35 results on '"L, Jiménez Montañés"'
Search Results
2. Constricción precoz del ductus arterioso
- Author
-
D. Lerma Puertas, L. Jiménez Montañés, Ariadna Ayerza Casas, M. López Ramón, and M. D. García de la Calzada
- Subjects
business.industry ,Pediatrics, Perinatology and Child Health ,Medicine ,business ,Pediatrics ,RJ1-570 - Published
- 2015
3. Premature constriction of the ductus arteriosus
- Author
-
M. López Ramón, D. Lerma Puertas, M. D. García de la Calzada, Ariadna Ayerza Casas, and L. Jiménez Montañés
- Subjects
medicine.medical_specialty ,Pregnancy ,business.industry ,Gestational age ,Retrospective cohort study ,medicine.disease ,Pediatrics ,RJ1-570 ,Constriction ,Text mining ,medicine.anatomical_structure ,Management of Technology and Innovation ,Internal medicine ,Ductus arteriosus ,Cardiology ,Medicine ,Ultrasonography ,business - Published
- 2015
4. Afectación cardiovascular en el síndrome de Loeys-Dietz
- Author
-
M. López Ramón, Ariadna Ayerza Casas, L. Jiménez Montañés, and D. Palanca Arias
- Subjects
0301 basic medicine ,03 medical and health sciences ,0302 clinical medicine ,Pediatrics, Perinatology and Child Health ,030204 cardiovascular system & hematology ,030105 genetics & heredity ,Pediatrics ,RJ1-570 - Published
- 2017
5. [Premature constriction of the ductus arteriosus]
- Author
-
A, Ayerza Casas, L, Jiménez Montañés, M, López Ramón, D, Lerma Puertas, and M D, García de la Calzada
- Subjects
Pregnancy ,Humans ,Female ,Gestational Age ,Constriction, Pathologic ,Ductus Arteriosus ,Ultrasonography, Prenatal ,Retrospective Studies - Published
- 2014
6. [The use of corticosteroids in cryptogenic palsy of the third cranial nerves. A case report]
- Author
-
L, Jiménez-Montañés, M, Martínez-Fernández, M, Elizalde-Usechi, and J, López-Pisón
- Subjects
Ophthalmoplegia ,Oculomotor Nerve ,Adrenal Cortex Hormones ,Child, Preschool ,Humans ,Prednisone ,Female - Abstract
In spite of the rarity of isolated paralysis of the third cranial nerves in infancy, we present an acquired cryptogenic case which had an excellent, rapid response to treatment with corticosteroids started three months after onset of the condition.A girl aged three and a half years, with no significant past clinical history, presented with a third cranial nerve syndrome of sudden onset, with divergent squint and right ptosis, but no changes in pupil reactivity. All the complementary tests done were normal. After three months of observation, since the condition persisted, treatment was started with oral prednisone 2 mg/kg/day for three months. The ptosis disappeared in two weeks, and two years after treatment was stopped has not reappeared. The absence of pain would suggest that this was not a Tolosa-Hunt syndrome, although pain-free episodes have been described. The absence of alteration in pupil reactions is against, although does not exclude, compression of the third cranial nerve. This finding, together with the spectacular response to corticosteroids would support the diagnosis of inflammation limited to the motor fibres, probably due to a viral infection.We conclude that corticosteroids may be considered in the treatment of cryptogenic cranial neuropathy, once other possible aetiologies have been excluded, with the object of modulation of the theoretical immune mechanisms involved.
- Published
- 2000
7. Infarto agudo de miocardio por cocaína
- Author
-
L. Jiménez Montañés, R. Lahoz Ramo, F. Hermogenes Prada Martínez, and I. Jordán García
- Subjects
business.industry ,Pediatrics, Perinatology and Child Health ,Medicine ,business ,Pediatrics ,RJ1-570 - Published
- 2009
8. [Severe toxoplasmosis: two case reports]
- Author
-
J M, Jiménez Hereza, L, Jiménez Montañés, V, Rebage Moisés, L, Roc Alfaro, M J, Edo Gimeno, M, Elizalde Usechi, C, Ferrer Novellas, and A, Marco Tello
- Subjects
Male ,Infant, Newborn ,Brain ,Calcinosis ,Humans ,Female ,Tomography, X-Ray Computed ,Toxoplasmosis, Congenital - Published
- 1996
9. Uso de corticosteroides en la parálisis criptogénica del III par craneal. A propósito de un caso
- Author
-
J López-Pisón, M Martínez-Fernández, L Jiménez-Montañés, and M Elizalde-Usechi
- Subjects
medicine.medical_specialty ,Palsy ,Oculomotor nerve ,business.industry ,General Medicine ,Pupil ,Surgery ,Ptosis ,Prednisone ,Paralysis ,medicine ,Neurology (clinical) ,medicine.symptom ,business ,Rapid response ,Sudden onset ,medicine.drug - Abstract
Introduction In spite of the rarity of isolated paralysis of the third cranial nerves in infancy, we present an acquired cryptogenic case which had an excellent, rapid response to treatment with corticosteroids started three months after onset of the condition. Clinical case A girl aged three and a half years, with no significant past clinical history, presented with a third cranial nerve syndrome of sudden onset, with divergent squint and right ptosis, but no changes in pupil reactivity. All the complementary tests done were normal. After three months of observation, since the condition persisted, treatment was started with oral prednisone 2 mg/kg/day for three months. The ptosis disappeared in two weeks, and two years after treatment was stopped has not reappeared. The absence of pain would suggest that this was not a Tolosa-Hunt syndrome, although pain-free episodes have been described. The absence of alteration in pupil reactions is against, although does not exclude, compression of the third cranial nerve. This finding, together with the spectacular response to corticosteroids would support the diagnosis of inflammation limited to the motor fibres, probably due to a viral infection. Conclusion We conclude that corticosteroids may be considered in the treatment of cryptogenic cranial neuropathy, once other possible aetiologies have been excluded, with the object of modulation of the theoretical immune mechanisms involved.
- Published
- 1999
10. Brugada Syndrome and Pulmonary Atresia with Intact Interventricular Septum: Fortuitous Finding or New Genetic Connection?
- Author
-
Fogaça-da-Mata M, Martínez-Barrios E, Jiménez-Montañés L, Cruzalegui J, Chipa-Ccasani F, Greco A, Cesar S, Díez-Escuté N, Cerralbo P, Zschaeck I, Clavero Adell M, Ayerza-Casas A, Palanca-Arias D, López M, Campuzano O, Brugada J, and Sarquella-Brugada G
- Subjects
- Humans, Male, Child, Preschool, Heart Defects, Congenital genetics, Heart Defects, Congenital pathology, Ventricular Septum pathology, Pulmonary Atresia genetics, Pulmonary Atresia pathology, Brugada Syndrome genetics, Brugada Syndrome pathology, NAV1.5 Voltage-Gated Sodium Channel genetics
- Abstract
Brugada syndrome is a rare arrhythmogenic syndrome associated mainly with pathogenic variants in the SCN5A gene. Right ventricle outflow tract fibrosis has been reported in some cases of patients diagnosed with Brugada syndrome. Pulmonary atresia with an intact ventricular septum is characterized by the lack of a functional pulmonary valve, due to the underdevelopment of the right ventricle outflow tract. We report, for the first time, a 4-year-old boy with pulmonary atresia with an intact ventricular septum who harbored a pathogenic de novo variant in SCN5A , and the ajmaline test unmasked a type-1 Brugada pattern. We suggest that deleterious variants in the SCN5A gene could be implicated in pulmonary atresia with an intact ventricular septum embryogenesis, leading to overlapping phenotypes.
- Published
- 2024
- Full Text
- View/download PDF
11. Early assessment of cardiomyopathy in Duchenne patients by means of longitudinal strain echocardiography.
- Author
-
Clavero-Adell M, Ayerza-Casas A, Palanca-Arias D, López-Ramón M, Jiménez-Montañés L, and Olmos S
- Subjects
- Humans, Male, Ventricular Function, Left, Cross-Sectional Studies, Stroke Volume, Case-Control Studies, Prospective Studies, Bayes Theorem, Echocardiography, Muscular Dystrophy, Duchenne complications, Muscular Dystrophy, Duchenne diagnosis, Ventricular Dysfunction, Left diagnostic imaging, Ventricular Dysfunction, Left etiology, Cardiomyopathies diagnostic imaging, Cardiomyopathies etiology
- Abstract
Introduction: The diagnosis of Duchenne-linked cardiomyopathy may be challenging. Conventional echocardiographic measurements typically show deterioration beyond the second decade. Global longitudinal strain has been proposed as an earlier marker than left ventricular ejection fraction., Material and Methods: A prospective, observational, cross-sectional, case-control study was carried out. Both Duchenne patients and control subjects underwent transthoracic echocardiogram in order to assess left ventricle function. Bayesian linear regression was the main tool for inference. Age effects were parameterised by means of a spline function because of its simplicity to characterise continuous variables and smooth contributions. The posterior distribution of the marginal age effects was used to assess the earliest age of deterioration of each marker., Results: Sixteen Duchenne patients and twenty-two healthy male subjects were enrolled. On overage, cardiac function measures were found for ejection fraction and longitudinal strain among different groups. Age effects on global longitudinal strain are more reliably found at ages of 6 and above, while ejection fraction starts to deteriorate at an older age. Progressive left ventricular dysfunction in Duchenne patients is one of the key issues and starts at an early age with subtle symptoms., Conclusion: This cross-sectional study provides supporting evidence that global longitudinal strain is an earlier marker of disease progression than ejection fraction in Duchenne patients.
- Published
- 2024
- Full Text
- View/download PDF
12. Takayasu's arteritis as an incidental finding in a patient with celiac disease: the importance of positron emission computed tomography.
- Author
-
Moreno-Sánchez A, Molina-Herranz D, Aguilar-de-la-Red Y, Jiménez-Montañés L, Medrano-SanIldefonso M, and García-Romero R
- Subjects
- Humans, Female, Child, Adolescent, Positron Emission Tomography Computed Tomography, Electrons, Incidental Findings, Takayasu Arteritis diagnosis, Takayasu Arteritis diagnostic imaging, Celiac Disease complications, Celiac Disease diagnosis
- Abstract
Background: Takayasu arteritis is a large-vessel vasculitis which affects large-caliber elastic arteries, primarily the aorta and its main branches. It mainly affects women between 20-30 years, so it is rare in children., Case Report: We describe the case of a 15-year-old female who was followed up since she was 9 years old due to celiac disease. At the age of 13, anaemia of chronic disorders associated to elevated C-reactive protein and erythrocyte sedimentation were detected. The patient remained asymptomatic. After excluding other diseases, we requested a positron emission computed tomography (PET-CT); lesions compatible with large-vessel vasculitis were detected. Cardiology evaluation showed an aneurysm in the right coronary artery. Angio-CT suggested Takayasu type III arteritis., Conclusions: The delay in the diagnosis of Takayasu arteritis in pediatric patients is quite common. In this case, we have found phase II lesions, with no previous phase I symptoms. However, PET-CT allowed the diagnosis of vasculitis, key to the diagnosis of the patient., (Copyright: © 2023 Permanyer.)
