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3. Global Practice Patterns in the Evaluation of Non-Obstructive Azoospermia: Results of a World-Wide Survey and Expert Recommendations

Author

Shah, Rupin, primary, Rambhatla, Amarnath, additional, Atmoko, Widi, additional, Martinez, Marlon, additional, Ziouziou, Imad, additional, Kothari, Priyank, additional, Tadros, Nicholas, additional, Phuoc, Nguyen Ho Vinh, additional, Kavoussi, Parviz, additional, Harraz, Ahmed, additional, Salvio, Gianmaria, additional, Gul, Murat, additional, Hamoda, Taha, additional, Toprak, Tuncay, additional, Birowo, Ponco, additional, Ko, Edmund, additional, Arafa, Mohamed, additional, Ghayda, Ramy Abou, additional, Karthikeyan, Vilvapathy Senguttuvan, additional, Saleh, Ramadan, additional, Russo, Giorgio Ivan, additional, Pinggera, Germar-Michael, additional, Chung, Eric, additional, Savira, Missy, additional, Colpi, Giovanni M., additional, Zohdy, Wael, additional, Pescatori, Edoardo, additional, Park, Hyun Jun, additional, Fukuhara, Shinichiro, additional, Tsujimura, Akira, additional, Rojas-Cruz, Cesar, additional, Marino, Angelo, additional, Mak, Siu King, additional, Amar, Edouard, additional, Ibrahim, Wael, additional, Sindhwani, Puneet, additional, Alhathal, Naif, additional, Busetto, Gian Maria, additional, Hashimi, Manaf Al, additional, El-Sakka, Ahmed, additional, Ramazan, Asci, additional, Dimitriadis, Fotios, additional, Timpano, Massimiliano, additional, Jezek, Davor, additional, Altay, Baris, additional, Zylbersztejn, Daniel Suslik, additional, Wong, Michael YC, additional, Moon, Du Geon, additional, Wyns, Christine, additional, Gamidov, Safar, additional, Akhavizadegan, Hamed, additional, Franceschelli, Alessandro, additional, Aydos, Kaan, additional, Quang, Vinh Nguyen, additional, Ashour, Shedeed, additional, Dayel, Adel Al, additional, Al-Marhoon, Mohamed S., additional, Micic, Sava, additional, Binsaleh, Saleh, additional, Hussein, Alayman, additional, Elbardisi, Haitham, additional, Mostafa, Taymour, additional, Taha, Emad, additional, Ramsay, Jonathan, additional, Zachariou, Athanasios, additional, Abdelrahman, Islam Fathy Soliman, additional, Rajmil, Osvaldo, additional, Kalkanli, Arif, additional, Molina, Juan Manuel Corral, additional, Bocu, Kadir, additional, Duarsa, Gede Wirya Kusuma, additional, Ceker, Gokhan, additional, Serefoglu, Ege Can, additional, Bahar, Fahmi, additional, Gherabi, Nazim, additional, Kuroda, Shinnosuke, additional, Bouzouita, Abderrazak, additional, Gudeloglu, Ahmet, additional, Ceyhan, Erman, additional, Hasan, Mohamed Saeed Mohamed, additional, Musa, Muhammad Ujudud, additional, Motawi, Ahmad, additional, Chak-Lam, Cho, additional, Taniguchi, Hisanori, additional, Ho, Christopher Chee Kong, additional, Vazquez, Jesus Fernando Solorzano, additional, Mutambirwa, Shingai, additional, Gungor, Nur Dokuzeylul, additional, Bendayan, Marion, additional, Giulioni, Carlo, additional, Baser, Aykut, additional, Falcone, Marco, additional, Boeri, Luca, additional, Blecher, Gideon, additional, Kheradmand, Alireza, additional, Sethupathy, Tamilselvi, additional, Adriansjah, Ricky, additional, Narimani, Nima, additional, Konstantinidis, Charalampos, additional, Nguyen, Tuan Thanh, additional, Japari, Andrian, additional, Dolati, Parisa, additional, Singh, Keerti, additional, Ozer, Cevahir, additional, Sarikaya, Selcuk, additional, Sheibak, Nadia, additional, Bosco, Ndagijimana Jean, additional, Özkent, Mehmet Serkan, additional, Le, Sang Thanh, additional, Sokolakis, Ioannis, additional, Katz, Darren, additional, Smith, Ryan, additional, Truong, Manh Nguyen, additional, Le, Tan V., additional, Huang, Zhongwei, additional, Deger, Muslim Dogan, additional, Arslan, Umut, additional, Calik, Gokhan, additional, Franco, Giorgio, additional, Rashed, Ayman, additional, Kahraman, Oguzhan, additional, Andreadakis, Sotiris, additional, Putra, Rosadi, additional, Balercia, Giancarlo, additional, Khalafalla, Kareim, additional, Cannarella, Rossella, additional, Tuấn, Anh Đặng, additional, Meliegy, Amr El, additional, Zilaitiene, Birute, additional, Ramirez, Marlene