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2. AB1645-PARE DISEASE FLARES IN PATIENTS WITH RHEUMATOID ARTHRITIS FOLLOWING COVID-19 BREAKTHROUGH INFECTION: RESULT FROM COVAD E-SURVEY STUDY

Author

Sieiro Santos, C., primary, Chen, J. P., additional, Nikiphorou, E., additional, Tseng, C. W., additional, Toro-Gutierrez, C. E., additional, Tan, A. L., additional, Nune, A., additional, Kadam, E., additional, Kuwana, M., additional, Day, J., additional, Saha, S., additional, Velikova, T., additional, Lilleker, J. B., additional, Vinicio Caballero, C., additional, Sen, P., additional, Chinoy, H., additional, Aggarwal, R., additional, Agarwal, V., additional, Gupta, L., additional, and Chen, Y. M., additional

Published
2024
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4. POS0558 FLARES OF AUTOIMMUNE RHEUMATIC DISEASE FOLLOWING COVID-19 INFECTION: OBSERVATIONS FROM THE COVAD STUDY

Author

Ravichandran, N., primary, Sandhu, N., additional, Nune, A., additional, Day, J., additional, Sen, P., additional, Nikiphorou, E., additional, Tan, A. L., additional, Joshi, M., additional, Saha, S., additional, Katsuyuki Shinjo, S., additional, Jagtap, K., additional, Agarwal, V., additional, Ziade, N., additional, Velikova, T., additional, Milchert, M., additional, Kuwana, M., additional, Makol, A., additional, Chinoy, H., additional, Aggarwal, R., additional, and Gupta, L., additional

Published
2023
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5. OP0238 IMMUNOSUPPRESSION WITH TARGETED DMARDS REDUCES MORBIDITY AND MORTALITY IN PRE-CAPILLARY PULMONARY HYPERTENSION ASSOCIATED WITH SYSTEMIC SCLEROSIS: A EUSTAR ANALYSIS

Author

Bruni, C., primary, Tofani, L., additional, Fretheim, H., additional, Weber, Y., additional, Hachulla, E., additional, Carreira, P., additional, Giuggioli, D., additional, Airò, P., additional, Siegert, E., additional, Müller-Ladner, U., additional, Matucci-Cerinic, M., additional, Riemekasten, G., additional, Simeon Aznar, C. P., additional, De Vries-Bouwstra, J., additional, Saketkoo, L. A., additional, Distler, J., additional, Balbir-Gurman, A., additional, Castellví, I., additional, Zanatta, E., additional, Smith, V., additional, Denton, C. P., additional, Maurer, B., additional, Giollo, A., additional, Iannone, F., additional, Dagna, L., additional, Truchetet, M. E., additional, Kuwana, M., additional, Allanore, Y., additional, Tanaka, Y., additional, Martin, M., additional, Rosato, E., additional, Gheorghiu, A. M., additional, Del Galdo, F., additional, Solanki, K., additional, Vacca, A., additional, Resende, C., additional, Vieira, S., additional, Czirják, L., additional, Baresic, M., additional, Cantatore, F. P., additional, Riccieri, V., additional, Andréasson, K., additional, Chung, L., additional, Souza Muller, C., additional, Opris-Belinski, D., additional, Rednic, S., additional, Sfikakis, P., additional, Levy, Y., additional, Hsu, V., additional, Heitmann, S., additional, Henes, J., additional, Moroncini, G., additional, Iudici, M., additional, De Langhe, E., additional, Herrick, A., additional, Montecucco, C., additional, Hoffmann-Vold, A. M., additional, and Distler, O., additional

Published
2023
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6. POS1216 MULTIMORBIDITY AND PROMIS HEALTH OUTCOMES IN PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES: DATA FROM A LARGE, GLOBAL E-SURVEY (COVAD STUDY)

Author

Fornaro, M., primary, Venerito, V., additional, Iannone, F., additional, Ravichandran, N., additional, Nikiphorou, E., additional, Joshi, M., additional, Tan, A. L., additional, Saha, S., additional, Katsuyuki Shinjo, S., additional, Agarwal, V., additional, Ziade, N., additional, Velikova, T., additional, Jagtap, K., additional, Milchert, M., additional, Parodis, I., additional, Gracia-Ramos, A. E., additional, Cavagna, L., additional, Kuwana, M., additional, Knitza, J., additional, Makol, A., additional, Dzifa, D., additional, Toro Gutierrez, C. E., additional, Vinicio Caballero, C., additional, Distler, O., additional, Day, J., additional, Study, C., additional, Chinoy, H., additional, Aggarwal, R., additional, and Gupta, L., additional

Published
2023
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8. POS0573 COMORBIDITIES, COMPLEX MULTIMORBIDITY AND PROMIS HEALTH OUTCOMES AMONGAUTOIMMUNE RHEUMATIC DISEASES: DATA FROM THE COVAD STUDY

Author

Gupta, L., primary, Ravichandran, N., additional, Venerito, V., additional, Dey, M., additional, Sen, P., additional, Saha, S., additional, Tan, A. L., additional, Katsuyuki Shinjo, S., additional, Agarwal, V., additional, Joshi, M., additional, Ziade, N., additional, Velikova, T., additional, Jagtap, K., additional, Milchert, M., additional, Parodis, I., additional, Gracia-Ramos, A. E., additional, Cavagna, L., additional, Kuwana, M., additional, Knitza, J., additional, Makol, A., additional, Dzifa, D., additional, Toro Gutierrez, C. E., additional, Vinicio Caballero, C., additional, Distler, O., additional, Day, J., additional, Chinoy, H., additional, Aggarwal, R., additional, and Nikiphorou, E., additional

Published
2023
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9. POS0273 POST COVID-19 SYNDROME IN PATIENTS WITH AUTOIMMUNE RHEUMATIC DISEASES: RESULTS FROM THE COVAD STUDY

Author

Sen, P., primary, Ravichandran, N., additional, Joshi, M., additional, Saha, S., additional, Jagtap, K., additional, Agarwal, V., additional, Distler, O., additional, Nikiphorou, E., additional, Tan, A. L., additional, Katsuyuki Shinjo, S., additional, Ziade, N., additional, Velikova, T., additional, Milchert, M., additional, Parodis, I., additional, Gracia-Ramos, A. E., additional, Cavagna, L., additional, Kuwana, M., additional, Knitza, J., additional, Makol, A., additional, Patel, A., additional, Pauling, J., additional, Wincup, C., additional, Barman, B., additional, Zamora-Tehozol, E. A., additional, Rojas-Serrano, J., additional, Garcia-De La Torre, I., additional, Colunga-Pedraza, I. J., additional, Merayo-Chalico, J., additional, Katchamart, W., additional, Goo, P. A., additional, Chen, Y. M., additional, Hoff, L. S., additional, Kibbi, L., additional, Halabi, H., additional, Vaidya, B., additional, Shaharir, S. S., additional, Shumnalieva, R., additional, Hasan, A. T. M. T., additional, Dzifa, D., additional, Toro Gutierrez, C. E., additional, Vinicio Caballero, C., additional, Lilleker, J. B., additional, Salim, B., additional, Gheita, T. A., additional, Chatterjee, T., additional, Nune, A., additional, Saavedra, M. A., additional, Day, J., additional, Chinoy, H., additional, Aggarwal, R., additional, and Gupta, L., additional

