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284 results on '"Kzhyshkowska J"'

2. Master Sintering Curve Constructing Techniques: A Review

Author

Akhatov, I.Sh., primary, Bikmeyev, A.T., additional, Bilyalov, A. R., additional, Chugunov, S. S., additional, Galautdinov, M. F., additional, Kireev, V. N., additional, Kzhyshkowska, J. G., additional, Pavlov, V. N., additional, Pyatnitskaya, S. V., additional, and Yurovskikh, R. S., additional

Published
2023
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5. Changes in blood monocyte functional prof le in breast cancer

Author

Fedorov, A. A., primary, Prostakishina, E. A., additional, Patysheva, M. R., additional, Frolova, A. A., additional, Iamshchikov, P. S., additional, Larionova, I. V., additional, Stakheyeva, M. N., additional, Dorofeeva, M. S., additional, Bragina, O. D., additional, Choynzonov, E. L., additional, Kzhyshkowska, J. G., additional, and Cherdyntseva, N. V., additional

Published
2022
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6. Nuclear Export of Adenovirus RNA

Author

Dobner, T., Kzhyshkowska, J., Compans, R. W., editor, Cooper, M., editor, Ito, Y., editor, Koprowski, H., editor, Melchers, F., editor, Oldstone, M., editor, Olsnes, S., editor, Potter, M., editor, Vogt, P. K., editor, Wagner, H., editor, Hauber, Joachim, editor, and Vogt, Peter K., editor

Published
2001
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17. Makrophagen exprimieren variable Immunrezeptoren und sind bei der Arteriosklerose von Bedeutung

Author

Puellmann, K., primary, Fuchs, T., additional, Kzhyshkowska, J., additional, Gratchev, A., additional, Emmert, A., additional, Fleig, J., additional, Oniga, S., additional, Laird, R., additional, Wessels, J.T., additional, Heida, N.M., additional, Schäfer, K., additional, Becker, H., additional, Ganser, A., additional, Neumaier, M., additional, Kaminski, W.E., additional, and Beham, A.W., additional

Published
2010
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45. Heterogeneous nuclear ribonucleoprotein E1B-AP5 is methylated in its Arg-Gly-Gly (RGG) box and interacts with human arginine methyltransferase HRMT1L1

Author

Kzhyshkowska, J, Schütt, H, Liss, M, Kremmer, E, Stauber, R, Wolf, H, and Dobner, T

Subjects
Cell Nucleus, Protein-Arginine N-Methyltransferases, viruses, Amino Acid Motifs, Intracellular Signaling Peptides and Proteins, Methyltransferases, Cell Biology, biochemical phenomena, metabolism, and nutrition, Methylation, Precipitin Tests, Biochemistry, Heterogeneous-Nuclear Ribonucleoproteins, Cell Line, Protein Structure, Tertiary, src Homology Domains, stomatognathic diseases, Ribonucleoproteins, Two-Hybrid System Techniques, Humans, Fluorescent Antibody Technique, Indirect, neoplasms, Molecular Biology, Research Article, HeLa Cells
Abstract

The heterogeneous nuclear ribonucleoprotein (hnRNP) family includes predominantly nuclear proteins acting at different stages of mRNA metabolism. A characteristic feature of hnRNPs is to undergo post-translational asymmetric arginine methylation catalysed by different type 1 protein arginine methyltransferases (PRMTs). A novel mammalian hnRNP, E1B-AP5, recently identified by its interaction with adenovirus early protein E1B-55kDa, has been proposed to have a regulatory role in adenoviral and host-cell mRNA processing/nuclear export [Gabler, Schutt, Groitl, Wolf, Shenk and Dobner (1998) J. Virol. 72, 7960–7971]. Here we report that E1B-AP5 is methylated in vivo in its Arg-Gly-Gly (RGG)-box domain, known to mediate protein–RNA interactions. The activity responsible for E1B-AP5 methylation forms a complex with E1B-AP5 in vivo. The predominant mammalian arginine methyltransferase HRMT1L2 (hPRMT1) did not detectably methylate endogenous E1B-AP5 despite efficiently methylating a recombinant RGG-box domain of E1B-AP5. Using yeast two-hybrid screening we identified HRMT1L1 (PRMT2) as one of the proteins interacting with E1B-AP5. By in situ immunofluorescence we demonstrated that E1B-AP5 co-localizes with the nuclear fraction of HRMT1L1. The Src homology 3 (SH3) domain of HRMT1L1 was essential for its interaction with E1B-AP5 in vivo. We suggest that HRMT1L1 is responsible for specific E1B-AP5 methylation in vivo.

