29 results on '"Kyouichi Kaneko"'
Search Results
2. Impact of depression on masked hypertension and variability in home blood pressure in treated hypertensive patients
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Makoto Shoji, Kyouichi Kaneko, Shinji Koba, Norikazu Watanabe, Tsutomu Toshida, Youichi Kobayashi, Eiichi Geshi, Hiroto Fukuoka, Taiju Matsui, and Hiroyuki Kayano
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Male ,medicine.medical_specialty ,Physiology ,Blood Pressure ,White coat hypertension ,Prehypertension ,Japan ,Masked Hypertension ,Sleep Initiation and Maintenance Disorders ,Internal medicine ,Prevalence ,Internal Medicine ,medicine ,Humans ,Prospective Studies ,Prospective cohort study ,Depression (differential diagnoses) ,Aged ,Morning ,Aged, 80 and over ,Depression ,business.industry ,Blood Pressure Determination ,Middle Aged ,Center for Epidemiologic Studies Depression Scale ,medicine.disease ,Blood pressure ,Endocrinology ,Hypertension ,Female ,Cardiology and Cardiovascular Medicine ,business - Abstract
This study was conducted to determine the effects of depression and/or insomnia on masked hypertension (MHT) compared with other types of HT and on variability in home-measured blood pressure (HBP) and clinic BP (CBP). Three hundred and twenty-eight hypertensives (132 women) aged 68±10 years were classified into four BP types: controlled HT (CHT), white-coat HT, MHT and sustained HT (SHT), based on CBP (140/90 mm Hg) and morning HBP (135/85 mm Hg) measurements. A score of ⩾16 on the Center for Epidemiologic Studies Depression Scale (CES-D) was defined as depression. The mean values and s.d. of BP were calculated from measurements taken during the 14 consecutive days just before the CES-D evaluation. Compared with the CHT group, the risk of depression was 2.77-fold higher in the SHT group and even higher in the MHT group (7.02-fold). The association between depression and MHT was augmented in the presence of insomnia and was somewhat stronger in women. A HBP variability index defined as s.d./mean BPs in both morning and night time was significantly higher in MHT than in the other BP types, whereas that of CBP was not. Both morning and night-time HBP variability were significantly higher in depressive patients than in non-depressives. These suggest that depression is associated with MHT and that increases both morning and night-time HBP variability but not CBP variability. Physicians should be mindful of mental stresses such as depression in their hypertensive patients when forming strategies to control BP over the diurnal cycle.
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- 2015
3. Clinical Significance of Reverse Redistribution Phenomenon for 201Tl Scintigraphy in Nonischemic Disease
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Akira Shinozuka, Yasushi Akutsu, Hiroto Sasamori, Takehiko Gokan, M. Kato, Osamu Miyagami, Jumpei Suyama, Akifumi Niiya, Kyouichi Kaneko, and Norifumi Hosaka
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medicine.medical_specialty ,Reverse redistribution ,medicine.diagnostic_test ,business.industry ,Internal medicine ,medicine ,Cardiology ,Clinical significance ,Disease ,Radiology ,Scintigraphy ,business - Published
- 2014
4. PROGNOSIS OF DRUG-COATING BALLOON ANGIOPLASTY FOR TREATMENT OF IN-STENT RESTENOSIS AFTER PERCUTANEOUS CORONARY INTERVENTION TO CORONARY ARTERY CALCIUM LESION
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Yusuke Kodama, Kosuke Nomura, Kyouichi Kaneko, Teruo Sekimoto, Yasushi Akutsu, Hiroaki Tsujita, Toshiro Shinke, and Hiroki Tanisawa
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medicine.medical_specialty ,business.industry ,medicine.medical_treatment ,Percutaneous coronary intervention ,Balloon ,Lesion ,Coronary artery calcium ,Internal medicine ,Angioplasty ,Cardiology ,medicine ,Drug coating ,In stent restenosis ,medicine.symptom ,Cardiology and Cardiovascular Medicine ,business - Published
- 2019
5. Five-year follow-up of a giant coronary aneurysm using virtual coronary angioscopy
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Takehiko Sambe, Jumpei Suyama, Katsuji Oguchi, Kazuo Itabashi, Yusuke Kodama, Kyouichi Kaneko, Naoki Uchida, Junya Iwasaki, Takehiko Gokan, Toshikazu Kurihara, Hui-Ling Li, Yuji Hamazaki, Shinichi Kobayashi, Yasushi Akutsu, and Youichi Kobayashi
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Atherectomy, Coronary ,Male ,medicine.medical_specialty ,Time Factors ,Adolescent ,Coronary angioscopy ,medicine.medical_treatment ,MEDLINE ,Mucocutaneous Lymph Node Syndrome ,Coronary Angiography ,Atherectomy ,Young Adult ,Aneurysm ,Predictive Value of Tests ,Multidetector Computed Tomography ,Multidetector computed tomography ,Humans ,Medicine ,Child ,Vascular Calcification ,business.industry ,Coronary Aneurysm ,Coronary Stenosis ,Five year follow up ,General Medicine ,Angioscopy ,medicine.disease ,Treatment Outcome ,Predictive value of tests ,Radiographic Image Interpretation, Computer-Assisted ,Tomography ,Radiology ,Cardiology and Cardiovascular Medicine ,business ,Tomography, Optical Coherence - Published
- 2014
6. Reversible T-Wave Inversions and Neurogenic Myocardial Stunning in a Patient with Recurrent Stress-Induced Cardiomyopathy
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Akira Shinozuka, Tsutomu Toshida, Jumpei Suyama, Yusuke Kodama, Youichi Kobayashi, Hiroyuki Kayano, Kyouichi Kaneko, Yasushi Akutsu, Hui-Ling Li, and Takehiko Gokan
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Myocardial stunning ,medicine.medical_specialty ,Apical ballooning ,business.industry ,Cardiomyopathy ,General Medicine ,Coronary stenosis ,medicine.disease ,SEVERE DYSFUNCTION ,Physiology (medical) ,Anesthesia ,T wave ,Internal medicine ,Mental stress ,Cardiology ,Medicine ,Stress induced cardiomyopathy ,Cardiology and Cardiovascular Medicine ,business - Abstract
A 72-year-old female was diagnosed as a stress-induced cardiomyopathy from apical ballooning pattern of left ventricular dysfunction without coronary artery stenosis after the mental stress. ECG showed the transient T-wave inversions after the ST-segment elevations. By the mental stress after 1 year, she showed a transient dysfunction with similar ECG changes again. T-wave inversions recovered earlier, and cardiac sympathetic dysfunction showed a lighter response corresponding to the less severe dysfunction than those after the first onset. Wellens' ECG pattern was associated with the degree of neurogenic myocardial stunning with sympathetic hyperinnervation caused by mental stress.
