, Michael J. Baker, L. Gladstone, Dirk Heinen, D. Seckel, S. Miarecki, A. R. Fazely, Tyce DeYoung, P. A. Toale, A. Homeier, Christopher Wiebusch, J. Daughhetee, R. C. Bay, J. van Santen, J. P. Rodrigues, T. Stezelberger, M. Krasberg, Olga Botner, Francis Halzen, P. Zarzhitsky, O. Fadiran, Henrik J. Johansson, S. Yoshida, N. van Eijndhoven, G. Kroll, K. Schatto, G. Kohnen, D. Tosi, Gerald Przybylski, M. Zoll, A. Haj Ismail, B. D. Fox, Naoko Kurahashi, D. Bertrand, M. Wallraff, M. Voge, M. Gurtner, S. Odrowski, M. Dierckxsens, B. Ruzybayev, C. Pérez de los Heros, Physics, and Elementary Particle Physics
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Physics - Instrumentation and Detectors ,Cosmology and Nongalactic Astrophysics (astro-ph.CO) ,Physics::Instrumentation and Detectors ,Astrophysics::High Energy Astrophysical Phenomena ,Dark matter ,FOS: Physical sciences ,Antartica ,Generator ,Astrophysics ,Neutrino telescope ,01 natural sciences ,7. Clean energy ,High Energy Physics - Experiment ,IceCube Neutrino Observatory ,Antarctica ,DeepCore ,Detector ,IceCube ,Neutrino ,High Energy Physics - Experiment (hep-ex) ,WIMP ,0103 physical sciences ,010306 general physics ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,Physics ,Muon ,010308 nuclear & particles physics ,Ice ,ICE ,Astrophysics::Instrumentation and Methods for Astrophysics ,Astronomy ,Astronomy and Astrophysics ,Instrumentation and Detectors (physics.ins-det) ,GENERATOR ,Supernova ,Air shower ,Physics and Astronomy ,Neutrino detector ,13. Climate action ,ddc:540 ,High Energy Physics::Experiment ,Astrophysics - Instrumentation and Methods for Astrophysics ,Astrophysics - Cosmology and Nongalactic Astrophysics - Abstract
The IceCube neutrino observatory in operation at the South Pole, Antarctica, comprises three distinct components: a large buried array for ultrahigh energy neutrino detection, a surface air shower array, and a new buried component called DeepCore. DeepCore was designed to lower the IceCube neutrino energy threshold by over an order of magnitude, to energies as low as about 10 GeV. DeepCore is situated primarily 2100 m below the surface of the icecap at the South Pole, at the bottom center of the existing IceCube array, and began taking physics data in May 2010. Its location takes advantage of the exceptionally clear ice at those depths and allows it to use the surrounding IceCube detector as a highly efficient active veto against the principal background of downward-going muons produced in cosmic-ray air showers. DeepCore has a module density roughly five times higher than that of the standard IceCube array, and uses photomultiplier tubes with a new photocathode featuring a quantum efficiency about 35% higher than standard IceCube PMTs. Taken together, these features of DeepCore will increase IceCube's sensitivity to neutrinos from WIMP dark matter annihilations, atmospheric neutrino oscillations, galactic supernova neutrinos, and point sources of neutrinos in the northern and southern skies. In this paper we describe the design and initial performance of DeepCore., Comment: 22 pages, 13 figures
- Published
- 2012
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15. Background studies for acoustic neutrino detection at the South Pole
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T. Denger, H. Taavola, E. Blaufuss, J. C. Davis, P. O. Hulth, J. Eisch, K. Han, G. de Vries-Uiterweerd, J. J. Beatty, B. Semburg, A. Piegsa, M. Krasberg, C. Pérez de los Heros, H. Wissing, K. Hoshina, L. Koepke, Glenn Spiczak, J. Posselt, Daniel Bindig, S. M. Movit, J. Auffenberg, U. Naumann, S. Yoshida, J. M. Clem, P. Zarzhitsk, A. Van Overloop, Ch. Weaver, Reina H. Maruyama, Jon Dumm, M. Prikockis, T. Waldenmaier, Joanna Kiryluk, K. Beattie, O. Schulz, O. Depaepe, P. B. Price, Chad Finley, T. Griesel, M. Ono, S. Stoyanov, K.-H. Becker, J. L. Bazo Alba, Peter Mészáros, M. Kowalski, J. Luenemann, K. Rawlins, T. Feusels, J. E. Jacobsen, Marcos Santander, L. Gerhardt, Larissa Paul, G. Stephens, S. Westerhoff, D. Bose, T. O. B. Schmidt, M. Danninger, K. Wiebe, T. Fischer-Wasels, James Madsen, A. Schukraft, S. Grullon, M. J. Carson, Segev BenZvi, D. Z. Besson, Spencer Klein, T. Kowarik, A. Marotta, Thomas Meures, E. Middell, Elisa Bernardini, R. C. Bay, J. M. Joseph, M. Ribordy, H. S. Matis, E. A. Strahler, Kurt Woschnagg, N. van Eijndhoven, Dirk Ryckbosch, Juan Carlos Diaz-Velez, Paul Evenson, Teresa Montaruli, P. Roth, Kara Hoffman, Y. Sestayo, M. J. Larson, Albrecht Karle, D. Tosi, J. P. Rodrigues, Anatoli Fedynitch, Stijn Buitink, T. Stezelberger, P. Niessen, A. Tamburro, D. Turcan, M. Dierckxsens, Jenni Adams, Christian Spiering, Nathan Whitehorn, S. Cohen, Fabian Kislat, Xinhua Bai, S. Boeser, Justin Vandenbroucke, I. Taboada, Francis Halzen, C. Ha, Dmitry Chirkin, Alexander Kappes, R. Morse, K. Mase, J. L. Kelley, O. Fadiran, M. Merck, G. Kroll, Markus Ahlers, K. Meagher, B. D. Fox, Wolfgang Rhode, M. L. Benabderrahmane, J. Dreyer, T. Abu-Zayyad, A. Franckowiak, S. Seunarine, Y. Abdou, Carsten Rott, J. Miller, J. P. Huelss, Ph. Herquet, A. Slipak, S. Tilav, A. Stoessl, M. Bissok, S. Hickford, A. Schoenwald, R. G. Stokstad, D. Rutledge, S. Bechet, R. Porrata, Pratik Majumdar, Gerald Przybylski, J. van Santen, R. Wischnewski, P. Redl, D. Heinen, Xianwu Xu, Martin Wolf, C. Colnard, C. Bohm, K. Laihem, M. Stamatikos, M. Olivo, T. Straszheim, Paraic A. Kenny, Juanan Aguilar, D. Bertrand, Samvel Ter-Antonyan, L. Demiroers, J. K. Becker, Takao Kuwabara, Kael Hanson, J. Petrovic, H. G. Sander, B. Christy, S. Hussain, D. J. Koskinen, M. Vehring, D. F. Cowen, Chun Xu, F. Rothmaier, Karl-Heinz Kampert, Kirill Filimonov, A. Ishihara, Matthias Geisler, K. Hultqvist, A. Schultes, P. Berghaus, Timo Karg, B. Ruzybayev, M. M. Foerster, Rasha Abbasi, M. Wallraff, J. Blumenthal, A. Goldschmidt, S. Euler, M. Voge, J. C. Gallagher, M. Gurtner, Darren Grant, S. Panknin, Damian Pieloth, D. Hubert, M. Stüer, A. M. Brown, Paolo Desiati, Allan Hallgren, J. A. Goodman, Sandro Kopper, N. Milke, Olga Botner, George Japaridze, O. Engdegård, Aongus O'Murchadha, Elisa Resconi, J. Berdermann, Henrik J. Johansson, Tim Ruhe, M. Walter, A. Rizzo, T. Gluesenkamp, Simona Toscano, D. Berley, G. C. Hill, R. W. Ellsworth, K. Schatto, G. Kohnen, Michael J. Baker, J. W. Nam, L. Gladstone, D. Seckel, S. H. Seo, Subir Sarkar, D. R. Nygren, A. R. Fazely, Tyce DeYoung, P. A. Toale, S. Odrowski, D. J. Boersma, S.J. Lafebre, A. Homeier, Christopher Wiebusch, J. Daughhetee, J. H. Koehne, F. Clevermann, J. P. Yanez, G. W. Sullivan, James E. Braun, Q. Swillens, R. J. Lauer, C. De Clercq, David A. Williams, S. W. Barwick, Todor Stanev, C. Wendt, F. Descamps, A. Tepe, R. Franke, C. Walck, Thomas K. Gaisser, G. B. Yodh, A. Gross, M. Labare, A. Silvestri, Karen Andeen, R. Nahnhauer, M. Schunck, K. Kuehn, W. Huelsnitz, K. Helbing, R. Ehrlich, A. Olivas, T. Krings, Hermann Kolanoski, H. Landsman, M. V. D'Agostino, and Elementary Particle Physics
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Signals ,TELESCOPE ,Absolute noise level ,Astrophysics::High Energy Astrophysical Phenomena ,Flux ,FOS: Physical sciences ,Astrophysics ,7. Clean energy ,01 natural sciences ,IceCube Neutrino Observatory ,law.invention ,IceCube ,Telescope ,Acoustic neutrino detection ,Neutrino flux limit ,law ,SIGNALS ,0103 physical sciences ,WATER ,Detection theory ,010306 general physics ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,Physics ,Acoustic neutrino detector ,010308 nuclear & particles physics ,Detector ,Astrophysics::Instrumentation and Methods for Astrophysics ,Water ,Astronomy and Astrophysics ,Geodesy ,Noise ,Neutrino detector ,Physics and Astronomy ,13. Climate action ,ddc:540 ,Neutrino ,Astrophysics - Instrumentation and Methods for Astrophysics - Abstract
The detection of acoustic signals from ultra-high energy neutrino interactions is a promising method to measure the tiny flux of cosmogenic neutrinos expected on Earth. The energy threshold for this process depends strongly on the absolute noise level in the target material. The South Pole Acoustic Test Setup (SPATS), deployed in the upper part of four boreholes of the IceCube Neutrino Observatory, has monitored the noise in Antarctic ice at the geographic South Pole for more than two years down to 500 m depth. The noise is very stable and Gaussian distributed. Lacking an in-situ calibration up to now, laboratory measurements have been used to estimate the absolute noise level in the 10 to 50 kHz frequency range to be smaller than 20 mPa. Using a threshold trigger, sensors of the South Pole Acoustic Test Setup registered acoustic pulse-like events in the IceCube detector volume and its vicinity. Acoustic signals from refreezing IceCube holes and from anthropogenic sources have been used to localize acoustic events. Monte Carlo simulations of sound propagating from the established sources to the SPATS sensors have allowed to check corresponding model expectations. An upper limit on the neutrino flux at energies $E_��> 10^{11}$ GeV is derived from acoustic data taken over eight months., 17 pages, 14 figures
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- 2012
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16. Multi-year search for dark matter annihilations in the Sun with the AMANDA-II and IceCube detectors
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A. Piegsa, P. Berghaus, L. Schulte, S. Euler, K.-H. Becker, Donglian Xu, J. Feintzeig, Damian Pieloth, Matt Dunkman, T. Fischer-Wasels, M. Krasberg, A. M. Brown, D. Bose, A. Schukraft, K. Beattie, O. Schulz, K. Laihem, E. A. Strahler, A. Gross, J. P. Rodrigues, T. Stezelberger, Subir Sarkar, Naoko Kurahashi, S. Grullon, M. J. Carson, D. Bertrand, W. Huelsnitz, R. Hellauer, A. Van Overloop, S. Yoshida, M. V. D'Agostino, Dirk Ryckbosch, J. Kiryluk, N. Milke, George Japaridze, K. Rawlins, M. J. Larson, Fabian Kislat, S. Schoeneberg, M. Labare, M. Casier, Peter Mészáros, J. Dreyer, Jon Dumm, O. Engdegård, Y. Abdou, T. Waldenmaier, K. Helbing, J. W. Nam, D. J. Boersma, Anatoli Fedynitch, A. Olivas, A. Stoessl, James Madsen, D. R. Nygren, A. Silvestri, Jenni Adams, M. Stamatikos, M. Kowalski, S. Odrowski, S. Bechet, Carsten Rott, Kael Hanson, A. Franckowiak, M. Danninger, H. S. Matis, J. Miller, M. L. Benabderrahmane, D. Z. Besson, Elisa Resconi, J. Berdermann, P. Redl, F. Rothmaier, M. Wallraff, M. Bissok, M. Olivo, T. Kowarik, M. Voge, J. L. Bazo Alba, R. Wasserman, M. Schunck, K. Mase, M. Gurtner, K. Hultqvist, Darren Grant, Xianwu Xu, J. Luenemann, A. Goldschmidt, Karen Andeen, Thomas Meures, Francis Halzen, K. Hoshina, L. Koepke, Matthias Wolf, S. Hickford, A. Schoenwald, H. Landsman, Glenn Spiczak, C. Bohm, Sarah Nowicki, Juanan Aguilar, P. Zarzhitsky, Takao Kuwabara, T. Feusels, M. Merck, Paolo Desiati, Todor Stanev, O. Fadiran, R. G. Stokstad, C. Wendt, R. Wischnewski, Xinhua Bai, Michael S. Bell, Kirill Filimonov, C. Colnard, N. van Eijndhoven, B. Christy, Seth M. Cohen, J. E. Jacobsen, Marcos Santander, Nathan Whitehorn, S. Panknin, A. Ishihara, C. Pérez de los Heros, U. Naumann, Segev BenZvi, Spencer Klein, Markus Ahlers, L. Gerhardt, Karen S. Caballero-Mora, Dariusz Gora, F. Descamps, T. Gluesenkamp, Simona Toscano, Teresa Montaruli, G. Kroll, R. Nahnhauer, R. W. Ellsworth, D. Heereman, Kara Hoffman, Y. Sestayo, A. H. Cruz Silva, Ch. Weaver, J. K. Becker, S. Tilav, S. Hussain, M. Dierckxsens, R. Franke, S. Westerhoff, Wolfgang Rhode, Samvel Ter-Antonyan, H. G. Sander, D. J. Koskinen, T. Griesel, A. Schultes, J. C. Gallagher, Chad Finley, A. Haj Ismail, E. Middell, Elisa Bernardini, C. Walck, K. Wiebe, M. Ribordy, Christian Spiering, Allan Hallgren, D. Tosi, Sandro Kopper, Chun Xu, Hermann Kolanoski, S. Boeser, Thomas K. Gaisser, G. B. Yodh, I. Taboada, S. Flis, S. Seunarine, D. Rutledge, J. A. Goodman, M. Stueer, A. Marotta, B. Hoffmann, H. Taavola, E. Blaufuss, J. C. Davis, K. Han, L. Brayeur, Stijn Buitink, M. Richman, S. M. Movit, Larissa Paul, R. J. Lauer, C. De Clercq, Gerald Przybylski, M. Zoll, T. Degner, R. Morse, Albrecht Karle, David A. Williams, Markus Ackermann, S. W. Barwick, J. Blumenthal, D. Altmann, K. Meagher, Olga Botner, Henrik J. Johansson, K. Schatto, G. Kohnen, Timo Karg, P. O. Hulth, J. Eisch, G. de Vries-Uiterweerd, B. Semburg, H. Wissing, J. Auffenberg, A. Tamburro, Daniel Bindig, J. van Santen, Rasha Abbasi, J. Kunnen, J. H. Koehne, F. Clevermann, P. B. Price, T. O. B. Schmidt, T. R. Wood, J. P. Yanez, Kurt Woschnagg, Paul Evenson, G. W. Sullivan, Dmitry Chirkin, Alexander Kappes, T. Abu-Zayyad, M. Vehring, D. F. Cowen, C. Ha, Tim Ruhe, M. Walter, A. Rizzo, S. H. Seo, J. P. Huelss, J. J. Beatty, J. Posselt, Reina H. Maruyama, E. Jacobi, R. C. Bay, Juan Carlos Diaz-Velez, A. Homeier, Christopher Wiebusch, J. Daughhetee, B. Ruzybayev, Aongus O'Murchadha, D. Berley, G. C. Hill, Michael J. Baker, L. Gladstone, Dirk Heinen, D. Seckel, S. Miarecki, A. R. Fazely, Tyce DeYoung, P. A. Toale, R. Ström, Aguilar Sanchez, Juan, Montaruli, Teresa, Physics, and Elementary Particle Physics
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Nuclear and High Energy Physics ,Particle physics ,Limits ,Astrophysics::High Energy Astrophysical Phenomena ,Dark matter ,Capture ,FOS: Physical sciences ,Astrophysics ,South-Pole ,ddc:500.2 ,01 natural sciences ,7. Clean energy ,IceCube ,High Energy Physics - Experiment ,LIMITS ,High Energy Physics - Experiment (hep-ex) ,SOUTH-POLE ,0103 physical sciences ,PARTICLES ,ddc:530 ,Limit (mathematics) ,010306 general physics ,Physics ,High Energy Astrophysical Phenomena (astro-ph.HE) ,Muon ,010308 nuclear & particles physics ,ICE ,Detector ,Ice ,Supersymmetry ,CAPTURE ,Particles ,Physics and Astronomy ,Neutrino detector ,Neutralino ,High Energy Physics::Experiment ,Neutrino ,Astrophysics - High Energy Astrophysical Phenomena - Abstract
A search for an excess of muon-neutrinos from dark matter annihilations in the Sun has been performed with the AMANDA-II neutrino telescope using data collected in 812 days of livetime between 2001 and 2006 and 149 days of livetime collected with the AMANDA-II and the 40-string configuration of IceCube during 2008 and early 2009. No excess over the expected atmospheric neutrino background has been observed. We combine these results with the previously published IceCube limits obtained with data taken during 2007 to obtain a total livetime of 1065 days. We provide an upper limit at 90% confidence level on the annihilation rate of captured neutralinos in the Sun, as well as the corresponding muon flux limit at the Earth, both as functions of the neutralino mass in the range 50 GeV-5000 GeV. We also derive a limit on the neutralino-proton spin-dependent and spin-independent cross section. The limits presented here improve the previous results obtained by the collaboration between a factor of two and five, as well as extending the neutralino masses probed down to 50 GeV. The spin-dependent cross section limits are the most stringent so far for neutralino masses above 200 GeV, and well below direct search results in the mass range from 50 GeV to 5 TeV., author list corrected. Full author list added in this website
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- 2011
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17. First search for atmospheric and extraterrestrial neutrino-induced cascades with the IceCube detector
