Search

Your search keyword '"Kwan, C."' showing total 1,349 results
Start Over Author "Kwan, C."
1,349 results on '"Kwan, C."'

2. Introduction

Author

Coakley, John, primary, Kwan, C. Nathan, additional, and Wilson, David, additional

Published
2024
Full Text
View/download PDF

3. Effect of the Factor XIa Inhibitor Asundexian According to Baseline Infarct Pattern and on MRI Covert Infarct Outcomes

Author

Smith, Eric E., Shoamanesh, Ashkan, Xu, Lizhen, Heenan, Laura, Saad, Feryal, Colorado, Pablo, Chen, Chih-Hao, Lemmens, Robin, De Marchis, Gian Marco, Caso, Valeria, Masjuan, Jaime, Hirano, Teruyuki, Milanov, Ivan, Campbell, Bruce C.V., Mas, Jean-Louis, Connolly, Stuart J., Mundl, Hardi, Hart, Robert G., Bailey, P., Kleinig, T., Cordato, D., Choi, P., Garcia-Esperon, C., Chew, A., Cloud, G., Stanislaus, V., Krause, M., Priglinger, M., Grimley, R., Ghia, D., Sahathevan, R., Brown, H., Kwan, C., Devlin, M., Greisenegger, S., Bonelli-Nauer, S., Rath, J., Langer, A., Marko, M., Ferrari, J., Bernegger, A., Baumgartinger, M., Vigl, M., Krebs, S., Lang, W., Knoflach, M., Dejakum, B., Kiechl, S., Töll, T., Domig, L., Mutzenbach, J.S., Ganser, B., Hecker, C., Rösler, C., Bubel, N., Pikija, S., Zellner, T., Leitner, U., Berger, O., Surböck, B., Beirer, S., Staykov, D., Schrammel, D., Halilovic, A., Frattner, M., Barmherzigen, D., Lampl, C., Höfer, C., Nagl, S., Bocksrucker, C., Demeestere, J., Desfontaines, P., Ciobanu, C., De Pauw, A., Terwecoren, A., Hasenbroekx, M.C., Clement, F., De Klippel, N., Soors, P., Hermans, S., De Raedt, S., Vandervorst, F., Seynaeve, L., Fockaert, N., Smet, S., Rutgers, M., Del Gaudio, N., Paindeville, P., Staikov, I., Simeonova, A., Stoyanova, I., Cholakova, M., Mihnev, N., Petrova, T., Koralova, A., Dimov, D., Kuzev, Y., Danovska, M., Marinova, D., Marinova-Trifonova, D., Ovcharova, E., Mladenovski, I., Yanakieva, M., Stoev, P., Dimitrova, M., Todorova-Georgieva, S., Haralanov, L., Milkov, B., Solakov, D., Petkova, N., Ignatova-Valkova, V., Karabinov, V., Marinova, V., Miteva, Y., Andonova, V., Kasabova, D., Kostadinova, E., Shopova-Vrabcheva, Y., Gatev, D., Semova, D., Halil, E., Kaprelyan, A., Ivanov, B., Panov, G., Grudkova, M., Syuleyman, N., Kalpachki, R., Alexiev, F., Ivanova, I., Kancheva, K., Sakelarova, T., Maslarov, D., Drenska, D., Georgiev, V., Petrova, K., Petrova, N., Ivanova, I., Semerdjieva, N., Zhelyazkov, P., Spasova-Markova, S., Dong, X., Wang, D., Wang, S., Huang, W., Zhao, H., Wang, C., Jie, L., Xinyang, Y., Ping, Z., Dong, Q., Wang, Y., Fuling, Y., Yue, W., Liu, R., Yang, Y., Stetkarova, I., Mikulenka, P., Vasko, P., Peisker, T., Bar, M., Roubec, M., Mikulik, R., Cabukova, M., Vinklarek, J., Kovar, M., Pansky, M., Mencl, P., Skoda, O., Carek, M., Pernicka, M., Skodova, M., Geier, P., Cepkova, J., Drlik, J., Prax, T., Herzig, R., Krajickova, D., Vitkova, E., Haluskova, S., Vaclavik, D., Martinkova, J., Blejcharova, K., Tkacova, M., Pavlik, O., Nevšímalová, M., Rosol, J., Nevsimalova, M., Hruby, R., Iversen, H., Andersen, A.V., Rahimi, D., Christensen, H., Grundtvig, J., Hjort, N., Andersen, G., Sandal, B., Stilund, M., Modrau, B., Strade, A., Porobic, M., Andersen, S.D., Kruuse, C., Ölmestig, J., Kolmos, M., Parvez, A., Christensen, T., Stokholm, J., Jensen, H.B., Putaala, J., Strbian, D., Sibolt, G., Tiainen, M., Martinez-Majander, N., Curtze, S., Raty, S., Kraemer, Y., Roine, R., Aivo, J., Ruuskanen, J., Ylikotila, P., Roine, S., Hallikainen, M., Jakala, P., Kurl, S., Julkunen, V., Sibon, I., Olindo, S., Richard, S., Larrue, V., Gollion, C., Catala, H., Henon, H., Lucie, D.S., Nelly, D., Calvet, D., Malbranque, A., Mazé, B., Barbieux-Ghitu, C., Rosso, C., Samson, Y., Vannier, S., Moulin, T., Bonnet, L., Reiner, P., Buffon, F., Denier, C., Amri, K., Legris, N., Chassin, O., Selli, N., Mariana, S., Berrouschot, J., Stoll, A., Klunk, D., Keilitz, J., Neustadt, M., Zerrenner, S., Veltkamp, R., Hajjar, K., Heeger, A., Winezki, E., Apel, L., Pompsch, M., Mueller, P., Rappard, P., Auer, R., Ringleb, P.A., Berberich, A., Heyse, M., Mundiyanapurath, S., Reiff, T., Poli, S., Gomez-Exposito, A., Mengel, A., Tünnerhoff, J., Adeyemi, K., Poli, K., Kusch, V., Pelz, J., Michalski, D., Wartenberg, K., Althaus, K., Tavares, F., Mueller, S., Soda, H., Rascher, A., Hiermann, E., Weinhardt, R., Weissenborn, K., Leotescu, A., Grosse, G., Worthmann, H., Ernst, J., Gabriel, M., Schuppner, R., Schäfer, J.H., Charisse, D., Gruber, K., Kurka, N., Reitz, S.C., Pfeilschifter, W., Lee, J.I., Gliem, M., Moll, M., Steiner, T., Segura, L., Szegedi, N., Barandi, D., Uhrinakova, L., Czencz, M., Pasztor, M., Gyuker, N., Bartha, N.E., May, Z., Simony, Z., Szasz, G., Kakuk, I., Pető, N., Panczel, G.F., Olah, A., Racz, O., Balla, T., Horvath, B., Tuba, K., Czinderi, V., Klivenyi, P., Annus, A., Hertelendy, P., Szapary, L., Bosnyak, E., Kalmar, P., Karadi, Z., Cziba, L., Olah, L., Berki, A., Hudak, L., Kozák, M., Babel, S., Nemeth, L., Molnár, B., Simon, Z., Roveri, L., Cerri, F., Giacalone, G., Zini, A., Mauro, G., Asioli, G.M., Forlivesi, S., Arnone, G., Fiaccadori, A., Maria Fontana Francesca, E., Allegra, G., Mosconi, M.G., Longoni, M., Terlizzi, R., Paolucci, M., Tassi, R., Franci, B., Lucani, B., Domenichelli, C., Paoletti, D., Acampa, M., Zedde, M.L., Pezzella, F.R., Mangiardi, M., Galizia, P., Anticoli, S., Scalise, S., Lattanzi, S., Norata, D., Cannuccia, M., Cavallini, A., Federica, F., Denaro, M.F., Tosi, P., Sonoda, K., Kawajiri, M., Kusano, Y., Haraguchi, K., Kawano, H., Terasaki, T., Kaneko, C., Murase, S., Kumagai, M., Murai, N., Miyazaki, Y., Mori, T., Hatano, T., Kawanishi, M., Ochiai, J., Ishihara, S., Uehara, T., Yasaka, M., Nakagawa, H., Makino, M., Yonehara, T., Fukushima, Y., Hirotsune, N., Sakai, N., Yamasaki, M., Coutinho, J., Wouters, A., den Hertog, H., Zwartbol, R., Beumer, D., Kerklaan, J., Hilkens, P., Schreuder, T., Propper, D., Slowik, A., Wlodarczyk, E., Wrona, P., Pulyk, R., Lasek-Bal, A., Kosarz-Lanczek, K., Puz, P., Bilik, M., Magielska, A., Zamiela – Żółciak, A., Ochocinska, L., Bahdasaryan, S., Stępień, A., Dębiec, A., Joanna, K., Pawel, M., Jacek, S., Daniel, P., Marta, S., Rejdak, K., Wojczal, J., Luchowski, P., Fryze, W., Wisniewska, A., Krzyzanowska, M., Skowron, P., Wolosz, A., Galan, A., Grzymala, K., Krajewska, M., Nowak, R., Kłos, M., Cruz, V., Castro, P., Ferro, J., Canhão, P., Gouveia, R., Inácio, N., Rodrigues, M., Rachão, A., Ionel, C., Pereira, L., Viana-Baptista, M., Machado, C., Fernandes, C., Sargento, J., Inácio, N., Timchenko, L., Mironova, J., Zhadan, O., Torgashova, A., Bazhenova, O., Barashenkova, M., Kireeva, M., Romadina, N., Stepanova, I., Lenskaya, L., Lukinykh, L., Vorontsova, T., Agafina, A., Fedorova, A., Yashina, A., Alasheev, A., Smolkin, A., Prazdnichkova, E., Lutskovich, O., Gonysheva, Y., Mordvintseva, E., Nechaev, A., Martynova, E., Fedoraeva, N., Vishnyakova, T., Popov, D., Merzliakova, A., Margarita, K., Rechkalova, L., Ilyina, A., Kurenkova, N., Barbarash, O., Bazdyrev, E., Zvereva, T., Hromova, A., Morkvenas, A., Postnikova, E., Kovalenko, G., Taran, I., Pavlov, L., Ott, M., Chernitsova, N., Vodopyanova, N., Drozdova, E., Korebo, E., Lobanova, M., Lazareva, N., Snegova, N., Nikolaeva, O., Kolesnikov, Y., Kosheleva, Y., Krastev, G., Tomasova, K., Danis, M., Mako, M., Jankovicova, Z., Stevkova, Z., Kovacik, M., Kubikova, T., Jarosova, A., Serdahely, V., Cilingova, I., Pribulova, I., Sedlak, J., Slebodova, K., Paldaufova, M., Risnovsky, R., Berndtova, B., Urbanova, I., Junas, R., Karapetian, S., Gurcik, L., Vantrobova, A., Verbovsky, F., Vanacka, K., Ferenc, M., Galik, P., Bucakova, S., Ferencova, M., Kubalova, P., Boksanska, Z., Zacharova, E., Mahundi, E., Judita, H., Bachnak, M., Turcani, P., Kvasnicova Kamenska, A., Jurik, M., Vestenicka, V., Kycina, M., Sagatova, E., Dvorak, M., Hlubekova, A., Kucera, C., Gernath, L., Ferenc, M., Frimmelova, P., Slebodnikova, J., Aksteinerova, N., Horny, V., Gregova, Z., Segura, T., Romero, C., Ayo, O., Masjuan Vallejo, J., Cruz, A., De felipe, A, Matute, M.C., Garcia, S., Tembl Ferrairo, J., Vielba, I., Morales Caba, L., Molina, C., Garcia-Tornel García-Camba, Á., Requena Ruiz, M., Noelia, R., Rodriguez-Yañez, M., Rodriguez Castro, E., Lopez, I., Santamaria, M., Arias, S., Purroy García, F., Vázquez Justes, D., Mauri Capdevila, G., Vicente Pascual, M., Martí Fabregas, J., Camps Renom, P., Rodríguez Campello, A., Giralt, E., Krupinski, J., Molina, J., Trillo Senin, C. Ramos Martin, S., De La Fuente Sanz, E., Moniche, F., Manuel, M.R., Pardo, B., Martínez, I., Hernández Pérez, M., Arenillas Lara, J.F., De Lera, M., Egido, J.A., Gomez Escalonilla, C., Guillan, M., Martinez, J., Lindgren, A., Andsberg, G., Wictor, L., Leonidou, M., Stenman, M., Dalberg, N., Laska, A.C., Grünfeldt, A., Lundström, A., Nadzjafov, E., Rooth, E., Dalenbring, I., Sandén, P., Johansson, E., Thomas, G., Zietz, A.V., Rudin, S., Dittrich, T.D., Lilian, K., Kägi, G., Vehoff, J., Arnold, M., Scutelnic, A., Clénin, L., Beyeler, M., Madlaine, M., Maamari, B., Siepen, B., Vynckier, J., Tarnutzer, A., Bertschi, D., Luciani, M., Cereda, C., Maulucci, F., Bianco, G., Shairin, S., Pihan, H.A., Salmen, S., Quinn, T., McAlpine, C., Wright, F., Kalladka, D., Taylor, E., Sohaa, J., Brown, Z., Dawson, J., Cameron, A., Muir, S., Dima, S., Khan, U., Zhang, L., Warburton, E., Chatterjee, K., Nallasivan, A., Curran, D., Haider, S., Ghani, U., Kenton, A., Dallol, B., Mirza, M., Menezes, B., Davies, R., Robinson, T.G., Manning, L., Sztriha, L., Phinney, T., Sethi, P., Altafullah, I., Sharaf, A., Ostrander, M., Renati, S., Burgin, W.S., Olds, K., Delio, P., Malek, A., Dissin, J., Khatri, P., Flaherty, M., Demel, S., and Dofitas, S.