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- 2013
7. Abstract 13968: Regional Calcified Plaque Score evaluated by Computed Tomographic Angiography for Indicating the Addition of Rotational Atherectomy in Patients With Percutaneous Coronary Intervention
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Teruo Sekimoto, Yasushi Akutsu, Yuji Hamazaki, Hiroaki Tsujita, Shigeto Tsukamoto, Kyouichi Kaneko, Yusuke Kodama, and Youichi Kobayashi
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Physiology (medical) ,cardiovascular diseases ,Cardiology and Cardiovascular Medicine - Abstract
Introduction: Rotational atherectomy (Rota) has been proposed as the best strategy relative to all other percutaneous coronary interventions (PCI) in complex and severely calcified lesions, and the examination of calcified plaque conditions is necessary to determine whether Rota is indicated. Multidetector computed tomography coronary angiography (CTA) can provide non-invasive assessment of calcified plaques with obstructive coronary artery disease. Hypothesis: We hypothesized that regional coronary artery calcium score (CAC) of the target lesion on CTA would aid in deciding whether subsequent intervention strategies should be pursued, including Rota. Methods: Lesion CAC and calcified plaque patterns measured in the target lesion on CTA were evaluated regionally with quantitative coronary analysis (QCA) on angiography for predicting Rota treatment in 116 consecutive patients (168 target lesions) who had undergone their first PCI (mean age ± standard deviations: 68 ± 10 years, females: 19.8%). Results: PCI without Rota was performed successfully in 105 patients (154 lesions), and Rota treatment was added in 11 patients (14 lesions). The patients with Rota had significantly higher SYNTAX score (p=0.007) and CAC than those without Rota (p Conclusions: The lesion CAC as a simple marker of calcified plaque condition in target lesion is useful for indicating the addition of Rota in patients with PCI.
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- 2015
8. Association Between Left and Right Atrial Remodeling With Atrial Fibrillation Recurrence After Pulmonary Vein Catheter Ablation in Patients With Paroxysmal Atrial Fibrillation
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Yusuke Kodama, Kaoru Tanno, Hui-Ling Li, Kyouichi Kaneko, Yasushi Akutsu, Yuji Hamazaki, Takehiko Gokan, Jumpei Suyama, and Youichi Kobayashi
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Male ,Tachycardia ,medicine.medical_specialty ,medicine.medical_treatment ,Pilot Projects ,Catheter ablation ,Atrial Function, Right ,Pulmonary vein ,Heart Conduction System ,Recurrence ,Internal medicine ,Atrial Fibrillation ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Heart Atria ,Tachycardia, Paroxysmal ,medicine.diagnostic_test ,business.industry ,Atrial fibrillation ,Odds ratio ,Middle Aged ,medicine.disease ,Confidence interval ,Pulmonary Veins ,Ambulatory ,Catheter Ablation ,Electrocardiography, Ambulatory ,Cardiology ,Atrial Function, Left ,Female ,medicine.symptom ,Tomography, X-Ray Computed ,Cardiology and Cardiovascular Medicine ,business ,Electrocardiography ,Follow-Up Studies - Abstract
Background— Left atrial (LA) remodeling is a factor in atrial fibrillation (AF) recurrence after pulmonary vein catheter ablation (CA), but right atrium (RA) remodeling has not been investigated for possible associations to AF recurrence. Methods and Results— Using 64-slice multidetector computed tomography, RA and LA volumes were measured 3-dimensionally before CA in 65 patients with initially proven idiopathic paroxysmal AF (mean age, 60±10 years, 81.5% men). The CA procedure was guided by CARTO Merge atrial electroanatomic mapping. Sixteen patients (24.6%) had AF recurrence within the 6-month period after the CA. The recurrence was associated with a large RA volume [odds ratio, 1.04; 95% confidence interval (CI), 1.02 to 1.07, P P =0.002], and low LA mean voltage with 1.03 [95% CI, 1.01 to 1.05, P =0.002]. After adjustment for potential confounding variables, RA and LA volumes remained predictive of AF recurrence. Large atrial volumes (mL) (RA ≥87 or LA ≥99) predicted AF recurrence (sensitivity of RA volume: 81.3% in 13 of 16 patients with AF recurrence; specificity: 75.5% in 37 of 49 patients without AF recurrence; sensitivity of LA volume: 81.3% in 13 of 16 patients with AF recurrence; specificity: 69.4% in 34 of 49 patients without AF recurrence), and the combined estimate of both atrial volumes was incremental and additive prognostic power (sensitivity: 75% in 12 of 16 patients with AF recurrence; specificity: 93.9% in 46 of 49 patients without AF recurrence). Conclusions— Both LA and RA remodeling are equally associated with post-CA AF recurrence.