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F. Clevermann, K. Mase, J. Blumenthal, K. Han, P. O. Hulth, J. Eisch, D. Z. Besson, G. de Vries-Uiterweerd, B. Semburg, Hg Sander, G. W. Sullivan, H. Wissing, N. Kemming, James E. Braun, Daniel Bindig, Olga Botner, C. Pérez de los Heros, M. Krasberg, T. Straszheim, D. J. Boersma, Rasha Abbasi, S. Panknin, A. Piegsa, Nathan Whitehorn, S. Cohen, S. Seunarine, H. Taavola, J. M. Clem, J. M. Joseph, Peter Mészáros, E. Blaufuss, J. C. Davis, P. B. Price, S.J. Lafebre, D. Rutledge, A. Gross, Jon Dumm, M. Prikockis, T. Waldenmaier, T. O. B. Schmidt, Stijn Buitink, S. Yoshida, Joanna Kiryluk, D. Tosi, Ph. Herquet, Timo Karg, Tim Ruhe, M. Walter, A. Rizzo, M. Kowalski, J. Auffenberg, Christian Spiering, O. Depaepe, K. Rawlins, Larissa Paul, S. H. Seo, Gerald Przybylski, R. Morse, M. Danninger, H. S. Matis, K. Hoshina, S. M. Movit, S. Stoyanov, S. Bechet, Kurt Woschnagg, Paul Evenson, L. Koepke, Thomas Meures, Aongus O'Murchadha, T. Fischer-Wasels, Kael Hanson, Justin Vandenbroucke, Henrik J. Johansson, Glenn Spiczak, Albrecht Karle, James Madsen, A. Van Overloop, K. Beattie, Ch. Weaver, M. Labare, T. Griesel, T. Krings, M. Merck, Dmitry Chirkin, T. Kowarik, A. Silvestri, D. Turcan, Francis Halzen, P. Zarzhitsky, A. Schukraft, J. P. Rodrigues, T. Stezelberger, K. Meagher, O. Fadiran, O. Schulz, Chun Xu, J. W. Nam, D. Bose, Alexander Kappes, Martin Wolf, R. C. Bay, Juan Carlos Diaz-Velez, E. A. Strahler, K. Laihem, J. van Santen, K. Wiebe, U. Naumann, Dirk Ryckbosch, Teresa Montaruli, K. Schatto, P. Redl, K. H. Becker, J. J. Beatty, M. Ono, M. V. D'Agostino, G. Kohnen, D. R. Nygren, A. Tamburro, Chad Finley, F. Rothmaier, N. Milke, George Japaridze, Paolo Desiati, D. Berley, G. C. Hill, B. Voigt, J. L. Bazo Alba, Karen Andeen, T. Gluesenkamp, Simona Toscano, S. Odrowski, Xinhua Bai, O. Engdegård, J. Luenemann, K. H. Kampert, N. van Eijndhoven, T. Abu-Zayyad, Matthias Geisler, K. Hultqvist, R. W. Ellsworth, Darren Grant, M. Stamatikos, J. Posselt, Michael J. Baker, L. Demiroers, S. Grullon, M. J. Carson, T. Feusels, Hermann Kolanoski, M. Voge, Pratik Majumdar, Carsten Rott, C. Ha, Elisa Resconi, M. J. Larson, J. L. Kelley, Markus Ahlers, J. Berdermann, A. Marotta, Kirill Filimonov, J. Miller, J. E. Jacobsen, Marcos Santander, M. L. Benabderrahmane, Fabian Kislat, G. Kroll, J. K. Becker, M. Dierckxsens, L. Gerhardt, R. Nahnhauer, J-P Huelss, Reina H. Maruyama, L. Gladstone, P. Roth, A. Goldschmidt, R. Lehmann, M. Bissok, Subir Sarkar, Segev BenZvi, Spencer Klein, D. Seckel, M. Vehring, D. F. Cowen, R. Porrata, M. M. Foerster, Paraic A. Kenny, Juanan Aguilar, Anatoli Fedynitch, J. C. Gallagher, Takao Kuwabara, D. Bertrand, A. Franckowiak, Xianwu Xu, R. Ehrlich, B. Christy, G. Stephens, A. Olivas, A. Ishihara, Allan Hallgren, C. Bohm, S. Westerhoff, A. R. Fazely, O. Tarasova, Tyce DeYoung, Samvel Ter-Antonyan, S. Hussain, Sandro Kopper, D. J. Koskinen, A. Slipak, S. Tilav, P. A. Toale, A. Schultes, Kara Hoffman, D. Heinen, C. Colnard, H. Landsman, P. Niessen, S. Boeser, Yolanda Sestayo de la Cerra, J. Dreyer, I. Taboada, Y. Abdou, M. Wallraff, M. Gurtner, Wolfgang Rhode, R. J. Lauer, C. De Clercq, B. D. Fox, P. Berghaus, S. Euler, A. Homeier, David A. Williams, Damian Pieloth, D. Hubert, A. M. Brown, S. W. Barwick, Christopher Wiebusch, Todor Stanev, C. Wendt, J. Daughhetee, F. Descamps, J-H Koehne, A. Tepe, R. Franke, C. Walck, Thomas K. Gaisser, G. B. Yodh, Q. Swillens, B. Ruzybayev, W. Huelsnitz, K. Helbing, E. Middell, Elisa Bernardini, M. Ribordy, M. Schunck, Jenni Adams, K. Kuehn, S. Hickford, A. Schoenwald, R. G. Stokstad, R. Wischnewski, J. Petrovic, M. Olivo, and J. A. Goodman
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HIGH-ENERGY NEUTRINOS ,SELECTION ,Nuclear and High Energy Physics ,Astrophysics::High Energy Astrophysical Phenomena ,High-energy neutrinos ,FOS: Physical sciences ,Flux ,Cosmic ray ,Elementary particle ,Astrophysics ,Particle detector ,IceCube ,High Energy Physics - Experiment ,High Energy Physics - Experiment (hep-ex) ,SCATTERING ,ddc:530 ,High Energy Astrophysical Phenomena (astro-ph.HE) ,Physics ,SPECTRUM ,ICE ,High Energy Physics::Phenomenology ,Massless particle ,Physics and Astronomy ,Neutrino detector ,AMANDA-II ,High Energy Physics::Experiment ,Neutrino ,Astrophysics - High Energy Astrophysical Phenomena ,Lepton - Abstract
We report on the first search for atmospheric and for diffuse astrophysical neutrino-induced showers (cascades) in the IceCube detector using 257 days of data collected in the year 2007-2008 with 22 strings active. A total of 14 events with energies above 16 TeV remained after event selections in the diffuse analysis, with an expected total background contribution of $8.3\pm 3.6$. At 90% confidence we set an upper limit of $E^2\Phi_{90%CL}, Comment: 14 pages, 16 figures
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- 2011
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18. Measurement of acoustic attenuation in South Pole ice
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A. Piegsa, P. Roth, L. Gustafsson, J. L. Kelley, K.-H. Becker, Markus Ahlers, Larissa Paul, P. O. Hulth, J. Eisch, K. Kuehn, K. Beattie, Albrecht Karle, O. Schulz, K. Meagher, T. Krings, K. Mase, Christian Spiering, R. Porrata, G. de Vries-Uiterweerd, E. A. Strahler, A. Schukraft, Delia Tosi, S. Hussain, Timo Karg, B. Semburg, S. Knops, Justin Vandenbroucke, J. H. Koehne, Samvel Ter-Antonyan, P. B. Price, Gerald Przybylski, Dirk Ryckbosch, F. Clevermann, C. Pérez de los Heros, A. Gross, Dirk Lennarz, Hermann Kolanoski, H. Wissing, A. Schultes, J. M. Clem, Jon Dumm, M. Prikockis, T. Waldenmaier, Joanna Kiryluk, D. J. Boersma, A. Van Overloop, J. J. Beatty, J. P. Rodrigues, Dj. Koskinen, T. Stezelberger, T. O. B. Schmidt, C. Ha, M. Kowalski, J. P. Yanez, Henrik J. Johansson, M. L. Benabderrahmane, M. Danninger, P. Berghaus, S. Grullon, M. J. Carson, S. Panknin, Kurt Woschnagg, F. Rothmaier, Paul Evenson, G. W. Sullivan, S.J. Lafebre, A. Silvestri, S. Euler, M. Stamatikos, Fabian Kislat, Matthias Geisler, K. Hultqvist, N. Kemming, James E. Braun, Darren Grant, H. Landsman, Paraic A. Kenny, Juanan Aguilar, Takao Kuwabara, T. Kowarik, B. Christy, A. Tamburro, B. Voigt, Anna Franckowiak, Xinhua Bai, W. Huelsnitz, K. Helbing, Christopher Wiebusch, Dmitry Chirkin, M. V. D'Agostino, K. Schatto, J. Posselt, G. Kohnen, Damian Pieloth, M. Ono, D. Hubert, G. Wikström, T. Griesel, A. Ishihara, Thomas Meures, Karen Andeen, M. Merck, Alexander Kappes, A. Goldschmidt, J. L. Bazo Alba, J. Luenemann, Yolanda Sestayo de la Cerra, L. Demiroers, K. Wiebe, G. Stephens, S. Westerhoff, R. Nahnhauer, T. Feusels, K. Hoshina, L. Koepke, T. Abu-Zayyad, O. Tarasova, K. Han, J. E. Jacobsen, Glenn Spiczak, Pratik Majumdar, J. K. Becker, Reina H. Maruyama, Carsten Rott, L. Gerhardt, R. Ehrlich, M. Matusik, T. Gluesenkamp, Spencer Klein, Tim Ruhe, M. Walter, A. Rizzo, U. Naumann, Olga Botner, A. Olivas, R. W. Ellsworth, M. Bissok, M. M. Foerster, B. Ruzybayev, R. Ganugapati, Laura C. Bradley, E. Blaufuss, M. R. Duvoort, J. C. Gallagher, D. F. Cowen, Kara Hoffman, R. L. Imlay, S. H. Seo, Xianwu Xu, O. Depaepe, S. Stoyanov, Allan Hallgren, C. Bohm, S. M. Movit, K. Laihem, N. Milke, George Japaridze, David A. Schneider, O. Engdegård, D. Berley, G. C. Hill, Michael J. Baker, Elisa Resconi, P. Niessen, L. Gladstone, J. Berdermann, H. S. Matis, D. Seckel, S. Boeser, S. Tilav, I. Taboada, Wolfgang Rhode, A. R. Fazely, Tyce DeYoung, P. A. Toale, R. C. Bay, M. Labare, T. Straszheim, J. van Santen, Juan Carlos Diaz-Velez, D. Turcan, J. Dreyer, Y. Abdou, S. Bechet, Francis Halzen, P. Redl, P. Zarzhitsky, J. W. Nam, J. P. Huelss, O. Fadiran, Karl-Heinz Kampert, H. G. Sander, Kirill Filimonov, D. R. Nygren, S. Odrowski, Chun Xu, J. M. Joseph, Rasha Abbasi, Peter Mészáros, Stijn Buitink, R. Morse, B. D. Fox, D. Bertrand, M. Wallraff, M. Gurtner, C. Roucelle, D. Z. Besson, Nathan Whitehorn, S. Cohen, J. Auffenberg, Chad Finley, C. Colnard, Jenni Adams, Subir Sarkar, S. Hickford, R. G. Stokstad, R. Wischnewski, J. Petrovic, R. M. Gunasingha, A. Slipakaj, R. J. Lauer, M. Olivo, J. A. Goodman, C. De Clercq, David A. Williams, M. Krasberg, S. W. Barwick, Q. Swillens, S. Yoshida, E. Middell, Elisa Bernardini, N. van Eijndhoven, M. Ribordy, S. Schlenstedt, G. Kroll, Todor Stanev, C. Wendt, R. Lehmann, F. Descamps, Ph. Herquet, A. Tepe, R. Franke, Kael Hanson, C. Walck, Thomas K. Gaisser, G. B. Yodh, Paolo Desiati, S. Seunarine, D. Rutledge, K. Rawlins, James Madsen, A. Homeier, Teresa Montaruli, M. Schunck, Max-Planck-Institut für Kernphysik (MPIK), Max-Planck-Gesellschaft, APC - Cosmologie, AstroParticule et Cosmologie (APC (UMR_7164)), Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3), Dept. of Physics, University of Wisconsin-Madison, Dept. of Subatomic and Radiation Physics, University of Gent, Department of Physics and Astronomy [Tuscaloosa), University of Alabama [Tuscaloosa] (UA), University of Oxford [Oxford], University of Wuppertal, University of Delaware [Newark], Department of Physics and Astronomy [Irvine], University of California [Irvine] (UCI), University of California-University of California, University of California, Ohio State University [Columbus] (OSU), Dept. of Astronomy, Science Faculty CP230, Université libre de Bruxelles (ULB), University of Maryland [College Park], University of Maryland System-University of Maryland System, Dept. of Physics and Astronomy, University of Kansas [Lawrence] (KU), Rheinisch-Westfälische Technische Hochschule Aachen (RWTH), Stockholm University, Rheinische Friedrich-Wilhelms-Universität Bonn, Department of Physics and Astronomy [Uppsala], Uppsala University, University Park, Technische Universität Dortmund [Dortmund] (TU), École Polytechnique Fédérale, Department of Astronomy and Astrophysics [PennState], Pennsylvania State University (Penn State), Penn State System-Penn State System, Vrije Universiteit Brussel (VUB), Department of Physics and Astronomy [Utrecht], Utrecht University [Utrecht], Southern University, Humboldt-Universität zu Berlin, Department of Physics [Edmonton], University of Alberta, University of Mainz, Johannes Gutenberg - Universität Mainz (JGU), Department of Physics and Astronomy [Christchurch] (DPA), University of Canterbury [Christchurch], Université de Mons (UMons), Chiba University, University of Alaska [Anchorage], University of the West Indies, Georgia Institute of Technology [Atlanta], Physique Corpusculaire et Cosmologie - Collège de France (PCC), Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Collège de France (CdF)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-AstroParticule et Cosmologie (APC (UMR_7164)), Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Observatoire de Paris, PSL Research University (PSL)-PSL Research University (PSL)-Université Paris Diderot - Paris 7 (UPD7), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Institut National de Physique Nucléaire et de Physique des Particules du CNRS (IN2P3)-Observatoire de Paris, and Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Université Paris Diderot - Paris 7 (UPD7)-Centre National de la Recherche Scientifique (CNRS)
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Acoustic attenuation ,Acoustics ,Ice ,Neutrino astronomy ,South Pole ,[PHYS.ASTR.HE]Physics [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE] ,010504 meteorology & atmospheric sciences ,[SDU.ASTR.CO]Sciences of the Universe [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] ,ice ,FOS: Physical sciences ,Aetiology, screening and detection [ONCOL 5] ,Lambda ,01 natural sciences ,neutrino astronomy ,[PHYS.ASTR.CO]Physics [physics]/Astrophysics [astro-ph]/Cosmology and Extra-Galactic Astrophysics [astro-ph.CO] ,Optics ,Spectrum ,0103 physical sciences ,acoustics ,Instrumentation and Methods for Astrophysics (astro-ph.IM) ,0105 earth and related environmental sciences ,Physics ,010308 nuclear & particles physics ,business.industry ,Attenuation ,[SDU.ASTR.HE]Sciences of the Universe [physics]/Astrophysics [astro-ph]/High Energy Astrophysical Phenomena [astro-ph.HE] ,Transmitter ,Attenuation length ,Astronomy and Astrophysics ,Geodesy ,Amplitude ,Attenuation coefficient ,ddc:540 ,Neutrino ,Astrophysics - Instrumentation and Methods for Astrophysics ,business ,acoustic attenuation - Abstract
Using the South Pole Acoustic Test Setup (SPATS) and a retrievable transmitter deployed in holes drilled for the IceCube experiment, we have measured the attenuation of acoustic signals by South Pole ice at depths between 190 m and 500 m. Three data sets, using different acoustic sources, have been analyzed and give consistent results. The method with the smallest systematic uncertainties yields an amplitude attenuation coefficient alpha = 3.20 \pm 0.57 km^(-1) between 10 and 30 kHz, considerably larger than previous theoretical estimates. Expressed as an attenuation length, the analyses give a consistent result for lambda = 1/alpha of ~1/300 m with 20% uncertainty. No significant depth or frequency dependence has been found., Comment: 17 pages, 12 figures, published in Astroparticle Physics, 2010
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- 2011
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19. Search for dark matter from the Galactic halo with the IceCube neutrino telescope
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Christian Spiering, C. Ha, M. L. Benabderrahmane, Justin Vandenbroucke, Albrecht Karle, B. D. Fox, Paraic A. Kenny, Juanan Aguilar, K. Meagher, Takao Kuwabara, T. Straszheim, B. Christy, J. J. Beatty, Martin Wolf, A. Ishihara, John Clem, M. Labare, Peter Mészáros, J. Posselt, P. Niessen, Anatoli Fedynitch, A. Piegsa, A. Marotta, Reina H. Maruyama, Segev BenZvi, Rasha Abbasi, Spencer Klein, S. Boeser, I. Taboada, T. Denger, H. Taavola, Aongus O'Murchadha, W. Huelsnitz, J. L. Kelley, Markus Ahlers, N. van Eijndhoven, G. Stephens, S. Westerhoff, M. Dierckxsens, M. Stüer, R. J. Lauer, C. De Clercq, E. Blaufuss, J. C. Davis, J. P. Huelss, K. Helbing, O. Tarasova, L. Demiroers, D. Bertrand, K. H. Kampert, M. Stamatikos, R. Porrata, P. B. Price, T. O. B. Schmidt, D. Berley, G. C. Hill, G. Kroll, David A. Williams, Kara Hoffman, N. Milke, George Japaridze, H. S. Matis, Samvel Ter-Antonyan, Michael J. Baker, D. Heinen, C. Colnard, Kurt Woschnagg, Tim Ruhe, M. Walter, D. Turcan, Francis Halzen, P. Zarzhitsky, O. Fadiran, L. Gladstone, Timo Karg, M. Schunck, A. Goldschmidt, A. Schultes, Jon Dumm, D. Seckel, M. Voge, Paul Evenson, M. Wallraff, M. Gurtner, J. Auffenberg, Dmitry Chirkin, M. Prikockis, T. Waldenmaier, Joanna Kiryluk, M. Kowalski, A. R. Fazely, Tyce DeYoung, P. A. Toale, O. Engdegård, A. Van Overloop, D. Bose, Alexander Kappes, Elisa Resconi, K. Kuehn, S. H. Seo, M. Danninger, Wolfgang Rhode, Ch. Weaver, F. Rothmaier, Matthias Geisler, K. Hultqvist, Darren Grant, S. M. Movit, J. Berdermann, T. Kowarik, Karen Andeen, K. Beattie, O. Schulz, Chad Finley, S. W. Barwick, C. Pérez de los Heros, A. Tamburro, B. Voigt, J. Petrovic, Xinhua Bai, M. Ono, K. Rawlins, P. Roth, J. L. Bazo Alba, P. Berghaus, M. Krasberg, James Madsen, J. Luenemann, D. Z. Besson, S. Euler, T. Griesel, T. Feusels, T. Abu-Zayyad, K. Wiebe, Q. Swillens, Damian Pieloth, B. Ruzybayev, D. Hubert, A. M. Brown, Pratik Majumdar, J. E. Jacobsen, Marcos Santander, L. Gerhardt, A. Rizzo, Teresa Montaruli, O. Depaepe, S. Stoyanov, S. Yoshida, M. Vehring, D. F. Cowen, A. Slipak, S. Tilav, Nathan Whitehorn, S. Cohen, R. Nahnhauer, A. Homeier, S. Bechet, Christopher Wiebusch, R. C. Bay, P. Redl, Todor Stanev, C. Wendt, K.-H. Becker, Juan Carlos Diaz-Velez, F. Descamps, J. Daughhetee, A. Tepe, Kirill Filimonov, T. Fischer-Wasels, A. Schukraft, K. Laihem, J. H. Koehne, R. Franke, C. Walck, F. Clevermann, Dirk Ryckbosch, Thomas K. Gaisser, G. B. Yodh, P. O. Hulth, J. Eisch, J. K. Becker, G. de Vries-Uiterweerd, S. Seunarine, G. W. Sullivan, James E. Braun, D. Rutledge, Carsten Rott, B. Semburg, J. Miller, M. Bissok, Ph. Herquet, Xianwu Xu, C. Bohm, H. Wissing, M. M. Foerster, J. C. Gallagher, Daniel Bindig, Kael Hanson, J. van Santen, Allan Hallgren, Sandro Kopper, Paolo Desiati, J. P. Rodrigues, T. Stezelberger, A. Gross, J. Dreyer, Y. Abdou, M. V. D'Agostino, A. Silvestri, M. Olivo, J. A. Goodman, K. Mase, Subir Sarkar, E. Middell, Elisa Bernardini, M. Ribordy, Jenni Adams, S. Hickford, A. Schoenwald, R. G. Stokstad, R. Wischnewski, S. Panknin, J. W. Nam, J. M. Joseph, D. R. Nygren, S. Odrowski, Thomas Meures, S. Grullon, M. J. Carson, M. J. Larson, M. Merck, Fabian Kislat, A. Franckowiak, Stijn Buitink, K. Hoshina, L. Koepke, Glenn Spiczak, R. Morse, U. Naumann, T. Gluesenkamp, Simona Toscano, S. Hussain, D. J. Koskinen, R. W. Ellsworth, D. J. Boersma, S.J. Lafebre, H. G. Sander, Chun Xu, Henrik J. Johansson, R. Ehrlich, A. Olivas, H. Landsman, K. Schatto, G. Kohnen, Yolanda Sestayo de la Cerra, T. Krings, E. A. Strahler, Hermann Kolanoski, D. Tosi, Gerald Przybylski, J. Blumenthal, K. Han, Olga Botner, and Larissa Paul
- Subjects
Nuclear and High Energy Physics ,Astrophysics::High Energy Astrophysical Phenomena ,Dark matter ,Astrophysics::Cosmology and Extragalactic Astrophysics ,Astrophysics ,01 natural sciences ,IceCube ,Galactic halo ,0103 physical sciences ,ddc:530 ,010306 general physics ,Astrophysics::Galaxy Astrophysics ,Physics ,010308 nuclear & particles physics ,Gamma-Ray Emission ,Hot dark matter ,Astronomy ,Cosmic-Rays ,Dark matter halo ,Particles ,Neutrino detector ,Anisotropy ,High Energy Physics::Experiment ,Halo ,Dwarf Spheroidal Galaxies ,Neutrino ,Neutrino astronomy - Abstract
Self-annihilating or decaying dark matter in the Galactic halo might produce high energy neutrinos detectable with neutrino telescopes. We have conducted a search for such a signal using 276 days of data from the IceCube 22-string configuration detector acquired during 2007 and 2008. The effect of halo model choice in the extracted limit is reduced by performing a search that considers the outer halo region and not the Galactic Center. We constrain any large-scale neutrino anisotropy and are able to set a limit on the dark matter self-annihilation cross section of ⟨σAv⟩≃10-22 cm3 s-1 for weakly interacting massive particle masses above 1 TeV, assuming a monochromatic neutrino line spectrum., Physical Review D ; Volume 84, Issue 2
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- 2011
- Full Text
- View/download PDF
20. Clerical Attitudes to Primary Education in July Monarchy France, 1833-1848 (Abstract)
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Robert L. Koepke, Robert L. Koepke, Robert L. Koepke, and Robert L. Koepke
- Abstract
Journal of the Western Society for French History: vol. 21, (dlps) 0642292.0021.052, http://hdl.handle.net/2027/spo.0642292.0021.052, This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 3.0 License. Please contact mpub-help@umich.edu to use this work in a way not covered by the license.
