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1. Tracheal intubation in critically ill adults with a physiologically difficult airway. An international Delphi study

Author

Karamchandani, Kunal, Nasa, Prashant, Jarzebowski, Mary, Brewster, David J., De Jong, Audrey, Bauer, Philippe R., Berkow, Lauren, Brown, III, Calvin A., Cabrini, Luca, Casey, Jonathan, Cook, Tim, Divatia, Jigeeshu Vasishtha, Duggan, Laura V., Ellard, Louise, Ergan, Begum, Jonsson Fagerlund, Malin, Gatward, Jonathan, Greif, Robert, Higgs, Andy, Jaber, Samir, Janz, David, Joffe, Aaron M., Jung, Boris, Kovacs, George, Kwizera, Arthur, Laffey, John G., Lascarrou, Jean-Baptiste, Law, J. Adam, Marshall, Stuart, McGrath, Brendan A., Mosier, Jarrod M., Perin, Daniel, Roca, Oriol, Rollé, Amélie, Russotto, Vincenzo, Sakles, John C., Shrestha, Gentle S., Smischney, Nathan J., Sorbello, Massimiliano, Tung, Avery, Jabaley, Craig S., and Myatra, Sheila Nainan

Published
2024
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3. ESICM guidelines on acute respiratory distress syndrome: definition, phenotyping and respiratory support strategies

Author

Grasselli, Giacomo, Calfee, Carolyn S., Camporota, Luigi, Poole, Daniele, Amato, Marcelo B. P., Antonelli, Massimo, Arabi, Yaseen M., Baroncelli, Francesca, Beitler, Jeremy R., Bellani, Giacomo, Bellingan, Geoff, Blackwood, Bronagh, Bos, Lieuwe D. J., Brochard, Laurent, Brodie, Daniel, Burns, Karen E. A., Combes, Alain, D’Arrigo, Sonia, De Backer, Daniel, Demoule, Alexandre, Einav, Sharon, Fan, Eddy, Ferguson, Niall D., Frat, Jean-Pierre, Gattinoni, Luciano, Guérin, Claude, Herridge, Margaret S., Hodgson, Carol, Hough, Catherine L., Jaber, Samir, Juffermans, Nicole P., Karagiannidis, Christian, Kesecioglu, Jozef, Kwizera, Arthur, Laffey, John G., Mancebo, Jordi, Matthay, Michael A., McAuley, Daniel F., Mercat, Alain, Meyer, Nuala J., Moss, Marc, Munshi, Laveena, Myatra, Sheila N., Ng Gong, Michelle, Papazian, Laurent, Patel, Bhakti K., Pellegrini, Mariangela, Perner, Anders, Pesenti, Antonio, Piquilloud, Lise, Qiu, Haibo, Ranieri, Marco V., Riviello, Elisabeth, Slutsky, Arthur S., Stapleton, Renee D., Summers, Charlotte, Thompson, Taylor B., Valente Barbas, Carmen S., Villar, Jesús, Ware, Lorraine B., Weiss, Björn, Zampieri, Fernando G., Azoulay, Elie, and Cecconi, Maurizio

Published
2023
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4. Respiratory Support Techniques for COVID-19-Related ARDS in a Sub-Saharan African Country: A Multicenter Observational Study

Author

Kwizera, Arthur, Kabatooro, Daphne, Atumanya, Patience, Tumukunde, Janat, Kalungi, Joyce, Mwanje, Arthur Kavuma, Obua, Daniel, Agaba, Peter, Sendagire, Cornelius, Nakibuuka, Jane, Owachi, Darius, Dünser, Martin W., Alenyo-Ngabirano, Anne, Olaro, Charles, Kyobe-Bosa, Henry, Kirenga, Bruce J., Nakiyingi, Lydia, Kiwanuka, Noah, Kateete, David Patrick, Joloba, Moses, Sewankambo, Nelson, and Summers, Charlotte

Published
2023
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6. Feasibility of the modified sequential organ function assessment score in a resource-constrained setting: a prospective observational study

Author

Sendagire, Cornelius, Lipnick, Michael S, Kizito, Sam, Kruisselbrink, Rebecca, Obua, Daniel, Ejoku, Joseph, Ssemogerere, Lameck, Nakibuuka, Jane, and Kwizera, Arthur

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Clinical Research, Good Health and Well Being, Adult, Critical Illness, Developing Countries, Feasibility Studies, Female, Humans, Intensive Care Units, Male, Mortality, Organ Dysfunction Scores, Prospective Studies, Uganda, Young Adult, Modified sequential organ function assessment, Low and middle-income countries, Illness severity scoring system, Critical care, Medical Physiology, Anesthesiology, Clinical sciences
Abstract

BackgroundSub-Saharan Africa has a great burden of critical illness with limited health care resources. We evaluated the feasibility and utility of the modified Sequential Organ Function Assessment (mSOFA) score in assessing morbidity and mortality in the National Referral Hospital's intensive care unit (ICU) for one year.MethodsWe conducted a prospective, observational cohort study on patients above 12 years of age admitted to the ICU at Mulago Hospital (Kampala, Uganda). All SOFA scores were determined at admission and at 48 h. We modified the SOFA score by replacing the PaO2/FiO2 ratio with SPO2/FiO2. The primary outcome was ICU mortality.ResultsThis ICU cohort of 118 patients had a mean age of 37 years and an ICU mortality rate of 46.6%. Non-survivors had higher initial (7.7 SD 3.8 vs. 5.5 SD 3.3; p = 0.007), mean (8.1 SD 3.9 vs 4.7 SD 2.6; p