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- 2011
9. Iodine-123 mIBG Imaging for Predicting the Development of Atrial Fibrillation
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Hui-Ling Li, Kyouichi Kaneko, Kaoru Tanno, Yasushi Akutsu, Youichi Kobayashi, Yusuke Kodama, Takehiko Gokan, Yuji Hamazaki, Akira Shinozuka, and Jumpei Suyama
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Male ,medicine.medical_specialty ,Sympathetic nervous system ,animal structures ,heart failure ,3-Iodobenzylguanidine ,Scintigraphy ,Electrocardiography ,Internal medicine ,Iodine-123 ,medicine ,Humans ,scintigraphy ,atrial fibrillation ,Radiology, Nuclear Medicine and imaging ,Radionuclide Imaging ,Aged ,sympathetic nervous system ,Ejection fraction ,medicine.diagnostic_test ,business.industry ,Heart ,Atrial fibrillation ,medicine.disease ,medicine.anatomical_structure ,Radiology Nuclear Medicine and imaging ,Heart failure ,Cardiology ,Female ,Radiopharmaceuticals ,Cardiology and Cardiovascular Medicine ,business - Abstract
ObjectivesWe investigated whether cardiac sympathetic nervous system (SNS) activity measured by iodine-123 meta-iodobenzylguanidine (123I-mIBG) imaging would be associated with both the occurrence of heart failure (HF) and the transit to permanent atrial fibrillation (AF) in patients with paroxysmal AF.BackgroundAtrial fibrillation occurs suddenly and transiently and can persist, and results in the occurrence of HF. An important feature of AF and HF is their propensity to coexist not only because they share antecedent risk factors, but also because the one may directly predispose the heart to the other. However, a useful modality for predicting the occurrences of both those has not been established in patients with paroxysmal AF.MethodsThe 123I-mIBG scintigraphy was performed to evaluate cardiac SNS activity presented as the heart/mediastinum ratio in 98 consecutive patients (age 66 ± 13 years, 63.3% male) with idiopathic paroxysmal AF and preserved left ventricular ejection fraction (≥50%).ResultsDuring 4 ± 3.6 years of follow-up, the transit to permanent AF was associated with the occurrence of HF (34.3% in 12 of 35 patients with permanent AF vs. 6.3% in 4 of 63 patients without, p < 0.0001). Lower heart/mediastinum ratio and lower left ventricular ejection fraction were the independent predictors of the transit to permanent AF with adjusted hazard ratios of 3.44 (95% confidence interval [CI]: 1.9 to 6.2, p < 0.0001) and 1.04 (95% CI: 1.01 to 1.08, p = 0.014). Further, these factors and higher plasma brain natriuretic peptide concentration were the independent predictors of the occurrence of HF with permanent AF, with adjusted hazard ratios of 5.08 (95% CI: 1.5 to 17.5, p = 0.011), 1.11 (95% CI: 1.03 to 1.19, p = 0.004), and 1.004 (95% CI: 1.001 to 1.008, p = 0.014).ConclusionsCardiac SNS abnormality was associated with the occurrence of both HF and permanent AF in paroxysmal AF patients, and 123I-mIBG imaging may be a useful modality for predicting the development of AF.
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- 2011
10. Right Atrial Volume Calculated by Multi-detector Computed Tomography: Useful Predictor of Atrial Fibrillation Recurrence after Pulmonary Vein Catheter Ablation
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Yasushi Akutsu, Taku Asano, Kyouichi Kaneko, Hui-Ling Li, Youichi Kobayashi, Takehiko Gokan, Takashi Hashizume, Yusuke Kodama, Jumpei Suyama, Kaoru Tanno, and Mitsuharu Kawamura
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medicine.medical_specialty ,business.industry ,Multi detector computed tomography ,medicine.medical_treatment ,Atrial fibrillation ,Catheter ablation ,medicine.disease ,Right atrial ,Pulmonary vein ,Internal medicine ,medicine ,Cardiology ,Tomography ,Radiology ,Iohexol ,business ,Volume (compression) ,medicine.drug - Published
- 2010
11. Significance of cardiac sympathetic nervous system abnormality for predicting vascular events in patients with idiopathic paroxysmal atrial fibrillation
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Yusuke Kodama, Youichi Kobayashi, Kyouichi Kaneko, Kaoru Tanno, Jumpei Suyama, Yasushi Akutsu, Takehiko Gokan, Mitsuharu Kawamura, Taku Asano, Hui-Ling Li, Yuji Hamazaki, and Akira Shinozuka
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Male ,Risk ,medicine.medical_specialty ,Sympathetic Nervous System ,animal structures ,Heart disease ,Myocardial Infarction ,Kaplan-Meier Estimate ,Disease-Free Survival ,Iodine Radioisotopes ,Japan ,Internal medicine ,Atrial Fibrillation ,Humans ,Medicine ,Radiology, Nuclear Medicine and imaging ,Prospective Studies ,Myocardial infarction ,Stroke ,Aged ,Aged, 80 and over ,Heart Failure ,biology ,business.industry ,C-reactive protein ,Hazard ratio ,Atrial fibrillation ,General Medicine ,Middle Aged ,Prognosis ,medicine.disease ,3-Iodobenzylguanidine ,C-Reactive Protein ,Heart failure ,Cardiology ,biology.protein ,Female ,Radiopharmaceuticals ,Abnormality ,business ,Follow-Up Studies - Abstract
Neuronal system activity plays an important role for the prognosis of patients with atrial fibrillation (AF). Using (123)I metaiodobenzylguanidine ((123)I-MIBG) scintigraphy, we investigated whether a cardiac sympathetic nervous system (SNS) abnormality would be associated with an increased risk of vascular events in patients with paroxysmal AF.(123)I-MIBG scintigraphy was performed in 69 consecutive patients (67 + or - 13 years, 62% men) with paroxysmal AF who did not have structural heart disease. SNS integrity was assessed from the heart to mediastinum (H/M) ratio on delayed imaging. Serum concentration of C-reactive protein (CRP) was measured before (123)I-MIBG study.During a mean of 4.5 + or - 3.6 years follow-up, 19 patients had myocardial infarction, stroke or heart failure (range: 0.2-11.5 years). SNS abnormality (H/M ratio2.7) and high CRP (or = 0.3 mg/dl) were associated with the vascular events (58.3% in 14 of 24 patients with SNS abnormality vs 11.1% in 5 of 45 patients without SNS abnormality, p0.0001, 52.4% in 11 of 21 patients with high CRP vs 16.7% in 8 of 48 patients without high CRP, p0.0001). After adjustment for potential confounding variables such as age, left atrial dimension and left ventricular function, SNS abnormality was an independent predictor of vascular events with a hazard ratio of 4.1 [95% confidence interval (CI): 1.3-12.6, p = 0.014]. Further, SNS abnormality had an incremental and additive prognostic power in combination with high CRP with an adjusted hazard ratio of 4.1 (95% CI: 1.5-10.9, p = 0.006).SNS abnormality is predictive of vascular events in patients with idiopathic paroxysmal AF.