Published
2024
Full Text
View/download PDF

4. Application of Surface-Modified Nanosilica for Performance Enhancement of Asphalt Pavement

Author

He, D., Chan, H. H., Xiao, Z. H., Wu, T., Leung, L. M., Sham, M., Chen, B., Lee, S. F. S., Kwan, C. K. K., di Prisco, Marco, Series Editor, Chen, Sheng-Hong, Series Editor, Vayas, Ioannis, Series Editor, Kumar Shukla, Sanjay, Series Editor, Sharma, Anuj, Series Editor, Kumar, Nagesh, Series Editor, Wang, Chien Ming, Series Editor, Duan, Wenhui, editor, Zhang, Lihai, editor, and Shah, Surendra P., editor

Published
2023
Full Text
View/download PDF

5. Universal voltage scaling due to self-averaging of the quantum corrections in graphene

Author

Somphonsane, R., Ramamoorthy, H., He, G., Nathawat, J., Yin, S., Bird, J. P., Kwan, C. -P., Arabchigavkani, N., Barut, B., Zhao, M., Jin, Z., and Fransson, J.

Subjects
Condensed Matter - Mesoscale and Nanoscale Physics, Condensed Matter - Disordered Systems and Neural Networks
Abstract

The differential conductance of graphene is shown to exhibit a zero-bias anomaly at low temperatures, arising from a suppression of the quantum corrections due to weak localization and electron interactions. A simple rescaling of these data, free of any adjustable parameters, shows that this anomaly exhibits a universal, temperature- ($T$) independent form. According to this, the differential conductance is approximately constant at small voltages ($V

Published
2018

9. Accuracy versus speed in fluctuation-enhanced sensing

Author

Makra, P., Topalian, Z., Granqvist, C. G., Kish, L. B., and Kwan, C.

Subjects
Physics - Data Analysis, Statistics and Probability
Abstract

Fluctuation-enhanced sensing comprises the analysis of the stochastic component of the sensor signal and the utilization of the microscopic dynamics of the interaction between the agent and the sensor. We study the relationship between the measurement time window and the statistical error of the measurement data in the simplest case, when the output is the mean-square value of the stochastic signal. This situation is relevant at any practical case when the time window is finite, for example, when a sampling of the output of a fluctuation-enhanced array takes place; or a single sensor's activation (temperature, etc) is stepped up; or a single sensor's output is monitored by sampling subsequently in different frequency windows. Our study provides a lower limit of the relative error versus data window size with different types of power density spectra: white noise, 1/f (flicker, pink) noise, and 1/f^2 (red) noise spectra., Comment: Accepted for publication in Fluctuation and Noise Letters (acceptance in September 2011)

Published
2011

17. Service Learning in Medical and Nursing Training: A Randomized Controlled Trial

Author

Leung, A. Y. M., Chan, S. S. C., and Kwan, C. W.