Published
2023
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10. POS1254 REDUCED HEALTH-RELATED QUALITY OF LIFE USING PROMIS IN PATIENTS WITH SYSTEMIC SCLEROSIS: A CROSS-SECTIONAL ANALYSIS FROM THE INTERNATIONAL COVAD-2 E-SURVEY

Author

Yomono, K., primary, Li, Y., additional, Maroufy, V., additional, Ravichandran, N., additional, Yoshida, A., additional, Jagtap, K., additional, Velikova, T., additional, Sen, P., additional, Cavagna, L., additional, Agarwal, V., additional, Knitza, J., additional, Makol, A., additional, Dzifa, D., additional, Toro Gutierrez, C. E., additional, Chatterjee, T., additional, Patel, A., additional, Aggarwal, R., additional, Gupta, L., additional, and Kuwana, M., additional

Published
2023
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12. POS1231 IMPAIRED HEALTH-RELATED QUALITY OF LIFE IN PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES: A CROSS-SECTIONAL ANALYSIS FROM AN INTERNATIONAL E-SURVEY

Author

Yoshida, A., primary, LI, Y., additional, Maroufy, V., additional, Kuwana, M., additional, Ravichandran, N., additional, Makol, A., additional, Sen, P., additional, Lilleker, J. B., additional, Agarwal, V., additional, Kardes, S., additional, Day, J., additional, Milchert, M., additional, Joshi, M., additional, Gheita, T. A., additional, Salim, B., additional, Velikova, T., additional, Gracia-Ramos, A. E., additional, Parodis, I., additional, Nikiphorou, E., additional, Tan, A. L., additional, Nune, A., additional, Cavagna, L., additional, Saavedra, M. A., additional, Katsuyuki Shinjo, S., additional, Ziade, N., additional, Knitza, J., additional, Distler, O., additional, Chinoy, H., additional, Aggarwal, R., additional, and Gupta, L., additional

Published
2023
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13. OP0128 PHARMACOKINETICS AND PHARMACODYNAMICS OF METHOTREXATE POLYGLUTAMATE IN PATIENTS WITH RHEUMATOID ARTHRITIS TREATED WITH LOW OR HIGH DOSE-METHOTREXATE IN COMBINATION WITH ADALIMUMAB: RESULTS FROM THE MIRACLE TRIAL

Author

Tamai, H., primary, Ikeda, K., additional, Miyamoto, T., additional, Taguchi, H., additional, Kuo, C. F., additional, Shin, K., additional, Hirata, S., additional, Okano, Y., additional, Sato, S., additional, Yasuoka, H., additional, Choi, I. A., additional, Park, S. H., additional, Weng, M. Y., additional, Kuwana, M., additional, Lee, Y. J., additional, Ishii, T., additional, Kim, J., additional, Kameda, H., additional, Kojima, T., additional, Baek, H. J., additional, Hsu, P. N., additional, Huang, C. M., additional, Cheng, T. T., additional, Sung, W. Y., additional, Tsai, W. C., additional, Taninaga, T., additional, Mori, M., additional, Miyagishi, H., additional, Sato, Y., additional, Takeuchi, T., additional, and Kaneko, Y., additional

Published
2023
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14. POS0880 COMPARATIVE DISEASE BURDEN IN PATIENTS WITH RHEUMATOID ARTHRITIS, PSORIATIC ARTHRITIS OR ANKYLOSING SPONDYLITIS: DATA FROM COVAD PATIENT-REPORTED E-SURVEY

Author

Venerito, V., primary, Fornaro, M., additional, Iannone, F., additional, Cavagna, L., additional, Kuwana, M., additional, Agarwal, V., additional, Ravichandran, N., additional, Day, J., additional, Joshi, M., additional, Saha, S., additional, Shaharir, S. S., additional, Katchamart, W., additional, Goo, P. A., additional, Traboco, L., additional, Chen, Y. M., additional, Sen, P., additional, Lilleker, J. B., additional, Nune, A., additional, Pauling, J., additional, Wincup, C., additional, Tan, A. L., additional, Ziade, N., additional, Milchert, M., additional, Gracia-Ramos, A. E., additional, Vinicio Caballero, C., additional, Study, C., additional, Aggarwal, R., additional, and Gupta, L., additional

Published
2023
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15. OP0082 COVID-19 VACCINE SAFETY DURING PREGNANCY AND BREASTFEEDING IN WOMEN WITH AUTOIMMUNE DISEASES: RESULTS FROM THE COVAD STUDY

Author

Andreoli, L., primary, Lini, D., additional, Schreiber, K., additional, Sen, P., additional, Ravichandran, N., additional, Parodis, I., additional, Toro Gutierrez, C. E., additional, Katchamart, W., additional, Goo, P. A., additional, Shumnalieva, R., additional, Chibuzo, O. C., additional, Velikova, T., additional, Day, J., additional, Joshi, M., additional, Katsuyuki Shinjo, S., additional, Gracia-Ramos, A. E., additional, Cavagna, L., additional, Kuwana, M., additional, Knitza, J., additional, Makol, A., additional, Chen, Y. M., additional, Study, C., additional, Chinoy, H., additional, Agarwal, V., additional, Aggarwal, R., additional, and Gupta, L., additional

Published
2023
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16. Effect of nintedanib in patients with systemic sclerosis-associated interstitial lung disease and risk factors for rapid decline in forced vital capacity: further analyses of the SENSCIS trial*

Author

Gläser, S, additional, Khanna, D, additional, Maher, T, additional, Volkmann, E, additional, Allanore, Y, additional, Smith, V, additional, Assassi, S, additional, Kreuter, M, additional, Hoffmann-Vold, A, additional, Kuwana, M, additional, Stock, C, additional, Alves, M, additional, Sambevski, S, additional, and Denton, C, additional

Published
2023
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18. Systemic sclerosis and COVID-19 vaccine safety: short-term insights from the global COVID-19 vaccination in autoimmune disease (COVAD) survey