Lizbeth Zamora, additional, Giacone, Filippo, additional, Calogero, Aldo E., additional, Makarounis, Konstantinos, additional, Jindal, Sunil, additional, Hoai, Bac Nguyen, additional, Banthia, Ravi, additional, Peña, Marcelo Rodriguez, additional, Moorthy, Dharani, additional, Adamyan, Aram, additional, Kulaksiz, Deniz, additional, Kandil, Hussein, additional, Sofikitis, Nikolaos, additional, Salzano, Ciro, additional, Jungwirth, Andreas, additional, Banka, Surendra Reddy, additional, Mierzwa, Tiago Cesar, additional, Turunç, Tahsin, additional, Jain, Divyanu, additional, Avoyan, Armen, additional, Salacone, Pietro, additional, Kadıoğlu, Ateş, additional, Gupta, Chirag, additional, Lin, Haocheng, additional, Shamohammadi, Iman, additional, Mogharabian, Nasser, additional, Barrett, Trenton, additional, Danacıoğlu, Yavuz Onur, additional, Crafa, Andrea, additional, Daoud, Salima, additional, Malhotra, Vineet, additional, Almardawi, Abdulmalik, additional, Selim, Osama Mohamed, additional, Moussa, Mohamad, additional, Haghdani, Saeid, additional, Duran, Mesut Berkan, additional, Kunz, Yannic, additional, Preto, Mirko, additional, Eugeni, Elena, additional, Nguyen, Thang, additional, Elshahid, Ahmed Rashad, additional, Suyono, Seso Sulijaya, additional, Parikesit, Dyandra, additional, Nada, Essam, additional, Orozco, Eduardo Gutiérrez, additional, Boitrelle, Florence, additional, Trang, Nguyen Thi Minh, additional, Jamali, Mounir, additional, Nair, Raju, additional, Ruzaev, Mikhail, additional, Gadda, Franco, additional, Thomas, Charalampos, additional, Ferreira, Raphael Henrique, additional, Gul, Umit, additional, Maruccia, Serena, additional, Kanbur, Ajay, additional, Kinzikeeva, Ella, additional, Abumelha, Saad, additional, Quang, Nguyen, additional, Kosgi, Raghavender, additional, Gokalp, Fatih, additional, Soebadi, Mohammad Ayodhia, additional, Paul, Gustavo Marquesine, additional, Sajadi, Hesamoddin, additional, Gupte, Deepak, additional, Ambar, Rafael F., additional, Sogutdelen, Emrullah, additional, Singla, Karun, additional, Basurkano, Ari, additional, Kim, Shannon Hee Kyung, additional, Gilani, Mohammad Ali Sadighi, additional, Nagao, Koichi, additional, Brodjonegoro, Sakti Ronggowardhana, additional, Rezano, Andri, additional, Elkhouly, Mohamed, additional, Mazzilli, Rossella, additional, Farsi, Hasan M. A., additional, Ba, Hung Nguyen, additional, Alali, Hamed, additional, Kafetzis, Dimitrios, additional, Long, Tran Quang Tien, additional, Alsaid, Sami, additional, Cuong, Hoang Bao Ngoc, additional, Oleksandr, Knigavko, additional, Mustafa, Akhmad, additional, Acosta, Herik, additional, Pai, Hrishikesh, additional, Şahin, Bahadır, additional, Arianto, Eko, additional, Teo, Colin, additional, Jayaprakash, Sanjay Prakash, additional, Rachman, Rinaldo Indra, additional, Yenice, Mustafa Gurkan, additional, Sefrioui, Omar, additional, Paghdar, Smit, additional, Priyadarshi, Shivam, additional, Tanic, Marko, additional, Alfatlawy, Noor Kareem, additional, Rizaldi, Fikri, additional, Vishwakarma, Ranjit B., additional, Kanakis, George, additional, Cherian, Dinesh Thomas, additional, Lee, Joe, additional, Galstyan, Raisa, additional, Keskin, Hakan, additional, Wurzacher, Jana, additional, Seno, Doddy Hami, additional, Noegroho, Bambang S., additional, Margiana, Ria, additional, Javed, Qaisar, additional, Castiglioni, Fabrizio, additional, Tanwar, Raman, additional, Puigvert, Ana, additional, Kaya, Coşkun, additional, Purnomo, Medianto, additional, Yazbeck, Chadi, additional, Amir, Azwar, additional, Borges, Edson, additional, Bellavia, Marina, additional, Deswanto, Isaac Ardianson, additional, V, Vinod K, additional, Liguori, Giovanni, additional, Minh, Dang Hoang, additional, Siddiqi, Kashif, additional, Colombo, Fulvio, additional, Zini, Armand, additional, Patel, Niket, additional, Çayan, Selahittin, additional, Al-Kawaz, Ula, additional, Ragab, Maged, additional, Hebrard, Guadalupe Hernández, additional, Hoffmann, Ivan, additional, Efesoy, Ozan, additional, Saylam, Barış, additional, and Agarwal, Ashok, additional