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- 1993
21. Performance of the ATLAS Hadronic End-Cap Calorimeter in Beam Tests
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Vladimir Sulin, T. A. Hodges, R. Langstaff, Andrei Akimov, Christian Zeitnitz, W. Haberer, M.L. Levitsky, D. C. O'Neil, Manuella Vincter, V.V. Sytnik, W. Tribanek, C. Sbarra, M. Yakimenko, A. Jusko, S. N. Shilov, F. Toevs, James Pinfold, Eduard Kladiva, H. Brettel, M. Aderholz, H. P. Wellisch, A. Neganov, U. Schaefer, H. Laskus, M. Lindenmayer, J. Huber, Rachid Mazini, C. J. Oram, Margret Fincke-Keeler, Evgueni Ladygin, R. Huber, A. Karev, M. Rosvick, M. Speransky, S. Kakurin, E. W. Pattyn, R. Othegraven, Yu. A. Usov, G. Y. Mitrofanov, W. Walkowiak, A. A. Minaenko, J. Soukup, P. Mooshofer, I.L. Pisarev, R. Mehdiyev, Karl Jakobs, S. Hiebel, Aston Komar, B. Dowler, W D Cwienk, J. Thadome, S. P. Denisov, P. M. Mockett, A. B. Lazarev, M. Y. Kazarinov, E. Serochkin, A. Honma, A. Shalyugin, M. Hohlfeld, L. Kurchaninov, M. Lenckowski, Richard Keeler, M. Wielers, H. M. Braun, R. Chytracek, Hasko Stenzel, Claude Leroy, Peter Schacht, Sergey Chekulaev, A. Fedorov, Jibu P. Thomas, A. Pleskatch, Andrey Kiryunin, T. Kobler, Denis Salihagic, P. Birney, K. W. Hoyle, D. Striegel, Namig Javadov, D. Fortin, D. A. Forbush, Robert McPherson, R. Maharaj, Andrei Snesarev, M. Blagov, Dusan Bruncko, E. Marschalkowski, J. Bán, Pavol Strizenec, L. Koepke, B. Dulny, J. Fent, M. Lefebvre, D. Meder, A.M. Moiseev, M. Dobbs, Alexander Cheplakov, A. Fischer, V. Gaertner, V. Kalinnikov, Vladimir Datskov, Horst Oberlack, P. Benoit, and Victor Kukhtin
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Physics ,Nuclear and High Energy Physics ,Range (particle radiation) ,Particle physics ,Large Hadron Collider ,Calorimeter (particle physics) ,Physics::Instrumentation and Detectors ,Linear particle accelerator ,Nuclear physics ,medicine.anatomical_structure ,Pion ,Atlas (anatomy) ,medicine ,Measuring instrument ,Physics::Accelerator Physics ,High Energy Physics::Experiment ,Detectors and Experimental Techniques ,Nuclear Experiment ,Instrumentation ,Beam (structure) - Abstract
Modules of the ATLAS liquid argon Hadronic End-cap Calorimeter (HEC) were exposed to beams of electrons, muons and pions in the energy range 6⩽ E ⩽200 GeV at the CERN SPS. A description of the HEC and of the beam test setup are given. Results on the energy response and resolution are presented and compared with simulations. The ATLAS energy resolution for jets in the end-cap region is inferred and meets the ATLAS requirements.
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- 2001
22. Macrophages and their subpopulations following allogenic bone marrow transplantation for chronic myeloid leukaemia
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Hans Michael Kvasnicka, U. W. Schaefer, P. Wenzel, D. W. Beelen, Juergen Thiele, M. L. Koepke, and L D Leder
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Adult ,Male ,Pathology ,medicine.medical_specialty ,Population ,Medizin ,Antigens, Differentiation, Myelomonocytic ,Pathology and Forensic Medicine ,Reticular cell ,Antigens, CD ,Bone Marrow ,Leukemia, Myelogenous, Chronic, BCR-ABL Positive ,Macrophage ,Medicine ,Humans ,Transplantation, Homologous ,Postoperative Period ,education ,Molecular Biology ,Histiocyte ,Bone Marrow Transplantation ,education.field_of_study ,CD68 ,business.industry ,Macrophages ,Cell Biology ,General Medicine ,Haematopoiesis ,medicine.anatomical_structure ,Immunology ,Erythropoiesis ,Female ,Bone marrow ,business - Abstract
A morphometric and immunohistochemical study was performed on 354 bone marrow trephine biopsies derived from 126 patients with chronic myeloid leukaemia (CML) before and after allogeneic bone marrow transplantation (BMT). The purpose of this investigation was to evaluate the macrophage population, including several subsets and their dynamics in the posttransplant period. In addition to the total CD68+ resident (mature) macrophages the so-called activated fraction identified by its capacity to express alpha-D-galactosyl residues, the pseudo-Gaucher cells (PGCs) and the iron-laden histiocytic reticular cells were also considered. Following immuno- and lectin-histochemical staining morphometric analysis was carried out on sequential postgraft bone marrow specimens at standardized intervals. Compared to the normal bone marrow and calculated per haematopoiesis (cellularity) an overall decrease of about 40-50% in the quantity of CD68+ macrophages and the BSA-I+ subpopulation was detectable in the early posttransplant period (9-45 days after BMT). Noteworthy was the temporal recurrence of PGCs in the engrafted bone marrow, which was not associated with a clonally transformed cell population or leukaemic relapse. Reappearance of postgraft PGCs was most prominent in the first 2 months after BMT. This conspicuous feature was presumed to be functionally associated with a pronounced degradation of cell debris following pretransplant myelo-ablative therapy (scavenger macrophages). Evidence for an activation of the BSA-I+ macrophage subset was derived from the identical carbohydrate-binding capacity shown by the PGCs. In the regenerating haematopoiesis shortly after BMT a significant correlation between the number of BSA-I+ macrophages and erythroid precursor cells was determinable. This result implicates a close functional relationship between postgraft reconstitution of erythropoietic islets and centrally localized activated macrophages. In conclusion, findings emerging from this study included the reappearance of PCGs in the engrafted bone marrow independently of a leukaemic relapse and the significant association of the activated BSA-I+ macrophage subset with the recovery of erythropoiesis.
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- 2000
23. ATLAS DETECTOR AND PHYSICS PERFORMANCE TECHNICAL DESIGN REPORT
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John Baines, T. Yang, J. Dodd, J-M. Noppe, S. Meuser, T. Embry, Ludovico Pontecorvo, V. V. Lapin, Alexander Cheplakov, S. P. Baranov, S. R. Hou, S. Errede, Valerio Vercesi, D. J. Schotanus, M. Keil, J. Stastny, H. Wellenstein, V.V. Gilevsky, W. J. Murray, I. A. Pless, Pavol Strizenec, J. Salt, V. A. Korotkov, Peter Jenni, M. Tadel, F. Tang, E. Sayouty, F. Rossel, J. M. Butterworth, W. Burris, M. El Kacimi, Akira Yamamoto, Ph. Demierre, Polina Kuzhir, Y. Jacquier, D. Hayes, A. Krivchitch, S. W. O'Neale, H. Ten Kate, F. Waldner, Petr Sicho, F. M. Newcomer, G. Chiefari, Jianqiao Ye, G. Lehmann, M. A. Dobbs, Yu.A. Khokhlov, Francesco Spanò, L. Holm, K. J. Anderson, H. Drevermann, Ph Martin, D.J. Martin, A. Atag, S. M. Fisher, H. van der Bij, Odette Benary, Mihai Caprini, C. Brouwer, M. Holder, M. Franklin, F. E. Taylor, P.R. Turner, Sam Daniel Mullin, G. Sette, V.A. Onuchin, J. Sorokina, Joleen Pater, Hiroshi Sakamoto, V.I. Sirotenko, Simon George, P. G. Estabrooks, R. K. Keeler, D. Glenzinsky, A. Astvatsaturov, Takahiko Kondo, L. S. Peak, A. G. Clark, Yu. Merzlyakov, F. Crijns, B. Canton, H. J. Burckhart, Jacqueline Batley, K. Jon-And, M. Vassiliou, D. Bocian, F. Haug, Sp. Dedoussis, J. J. Thaler, Rupert Leitner, M. Tyndel, Osamu Sasaki, V. Filimonov, P. Stassi, D. Kuhn, M. Spitalieri, F. Zuffranieri, J. Hrivnac, John Hart, Yu.I. Salomatin, A. Lebedev, G. Blanchot, David Francis, Marcello Fanti, A.G. Shamov, Stefan Koperny, Susanne Kersten, Theodora Papadopoulou, B. Kaan, G. Reinmuth, Kaushik De, B. Yang, L. Tuura, R. Hashemi-Nezhad, J. Pouxe, Th. Baer, A. Kerr, Uwe Bratzler, O. Martin, Patrick Fassnacht, J. M. Lopez, D. Calvet, G. Martin-Chassard, Vincent Hedberg, D. Sopromadze, Sylvain Fichet, A. Ferrer, Serge Smirnov, T. Lari, C. Zeitnitz, B. Dulny, M.V. Kuzmin, T. Kohriki, Vasiliki A Mitsou, P. M. Watkins, Elemer Nagy, M. Wunsch, R. J. Cashmore, Fridolin Dittus, V.V. Bryzgalov, D. Axen, Stephane Jezequel, Tomas Davidek, Edward Diehl, D. Breton, Shlomo Dado, B. Nicquevert, Bengt Lund-Jensen, L. Gustafsson, A. N. Sissakian, B. G. Pope, Daniel Lellouch, Laurent Vacavant, K. Hashemi, R. Beccherle, A.M. Lee, J. Fent, H. Schuijlenburg, A. Onofre, J. M. Crespo, M. Cambiaghi, T. Hansl-Kozanecka, V. V. Tokmenin, Andreas Petridis, M. Cailles, Anna Zuzana Dubnickova, Vitaliano Chiarella, H. A. Neal, Y. Iwata, K. Zitek, A. Perus, D. Bintinger, H.J. Rzayev, J. Ludvig, M. L. Ferrer, Henry Lubatti, Alexi Gongadze, Giovanni Darbo, P. N. Ratoff, J. F. Martin, D. Fasssouliotis, Paolo Camarri, Stefan Tapprogge, J. Vanko, A. Maio, Cheng Chen, Sylvain Tisserant, Sk Noor Alam, S. Rizek, S. Cologna, Yu. Gouz, A. V. Akimov, A. Artamonov, Jolanta Olszowska, D. Manjavidze, Andrej Filipcic, B. Rolker, Georges Azuelos, Alberto Aloisio, Krzysztof Piotrzkowski, A. Greenall, H. Groenstege, C. Mayri, V. M. Malyshev, Helmut Vincke, Barry King, F. Alessandria, B. Thooris, J. Drees, I. O. Skillicorn, Z. Metreveli, Veljko Radeka, Thomas Trefzger, T. Liu, P. Rosinsky, H. Wahlen, J. Proudfoot, V. Snyatkov, D.G. Ebling, J. Ludwig, Lidia Smirnova, Laurent Chevalier, R. Arsenescu, A. Tchountonov, I. Tsoukerman, Javier Lozano, Ian Hinchliffe, A. Di Ciaccio, C. Hebrard, Evgeny Starchenko, K. Runge, T. Dubbs, B. Athar, A. Airapetian, W. Heubers, Z. Khorguashvili, A. Chekhtman, K. Mahboubi, J. Silva, Kiyotomo Kawagoe, M. Kucera, G. Hughes, Bianca Osculati, V. Grabsky, R. Yoshida, J.L. Beney, R. E. Hughes-Jones, Ryuichi Takashima, M. Jirina, M. Mencik, W. Ockenfels, F. Gianotti, N. D. Topilin, N. A. McCubbin, V. Soergel, K. Pretzl, B. Zhang, Martin Hoeferkamp, Alexander Borissov, Evangelos Gazis, S.C. Timm, I.E. Chirikov-Zorin, Petr Tas, S. H. Oh, S. Leven, Alan Poppleton, J. Weichert, R. Tirler, S. A. Robins, Yoshio Arai, Claude Guyot, I. Stekl, F. Kong, Bertrand Laforge, K. H. Becks, Leonardo Paolo Rossi, A. Liolios, E. Marschalkowski, John H. L. Hansen, P. Schwemling, S. Kullander, V. Kovtun, Marina Cobal, Oleg Fedin, O. Boyle, Elizabeth H. Simmons, Calin Alexa, Driss Goujdami, V. Koshtoev, James Shank, F. Dydak, Oscar Blanch, Barbara Liberti, Z. Tomiak, D. Prokofiev, Jianming Qian, A. Moreton, E. Vigeolas, B. Repetti, Georg Zobernig, A. Koutchenkov, C. Weber, S. Jarp, Yoji Hasegawa, M. Seman, G. Lutz, T. Haelen, J. C. Hill, Irinel Caprini, M. Hass, L. Micu, B. Scuri, D. Striegel, Martine Bosman, E. Hazen, F. Combley, A. Breskin, Margherita Primavera, T. Emura, B. Gallet, Francesco Ragusa, P. Malecki, G. D. Kekelidze, A. Amadon, H. Simmler, Paul Hanke, P. de Girolamo, A. Nichols, M. Chardalas, Samuel Silverstein, C. N. Booth, G. D. Alexeev, Flera Rizatdinova, Stefano Veneziano, B. Lorstad, Ketevi Assamagan, B. Dinkespiler, M Mandl, L. Zanello, Sally Seidel, G. D. Hallewell, R. Davisson, C. Conta, Yuehong Xie, Klaus Hamacher, M. Hess, Tatiana Klioutchnikova, M. Maneira, S. Zeldovich, A. Manabe, A. Konstantinov, T. Grigalashvili, E. Rulikowska-Zarebska, Oliver Keith Baker, F. Chollet-LeFlour, J-F. Grivaz, S. D. Kolya, D. Makowiecki, Luc Poggioli, Christine Kourkoumelis, R. Hamatsu, I. A. Gaponenko, G. Crone, G. Ridolfi, M. Ziolkowski, H. Korsmo, Livio Mapelli, N. Hill, J. Kotcher, A. Pozzo, R. W. L. Jones, A. Rudge, V. Senchishin, Laura Perini, V. Zaitsev, Victor Maleev, Armen Vartapetian, G. Passardi, G. Kieft, Karl Jakobs, O. Celik, A. Astbury, J. R. Carter, J. Hobbs, Yoshiji Yasu, F. Ballester, N. Cartiglia, A. Andreazza, Yoram Rozen, O. Bystrom, Mauro Iodice, Tord Ekelof, S. V. Mouraviev, Dirk Zerwas, D. H. Saxon, P. P. Allport, Nigel Hessey, F. Luehring, J. Ban, S. Basiladze, R. Stanek, Daniel Froidevaux, J. W. Chapman, Vadim Gratchev, H. L. Li, Frank Paige, V. Zhuravlev, V. V. Glagolev, T. Mouthuy, Bruno Mansoulie, N. K. Watson, H. Meinhard, S-O. Holmgren, P. J. Hendriks, P. Morettini, Remi Lafaye, Maria Smizanska, F. Broggi, Maia Mosidze, W. Kozanecki, G. Mace, S. Patricelli, T. O. Niinikoski, M. Kollegov, R. Carrasco, A. Bogush, Michal Suk, T. W. Pritchard, S. Patritchev, R. Zitoun, Marcella Capua, I. Shein, J. V. Dawson, Sanchita Bhadra, L. Azhgirei, D. Akerman, S. Kruchinin, J. Boniface, S. Wheeler, A. Masserot, C. H. Wang, S. V. Kopikov, Mikhail Kirsanov, J.B. Romance, P. Kyberd, S. P. Ahlen, P. Le Du, Alessandro Paoloni, C. Arnault, Speranza Falciano, G.A. Blair, R. Suglia, P. Gorbunov, Fernando Barreiro, P. Puzo, Giosuè Costa, J. Prast, M. Chalifour, D. V. Dedovich, M. Pepe-Altarelli, Jeffrey D Steinberg, Joaquin Santander, R. A. McLaren, Ole Røhne, L.E. Kirsh, Claus Goessling, D. Newman-Coburn, Edward May, C. Haber, Junichi Kanzaki, Joao Seixas, Leonardo Merola, G. Vegni, D. Zontar, G. A. Chelkov, R. Richter, H. O. Danielsson, N. Yamdagni, J. Blocki, H. Boterenbrood, Glen A. Evans, S.P. Konovalov, S. W. Snow, W. Bonivento, Enrique J. Fernández, G. Mirabelli, R. S. Orr, Alexander Lincoln Read, K. Bos, T. J. Sloan, Luiz Caloba, M. Stavrianakou, I.S. Satsunkevich, Ralf P. Richter, Sten Hellman, J. T. Fraser, Mogens Dam, N. A. Smith, Paola Sala, Lei Zhang, J. Snow, Jan Jakubek, C. Chollet, R. Salukvadze, M.L. Levitsky, Michael Rijssenbeek, T. Stockmanns, V. G. Zaets, M. Nikolenko, B. Renk, J. Zhao, M.J. Varanda, B. M. Hawes, B. Pineiro, N. Juravlev, A. DiMattia, D. G. Charlton, F. Constantin, R. Cranfield, J.A. Dijkema, V. Dodonov, D. C. Bailey, A. Semenov, A. De Angelis, C. Rabier, J. Koehler, Andrea Negri, V.N. Mikhailin, Dugan O'Neil, G.F. Moorhead, L. Chikovani, F. Marzano, K. Merle, P. Creti, S. González de la Hoz, T-Y. Chen, Jordan Martins, J.J. Mares, I. P. Duerdoth, M Morrissey, A. G. Frodesen, J. R. Bensinger, Yu. Sedykh, Yu. Tsyupa, B. Van Eijk, H. Takeda, Jozef Ferencei, G. C. Barrand, B. A. Khomenko, C.W. Fabjan, E. Anderssen, N. Graf, M. Dobson, Gokhan Unel, R. Othegraven, B. Merkel, Richard Brenner, L. Gabunia, V. Pancheluga, Igor Gavrilenko, Pavel P. Povinec, V. Anosov, W. J. Robertson, D. Levin, Roberto Cardarelli, V.S. Panin, F. Daudon, G. Comes, A. Scheltckov, Val O'Shea, I. Mandjavidze, M. Fortner, Q. Ouyang, J. G. Loken, G.