Author

Naveen, R., Thakare, D. R., Kuwana, M., Pauling, J. D., Day, J., Joshi, M., Parodis, I., Sen, P., Jagtap, K., Nikiphorou, E., Saha, S., Agarwal, V., Chatterjee, T., Lilleker, J. B., Kardes, S., Milchert, M., Gheita, T., Salim, B., Velikova, T., Gracia-Ramos, A. E., Tan, A. L., Nune, A., Cavagna, L., Saavedra, M. A., Shinjo, S. K., Ziade, N., Knitza, J., Distler, O., Chinoy, H., Barman, B., Singh, Y. P., Ranjan, R., Jain, A., Pandya, S. C., Pilania, R. K., Sharma, A., Manesh Manoj, M., Gupta, V., Kavadichanda, C. G., Patro, P. S., Ajmani, S., Phatak, S., Goswami, R. P., Chowdhury, A. C., Mathew, A. J., Shenoy, P., Asranna, A., Bommakanti, K. T., Shukla, A., Pande, A. R., Chandwar, K., Cansu, D. U., Wincup, C., Makol, A., Del Papa, N., Sambataro, G., Fabiola, A., Govoni, M., Parisi, S., Bocci, E. B., Sebastiani, G. D., Fusaro, E., Sebastiani, M., Quartuccio, L., Franceschini, F., Sainaghi, P. P., Orsolini, G., De Angelis, R., Danielli, M. G., Venerito, V., Traboco, L. S., Wibowo, S. A. K., Serrano, J. R., La Torre, I. G. -D., Tehozol, E. A. Z., Loarce-Martos, J., Prieto-Gonzalez, S., Gonzalez, R. A., Yoshida, A., Nakashima, R., Sato, S., Kimura, N., Kaneko, Y., Tomaras, S., Gromova, M. A., Aharonov, O., Hmamouchi, I., Hoff, L. S., Giannini, M., Maurier, F., Campagne, J., Meyer, A., Nagy-Vincze, M., Langguth, D., Limaye, V., Needham, M., Srivastav, N., Hudson, M., Landon-Cardinal, O., Shaharir, S. S., Zuleta, W. G. R., Silva, J. A. P., Fonseca, J. E., Zimba, O., Aggarwal, R., and Gupta, L.

Subjects
Adverse events, Autoimmune diseases, Vaccination, COVID-19, Systemic sclerosis
Published
2023

19. Vaccine hesitancy decreases in rheumatic diseases, long-term concerns remain in myositis: a comparative analysis of the COVAD surveys

Author

Sen, P, Naveen, R, Houshmand, N, Kia, Sm, Joshi, M, Saha, S, Jagtap, K, Agarwal, V, Nune, A, Nikiphorou, E, Tan, Al, Shinjo, Sk, Ziade, N, Velikova, T, Milchert, M, Parodis, I, Gracia-Ramos, Ae, Cavagna, L, Kuwana, M, Knitza, J, Makol, A, Patel, A, Pauling, Jd, Wincup, C, Barman, B, Tehozol, Eaz, Serrano, Jr, de la Torre, I, Colunga-Pedraza, Ij, Merayo-Chalico, J, Chibuzo, Oc, Katchamart, W, Goo, Pa, Shumnalieva, R, Chen, Ym, Hoff, Ls, El Kibbi, L, Halabi, H, Vaidya, B, Shaharir, Ss, Hasan, Atmt, Dey, D, Gutierrez, Cet, Caballero-Uribe, Cv, Lilleker, Jb, Salim, B, Gheita, T, Chatterjee, T, Distler, O, Saavedra, Ma, Day, J, Chinoy, H, COVAD Study Grp, Kardes, S, Kardes, Sa, Andreoli, L, Lini, D, Screiber, K, Vince, Mn, Singh, Yp, Ranjan, R, Jain, A, Pandya, Sc, Pilania, Rk, Sharma, A, Manoj, Mm, Gupta, V, Kavadichanda, Cg, Patro, Ps, Ajmani, S, Phatak, S, Goswami, Rp, Chowdhury, Ac, Mathew, Aj, Shenoy, P, Asranna, A, Bommakanti, Kt, Shukla, A, Pande, Ar, Chandwar, K, Ghodke, A, Boro, H, Fazal, Zz, Cansu, Du, Yildirim, R, Gasparyan, Ay, Del Papa, N, Sambataro, G, Fabiola, A, Govoni, M, Parisi, S, Bocci, Eb, Sebastiani, Gd, Fusaro, E, Sebastiani, M, Quartuccio, L, Franceschini, F, Sainaghi, Pp, Orsolini, G, De Angelis, R, Danielli, Mg, Venerito, V, Grignaschi, S, Giollo, A, Alluno, A, Ioannone, F, Fornaro, M, Traboco, Ls, Wibowo, Sak, Loarce-Martos, J, Prieto-Gonzalez, S, Gonzalez, Ra, Yoshida, A, Nakashima, R, Sato, S, Kimura, N, Kaneko, Y, Gono, T, Tomaras, S, Proft, Fn, Holzer, Mt, Gromova, Ma, Aharonov, O, Griger, Z, Hmamouchi, I, El Bouchti, I, Baba, Z, Giannini, M, Maurier, F, Campagne, J, Meyer, A, Langguth, D, Limaye, V, Needham, M, Srivastav, N, Hudson, M, Landon-Cardinal, O, Zuleta, Wgr, Arbelaez, A, Cajas, J, Silva, Jap, Fonseca, Je, Zimba, O, Bohdana, D, Ima-Edomwonyi, U, Dedeke, I, Airenakho, E, Madu, Nh, Yerima, A, Olaosebikan, H, Becky, A, Koussougbo, Od, Palalane, E, So, H, Ugarte-Gil, Mf, Chinchay, L, Bernaola, Jp, Pimentel, V, Fathi, Hm, Mohammed, Rha, Harifi, G, Fuentes-Silva, Y, Cabriza, K, Losanto, J, Colaman, N, Cachafeiro-Vilar, A, Bautista, Gg, Ejg, Ho, Gonzalez, R, Nunez, Ls, Vergara, Mc, Baez, Jt, Alonzo, H, Pastelin, Cbs, Salinas, Rg, Obiols, Aq, Chavez, N, Ordonez, Ab, Argueta, S, Llerena, Gar, Sierra-Zorita, R, Arrieta, D, Hidalgo, Er, Saenz, R, Escalante, Mi, Morales, R, Calapaqui, W, Quezada, I, Arredondo, G, Aggarwal, R, and Gupta, L

Subjects
Rheumatology, idiopathic inflammatory myopathies, COVID-19 vaccines, vaccine hesitancy, registries, Pharmacology (medical), autoimmune disease
Abstract

ObjectiveCOVID-19 vaccines have a favorable safety profile in patients with autoimmune rheumatic diseases (AIRDs) such as idiopathic inflammatory myopathies (IIMs); however, hesitancy continues to persist among these patients. Therefore, we studied the prevalence, predictors and reasons for hesitancy in patients with IIMs, other AIRDs, non-rheumatic autoimmune diseases (nrAIDs) and healthy controls (HCs), using data from the two international COVID-19 Vaccination in Autoimmune Diseases (COVAD) e-surveys.MethodsThe first and second COVAD patient self-reported e-surveys were circulated from March to December 2021, and February to June 2022 (ongoing). We collected data on demographics, comorbidities, COVID-19 infection and vaccination history, reasons for hesitancy, and patient reported outcomes. Predictors of hesitancy were analysed using regression models in different groups.ResultsWe analysed data from 18 882 (COVAD-1) and 7666 (COVAD-2) respondents. Reassuringly, hesitancy decreased from 2021 (16.5%) to 2022 (5.1%) (OR: 0.26; 95% CI: 0.24, 0.30, P ConclusionVaccine hesitancy has decreased from 2021 to 2022, long-term safety concerns remain among patients with IIMs, particularly in Caucasians and those with poor physical function.