- Published
- 2023
- Full Text
- View/download PDF
13. Isolated fetal pericardial effusion follow-up: Should we worry?
- Author
-
Hidalgo Sanz J, Fernández Ventureira V, Palanca Arias D, Pérez Pérez P, Jiménez Montañés L, and AyerzaCasas A
- Subjects
- Female, Humans, Hydrops Fetalis, Infant, Newborn, Pregnancy, Prenatal Diagnosis, Ultrasonography, Prenatal, Chromosome Disorders, Pericardial Effusion diagnosis, Pericardial Effusion epidemiology, Pericardial Effusion etiology
- Abstract
Introduction and Objectives: Fetal pericardial effusion appears in different pathologies such as hydrops fetalis, heart structural or rhythm alterations, however, it can be observed in isolation but an increase in its incidence has been observed in relation to the presence of severe pathologies., Methods: Analysis of all cases of IFPE detected in Aragon and assessed in a cardiological consultation for prenatal diagnosis of a tertiary hospital collected over ten years, as well as the evolution of the patients to the present., Results: A sample of 38 fetuses was obtained from 37 pregnant women diagnosed with DPFA with spontaneous resolution in 86.8%. Two abortions (voluntary interruptions after prenatal diagnosis of 22q13 deletion and primary infection by cytomegalovirus) and one spontaneous fetal death were recorded. Pathological alterations were observed in 10/38 newborns: two patients with metabolic disease, two patients with chromosomopathies, one patient with pulmonary hypoplasia and unilateral hydronephrosis, one patient with hypertrophic cardiomyopathy, and four patients studied for alterations in psychomotor development and/or congenital ophthalmological or hearing disorders. The overall morbidity rate was 34.2% and death rate 15.7%. The detection of other ultrasound alterations and the alteration in the first trimester screening were significantly associated with the presence of pathology., Conclusions: IFPE has been classically associated with a good prognosis, although it is sometimes related to clinical entities with high morbidity and mortality: more than a third of the patients in our sample are affected. An exhaustive pre and postnatal follow-up of these cases is recommended in order to perform an early intervention., (Copyright © 2022 Asociación Española de Pediatría. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2022
- Full Text
- View/download PDF
14. Brugada phenocopy in a child with pediatric inflammatory multisystemic syndrome caused by SARS-CoV-2.
- Author
-
Santiago-Cortés R, Clavero-Adell M, Palanca-Arias D, Jiménez-Montañés L, López-Ramón M, and Ayerza-Casas A
- Subjects
- Child, Electrocardiography, Humans, Phenotype, SARS-CoV-2, Brugada Syndrome diagnosis, Brugada Syndrome etiology, COVID-19
- Published
- 2022
- Full Text
- View/download PDF
15. Atrial flutter without structural heart disease in pediatrics: a retrospective review of cases in the Hospital Infantil Miguel Servet, Zaragoza, Spain.
- Author
-
Moliner-Morón T, Santiago-Cortés R, Ayerza-Casas A, Clavero-Adell M, Jiménez-Montañés L, and Palanca-Arias D
- Subjects
- Male, Infant, Newborn, Pregnancy, Female, Child, Humans, Child, Preschool, Retrospective Studies, Spain epidemiology, Anti-Arrhythmia Agents therapeutic use, Treatment Outcome, Hospitals, Atrial Flutter epidemiology, Atrial Flutter therapy, Atrial Flutter diagnosis
- Abstract
Background: Atrial flutter is a rare condition in pediatrics that usually occurs as a late complication after surgery for congenital heart diseases, although it can also appear in structurally normal hearts., Clinical Cases: We conducted a retrospective study of cases of atrial flutter with no structural heart disease diagnosed in a pediatric population (between 0 and 15 years of age) during 2015-2021 in a tertiary hospital. A total of seven cases were diagnosed, with a clear predominance of males (6/7). Of the seven patients, five debuted in the perinatal period: two were diagnosed at 20 and 36 hours of life, and three, prenatally. Among these perinatal cases, more than half (3/5) were preterm. The treatment was electrical cardioversion. The evolution was satisfactory in these cases, and there were no tachycardias in their subsequent development. In contrast, when the debut occurred at a later age (5-7 years), it was associated with channelopathy (Brugada syndrome and catecholaminergic polymorphic ventricular tachycardia), and electrical ablation of the ectopic focus was required due to poor response to pharmacological treatment., Conclusions: This study confirms the low incidence of this pathology in pediatrics and the benignity and good prognosis of neonatal flutter in most cases. The prognosis worsens when atrial flutter is diagnosed in older children, and the probability of concomitant associated heart disease increases., (Copyright: © 2022 Permanyer.)
- Published
- 2022
- Full Text
- View/download PDF
16. Spanish registry of percutaneous VSD closure with NitOcclud Lê VSD Coil device: lessons learned after more than a hundred implants.