-J. Pols, C. Lesmond, T. Medcalf, Dario Barberis, Horst Oberlack, M. Huet, G. P. Benincasa, A. Filippas, C. A. Heusch, C.K. Jung, P. S. Marrocchesi, Alessandra Ciocio, K. Sliwa, J. T. Linnemann, S. Klimenko, Peter Schmid, J. Stanicek, Arnaud Ferrari, K. Tittel, D. Fasching, M. Blaquiere, Konrad Kleinknecht, R. Maenner, J-J. Veillet, D. Shabalin, S.E. Willis, B.T. Payne, A. Fernandez, Petre Dita, Yu.F. Lomakin, A. Ulvi Yilmazer, M. Aderholz, Shaun Roe, Z. Hajduk, Simonetta Gentile, A. Geiser, A. Soroko, M. Zdrazil, Q. Zhang, Yasushi Nagasaka, K-H. Noffz, K. Wyllie, Tara Shears, Vladimir Sulin, Edisher Tskhadadze, P. Roy, A.J. Flavell, D. Kouba, S. Dagan, P. B. Renton, K. Ryabchenko, E. Spiriti, K. Honscheid, G. Zuk, M. Simic, P. Gerlach, F. Molinie, Patrick Slattery, P. de Saintignon, Christoph Schwick, R. Spiwoks, J. Callahan, P. F. Klok, M. H. Shaevitz, A. H. Mahmood, I. Stumer, V. Klasen, G. De Zorzi, Paul Keener, M. Strauss, N. Zhang, Raymond Brock, F. Schaefer, Doug Gingrich, V. M. Kotov, K. Fuchs, K.H. Geib, R.L. English, Victor Kukhtin, S. Podkladkin, M. Valdata-Nappi, T. Hoare, U. Pfeiffer, H. Schick, Jie Chen, M. J. Kobel, Manuel Lozano, R. Marchesini, E. Pod, Christopher Bee, E.R.S. Candlin, Giovanna Ambrosini, K. W. Glitza, T. A. Hodges, O. Pukhov, Ph. Schune, William Trischuk, Christophe Clement, Yury Tikhonov, Rachid Mazini, V. Sosnovtzev, P. Perrodo, N.I. Bozko, Christoph Posch, D. Cacaut, R. de Asmundis, Reiner Hauser, I. Falleau, T. Buran, L. Bjorset, Y. Eisenberg, T. J. McMahon, M. J. Losty, J. Rothberg, R. Langstaff, Stavros Maltezos, W. Flegel, C. Geweniger, Irakli Minashvili, A. Staude, P. Breugnon, N. Dumont-Dayot, Dan Pantea, V. Cook, B. Kisielewski, Marjorie Shapiro, J.M. Yamartino, S. L. Wu, V. Konstantinov, Isabelle Wingerter-Seez, T. Kawamoto, P R Poffenberger, Gene E. Alexander, T. H. Burnett, H. Saidi, J. Treis, Wim Lavrijsen, D. J. Candlin, Guido Gagliardi, G. Midttun, K. Homma, A. 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Bashindjagian, Mario David, N. Felt, E. L. Barberio, R. Fedorchuk, W. Mohr, T. Schmid, V. Vuillemin, Didier Lacour, P. Grenier, D. La Marra, L. Mandelli, A.N. Larichev, T. K. Ohska, G. Mikenberg, C. Schumacher, M. J. Woudstra, S. Kiourkos, H. G. Moser, V.V. Sytnik, S. Vanini, Fred Wickens, Shawn McKee, J. Del Peso, P A. Delpierre, R.W. Dobinson, R. von Boehn-Bucholz, J. Sodomka, N. Sasao, F. Hartjes, R. Berthier, P.A. Cooke, H. Chakir, M. Merkin, J. Spelt, P. Stavina, V. Maximov, R.R. Mekhdiyev, M. Sessler, Jörgen Sjölin, P. Ponsot, E. Badescu, L. Vassilieva, J. Ulrichs, A. Pilling, D.V. Amelin, J. Wotschack, R. Nacasch, G. H. Trilling, D. Stephani, Richard C. Jared, Howard Gordon, F. Hogbe-Nlend, P. Pailler, Werner Riegler, R.A. Madsen, Jinan, I.G. Knowles, S. Sultansoy, Craig Blocker, D. Cauz, Ronald E. Miller, Gregor Herten, Miriam Lucio Martinez, P. Delebecque, A. Mirea, Chiara Meroni, M. P. J. Landon, Jose Flix, A. Joudon, Stefan Simion, Peter Kluit, J. E. Pilcher, Matteo Cavalli-Sforza, Alevtina Shmeleva, A. Klovning, Yona Oren, Daniel Fournier, Vladimir Cindro, H. Tischhauser, R. P. Thun, M. Moynot, Gibson, R. Wunstorf, Viktor Kramarenko, E. Gornicki, V. J. Guarino, J-Y. Hostachy, Helmuth Spieler, J. Bremer, J. Rabel, Paolo Bagnaia, A.M. Moiseev, Raimund Ströhmer, V. Simak, and A. T. Goshaw
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Physics ,Nuclear physics ,Particle physics ,Atlas (topology) ,Atlas detector ,Bibliography ,Drell–Yan process ,Technicolor ,Supersymmetry ,Particle detector ,Technical design - Published
- 1999
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24. RHO-RHO production by two photon scattering
- Author
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P. Schmüser, H. M. Fischer, J. Rimkus, V. Kadansky, D. Notz, H. U. Martyn, R. Rüsch, J. Pyrlik, H. L. Lynch, Gl Salmon, B. Löhr, P. Joos, B. Foster, A. Schultz von Dratzig, Walter Dr. Hillen, H. Hartmann, T. Meyer, John Freeman, M. Ogg, Georg Zobernig, G. Peise, H. Boerner, M. Wollstadt, K. W. Bell, R. Riethmüller, A. Ladage, Rj Cashmore, U. Karshon, H. Hultschig, W. G. Jones, J. Proudfoot, P. Koehler, S. Yarker, John Illingworth, P. Mättig, D. G. Cassel, W. Koch, B. H. Wiik, John Hart, P. L. Woodworth, N. A. Downie, R. Wedemeyer, Norbert Wermes, G. Poelz, Sau Lan Wu, T. R. Wyatt, H. G. Sander, B. Roe, H. Kowalski, D. R. Quarrie, U. Kötz, K. Lübelsmeyer, D. A. Garbutt, P. Söding, R.C.E. Devenish, P. Grossmann, D. M. Binnie, E. Hilger, D. Pandoulas, M. Holder, K. Gather, H. Burkhardt, P. Lecomte, R. Brandelik, D. Revel, Gy. Wolf, Y. Eisenberg, E.E. Ronat, W. Braunschweig, D. Lüke, G. Knop, G. Mikenberg, D. Heyland, D.W. Schmitz, P. J. Dornan, R. Fohrmann, P. Leu, Ehud Duchovni, D. H. Saxon, O. Römer, Stephen Lloyd, A. Shapira, D. Trines, W. Wallraff, Hermann Kolanoski, J. K. Sedgbeer, C. Youngman, L. Koepke, Roger Barlow, M. Schliwa, and I. C. Brock
- Subjects
Nuclear physics ,Physics ,Nuclear and High Energy Physics ,Two-photon excitation microscopy ,Scattering ,Electron–positron annihilation - Published
- 1980
- Full Text
- View/download PDF
25. The Failure of Parliamentary Government in France, 1840-1848
- Author
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Robert L. Koepke
- Subjects
Government ,Political science ,Parliamentary republic ,Parliamentary procedure ,Public administration - Published
- 1979
- Full Text
- View/download PDF
26. Direct Measurement of CharmedD+andD0Semileptonic Branching Ratios
- Author
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T. H. Burnett, Kevin Einsweiler, V. Cook, Norbert Wermes, J. Roehrig, W. H. Toki, P. M. Mockett, L. Koepke, J. Perrier, B. I. Eisenstein, A.C. Odian, B. Tripsas, R. Fabrizio, G. E. Gladding, A. L. Duncan, J. C. Sleeman, C. A. Heusch, R. M. Baltrusaitis, Jon J Thaler, M. Scarlatella, K. O. Bunnell, D. Wisinski, R. H. Schindler, J. J. Becker, R. E. Cassell, A. J.R. Weinstein, W. J. Wisniewski, L. Moss, G. P. Dubois, D. G. Hitlin, C. Del Papa, A. Seiden, D.E. Dorfan, F. Villa, J. J. Russell, Jay Hauser, A. L. Spadafora, H. F.W. Sadrozinski, T. Schalk, S. A. Plaetzer, D. Coffman, G. Blaylock, W. S. Lockman, S. Dado, F. Grancagnolo, D.H. Coward, R. P. Hamilton, R. F. Mozley, R. Partridge, A. Nappi, H. J. Willutzki, J. S. Brown, A. Wattenberg, and J. D. Richman
- Subjects
Semileptonic decay ,Physics ,Particle physics ,Materials science ,Meson ,Branching fraction ,Electron–positron annihilation ,Hadron ,Analytical chemistry ,General Physics and Astronomy ,Elementary particle ,Branching (polymer chemistry) ,Branching (linguistics) ,Nuclear physics ,Particle decay - Abstract
Measurements of the semileptonic branching ratios of charmed D/sup +/ and D/sup 0/ mesons are presented, from data collected at the psi(3770) in the Mark III detector at SPEAR. From a sample of events kinematically selected as charmed D/sup +/D/sup -/ or D/sup 0/D /sup 0/ pairs, the branching ratios R(D/sup +/..-->..e/sup +/+X) = (17.0 +- 1.9 +- 0.7)% and R(D/sup 0/..-->..e/sup +/+X) = (7.5 +- 1.1 +- 0.4 )% are obtained. The ratio of these measurements can be interpreted as the ratio of D/sup +/ and D/sup 0/ lifetimes tau/sup +//tau/sup 0/ = 2.3/sub -0.4-0.1/ /sub +0.5+0.1/ by neglect of the contribution of Cabibbo-suppressed decays to the total decay width.
- Published
- 1985
- Full Text
- View/download PDF
27. The Mark II detector for the SLC
- Author
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M. Kuhlen, F. Bulos, S. R. Klein, B. A. Barnett, C. Boswell, Z. Li, B. D. Milliken, M. Swartz, P. D. Dauncey, B. B. Brabson, A. Snyder, J. Dorfan, P. Voruganti, A. Petersen, Barry C. Barish, J. A. J. Matthews, R. Pitthan, R. Van Kooten, C. K. Jung, I. Juricic, M. Jaffre, G. H. Trilling, K. Braune, Mark E. Nelson, M. Chmeissani, R. Harr, G. S. Abrams, R. R. Larsen, A. M. Boyarski, R. P. Thun, Ryszard Stroynowski, F. Perrier, Jordan Nash, D. Fujino, A. Seiden, J Perl, J. Haggerty, Giorgio Gratta, Ballam J, F. Butler, B.A. Schumm, J. A. Jaros, J. G. Smith, Averill D, P. Rankin, L. Müller, S. Weisz, M. Yurko, J. W. Chapman, Adolphsen Ce, G. Lynch, S. O. Holmgren, A. Green, A. S. Schwarz, C. Zaccardelli, Hartmut Sadrozinski, Sherwood Parker, Clemens A. Heusch, M. L. Perl, C. von Zanthier, J. M. Brom, Walter R. Innes, J. Boyer, M. Hoenk, D. P. Stoker, King M, A. Weigend, K. Riles, Carl W. Akerlof, William T. Ford, Kenneth G. Hayes, Jacobsen Rg, Field Rc, Fordham C, W. Koska, A. J. Weir, Hinshaw Da, James P. Alexander, D. Hutchinson, C. Gatto, W. N. Murray, L. Labarga, F. A. Harris, D.P. Coupal, R. Tschirhart, Timothy Barklow, C.T. Munger, Stephen Robert Wagner, K. C. Moffeit, Alan Litke, Hearty C, M. Woods, J.F. Kral, D. L. Burke, Cords D, Michael Levi, L.A. Kowalski, Darien Wood, S. Vejcik, Drewer Dc, C.M. Hawkes, D.S. Koetke, R. Frey, J. A. McKenna, T. Glanzman, K. O'Shaughnessy, C. W. Peck, M. Alvarez, Hong Sj, D. Nitz, D. Y. Wu, S. Komamiya, Grosse-Wiesmann P, D. Blockus, J. Hylen, Harral B, E. Wicklund, A. J. Lankford, P.S. Drell, A. Koide, P. Weber, John E. Bartelt, Patricia R. Burchat, DeStaebler Hc, W. De Boer, G. Wormser, A. Breakstone, Frank C. Porter, W. B. Schmidke, S. L. White, E. Fernandez, Gero E, L. Koepke, M. Turala, G. J. Feldman, Robert E. Wright, K. K. Gan, D. Herrup, R. C. Wolf, D. E. Dorfan, H. O. Ogren, G. Bonvicini, Richard E. Taylor, George Gidal, F. Rouse, Fernandes D, A. R. Baden, Jeffrey Richman, A. J. Weinstein, M. Petradza, R. A. Ong, G. Hanson, F. Calviño, H. Veltman, W. Kozanecki, V. Luth, X. Gong, J.J. Gomez Cadenas, T. Himel, J. A. Kadyk, R. J. Cence, M. W. Schaad, E. Soderstrom, Thomas S. Mattison, D. Karlen, J. Kent, J. Fay, D. R. Rust, S. Watson, and Gerson Goldhaber
- Subjects
Physics ,Nuclear and High Energy Physics ,Luminosity (scattering theory) ,Physics::Instrumentation and Detectors ,Detector ,law.invention ,Nuclear physics ,Data acquisition ,Electromagnetic calorimeter ,law ,Electromagnetic coil ,Measuring instrument ,Physics::Accelerator Physics ,High Energy Physics::Experiment ,Collider ,Instrumentation ,Storage ring - Abstract
The Mark II detector has been upgraded in preparation for its role as the first detector to take data at the Stanford Linear Collider. The new detector components include the central drift chamber, the time-of-flight system, the coil, the endcap electromagnetic calorimeters and the beam energy and luminosity measuring devices. There have also been improvements in detector hermeticity. All of the major components were installed for a test run at the PEP storage ring (√s = 29 GeV) in 1985. This paper describes the upgraded detector, including its trigger and data acquisition systems, and gives performance figures for its components. Future improvements are also discussed.