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- 2009
12. Cardiac Cine MRI at 3.0 Tesla: Comparison of Image Quality between SSFP and FLASH Sequence
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Yusuke Kodama, Takehiko Gokan, Makoto Saiki, Jumpei Suyama, Kyouichi Kaneko, Yasushi Akutsu, Yoshimitsu Ohgiya, Noritaka Seino, and Masanori Hirose
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Flash (photography) ,Nuclear magnetic resonance ,Image quality ,business.industry ,Medicine ,Steady-state free precession imaging ,business ,Sequence (medicine) ,Cine mri - Published
- 2009
13. Cardiac sympathetic nerve abnormality predicts ventricular tachyarrhythmic events in patients without conventional risk of sudden death
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Taku Asano, Yusuke Kodama, Mitsuharu Kawamura, Kyouichi Kaneko, Akira Shinozuka, Hui-Ling Li, Youichi Kobayashi, Yasushi Akutsu, Kaoru Tanno, and Takehiko Gokan
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Adult ,Male ,Risk ,medicine.medical_specialty ,Sympathetic Nervous System ,Time Factors ,Heart disease ,Scintigraphy ,Ventricular tachycardia ,Sudden death ,Sudden cardiac death ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Radionuclide Imaging ,medicine.diagnostic_test ,business.industry ,Hazard ratio ,Confounding ,Heart ,General Medicine ,Prognosis ,medicine.disease ,3-Iodobenzylguanidine ,Death, Sudden, Cardiac ,Tachycardia, Ventricular ,cardiovascular system ,Cardiology ,Female ,Abnormality ,business - Abstract
Patients with structural heart disease, severe left ventricular dysfunction, or history of cardiac arrest are at increased risk of sudden cardiac death. However, a useful marker for predicting sudden cardiac death is not clarified in low-risk patients without those conventional risks. We hypothesized that cardiac sympathetic nerve system (SNS) abnormality would be associated with ventricular tachyarrhythmic events in low-risk patients with ventricular tachycardia (VT).Iodine-123 metaiodobenzylguanidine ((123)I-MIBG) scintigraphy was performed in 50 patients (mean+/-standard deviation, age 54 +/- 16 years, 52% males) with VT who did not have structural heart disease, severe left ventricular dysfunction, or history of cardiac arrest, and SNS activity was assessed from heart/mediastinal (H/M) ratio on delayed images.Over 11 years of follow-up, three patients had sudden deaths (6%) and nine patients had sustained ventricular tachyarrhythmic events (18%). SNS abnormality, defined as H/M ratio2.8, was predictive of sudden death or ventricular tachyarrhythmic events (45% in nine of 20 patients with SNS abnormality vs 16.7% in three of 30 patients without SNS abnormality, p = 0.005). After adjustment for potential confounding variables including slight left ventricular dysfunction, SNS abnormality remained independently predictive of ventricular tachyarrhythmic events with a hazard ratio of 5.3 (95% confidence interval = 1.4 to 20.8, p = 0.016).SNS abnormality is a readily available and powerful predictor of recurrent ventricular tachyarrhythmic events in patients with VT who did not have conventional risk of sudden cardiac death. (123)I-MIBG scintigraphy can provide prognostic information of VT patients without conventional risk.
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- 2008
14. Thallium-201 and I-123 Beta-Methyl Iodophenyl-Pentadecanoic Acid Dual Isotope Single Photon Emission Computed Tomography for Evaluating Reperfusion Injury After Successful Reperfusion Therapy
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Jumpei Suyama, Kyouichi Kaneko, Yasushi Akutsu, Hideyuki Yamanaka, Hideki Nishimura, Yuji Hamazaki, Youichi Kobayashi, Akira Shinozuka, Hui-Ling Li, Yusuke Kodama, and Takehiko Gokan
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Male ,Acute coronary syndrome ,Atherectomy ,Time Factors ,Myocardial Ischemia ,chemistry.chemical_element ,Coronary Artery Disease ,Single-photon emission computed tomography ,Iodine Radioisotopes ,Coronary artery disease ,Reperfusion therapy ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,Aged ,Tomography, Emission-Computed, Single-Photon ,medicine.diagnostic_test ,Iodobenzenes ,business.industry ,Fatty Acids ,General Medicine ,medicine.disease ,Thallium Radioisotopes ,Treatment Outcome ,chemistry ,Echocardiography ,Reperfusion Injury ,No reflow phenomenon ,Exercise Test ,cardiovascular system ,Thallium ,business ,Nuclear medicine ,Reperfusion injury ,Perfusion - Abstract
We report a reperfusion injury after rotational coronary atherectomy (RA) in a 66-year-old man with coronary artery disease. Submaximal exercise with thallium-201 single photon emission computed tomography (SPECT) imaging before reperfusion showed partially reversible perfusion defects in the apex and reversible perfusion defects in the anteroseptal area. Thallium-201 and I-123 beta-methyl iodophenyl-pentadecanoic acid (BMIPP) dual isotope SPECT was performed 5 days before and 1 hour after RA, and 1 month after RA. SPECT images at 1 hour after recovery of no reflow phenomenon after RA revealed enlargement of the defect sizes on thallium-201 and BMIPP uptakes in the anteroseptal area including the apex compared with those before RA. The defect size of thallium-201 uptake was progressively improved on 5 hour delayed redistribution imaging and 1 month after reperfusion compared with that of BMIPP uptake. In conclusion, the changes for the worse of thallium-201 uptake and fatty acid metabolism immediately after the no reflow phenomenon may indicate an injured membrane integrity with altered myocardial metabolism rather than myocardial ischemia. Thallium-201 and I-123 BMIPP dual isotope SPECT is useful for evaluating reperfusion injury after successful reperfusion therapy in a patient with acute coronary syndrome.