Published
2024
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4. Antioxidants for male infertility: therapeutic scheme and indications. A retrospective single-center real-life study

Author

CANNARELLA, Rossella, primary, CRAFA, Andrea, additional, SAWAID KAIYAL, Raneen, additional, KURODA, Shinnosuke, additional, BARBAGALLO, Federica, additional, ALAMO, Angela, additional, MONGIOÌ, Laura M., additional, SAPIENZA, Sabrina, additional, CONDORELLI, Rosita A., additional, LA VIGNERA, Sandro, additional, and CALOGERO, Aldo E., additional

Published
2024
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8. Clinical management of nonobstructive azoospermia: An update.

Author

Takeshima, Teppei, Karibe, Jurii, Saito, Tomoki, Kuroda, Shinnosuke, Komeya, Mitsuru, Uemura, Hiroji, and Yumura, Yasushi

Subjects
AZOOSPERMIA, MALE infertility, SPERM donation, ARTIFICIAL insemination, ORGAN culture, KALLMANN syndrome, FREEDOM of information
Abstract

Approximately 1% of the general male population has azoospermia, and nonobstructive azoospermia accounts for the majority of cases. The causes vary widely, including chromosomal and genetic abnormalities, varicocele, drug‐induced causes, and gonadotropin deficiency; however, the cause is often unknown. In azoospermia caused by hypogonadotropic hypogonadism, gonadotropin replacement therapy can be expected to produce sperm in the ejaculate. In some cases, upfront varicocelectomy for nonobstructive azoospermia with varicocele may result in the appearance of ejaculated spermatozoa; however, the appropriate indication should be selected. Each guideline recommends microdissection testicular sperm extraction for nonobstructive azoospermia in terms of successful sperm retrieval and avoidance of complications. Sperm retrieval rates generally ranged from 20% to 70% but vary depending on the causative disease. Various attempts have been made to predict sperm retrieval and improve sperm retrieval rates; however, the evidence is insufficient. Further evidence accumulation is needed for salvage treatment in cases of failed sperm retrieval. In Japan, there is inadequate provision on the right to know the origin of children born from artificial insemination of donated sperm and the rights of sperm donors, as well as information on unrelated family members, and the development of these systems is challenging. In the future, it is hoped that the pathogenesis of nonobstructive azoospermia with an unknown cause will be elucidated and that technology for omics technologies, human spermatogenesis using pluripotent cells, and organ culture methods will be developed. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Antioxidants for male infertility: therapeutic scheme and indications. A retrospective single-center real-life study