- Published
- 1989
- Full Text
- View/download PDF
28. Evidence for a spin-1 gluon in three-jet events
- Author
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T. R. Wyatt, U. Kötz, John Freeman, M. Ogg, D. G. Cassel, B. Löhr, P. Joos, B. Foster, D. A. Garbutt, Walter Dr. Hillen, E. Wicklund, P. Mättig, G. Peise, Ehud Duchovni, H. Boerner, H. Hultschig, J. Pyrlik, Rj Cashmore, C. Youngman, D. Trines, T. Barklow, H. G. Sander, P. Lecomte, B. H. Wiik, John Hart, E. Hilger, Sau Lan Wu, D. R. Quarrie, S. Yarker, W. Wallraff, Hermann Kolanoski, J. K. Sedgbeer, H. M. Fischer, O. Römer, U. Karshon, M. Wollstadt, R. Brandelik, D. M. Binnie, J. Proudfoot, H. L. Lynch, M. A. Downie, V. Kadansky, A. Schultz von Dratzig, E.E. Ronat, P. Koehler, D. Notz, A. Shapira, L. Koepke, D. Pandoulas, Georg Zobernig, G. Knop, W. Koch, Norbert Wermes, H. Kowalski, I. C. Brock, K. Lübelsmeyer, R. A. Stern, P. Söding, M. Holder, R. Rüsch, K. Gather, Y. Eisenberg, G. Poelz, G. Rudolph, R. Riethmüller, K. W. Bell, W. Braunschweig, D. Lüke, D. H. Saxon, R.C.E. Devenish, Gy. Wolf, R. Wedemeyer, F. J. Kirschfink, G. Mikenberg, P. Schmüser, J. Rimkus, P. Grossmann, Stephen Lloyd, H. Hartmann, H. Burkhardt, B. Roe, W. G. Jones, I. Al-Agil, John Illingworth, P. Leu, P. L. Woodworth, Roger Barlow, M. Schliwa, D. Heyland, D.W. Schmitz, D. Revel, Gl Salmon, T. Meyer, P. J. Dornan, A. Ladage, R. Fohrmann, and H. U. Martyn
- Subjects
Physics ,Nuclear physics ,Nuclear and High Energy Physics ,Particle physics ,Electron–positron annihilation ,High Energy Physics::Phenomenology ,Hadron ,High Energy Physics::Experiment ,Kinematics ,Nuclear Experiment ,Confidence interval ,Standard deviation ,Gluon - Abstract
High-energy e+e--annihilation events obtained in the TASSO detector at PETRA have been used to determine the spin of the gluon in the reaction e+e- → qqg. We analysed angular correlations between the three jet axes. While vector gluons are consistent with the data (55% confidence limit), scalar gluons are disfavoured by 3.8 standard deviations, corresponding to a confidence level of about 10-4. Our conclusion is free of possible biases due to uncertainties in the fragmentation process or in determining the qqg kinematics from the observed hadrons. © 1980.
- Published
- 1980
- Full Text
- View/download PDF
29. COMPARISON OF E+E- ANNIHILATION WITH QCD AND DETERMINATION OF THE STRONG COUPLING-CONSTANT
- Author
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V. Kadansky, D. Trines, R. Rüsch, D. Lüke, H. L. Lynch, G. Mikenberg, A. Schultz von Dratzig, H. G. Sander, H. Kowalski, D. G. Cassel, W. G. Jones, M. Holder, K. Gather, J. Pyrlik, P. Grossmann, D. Heyland, W. Wallraff, H. Hartmann, O. Römer, D.W. Schmitz, M. Wollstadt, B. Roe, John Freeman, E.E. Ronat, Gl Salmon, Kw Bell, Gy. Wolf, Walter Dr. Hillen, John Illingworth, B. Foster, G. Peise, N. A. Downie, P. L. Woodworth, M. Ogg, Rj Cashmore, G. Knop, D. Revel, P. Schmüser, J. Sedgbeer, R. Fohrmann, H. Boerner, T. Meyer, J. Rimkus, H. M. Fischer, J. Proudfoot, S. Yarker, H. Hultschig, H. Burkhardt, A. Ladage, N Wermes, L. Koepke, B. H. Wiik, B. Löhr, R. Riethmüller, T. R. Wyatt, P. Joos, A. Shapira, I. C. Brock, Sau Lan Wu, P. J. Dornan, P. Koehler, R. Wedemeyer, G Zobernig, P. Leu, P. Mättig, D. Notz, D. R. Quarrie, Roger Barlow, M. Schliwa, D. H. Saxon, Y. Eisenberg, C. Youngman, U. Karshon, J. C. Hart, D. Pandoulas, Stephen Lloyd, D. M. Binnie, Hu Martyn, W. Braunschweig, P. Lecomte, R.C.E. Devenish, W. Koch, G. Poelz, K. Lübelsmeyer, P. Söding, U. Kötz, D. A. Garbutt, E. Hilger, and R. Brandelik
- Subjects
Coupling constant ,Quantum chromodynamics ,Quark ,Physics ,Nuclear and High Energy Physics ,Particle physics ,Annihilation ,Electron–positron annihilation ,High Energy Physics::Phenomenology ,Hadron ,Gluon ,Nuclear physics ,Fragmentation (mass spectrometry) ,High Energy Physics::Experiment ,Nuclear Experiment - Abstract
We have analyzed 1113 events of the reaction e+e− → hadrons at CM energies of 12 and 30 GeV in order to make a detailed comparison with QCD. Perturbative effects can be well separated from effects depending on the quark and gluon fragmentation parameters to yield a reliable measurement of the coupling constant αS. At 30 GeV, the result is αS = 0.17 ± 0.02 (statistical) ± 0.03 (systematic). QCD model predictions, using the fragmentation parameters determined along with αS, agree with both gross properties of the final states and with detailed features of the three-jet states.
- Published
- 1980
30. EVIDENCE FOR CHARGED PRIMARY PARTONS IN E+E--]2 JETS
- Author
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W. G. Jones, M. Holder, K. Gather, E.E. Ronat, P. Grossmann, G. Knop, D. Trines, D. G. Cassel, R. A. Stern, U. Kötz, H. L. Lynch, B. Foster, J. Sedgbeer, D. A. Garbutt, D. Lüke, E. Hilger, Walter Dr. Hillen, P. Mättig, W. Braunschweig, Hermann Kolanoski, H. G. Sander, G. Mikenberg, A. Schultz von Dratzig, D. Heyland, R. Wedemeyer, G. Peise, D.W. Schmitz, Gl Salmon, F. J. Kirschfink, P. Koehler, R. Brandelik, T. Barklow, T. Meyer, I. Al-Agil, D. R. Quarrie, T. R. Wyatt, H. Hultschig, V. Kadansky, John Freeman, R. Riethmüller, B. H. Wiik, H. M. Fischer, Ehud Duchovni, D. Notz, P. Lecomte, S. Yarker, L. Koepke, Sau Lan Wu, John Illingworth, P. J. Dornan, M. Ogg, D. Revel, Kw Bell, M. Wollstadt, R. Beuselink, R. Fohrmann, O. Römer, P. Schmüser, H. Kowalski, R.C.E. Devenish, P. L. Woodworth, A. Ladage, R. Rüsch, I. C. Brock, G Zobernig, N Wermes, J. Rimkus, Y. Eisenberg, P. Leu, G. Rudolph, P. Joos, C. Youngman, Hu Martyn, H. Boerner, K. Lübelsmeyer, P. Söding, E. Wicklund, Rj Cashmore, D. H. Saxon, H. Hartmann, D. Pandoulas, J. C. Hart, J. Proudfoot, Sl Lloyd, A. Shapira, W. Wallraff, W. Koch, G. Poelz, Gy. Wolf, H. Burkhardt, U. Karshon, D. M. Binnie, and J. Pyrlik
- Subjects
Nuclear physics ,Physics ,Nuclear and High Energy Physics ,Particle physics ,Primary (astronomy) ,Electron–positron annihilation ,Parton - Published
- 1981
31. K0-PRODUCTION IN E+E- ANNIHILATIONS AT 30 GEV CENTER OF MASS-ENERGY
- Author
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L. Koepke, H. Hultschig, Gl Salmon, B. H. Wiik, I. C. Brock, Sau Lan Wu, T. Meyer, J. Pyrlik, G Zobernig, W. Braunschweig, P. J. Dornan, M. Wollstadt, A. Ladage, P. Lecomte, Hu Martyn, P. Leu, Rj Cashmore, H. L. Lynch, U. Kötz, W. Koch, E.E. Ronat, G. Knop, A. Schultz von Dratzig, Kw Bell, B. Löhr, D. A. Garbutt, P. Schmüser, U. Karshon, O. Römer, G. Poelz, D. Trines, D. G. Cassel, R. Riethmüller, D. Lüke, H. Boerner, P. Joos, R.C.E. Devenish, D. Pandoulas, H. Kowalski, G. Mikenberg, B. Roe, K. Lübelsmeyer, P. Söding, P. Koehler, Gy. Wolf, R. Wedemeyer, E. Hilger, D. Heyland, P. Mättig, Y. Eisenberg, A. Shapira, D.W. Schmitz, C. Youngman, R. Brandelik, D. Notz, T. R. Wyatt, N Wermes, Roger Barlow, M. Schliwa, D. R. Quarrie, H. M. Fischer, D. H. Saxon, H. Burkhardt, N. A. Downie, J. Rimkus, R. Fohrmann, Walter Dr. Hillen, G. Peise, J. C. Hart, Sl Lloyd, S. Yarker, D. Revel, W. Wallraff, B. Foster, John Illingworth, P. L. Woodworth, D. M. Binnie, J. Sedgbeer, H. Hartmann, J. Proudfoot, V. Kadansky, H. G. Sander, John Freeman, M. Ogg, R. Rüsch, P. Grossmann, W. G. Jones, M. Holder, and K. Gather
- Subjects
Nuclear physics ,Physics ,Nuclear and High Energy Physics ,Particle physics ,Annihilation ,Production (computer science) ,Center of mass ,Scaling ,Energy (signal processing) - Abstract
Inclusive K0-production has been measured in e+e- annihilation at a center of mass energy of about W = 30 GeV. The ratio of K0 + K0 production to μ+μ- production is RK0 = 5.6 ± 1.1 (statist. error) ± 0.8 (system.error) This value is about a factor of three higher than RK0 at W = 7 GeV. The cross sections (s/β) dσ/dx is consistent with a scaling behaviour.
- Published
- 1980
32. TEST OF QED IN E+E- ANNIHILATION AT ENERGIES BETWEEN 12 AND 31.6 GEV
- Author
-
J. Pyrlik, D. H. Saxon, K. Lüberlsmeyer, Gl Salmon, U. Kötz, P. Koehler, H. Burkhardt, P. Grossmann, J. C. Hart, D. Notz, Kw Bell, Sl Lloyd, D. A. Garbutt, P. Schmüser, T. Meyer, P. Leu, W. Wallraff, H. Hartmann, H. Hultschig, O. Römer, B. H. Wiik, A. Ladage, H. L. Lynch, Sau Lan Wu, P. J. Dornan, W. Koch, D. Pandoulas, A. Schultz von Dratzig, M. Wollstadt, J. Proudfoot, B. Foster, G. Piese, D. Heyland, G. Poelz, A. Shapira, J. Sedgbeer, W. G. Jones, V. Kadansky, M. Holder, Rj Cashmore, K. Gather, D.W. Schmitz, R. Riethmüller, D. G. Cassel, H. Boerner, R.C.E. Devenish, R. Rüsch, Hu Martyn, P. Söding, Y. Eisenberg, C. Youngman, R. Wedemeyer, W. Braunschweig, E.E. Ronat, D. M. Binnie, Roger Barlow, M. Schliwa, E. Hilger, R. Fohrmann, U. Karshon, G. Knop, Gy. Wolf, L. Koepke, P. Lecomte, John Illingworth, T. R. Wyatt, R. Brandelik, I. C. Brock, G Zobernig, P. L. Woodworth, D. Lüke, G. Mikenberg, N. A. Downie, H. Kowalski, H. M. Fischer, J. Rimkus, P. Mättig, D. R. Quarrie, Walter Dr. Hillen, S. Yarker, N Wermes, B. Roe, D. Trines, D. Revel, John Freeman, M. Ogg, B. Löhr, H. G. Sander, and P. Joos
- Subjects
Physics ,Nuclear physics ,Nuclear and High Energy Physics ,Particle physics ,Annihilation ,Weinberg angle - Abstract
We have measured the reactions e+e− → e+e− → μ+μ− and e+e− → γγ at c.m. energies between 12 and 31.6 GeV. Excellent agreement with the predictions of QED has been found, resulting in cut off parameters Λ+ > 112 GeV and Λ− > 139 GeV for the first process and Λ+ > 34 GeV and Λ− > 42 GeV (95% c.1.) for the last one. A limit on the Weinberg angle of sin2θW < 0.55 (95% c.1.) has been obtained.
- Published
- 1980
33. Two photon results from TASSO
- Author
-
C. Youngman, R.C.E. Devenish, E.E. Ronat, Gl Salmon, H. L. Lynch, J. Rimkus, N. A. Downie, B. Roe, T. Meyer, H. U. Martyn, H. Hartmann, G. Knop, H. Fischer, R. Wedemeyer, Guenter Wolf, A. Ladage, M. Wollstadt, Norbert Wermes, D. Pandoulas, D. G. Cassel, Roger Barlow, B. Löhr, A. Shapira, M. Schliwa, H. Boerner, P. Joos, Georg Zobernig, T. R. Wyatt, M. Holder, P. Leu, R. Riethmüller, A. Schultz von Dratzig, B. Foster, H. Hultschig, P. Grossmann, U. Karshon, K. W. Bell, B. H. Wiik, John Hart, W. G. Jones, V. Kadansky, D. Revel, L. Koepke, Sau Lan Wu, J. Proudfoot, G. Mikenberg, I. C. Brock, K. Gather, John Illingworth, P. Mättig, D. Notz, J. Pyrlik, P. L. Woodworth, D. H. Saxon, D. Lüke, R. Rüsch, M. Ogg, W. Koch, D. M. Binnie, H. G. Sander, D. R. Quarrie, D. Heyland, G. Poelz, D.W. Schmitz, H. Kowalski, P. J. Dornan, Stephen Lloyd, R. Fohrmann, D. Trines, P. Schmüser, R. J. Cashmore, W. Wallraff, U. Kötz, Hermann Kolanoski, J. K. Sedgbeer, D. A. Garbutt, E. Hilger, P. Koehler, R. Brandelik, K. Lübelsmeyer, P. Söding, Walter Dr. Hillen, G. Peise, P. Lecomte, J. Freemann, S. Yarker, Y. Eisenberg, W. Braunschweig, and O. Römer
- Subjects
Physics ,Nuclear physics ,Annihilation ,Two-photon excitation microscopy ,Physics::Plasma Physics ,Detector ,Computer Science::Computation and Language (Computational Linguistics and Natural Language and Speech Processing) ,High Energy Physics::Experiment ,Invariant mass ,Physics::History of Physics ,Storage ring - Abstract
Two photon annihilation processes were observed with the TASSO detector at the e+e- storage ring PETRA. We report on the analyses of untagged and single tag events.
- Published
- 1980
- Full Text
- View/download PDF
34. CHARGED PION, KAON, PROTON AND ANTIPROTON PRODUCTION IN HIGH-ENERGY E+E- ANNIHILATIONS
- Author
-
R.C.E. Devenish, Walter Dr. Hillen, G. Peise, Gl Salmon, B. Roe, Rj Cashmore, H. M. Fischer, John Freeman, Gy. Wolf, W. Braunschweig, E. Hilger, S. Yarker, M. Ogg, D. Heyland, N. A. Downie, T. Meyer, D.W. Schmitz, A. Ladage, P. Lecomte, P. Grossmann, W. Wallraff, J. Pyrlik, H. Burkhardt, W. G. Jones, M. Holder, K. Gather, H. Hartmann, H. L. Lynch, D. Pandoulas, Roger Barlow, M. Schliwa, A. Schultz von Dratzig, E.E. Ronat, R. Brandelik, R. Wedemeyer, J. Proudfoot, Y. Eisenberg, G. Knop, D. Revel, C. Youngman, D. G. Cassel, Hu Martyn, K. Lübelsmeyer, L. Koepke, A. Shapira, H. Kowalski, B. Foster, P. Söding, J. Sedgbeer, I. C. Brock, G Zobernig, U. Karshon, W. Koch, U. Kötz, P. Koehler, D. A. Garbutt, G. Poelz, P. Mättig, D. Notz, H. G. Sander, V. Kadansky, O. Römer, Kw Bell, D. R. Quarrie, R. Fohrmann, D. Lüke, G. Mikenberg, D. Trines, R. Rüsch, P. Schmüser, R. Riethmüller, B. Löhr, P. Leu, P. Joos, H. Hultschig, Hermann Kolanoski, B. H. Wiik, H. Boerner, Sau Lan Wu, P. J. Dornan, N Wermes, D. H. Saxon, J. C. Hart, Sl Lloyd, D. M. Binnie, John Illingworth, T. R. Wyatt, P. L. Woodworth, M. Wollstadt, and J. Rimkus
- Subjects
Physics ,Nuclear and High Energy Physics ,Particle physics ,Proton ,Nuclear Theory ,Hadron ,Nuclear physics ,Baryon ,Momentum ,Time of flight ,Pion ,Antiproton ,Yield (chemistry) ,High Energy Physics::Experiment ,Nuclear Experiment - Abstract
Production of pions, kaons, protons and antiprotons has been studied in e + e − annihilations at 12 and 30 GeV centre of mass energy using time of flight techniques. The fractional yield of charged kaons and baryons appears to rise with outgoing particle momentum. At our highest energy at least 40% of e + e − annihilations into hadrons are estimated to contain baryons.