Published
2017

8. A living WHO guideline on drugs for covid-19

Author

Siemieniuk, Reed, Rochwerg, Bram, Agoritsas, Thomas, Lamontagne, François, Leo, Yee-Sin, Macdonald, Helen, Agarwal, Arnav, Zeng, Linan, Lytvyn, Lyubov, Appiah, John Adabie, Amin, Wagdy, Arabi, Yaseen, Blumberg, Lucille, Burhan, Erlina, Bausch, Frederique Jacquerioz, Calfee, Carolyn S, Cao, Bin, Cecconi, Maurizio, Chanda, Duncan, Cooke, Graham, Du, Bin, Dunning, Jake, Geduld, Heike, Gee, Patrick, Hashimi, Madiha, Hui, David S, Kabra, Sushil, Kanda, Seema, Kawano-Dourado, Leticia, Kim, Yae-Jean, Kissoon, Niranjan, Kwizera, Arthur, Laake, Jon Henrik, Machado, Flavia R, Mahaka, Imelda, Manai, Hela, Mino, Greta, Nsutebu, Emmanuel, Pshenichnaya, Natalia, Qadir, Nida, Sabzwari, Saniya, Sarin, Rohit, Sharland, Michael, Shen, Yinzhong, Ranganathan, Shalini Sri, Souza, Joao, Ugarte, Sebastian, Venkatapuram, Sridhar, Dat, Vu Quoc, Vuyiseka, Dubula, Stegemann, Miriam, Wijewickrama, Ananda, Maguire, Brittany, Zeraatkar, Dena, Bartoszko, Jessica, Ge, Long, Brignardello-Petersen, Romina, Owen, Andrew, Guyatt, Gordon, Diaz, Janet, Jacobs, Michael, and Vandvik, Per Olav

Published
2020

9. Remdesivir for severe covid-19 : a clinical practice guideline

Author

Rochwerg, Bram, Agarwal, Arnav, Zeng, Linan, Leo, Yee-Sin, Appiah, John Adabie, Agoritsas, Thomas, Bartoszko, Jessica, Brignardello-Petersen, Romina, Ergan, Begum, Ge, Long, Geduld, Heike, Gershengorn, Hayley B, Manai, Hela, Huang, Minhua, Lamontagne, François, Kanda, Seema, Kawano-Dourado, Leticia, Kurian, Linda, Kwizera, Arthur, Murthy, Srinivas, Qadir, Nida, Siemieniuk, Reed, Silvestre, Maria Asuncion, Vandvik, Per Olav, Ye, Zhikang, Zeraatkar, Dena, and Guyatt, Gordon

Published
2020

10. Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021

Author

Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flávia R., Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Wiersinga, W. Joost, Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Coz Yataco, Angel, De Waele, Jan, Dellinger, R. Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa, Ferrer, Ricard, Gomersall, Charles, Hodgson, Carol, Møller, Morten Hylander, Iwashyna, Theodore, Jacob, Shevin, Kleinpell, Ruth, Klompas, Michael, Koh, Younsuck, Kumar, Anand, Kwizera, Arthur, Lobo, Suzana, Masur, Henry, McGloughlin, Steven, Mehta, Sangeeta, Mehta, Yatin, Mer, Mervyn, Nunnally, Mark, Oczkowski, Simon, Osborn, Tiffany, Papathanassoglou, Elizabeth, Perner, Anders, Puskarich, Michael, Roberts, Jason, Schweickert, William, Seckel, Maureen, Sevransky, Jonathan, Sprung, Charles L., Welte, Tobias, Zimmerman, Janice, and Levy, Mitchell

Published
2021
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14. Recognition of Sepsis in Resource-Limited Settings

Author

Kwizera, Arthur, Adhikari, Neill K. J., Angus, Derek C., Dondorp, Arjen M., Dünser, Martin W., Festic, Emir, Haniffa, Rashan, Kissoon, Niranjan, Martin-Loeches, Ignacio, Lundeg, Ganbold, Dondorp, Arjen M., editor, Dünser, Martin W., editor, and Schultz, Marcus J., editor

Published
2019
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15. Current Challenges in the Management of Sepsis in ICUs in Resource-Poor Settings and Suggestions for the Future

Author

Schultz, Marcus J., Dünser, Martin W., Dondorp, Arjen M., Adhikari, Neill K. J., Iyer, Shivakumar, Kwizera, Arthur, Lubell, Yoel, Papali, Alfred, Pisani, Luigi, Riviello, Elisabeth D., Angus, Derek C., Azevedo, Luciano C., Baker, Timothy, Diaz, Janet V., Festic, Emir, Haniffa, Rashan, Jawa, Randeep, Jacob, Shevin T., Kissoon, Niranjan, Lodha, Rakesh, Martin-Loeches, Ignacio, Lundeg, Ganbold, Misango, David, Mer, Mervyn, Mohanty, Sanjib, Murthy, Srinivas, Musa, Ndidiamaka, Nakibuuka, Jane, Neto, Ary Serpa, Mai, NT Hoang, Thien, Binh Nguyen, Pattnaik, Rajyabardhan, Phua, Jason, Preller, Jacobus, Povoa, Pedro, Ranjit, Suchitra, Talmor, Daniel, Thevanayagam, Jonarthan, Thwaites, C. Louise, Dondorp, Arjen M., editor, Dünser, Martin W., editor, and Schultz, Marcus J., editor