Author

Cannarella, Rossella, primary, Crafa, Andrea, additional, Kaiyal, Raneen Sawaid, additional, Kuroda, Shinnosuke, additional, Barbagallo, Federica, additional, Alamo, Angela, additional, Mongioì, Laura M., additional, Sapienza, Sabrina, additional, Condorelli, Rosita A., additional, Vignera, Sandro La, additional, and Calogero, Aldo E., additional

Published
2023
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17. Novel sperm chromatin dispersion test with artificial intelligence‐aided halo evaluation: A comparison study with existing modalities.

Author

Kuroda, Shinnosuke, Karna, Keshab Kumar, Kaiyal, Raneen Sawaid, Cannarella, Rossella, Lundy, Scott D., Vij, Sarah C., and Agarwal, Ashok

Subjects
*SPERMATOZOA, *CHROMATIN, *DISPERSION (Chemistry), *MALE infertility, *BLAND-Altman plot
Abstract

Background: Sperm chromatin dispersion test is a common and inexpensive technique to assess sperm DNA fragmentation, but its subjectivity in assessing a small number of spermatozoa is a disadvantage. Objectives: To study the efficacy of a new sperm chromatin dispersion test kit (R10) combined with an artificial intelligence‐aided halo‐evaluation platform (X12) and compare the results to those of existing sperm DNA fragmentation testing methods. Materials and methods: Semen samples from normozoospermic donors (n = 10) and infertile men with abnormal semen parameters (n = 10) were enrolled. DNA fragmentation indices were examined by multiple assays, including R10, Halosperm G2 (G2), sperm chromatin structure assay, and terminal deoxynucleotidyl transferase deoxynucleotidyl transferase nick end labeling. In R10 assay, the DNA fragmentation indices were obtained both manually (manual R10) and by X12 (AI‐R10). The obtained DNA fragmentation indices were analyzed by agreement analyses. Results: The DNA fragmentation indices obtained by manual R10 and those obtained by AI‐R10 showed a strong significant correlation (r = 0.97, p < 0.001) and agreement. The number of spermatozoa evaluated by AI‐R10 was 2078 (680–5831). The DNA fragmentation indices obtained by manual R10 and AI‐R10 both correlated with those of G2 (r = 0.90, p < 0.001; r = 0.88, p < 0.001). Between the AI‐R10 and G2 results, Passing–Bablok regression showed no systematic or proportional difference, and Bland–Altman plots revealed overall agreement and a mean bias of 6.3% with an SD of 6.9% (95% limit of agreement: −7.2% to 19.9%). AI‐R10 and sperm chromatin structure assays showed systematic differences with a mean bias of −1.9%, while AI‐R10 and terminal deoxynucleotidyl transferase deoxynucleotidyl transferase nick end labeling revealed proportional differences with a mean bias of −10.7%. Conclusions: The novel sperm chromatin dispersion kit and artificial intelligence‐aided platform demonstrated significant correlation and agreement with existing sperm chromatin dispersion methods by assessing greater number of spermatozoa. This technique has the potential to provide a rapid and accurate assessment of sperm DNA fragmentation without technical expertise or flow cytometry. [ABSTRACT FROM AUTHOR]

Published
2023
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19. Time-dependent change in relapse sites of renal cell carcinoma after curative surgery

Author

Noguchi, Go, Nakaigawa, Noboru, Taguri, Masataka, Tsutsumi, Sohgo, Saito, Yoko, Fukui, Sachi, Yasui, Masato, Tokita, Takashi, Mitome, Taku, Tatenuma, Tomoyuki, Kuroda, Shinnosuke, Abe, Koichi, Ueno, Daiki, Namura, Kazuhiro, Umemoto, Susumu, Takizawa, Akitoshi, Ohta, Junichi, Ueki, Teiichiro, Watanabe, Takeshi, Kobayashi, Kazuki, Kondo, Keiichi, Kishida, Takeshi, Kanno, Hitomi, Kitami, Kazuo, Yamanaka, Takeharu, and Yao, Masahiro