- Published
- 1980
35. Federal Legislation, Clean Air, and Local Industry
- Author
-
Robert L. Koepke and Charles A. Thornton
- Subjects
business.industry ,Geography, Planning and Development ,Legislation ,Public relations ,Public administration ,business ,Local industry ,Earth-Surface Processes - Published
- 1981
- Full Text
- View/download PDF
36. Search for the Higgs boson in the H→WW→ℓνjj decay channel at s=7 TeV with the ATLAS detector
- Author
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Aad, G., Abajyan, T., Abbott, B., Abdallah, J., Abdel Khalek, S., Abdelalim, A. A., Abdinov, O., Aben, R., Abi, B., Abolins, M., Abouzeid, O. S., Abramowicz, H., Abreu, H., Acerbi, E., Acharya, B. S., Adamczyk, L., Adams, D. L., Addy, T. N., Adelman, J., Adomeit, S., Adragna, P., Adye, T., Aefsky, S., Aguilar Saavedra, J. A., Agustoni, M., Aharrouche, M., Ahlen, S. P., Ahles, F., Ahmad, A., Ahsan, M., Aielli, G., Akdogan, T., A°kesson, T. P. A., Akimoto, G., Akimov, A. V., Alam, M. S., Alam, M. A., Albert, J., Albrand, S., Aleksa, M., Aleksandrov, I. N., Alessandria, F., Alexa, C., Alexander, G., Alexandre, G., Alexopoulos, T., Alhroob, M., Aliev, M., Alimonti, G., Alison, J., Allbrooke, B. M. M., Allport, P. P., Allwood Spiers, S. E., Almond, J., Aloisio, A., Alon, R., Alonso, A., Alonso, F., Alvarez Gonzalez, B., Alviggi, M. G., Amako, K., Amelung, C., Ammosov, V. V., Amorim, A., Amram, N., Anastopoulos, C., Ancu, L. S., Andari, N., Andeen, T., Anders, C. F., Anders, G., Anderson, K. J., Andreazza, A., Andrei, V., Anduaga, X. S., Anger, P., Angerami, A., Anghinolfi, F., Anisenkov, A., Anjos, N., Annovi, A., Antonaki, A., Antonelli, M., Antonov, A., Antos, J., Anulli, F., Aoki, M., Aoun, S., Aperio Bella, L., Apolle, R., Arabidze, G., Aracena, I., Arai, Y., Arce, A. T. H., Arfaoui, S., Arguin, J. F., Arik, E., Arik, M., Armbruster, A. J., Arnaez, O., Arnal, V., Arnault, C., Artamonov, A., Artoni, G., Arutinov, D., Asai, S., Asfandiyarov, R., Ask, S., A°sman, B., Asquith, L., Assamagan, K., Astbury, A., Aubert, B., Auge, E., Augsten, K., Aurousseau, M., Avolio, G., Avramidou, R., Axen, D., Azuelos, G., Azuma, Y., Baak, M. A., Baccaglioni, G., Bacci, C., Bach, A. M., Bachacou, H., Bachas, K., Backes, M., Backhaus, M., Badescu, E., Bagnaia, P., Bahinipati, S., Bai, Y., Bailey, D. C., Bain, T., Baines, J. T., Baker, O. K., Baker, M. D., Baker, S., Banas, E., Banerjee, P., Banerjee, S. w., Banfi, D., Bangert, A., Bansal, V., Bansil, H. S., Barak, L., Baranov, S. P., Barbaro Galtieri, A., Barber, T., Barberio, E. L., Barberis, Dario, Barbero, M., Bardin, D. Y., Barillari, T., Barisonzi, M., Barklow, T., Barlow, N., Barnett, B. M., Barnett, R. M., Baroncelli, A., Barone, G., Barr, A. J., Barreiro, F., Barreiro Guimara~es da Costa, J., Barrillon, P., Bartoldus, R., Barton, A. E., Bartsch, V., Bates, R. L., Batkova, L., Batley, J. R., Battaglia, A., Battistin, M., Bauer, F., Bawa, H. S., Beale, S., Beau, T., Beauchemin, P. H., Beccherle, R., Bechtle, P., Beck, H. P., Becker, A. K., Becker, S., Beckingham, M., Becks, K. H., Beddall, A. J., Beddall, A., Bedikian, S., Bednyakov, V. A., Bee, C. P., Beemster, L. J., Begel, M., Behar Harpaz, S., Beimforde, M., Belanger Champagne, C., Bell, P. J., Bell, W. H., Bella, G., Bellagamba, L., Bellina, F., Bellomo, M., Belloni, A., Beloborodova, O., Belotskiy, K., Beltramello, O., Benary, O., Benchekroun, D., Bendtz, K., Benekos, N., Benhammou, Y., Benhar Noccioli, E., Benitez Garcia, J. A., Benjamin, D. P., Benoit, M., Bensinger, J. R., Benslama, K., Bentvelsen, S., Berge, D., Bergeaas Kuutmann, E., Berger, N., Berghaus, F., Berglund, E., Beringer, J., Bernat, P., Bernhard, R., Bernius, C., Berry, T., Bertella, C., Bertin, A., Bertolucci, F., Besana, M. I., Besjes, G. J., Besson, N., Bethke, S., Bhimji, W., Bianchi, R. M., Bianco, M., Biebel, O., Bieniek, S. P., Bierwagen, K., Biesiada, J., Biglietti, M., Bilokon, H., Bindi, M., Binet, S., Bingul, A., Bini, C., Biscarat, C., Bitenc, U., Black, K. M., Blair, R. E., Blanchard, J. B., Blanchot, G., Blazek, T., Blocker, C., Blocki, J., Blondel, A., Blum, W., Blumenschein, U., Bobbink, G. J., Bobrovnikov, V. B., Bocchetta, S. S., Bocci, A., Boddy, C. R., Boehler, M., Boek, J., Boelaert, N., Bogaerts, J. A., Bogdanchikov, A., Bogouch, A., Bohm, C., Bohm, J., Boisvert, V., Bold, T., Boldea, V., Bolnet, N. M., Bomben, M., Bona, M., Boonekamp, M., Booth, C. N., Bordoni, S., Borer, C., Borisov, A., Borissov, G., Borjanovic, I., Borri, M., Borroni, S., Bortolotto, V., Bos, K., Boscherini, D., Bosman, M., Boterenbrood, H., Bouchami, J., Boudreau, J., Bouhova Thacker, E. V., Boumediene, D., Bourdarios, C., Bousson, N., Boveia, A., Boyd, J., Boyko, I. R., Bozovic Jelisavcic, I., Bracinik, J., Branchini, P., Brandt, A., Brandt, G., Brandt, O., Bratzler, U., Brau, B., Brau, J. E., Braun, H. M., Brazzale, S. F., Brelier, B., Bremer, J., Brendlinger, K., Brenner, R., Bressler, S., Britton, D., Brochu, F. M., Brock, I., Brock, R., Broggi, F., Bromberg, C., Bronner, J., Brooijmans, G., Brooks, T., Brooks, W. K., Brown, G., Brown, H., Bruckman de Renstrom, P. A., Bruncko, D., Bruneliere, R., Brunet, S., Bruni, A., Bruni, G., Bruschi, M., Buanes, T., Buat, Q., Bucci, F., Buchanan, J., Buchholz, P., Buckingham, R. M., Buckley, A. G., Buda, S. I., Budagov, I. A., Budick, B., Bu¨scher, V., Bugge, L., Bulekov, O., Bundock, A. C., Bunse, M., Buran, T., Burckhart, H., Burdin, S., Burgess, T., Burke, S., Busato, E., Bussey, P., Buszello, C. P., Butler, B., Butler, J. M., Buttar, C. M., Butterworth, J. M., Buttinger, W., Cabrera Urba´n, S., Caforio, D., Cakir, O., Calafiura, P., Calderini, G., Calfayan, P., Calkins, R., Caloba, L. P., Caloi, R., Calvet, D., Calvet, S., Camacho Toro, R., Camarri, P., Cameron, D., Caminada, L. M., Campana, S., Campanelli, M., Canale, V., Canelli, F., Canepa, A., Cantero, J., Cantrill, R., Capasso, L., Capeans Garrido, M. D. M., Caprini, I., Caprini, M., Capriotti, D., Capua, M., Caputo, R., Cardarelli, R., Carli, T., Carlino, G., Carminati, L., Caron, B., Caron, S., Carquin, E., Carrillo Montoya, G. D., Carter, A. A., Carter, J. R., Carvalho, J., Casadei, D., Casado, M. P., Cascella, M., Caso, C., Castaneda Hernandez, A. M., Castaneda Miranda, E., Castillo Gimenez, V., Castro, N. F., Cataldi, G., Catastini, P., Catinaccio, A., Catmore, J. R., Cattai, A., Cattani, G., Caughron, S., Cavalleri, P., Cavalli, D., Cavalli Sforza, M., Cavasinni, V., Ceradini, F., Cerqueira, A. S., Cerri, A., Cerrito, L., Cerutti, F., Cetin, S. A., Chafaq, A., Chakraborty, D., Chalupkova, I., Chan, K., Chapleau, B., Chapman, J. D., Chapman, J. W., Chareyre, E., Charlton, D. G., Chavda, V., Chavez Barajas, C. A., Cheatham, S., Chekanov, S., Chekulaev, S. V., Chelkov, G. A., Chelstowska, M. A., Chen, C., Chen, H., Chen, S., Chen, X., Chen, Y., Cheplakov, A., Cherkaoui El Moursli, R., Chernyatin, V., Cheu, E., Cheung, S. L., Chevalier, L., Chiefari, G., Chikovani, L., Childers, J. T., Chilingarov, A., Chiodini, G., Chisholm, A. S., Chislett, R. T., Chitan, A., Chizhov, M. V., Choudalakis, G., Chouridou, S., Christidi, I. A., Christov, A., Chromek Burckhart, D., Chu, M. L., Chudoba, J., Ciapetti, G., Ciftci, A. K., Ciftci, R., Cinca, D., Cindro, V., Ciocca, C., Ciocio, A., Cirilli, M., Cirkovic, P., Citterio, M., Ciubancan, M., Clark, A., Clark, P. J., Clarke, R. N., Cleland, W., Clemens, J. C., Clement, B., Clement, C., Coadou, Y., Cobal, M., Coccaro, Andrea, Cochran, J., Cogan, J. G., Coggeshall, J., Cogneras, E., Colas, J., Cole, S., Colijn, A. P., Collins, N. J., Collins Tooth, C., Collot, J., Colombo, T., Colon, G., Conde Muin~o, P., Coniavitis, E., Conidi, M. C., Consonni, S. M., Consorti, V., Constantinescu, S., Conta, C., Conti, G., Conventi, F., Cooke, M., Cooper, B. D., Cooper Sarkar, A. M., Copic, K., Cornelissen, T., Corradi, M., Corriveau, F., Cortes Gonzalez, A., Cortiana, G., Costa, G., Costa, M. J., Costanzo, D., Costin, T., Co^te´, D., Courneyea, L., Cowan, G., Cowden, C., Cox, B. E., Cranmer, K., Crescioli, F., Cristinziani, M., Crosetti, G., Cre´pe´ Renaudin, S., Cuciuc, C. M., Cuenca Almenar, C., Cuhadar Donszelmann, T., Curatolo, M., Curtis, C. J., Cuthbert, C., Cwetanski, P., Czirr, H., Czodrowski, P., Czyczula, Z., D'Auria, S., D'Onofrio, M., D'Orazio, A., Da Cunha Sargedas De Sousa, M. J., Da Via, C., Dabrowski, W., Dafinca, A., Dai, T., Dallapiccola, C., Dam, M., Dameri, M., Damiani, D. S., Danielsson, H. O., Dao, V., Darbo, G., Darlea, G. L., Dassoulas, J. A., Davey, W., Davidek, T., Davidson, N., Davidson, R., Davies, E., Davies, M., Davignon, O., Davison, A. R., Davygora, Y., Dawe, E., Dawson, I., Daya Ishmukhametova, R. K., De, K., de Asmundis, R., De Castro, S., De Cecco, S., de Graat, J., De Groot, N., de Jong, P., De La Taille, C., De la Torre, H., De Lorenzi, F., de Mora, L., De Nooij, L., De Pedis, D., De Salvo, A., De Sanctis, U., De Santo, A., De Vivie De Regie, J. B., De Zorzi, G., Dearnaley, W. J., Debbe, R., Debenedetti, C., Dechenaux, B., Dedovich, D. V., Degenhardt, J., Del Papa, C., Del Peso, J., Del Prete, T., Delemontex, T., Deliyergiyev, M., Dell'Acqua, A., Dell'Asta, L., Della Pietra, M., della Volpe, D., Delmastro, M., Delsart, P. A., Deluca, C., Demers, S., Demichev, M., Demirkoz, B., Deng, J., Denisov, S. P., Derendarz, D., Derkaoui, J. E., Derue, F., Dervan, P., Desch, K., Devetak, E., Deviveiros, P. O., Dewhurst, A., Dewilde, B., Dhaliwal, S., Dhullipudi, R., Di Ciaccio, A., Di Ciaccio, L., Di Girolamo, A., Di Girolamo, B., Di Luise, S., Di Mattia, A., Di Micco, B., Di Nardo, R., Di Simone, A., Di Sipio, R., Diaz, M. A., Diehl, E. B., Dietrich, J., Dietzsch, T. A., Diglio, S., Dindar Yagci, K., Dingfelder, J., Dinut, F., Dionisi, C., Dita, P., Dita, S., Dittus, F., Djama, F., Djobava, T., do Vale, M. A. B., Do Valle Wemans, A., Doan, T. K. O., Dobbs, M., Dobinson, R., Dobos, D., Dobson, E., Dodd, J., Doglioni, C., Doherty, T., Doi, Y., Dolejsi, J., Dolenc, I., Dolezal, Z., Dolgoshein, B. A., Dohmae, T., Donadelli, M., Donini, J., Dopke, J., Doria, A., Dos Anjos, A., Dotti, A., Dova, M. T., Doxiadis, A. D., Doyle, A. T., Dris, M., Dubbert, J., Dube, S., Duchovni, E., Duckeck, G., Dudarev, A., Dudziak, F., Du¨hrssen, M., Duerdoth, I. P., Duflot, L., Dufour, M. A., Duguid, L., Dunford, M., Duran Yildiz, H., Duxfield, R., Dwuznik, M., Dydak, F., Du¨ren, M., Ebke, J., Eckweiler, S., Edmonds, K., Edson, W., Edwards, C. A., Edwards, N. C., Ehrenfeld, W., Eifert, T., Eigen, G., Einsweiler, K., Eisenhandler, E., Ekelof, T., El Kacimi, M., Ellert, M., Elles, S., Ellinghaus, F., Ellis, K., Ellis, N., Elmsheuser, J., Elsing, M., Emeliyanov, D., Engelmann, R., Engl, A., Epp, B., Erdmann, J., Ereditato, A., Eriksson, D., Ernst, J., Ernst, M., Ernwein, J., Errede, D., Errede, S., Ertel, E., Escalier, M., Esch, H., Escobar, C., Espinal Curull, X., Esposito, B., Etienne, F., Etienvre, A. I., Etzion, E., Evangelakou, D., Evans, H., Fabbri, L., Fabre, C., Fakhrutdinov, R. M., Falciano, S., Fang, Y., Fanti, M., Farbin, A., Farilla, A., Farley, J., Farooque, T., Farrell, S., Farrington, S. M., Farthouat, P., Fassnacht, P., Fassouliotis, D., Fatholahzadeh, B., Favareto, Andrea, Fayard, L., Fazio, S., Febbraro, R., Federic, P., Fedin, O. L., Fedorko, W., Fehling Kaschek, M., Feligioni, L., Fellmann, D., Feng, C., Feng, E. J., Fenyuk, A. B., Ferencei, J., Fernando, W., Ferrag, S., Ferrando, J., Ferrara, V., Ferrari, A., Ferrari, P., Ferrari, R., Ferreira de Lima, D. E., Ferrer, A., Ferrere, D., Ferretti, C., Ferretto Parodi, A., Fiascaris, M., Fiedler, F., Filipc?ic?, A., Filthaut, F., Fincke Keeler, M., Fiolhais, M. C. N., Fiorini, L., Firan, A., Fischer, G., Fisher, M. J., Flechl, M., Fleck, I., Fleckner, J., Fleischmann, P., Fleischmann, S., Flick, T., Floderus, A., Flores Castillo, L. R., Flowerdew, M. J., Fonseca Martin, T., Formica, A., Forti, A., Fortin, D., Fournier, D., Fox, H., Francavilla, P., Franchini, M., Franchino, S., Francis, D., Frank, T., Franz, S., Fraternali, M., Fratina, S., French, S. T., Friedrich, C., Friedrich, F., Froeschl, R., Froidevaux, D., Frost, J. A., Fukunaga, C., Fullana Torregrosa, E., Fulsom, B. G., Fuster, J., Gabaldon, C., Gabizon, O., Gadfort, T., Gadomski, S., Gagliardi, Guido, Gagnon, P., Galea, C., Gallas, E. J., Gallo, V., Gallop, B. J., Gallus, P., Gan, K. K., Gao, Y. S., Gaponenko, A., Garberson, F., Garcia Sciveres, M., Garci´a, C., Garci´a Navarro, J. E., Gardner, R. W., Garelli, N., Garitaonandia, H., Garonne, V., Garvey, J., Gatti, C., Gaudio, G., Gaur, B., Gauthier, L., Gauzzi, P., Gavrilenko, I. L., Gay, C., Gaycken, G., Gazis, E. N., Ge, P., Gecse, Z., Gee, C. N. P., Geerts, D. A. A., Geich Gimbel, C. h., Gellerstedt, K., Gemme, C., Gemmell, A., Genest, M. H., Gentile, S., George, M., George, S., Gerlach, P., Gershon, A., Geweniger, C., Ghazlane, H., Ghodbane, N., Giacobbe, B., Giagu, S., Giakoumopoulou, V., Giangiobbe, V., Gianotti, F., Gibbard, B., Gibson, A., Gibson, S. M., Gillberg, D., Gillman, A. R., Gingrich, D. M., Ginzburg, J., Giokaris, N., Giordani, M. P., Giordano, R., Giorgi, F. M., Giovannini, P., Giraud, P. F., Giugni, D., Giunta, M., Giusti, P., Gjelsten, B. K., Gladilin, L. K., Glasman, C., Glatzer, J., Glazov, A., Glitza, K. W., Glonti, G. L., Goddard, J. R., Godfrey, J., Godlewski, J., Goebel, M., Go¨pfert, T., Goeringer, C., Go¨ssling, C., Goldfarb, S., Golling, T., Gomes, A., Gomez Fajardo, L. S., Gonc¸alo, R., Goncalves Pinto Firmino Da Costa, J., Gonella, L., Gonzalez, S., Gonza´lez de la Hoz, S., Gonzalez Parra, G., Gonzalez Silva, M. L., Gonzalez Sevilla, S., Goodson, J. J., Goossens, L., Gorbounov, P. A., Gordon, H. A., Gorelov, I., Gorfine, G., Gorini, B., Gorini, E., Goris?ek, A., Gornicki, E., Gosdzik, B., Goshaw, A. T., Gosselink, M., Gostkin, M. I., Gough Eschrich, I., Gouighri, M., Goujdami, D., Goulette, M. P., Goussiou, A. G., Goy, C., Gozpinar, S., Grabowska Bold, I., Grafstro¨m, P., Grahn, K. J., Grancagnolo, F., Grancagnolo, S., Grassi, V., Gratchev, V., Grau, N., Gray, H. M., Gray, J. A., Graziani, E., Grebenyuk, O. G., Greenshaw, T., Greenwood, Z. D., Gregersen, K., Gregor, I. M., Grenier, P., Griffiths, J., Grigalashvili, N., Grillo, A. A., Grinstein, S., Grishkevich, Y. V., Grivaz, J. F., Gross, E., Grosse Knetter, J., Groth Jensen, J., Grybel, K., Guest, D., Guicheney, C., Guindon, S., Gul, U., Guler, H., Gunther, J., Guo, B., Guo, J., Gutierrez, P., Guttman, N., Gutzwiller, O., Guyot, C., Gwenlan, C., Gwilliam, C. B., Haas, A., Haas, S., Haber, C., Hadavand, H. K., Hadley, D. R., Haefner, P., Hahn, F., Haider, S., Hajduk, Z., Hakobyan, H., Hall, D., Haller, J., Hamacher, K., Hamal, P., Hamer, M., Hamilton, A., Hamilton, S., Han, L., Hanagaki, K., Hanawa, K., Hance, M., Handel, C., Hanke, P., Hansen, J. R., Hansen, J. B., Hansen, J. D., Hansen, P. H., Hansson, P., Hara, K., Hare, G. A., Harenberg, T., Harkusha, S., Harper, D., Harrington, R. D., Harris, O. M., Hartert, J., Hartjes, F., Haruyama, T., Harvey, A., Hasegawa, S., Hasegawa, Y., Hassani, S., Haug, S., Hauschild, M., Hauser, R., Havranek, M., Hawkes, C. M., Hawkings, R. J., Hawkins, A. D., Hawkins, D., Hayakawa, T., Hayashi, T., Hayden, D., Hays, C. P., Hayward, H. S., Haywood, S. J., He, M., Head, S. J., Hedberg, V., Heelan, L., Heim, S., Heinemann, B., Heisterkamp, S., Helary, L., Heller, C., Heller, M., Hellman, S., Hellmich, D., Helsens, C., Henderson, R. C. W., Henke, M., Henrichs, A., Henriques Correia, A. M., Henrot Versille, S., Hensel, C., Henß, T., Hernandez, C. M., Herna´ndez Jime´nez, Y., Herrberg, R., Herten, G., Hertenberger, R., Hervas, L., Hesketh, G. G., Hessey, N. P., Higo´n