Published
2019
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17. Safety and efficacy of hydroxychloroquine for treatment of non-severe COVID-19 among adults in Uganda: a randomized open label phase II clinical trial

Author

Byakika-Kibwika, Pauline, Sekaggya-Wiltshire, Christine, Semakula, Jerome Roy, Nakibuuka, Jane, Musaazi, Joseph, Kayima, James, Sendagire, Cornelius, Meya, David, Kirenga, Bruce, Nanzigu, Sarah, Kwizera, Arthur, Nakwagala, Fred, Kisuule, Ivan, Wayengera, Misaki, Mwebesa, Henry G., Kamya, Moses R., and Bazeyo, William

Published
2021
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19. Executive Summary: Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021

Author

Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flávia R., Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Joost Wiersinga, W., Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Yataco, Angel Coz, De Waele, Jan, Dellinger, R. Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa, Ferrer, Ricard, Gomersall, Charles, Hodgson, Carol, Møller, Morten Hylander, Iwashyna, Theodore, Jacob, Shevin, Kleinpell, Ruth, Klompas, Michael, Koh, Younsuck, Kumar, Anand, Kwizera, Arthur, Lobo, Suzana, Masur, Henry, McGloughlin, Steven, Mehta, Sangeeta, Mehta, Yatin, Mer, Mervyn, Nunnally, Mark, Oczkowski, Simon, Osborn, Tiffany, Papathanassoglou, Elizabeth, Perner, Anders, Puskarich, Michael, Roberts, Jason, Schweickert, William, Seckel, Maureen, Sevransky, Jonathan, Sprung, Charles L., Welte, Tobias, Zimmerman, Janice, and Levy, Mitchell

Published
2021
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21. The Impact of Trauma System Implementation on Patient Quality of Life and Economic Burden: A Systematic Review Study Protocol

Author

Bath, Michael F, Kohler, Katharina, Hobbs, Laura, Kuhn, Isla, Nabulyato, William M, Kwizera, Arthur, Walker, Laura E, Wilkins, Tom, Stubbs, Daniel, Halimah, Sara, Burnstein, Rowan, Kolias, Angelos G, Hutchinson, Peter, Clarkson, John, Bashford, Tom, Bath, Michael F [0000-0003-1879-1093], Bashford, Tom [0000-0003-0228-9779], and Apollo - University of Cambridge Repository

Subjects
Quality of Life, Surgery, Trauma Systems, Morbidity, Economic Burden
Abstract

BACKGROUND: Trauma accounts for 10% of global mortality, with increasing rates disproportionally affecting low- and middle-income countries. In an attempt to improve clinical outcomes after injury, trauma systems have been implemented in multiple countries over recent years. However, whilst many studies have subsequently demonstrated improvements in overall mortality outcomes, less is known about the impact trauma systems have on morbidity, quality of life, and economic burden. This systematic review seeks to assess the existing evidence base for trauma systems with these outcome measures. METHODS: This review will include any study that assesses the impact implementation of a trauma system has on patient morbidity, quality of life, or economic burden. Any comparator study, including cohort, case-control, and randomised controlled studies, will be included, both retrospective or prospective in nature. Studies conducted from any region in the world and involving any age of patient will be included. We will collect data on any morbidity outcomes, health-related quality of life measures, or health economic assessments reported. We predict a high heterogeneity in these outcomes used and will therefore keep inclusion criteria broad. DISCUSSION: Previous reviews have shown the significant improvements that can be achieved in mortality outcomes with the implementation of an organised trauma system, however the wider impact they can have on morbidity outcomes, quality of life measures, and the economic burden of trauma, is less well described. This systematic review will present all available data on these outcomes, helping to better characterise both the societal and economic impact of trauma system implementation. HIGHLIGHTS: Trauma systems are known to improve mortality rates, however less in known on the impact they have on morbidity outcomes, quality of life, and economic burdenWe aim to perform a systematic review to identify any comparator study that assesses the impact implementation of a trauma system on these outcomesUnderstanding the impact trauma systems can have on wider parameters, such as economic and quality of life outcomes, is crucial to allow governments globally to appropriately allocate often limited healthcare resources.PROSPERO registration number: CRD42022348529.