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- 2009
15. Impact of Continuous Positive Airway Pressure on Left Ventricular Systolic and Diastolic Function in Treated Hypertensives with Sleep Apnea Syndrome
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Youichi Kobayashi, Kyouichi Kaneko, Taiju Matsui, Shinji Koba, Hiroyuki Kayano, Makoto Shouji, Tsutomu Toshida, Hiroto Fukuoka, and Norikazu Watanabe
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medicine.medical_specialty ,business.industry ,Internal medicine ,medicine.medical_treatment ,Cardiology ,Medicine ,Sleep apnea ,Diastolic function ,Continuous positive airway pressure ,Cardiology and Cardiovascular Medicine ,business ,medicine.disease - Published
- 2015
16. Reversible T-wave inversions and neurogenic myocardial stunning in a patient with recurrent stress-induced cardiomyopathy
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Yasushi, Akutsu, Kyouichi, Kaneko, Yusuke, Kodama, Hui-Ling, Li, Jumpei, Suyama, Tsutomu, Toshida, Hiroyuki, Kayano, Akira, Shinozuka, Takehiko, Gokan, and Youichi, Kobayashi
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Myocardial Stunning ,Case Reports ,Electrophysiology ,Iodine Radioisotopes ,Life Change Events ,3-Iodobenzylguanidine ,Electrocardiography ,Recurrence ,Takotsubo Cardiomyopathy ,Earthquakes ,Humans ,Female ,Radiopharmaceuticals ,Radionuclide Imaging ,Stress, Psychological ,Aged - Abstract
A 72‐year‐old female was diagnosed as a stress‐induced cardiomyopathy from apical ballooning pattern of left ventricular dysfunction without coronary artery stenosis after the mental stress. ECG showed the transient T‐wave inversions after the ST‐segment elevations. By the mental stress after 1 year, she showed a transient dysfunction with similar ECG changes again. T‐wave inversions recovered earlier, and cardiac sympathetic dysfunction showed a lighter response corresponding to the less severe dysfunction than those after the first onset. Wellens’ ECG pattern was associated with the degree of neurogenic myocardial stunning with sympathetic hyperinnervation caused by mental stress.
- Published
- 2013
17. A combination of P wave electrocardiography and plasma brain natriuretic peptide level for predicting the progression to persistent atrial fibrillation: comparisons of sympathetic activity and left atrial size
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Kyouichi Kaneko, Kaoru Tanno, Yusuke Kodama, Yasushi Akutsu, Jumpei Suyama, Takehiko Gokan, Youichi Kobayashi, Atsuo Namiki, Hui-Ling Li, Fumito Miyoshi, Taku Asano, and Norikazu Watanabe
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Male ,medicine.medical_specialty ,Risk Assessment ,Sensitivity and Specificity ,Disease-Free Survival ,Electrocardiography ,Japan ,Left atrial ,Physiology (medical) ,Internal medicine ,Atrial Fibrillation ,Natriuretic Peptide, Brain ,medicine ,Prevalence ,Humans ,cardiovascular diseases ,Heart Atria ,Aged ,Brain natriuretic peptide level ,medicine.diagnostic_test ,business.industry ,Incidence ,P wave ,Reproducibility of Results ,Sympathetic activity ,Atrial fibrillation ,Stroke Volume ,Organ Size ,Middle Aged ,medicine.disease ,Brain natriuretic peptide ,Endocrinology ,Echocardiography ,Persistent atrial fibrillation ,Chronic Disease ,Cardiology ,Disease Progression ,Female ,Cardiology and Cardiovascular Medicine ,business ,Biomarkers ,Follow-Up Studies - Abstract
Development of atrial fibrillation (AF) is complexly associated with electrical and structural remodeling and other factors every stage of AF development. We hypothesized that P wave electrocardiography with an elevated brain natriuretic peptide (BNP) level would be associated with the progression to persistence from paroxysmal AF.P wave electrocardiography such as a maximum P wave duration (MPWD) and dispersion by 12-leads ECG, heart/mediastinum (H/M) ratio by delayed iodine-123 metaiodobenzylguanidine scintigraphic imaging, left ventricular ejection fraction (LVEF), and left atrial dimension (LAD) by echocardiography, and plasma BNP level were measured to evaluate the electrical and structural properties and sympathetic activity in 71 patients (mean ± standard deviation, age: 67 ± 13 years, 63.4 % males) with idiopathic paroxysmal AF.Over a 12.9-year follow-up period, AF developed into persistent AF in 30 patients. A wider MPWD (129 ms) (p = 0.001), wider P wave dispersion (60 ms) (p = 0.001), LAD enlargement (40 mm) (p = 0.001), higher BNP level (72 pg/mL) (p = 0.002), lower H/M ratio (≤2.7) (p = 0.025), and lower LVEF (≤60 %) (p = 0.035) were associated with the progression to persistent AF, and the wide MPWD was an independently powerful predictor of the progression to persistent AF with a hazard ratio (HR) of 5.49 [95 % confidence interval (CI) 2.38-12.7, p 0.0001] after adjusting for potential confounding variables, such as age and sex. The combination of wide MPWD and elevated BNP level was additive and incremental prognostic power with 13.3 [2.16-13, p 0.0001].The wide MPWD with elevated BNP level was associated with the progression to persistent AF.
