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Background: Overall survival (OS) is the most important endpoint in oncology clinical trials, however, its use is limited by sufficient sample size and follow-up times. Progression-free survival (PFS) is an established surrogate for OS, based on the reliable detection of disease progression through [for full text, please go to the a.m. URL], 65th Annual Meeting of the German Association for Medical Informatics, Biometry and Epidemiology (GMDS), Meeting of the Central European Network (CEN: German Region, Austro-Swiss Region and Polish Region) of the International Biometric Society (IBS)

Meningeome sind häufige intrakranielle Tumoren, die durch die Entartung von Zellen der Arachnoidea mater entstehen. Klinisch manifestieren sie sich in Form von Kopfschmerzen, fokalen oder generalisierten Krampfanfällen oder kompressionsbedingten neurologischen Ausfällen. Über 90% der in der Regel langsam wachsenden Meningeome sind benigne. Bei den meisten symptomatischen Patienten wird die Tumorresektion in kurativer oder zumindest symptomlindernder Intention angestrebt. Bei subtotaler Resektion besteht die Möglichkeit einer adjuvanten Bestrahlung. Eine stereotaktische Radiotherapie kann jedoch auch als Ersttherapie bei Patienten erfolgen, die sich durch hohes Alter oder Tumoren in eloquenten oder chirurgisch schlecht erreichbaren Arealen nicht für eine neuro-chirurgische Operation qualifizieren. Bei nicht resezierbaren Tumoren oder falls alle vorherigen Therapien keinen Erfolg gebracht haben, kann eine Hormon- oder Chemotherapie in Erwägung gezogen werden.

Objective: Among calcified spinal lesions, herniated disc fragments, synovial cysts, neurinomas, and psammomatous meningiomas should be taken into account. Furthermore, epidural abcesses and old calcified haematomas can appear calcified. Calcifying pseudoneoplasms of the neuraxis (CAPNON) constitute[for full text, please go to the a.m. URL], 64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Objective: The Piezosurgery device is already well known in the domain of dental and implant surgery. The field of published indications for this tool became larger and larger by time. The main advantages for its use in neurosurgery seem to be the soft tissue protection as well as a more aesthetic outcome[for full text, please go to the a.m. URL], 64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Objective: Calcifying pseudoneoplasms of the neuraxis (CAPNON) are rare, benign tumours of the central nervous system (CNS). Since their initial description in 1978, only 20 intracranial cases have been reported in case reports or case series. Method: We report two further cases with histopathologically[for full text, please go to the a.m. URL], 64. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC)

Objective: The aim of this study was to approve the feasibility of an endoscopic transmaxillary approach to the orbit in human cadaveric heads, using a pituitary endoscope. During the last years, alternative endoscopic approaches to the clivus or anterior skull base have been developed; endoscopic pituitary[for full text, please go to the a.m. URL], 60. Jahrestagung der Deutschen Gesellschaft für Neurochirurgie (DGNC), Joint Meeting mit den Benelux-Ländern und Bulgarien

We have already had the opportunity to demonstrate to what extent the distinction between “common” and “specialised” lexicon is a crucial key to the evaluation of processes of lexical substitution within Sicilian-Albanian contexts. Unlike to what happens to the dynamics of contact among the varieties of Italo-Romance repertoires (where dialectal variants seem to be better preserved in some experiential fields that are typical of traditional activities), in the Sicilian-Albanian context, the original (Albanian) lexicon seems to be more preserved within the setting of specific experiencial fields of a greater community sharing (and, substantially, in the urban context). Instead, the concepts of reduced community circulation (more specifically embedded within the framework of highly isolated rural environments) are commonly affected by lexical innovations resulting, in this case, from the contacts established with the Italo-Romance varieties. This study, which examines the lexicon of the Piana degli Albanesi arbëreshe variety relating to the semantic field of ‘animals’, aims, not only to share a series of lexical information, somewhat prone to obsolescence, but also to additionally verify the heuristic value of a sectorial approach to the analysis of language contact in the Italo-Albanian context.