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To evaluate the efficacy of the enterokinetic prucalopride (resolor) in patients with chronic constipation.The effect of treatment with prucalopride (resolor) in 109 patients with chronic constipation was analyzed.The effect was noted in 82% of the patients; 61 patients were fully satisfied with treatment results. Among the adverse reactions, headache that was particularly significant on the first days of use, diarrhea, and cramping abdominal pain were reported by 35, 17, and 13% of the included patients, respectively. The authors' experience with prucalopride demonstrated that the patients with chronic constipation displayed the good efficacy of the drug in both the frequency of stool and the elimination of all other constipation symptoms (straining effort, incomplete bowel emptying sensation, solid stool, bloating), and its good tolerability.Prucalopride (resolor) exerts a predictable effect, can extend a physician's capacity to arrest chronic constipation, and, when the drug is used, requires no long-term dose adjustment.

Certain general and local factors can increase the probability of complications of gastric ulcer (GU) and addition of conditionally pathogenic fungi (CPF), which requires direct examination of GU patients for fungous infections. Considering that addition of active CPF forms to ulcerous defects lead to enlargement and deepening of ulcers and postpones their healing, all patients with GU complicated by addition of CPF were administered antifungal drugs. A comparative study found no significant differences in the efficacy of eradication of fungal infection between system (resorbable) and luminal (non-resorbable) antimycotics.

To assess the risk factors of mycotic infection on the gastric mucosa (GM) in patients with gastric peptic ulcer, 34 patients who had much mycelium on the bottom of the defect and 122 patients without fungal infection were examined in detail. The occurrence of mycotic infection in patients with ulcerative defects was associated with a variety of both local (the depth, number, large sizes of defects, diminished gastric acid-producing ability) and total (age, trophological insufficiency, iron-deficiency anemia, oral mycotic disease, autonomic dysfunction) factors. Mycotic involvement of ulcerative defects is secondary and regarded as a focal manifestation of mycotic infection. The likely impact of mycotic infection on the quality of ulcerative defect scarring makes us consider whether antimycotic agents should be added to antiulcerative therapy.

The purpose of the study was to make a comparative medical and economic analysis of the application of Rabeprazole (Pariet) and Omeprazole generic in a seven-day eradication therapy.

Prevalence of gall bladder's polipoid formations is 4.3% by ultrasonographic (US) examinations of gastroenterological patients. So tactics of such patients management is necessary. Usual US examination doesn't always allow differentiate real polips and cholesterol's polips. The real ones demand active surgery. The positive reactions to ursosan's treatment testifies to cholesterol gall bladder's formations.