- Published
- 2013
18. CARDIAC SYMPATHETIC NERVOUS SYSTEM ABNORMALITY PREDICTS THE INCREASED RISK IN PATIENTS WITH WOLFF-PARKINSON-WHITE SYNDROME
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Kyouichi Kaneko, Kaoru Tanno, Youichi Kobayashi, Jumpei Suyama, Takehiko Gokan, Hui-Ling Li, Yasushi Akutsu, and Yusuke Kodama
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Sympathetic nervous system ,Increased risk ,medicine.anatomical_structure ,White (horse) ,business.industry ,Anesthesia ,medicine ,In patient ,Abnormality ,business ,Cardiology and Cardiovascular Medicine - Published
- 2011
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19. Images in cardiovascular medicine. Pulmonary vein obstruction after catheter ablation following atrial fibrillation
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Yasushi, Akutsu, Kyouichi, Kaneko, Yusuke, Kodama, Hui-Ling, Li, Jumpei, Suyama, Akira, Shinozuka, Takehiko, Gokan, Yuji, Hamazaki, Kaoru, Tanno, and Youichi, Kobayashi
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Male ,Treatment Outcome ,Pulmonary Veins ,Regional Blood Flow ,Atrial Fibrillation ,Angiography ,Catheter Ablation ,Humans ,Stents ,Tomography, Spiral Computed ,Aged - Published
- 2011
20. Pulmonary Vein Obstruction After Catheter Ablation Following Atrial Fibrillation
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Yasushi Akutsu, Akira Shinozuka, Jumpei Suyama, Yuji Hamazaki, Kyouichi Kaneko, Yusuke Kodama, Hui-Ling Li, Takehiko Gokan, Kaoru Tanno, and Youichi Kobayashi
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medicine.medical_specialty ,Paroxysmal atrial fibrillation ,business.industry ,medicine.medical_treatment ,Atrial fibrillation ,Catheter ablation ,Ablation ,medicine.disease ,Pulmonary Vein Obstruction ,Catheter ,Embolism ,Physiology (medical) ,Internal medicine ,Multidetector computed tomography ,cardiovascular system ,medicine ,Cardiology ,cardiovascular diseases ,Radiology ,Cardiology and Cardiovascular Medicine ,business - Abstract
The patient was 68-year-old man with highly symptomatic paroxysmal atrial fibrillation. Transoesophageal echocardiography was performed to confirm no left atrial embolism, and contrast-enhanced 64-row multidetector computed tomography (MDCT) was performed to clarify the anatomic forms and routes of pulmonary veins (PV) before ablation (Figure 1A). The circumferential ablation procedure was performed using electroanatomical mapping (Figure 1B). Radiofrequency catheter energy was delivered with a closed irrigation cool-tip ablation catheter. The patient was kept on oral anticoagulation with a controlled international normalized ratio between 2 and …
- Published
- 2011
21. Sympathetic dysfunction of systemic right ventricle in congenitally corrected transposition of the great arteries
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Yusuke Kodama, Youichi Kobayashi, Hui-Ling Li, Yasushi Akutsu, Jumpei Suyama, Kyouichi Kaneko, and Takehiko Gokan
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Male ,medicine.medical_specialty ,Sympathetic nervous system ,Sympathetic Nervous System ,Coronary Vessel Anomalies ,Heart Ventricles ,Transposition of Great Vessels ,Adrenergic beta-Antagonists ,Cardiomyopathy ,Coronary Angiography ,Heart Conduction System ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Diuretics ,Cardiac imaging ,Heart Failure ,Tomography, Emission-Computed, Single-Photon ,business.industry ,medicine.disease ,medicine.anatomical_structure ,Congenitally corrected transposition ,Ventricle ,Great arteries ,Echocardiography ,Heart failure ,Cardiology ,Cardiology and Cardiovascular Medicine ,business ,Tomography, X-Ray Computed ,Perfusion - Abstract
We evaluate the systemic right ventricle (SRV) failure of congenitally corrected transposition of the great arteries using the scintigraphic studies in a case with 32-year-old male who improved the heart failure by the use of beta-adrenergic blockers. The myocardial perfusion sympathetic nervous system activity mismatch with preserved coronary flow and wall thickness indicates a distinctive feature as SRV cardiomyopathy, suggesting the importance of recovery of SRV sympathetic dysfunction for improving the prognosis.
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- 2009
22. The significance of cardiac sympathetic nervous system abnormality in the long-term prognosis of patients with a history of ventricular tachyarrhythmia
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Hui-Ling Li, Yusuke Kodama, Kyouichi Kaneko, Taku Asano, Mitsuharu Kawamura, Kaoru Tanno, Akira Shinozuka, Yasushi Akutsu, Takehiko Gokan, and Youichi Kobayashi
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Male ,medicine.medical_specialty ,animal structures ,Time Factors ,Heart disease ,Ventricular tachycardia ,Sudden cardiac death ,Recurrence ,Internal medicine ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Survival rate ,Fibrillation ,Analysis of Variance ,Ejection fraction ,business.industry ,Hazard ratio ,Heart ,Middle Aged ,medicine.disease ,Prognosis ,Survival Rate ,Autonomic Nervous System Diseases ,Cardiology ,Tachycardia, Ventricular ,Female ,medicine.symptom ,Abnormality ,business ,Follow-Up Studies - Abstract
UNLABELLED Severe left ventricular dysfunction or cardiac sympathetic nervous system (SNS) abnormality predicts cardiac death in various heart diseases, including arrhythmogenic disorders. However, it is not clear whether SNS abnormality predicts sudden cardiac death during long-term follow-up in patients with a history of ventricular tachyarrhythmia. We hypothesized that SNS abnormality would be associated with recurrent ventricular arrhythmic events. METHODS 123I-metaiodobenzylguanidine (MIBG) scintigraphy was performed on 86 patients (mean age+/-SD, 46+/-19 y, 65.1% men) with a history of ventricular tachycardia or fibrillation. 123I-MIBG (111 MBq) was intravenously administered under resting conditions, and planar images were obtained 15 min and 4 h later (anterior view for 6 min; 512x512 matrices; zoom ratio, 1.0). SNS activity was assessed using the heart-to-mediastinum ratio on delayed imaging. RESULTS During about 11 y of follow-up (mean+/-SD, 5.2+/-3.7 y), 3 patients (3.5%) had sudden cardiac death and 21 patients (24.4%) had sustained ventricular tachyarrhythmic events. SNS abnormality, defined as a heart-to-mediastinum ratio of less than 2.8, and left ventricular dysfunction, defined as a left ventricular ejection fraction of less than 50%, were associated with sudden cardiac death or recurrent ventricular tachyarrhythmic events (18/40 patients [45%] with SNS abnormality, vs. 6/46 patients [13%] without, P=0.004; 9/15 patients [60%] with left ventricular dysfunction, vs. 15/71 patients [21.1%] without, P=0.008). After adjustment for potential confounding variables such as age, sex, coronary risk factors, medication use, history of structural heart disease, and left ventricular function, SNS abnormality was a powerful predictor of recurrent arrhythmic events, with a hazard ratio of 3.6 [95% confidence interval, 1.4-9.2, P=0.007]). Further, SNS abnormality had incremental and additive prognostic power in combination with left ventricular dysfunction, with an adjusted hazard ratio of 4.4 [95% confidence interval, 1.9-9.9, P
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- 2008
23. Electrocardiographic change after recanalization in a patient with recent extensive anterior wall myocardial infarction
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Youichi Kobayashi, Yusuke Kodama, Yasushi Akutsu, Hui-Ling Li, Yuji Hamazaki, Kyouichi Kaneko, Jyumpei Suyama, Hideki Nishimura, Akira Shinozuka, and Takehiko Gokan
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Male ,medicine.medical_specialty ,medicine.medical_treatment ,Ischemia ,Myocardial Infarction ,Myocardial Reperfusion ,Single-photon emission computed tomography ,Anterior Descending Coronary Artery ,Electrocardiographic Change ,Electrocardiography ,Internal medicine ,Occlusion ,medicine ,Humans ,Embolization ,Aged ,medicine.diagnostic_test ,business.industry ,medicine.disease ,medicine.anatomical_structure ,Treatment Outcome ,Coronal plane ,Cardiology ,Radiology ,Cardiology and Cardiovascular Medicine ,business ,Artery - Abstract
In a 66-year-old male with subacute extensive anterior wall myocardial infarction, we report a change in ST vector orientation from a basal anterior to a mid anterior after coronary artery recanalization of the proximal left anterior descending coronary artery with rotational atherectomy. The ST vector shift on the frontal plane after recanalization was consistent with a change toward more distal location of the ischemia on thallium-201 single photon emission computed tomography images compared to the findings during an exercise test before intervention. These findings may be correlated with local occlusion caused by distal microvascular embolization which was not visualized on coronary angiography following recanalization.