- Author
-
Solana-Gracia R, Mendoza Soto A, Carrasco Moreno JI, Del Cerro Marín MJ, Gutiérrez-Larraya Aguado F, Coserría Sánchez JF, Blanco Mata R, Prada Martínez FH, Pan Álvarez-Ossorio M, Jiménez Montañés L, Pérez de Prado A, Rodríguez Vázquez Del Rey MDM, Gutiérrez García H, Velasco Bayón JM, and Zunzunegui Martínez JL
- Subjects
- Humans, Registries, Reproducibility of Results, Retrospective Studies, Treatment Outcome, Cardiac Catheterization, Heart Septal Defects, Ventricular surgery
- Abstract
Introduction and Objectives: The NitOcclud Lê VSD Coil was specifically designed for transcatheter occlusion of ventricular septal defects (VSD) and became available for this purpose in August 2010. Our objective was to describe the Spanish experience of this technique and analyze its reliability and short- to mid-term efficacy., Methods: National multicenter observational study, which retrospectively recruited all patients (of any age) with VSD (of any location or type) who underwent percutaneous NitOcclud occlusion, using an intention-to-treat analysis, until January 2019., Results: A total of 117 attempts were made to implant at least 1 NitOcclud in 116 patients in 13 institutions. The median [range] age and weight was 8.6 [0.4-69] years and 27 [5.8-97] kg, respectively. In 99 patients (85%), the VSD was an isolated congenital defect. The location was perimembranous in 95 (81%), and 74 (63%) of them were aneurysmatic. The mean fluoroscopy time was 34 [11.4-124] minutes. Of the 117 attempts, 104 were successful (89%) with a follow-up of 31.4 [0.6-59] months. At the last review, final complete occlusion of the defect without residual shunt or with only a minimal shunt was achieved in 92.3% (no shunt, n=73; trivial shunt, n=23). Four patients required a second procedure for residual shunt occlusion. Two devices had to be surgically explanted due to severe hemolysis. There were no deaths or other major complications., Conclusions: The NitOcclud device can be used successfully for a wide anatomical spectrum of VSD. The main issue is residual shunt, but its incidence decreases over time. The incidence of hemolysis was very low and no permanent changes were detected in atrioventricular conduction., (Copyright © 2020 Sociedad Española de Cardiología. Published by Elsevier España, S.L.U. All rights reserved.)
- Published
- 2021
- Full Text
- View/download PDF
17. [Isolated fetal pericardial effusion follow-up: Should we worry?]
- Author
-
Hidalgo Sanz J, Fernández Ventureira V, Palanca Arias D, Pérez Pérez P, Jiménez Montañés L, and Ayerza Casas A
- Abstract
Introduction and Objectives: Fetal pericardial effusion appears in different pathologies such as hydrops fetalis, heart structural or rhythm alterations, however, it can be observed in isolation but an increase in its incidence has been observed in relation to the presence of severe pathologies., Methods: Analysis of all cases of IFPE detected in Aragon and assessed in a cardiological consultation for prenatal diagnosis of a tertiary hospital collected over 10years, as well as the evolution of the patients to the present., Results: A sample of 38 fetuses was obtained from 37 pregnant women diagnosed with DPFA with spontaneous resolution in 86.8%. Two abortions (voluntary interruptions after prenatal diagnosis of 22q13 deletion and primary infection by cytomegalovirus) and one spontaneous fetal death were recorded. Pathological alterations were observed in 10/38 newborns: 2patients with metabolic disease, 2patients with chromosomopathies, one patient with pulmonary hypoplasia and unilateral hydronephrosis, one patient with hypertrophic cardiomyopathy, and 4patients studied for alterations in psychomotor development and/or congenital ophthalmological or hearing disorders. The overall morbidity rate was 34.2% and death rate 15.7%. The detection of other ultrasound alterations and the alteration in the first trimester screening were significantly associated with the presence of pathology., Conclusions: IFPE has been classically associated with a good prognosis, although it is sometimes related to clinical entities with high morbidity and mortality: more than a third of the patients in our sample are affected. An exhaustive pre- and posnatal follow-up of these cases is recommended in order to perform an early intervention., (Copyright © 2021. Publicado por Elsevier España, S.L.U.)
- Published
- 2021
- Full Text
- View/download PDF
18. Cardiac dextroposition associated to Poland syndrome.
- Author
-
Corella Aznar EG, Ayerza Casas A, Palanca Arias D, and Jiménez Montañés L
- Subjects
- Humans, Dextrocardia diagnostic imaging, Poland Syndrome diagnosis
- Published
- 2021
- Full Text
- View/download PDF
19. [Body composition evaluation by anthropometry and bioelectrical impedance analysis in childhood acute leukemia survivors].
- Author
-
Corella Aznar E, Ayerza Casas A, Ros Arnal I, Muñoz Mellado A, Jiménez Montañés L, and Samper Villagrasa P
- Subjects
- Acute Disease, Adiposity, Adolescent, Body Mass Index, Cardiovascular Diseases epidemiology, Child, Child, Preschool, Combined Modality Therapy, Cross-Sectional Studies, Female, Humans, Hypertension epidemiology, Infant, Leukemia complications, Leukemia therapy, Lipids blood, Male, Obesity epidemiology, Prevalence, Risk Factors, Sarcopenia epidemiology, Sarcopenia etiology, Spain epidemiology, Anthropometry, Body Composition, Cancer Survivors statistics & numerical data, Electric Impedance, Leukemia epidemiology
- Abstract
Introduction: Background: survivors of childhood acute leukemia are at risk for obesity. The purpose was to evaluate the different clinical measurements of body composition and to compare with body mass index (BMI). Methods: cross-sectional study of 39 survivors with more than ten years of survivorship since diagnosis. Anthropometry and body composition accuracy measurements were determined and also obesity risk factors. Results: obesity prevalence by body fat percentage were: 38.5% for BMI; 46.1% for waist circumference; 51.3% for skinfolds and 56.4% for bioelectrical impedance analysis (BIA). There was a good correlation among the measurements, but BMI underestimated the percent body fat among childhood leukemia survivors in comparison with: waist circumference (-1.03 ± 2.01), skinfolds (-2.95 ± 5.78) and BIA (-3.78 ± 7.4), and this bias appears to be more variable with increasing percent of body fat > 30%. Three patients showed sarcopenia and only one sarcopenic obesity. Waist circumference fat mass was the better predictor of cardiovascular risk factors (LDL-cholesterol: r = 0.703; HDL-cholesterol: r = -0.612; p < 0.05 and hypertension: OR 4.17; IC 95%: 1.012-19.3). Obesity risk factors were: female sex, high-risk tumor, radiotherapy and stem cell transplantation. Conclusions: BMI underestimates obese childhood leukemia survivors in comparison with waist circumference, skinfolds and bioelectrial impedance analysis. BMI use could misclassify obese survivors as non-obese. Female sex, high tumoral risk and coadyuvant treatments (radiotherapy and stem cell transplant) are risk factors for adiposity.