Published
2023

23. Increasing evidence-based interventions in patients with acute infections in a resource-limited setting: a before-and-after feasibility trial in Gitwe, Rwanda

Author

Urayeneza, Olivier, Mujyarugamba, Pierre, Rukemba, Zacharie, Nyiringabo, Vincent, Ntihinyurwa, Polyphile, Baelani, John I., Kwizera, Arthur, Bagenda, Danstan, Mer, Mervyn, Musa, Ndidiamaka, Hoffman, Julia T., Mudgapalli, Ashok, Porter, Austin M., Kissoon, Niranjan, Ulmer, Hanno, Harmon, Lori A., Farmer, Joseph C., Dünser, Martin W., Patterson, Andrew J., and for the Sepsis in Resource-Limited Nations Workgroup of the Surviving Sepsis Campaign

Published
2018
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25. ESICM guidelines on acute respiratory distress syndrome:definition, phenotyping and respiratory support strategies

Author

Grasselli, Giacomo, Calfee, Carolyn S., Camporota, Luigi, Poole, Daniele, Amato, Marcelo B.P., Antonelli, Massimo, Arabi, Yaseen M., Baroncelli, Francesca, Beitler, Jeremy R., Bellani, Giacomo, Bellingan, Geoff, Blackwood, Bronagh, Bos, Lieuwe D.J., Brochard, Laurent, Brodie, Daniel, Burns, Karen E.A., Combes, Alain, D’Arrigo, Sonia, De Backer, Daniel, Demoule, Alexandre, Einav, Sharon, Fan, Eddy, Ferguson, Niall D., Frat, Jean Pierre, Gattinoni, Luciano, Guérin, Claude, Herridge, Margaret S., Hodgson, Carol, Hough, Catherine L., Jaber, Samir, Juffermans, Nicole P., Karagiannidis, Christian, Kesecioglu, Jozef, Kwizera, Arthur, Laffey, John G., Mancebo, Jordi, Matthay, Michael A., McAuley, Daniel F., Mercat, Alain, Meyer, Nuala J., Moss, Marc, Munshi, Laveena, Myatra, Sheila N., Ng Gong, Michelle, Papazian, Laurent, Patel, Bhakti K., Pellegrini, Mariangela, Perner, Anders, Pesenti, Antonio, Piquilloud, Lise, Grasselli, Giacomo, Calfee, Carolyn S., Camporota, Luigi, Poole, Daniele, Amato, Marcelo B.P., Antonelli, Massimo, Arabi, Yaseen M., Baroncelli, Francesca, Beitler, Jeremy R., Bellani, Giacomo, Bellingan, Geoff, Blackwood, Bronagh, Bos, Lieuwe D.J., Brochard, Laurent, Brodie, Daniel, Burns, Karen E.A., Combes, Alain, D’Arrigo, Sonia, De Backer, Daniel, Demoule, Alexandre, Einav, Sharon, Fan, Eddy, Ferguson, Niall D., Frat, Jean Pierre, Gattinoni, Luciano, Guérin, Claude, Herridge, Margaret S., Hodgson, Carol, Hough, Catherine L., Jaber, Samir, Juffermans, Nicole P., Karagiannidis, Christian, Kesecioglu, Jozef, Kwizera, Arthur, Laffey, John G., Mancebo, Jordi, Matthay, Michael A., McAuley, Daniel F., Mercat, Alain, Meyer, Nuala J., Moss, Marc, Munshi, Laveena, Myatra, Sheila N., Ng Gong, Michelle, Papazian, Laurent, Patel, Bhakti K., Pellegrini, Mariangela, Perner, Anders, Pesenti, Antonio, and Piquilloud, Lise

Abstract

The aim of these guidelines is to update the 2017 clinical practice guideline (CPG) of the European Society of Intensive Care Medicine (ESICM). The scope of this CPG is limited to adult patients and to non-pharmacological respiratory support strategies across different aspects of acute respiratory distress syndrome (ARDS), including ARDS due to coronavirus disease 2019 (COVID-19). These guidelines were formulated by an international panel of clinical experts, one methodologist and patients’ representatives on behalf of the ESICM. The review was conducted in compliance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statement recommendations. We followed the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach to assess the certainty of evidence and grade recommendations and the quality of reporting of each study based on the EQUATOR (Enhancing the QUAlity and Transparency Of health Research) network guidelines. The CPG addressed 21 questions and formulates 21 recommendations on the following domains: (1) definition; (2) phenotyping, and respiratory support strategies including (3) high-flow nasal cannula oxygen (HFNO); (4) non-invasive ventilation (NIV); (5) tidal volume setting; (6) positive end-expiratory pressure (PEEP) and recruitment maneuvers (RM); (7) prone positioning; (8) neuromuscular blockade, and (9) extracorporeal life support (ECLS). In addition, the CPG includes expert opinion on clinical practice and identifies the areas of future research.