Published
2023

20. Poursuite du traitement par le nintédanib chez les patients atteints de sclérodermie systémique cutanée limitée (SCSCL) et de pneumopathie interstitielle diffuse (PID)

Author

Allanore, Y., primary, Khanna, D., additional, Smith, V., additional, Aringer, M., additional, Hoffmann-Vold, A.M., additional, Kuwana, M., additional, Merkel, P.A., additional, James, A., additional, Sambeski, S., additional, Alves, M., additional, and Denton, C.P., additional

Published
2022
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21. Late Skin Fibrosis in Systemic Sclerosis: A Study from the EUSTAR Cohort

Author

Michael Hughes 1 2, Suiyuan Huang 3 4, Juan Jose Alegre-Sancho 5, Patricia E Carreira 6, Merete Engelhart 7, Eric Hachulla 8, Joerg Henes 9, Eduardo Kerzberg 10, Maria Rosa Pozzi 11, Gabriela Riemekasten 12, Vanessa Smith 13, Gabriella Szücs 14, Marie Vanthuyne 15, Elisabetta Zanatta 16, Oliver Distler 17, Armando G Gabrielli 18, Anna-Maria Hoffmann-Vold 19, Virginia D Steen 20, Dinesh Khanna 3 21, EUSTAR Airò P, Allanore A, Ananieva Lp, Anic B, Balbir-Gurman A, Becvar R, Benvenuti F, Cantatore F P, Chung L S, Cuomo G, Cutolo M, Czirják L, Damjanov N, de Vries-Bouwstra J, Del Galdo F, Distler J, Eyerich K, Farge D, Foti R, Gheorghiu A M, Giollo A, Heitmann S, Herrick A, Hesselstrand R, Hsu I M, Hunzelmann N, Iannone F, Iudici M, Ionescuc M R, Ingegnoli F, Jose J, Joven B E, Kerzberg E, Kucharz E J, Kuwana M, Langhe E D, Launay D, Lefebvre P, Litinsky I, García de la Peña Lefebvre P, González-Martín J J, Li M, Loyo E, Martin T, Matucci-Cerinic M, Maurer B, Moroncini G, Mouthon L, Müller Cs, Müller-Ladner U, Novak S, Pastor P, Pecher A-C, Pellerito R, Pozzi M R, Oksel F, Rednic S, Rezus E, Riccieri V, Rosato E, Saketkoo L A, Salvador M J, Schmeiser T, Selmi C F, Sibilia J, Siegert E, Solanki K, Sommerlatte S, Spertini F, Stamenkovic B, Stamp L, Tanaseanu C-M, Tikly M, Tineo C, Ullman S, Üprus M, Vanthuyne M, Veale D, Walker U, Wiland P, Yargucu F, Yavuz S, University of Zurich, Michael Hughes, 1 2, Suiyuan Huang, 3 4, Juan Jose Alegre-Sancho, 5, Patricia, E Carreira 6, Merete Engelhart, 7, Eric Hachulla, 8, Joerg Henes, 9, Eduardo Kerzberg, 10, Maria Rosa Pozzi, 11, Gabriela Riemekasten, 12, Vanessa Smith, 13, Gabriella Szücs, 14, Marie Vanthuyne, 15, Elisabetta Zanatta, 16, Oliver Distler, 17, Armando, G Gabrielli 18, Anna-Maria Hoffmann-Vold, 19, Virginia, D Steen 20, Dinesh Khanna, 3 21, EUSTAR Airò, P, Allanore, A, Ananieva, Lp, Anic, B, Balbir-Gurman, A, Becvar, R, Benvenuti, F, Cantatore, F P, Chung, L S, Cuomo, G, Cutolo, M, Czirják, L, Damjanov, N, de Vries-Bouwstra, J, Del Galdo, F, Distler, J, Eyerich, K, Farge, D, Foti, R, Gheorghiu, A M, Giollo, A, Heitmann, S, Herrick, A, Hesselstrand, R, Hsu, I M, Hunzelmann, N, Iannone, F, Iudici, M, Ionescuc, M R, Ingegnoli, F, Jose, J, Joven, B E, Kerzberg, E, Kucharz, E J, Kuwana, M, Langhe, E D, Launay, D, Lefebvre, P, Litinsky, I, García de la Peña Lefebvre, P, González-Martín, J J, Li, M, Loyo, E, Martin, T, Matucci-Cerinic, M, Maurer, B, Moroncini, G, Mouthon, L, Müller, C, Müller-Ladner, U, Novak, S, Pastor, P, Pecher, A-C, Pellerito, R, Pozzi, M R, Oksel, F, Rednic, S, Rezus, E, Riccieri, V, Rosato, E, Saketkoo, L A, Salvador, M J, Schmeiser, T, Selmi, C F, Sibilia, J, Siegert, E, Solanki, K, Sommerlatte, S, Spertini, F, Stamenkovic, B, Stamp, L, Tanaseanu, C-M, Tikly, M, Tineo, C, Ullman, S, Üprus, M, Vanthuyne, M, Veale, D, Walker, U, Wiland, P, Yargucu, F, and Yavuz, S

Subjects
Rheumatology, Cohort enrichment, 10051 Rheumatology Clinic and Institute of Physical Medicine, Late disease, Systemic sclerosis, Pharmacology (medical), 610 Medicine & health, Fibrosis, Clinical trial design, Scleroderma, Skin
Abstract

Objectives The early trajectory of skin fibrosis provides insights into the disease course of systemic sclerosis (SSc) including mortality; however, little is known about late skin fibrosis. The aims of our study were to ascertain the prevalence and characteristics of late skin fibrosis in SSc. Methods We developed and tested three conceptual scenarios of late (>5 years after first non-RP feature) skin fibrosis including new worsening of skin disease, and failure to improve after worsening within 5-year window. We defined skin worsening as change in modified Rodnan skin score (mRSS) ≥5 units or ≥25%. Using strict inclusion criteria including complete mRSS, we identified 1,043 (out of 19 115) patients within the EUSTAR database for our analysis. We further restricted analysis within 887 (out of 1043) patients who had lcSSc or dcSSc at baseline. Results One-fifth of patients among the whole cohort (n = 208/1043, 19.9%) experienced mRSS worsening, including in patients with lcSSc or dcSSc at baseline (n = 193/887, 21.8%). This was largely due to new skin worsening after the 5-year window or failure to improve with worsening within the 5-year window. Patients with lower baseline mRSS and lcSSc were more likely to develop late skin fibrosis. Anti-Scl-70 was associated with progression from baseline lcSSc to dcSSc, and anticentromere was protective. Conclusions Late skin fibrosis is not uncommon in SSc. We have identified different patterns relevant to clinical practice and trial design. Late skin fibrosis is a neglected manifestation of SSc and warrants further investigation including to determine clinical outcomes and optimal therapeutic strategy.