Rodriguez, E., Hill, J. C., Hiller, K. H., Hillert, S., Hillier, S. J., Hinchliffe, I., Hines, E., Hirose, M., Hirsch, F., Hirschbuehl, D., Hobbs, J., Hod, N., Hodgkinson, M. C., Hodgson, P., Hoecker, A., Hoeferkamp, M. R., Hoffman, J., Hoffmann, D., Hohlfeld, M., Holder, M., Holmgren, S. O., Holy, T., Holzbauer, J. L., Hong, T. M., Hooft van Huysduynen, L., Horn, C., Horner, S., Hostachy, J. Y., Hou, S., Hoummada, A., Howard, J., Howarth, J., Hristova, I., Hrivnac, J., Hryn'Ova, T., Hsu, P. J., Hsu, S. C., Hubacek, Z., Hubaut, F., Huegging, F., Huettmann, A., Huffman, T. B., Hughes, E. W., Hughes, G., Huhtinen, M., Hurwitz, M., Husemann, U., Huseynov, N., Huston, J., Huth, J., Iacobucci, G., Iakovidis, G., Ibbotson, M., Ibragimov, I., Iconomidou Fayard, L., Idarraga, J., Iengo, P., Igonkina, O., Ikegami, Y., Ikeno, M., Iliadis, D., Ilic, N., Ince, T., Inigo Golfin, J., Ioannou, P., Iodice, M., Iordanidou, K., Ippolito, V., Irles Quiles, A., Isaksson, C., Ishino, M., Ishitsuka, M., Ishmukhametov, R., Issever, C., Istin, S., Ivashin, A. V., Iwanski, W., Iwasaki, H., Izen, J. M., Izzo, V., Jackson, B., Jackson, J. N., Jackson, P., Jaekel, M. R., Jain, V., Jakobs, K., Jakobsen, S., Jakoubek, T., Jakubek, J., Jana, D. K., Jansen, E., Jansen, H., Jantsch, A., Janus, M., Jarlskog, G., Jeanty, L., Jen La Plante, I., Jennens, D., Jenni, P., Jez?, P., Je´ze´quel, S., Jha, M. K., Ji, H., Ji, W., Jia, J., Jiang, Y., Jimenez Belenguer, M., Jin, S., Jinnouchi, O., Joergensen, M. D., Joffe, D., Johansen, M., Johansson, K. E., Johansson, P., Johnert, S., Johns, K. A., Jon And, K., Jones, G., Jones, R. W. L., Jones, T. J., Joram, C., Jorge, P. M., Joshi, K. D., Jovicevic, J., Jovin, T., Ju, X., Jung, C. A., Jungst, R. M., Juranek, V., Jussel, P., Juste Rozas, A., Kabana, S., Kaci, M., Kaczmarska, A., Kadlecik, P., Kado, M., Kagan, H., Kagan, M., Kajomovitz, E., Kalinin, S., Kalinovskaya, L. V., Kama, S., Kanaya, N., Kaneda, M., Kaneti, S., Kanno, T., Kantserov, V. A., Kanzaki, J., Kaplan, B., Kapliy, A., Kaplon, J., Kar, D., Karagounis, M., Karakostas, K., Karnevskiy, M., Kartvelishvili, V., Karyukhin, A. N., Kashif, L., Kasieczka, G., Kass, R. D., Kastanas, A., Kataoka, M., Kataoka, Y., Katsoufis, E., Katzy, J., Kaushik, V., Kawagoe, K., Kawamoto, T., Kawamura, G., Kayl, M. S., Kazanin, V. A., Kazarinov, M. Y., Keeler, R., Kehoe, R., Keil, M., Kekelidze, G. D., Keller, J. S., Kenyon, M., Kepka, O., Kerschen, N., Kers?evan, B. P., Kersten, S., Kessoku, K., Keung, J., Khalil zada, F., Khandanyan, H., Khanov, A., Kharchenko, D., Khodinov, A., Khomich, A., Khoo, T. J., Khoriauli, G., Khoroshilov, A., Khovanskiy, V., Khramov, E., Khubua, J., Kim, H., Kim, S. H., Kimura, N., Kind, O., King, B. T., King, M., King, R. S. B., Kirk, J., Kiryunin, A. E., Kishimoto, T., Kisielewska, D., Kitamura, T., Kittelmann, T., Kladiva, E., Klein, M., Klein, U., Kleinknecht, K., Klemetti, M., Klier, A., Klimek, P., Klimentov, A., Klingenberg, R., Klinger, J. A., Klinkby, E. B., Klioutchnikova, T., Klok, P. F., Klous, S., Kluge, E. E., Kluge, T., Kluit, P., Kluth, S., Knecht, N. S., Kneringer, E., Knoops, E. B. F. G., Knue, A., B. R., Ko, Kobayashi, T., Kobel, M., Kocian, M., Kodys, P., Ko¨neke, K., Ko¨nig, A. C., Koenig, S., Ko¨pke, L., Koetsveld, F., Koevesarki, P., Koffas, T., Koffeman, E., Kogan, L. A., Kohlmann, S., Kohn, F., Kohout, Z., Kohriki, T., Koi, T., Kolachev, G. 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Zitoun, L. Zivkovic, V. V. Zmouchko, G. Zobernig, A. Zoccoli, M. z. Nedden, V. Zutshi, and L. Zwalinski
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Nuclear and High Energy Physics ,HIGGS BOSON ,W BOSON ,HADRON-HADRON COLLISIONS ,High Energy Physics::Phenomenology ,High Energy Physics::Experiment ,LHC ,ATLAS ,WW ,Higgs - Abstract
A search for the Standard Model Higgs boson has been performed in the H->WW->lnujj channel using 4.7 fb^-1 of pp collision data recorded at a centre-of-mass energy of sqrt(s) = 7 TeV with the ATLAS detector at the Large Hadron Collider. Higgs boson candidates produced in association with zero, one or two jets are included in the analysis to maximize the acceptance for both gluon fusion and weak boson fusion Higgs boson production processes. No significant excess of events is observed over the expected background and limits on the Higgs boson production cross section are derived for a Higgs boson mass in the range 300 GeV < mH < 600 GeV. The best sensitivity is reached for mH = 400 GeV, where the observed (expected) 95% confidence level upper bound on the cross section for H->WW produced in association with zero or one jet is 2.2 pb (1.9 pb), corresponding to 1.9 (1.6) times the Standard Model prediction. In the Higgs boson plus two jets channel, which is more sensitive to the weak boson fusion process, the observed (expected) 95% confidence level upper bound on the cross section for H->WW production with mH = 400 GeV is 0.7 pb (0.6 pb), corresponding to 7.9 (6.5) times the Standard Model prediction.
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37. CSNK2 suppresses autophagy by activating FLN-NHL-containing TRIM proteins.
- Author
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Hoenigsperger H, Koepke L, Acharya D, Hunszinger V, Freisem D, Grenzner A, Wiese S, Kirchhoff F, Gack MU, and Sparrer KMJ
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- Humans, Phosphorylation, HEK293 Cells, Beclin-1 metabolism, Intracellular Signaling Peptides and Proteins metabolism, Autophagosomes metabolism, HeLa Cells, Ubiquitin-Protein Ligases metabolism, Carrier Proteins, Autophagy physiology, Casein Kinase II metabolism, Tripartite Motif Proteins metabolism, Autophagy-Related Protein-1 Homolog metabolism
- Abstract
Macroautophagy/autophagy is a tightly regulated cellular process integral to homeostasis and innate immunity. As such, dysregulation of autophagy is associated with cancer, neurodegenerative disorders, and infectious diseases. While numerous factors that promote autophagy have been characterized, the key mechanisms that prevent excessive autophagy are less well understood. Here, we identify CSNK2/CK2 (casein kinase 2) as a negative regulator of autophagy. Pharmacological inhibition of CSNK2 activity or siRNA-mediated depletion of CSNK2 increased basal autophagic flux in cell lines and primary human lung cells. Vice versa , ectopic expression of CSNK2 reduced autophagic flux. Mechanistically, CSNK2 interacted with the FLN (filamin)-NHL domain-containing tripartite motif (TRIM) family members TRIM2, TRIM3 and TRIM71. Our data show that recruitment of CSNK2 to the C-terminal NHL domain of TRIM3 lead to its robust phosphorylation at serine 661 by CSNK2. A phosphorylation-defective mutant of TRIM3 was unable to reduce autophagosome numbers indicating that phosphorylation by CSNK2 is required for TRIM-mediated autophagy inhibition. All three TRIMs facilitated inactivation of the ULK1-BECN1 autophagy initiation complex by facilitating ULK1 serine 757 phosphorylation. Inhibition of CSNK2 promoted autophagy upon influenza A virus (IAV) and measles virus (MeV) infection. In line with this, targeting of CSNK2 or depletion of TRIM2, TRIM3 or TRIM71 enhanced autophagy-dependent restriction of IAV, MeV and human immunodeficiency virus 1 (HIV-1). Thus, our results identify the CSNK2-TRIM2, -TRIM3, -TRIM71 axis as a key regulatory pathway that limits autophagy. Targeting this axis may allow for therapeutic induction of autophagy against viral infections and in diseases associated with dysregulated autophagy. Abbreviation: ATG5: autophagy related 5; BafA1: bafilomycin A
1 ; BECN1: beclin 1; CCD: coiled-coil domain; CSNK2/CK2: casein kinase 2; CSNK2A1: casein kinase 2 alpha 1; CSNK2A2: casein kinase 2 alpha 2; CSNK2B: casein kinase 2 beta; FLN: filamin; HeLa GL: HeLa cells stably expressing eGFP-LC3B; HIV-1: human immunodeficiency virus 1; IAV: influenza A virus; MAP1LC3B/LC3B: microtubule associated protein 1 light chain 3; MeV: measles virus; MTOR: mechanistic target of rapamycin kinase; RING: really interesting new gene; SQSTM1/p62: sequestosome 1; TRIM: tripartite motif; ULK1: unc-51 like autophagy activating kinase 1.- Published
- 2024
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38. ARF1 prevents aberrant type I interferon induction by regulating STING activation and recycling.
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Hirschenberger M, Lepelley A, Rupp U, Klute S, Hunszinger V, Koepke L, Merold V, Didry-Barca B, Wondany F, Bergner T, Moreau T, Rodero MP, Rösler R, Wiese S, Volpi S, Gattorno M, Papa R, Lynch SA, Haug MG, Houge G, Wigby KM, Sprague J, Lenberg J, Read C, Walther P, Michaelis J, Kirchhoff F, de Oliveira Mann CC, Crow YJ, and Sparrer KMJ
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- Humans, ADP-Ribosylation Factor 1 genetics, ADP-Ribosylation Factor 1 metabolism, Membrane Proteins metabolism, Nucleotidyltransferases genetics, Nucleotidyltransferases metabolism, Signal Transduction, Interferon Type I metabolism
- Abstract
Type I interferon (IFN) signalling is tightly controlled. Upon recognition of DNA by cyclic GMP-AMP synthase (cGAS), stimulator of interferon genes (STING) translocates along the endoplasmic reticulum (ER)-Golgi axis to induce IFN signalling. Termination is achieved through autophagic degradation or recycling of STING by retrograde Golgi-to-ER transport. Here, we identify the GTPase ADP-ribosylation factor 1 (ARF1) as a crucial negative regulator of cGAS-STING signalling. Heterozygous ARF1 missense mutations cause a previously unrecognized type I interferonopathy associated with enhanced IFN-stimulated gene expression. Disease-associated, GTPase-defective ARF1 increases cGAS-STING dependent type I IFN signalling in cell lines and primary patient cells. Mechanistically, mutated ARF1 perturbs mitochondrial morphology, causing cGAS activation by aberrant mitochondrial DNA release, and leads to accumulation of active STING at the Golgi/ERGIC due to defective retrograde transport. Our data show an unexpected dual role of ARF1 in maintaining cGAS-STING homeostasis, through promotion of mitochondrial integrity and STING recycling., (© 2023. Springer Nature Limited.)
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- 2023
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39. Head-to-head comparison of different classes of FAP radioligands designed to increase tumor residence time: monomer, dimer, albumin binders, and small molecules vs peptides.
- Author
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Millul J, Koepke L, Haridas GR, Sparrer KMJ, Mansi R, and Fani M
- Subjects
- Humans, HEK293 Cells, Tissue Distribution, Cell Line, Tumor, Peptides, Cyclic, Positron Emission Tomography Computed Tomography, Gallium Radioisotopes, Albumins chemistry, Peptides
- Abstract
Purpose: Fibroblast activation protein-α (FAP)-targeting radioligands have recently demonstrated high diagnostic potential. However, their therapeutic value is impaired by the short tumor residence time. Several strategies have been tested to overcome this limitation, but a head-to-head comparison has never been done. With the aim to identify strengths and limitations of the suggested strategies, we compared the monomer FAPI-46 versus (a) its dimer (FAPI-46-F1D), (b) two albumin binders conjugates (FAPI-46-Ibu (ibuprofen) and FAPI-46-EB (Evans Blue)), and (c) cyclic peptide FAP-2286., Methods:
177 Lu-labeled ligands were evaluated in vitro in cell lines with low (HT-1080.hFAP) and high (HEK-293.hFAP) humanFAP expression. SPECT/CT imaging and biodistribution studies were conducted in HT-1080.hFAP and HEK-293.hFAP xenografts. The areas under the curve (AUC) of the tumor uptake and tumor-to-critical-organs ratios and the absorbed doses were estimated., Results: Radioligands showed IC50 in the picomolar range. Striking differences were observed in vivo regarding tumor uptake, residence, specificity, and total body distribution. All [177 Lu]Lu-FAPI-46-based radioligands showed similar uptake between the two tumor models. [177 Lu]Lu-FAP-2286 showed higher uptake in HEK-293.hFAP and the least background. The AUC of the tumor uptake and absorbed dose was higher for [177 Lu]Lu-FAPI-46-F1D and the two albumin binder conjugates, [177 Lu]Lu-FAPI-46-Ibu and [177 Lu]Lu-FAPI-46-EB, in HT1080.hFAP xenografts and for [177 Lu]Lu-FAPI-46-EB and [177 Lu]Lu-FAP-2286 in HEK293.hFAP xenografts. The tumor-to-critical-organs AUC values and the absorbed doses were in favor of [177 Lu]Lu-FAP-2286, but tumor-to-kidneys., Conclusion: The study indicated dimerization and cyclic peptide structures as promising strategies for prolonging tumor residence time, sparing healthy tissues. Albumin binding strategy outcome depended on the albumin binding moiety. The peptide showed advantages in terms of tumor-to-background ratios, besides tumor-to-kidneys, but its tumor uptake was FAP expression-dependent., (© 2023. The Author(s).)- Published
- 2023
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40. Performance of peripheral catheters inserted with ultrasound guidance versus landmark technique after a simulation-based mastery learning intervention.
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Feinsmith SE, Amick AE, Feinglass JM, Sell J, Davis EM, Spencer TR, Koepke L, Pastoral J, Wayne DB, and Barsuk JH
- Subjects
- Humans, Retrospective Studies, Catheters, Ultrasonography, Ultrasonography, Interventional methods, Catheterization, Peripheral adverse effects, Catheterization, Peripheral methods
- Abstract
Problem: Ultrasound-guided peripheral intravenous catheter (USGPIV) insertion is an effective method to gain vascular access in patients with difficult intravenous access (DIVA). While USGPIV success rates are reported to be high, some studies have reported a concerning incidence of USGPIV premature failures., Aims: The purpose of this study was to compare differences in USGPIV and landmark peripheral intravenous catheter (PIV) utilization and failure following a hospital-wide USGPIV training program for nurses., Methods: The authors performed a retrospective, electronic medical record review of all USGPIVs and PIVs inserted at a tertiary, urban, academic medical center from September 1, 2018, through September 30, 2019. The primary outcome was differences between USGPIV and PIV time to failure., Results: A total of 43,470 short peripheral intravenous catheters (PIVCs) were inserted in 23,713 patients. Of these, 7972 (16.8%) were USGPIV. At 30 days of follow-up, for PIVCs with an indication for removal documented, USGPIVs had higher Kaplan-Meier survival probabilities than PIVs ( p < 0.001)., Conclusions: The use of simulation-based mastery associated with USGPIVs, demonstrated lower failure rates than standard PIVs after 2 days and USGPIVs exhibited improved survival rates in patients with DIVA. These findings suggest that rigorous simulation-based insertion training demonstrates improved USGPIV survival when compared to traditional PIVCs. SBML is an extremely useful tool to ensure appropriately trained clinicians acquire the necessary knowledge and skillset to improve USGPIV outcomes., Competing Interests: Declaration of conflicting interestsThe author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article: The authors have no relevant financial disclosures to declare. The ultrasound machines were provided to the facility by FUJIFILM-Sonosite. The simulators were donated to the facility by Simulab Corporation.