Abstract

The purpose of this study was to explore the long term effect of a service learning project on medical and nursing students' knowledge in aging and their attitudes toward older adults. A total of 124 students were recruited and then randomized to intervention group (IG) and control group (CG). A pre-and-post-intervention design measured students' knowledge in aging (using modified Palmore's Fact on Aging Quiz) and attitudes toward older adults (using Kogan's Old People Scale). A total of 103 students completed all the activities and questionnaires. After the intervention, there were significant differences between the IG and CG on Palmore's mental health (MH) (P = 0.04), Palmore's total score (P = 0.02) and Kogan's negative attitudes toward older adults (P = 0.001). All students increased their positive attitude toward older adults after the intervention. However, both the IG and CG showed a decrease in positive attitudes 1 month after the interventon, and such decrease varied, depending on the programme which students attended. The current study showed that the 10-week service learning activities significantly increased medical and nursing students' overall knowledge of aging and their understanding of mental health needs in old age, and reduced their negative attitudes toward older adults. However, the effect is not long-lasting. On the other hand, its effect on positive attitudes toward older adults cannot be concluded. Periodic contacts with older adults via service learning activities may be needed to sustain attitude change toward older adults. (Contains 3 tables and 5 figures.)

Published
2012
Full Text
View/download PDF

21. The concerns and experiences of patients with lumbar spinal stenosis regarding prehabilitation and recovery after spine surgery: A qualitative study

Author

Lam, A. K. H., Fung, O. H. Y., Kwan, C., Cheung, J. P. Y., Luk, K D. K., Chiu, A. Y. Y., Descarreaux, M., Szeto, G. P. Y., Wong, A. Y. L., Lam, A. K. H., Fung, O. H. Y., Kwan, C., Cheung, J. P. Y., Luk, K D. K., Chiu, A. Y. Y., Descarreaux, M., Szeto, G. P. Y., and Wong, A. Y. L.

Abstract

Objectives To improve our understanding of patients’ perspectives regarding: (1) the decision making and prehabilitation before lumbar spinal stenosis (LSS) surgery; and (2) their postoperative experiences. Design Qualitative research with semi-structured interviews. Setting General community Participants Individuals received (n=10) and did not receive (n=15) prehabilitation before LSS surgery were recruited at the 6-month postoperative follow-up (8 females; average age: 67.7±6.7 years) by purposive sampling. Additionally, one participant invited her daughter to accompany her in an interview. Interventions Not applicable Main outcome measures Concerns and experiences of patients with LSS regarding prehabilitation and recovery after spine surgery. Results Thematic analysis was conducted to identify four themes inductively: (1) sources of information about LSS surgery; (2) factors affecting the surgical decision making; (3) attitudes toward prehabilitation; and (4) postoperative recovery. All participants desired to have more preoperative education to inform their surgical decision making. There were mixed opinions regarding the perceived benefits of prehabilitation because some individuals hesitated to participate in prehabilitaiotn due to their symptoms, or the cost or time of travelling. Many participants expected some or even complete relief of LSS-related symptoms after surgery. However, not all participants experienced the expected postoperative improvements. Some participants only experienced temporary symptomatic relief, while others experienced new postoperative symptoms. Patients generally found that postoperative exercises taught by physiotherapists were useful although their compliance decreased over time. Conclusions Our study highlights the need for better preoperative LSS education. Since face-to-face prehabilitation or postoperative rehabilitation may not be feasible for all patients, future studies should explore whether online-based prehabilitation o

Published
2022

23. Anatomy of spacetime and possible origins of internal symmetry and all particle quantum numbers

Author

Kwan C. Chiang

Subjects
Physics, Theoretical physics, Spacetime, Internal symmetry, General Physics and Astronomy, Particle, Quantum number
Abstract