Published
2023

27. Supplementary materials for 'Mixed methods study protocol for combining stakeholder-led rapid evaluation with near real-time continuous registry data to facilitate evaluations of quality of care in intensive care units'

Author

Rashan, Aasiyah, Beane, Abi, Ghose, Aniruddha, Dondorp, Arjen M, Kwizera, Arthur, Vijayaraghavan, Bharath Kumar Tirupakuzhi, Biccard, Bruce, Righy, Cassia, Thwaites, Louise, Pell, Christopher, Sendagire, Cornelius, Thomson, David, Aryal, Diptesh, Wagstaff, Duncan, Nadia, Farah, Putoto, Giovanni, Paneru, Hem Raj, Udayanga, Ishara, Amuasi, John, Salluh, Jorge, Gokhale, Krishna, Nirantharakumar, Krishnarajah, Pisani, Luigi, Hashmi, Madiha, Schultz, Marcus, Ghalib, Maryam Shamal, Mukaka, Mavuto, Mat-Nor, Mohammed Basri, Siaw-frimpong, Moses, Surenthirakumaran, Rajendra, haniffa, rashan, Kaddu, Ronnie P, Pinto Pereira, Snehal, Murthy, Srinivas, Harris, Steve, Moonesinghe, Suneetha Ramani, Vengadasalam, Sutharshan, Tripathy, Swagata, Gooden, Tiffany, Tolppa, Timo, Pari, Vrindha, Waweru-Siika, Wangari, and Minh, Yen Lam

Abstract

Supplemental materials for article titled 'Mixed methods study protocol for combining stakeholder-led rapid evaluation with near real-time continuous registry data to facilitate evaluations of quality of care in intensive care units'

Published
2023
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28. Current challenges in the management of sepsis in ICUs in resource-poor settings and suggestions for the future

Author

Schultz, Marcus J., Dunser, Martin W., Dondorp, Arjen M., Adhikari, Neill K. J., Iyer, Shivakumar, Kwizera, Arthur, and Lubell, Yoel

Subjects
Drug resistance in microorganisms -- Care and treatment, Infection -- Care and treatment, Medical colleges, Epidemiology, Company business management, Health care industry
Abstract

Background Sepsis is a major reason for intensive care unit (ICU) admission, also in resource-poor settings. ICUs in low- and middle-income countries (LMICs) face many challenges that could affect patient outcome. Aim To describe differences between resource-poor and resource-rich settings regarding the epidemiology, pathophysiology, economics and research aspects of sepsis. We restricted this manuscript to the ICU setting even knowing that many sepsis patients in LMICs are treated outside an ICU. Findings Although many bacterial pathogens causing sepsis in LMICs are similar to those in high-income countries, resistance patterns to antimicrobial drugs can be very different; in addition, causes of sepsis in LMICs often include tropical diseases in which direct damaging effects of pathogens and their products can sometimes be more important than the response of the host. There are substantial and persisting differences in ICU capacities around the world; not surprisingly the lowest capacities are found in LMICs, but with important heterogeneity within individual LMICs. Although many aspects of sepsis management developed in rich countries are applicable in LMICs, implementation requires strong consideration of cost implications and the important differences in resources. Conclusions Addressing both disease-specific and setting-specific factors is important to improve performance of ICUs in LMICs. Although critical care for severe sepsis is likely cost-effective in LMIC setting, more detailed evaluation at both at a macro- and micro-economy level is necessary. Sepsis management in resource-limited settings is a largely unexplored frontier with important opportunities for research, training, and other initiatives for improvement., Author(s): Marcus J. Schultz [sup.1] [sup.2], Martin W. Dunser [sup.3], Arjen M. Dondorp [sup.1] [sup.2], Neill K. J. Adhikari [sup.4], Shivakumar Iyer [sup.5], Arthur Kwizera [sup.6], Yoel Lubell [sup.2], Alfred [...]

Published
2017
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30. What's new in sepsis recognition in resource-limited settings?

Author

Kwizera, Arthur, Festic, Emir, and Dünser, Martin W.

Subjects
Medical colleges -- Health aspects, Infection -- Health aspects, Anesthesia -- Health aspects, Health care industry
Abstract

Author(s): Arthur Kwizera [sup.1], Emir Festic [sup.2], Martin W. Dünser [sup.3] Author Affiliations: (1) Department of Anaesthesia, Makerere University College of Health Sciences, Mulago National Referral Hospital, , Kampala, Uganda [...]

Published
2016
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33. Acute Respiratory Distress Syndrome in an African Intensive Care Unit Setting: A Prospective Study of Prevalence and Outcomes

Author

Kwizera, Arthur, primary, Kateete, David P., additional, Ssenyonga, Ronald, additional, Nakiyingi, Lydia, additional, Nakibuuka, Jane, additional, Namata, Christine, additional, Mwanje, Arthur, additional, Okello, Emmy, additional, Kabatoro, Daphne, additional, Kiwanuka, Noah, additional, Bollinger, Robert C., additional, Tumwine, James, additional, and Summers, Charlotte, additional

Published
2022
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35. A Research Agenda for Precision Medicine in Sepsis and Acute Respiratory Distress Syndrome: An Official American Thoracic Society Research Statement

Author

Shah, Faraaz Ali, primary, Meyer, Nuala J., additional, Angus, Derek C., additional, Awdish, Rana, additional, Azoulay, Élie, additional, Calfee, Carolyn S., additional, Clermont, Gilles, additional, Gordon, Anthony C., additional, Kwizera, Arthur, additional, Leligdowicz, Aleksandra, additional, Marshall, John C., additional, Mikacenic, Carmen, additional, Sinha, Pratik, additional, Venkatesh, Balasubramanian, additional, Wong, Hector R., additional, Zampieri, Fernando G., additional, and Yende, Sachin, additional

Published
2021
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36. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock 2021