- Published
- 2020
- Full Text
- View/download PDF
20. [Arterial tortuosity syndrome in a paediatric patient].
- Author
-
Palanca Arias D, Ayerza Casas A, Gutiérrez Alonso C, and Jiménez Montañés L
- Subjects
- Angiography methods, Arteries diagnostic imaging, Arteries physiopathology, Child, Preschool, Female, Humans, Joint Instability physiopathology, Magnetic Resonance Imaging methods, Skin Diseases, Genetic physiopathology, Vascular Malformations physiopathology, Arteries abnormalities, Joint Instability diagnostic imaging, Skin Diseases, Genetic diagnostic imaging, Vascular Malformations diagnostic imaging
- Published
- 2020
- Full Text
- View/download PDF
21. Evolution of strain and strain rate values throughout gestation in healthy fetuses.
- Author
-
Clavero Adell M, Ayerza Casas A, Jiménez Montañés L, Palanca Arias D, López Ramón M, Alcalá Nalvaiz JT, and Samper Villagrasa P
- Subjects
- Adaptation, Physiological, Cross-Sectional Studies, Fetal Heart physiology, Gestational Age, Humans, Predictive Value of Tests, Reference Values, Reproducibility of Results, Retrospective Studies, Echocardiography, Fetal Heart diagnostic imaging, Ultrasonography, Prenatal methods, Ventricular Function, Left, Ventricular Function, Right
- Abstract
Myocardial deformation by speckle tracking echocardiography is a novel method for evaluating cardiac function. To test the hypothesis that right ventricular and left ventricular function have age-specific patterns of development, we tracked the evolution of ventricular strain mechanics by speckle tracking echocardiography in the fetus. We conducted a retrospective cross sectional echocardiography study in 154 healthy fetuses, and characterized cardiac function by measuring right and left ventricles global longitudinal strain and strain rate. Comparison of the data of both ventricles according to gestational age was carried out. The magnitudes of right and left ventricle global longitudinal strain show wide range values and decreased throughout gestation. Strain values are higher in left ventricle compared to the right one throughout pregnancy. Strain rate values were similar over gestation in each ventricle, but the magnitudes declined overtime in the right and left ventricle. The maturational patterns of left and right strain are gestational specific. With accepted physiological maturation patterns in healthy subjects, these myocardial deformation parameters can provide a valid basis that allows comparison between health and disease.
- Published
- 2020
- Full Text
- View/download PDF
22. [Brain natriuretic peptide as a marker of digestive evolution in the premature newborn].
- Author
-
Montaner Ramón A, Serrano Viñuales I, Jiménez Montañés L, Ruiz de la Cuesta Martín C, Samper Villagrasa MP, and Rite Gracia S
- Subjects
- Biomarkers blood, Ductus Arteriosus, Patent complications, Female, Humans, Infant, Newborn, Male, Parenteral Nutrition, Retrospective Studies, Risk, Weight Gain, Digestive System growth & development, Infant, Premature, Natriuretic Peptide, Brain blood, Peptide Fragments blood
- Abstract
Introduction: Background and objective: hemodynamically significant patent ductus arteriosus (HS-PDA) is associated with an increased risk of necrotizing enterocolitis (NEC) and worse enteral tolerance in preterm newborns (PN). An association has been demonstrated between brain natriuretic propeptide (proBNP) and HS-PDA. Our objective was to analyze the relationship between proBNP levels and enteral tolerance, NEC risk and weight gain in PN. Material and methods: a retrospective study was performed in neonates born before 32 weeks' gestation or with birth weight below 1500 grams, in whom proBNP determination and echocardiography were performed at 48 to 72 h of life. Results: 117 patients were included. 65.8% had a HS-PDA and 9.4% had an outcome of NEC. HS-PDA was associated with longer duration of parenteral nutrition (p < 0.001), a confirmed NEC (p = 0.006) and worse weight gain during admission (p < 0.001). ProBNP levels were associated to NEC (no NEC 12189.5 pg / mL, range 654-247986; NEC 41445 pg/mL, range 15275-166172, p < 0.001). No association was found with the rest of gastrointestinal outcomes. Multivariate logistic regression analysis showed a significant association of NEC with gestational age and proBNP above 22,400 pg/mL (OR 13,386, 95% CI 1,541-116,262, p = 0.019). Conclusions: proBNP could be an early marker of severe digestive pathology in PN. Increased proBNP levels could be associated with a significant increased risk of NEC in very immature newborns.
- Published
- 2019
- Full Text
- View/download PDF
23. Sustained Ventricular Tachycardia After Thoracic Traumatism in a Patient With Repaired Tetralogy of Fallot.
- Author
-
Molina Borao I, Urmeneta Ulloa J, Calvo Galiano N, Palanca Arias D, Jiménez Montañés L, and López Ramón M
- Subjects
- Adolescent, Body Surface Potential Mapping, Echocardiography, Heart Ventricles physiopathology, Humans, Male, Tachycardia, Ventricular diagnosis, Tachycardia, Ventricular physiopathology, Tetralogy of Fallot physiopathology, Thoracic Injuries diagnosis, Tachycardia, Ventricular etiology, Tetralogy of Fallot complications, Thoracic Injuries complications
- Published
- 2018
- Full Text
- View/download PDF
24. Use of speckle tracking in the evaluation of late subclinical myocardial damage in survivors of childhood acute leukaemia.
