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20 results on '"Kusama, Taishi"'

11. Prenylated Benzophenones from Triadenum japonicum

Author

Oya, Atsushi, primary, Tanaka, Naonobu, additional, Kusama, Taishi, additional, Kim, Sang-Yong, additional, Hayashi, Shigeki, additional, Kojoma, Mareshige, additional, Hishida, Atsuyuki, additional, Kawahara, Nobuo, additional, Sakai, Kanae, additional, Gonoi, Tohru, additional, and Kobayashi, Jun’ichi, additional

Published
2015
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19. Agelamadins C–E, Bromopyrrole Alkaloids ComprisingOroidin and 3-Hydroxykynurenine from a Marine Sponge Agelassp.

Author

Kusama, Taishi, Tanaka, Naonobu, Sakai, Kanae, Gonoi, Tohru, Fromont, Jane, Kashiwada, Yoshiki, and Kobayashi, Jun’ichi

Subjects
*ALKALOIDS, *KYNURENINE, *OXAZINES, *ANTI-infective agents, *SPECTRUM analysis, *DEMOSPONGIAE
Abstract

Three structurallyunique bromopyrrole alkaloids, agelamadins C–E(1–3), were isolated from a marinesponge Agelassp. Agelamadin C (1) possesses a hybrid structure of oroidin and 3-hydroxykynurenineconnected through a dihydro-1,4-oxazine moiety. Agelamadins D (2) and E (3) are a C-9/C-10 diastereomer anda 10-epimer of 1, respectively. The structures of 1–3were elucidated on the basis of spectroscopicanalysis as well as application of a PGME method and a TDDFT ECD calculation.Antimicrobial activity of 1–3wasevaluated. [ABSTRACT FROM AUTHOR]

Published
2014
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20. Agelamadins A and B, Dimeric Bromopyrrole Alkaloidsfrom a Marine Sponge Agelassp.

Author

Kusama, Taishi, Tanaka, Naonobu, Sakai, Kanae, Gonoi, Tohru, Fromont, Jane, Kashiwada, Yoshiki, and Kobayashi, Jun’ichi

Subjects
*PYRROLES, *ALKALOIDS, *SPONGES (Invertebrates), *MOIETIES (Chemistry), *ANTI-infective agents, *SPECTRUM analysis
Abstract

Twostructurally unique dimeric bromopyrrole alkaloids, agelamadinsA (1) and B (2), were isolated from a marinesponge Agelassp. Agelamadins A (1)and B (2) have a structure consisting of an agelastatin-liketetracyclic moiety and an oroidin-like linear moiety in common. Thestructures of 1and 2were elucidated onthe basis of spectroscopic analysis. The antimicrobial activity andcytotoxicity of agelamadins A (1) and B (2) were evaluated. [ABSTRACT FROM AUTHOR]

Published
2014
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