Not driven by observations, this paper digs into the “internal workings” of spacetime. Through logical deductions, micro dimensions appear to be uncovered, with possible SU(4) or SU(5): 1. It is thought that special relativity merely initiated the definition of spacetime, but more scales are yet to be defined. 2. In the definition of spacetime, EM (electromagnetism) played another critical role, i.e., the six circular magnetic and electric field lines (running on the six planes) cross and “define equivalencies” between the four linear scales. Without this definition, light would not be measured at the same speed in different directions. Being a gauge theory, EM defines two things: Linear scales and “equivalencies” between linear scales. 3. For any scale (and their equivalencies), there could be no or many arbitrarily assumed definitions, or a concrete definition based on relevant physics. Nature would conform with but the one based on relevant physics, because Nature itself is consisted of that relevant physics. Thus, the principle: No scale and their equivalencies are meaningful unless defined by relevant physics. 4. Then, what are those fields running (and defining equivalencies between the six “angle scales”) on the six planes of the 4D spacetime? It is believed to be the “classical” weak fields which run in solid angles (or “3D angles”) between the six planes. (The only suspicion is that this rotation does not preserve vector length, which is not a problem ultimately.) 5. If the six angle scales are drawn as six axes of a 6D superspace, then the “3D angle” rotations look like “plane angle” rotations and cause SO(6)∼SU(4) [or SO(10)∼SU(5) for 5D spacetime], which appears to match baryon spectrum without quarks. 6. Since this rotation is between “planes” of the “external” spacetime, no linear dimension is visible, yet causing P-violations. 7. Similarly, fields running in 4D and 5D angle rotations (between 3D and 4D surfaces) must also exist, which may be responsible for CP-violation and strong interactions. 8. The 5D angle rotations may be generating Baryon and Lepton numbers and hence explaining their conservation behaviors, e.g., no proton decay. 9. It can be inferred, if 3D, 4D (and 5D) angle rotation fields did not exist, the 4D (and 5D) spacetime would be warped and the four (or five) linear axes would not be perpendicular to each other. 10. EM was simplified and turned elegant “only” after redefinition of spacetime by special relativity. Likewise, weak, CP-violation and strong interactions are expected to simplify and turn as elegant as EM when 2D (plane), 3D, and 4D angle scales are defined by weak, CP-violation, and strong forces, respectively. 11. Verifications as accurate as EM are expected too. 12. Mathematically, higher angle rotations thought to be inexistent only because it does not conserve vector length. Actually, they did not vanish and their symmetries would surface in particle classifications when linear momentum is not concerned. Micro dimensions being invisible is because symmetries do not have to happen between linear axes, but can happen between 2-, 3- or 4-surfaces. These geometries together generate the complete particles spectrum.

Published
2020
Full Text
View/download PDF

39. Comparison Study of Psychophysiological State Changes by Workshop Healing Program

Author

Hyong, Y.C., Lee, J.S., Joo, Mi.S., and Kwan, C.

Subjects
Job stress, Vibraimage, Polygraph investigation, Psychophysiology, Brain fatigue
Abstract

It is known that about 19.9% of scientific investigators are vulnerable to post-traumatic stress disorder due to frequent contact with shocking cases such as murder and decomposing bodies. Korean National Police Agency's bureau has conducted workshop program to strengthen their psychological capabilities. As a result, the quantitative measurement of psychophysiological state and workshop effects of agents was required, and psychophysiological state of agents before and after the workshop was measured using vibraimage technology. Before and After workshop, the average level of brain fatigue conditions, in a comprehensive indicator of Vibraimage parameters, changed from 0.09 to –1.03. The effects of the workshop could not be satisfactorily determined due to the lack of statistically significant differences. Brain fatigue conditions are correlated with positive emotion variables, indicating that the increase or decrease in positive emotion variables is largely affected by the brain fatigue state.

Published
2020
Full Text
View/download PDF

40. Voice driven applications in non-stationary and chaotic environment

Author

Kwan, C., Li, X., Lao, D., Deng, Y., Ren, Z., Raj, B., Singh, R., and Stern, R.

Subjects
Speech recognition software -- Usage, Voice recognition software, Computers and office automation industries, High technology industry
Abstract

Abstract--Automated operations based on voice commands will become more and more important in many applications, including robotics, maintenance operations, etc. However, voice command recognition rates drop quite a lot under [...]

Published
2006

41. Continuous feature adaptation for non-native speech recognition

Author

Deng, Y., Li, X., Kwan, C., Raj, B., and Stern, R.