- Author
-
Corella Aznar EG, Ayerza Casas A, Jiménez Montañés L, Calvo Escribano MÁC, Labarta Aizpún JI, and Samper Villagrasa P
- Subjects
- Adolescent, Adult, Anthracyclines adverse effects, Anthracyclines therapeutic use, Antineoplastic Agents adverse effects, Child, Cross-Sectional Studies, Female, Humans, Leukemia complications, Male, Radiation Injuries diagnostic imaging, Radiation Injuries etiology, Radiotherapy adverse effects, Retrospective Studies, Time Factors, Ventricular Dysfunction, Left chemically induced, Ventricular Dysfunction, Left etiology, Ventricular Dysfunction, Left physiopathology, Young Adult, Echocardiography methods, Leukemia drug therapy, Leukemia radiotherapy, Ventricular Dysfunction, Left diagnostic imaging
- Abstract
Heart disease is the leading cause of non-cancer death in childhood cancer survivors. to determine the prevalence of subclinical cardiac dysfunction using speckle tracking and compare its results with those obtained by classical methods of assessing left ventricular function and its relationship with different factors to identify the population at higher risk. Echocardiographic assessment of left ventricular function included ejection fraction, tissue Doppler, longitudinal/circumferential strains and biochemical parameters (troponin-T and Pro-BNP) in a cohort of 57 survivors of childhood acute leukaemia with at least 10 years since diagnosis. Ventricular dysfunction was found in 5.2% of patients in M-mode (ejection fraction-EF < 53% with a reduction in the EF ≥ 10%) and in 7% of patients with Simpson's method, compared with 21.05 and 8.8% with suboptimal global longitudinal strain (GLS) and global circumferential strain, respectively. The GLS alteration was significantly correlated with lower values of left ventricular systolic function and was associated with high tumour risk (odds ratio [OR] 13.8), cumulative doses of anthracyclines ≥ 250 mg/m
2 (OR 7.6) and radiotherapy (OR 7.19). Biomarkers were not useful for the diagnosis of subclinical cardiomyopathy. Good reproducibility was obtained, with an intraobserver correlation of 93.6% and an interobserver correlation of 89.2% in the GLS. The alteration of the GLS was more prevalent than the alteration in the EF and was associated with the treatment received and high tumour risk. strain imaging seems to be a powerful tool to identify an increased number of survivor with an early myocardial injury.- Published
- 2018
- Full Text
- View/download PDF
25. [Complete heart block and asystole in a child with ataxia-telangiectasia].
- Author
-
Palanca Arias D, Ayerza Casas A, Domínguez Cajal M, López Ramón M, and Jiménez Montañés L
- Subjects
- Adolescent, Humans, Male, Ataxia Telangiectasia complications, Heart Arrest etiology, Heart Block etiology
- Abstract
Ataxia-telangiectasia is a disorder characterized by cerebellar ataxia, telangiectasia, immunodeficiency, and increased predisposition to cancer susceptibility. Mutations in the ataxia telangiectasia mutated gene seem to play an important role in normal cell function and in cardiovascular remodeling. We report a case of a 14-year-old boy with ataxia-telangiectasia and high-grade B-non-Hodgkin lymphoma who remained in continuous complete remission after chemotherapy and who was admitted into our Emergency Room presenting with episodes of presyncope. At admission he presented a complete atrioventricular block that evolved into asystole and required placement of a pacemaker. Cumulative cardiotoxic drugs received were at low risk. However, it is possible that this chronic degenerative disease may affect the cardiac conduction system over time. In the reviewed literature there are no or unknown reports of ataxia-telangiectasia with malignant cardiac arrhythmias., (Sociedad Argentina de Pediatría.)
- Published
- 2017
- Full Text
- View/download PDF
26. [Acute pericarditis, complicated by pericardial effusion in a pediatric patient: case report].
- Author
-
Palanca Arias D, Corella Aznar EG, Ayerza Casas A, Fernández Gómez A, López Ramón M, and Jiménez Montañés L
- Subjects
- Acute Disease, Child, Humans, Male, Pericardial Effusion etiology, Pericarditis complications, Postpericardiotomy Syndrome complications
- Abstract
Acute pericarditis is the most common disease of the pericardium encountered in clinical practice. It is diagnosed in 0.1% of all admissions and 5% of emergency room admissions for chest pain. In developed countries, it is usually due to a benign cause. Idiopathic and infectious pericarditis are more common than secondary to surgical pericardiotomy or neoplastic causes, whereas tuberculosis is the dominant cause in developing countries. The most common symptoms of pericarditis are characteristic chest pain and fever. Since pericarditis presents a benign outcome because of self-limiting and good response to conventional anti-inflammatory therapy, it can be safely managed on outpatient basis unless a specific cause is suspected or the patient has high-risk features to avoid complications such as pericardial effusion, cardiac tamponade or recurrent pericarditis. We report a case of pericarditis, diagnosed 9 months after surgical closure of an atrial septal defect, in a 7-year-old boy with favorable evolution., (Sociedad Argentina de Pediatría.)
- Published
- 2017
- Full Text
- View/download PDF
27. [Usefulness of brain natriuretic propeptide in the diagnosis and management of patent ductus arteriosus].