Author

Evans, Laura, primary, Rhodes, Andrew, additional, Alhazzani, Waleed, additional, Antonelli, Massimo, additional, Coopersmith, Craig M., additional, French, Craig, additional, Machado, Flávia R., additional, Mcintyre, Lauralyn, additional, Ostermann, Marlies, additional, Prescott, Hallie C., additional, Schorr, Christa, additional, Simpson, Steven, additional, Wiersinga, W. Joost, additional, Alshamsi, Fayez, additional, Angus, Derek C., additional, Arabi, Yaseen, additional, Azevedo, Luciano, additional, Beale, Richard, additional, Beilman, Gregory, additional, Belley-Cote, Emilie, additional, Burry, Lisa, additional, Cecconi, Maurizio, additional, Centofanti, John, additional, Coz Yataco, Angel, additional, De Waele, Jan, additional, Dellinger, R. Phillip, additional, Doi, Kent, additional, Du, Bin, additional, Estenssoro, Elisa, additional, Ferrer, Ricard, additional, Gomersall, Charles, additional, Hodgson, Carol, additional, Hylander Møller, Morten, additional, Iwashyna, Theodore, additional, Jacob, Shevin, additional, Kleinpell, Ruth, additional, Klompas, Michael, additional, Koh, Younsuck, additional, Kumar, Anand, additional, Kwizera, Arthur, additional, Lobo, Suzana, additional, Masur, Henry, additional, McGloughlin, Steven, additional, Mehta, Sangeeta, additional, Mehta, Yatin, additional, Mer, Mervyn, additional, Nunnally, Mark, additional, Oczkowski, Simon, additional, Osborn, Tiffany, additional, Papathanassoglou, Elizabeth, additional, Perner, Anders, additional, Puskarich, Michael, additional, Roberts, Jason, additional, Schweickert, William, additional, Seckel, Maureen, additional, Sevransky, Jonathan, additional, Sprung, Charles L., additional, Welte, Tobias, additional, Zimmerman, Janice, additional, and Levy, Mitchell, additional

Published
2021
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38. Acid-Base disorders as predictors of early outcomes in major Trauma in a resource limited setting

Author

Asiimwe Ian Shane, Wangoda Robert, Kwizera Arthur, Makobore Patson, and Galukande Moses

Subjects
major trauma, anion gap, early outcome, organ failure, acidosis, Medicine
Abstract

INTRODUCTION: Mortality from trauma still remains a major challenge despite recent substantial improvements in acute trauma care. In trauma care patient resuscitation to correct hypotension from volume loss still majorly relies on use of physiological parameters such as blood pressure, pulse rate, respiratory rate, urine output, Glasgow coma scale and oxygen saturation in resource limited settings. In such settings, these methods may not be sufficient to detect occult tissue hypoxia, due to undetected hypotension and accompanying metabolic derangements.

Published
2014
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40. Safety and Efficacy of Hydroxychloroquine for Treatment of Non-Severe COVID-19 in Adults in Uganda: A Randomized Open Label Phase II Clinical Trial

Author

Byakika-Kibwika, Pauline, primary, Sekaggya-Wiltshire, Christine, additional, Semakula, Jerome Roy, additional, Nakibuuka, Jane, additional, Musaazi, Joseph, additional, Kayima, James, additional, Sendagire, Cornelius, additional, Meya, David, additional, Kirenga, Bruce, additional, Nanzigu, Sarah, additional, Kwizera, Arthur, additional, Nakwagala, Fred, additional, Kisuule, Ivan, additional, Wayengera, Misaki, additional, Mwebesa, Henry G, additional, Kamya, Moses, additional, and Bazeyo, William, additional

Published
2021
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41. Executive Summary:Surviving Sepsis Campaign: International Guidelines for the Management of Sepsis and Septic Shock 2021

Author

Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flávia R., Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Joost Wiersinga, W., Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Yataco, Angel Coz, De Waele, Jan, Dellinger, R. Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa, Ferrer, Ricard, Gomersall, Charles, Hodgson, Carol, Møller, Morten Hylander, Iwashyna, Theodore, Jacob, Shevin, Kleinpell, Ruth, Klompas, Michael, Koh, Younsuck, Kumar, Anand, Kwizera, Arthur, Lobo, Suzana, Masur, Henry, McGloughlin, Steven, Mehta, Sangeeta, Mehta, Yatin, Mer, Mervyn, Nunnally, Mark, Oczkowski, Simon, Osborn, Tiffany, Papathanassoglou, Elizabeth, Perner, Anders, Puskarich, Michael, Roberts, Jason, Schweickert, William, Seckel, Maureen, Sevransky, Jonathan, Sprung, Charles L., Welte, Tobias, Zimmerman, Janice, Levy, Mitchell, Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flávia R., Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Joost Wiersinga, W., Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Yataco, Angel Coz, De Waele, Jan, Dellinger, R. Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa, Ferrer, Ricard, Gomersall, Charles, Hodgson, Carol, Møller, Morten Hylander, Iwashyna, Theodore, Jacob, Shevin, Kleinpell, Ruth, Klompas, Michael, Koh, Younsuck, Kumar, Anand, Kwizera, Arthur, Lobo, Suzana, Masur, Henry, McGloughlin, Steven, Mehta, Sangeeta, Mehta, Yatin, Mer, Mervyn, Nunnally, Mark, Oczkowski, Simon, Osborn, Tiffany, Papathanassoglou, Elizabeth, Perner, Anders, Puskarich, Michael, Roberts, Jason, Schweickert, William, Seckel, Maureen, Sevransky, Jonathan, Sprung, Charles L., Welte, Tobias, Zimmerman, Janice, and Levy, Mitchell