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- 2008
24. Abstract 726: Cardiac Sympathetic Nerve System Abnormality Predicts Long-Term Outcome in Patients with Paroxysmal Atrial Fibrillation who did not have Conventional Risk Factors
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Yasushi Akutsu, Kyouichi Kaneko, Yusuke Kodama, Hui-Ling Li, Jumpei Suyama, Akira Shinozuka, Takehiko Gokan, and Youichi Kobayashi
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Physiology (medical) ,Cardiology and Cardiovascular Medicine - Abstract
Backgrounds: A history of structural heart disease, heart failure, or stroke increases mortality in patients with atrial fibrillation (AF). However, a useful marker for predicting mortality is not clarified in AF patients without those conventional risks. We recently reported cardiac sympathetic nerve system (SNS) abnormality as a predictor of arrhythmogenic mortality. We hypothesized that SNS abnormality would be associated with increased mortality in patients with paroxysmal AF who didn’t have conventional risk factors. Methods and Results: Iodine-123 metaiodobenzylguanidine scintigraphy was performed to measure Heart/Mediastinum (H/M) ratio as SNS activity in 48 patients (mean ± standard deviation, age: 65 ± 14 years, 65% males) with paroxysmal AF who didn’t have structural heart disease, heart failure, or stroke. P wave dispersion on 12-lead ECG and left atrial dimension on echocardiography were also measured to evaluate structural and electrical properties. Over 11 years follow up, 15 patients (31.3%) transited to permanent AF, and 12 (25%) had cardio/cerebrovascular events. SNS abnormality (defines as H/M ratio Conclusion: SNS abnormality is predictive of mortality in patients with paroxysmal AF who did not have conventional risk.
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- 2008
25. Technetium-99m pyrophosphate/thallium-201 dual-isotope SPECT imaging predicts reperfusion injury in patients with acute myocardial infarction after reperfusion
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Yuji Hamazaki, Hideki Nishimura, Takehiko Gokan, Youichi Kobayashi, Kyouichi Kaneko, Jumpei Suyama, Hui-Ling Li, Yasushi Akutsu, Yusuke Kodama, and Akira Shinozuka
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Tomography, Emission-Computed, Single-Photon ,medicine.medical_specialty ,Technetium Tc 99m Pyrophosphate ,medicine.diagnostic_test ,business.industry ,Myocardial Infarction ,Myocardial Reperfusion Injury ,General Medicine ,Recovery of Function ,medicine.disease ,Thallium Radioisotopes ,Reperfusion therapy ,Spect imaging ,Internal medicine ,Cardiology ,medicine ,ST segment ,Humans ,Radiology, Nuclear Medicine and imaging ,Myocardial infarction ,business ,Perfusion ,Technetium-99m ,Reperfusion injury ,Emission computed tomography - Abstract
Microcirculatory failure after reperfusion is clinically indicated to cause reperfusion injury whereas excessive intracellular calcium ion overload is experimentally proved as a key mechanism of reperfusion injury. We hypothesized that technetium-99m ((99m)Tc) pyrophosphate (Tc-PYP) uptake in injured but viable infarct-related myocardium with preserved myocardial perfusion after reperfusion estimated by thallium-201 ((201)Tl) uptake would be associated with final functional recovery.Dual-isotope Tc-PYP/(201)Tl single-photon emission computed tomography (SPECT) was performed 2 days after successful reperfusion therapy in patients with first acute myocardial infarction, and 50 patients (63 +/- 13 years old, female 22%) with preserved (201)Tl uptakes ofor = 50% in reperfused myocardium was followed for 1 month. Tc-PYP uptake was assessed as the heart-to-sternum (H/S) ratio. Two-dimensional echocardiography was also performed 2 days and 1 month after reperfusion to evaluate functional recovery.High Tc-PYP uptake, defined as the H/S ratioor = 0.81, was predictive of chronic phase no functional recovery (73.7% in 14 of 19 patients with high uptake vs 16.1% in five of 31 patients without those, p0.0001). After adjustment for potential confounding variables, including electrocardiographic persistent ST segment elevation at 1 h after reperfusion, high Tc-PYP uptake remained independently predictive of no functional recovery with odds ratio of 8.7 (95% confidential interval = 2 to 38.7; p = 0.005).High Tc-PYP uptake in reperfused but viable infarct-related myocardium was a powerful predictor of no functional recovery, which may reflect excessive intracellular calcium ion overload caused by reperfusion injury. Tc-PYP/(201)Tl dual-isotope SPECT imaging can provide prognostic information after reperfusion.