- Author
-
Montaner Ramón A, Galve Pradel Z, Fernández Espuelas C, Jiménez Montañés L, Samper Villagrasa MP, and Rite Gracia S
- Subjects
- Ductus Arteriosus, Patent blood, Ductus Arteriosus, Patent physiopathology, Ductus Arteriosus, Patent therapy, Female, Hemodynamics, Humans, Infant, Newborn, Infant, Premature, Male, Retrospective Studies, Sensitivity and Specificity, Ductus Arteriosus, Patent diagnosis, Natriuretic Peptide, Brain blood, Protein Precursors blood
- Abstract
Introduction: Patent ductus arteriosus (PDA) is a prevalent condition in preterm infants, and may be related to increased morbidity and mortality in the most immature newborns. Recent studies have examined the usefulness of brain natriuretic propeptide (proBNP) in the diagnosis of this pathology. The aim of the study was to evaluate the diagnostic efficacy of proBNP as a marker of hemodynamic overload in PDA., Paients and Methods: A retrospective study was conducted on preterm infants less than 32 weeks of gestation and/or weight less than 1500 grams. Echocardiogram and determination of proBNP levels were performed on all patients. Comparison was made by subgroups according to the presence of PDA and their haemodynamic characteristics., Results: Of the 60 patients enrolled, 71.7% had PDA, of which 86% had haemodynamically significant patent ductus arteriosus (HS-PDA). All of them, but one, received medical treatment with ibuprofen or acetaminophen. Surgical closure was required in 29.7% of HS-PDA. Higher values of proBNP were found in patients with HS-PDA (33338±34494.47pg/mL; p=.000) compared with patients with closed or non-haemodynamically significant ductus arteriosus. Higher values were also found in patients who required surgical closure of PDA (30596.8±14910.9; p=.004). A greater decrease inproBNP levels was found in the group of patients which duct closure after pharmacological treatment (68±24.69% vs -12.22±99.4%; p=.030). ProBNP cutoff-level for HS-PDA was calculated by ROC curve and it was 9321.5pg/mL (Specificity: 100%, Sensitivity: 94.6%)., Conclusions: ProBNP levels are related to the presence or absence of haemodynamically significant patent ductus arteriosus; and its variations with treatment response. High values are also related to the need for surgical closure of PDA., (Copyright © 2015 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2017
- Full Text
- View/download PDF
28. [Cardiovascular involvement in Loeys-Dietz syndrome].
- Author
-
Ayerza Casas A, López Ramón M, Palanca Arias D, and Jiménez Montañés L
- Subjects
- Child, Preschool, Humans, Male, Cardiovascular Diseases etiology, Loeys-Dietz Syndrome complications
- Published
- 2017
- Full Text
- View/download PDF
29. [Spanish consensus on infantile haemangioma].
- Author
-
Baselga Torres E, Bernabéu Wittel J, van Esso Arbolave DL, Febrer Bosch MI, Carrasco Sanz Á, de Lucas Laguna R, Del Pozo Losada J, Hernández Martín Á, Jiménez Montañés L, López Gutiérrez JC, Martín-Santiago A, Redondo Bellón P, Ruíz-Canela Cáceres J, Torrelo Fernández A, Vera Casaño Á, and Vicente Villa MA
- Subjects
- Algorithms, Humans, Infant, Newborn, Practice Guidelines as Topic, Hemangioma diagnosis, Hemangioma therapy, Skin Neoplasms diagnosis, Skin Neoplasms therapy
- Abstract
Introduction: Infantile haemangiomas are benign tumours produced by the proliferation of endothelial cells of blood vessels, with a high incidence in children under the age of one year (4-10%). It is estimated that 12% of them require treatment. This treatment must be administered according to clinical practice guidelines, expert experience, patient characteristics and parent preferences., Methods: The consensus process was performed by using scientific evidence on the diagnosis and treatment of infantile haemangiomas, culled from a systematic review of the literature, together with specialist expert opinions. The recommendations issued were validated by the specialists, who also provided their level of agreement., Results: This document contains recommendations on the classification, associations, complications, diagnosis, treatment, and follow-up of patients with infantile haemangioma. It also includes action algorithms, and addresses multidisciplinary management and referral criteria between the different specialities involved in the clinical management of this type of patient., Conclusions: The recommendations and the diagnostic and therapeutic algorithms of infantile haemangiomas contained in this document are a useful tool for the proper management of these patients., (Copyright © 2015 Asociación Española de Pediatría. Publicado por Elsevier España, S.L.U. All rights reserved.)
- Published
- 2016
- Full Text
- View/download PDF
30. [Not Available].
- Author
-
Corella Aznar EG, Ayerza Casas A, Samper Villagrasa P, Rodríguez Vigil C, Jiménez Montañés L, Calvo Escribano C, and Labarta Aizpun JI
- Subjects
- Adolescent, Cardiovascular Diseases epidemiology, Child, Child, Preschool, Female, Humans, Infant, Insulin Resistance, Leukemia epidemiology, Lost to Follow-Up, Male, Metabolic Diseases epidemiology, Obesity epidemiology, Obesity etiology, Overweight epidemiology, Overweight etiology, Prevalence, Risk Factors, Young Adult, Cardiovascular Diseases etiology, Leukemia complications, Metabolic Diseases etiology, Survivors
- Abstract
Introducción: los supervivientes de leucemia aguda (LA) infantil presentan un riesgo incrementado de alteraciones metabólicas y cardiovasculares que aumentan su morbimortalidad a largo plazo.Objetivo: estimar la prevalencia de obesidad, resistencia a la insulina, dislipemia e hipertensión arterial como factores de riesgo cardiometabólico (FRCM) en un grupo de supervivientes de LA infantil, y analizar las posibles causas asociadas a su desarrollo.Material y métodos: estudio observacional retrospectivo en 47 supervivientes de LA tratados en un periodo de 4 años, que recibieron seguimiento durante 10 años.Resultados: el 40% de los participantes presentaron al menos un FRCM durante el seguimiento, siendo la dislipemia (aumento LDL) el más frecuente (38,3%), seguido de obesidad/sobrepeso (31,9%) y HTA sistólica (23,4%). El sexo femenino se estableció como factor de riesgo parael desarrollo de todos ellos (RR 1,6; RR 3,16; RR 1,69; p < 0,05). Ningún superviviente desarrolló diabetes mellitus, pero sí resistencia a la insulina el 19,4%. Los pacientes con leucemias de peor pronóstico presentaron mayor riesgo de desarrollar obesidad, resistencia a la insulina y aumento de LDL (RR 3,56; RR 4,08; RR 2,53; p < 0,05). Los pacientes tratados con trasplante de progenitores hematopoyéticos presentaron mayor riesgo de obesidad, aumento de LDL e HTA sistólica (RR 2,86; RR 2,39; RR 3,12; p<0,05). La radioterapia se asoció de igual modo con un incremento de resistencia a la insulina e hipertensión arterial sistólica (RR 2,47; RR 2,53; p < 0,05).Conclusiones: existe un aumento en la prevalencia de obesidad/sobrepeso, dislipemia, resistencia a la insulina y alteración de la tensión arterial sistólica en supervivientes de leucemia aguda infantil a lo largo del tiempo, especialmente en aquellos con enfermedades y tratamientos más agresivos.