Published
2018
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20. Impact of Antioxidant Therapy on Natural Pregnancy Outcomes and Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Author

Agarwal, Ashok, primary, Cannarella, Rossella, additional, Saleh, Ramadan, additional, Harraz, Ahmed M., additional, Kandil, Hussein, additional, Salvio, Gianmaria, additional, Boitrelle, Florence, additional, Kuroda, Shinnosuke, additional, Farkouh, Ala’a, additional, Rambhatla, Amarnath, additional, Zini, Armand, additional, Colpi, Giovanni, additional, Gül, Murat, additional, Kavoussi, Parviz, additional, Hamoda, Taha Abo-Almagd Abdel-Meguid, additional, Ko, Edmund, additional, Calik, Gokhan, additional, Toprak, Tuncay, additional, Pinggera, Germar-Michael, additional, Park, Hyun Jun, additional, Ghayda, Ramy Abou, additional, Minhas, Suks, additional, Busetto, Gian Maria, additional, Bakırcıoğlu, Mustafa Emre, additional, Kadioglu, Ates, additional, Chung, Eric, additional, Russo, Giorgio Ivan, additional, Calogero, Aldo E., additional, Ambar, Rafael F., additional, Jayasena, Channa N., additional, and Shah, Rupin, additional

Published
2023
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22. Impact of Varicocele Repair on Semen Parameters in Infertile Men: A Systematic Review and Meta-Analysis

Author

Agarwal, Ashok, primary, Cannarella, Rossella, additional, Saleh, Ramadan, additional, Boitrelle, Florence, additional, Gül, Murat, additional, Toprak, Tuncay, additional, Salvio, Gianmaria, additional, Arafa, Mohamed, additional, Russo, Giorgio I., additional, Harraz, Ahmed M., additional, Singh, Rajender, additional, Garrido, Nicolas, additional, Hamoda, Taha Abo-Almagd Abdel-Meguid, additional, Rambhatla, Amarnath, additional, Kavoussi, Parviz, additional, Kuroda, Shinnosuke, additional, Çalik, Gökhan, additional, Saini, Pallavi, additional, Ceyhan, Erman, additional, Dimitriadis, Fotios, additional, Henkel, Ralf, additional, Crafa, Andrea, additional, Palani, Ayad, additional, Duran, Mesut Berkan, additional, Maziotis, Evangelos, additional, Saïs, Émine, additional, Bendayan, Marion, additional, Darbandi, Mahsa, additional, Le, Tan V., additional, Gunes, Sezgin, additional, Tsioulou, Petroula, additional, Sengupta, Pallav, additional, Hazir, Berk, additional, Çeker, Gökhan, additional, Darbandi, Sara, additional, Durairajanayagam, Damayanthi, additional, Aghamajidi, Azin, additional, Alkhalidi, Noora, additional, Sogutdelen, Emrullah, additional, Leisegang, Kristian, additional, Alarbid, Abdullah, additional, Ho, Christopher C. K., additional, Malhotra, Vineet, additional, Finocchi, Federica, additional, Crisóstomo, Luís, additional, Kosgi, Raghavender, additional, ElBardisi, Haitham, additional, Zini, Armand, additional, Birowo, Ponco, additional, Colpi, Giovanni, additional, Park, Hyun Jun, additional, Serefoglu, Ege Can, additional, Nguyen, Quang, additional, Ko, Edmund, additional, de la Rosette, Jean, additional, Pinggera, Germar M., additional, Nguyen, Ho Vinh Phuoc, additional, Kandil, Hussein, additional, and Shah, Rupin, additional

Published
2023
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26. Controversy and Consensus on Indications for Sperm DNA Fragmentation Testing in Male Infertility: A Global Survey, Current Guidelines, and Expert Recommendations.

