Search

Your search keyword '"Kyomi Kalter"' showing total 1 results
Start Over Author "Kyomi Kalter"
1 results on '"Kyomi Kalter"'

1. Solid phase chemistry approach to the SAR development of a novel class of active site-directed thrombin inhibitors

Author

Jan E. Gillespie, Robert J. Foglesong, Catherine C. Redick, Donetta S. Gifford-Moore, Gerald F. Smith, Daniel Jon Sall, Michael P. Lynch, Mary George Johnson, Jefferson Ray Mccowan, Kyomi Kalter, and Duane D. Bronson

Subjects
Future studies, biology, Chemistry, Organic Chemistry, Amine functionalization, Active site, Benzothiophene, Biochemistry, Combinatorial chemistry, chemistry.chemical_compound, Phase (matter), Drug Discovery, biology.protein, Molecule, Discovery and development of direct thrombin inhibitors
Abstract

A solid phase chemistry approach utilizing Mitsunobu chemistry, amine functionalization, and parallel purification was used to produce a diverse library of benzothiophene analogs. These analogs were used to advance the SAR of this class of molecules and give new directions for future studies.

Published
1999
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results