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- 2008
26. Stratified three-dimensional fusion imaging of delayed-enhancement magnetic resonance and multi-detector computed tomography to identify a ventricular tachycardia focus
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Norikazu Watanabe, Jumpei Suyama, Hui-Ling Li, Yusuke Kodama, Kyouichi Kaneko, Kaoru Tanno, Taku Asano, Yasushi Akutsu, Youichi Kobayashi, Takehiko Gokan, and Yuji Hamazaki
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Male ,medicine.medical_specialty ,Action Potentials ,Delayed enhancement ,Ventricular tachycardia ,Multimodal Imaging ,Imaging, Three-Dimensional ,Text mining ,Heart Conduction System ,Predictive Value of Tests ,Internal medicine ,Image Interpretation, Computer-Assisted ,Multidetector Computed Tomography ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Angioplasty, Balloon, Coronary ,Anterior Wall Myocardial Infarction ,Cardiac imaging ,Image fusion ,medicine.diagnostic_test ,business.industry ,Multi detector computed tomography ,Magnetic resonance imaging ,Middle Aged ,medicine.disease ,Magnetic Resonance Imaging ,Tachycardia, Ventricular ,Cardiology ,Radiology ,Cardiology and Cardiovascular Medicine ,business ,Focus (optics) - Published
- 2013
27. Multidetector Computed Tomography in an Adult Patient with Silent Patent Ductus Arteriosus
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Yasushi Akutsu, Yusuke Kodama, Youichi Kobayashi, Kyouichi Kaneko, Takehiko Gokan, and Noritaka Seino
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medicine.medical_specialty ,medicine.anatomical_structure ,business.industry ,Ductus arteriosus ,Multidetector computed tomography ,Medicine ,General Medicine ,Radiology ,Cardiology and Cardiovascular Medicine ,business - Published
- 2009
28. Usefulness of Severe Cardiac Sympathetic Dysfunction to Predict the Occurrence of Rapid Atrial Fibrillation in Patients With Wolff-Parkinson-White Syndrome.
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Yasushi Akutsu, Kyouichi Kaneko, Yusuke Kodama, Hui-Ling Li, Taku Asano, Jumpei Suyama, Kaoru Tanno, Atsuo Namiki, Akira Shinozuka, Takehiko Gokan, and Youichi Kobayashi
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ATRIAL fibrillation , *ADRENERGIC mechanisms , *WOLFF-Parkinson-White syndrome , *RADIONUCLIDE imaging , *ELECTROPHYSIOLOGY , *CONTROL groups , *PATIENTS - Abstract
Atrial fibrillation (AF) can be a potentially life-threatening arrhythmia when it conducts rapidly through the accessory pathway, which was not predicted by the noninvasive method. We evaluated the cardiac sympathetic activity for predicting the occurrence of AF in patients with Wolff-Parkinson-White (WPW) syndrome. Iodine-123 metaiodobenzylguanidine scintigraphy was performed under stable sinus rhythm conditions at rest <1 week before an electrophysiologic study (EPS) to assess the sympathetic activity using the heart/mediastinum (H/M) ratio in 45 consecutive patients with WPW who had a history of supraventricular tachycardia (mean ± SD, age: 47 ± 17 years, 42.2% women). The study also included 15 normal healthy volunteers (56 ± 17 years, 40% women). The H/M ratio was lower in patients with WPW syndrome than in the normal control group, and in the 15 patients with AF induced during EPS than in the 30 patients without AF (p <0.0001). The sensitivity of H/M ratio ≤2.8 for predicting the AF induced during EPS was 75% in 12 of 16 patients, and the specificity was 89.7% in 26 of 29 patients. The H/M ratio was positively correlated with anterograde effective refractory period (r = 0.514, p <0.0001). The sensitivity of H/M ratio ≤2.75 for predicting the AF with a short anterograde effective refractory period (≤250 ms) was 91.7% in 11 of 12 patients, and the specificity was 90.9% in 30 of 33 patients. In conclusion, the severe cardiac sympathetic dysfunction was associated with the occurrence of AF, particularly in those with rapid AF and in patients with WPW syndrome. [ABSTRACT FROM AUTHOR]
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- 2013
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29. Dataset of calcified plaque condition in the stenotic coronary artery lesion obtained using multidetector computed tomography to indicate the addition of rotational atherectomy during percutaneous coronary intervention
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Teruo Sekimoto, Yasushi Akutsu, Koshiro Sakai, Katsuji Oguchi, Masayuki Sakurai, Hiroaki Tsujita, Ryota Kosaki, Yuji Hamazaki, Hiroyuki Yokota, Yusuke Kodama, Shigeto Tsukamoto, Jumpei Suyama, Kyouichi Kaneko, Takehiko Gokan, Shinichi Kobayashi, Hui-Ling Li, Atsushi Aoki, Youichi Kobayashi, Takehiko Sambe, and Naoki Uchida
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Target lesion ,medicine.medical_specialty ,medicine.medical_treatment ,030204 cardiovascular system & hematology ,Rotational atherectomy ,lcsh:Computer applications to medicine. Medical informatics ,030218 nuclear medicine & medical imaging ,Percutaneous coronary intervention ,Lesion ,Multidetector computed tomography ,03 medical and health sciences ,0302 clinical medicine ,medicine ,cardiovascular diseases ,lcsh:Science (General) ,Data Article ,Multidisciplinary ,business.industry ,musculoskeletal, neural, and ocular physiology ,nutritional and metabolic diseases ,Coronary artery calcium scores ,CT angiography ,Conventional PCI ,Ecg gating ,cardiovascular system ,lcsh:R858-859.7 ,Radiology ,medicine.symptom ,business ,lcsh:Q1-390 ,Stenotic coronary artery - Abstract
Our data shows the regional coronary artery calcium scores (lesion CAC) on multidetector computed tomography (MDCT) and the cross-section imaging on MDCT angiography (CTA) in the target lesion of the patients with stable angina pectoris who were scheduled for percutaneous coronary intervention (PCI). CAC and CTA data were measured using a 128-slice scanner (Somatom Definition AS+; Siemens Medical Solutions, Forchheim, Germany) before PCI. CAC was measured in a non-contrast-enhanced scan and was quantified using the Calcium Score module of SYNAPSE VINCENT software (Fujifilm Co. Tokyo, Japan) and expressed in Agatston units. CTA were then continued with a contrast-enhanced ECG gating to measure the severity of the calcified plaque condition. We present that both CAC and CTA data are used as a benchmark to consider the addition of rotational atherectomy during PCI to severely calcified plaque lesions. Keywords: Coronary artery calcium scores, Multidetector computed tomography, CT angiography, Rotational atherectomy, Percutaneous coronary intervention
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