Author

Agarwal, Ashok, Farkouh, Ala’a, Saleh, Ramadan, Abdel-Meguid Hamoda, Taha Abo-Almagd, Harraz, Ahmed M., Kavoussi, Parviz, Arafa, Mohamed, Salvio, Gianmaria, Rambhatla, Amarnath, Toprak, Tuncay, Gül, Murat, Vinh Phuoc, Nguyen Ho, Boitrelle, Florence, Birowo, Ponco, Ghayda, Ramy Abou, Cannarella, Rossella, Kuroda, Shinnosuke, Durairajanayagam, Damayanthi, Zini, Armand, and Wyns, Christine

Subjects
DNA, MALE infertility, PROFESSIONALISM, INFERTILITY, ANDROGENS
Abstract

Purpose: Sperm DNA fragmentation (SDF) testing was recently added to the sixth edition of the World Health Organization laboratory manual for the examination and processing of human semen. Many conditions and risk factors have been associated with elevated SDF; therefore, it is important to identify the population of infertile men who might benefit from this test. The purpose of this study was to investigate global practices related to indications for SDF testing, compare the relevant professional society guideline recommendations, and provide expert recommendations. Materials and Methods: Clinicians managing male infertility were invited to take part in a global online survey on SDF clinical practices. This was conducted following the CHERRIES checklist criteria. The responses were compared to professional society guideline recommendations related to SDF and the appropriate available evidence. Expert recommendations on indications for SDF testing were then formulated, and the Delphi method was used to reach consensus. Results: The survey was completed by 436 experts from 55 countries. Almost 75% of respondents test for SDF in all or some men with unexplained or idiopathic infertility, 39% order it routinely in the work-up of recurrent pregnancy loss (RPL), and 62.2% investigate SDF in smokers. While 47% of reproductive urologists test SDF to support the decision for varicocele repair surgery when conventional semen parameters are normal, significantly fewer general urologists (23%; p=0.008) do the same. Nearly 70% would assess SDF before assisted reproductive technologies (ART), either always or for certain conditions. Recurrent ART failure is a common indication for SDF testing. Very few society recommendations were found regarding SDF testing. Conclusions: This article presents the largest global survey on the indications for SDF testing in infertile men, and demonstrates diverse practices. Furthermore, it highlights the paucity of professional society guideline recommendations. Expert recommendations are proposed to help guide clinicians. [ABSTRACT FROM AUTHOR]

Published
2023
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28. SINGLE COMPOUND ANTIOXIDANTS ARE SIMILARLY EFFECTIVE AS MULTI-COMPOUND ANTIOXIDANTS OVER A 3-MONTH PERIOD IN MEN WITH IDIOPATHIC INFERTILITY: A SYSTEMATIC REVIEW AND META-ANALYSIS

Author

Cannarella, Rossella, primary, Agarwal, Ashok, additional, Saleh, Ramadan, additional, Kandil, Hussein, additional, Salvio, Gianmaria, additional, Boitrelle, Florence, additional, Kuroda, Shinnosuke, additional, Farkouh, Ala'A., additional, Harraz, Ahmed, additional, Rambhatla, Amarnath, additional, Calogero, Aldo E., additional, and Shah, Rupin, additional

Published
2022
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29. Consensus and Diversity in the Management of Varicocele for Male Infertility: Results of a Global Practice Survey and Comparison with Guidelines and Recommendations