Published
2021

42. Surviving sepsis campaign:international guidelines for management of sepsis and septic shock 2021

Author

Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flávia R., Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Wiersinga, W. Joost, Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Coz Yataco, Angel, De Waele, Jan, Dellinger, R. Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa, Ferrer, Ricard, Gomersall, Charles, Hodgson, Carol, Møller, Morten Hylander, Iwashyna, Theodore, Jacob, Shevin, Kleinpell, Ruth, Klompas, Michael, Koh, Younsuck, Kumar, Anand, Kwizera, Arthur, Lobo, Suzana, Masur, Henry, McGloughlin, Steven, Mehta, Sangeeta, Mehta, Yatin, Mer, Mervyn, Nunnally, Mark, Oczkowski, Simon, Osborn, Tiffany, Papathanassoglou, Elizabeth, Perner, Anders, Puskarich, Michael, Roberts, Jason, Schweickert, William, Seckel, Maureen, Sevransky, Jonathan, Sprung, Charles L., Welte, Tobias, Zimmerman, Janice, Levy, Mitchell, Evans, Laura, Rhodes, Andrew, Alhazzani, Waleed, Antonelli, Massimo, Coopersmith, Craig M., French, Craig, Machado, Flávia R., Mcintyre, Lauralyn, Ostermann, Marlies, Prescott, Hallie C., Schorr, Christa, Simpson, Steven, Wiersinga, W. Joost, Alshamsi, Fayez, Angus, Derek C., Arabi, Yaseen, Azevedo, Luciano, Beale, Richard, Beilman, Gregory, Belley-Cote, Emilie, Burry, Lisa, Cecconi, Maurizio, Centofanti, John, Coz Yataco, Angel, De Waele, Jan, Dellinger, R. Phillip, Doi, Kent, Du, Bin, Estenssoro, Elisa, Ferrer, Ricard, Gomersall, Charles, Hodgson, Carol, Møller, Morten Hylander, Iwashyna, Theodore, Jacob, Shevin, Kleinpell, Ruth, Klompas, Michael, Koh, Younsuck, Kumar, Anand, Kwizera, Arthur, Lobo, Suzana, Masur, Henry, McGloughlin, Steven, Mehta, Sangeeta, Mehta, Yatin, Mer, Mervyn, Nunnally, Mark, Oczkowski, Simon, Osborn, Tiffany, Papathanassoglou, Elizabeth, Perner, Anders, Puskarich, Michael, Roberts, Jason, Schweickert, William, Seckel, Maureen, Sevransky, Jonathan, Sprung, Charles L., Welte, Tobias, Zimmerman, Janice, and Levy, Mitchell

Published
2021

44. A living WHO guideline on drugs to prevent covid-19

Author

Lamontagne, François, primary, Stegemann, Miriam, additional, Agarwal, Arnav, additional, Agoritsas, Thomas, additional, Siemieniuk, Reed, additional, Rochwerg, Bram, additional, Bartoszko, Jessica, additional, Askie, Lisa, additional, Macdonald, Helen, additional, Al-Maslamani, Muna, additional, Amin, Wagdy, additional, Araujo Da Silva, Andre Ricardo, additional, Barragan, Fabian Alberto Jaimes, additional, Bausch, Frederique Jacquerioz, additional, Burhan, Erlina, additional, Cecconi, Maurizio, additional, Chacko, Binila, additional, Chanda, Duncan, additional, Dat, Vu Quoc, additional, Du, Bin, additional, Geduld, Heike, additional, Gee, Patrick, additional, Haider, Muhammad, additional, Harley, Nerina, additional, Hashimi, Madiha, additional, Jehan, Fyezah, additional, Hui, David, additional, Hunt, Beverley J, additional, Ismail, Mohamed, additional, Kabra, Sushil, additional, Kanda, Seema, additional, Kawano-Dourado, Leticia, additional, Kim, Yae-Jean, additional, Kissoon, Niranjan, additional, Krishna, Sanjeev, additional, Kwizera, Arthur, additional, Lisboa, Thiago, additional, Leo, Yee-Sin, additional, Mahaka, Imelda, additional, Hela, Manai, additional, Battista Migliori, Giovanni, additional, Mino, Greta, additional, Nsutebu, Emmanuel, additional, Pshenichnaya, Natalia, additional, Qadir, Nida, additional, Ranganathan, Shalini Sri, additional, Sabzwari, Saniya, additional, Sarin, Rohit, additional, Shankar-Hari, Manu, additional, Sharland, Michael, additional, Shen, Yinzhong, additional, Souza, Joao Paulo, additional, Tshokey, Tshokey, additional, Ugarte, Sebastian, additional, Uyeki, Tim, additional, Venkatapuram, Sridhar, additional, Wachinou, Ablo Prudence, additional, Wijewickrama, Ananda, additional, Vuyiseka, Dubula, additional, Preller, Jacobus, additional, Brignardello-Petersen, Romina, additional, Kum, Elena, additional, Qasim, Anila, additional, Zeraatkar, Dena, additional, Owen, Andrew, additional, Guyatt, Gordon, additional, Lytvyn, Lyubov, additional, Jacobs, Michael, additional, Vandvik, Per Olav, additional, and Diaz, Janet, additional