Published
2022

22. COVID‐19 Vaccination In Autoimmune Diseases (COVAD) Study: Vaccine Safety In Idiopathic Inflammatory Myopathies

Author

Gil‐Vila, A, Naveen, R, Selva‐O'Callaghan, A, Sen, P, Nune, A, Gaur, PS, Gonzalez, RA, Lilleker, JB, Joshi, M, Agarwal, V, Kardes, S, Kim, M, Day, J, Makol, A, Milchert, M, Gheita, T, Salim, B, Velikova, T, Gracia‐Ramos, AE, Parodis, I, Nikiphorou, E, Tan, AL, Chatterjee, T, Cavagna, L, Saavedra, MA, Shinjo, SK, Ziade, N, Knitza, J, Kuwana, M, Distler, O, Chinoy, H, Aggarwal, R, Gupta, L, and COVAD Study Group

Abstract

Introduction/Aims We studied COVID-19 vaccination-related adverse events (ADEs) 7-days post-vaccination in patients with idiopathic inflammatory myopathies (IIMs) and other systemic autoimmune and inflammatory disorders (SAIDs). Methods 7-day vaccine ADEs were collected in an international patient self-reported e-survey. Descriptive statistics and multivariable regression were performed. Results 10,900 respondents [1227 IIMs; 4640 SAIDs; 5033 healthy controls (HCs), median age 42 (IQR 30-55) years, 74% female, 45% Caucasian, 69% completely vaccinated] were analysed. 76.3% IIMs patients reported minor and 4.6% major ADEs. Patients with active IIMs reported more frequent major [OR 2.7 (1.04-7.3)] and minor [OR 1.5 (1.1-2.2)] ADEs than inactive IIMs. Rashes were more frequent in IIMs [OR-2.3(1.2-4.2)] than HCs. ADEs were not impacted by steroid dose, although hydroxychloroquine and intravenous/subcutaneous immunoglobulins were associated with a higher risk of minor ADEs [OR 1.9 (1.1-3.3), OR 2.2 (1.1-4.3)]. Overall, ADEs were less frequent in inclusion body myositis (IBM) and BNT162b2 (Pfizer) vaccine recipients Discussion 7-day post-vaccination ADEs were comparable in patients with IIMs, SAIDs, and HCs, except for a higher risk of rashes in IIMs. Patients with DM, active disease may be at higher risk, and IBM patients at lower risk of specific ADEs. Overall, the benefit of preventing severe COVID-19 through vaccination likely outweighs the risk of vaccine-related ADEs Our results may inform future guidelines regarding COVID-19 vaccination in patients with SAIDs, and specifically in IIMs. Studies to evaluate long-term outcomes and disease flares are needed to shed more light on developing future COVID-19 vaccination guidelines.

Published
2022

23. AB0584 MANAGEMENT OF REFERRALS, TREATMENT STRATEGY, AND RESEARCH CHALLENGES IN POLYMYALGIA RHEUMATICA AMONGST RHEUMATOLOGISTS WORLDWIDE: A QUESTIONNAIRE BASED STUDY

Author

Overgaard Donskov, A., primary, Mackie, S., additional, Hauge, E. M., additional, Toro Gutiérrez, C., additional, Hansen, I., additional, Hemmig, A., additional, Van der Maas, A., additional, Gheita, T. A., additional, Dalsgaard Nielsen, B., additional, Douglas, K., additional, Conway, R., additional, Rezus, E., additional, Dasgupta, B., additional, Monti, S., additional, Matteson, E., additional, Sattui, S. E., additional, Matza, M., additional, Ocampo, V., additional, Bran, A., additional, Appenzeller, S., additional, Goecke, A., additional, Colman MC Leod, N., additional, Keen, H., additional, Kuwana, M., additional, Gupta, L., additional, Salim, B., additional, Harifi, G., additional, Erraoui, M., additional, Ziade, N., additional, Al-Ani, N. A., additional, Ajibade, A., additional, Knitza, J., additional, Frølund, L., additional, Yates, M., additional, Pimentel-Quiroz, V., additional, Lyrio, A., additional, Sandovici, M., additional, Van der Geest, K., additional, Helliwell, T., additional, Brouwer, E., additional, Dejaco, C., additional, and Keller, K., additional

Published
2022
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24. OP0062 EFFICACY AND SAFETY OF ADALIMUMAB WITH LOW AND HIGH DOSE-METHOTREXATE IN PATIENTS WITH RHEUMATOID ARTHRITIS WITH INADEQUATE RESPONSE TO METHOTREXATE: THE RANDOMISED CONTROLLED MIRACLE STUDY

Author

Tamai, H., primary, Ikeda, K., additional, Miyamoto, T., additional, Taguchi, H., additional, Kuo, C. F., additional, Shin, K., additional, Hirata, S., additional, Okano, Y., additional, Sato, S., additional, Yasuoka, H., additional, Choi, I. A., additional, Park, S. H., additional, Weng, M. Y., additional, Kuwana, M., additional, Lee, Y. J., additional, Ishii, T., additional, Kim, J., additional, Kameda, H., additional, Kojima, T., additional, Baek, H. J., additional, Hsu, P. N., additional, Huang, C. M., additional, Cheng, T. T., additional, Sung, W. Y., additional, Taninaga, T., additional, Mori, M., additional, Miyagishi, H., additional, Sato, Y., additional, Takeuchi, T., additional, and Kaneko, Y., additional

Published
2022
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25. OP0112 THE EVER-LARGEST ASIAN GWAS FOR SYSTEMIC SCLEROSIS AND TRANS-POPULATION META-ANALYSIS IDENTIFIED SEVEN NOVEL LOCI AND A CANDIDATE CAUSAL SNP IN A CIS-REGULATORY ELEMENT OF THE FCGR REGION