Subjects
Computers and office automation industries, High technology industry
Abstract

Abstract--The current speech interfaces in many military applications may be adequate for native speakers. However, the recognition rate drops quite a lot for non-native speakers (people with foreign accents). This [...]

Published
2006

46. The effect of vitamin D supplementation on muscle strength in community-dwelling postmenopausal Asian women: a scoping review.

Author

Kwan, C. Y.

Abstract

Approximately 40% of the community-dwelling population aged over 65 experiences falls annually, leading to significant morbidity, immobility, and mortality, with reduced muscle strength identified as a major risk factor(1). In comparison to other ethnic populations, Asian older adults often demonstrate weaker muscle strength, with this decline accelerating notably in female Asian older adults as they age(2). Existing research indicates a correlation between vitamin D deficiency (circulating level of 25(OH)D below 50 nmol/L) and sarcopenia in community-dwelling older adults(3). Postmenopausal women, experiencing a decline in oestrogen, face an elevated risk of vitamin D deficiency(4). Notably, vitamin D deficiency is prevalent in Asian populations(5). However, the effectiveness of vitamin D supplementation in promoting muscle strength among community-dwelling postmenopausal Asian women has not been comprehensively investigated. This scoping review aims to provide an overview and synthesis of existing evidence in the literature concerning the efficacy of vitamin D supplementation in enhancing muscle strength among community-dwelling postmenopausal Asian women. A scoping review was conducted in accordance with PRISMA-ScR recommendations(6). Randomised controlled trials (RCTs) published from 2013 to 2023 were identified through searches conducted in PubMed, EMBASE, and the Cochrane Central databases. Articles would be included if they: (i) were human RCTs with a cross-over or parallel design, (ii) included community-dwelling postmenopausal women, and (iii) investigated the effect of vitamin D supplementation on muscle strength. The review excluded: (i) in vivo animal studies, in vitro cell research, case reports, and observational studies; (ii) studies investigating the effect of vitamin D supplementation combined with other interventions, such as physical exercise, amino acid supplements, or other medication administration records like insulin or hormone therapy; and (iii) studies not in English. Following deduplication and relevance screening, five studies met the criteria, with Jadad scores (methodological quality assessment) of 1, 3, 5, 5, and 5, respectively. Five RCTs involving a total of 872 subjects were reviewed(7–11). The three studies with Jadad scores of 5 indicated statistically significant and meaningful increases in muscle strength, measured by handgrip strength, with p-values <0.05 and effect sizes of 0.97, 1.75, and 3.83, respectively, indicating large effect sizes. The study with a Jadad score of 3 highlighted such increases only in the younger subgroup (<68 years old). Conversely, the study with a Jadad score of 1 suggested no significant changes in muscle strength. In conclusion, this review suggests promising outcomes for vitamin D supplementation in enhancing muscle strength among postmenopausal Asian women. The prevalence of vitamin D deficiency underscores potential health benefits, but heterogeneity in study designs, Jadad scores, and age subgroup responses necessitates cautious interpretation. Further high-quality research is imperative to elucidate optimal dosages and durations, ensuring a nuanced understanding of the relationship between vitamin D supplementation and muscle strength. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

49. The Intersection between Oral Microbiota, Host Gene Methylation and Patient Outcomes in Head and Neck Squamous Cell Carcinoma

Author

Chen, Zigui, primary, Wong, Po Yee, additional, Ng, Cherrie W. K., additional, Lan, Linlin, additional, Fung, Sherwood, additional, Li, Jing W., additional, Cai, Liuyang, additional, Lei, Pu, additional, Mou, Qianqian, additional, Wong, Sunny H., additional, Wu, William K. K., additional, Li, Ryan J., additional, Meehan, Katie, additional, Lui, Vivian W. Y., additional, Chow, Chit, additional, Lo, Kwok W., additional, Chan, Amy B. W., additional, Boon, Siaw Shi, additional, Lau, Eric H. L., additional, Yeung, Zenon, additional, Chan, Kwan C. Allen, additional, Wong, Eddy W. Y., additional, Cheng, Alfred S. L., additional, Yu, Jun, additional, Chan, Paul K. S., additional, and Chan, Jason Y. K., additional

Published
2020
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results