- Published
- 2016
- Full Text
- View/download PDF
31. Biomarkers detect involvement of acute myocardial injury in a paediatric haemolytic-uraemic syndrome patient.
- Author
-
Palanca Arias D, López Ramón M, and Jiménez Montañés L
- Subjects
- Echocardiography, Electrocardiography, Humans, Infant, Male, Point-of-Care Systems, Biomarkers blood, Cardiomyopathies complications, Hemolytic-Uremic Syndrome diagnostic imaging
- Abstract
Although extrarenal manifestations of haemolytic-uraemic syndrome are not frequent, myocardial dysfunction should be given special consideration because of the importance of proper early haemodynamic management and potential complications. We report the case of a 21-month-old child with haemolytic-uraemic syndrome who developed clinical signs of poor myocardial function with depressed myocardial function noted by bedside echocardiography and significant elevation of biomarkers. Early intervention and supportive treatment for the patient were crucial during the acute phase of cardiac failure, and repeated monitoring of biomarkers and ecocardiography were useful diagnostic tools that provided relevant information throughout the patient's evolution.
- Published
- 2016
- Full Text
- View/download PDF
32. [Right (atrial) appendage enlargement: Prenatal diagnosis and postnatal follow up].
- Author
-
Cardiel Valiente L, Orden Rueda C, Ayerza Casas A, Palanca Arias D, and Jiménez Montañés L
- Subjects
- Dilatation, Pathologic diagnostic imaging, Dilatation, Pathologic drug therapy, Female, Follow-Up Studies, Humans, Infant, Pregnancy, Atrial Appendage diagnostic imaging, Atrial Appendage pathology, Ultrasonography, Prenatal
- Published
- 2016
- Full Text
- View/download PDF
33. [Premature constriction of the ductus arteriosus].
- Author
-
Ayerza Casas A, Jiménez Montañés L, López Ramón M, Lerma Puertas D, and García de la Calzada MD
- Subjects
- Constriction, Pathologic diagnostic imaging, Female, Gestational Age, Humans, Pregnancy, Retrospective Studies, Ductus Arteriosus abnormalities, Ductus Arteriosus diagnostic imaging, Ultrasonography, Prenatal
- Published
- 2015
- Full Text
- View/download PDF
34. [The use of corticosteroids in cryptogenic palsy of the third cranial nerves. A case report].
- Author
-
Jiménez-Montañés L, Martínez-Fernández M, Elizalde-Usechi M, and López-Pisón J
- Subjects
- Child, Preschool, Female, Humans, Ophthalmoplegia diagnosis, Adrenal Cortex Hormones therapeutic use, Oculomotor Nerve physiopathology, Ophthalmoplegia drug therapy, Ophthalmoplegia physiopathology, Prednisone therapeutic use
- Abstract
Introduction: In spite of the rarity of isolated paralysis of the third cranial nerves in infancy, we present an acquired cryptogenic case which had an excellent, rapid response to treatment with corticosteroids started three months after onset of the condition., Clinical Case: A girl aged three and a half years, with no significant past clinical history, presented with a third cranial nerve syndrome of sudden onset, with divergent squint and right ptosis, but no changes in pupil reactivity. All the complementary tests done were normal. After three months of observation, since the condition persisted, treatment was started with oral prednisone 2 mg/kg/day for three months. The ptosis disappeared in two weeks, and two years after treatment was stopped has not reappeared. The absence of pain would suggest that this was not a Tolosa-Hunt syndrome, although pain-free episodes have been described. The absence of alteration in pupil reactions is against, although does not exclude, compression of the third cranial nerve. This finding, together with the spectacular response to corticosteroids would support the diagnosis of inflammation limited to the motor fibres, probably due to a viral infection., Conclusion: We conclude that corticosteroids may be considered in the treatment of cryptogenic cranial neuropathy, once other possible aetiologies have been excluded, with the object of modulation of the theoretical immune mechanisms involved.
- Published
- 1999
35. [Severe toxoplasmosis: two case reports].
- Author
-
Jiménez Hereza JM, Jiménez Montañés L, Rebage Moisés V, Roc Alfaro L, Edo Gimeno MJ, Elizalde Usechi M, Ferrer Novellas C, and Marco Tello A
- Subjects
- Brain pathology, Calcinosis pathology, Female, Humans, Infant, Newborn, Male, Tomography, X-Ray Computed, Toxoplasmosis, Congenital blood
- Published
- 1996
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.