Author

Ishikawa, Y., primary, Tanaka, N., additional, Asano, Y., additional, Kodera, M., additional, Shirai, Y., additional, Akahoshi, M., additional, Hasegawa, M., additional, Matsushita, T., additional, Kazuyoshi, S., additional, Motegi, S., additional, Yoshifuji, H., additional, Yoshizaki, A., additional, Kohmoto, T., additional, Takagi, K., additional, Oka, A., additional, Kanda, M., additional, Tanaka, Y., additional, Ito, Y., additional, Nakano, K., additional, Kasamatsu, H., additional, Utsunomiya, A., additional, Sekiguchi, A., additional, Niro, H., additional, Jinnin, M., additional, Makino, K., additional, Makino, T., additional, Ihn, H., additional, Yamamoto, M., additional, Suzuki, C., additional, Takahashi, H., additional, Nishida, E., additional, Morita, A., additional, Yamamoto, T., additional, Fujimoto, M., additional, Kondo, Y., additional, Goto, D., additional, Sumida, T., additional, Ayuzawa, N., additional, Yanagida, H., additional, Horita, T., additional, Atsumi, T., additional, Endo, H., additional, Shima, Y., additional, Kumanogoh, A., additional, Hirata, J., additional, Otomo, N., additional, Suetsugu, H., additional, Koike, Y., additional, Tomizuka, K., additional, Yoshino, S., additional, Liu, X., additional, Ito, S., additional, Hikino, K., additional, Suzuki, A., additional, Momozawa, Y., additional, Ikegawa, S., additional, Ishikawa, O., additional, Takehara, K., additional, Torii, T., additional, Sato, S., additional, Okada, Y., additional, Mimori, T., additional, Matsuda, F., additional, Matsuda, K., additional, Imoto, I., additional, Matsuo, K., additional, Kuwana, M., additional, Kawaguchi, Y., additional, Ohmura, K., additional, and Terao, C., additional

Published
2022
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26. OP0161 TREATMENT PATTERNS OF IDIOPATHIC INFLAMMATORY MYOPATHIES: RESULTS FROM AN INTERNATIONAL COHORT OF OVER 1,400 PATIENTS

Author

Aoude, M., primary, Gupta, L., additional, Hmamouchi, I., additional, Grignaschi, S., additional, Cavagna, L., additional, Kim, M., additional, R, N., additional, Lilleker, J. B., additional, Sen, P., additional, Agarwal, V., additional, Kardes, S., additional, Day, J., additional, Makol, A., additional, Milchert, M., additional, Gheita, T. A., additional, Salim, B., additional, Velikova, T., additional, Gracia-Ramos, A. E., additional, Parodis, I., additional, Selva-O’callaghan, A., additional, Nikiphorou, E., additional, Chatterjee, T., additional, Tan, A. L., additional, Saavedra, M. A., additional, Katsuyuki Shinjo, S., additional, Knitza, J., additional, Kuwana, M., additional, Nune, A., additional, Distler, O., additional, Chinoy, H., additional, Aggarwal, R., additional, and Ziade, N., additional

Published
2022
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27. POS0899 HIGH FATIGUE SCORES IN PATIENTS WITH IDIOPATHIC INFLAMMATORY MYOPATHIES: A MULTIGROUP COMPARATIVE STUDY FROM THE COVAD E-SURVEY.

Author

Grignaschi, S., primary, Cavagna, L., additional, Kim, M., additional, R, N., additional, Lilleker, J. B., additional, Sen, P., additional, Agarwal, V., additional, Kardes, S., additional, Day, J., additional, Makol, A., additional, Milchert, M., additional, Gheita, T. A., additional, Salim, B., additional, Velikova, T., additional, Gracia-Ramos, A. E., additional, Parodis, I., additional, Selva-O’callaghan, A., additional, Nikiphorou, E., additional, Chatterjee, T., additional, Tan, A. L., additional, Saavedra, M. A., additional, Katsuyuki Shinjo, S., additional, Ziade, N., additional, Knitza, J., additional, Kuwana, M., additional, Nune, A., additional, Distler, O., additional, Chinoy, H., additional, Aggarwal, R., additional, and Gupta, L., additional

Published
2022
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28. POS0900 SYSTEMIC PHARMACOLOGICAL TREATMENT OF DIGITAL ULCERS IN SYSTEMIC SCLEROSIS: A SYSTEMATIC LITERATURE REVIEW

Author

Maltez, N., primary, Ross, L., additional, Hughes, M., additional, Schoones, J., additional, Baron, M., additional, Chung, L., additional, Campochiaro, C., additional, Suliman, Y. A., additional, Giuggioli, D., additional, Moinzadeh, P., additional, Allanore, Y., additional, Denton, C. P., additional, Distler, O., additional, Frech, T., additional, Furst, D., additional, Khanna, D., additional, Krieg, T., additional, Kuwana, M., additional, Matucci-Cerinic, M., additional, Pope, J., additional, and Alunno, A., additional

Published
2022
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29. POS0201 COVID-19 SEVERITY AND VACCINE BREAKTHROUGH INFECTIONS IN IDIOPATHIC INFLAMMATORY MYOPATHIES, OTHER SYSTEMIC AUTOIMMUNE AND INFLAMMATORY DISEASES, AND HEALTHY INDIVIDUALS: RESULTS FROM THE COVID-19 VACCINATION IN AUTOIMMUNE DISEASES (COVAD) STUDY.

Author

Gupta, L., primary, Hoff, L. S., additional, R, N., additional, Sen, P., additional, Katsuyuki Shinjo, S., additional, Day, J., additional, Lilleker, J. B., additional, Agarwal, V., additional, Kardes, S., additional, Kim, M., additional, Makol, A., additional, Milchert, M., additional, Gheita, T. A., additional, Salim, B., additional, Velikova, T., additional, Gracia-Ramos, A. E., additional, Parodis, I., additional, Selva-O’callaghan, A., additional, Nikiphorou, E., additional, Chatterjee, T., additional, Tan, A. L., additional, Nune, A., additional, Cavagna, L., additional, Saavedra, M. A., additional, Ziade, N., additional, Knitza, J., additional, Kuwana, M., additional, Distler, O., additional, Chinoy, H., additional, and Aggarwal, R., additional

Published
2022
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30. POS0066 THE PHENOTYPE OF MIXED CONNECTIVE TISSUE DISEASE PATIENTS HAVING ASSOCIATED INTERSTITIAL LUNG DISEASE

Author

Boleto, G., primary, Reiseter, S., additional, Hoffmann-Vold, A. M., additional, Mirouse, A., additional, Cacoub, P., additional, Matucci-Cerinic, M., additional, Silvério-António, M., additional, Fonseca, J. E., additional, Riccieri, V., additional, Le Tallec, E., additional, Lescoat, A., additional, Tandaipan, J. L., additional, Castellví, I., additional, Airò, P., additional, Kuwana, M., additional, Kavosi, H., additional, Avouac, J., additional, and Allanore, Y., additional

Published
2022
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31. POS0855 IMPAIRED PROMIS PHYSICAL FUNCTION IN IDIOPATHIC INFLAMMATORY MYOPATHY PATIENTS: RESULTS FROM THE MULTICENTER COVAD PATIENT REPORTED E-SURVEY

