209 results on '"Kyriakis, John M."'
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2. GCK is essential to systemic inflammation and pattern recognition receptor signaling to JNK and p38.
3. MAP Kinase Pathways
4. Reconstitution of Novel Signalling Cascades Responding to Cellular Stresses [and Discussion]
5. Mixed-Lineage Kinase 3 Regulates B-Raf through Maintenance of the B-Raf/Raf-1 Complex and Inhibition by the NF2 Tumor Suppressor Protein
6. Mxi2, a Mitogen-Activated Protein Kinase that Recognizes and Phosphorylates Max Protein
7. Enzymatic Characteristics of the c-Raf-1 Protein Kinase
8. Insulin Stimulates Choline Acetyltransferase Activity in Cultured Embryonic Chicken Retina Neurons
9. MAP Kinase Pathways
10. Glycogen Synthase Kinase-3β Inhibition Ameliorates Cardiac Parasympathetic Dysfunction in Type 1 Diabetic Akita Mice
11. Phosphorylation of threonine 276 in Smad4 is involved in transforming growth factor-[beta]-induced nuclear accumulation
12. Contributors
13. Insulin and Growth Factor Signaling Pathways
14. Activation of SAPK/JNKs In Vitro
15. Defective Rac-mediated proliferation and survival after targeted mutation of the [[beta].sub.1] integrin cytodomain
16. Protein kinase cascades activated by stress and inflammatory cytokines
17. Requirement for ceramide-initiated SAPK/JNK signalling in stress-induced apoptosis
18. 3. Making the connection: coupling of stress-activated ERK/MAPK (extracellular-signal-regulated kinase/mitogen-activated protein kinase) core signalling modules to extracellular stimuli and biological responses
19. Activation of the SAPK pathway by the human STE20 homologue germinal centre kinase
20. Role of SAPK/ERK kinase-1 in the stress-activated pathway regulating transcription factor c-Jun
21. Raf meets Ras: completing the framework of a signal transduction pathway
22. The stress-activated protein kinase subfamily of c-Jun kinases
23. Normal and oncogenic p21ras proteins bind to the amino-terminal regulatory domain of c-Raf-1
24. Signal transduction: Life-or-death decisions
25. Raf-1 activates MAP kinase-kinase
26. Phosphorylation of c-jun mediated by MAP kinases
27. Role of the Stress-activated Protein Kinases in Endothelin-induced Cardiomyocyte Hypertrophy
28. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
29. The Role of HAP Kinases in Breast Cancer.
30. Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
31. Chapter 4 - Insulin and Growth Factor Signaling Pathways
32. Activation of SAPKs/JNKs and p38s In Vitro
33. In the Beginning, There Was Protein Phosphorylation
34. Mammalian MAPK Signal Transduction Pathways Activated by Stress and Inflammation: A 10-Year Update
35. Decreased metalloprotease 9 induction, cardiac fibrosis, and higher autophagy after pressure overload in mice lacking the transcriptional regulator p8
36. Deficiency of transcriptional regulator p8 induces autophagy and causes impaired cardiac function
37. Mammalian Ste20-like Kinase (Mst2) Indirectly Supports Raf-1/ERK Pathway Activity via Maintenance of Protein Phosphatase-2A Catalytic Subunit Levels and Consequent Suppression of Inhibitory Raf-1 Phosphorylation
38. Deficiency of the Transcriptional Regulator p8 Results in Increased Autophagy and Apoptosis, and Causes Impaired Heart Function
39. Thinking Outside the Box about Ras
40. The integration of signaling by multiprotein complexes containing Raf kinases
41. Dissection of a Signaling Pathway by Which Pathogen-associated Molecular Patterns Recruit the JNK and p38 MAPKs and Trigger Cytokine Release
42. Helix-Loop-Helix Protein p8, a Transcriptional Regulator Required for Cardiomyocyte Hypertrophy and Cardiac Fibroblast Matrix Metalloprotease Induction
43. Changes in Insulin Binding to Developing Embryonic Chick Neural Retina Cells
44. Gene 33/RALT Is Induced by Hypoxia in Cardiomyocytes, Where It Promotes Cell Death by Suppressing Phosphatidylinositol 3-Kinase and Extracellular Signal-Regulated Kinase Survival Signaling
45. Gene 33 Is an Endogenous Inhibitor of Epidermal Growth Factor (EGF) Receptor Signaling and Mediates Dexamethasone-induced Suppression of EGF Function
46. A Novel Role for Mixed Lineage Kinase 3 (MLK3) in B-Raf Activation and Cell proliferation
47. Germinal Center Kinase Is Required for Optimal Jun N-Terminal Kinase Activation by Toll-Like Receptor Agonists and Is Regulated by the Ubiquitin Proteasome System and Agonist-Induced, TRAF6-Dependent Stabilization
48. MLK3 is required for mitogen activation of B-Raf, ERK and cell proliferation
49. The Pro-hypertrophic Basic Helix-Loop-Helix Protein p8 Is Degraded by the Ubiquitin/Proteasome System in a Protein Kinase B/Akt- and Glycogen Synthase Kinase-3-dependent Manner, whereas Endothelin Induction of p8 mRNA and Renal Mesangial Cell Hypertrophy Require NFAT4
50. Inhibitors of Protein Kinase Signaling Pathways
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