Published
2021
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45. Epidemiology and Clinical Outcomes of Adults with Acute Respiratory Failure in a Low-Income Country: A Prospective, Observational, Multicentre Cohort Study

Author

Kwizera, Arthur, primary, Kabatooro, Daphne, additional, sendagire, cornelius, additional, Nakibuuka, Jane, additional, Owachi, Darius, additional, Nsereko, Chris, additional, Ochieng, John-Paul, additional, Goretti Nampiina, Maria, additional, Nampaawu, Mary J., additional, Kakaire, Dennis, additional, Baluku, Morris, additional, Odwar, Eric, additional, Kateregga, George, additional, Dunsar, Martin, additional, Olaro, Charles, additional, Kyobe-Bosa, Henry, additional, Kirenga, Bruce J., additional, Nakiyingi, Lydia, additional, Byakiika-Kibwika, Pauline, additional, Kiwanuka, Noah, additional, Kateete, David Patrick, additional, Joloba, Moses, additional, Summers, Charlotte, additional, and Investigators, ARISE-Uganda, additional

Published
2021
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47. Acute hypoxaemic respiratory failure in a low-income country: a prospective observational study of hospital prevalence and mortality

Author

Kwizera, Arthur, primary, Nakibuuka, Jane, additional, Nakiyingi, Lydia, additional, Sendagire, Cornelius, additional, Tumukunde, Janat, additional, Katabira, Catherine, additional, Ssenyonga, Ronald, additional, Kiwanuka, Noah, additional, Kateete, David Patrick, additional, Joloba, Moses, additional, Kabatoro, Daphne, additional, Atwine, Diana, additional, and Summers, Charlotte, additional

Published
2020
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49. A living WHO guideline on drugs for covid-19

Author

Agarwal, Arnav, primary, Hunt, Beverley J, additional, Stegemann, Miriam, additional, Rochwerg, Bram, additional, Lamontagne, François, additional, Siemieniuk, Reed AC, additional, Agoritsas, Thomas, additional, Askie, Lisa, additional, Lytvyn, Lyubov, additional, Leo, Yee-Sin, additional, Macdonald, Helen, additional, Zeng, Linan, additional, Alhadyan, Ahmed, additional, Muna, Al-Maslamani, additional, Amin, Wagdy, additional, da Silva, André Ricardo Araujo, additional, Aryal, Diptesh, additional, Barragan, Fabian A Jaimes, additional, Bausch, Frederique J, additional, Burhan, Erlina, additional, Calfee, Carolyn S, additional, Cecconi, Maurizio, additional, Chacko, Binila, additional, Chanda, Duncan, additional, Dat, Vu Quoc, additional, De Sutter, An, additional, Du, Bin, additional, Freedman, Stephen, additional, Geduld, Heike, additional, Gee, Patrick, additional, Haider, Muhammad, additional, Gotte, Matthias, additional, Harley, Nerina, additional, Hashmi, Madiha, additional, Hui, David, additional, Ismail, Mohamed, additional, Jehan, Fyezah, additional, Kabra, Sushil K, additional, Kanda, Seema, additional, Kim, Yae-Jean, additional, Kissoo, Niranjan, additional, Krishna, Sanjeev, additional, Kuppalli, Krutika, additional, Kwizera, Arthur, additional, Castro-Rial, Marta Lado, additional, Lisboa, Thiago, additional, Lodha, Rakesh, additional, Mahaka, Imelda, additional, Manai, Hela, additional, Mendelson, Marc, additional, Battista Migliori, Giovanni, additional, Mino, Greta, additional, Nsutebu, Emmanuel, additional, Peter, Jessica, additional, Preller, Jacobus, additional, Pshenichnaya, Natalia, additional, Qadir, Nida, additional, Ranganathan, Shalini S, additional, Relan, Pryanka, additional, Rylance, Jamie, additional, Sabzwari, Saniya, additional, Sarin, Rohit, additional, Shankar-Hari, Manu, additional, Sharland, Michael, additional, Shen, Yinzhong, additional, Souza, Joao P, additional, Swanstrom, Ronald, additional, Tshokey, Tshokey, additional, Ugarte, Sebastian, additional, Uyeki, Timothy, additional, Vazquez Curiel, Evangelina, additional, Venkatapuram, Sridhar, additional, Vuyiseka, Dubula, additional, Wijewickrama, Ananda, additional, Tran, Lien, additional, Zeraatkar, Dena, additional, Bartoszko, Jessica J, additional, Ge, Long, additional, Brignardello-Petersen, Romina, additional, Owen, Andrew, additional, Guyatt, Gordon, additional, Diaz, Janet, additional, Kawano-Dourado, Leticia, additional, Jacobs, Michael, additional, and Vandvik, Per Olav, additional

Published
2020
Full Text
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