Author

Yoshida, A., primary, Kim, M., additional, Kuwana, M., additional, R, N., additional, Lilleker, J. B., additional, Sen, P., additional, Agarwal, V., additional, Kardes, S., additional, Day, J., additional, Makol, A., additional, Milchert, M., additional, Gheita, T. A., additional, Salim, B., additional, Velikova, T., additional, Gracia-Ramos, A. E., additional, Parodis, I., additional, Selva-O’callaghan, A., additional, Nikiphorou, E., additional, Chatterjee, T., additional, Tan, A. L., additional, Nune, A., additional, Cavagna, L., additional, Saavedra, M. A., additional, Katsuyuki Shinjo, S., additional, Ziade, N., additional, Knitza, J., additional, Distler, O., additional, Chinoy, H., additional, Aggarwal, R., additional, and Gupta, L., additional

Published
2022
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32. OP0157 EFFECT OF NINTEDANIB IN PATIENTS WITH SYSTEMIC SCLEROSIS-ASSOCIATED INTERSTITIAL LUNG DISEASE (SSc-ILD) AND RISK FACTORS FOR RAPID DECLINE IN FORCED VITAL CAPACITY: FURTHER ANALYSES OF THE SENSCIS TRIAL

Author

Khanna, D., primary, Maher, T., additional, Volkmann, E., additional, Allanore, Y., additional, Smith, V., additional, Assassi, S., additional, Kreuter, M., additional, Hoffmann-Vold, A. M., additional, Kuwana, M., additional, Stock, C., additional, Alves, M., additional, Sambevski, S., additional, and Denton, C. P., additional

Published
2022
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34. POS0898 SURGICAL MANAGEMENT OF DIGITAL ULCERS IN SYSTEMIC SCLEROSIS: A SYSTEMATIC LITERATURE REVIEW.

Author

Suliman, Y. A., primary, Campochiaro, C., additional, Hughes, M., additional, Schoones, J., additional, Giuggioli, D., additional, Maltez, N., additional, Moinzadeh, P., additional, Ross, L., additional, Chung, L., additional, Allanore, Y., additional, Baron, M., additional, Denton, C. P., additional, Distler, O., additional, Frech, T., additional, Furst, D., additional, Khanna, D., additional, Krieg, T., additional, Kuwana, M., additional, Matucci-Cerinic, M., additional, Pope, J., additional, and Alunno, A., additional

Published
2022
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35. POS1260 COVID-19 VACCINATION-RELATED ADVERSE EVENTS AMONG AUTOIMMUNE DISEASE PATIENTS: RESULTS FROM THE COVID-19 VACCINATION IN AUTOIMMUNE DISEASES (COVAD) STUDY

Author

Sen, P., primary, R, N., additional, Nune, A., additional, Lilleker, J. B., additional, Agarwal, V., additional, Kardes, S., additional, Kim, M., additional, Day, J., additional, Milchert, M., additional, Gheita, T. A., additional, Salim, B., additional, Velikova, T., additional, Gracia-Ramos, A. E., additional, Parodis, I., additional, Selva-O’callaghan, A., additional, Nikiphorou, E., additional, Chatterjee, T., additional, Tan, A. L., additional, Cavagna, L., additional, Saavedra, M. A., additional, Katsuyuki Shinjo, S., additional, Ziade, N., additional, Knitza, J., additional, Kuwana, M., additional, Distler, O., additional, Chinoy, H., additional, Aggarwal, R., additional, and Gupta, L., additional

Published
2022
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36. POS0888 NON-SURGICAL LOCAL TREATMENTS FOR DIGITAL ULCERS IN SYSTEMIC SCLEROSIS: A SYSTEMATIC LITERATURE REVIEW

Author

Campochiaro, C., primary, Suliman, Y. A., additional, Hughes, M., additional, Schoones, J., additional, Giuggioli, D., additional, Moinzadeh, P., additional, Maltez, N., additional, Ross, L., additional, Baron, M., additional, Chung, L., additional, Allanore, Y., additional, Denton, C. P., additional, Distler, O., additional, Frech, T., additional, Furst, D., additional, Khanna, D., additional, Krieg, T., additional, Kuwana, M., additional, Matucci-Cerinic, M., additional, Pope, J., additional, and Alunno, A., additional

Published
2022
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38. Factors Prognostic of Greater Decline in Forced Vital Capacity in Patients with Systemic Sclerosis-Associated Interstitial Lung Disease (SSc-ILD): Data from the Placebo Group of the SENSCIS Trial*

Author

Prasse, A, additional, Kuwana, M, additional, Assassi, S, additional, Avouac, J, additional, Hoyles, R K, additional, Pope, J, additional, Smith, V, additional, Miede, C, additional, Clerisme-Beaty, E, additional, Alves, M, additional, and Distler, O, additional

Published
2022
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39. Dry Eye Associated with Chronic Graft-Versus-Host Disease

Author

Ogawa, Y., Kuwana, M., Yamazaki, K., Mashima, Y., Okamoto, S., Tsubota, K., Oguchi, Y., Kawakami, Y., Sullivan, David A., editor, Stern, Michael E., editor, Tsubota, Kazuo, editor, Dartt, Darlene A., editor, Sullivan, Rose M., editor, and Bromberg, B. Britt, editor

Published
2002
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43. EFFECTIVENESS AND SAFETY OF TOCILIZUMAB IN PATIENTS WITH SYSTEMIC SCLEROSIS: A PROPENSITY SCORE CONTROL MATCHED OBSERVATIONAL STUDY OF THE EUSTAR COHORT

Author

Kuster S, Jordan S, Elhai M, Held U, Steigmiller K, Bruni C, Iannone F, Vettori S, Siegert E, Rednic S, Codullo V, Airo P, Braun-Moscovici Y, Hunzelmann N, Salvador M, Riccieri V, Gheorghiu A, Sancho J, Romanowska-Prochnicka K, Castellvi I, Koetter I, Truchetet M, Lopez-Longo F, Novikov P, Giollo A, Shirai Y, Belloli L, Zanatta E, Hachulla E, Smith V, Denton C, Ionescu R, Schmeiser T, Distler J, Gabrielli A, Hoffmann-Vold A, Kuwana M, Allanore Y, Distler O, and EUSTAR

Published
2021

44. Primary systemic sclerosis heart involvement: A systematic literature review and preliminary data-driven, consensus-based WSF/HFA definition

Author

Bruni, C. Buch, M.H. Furst, D.E. De Luca, G. Djokovic, A. Dumitru, R.B. Giollo, A. Polovina, M. Steelandt, A. Bratis, K. Suliman, Y.A. Milinkovic, I. Baritussio, A. Hasan, G. Xintarakou, A. Isomura, Y. Markousis-Mavrogenis, G. Tofani, L. Mavrogeni, S. Gargani, L. Caforio, A.L.P. Tschöpe, C. Ristic, A. Klingel, K. Plein, S. Behr, E.R. Allanore, Y. Kuwana, M. Denton, C.P. Khanna, D. Krieg, T. Marcolongo, R. Galetti, I. Zanatta, E. Tona, F. Seferovic, P. Matucci-Cerinic, M.