Published
2001

49. General reportrecommendations in predictive, preventive and personalised medicine 2012: white paper of the European Association for Predictive, Preventive and Personalised Medicine

Author

Golubnitschaja, O, Costigliola, V, Benini, A, Kastrup, J, Berliner, L, Boecker, H, Yeghiazaryan, K, Bowis, J, Bubnov, R, Butler, P, Roelandse, M, Cafiero, C, Chan, W.S.H, Characiejus, D, Coelho, J, Danesi, R, Rovigatti, U, De Meester, F, Desiderio, D.M, Dimitrov, D, Dundar, M, Egorova-Zachernyuk, T, Evans, P, Everaus, H, Ferrari, M, González-Neira, A, Frija, G, Gerner, C, Krapfenbauer, K, Gluud, C, Gozes, I, Marcus-Kalish, M, Grech, G, Greuel, J, Grosios, N, Grossman, I, Hadder, M, Hagan, S, Hewitt, R, Ionescu, J, Iso, H, Kokubo, Y, Jansen, A, Joos, T, Josifova, T, Kapalla, M, Kinkorova, J, Kiper, N, Kovalenko, S, Krestin, G, Krishna, R, Kzhyshkowska, J, Kunin, A, Larionova, V.I, Legg, M, Lemke, H, Lieb, W, Major, T, Mandel, S, Marshall, T, Marzan, M.D, Spiru, L, Mendive, J, Mozaffari, M, Németh, G, Orr, M, Paltsev, M.A, Paul, F, Pinçon-Raymond, M, Pelsers, M, Podbielska, H, Polivka, J, Radojkovic, D, Richter, K, di Sarsina, P.R, Rosolova, H, Rubio, C.A, Safonicheva, O, Suchkov, S, Rukhadze, T, Salminen, L, Scarpa, M, Shabo, A, Shapira, N, Swanton, C, Tasker, R.A, Topolcan, O, Trovato, G.M, Tsangaris, G.T, Vittadini, G, Walkenhorst, J, Yamagishi, K, Yatsuya, H, Zhan, X., and Çocuk Sağlığı ve Hastalıkları

Subjects
integrative medicine, medicine.medical_specialty, MEDLINE, Alternative medicine, preventive and personalised medicine, well-being concept, White paper, Daily practice, Report, Drug Discovery, Health care, medicine, common/rare disease, Product (category theory), predictive, health care economics and organizations, Medical education, education, research, business.industry, Health Policy, Biochemistry (medical), diabetes/cancer/cardiovascular/neurodegenerative diseases, healthcare, ethics, co-morbidities, economy, Integrative medicine, Knowledge deficit, business
Abstract

This report is the collective product of word-leading experts working in the branches of integrative medicine by predictive, preventive and personalised medicine (PPPM) under the coordination of the European Association for Predictive, Preventive and Personalised Medicine. The general report has been prepared as the consortium document proposed at the EPMA World Congress 2011 which took place in Bonn, Germany. This forum analyzed the overall deficits and trends relevant for the top-science and daily practice in PPPM focused on the patient. Follow-up consultations resulted in a package of recommendations for consideration by research units, educators, healthcare industry, policy-makers, and funding bodies to cover the current knowledge deficit in the field and to introduce integrative approaches for advanced diagnostics, targeted prevention, treatments tailored to the person and cost-effective healthcare.

Published
2012

50. P148

Author

Zavyalova, M., primary, Buldakov, M., additional, Krakhmal, N., additional, Telegina, N., additional, Vtorushin, S., additional, Cherdyntseva, N., additional, and Kzhyshkowska, J., additional

Published
2015
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