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- 2023
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41. Interferon antagonists encoded by SARS-CoV-2 at a glance.
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Lee JH, Koepke L, Kirchhoff F, and Sparrer KMJ
- Subjects
- Humans, SARS-CoV-2, Antiviral Agents pharmacology, Antiviral Agents therapeutic use, Immunity, Innate, Interferons genetics, COVID-19
- Abstract
The innate immune system is a powerful barrier against invading pathogens. Interferons (IFNs) are a major part of the cytokine-mediated anti-viral innate immune response. After recognition of a pathogen by immune sensors, signaling cascades are activated that culminate in the release of IFNs. These activate cells in an autocrine or paracrine fashion eventually setting cells in an anti-viral state via upregulation of hundreds of interferon-stimulated genes (ISGs). To evade the anti-viral effect of the IFN system, successful viruses like the pandemic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evolved strategies to counteract both IFN induction and signaling. In fact, more than half of the about 30 proteins encoded by SARS-CoV-2 target the IFN system at multiple levels to escape IFN-mediated restriction. Here, we review recent insights into the molecular mechanisms used by SARS-CoV-2 proteins to suppress IFN production and the establishment of an anti-viral state., (© 2022. The Author(s).)
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- 2023
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42. Reduced replication but increased interferon resistance of SARS-CoV-2 Omicron BA.1.
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Nchioua R, Schundner A, Klute S, Koepke L, Hirschenberger M, Noettger S, Fois G, Zech F, Graf A, Krebs S, Braubach P, Blum H, Stenger S, Kmiec D, Frick M, Kirchhoff F, and Sparrer KM
- Subjects
- Humans, SARS-CoV-2, Antiviral Agents pharmacology, Interferons pharmacology, COVID-19
- Abstract
The IFN system constitutes a powerful antiviral defense machinery. Consequently, effective IFN responses protect against severe COVID-19 and exogenous IFNs inhibit SARS-CoV-2 in vitro. However, emerging SARS-CoV-2 variants of concern (VOCs) may have evolved reduced IFN sensitivity. Here, we determined differences in replication and IFN susceptibility of an early SARS-CoV-2 isolate (NL-02-2020) and the Alpha, Beta, Gamma, Delta, and Omicron VOCs in Calu-3 cells, iPSC-derived alveolar type-II cells (iAT2) and air-liquid interface (ALI) cultures of primary human airway epithelial cells. Our data show that Alpha, Beta, and Gamma replicated to similar levels as NL-02-2020. In comparison, Delta consistently yielded higher viral RNA levels, whereas Omicron was attenuated. All viruses were inhibited by type-I, -II, and -III IFNs, albeit to varying extend. Overall, Alpha was slightly less sensitive to IFNs than NL-02-2020, whereas Beta, Gamma, and Delta remained fully sensitive. Strikingly, Omicron BA.1 was least restricted by exogenous IFNs in all cell models. Our results suggest that enhanced innate immune evasion rather than higher replication capacity contributed to the effective spread of Omicron BA.1., (© 2023 Nchioua et al.)
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- 2023
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43. SARS-CoV-2 Variants of Concern Hijack IFITM2 for Efficient Replication in Human Lung Cells.
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Nchioua R, Schundner A, Kmiec D, Prelli Bozzo C, Zech F, Koepke L, Graf A, Krebs S, Blum H, Frick M, Sparrer KMJ, and Kirchhoff F
- Subjects
- COVID-19 virology, Cell Line, Tumor, Humans, RNA-Binding Proteins genetics, RNA-Binding Proteins metabolism, Virus Internalization, Lung virology, Membrane Proteins genetics, Membrane Proteins metabolism, SARS-CoV-2 genetics, SARS-CoV-2 physiology, Virus Replication
- Abstract
It has recently been shown that an early SARS-CoV-2 isolate (NL-02-2020) hijacks interferon-induced transmembrane proteins (IFITMs) for efficient replication in human lung cells, cardiomyocytes, and gut organoids. To date, several "variants of concern" (VOCs) showing increased infectivity and resistance to neutralization have emerged and globally replaced the early viral strains. Here, we determined whether the five current SARS-CoV-2 VOCs (Alpha, Beta, Gamma, Delta, and Omicron) maintained the dependency on IFITM proteins for efficient replication. We found that depletion of IFITM2 strongly reduces viral RNA production by all VOCs in the human epithelial lung cancer cell line Calu-3. Silencing of IFITM1 had modest effects, while knockdown of IFITM3 resulted in an intermediate phenotype. Strikingly, depletion of IFITM2 generally reduced infectious virus production by more than 4 orders of magnitude. In addition, an antibody directed against the N terminus of IFITM2 inhibited SARS-CoV-2 VOC replication in induced pluripotent stem cell (iPSC)-derived alveolar epithelial type II cells, thought to represent major viral target cells in the lung. In conclusion, endogenously expressed IFITM proteins (especially IFITM2) are critical cofactors for efficient replication of genuine SARS-CoV-2 VOCs, including the currently dominant Omicron variant. IMPORTANCE Recent data indicate that SARS-CoV-2 requires endogenously expressed IFITM proteins for efficient infection. However, the results were obtained with an early SARS-CoV-2 isolate. Thus, it remained to be determined whether IFITMs are also important cofactors for infection of emerging SARS-CoV-2 VOCs that outcompeted the original strains in the meantime. This includes the Omicron VOC, which currently dominates the pandemic. Here, we show that depletion of endogenous IFITM2 expression almost entirely prevents productive infection of Alpha, Beta, Gamma, Delta, and Omicron SARS-CoV-2 VOCs in human lung cells. In addition, an antibody targeting the N terminus of IFITM2 inhibited SARS-CoV-2 VOC replication in iPSC-derived alveolar epithelial type II cells. Our results show that SARS-CoV-2 VOCs, including the currently dominant Omicron variant, are strongly dependent on IFITM2 for efficient replication, suggesting a key proviral role of IFITMs in viral transmission and pathogenicity.
- Published
- 2022
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44. Omicron: What Makes the Latest SARS-CoV-2 Variant of Concern So Concerning?
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Jung C, Kmiec D, Koepke L, Zech F, Jacob T, Sparrer KMJ, and Kirchhoff F
- Subjects
- Genome, Viral, Humans, Immune Evasion, Mutation, Spike Glycoprotein, Coronavirus metabolism, COVID-19 immunology, COVID-19 virology, SARS-CoV-2 genetics, SARS-CoV-2 immunology, SARS-CoV-2 pathogenicity
- Abstract
Emerging strains of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of the coronavirus disease 2019 (COVID-19) pandemic, that show increased transmission fitness and/or immune evasion are classified as "variants of concern" (VOCs). Recently, a SARS-CoV-2 variant first identified in November 2021 in South Africa has been recognized as a fifth VOC, termed "Omicron." What makes this VOC so alarming is the high number of changes, especially in the viral Spike protein, and accumulating evidence for increased transmission efficiency and escape from neutralizing antibodies. In an amazingly short time, the Omicron VOC has outcompeted the previously dominating Delta VOC. However, it seems that the Omicron VOC is overall less pathogenic than other SARS-CoV-2 VOCs. Here, we provide an overview of the mutations in the Omicron genome and the resulting changes in viral proteins compared to other SARS-CoV-2 strains and discuss their potential functional consequences.
- Published
- 2022
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45. Luciferase reporter assays to monitor interferon signaling modulation by SARS-CoV-2 proteins.
- Author
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Hirschenberger M, Hayn M, Laliberté A, Koepke L, Kirchhoff F, and Sparrer KMJ
- Subjects
- Antiviral Agents pharmacology, COVID-19 metabolism, COVID-19 virology, Humans, Luciferases genetics, Promoter Regions, Genetic, RNA, Messenger genetics, SARS-CoV-2 drug effects, Viral Proteins genetics, COVID-19 Drug Treatment, COVID-19 pathology, Gene Expression Regulation, Viral drug effects, Interferons pharmacology, Luciferases metabolism, RNA, Messenger metabolism, SARS-CoV-2 metabolism, Viral Proteins metabolism
- Abstract
We present a protocol for analyzing the impact of SARS-CoV-2 proteins in interferon signaling using luciferase reporter assays. Here, the induction of defined promoters can be quantitatively assessed with high sensitivity and broad linear range. The results are similar to those obtained using qPCR to measure endogenous mRNA induction. The assay requires stringent normalization and confirmation of the results in more physiological settings. The protocol is adaptable for other viruses and other innate immune stimuli. For complete details on the use and execution of this protocol, please refer to Hayn et al. (2021)., Competing Interests: No competing interest to declare., (© 2021 The Author(s).)
- Published
- 2021
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46. Spike residue 403 affects binding of coronavirus spikes to human ACE2.
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Zech F, Schniertshauer D, Jung C, Herrmann A, Cordsmeier A, Xie Q, Nchioua R, Prelli Bozzo C, Volcic M, Koepke L, Müller JA, Krüger J, Heller S, Stenger S, Hoffmann M, Pöhlmann S, Kleger A, Jacob T, Conzelmann KK, Ensser A, Sparrer KMJ, and Kirchhoff F
- Subjects
- Animals, COVID-19 virology, COVID-19 Vaccines, Caco-2 Cells, Cloning, Molecular, HEK293 Cells, Humans, Molecular Dynamics Simulation, Mutation, Replicon, Species Specificity, Stem Cells, Zoonoses, Angiotensin-Converting Enzyme 2 chemistry, Protein Binding, SARS-CoV-2 genetics, SARS-CoV-2 metabolism, Spike Glycoprotein, Coronavirus chemistry, Spike Glycoprotein, Coronavirus genetics
- Abstract
The bat sarbecovirus RaTG13 is a close relative of SARS-CoV-2, the cause of the COVID-19 pandemic. However, this bat virus was most likely unable to directly infect humans since its Spike (S) protein does not interact efficiently with the human ACE2 receptor. Here, we show that a single T403R mutation increases binding of RaTG13 S to human ACE2 and allows VSV pseudoparticle infection of human lung cells and intestinal organoids. Conversely, mutation of R403T in the SARS-CoV-2 S reduces pseudoparticle infection and viral replication. The T403R RaTG13 S is neutralized by sera from individuals vaccinated against COVID-19 indicating that vaccination might protect against future zoonoses. Our data suggest that a positively charged amino acid at position 403 in the S protein is critical for efficient utilization of human ACE2 by S proteins of bat coronaviruses. This finding could help to better predict the zoonotic potential of animal coronaviruses., (© 2021. The Author(s).)
- Published
- 2021
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47. Manipulation of autophagy by SARS-CoV-2 proteins.
- Author
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Koepke L, Hirschenberger M, Hayn M, Kirchhoff F, and Sparrer KM
- Subjects
- Autophagosomes, Autophagy, Humans, Lysosomes, COVID-19, SARS-CoV-2
- Abstract
As part of innate immune defenses, macroautophagy/autophagy targets viruses and viral components for lysosomal degradation and exposes pathogen-associated molecular patterns to facilitate recognition. However, viruses evolved sophisticated strategies to antagonize autophagy and even exploit it to promote their replication. In our recent study, we systematically analyzed the impact of individual SARS-CoV-2 proteins on autophagy. We showed that E, M, ORF3a, and ORF7a cause an accumulation of autophagosomes, whereas Nsp15 prevents the efficient formation of autophagosomes. Consequently, autophagic degradation of SQSTM1/p62 is decreased in the presence of E, ORF3a, ORF7a, and Nsp15. Notably, M does not alter SQSTM1 protein levels and colocalizes with accumulations of LC3B-positive membranes not resembling vesicles. Infection with SARS-CoV-2 prevents SQSTM1 degradation and increases lipidation of LC3B, indicating overall that the infection causes a reduction of autophagic flux. Our mechanistic analyses showed that the accessory proteins ORF3a and ORF7a both block autophagic degradation but use different strategies. While ORF3a prevents the fusion between autophagosomes and lysosomes, ORF7a reduces the acidity of lysosomes. In summary, we found that Nsp15, E, M, ORF3a, and ORF7a of SARS-CoV-2 manipulate cellular autophagy, and we determined the molecular mechanisms of ORF3a and ORF7a.
- Published
- 2021
- Full Text
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48. IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro.
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Prelli Bozzo C, Nchioua R, Volcic M, Koepke L, Krüger J, Schütz D, Heller S, Stürzel CM, Kmiec D, Conzelmann C, Müller J, Zech F, Braun E, Groß R, Wettstein L, Weil T, Weiß J, Diofano F, Rodríguez Alfonso AA, Wiese S, Sauter D, Münch J, Goffinet C, Catanese A, Schön M, Boeckers TM, Stenger S, Sato K, Just S, Kleger A, Sparrer KMJ, and Kirchhoff F
- Subjects
- Amino Acid Sequence, Angiotensin-Converting Enzyme 2 antagonists & inhibitors, Angiotensin-Converting Enzyme 2 metabolism, Antibodies, Neutralizing pharmacology, Antigens, Differentiation metabolism, Binding Sites, COVID-19 virology, Gene Expression Regulation, Host-Pathogen Interactions drug effects, Host-Pathogen Interactions genetics, Humans, Interferon-beta pharmacology, Membrane Proteins antagonists & inhibitors, Membrane Proteins metabolism, Protein Binding, Protein Interaction Domains and Motifs, RNA, Small Interfering genetics, RNA, Small Interfering metabolism, RNA-Binding Proteins antagonists & inhibitors, RNA-Binding Proteins metabolism, SARS-CoV-2 drug effects, SARS-CoV-2 metabolism, Sequence Alignment, Sequence Homology, Amino Acid, Spike Glycoprotein, Coronavirus metabolism, Virus Attachment drug effects, Angiotensin-Converting Enzyme 2 genetics, Antigens, Differentiation genetics, Membrane Proteins genetics, RNA-Binding Proteins genetics, SARS-CoV-2 genetics, Spike Glycoprotein, Coronavirus genetics
- Abstract
Interferon-induced transmembrane proteins (IFITMs 1, 2 and 3) can restrict viral pathogens, but pro- and anti-viral activities have been reported for coronaviruses. Here, we show that artificial overexpression of IFITMs blocks SARS-CoV-2 infection. However, endogenous IFITM expression supports efficient infection of SARS-CoV-2 in human lung cells. Our results indicate that the SARS-CoV-2 Spike protein interacts with IFITMs and hijacks them for efficient viral infection. IFITM proteins were expressed and further induced by interferons in human lung, gut, heart and brain cells. IFITM-derived peptides and targeting antibodies inhibit SARS-CoV-2 entry and replication in human lung cells, cardiomyocytes and gut organoids. Our results show that IFITM proteins are cofactors for efficient SARS-CoV-2 infection of human cell types representing in vivo targets for viral transmission, dissemination and pathogenesis and are potential targets for therapeutic approaches., (© 2021. The Author(s).)
- Published
- 2021
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49. Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities.
- Author
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Hayn M, Hirschenberger M, Koepke L, Nchioua R, Straub JH, Klute S, Hunszinger V, Zech F, Prelli Bozzo C, Aftab W, Christensen MH, Conzelmann C, Müller JA, Srinivasachar Badarinarayan S, Stürzel CM, Forne I, Stenger S, Conzelmann KK, Münch J, Schmidt FI, Sauter D, Imhof A, Kirchhoff F, and Sparrer KMJ
- Subjects
- Animals, Antiviral Agents pharmacology, Autophagosomes immunology, Autophagy immunology, COVID-19 immunology, Cell Line, Chlorocebus aethiops, Exoribonucleases immunology, HEK293 Cells, HeLa Cells, Humans, Immune Evasion, Immunity, Innate, Interferon Type I metabolism, Interferons metabolism, Receptor, Interferon alpha-beta antagonists & inhibitors, Receptor, Interferon alpha-beta immunology, SARS-CoV-2 pathogenicity, Vero Cells, Viral Nonstructural Proteins immunology, COVID-19 virology, SARS-CoV-2 immunology, Viral Proteins immunology
- Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) evades most innate immune responses but may still be vulnerable to some. Here, we systematically analyze the impact of SARS-CoV-2 proteins on interferon (IFN) responses and autophagy. We show that SARS-CoV-2 proteins synergize to counteract anti-viral immune responses. For example, Nsp14 targets the type I IFN receptor for lysosomal degradation, ORF3a prevents fusion of autophagosomes and lysosomes, and ORF7a interferes with autophagosome acidification. Most activities are evolutionarily conserved. However, SARS-CoV-2 Nsp15 antagonizes IFN signaling less efficiently than the orthologs of closely related RaTG13-CoV and SARS-CoV-1. Overall, SARS-CoV-2 proteins counteract autophagy and type I IFN more efficiently than type II or III IFN signaling, and infection experiments confirm potent inhibition by IFN-γ and -λ1. Our results define the repertoire and selected mechanisms of SARS-CoV-2 innate immune antagonists but also reveal vulnerability to type II and III IFN that may help to develop safe and effective anti-viral approaches., Competing Interests: Declaration of interests F.I.S. is a co-founder of DiosCURE Therapeutics SE and a consultant to IFM Therapeutics., (Copyright © 2021 The Author(s). Published by Elsevier Inc. All rights reserved.)
- Published
- 2021
- Full Text
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50. The antiviral activities of TRIM proteins.
- Author
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Koepke L, Gack MU, and Sparrer KM
- Subjects
- Animals, Autophagy immunology, Cytokines immunology, Humans, Antiviral Agents metabolism, Tripartite Motif Proteins genetics, Tripartite Motif Proteins metabolism
- Abstract
Tripartite motif (TRIM) proteins are a highly versatile family of host-cell factors that play an integral role in the mammalian defense against pathogens. TRIM proteins regulate either transcription-dependent antiviral responses such as pro-inflammatory cytokine induction, or they modulate other important cell-intrinsic defense pathways like autophagy. Additionally, TRIM proteins exert direct antiviral activity whereby they antagonize specific viral components through diverse mechanisms. Here, we summarize the latest discoveries on the molecular mechanisms of antiviral TRIM proteins and also discuss current and future trends in this fast-evolving field., (Copyright © 2020 Elsevier Ltd. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
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