Abstract

Introduction: Primary heart involvement in systemic sclerosis may cause morpho-functional and electrical cardiac abnormalities and is a common cause of death. The absence of a clear definition of primary heart involvement in systemic sclerosis limits our understanding and ability to focus on clinical research. We aimed to create an expert consensus definition for primary heart involvement in systemic sclerosis. Methods: A systematic literature review of cardiac involvement and manifestations in systemic sclerosis was conducted to inform an international and multi-disciplinary task force. In addition, the nominal group technique was used to derive a definition that was then subject to voting. A total of 16 clinical cases were evaluated to test face validity, feasibility, reliability and criterion validity of the newly created definition. Results: In total, 171 publications met eligibility criteria. Using the nominal group technique, experts added their opinion, provided statements to consider and ranked them to create the consensus definition, which received 100% agreement on face validity. A median 60(5–300) seconds was taken for the feasibility on a single case. Inter-rater agreement was moderate (mKappa (95% CI) = 0.56 (0.46–1.00) for the first round and 0.55 (0.44–1.00) for the second round) and intra-rater agreement was good (mKappa (95% CI) = 0.77 (0.47–1.00)). Criterion validity showed a 78 (73–84)% correctness versus gold standard. Conclusion: A preliminary primary heart involvement in systemic sclerosis consensus-based definition was created and partially validated, for use in future clinical research. © The Author(s) 2021.

Published
2021

45. AB0249 SAFETY OF BARICITINIB IN JAPANESE PATIENTS WITH RHEUMATOID ARTHRITIS (RA): THE 2020 INTERIM REPORT FROM ALL-CASE POST MARKETING SURVEILLANCE IN CLINICAL PRACTICE

Author

Fujii, T., primary, Atsumi, T., additional, Okamoto, N., additional, Takahashi, N., additional, Tamura, N., additional, Nakajima, A., additional, Matsuno, H., additional, Tsujimoto, N., additional, Nishikawa, A., additional, Ishii, T., additional, Takeuchi, T., additional, Kuwana, M., additional, and Takagi, M., additional

Published
2021
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46. POS0861 EFFECTIVENESS AND SAFETY OF TOCILIZUMAB IN PATIENTS WITH SYSTEMIC SCLEROSIS: A PROPENSITY SCORE CONTROL MATCHED OBSERVATIONAL STUDY OF THE EUSTAR COHORT

Author

Kuster, S., primary, Jordan, S., additional, Elhai, M. D., additional, Held, U., additional, Steigmiller, K., additional, Bruni, C., additional, Iannone, F., additional, Vettori, S., additional, Siegert, E., additional, Rednic, S., additional, Codullo, V., additional, Airò, P., additional, Braun-Moscovici, Y., additional, Hunzelmann, N., additional, Salvador, M. J., additional, Riccieri, V., additional, Gheorghiu, A. M., additional, Alegre Sancho, J. J., additional, Romanowska-Prochnicka, K., additional, Castellví, I., additional, Koetter, I., additional, Truchetet, M. E., additional, López-Longo, F. J., additional, Novikov, P., additional, Giollo, A., additional, Shirai, Y., additional, Belloli, L., additional, Zanatta, E., additional, Hachulla, E., additional, Smith, V., additional, Denton, C., additional, Ionescu, R., additional, Schmeiser, T., additional, Distler, J. H. W., additional, Gabrielli, A., additional, Hoffmann-Vold, A. M., additional, Kuwana, M., additional, Allanore, Y., additional, and Distler, O., additional

Published
2021
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47. AB0253 COMPARISON OF PHARMACODYNAMICS OF METHOTREXATE AS METHOTREXATE-POLYGLUTAMATES CONCENTRATIONS IN RHEUMATOID ARTHRITIS; INTERIM DATA EVALUATION OF MIRACLE STUDY CONDUCTED IN JAPAN, KOREA AND TAIWAN

Author

Tamai, H., primary, Kaneko, Y., additional, Kameda, H., additional, Kuwana, M., additional, Okano, Y., additional, Ishii, T., additional, Ikeda, K., additional, Taguchi, H., additional, Sato, S., additional, Miyamoto, T., additional, Hirata, S., additional, Yasuoka, H., additional, Kojima, T., additional, Park, S. H., additional, Shin, K., additional, Baek, H. J., additional, Lee, Y. J., additional, Choi, I. A., additional, Kim, J., additional, Hsu, P. N., additional, Kuo, C. F., additional, Huang, C. M., additional, Weng, M. Y., additional, Sung, W. Y., additional, Tsai, W. C., additional, Cheng, T. T., additional, Taninaga, T., additional, Mori, M., additional, Miyagishi, H., additional, Sato, Y., additional, and Takeuchi, T., additional

Published
2021
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49. OP0171 PHASE 3 TRIAL OF LENABASUM, A CB2 AGONIST, FOR THE TREATMENT OF DIFFUSE CUTANEOUS SYSTEMIC SCLEROSIS (DCSSC)

Author

Spiera, R., primary, Kuwana, M., additional, Khanna, D., additional, Hummers, L., additional, Frech, T., additional, Stevens, W., additional, Gordon, J., additional, Kafaja, S., additional, Matucci-Cerinic, M., additional, Distler, O., additional, Lee, E. B., additional, Levy, Y., additional, Jun, J. B., additional, Constantine, S., additional, Dgetluck, N., additional, White, B., additional, Furst, D., additional, and Denton, C., additional

Published
2021
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50. POS1228 THE ROLE OF CHEST CT IN UNDERSTANDING INTERSTITIAL LUNG DISEASE (ILD): SYSTEMIC SCLEROSIS (SSc). VERSUS COVID-19

Author

Orlandi, M., primary, Landini, N., additional, Sambataro, G., additional, Nardi, C., additional, Bruni, C., additional, Bellando-Randone, S., additional, Denton, C., additional, Luppi, F., additional, Ruaro, B., additional, Tomassetti, S., additional, Cavigli, E., additional, Melchiorre, F., additional, Palmucci, S., additional, Guiducci, S., additional, Moggi Pignone, A., additional, Allanore, Y., additional, Bartoloni, A., additional, Confalonieri, M., additional, Cortese, G., additional, Dagna, L., additional, De Cobelli, F., additional, De Paulis, A., additional, Harari, S., additional, Khanna, D., additional, Kuwana, M., additional, Miele, V., additional, Taliani, G., additional, Hughes, M., additional, Vanchieri, C., additional, Colagrande, S., additional, and Matucci-Cerinic, M., additional

Published
2021
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