Author

Shah, Rupin, Agarwal, Ashok, Kavoussi, Parviz, Rambhatla, Amarnath, Saleh, Ramadan, Cannarella, Rossella, Harraz, Ahmed M., Boitrelle, Florence, Kuroda, Shinnosuke, Hamoda, Taha Abo-Almagd Abdel-Meguid, Zini, Armand, Ko, Edmund, Çalık, Gökhan, Toprak, Tuncay, Kandil, Hussein, Gül, Murat, Bakırcıoğlu, Mustafa Emre, Parekh, Neel, Russo, Giorgio Ivan, Tadros, Nicholas, Kadıoğlu, Ateş, Arafa, Mohamed, Chung, Eric, Rajmil, Osvaldo, Dimitriadis, Fotios, Malhotra, Vineet, Salvio, Gianmaria, Henkel, Ralf, Le, Tan V., Sogutdelen, Emrullah, Vij, Sarah, Alarbid, Abdullah, Güdeloğlu, Ahmet, Tsujimura, Akira, Calogero, Aldo E., El Meliegy, Amr, Crafa, Andrea, Kalkanlı, Arif, Baser, Aykut, Hazır, Berk, Giulioni, Carlo, Cho, Chak-Lam, Ho, Christopher C.K., Salzano, Ciro, Zylbersztejn, Daniel Suslik, Tien, Dung Mai Ba, Pescatori, Edoardo, Borges, Edson, Saïs-Hamza, Eminej, Huyghe, Eric, Ceyhan, Erman, Caroppo, Ettore, Castiglioni, Fabrizio, Bahar, Fahmi, Gökalp, Fatih, Lombardo, Francesco, Gadda, Franco, Duarsa, Gede Wirya Kusuma, Pinggera, Germar-Michael, Busetto, Gian Maria, Balercia, Giancarlo, Cito, Gianmartin, Blecher, Gideon, Franco, Giorgio, Liguori, Giovanni, Elbardisi, Haitham, Keskin, Hakan, Lin, Haocheng, Taniguchi, Hisanori, Park, Hyun Jun, Ziouziou, Imad, de la Rosette, Jean J. M. C. H., Hotaling, Jim, Ramsay, Jonathan, Molina, Juan Manuel Corral, Lo, Ka Lun, Böcü, Kadir, Khalafalla, Kareim, Bowa, Kasonde, Okada, Keisuke, Nagao, Koichi, Chiba, Koji, Hakim, Lukman, Makarounis, Konstantinos, Hehemann, Marah, Peña, Marcelo Rodriguez, Falcone, Marco, Bendayan, Marion, Martinez, Marlon, Timpano, Massimiliano, Altan, Mesut, Fode, Mikkel, Al-Marhoon, Mohamed S., Gilani, Mohammad Ali Sadighi, Soebadi, Mohammad Ayodhia, Gherabi, Nazim, Sofikitis, Nikolaos, Kahraman, Oğuzhan, Birowo, Ponco, Kothari, Priyank, Sindhwani, Puneet, Javed, Qaisar, Ambar, Rafael F., Kosgi, Raghavender, Ghayda, Ramy Abou, Adriansjah, Ricky, Condorelli, Rosita Angela, La Vignera, Sandro, Micic, Sava, Kim, Shannon Hee Kyung, Fukuhara, Shinichiro, Ahn, Sun Tae, Mostafa, Taymour, Ong, Teng Aik, Takeshima, Teppei, Amano, Toshiyasu, Barrett, Trenton, Arslan, Umut, Karthikeyan, Vilvapathy Senguttuvan, Atmoko, Widi, Yumura, Yasushi, Yuan, Yiming, Kato, Yuki, Jezek, Davor, Cheng, Bryan Kwun-Chung, Hatzichristodoulou, Georgios, Dy, Jun, Castañé, Eduard Ruiz, El-Sakka, Ahmed I., Nguyen, Quang, Sarıkaya, Selçuk, Boeri, Luca, Tan, Ronny, Moussa, Mohamad A., El-Assmy, Ahmed, Alali, Hamed, Alhathal, Naif, Osman, Yasser, Perovic, Dragoljub, Sajadi, Hesamoddin, Akhavizadegan, Hamed, Vučinić, Miroslav, Kattan, Said, Kattan, Mohamed S., Mogharabian, Nasser, Phuoc, Nguyen Ho Vinh, Ngoo, Kay Seong, Alkandari, Mohammad H., Alsuhaibani, Shaheed, Sokolakis, Ioannis, Babaei, Mehdi, King, Mak Siu, Diemer, Thorsten, Gava, Marcelo M., Henrique, Raphael, Spinola e Silva, Rodrigo, Paul, Gustavo Marquesine, Mierzwa, Tiago Cesar, Glina, Sidney, Siddiqi, Kashif, Wu, Han, Wurzacher, Jana, Farkouh, Ala'a, Son, Hwancheol, Minhas, Suks, Lee, Joe, Magsanoc, Nikko, Capogrosso, Paolo, Albano, German Jose, Lewis, Sheena E.M., Jayasena, Channa N., Alvarez, Juan G., Teo, Colin, Smith, Ryan P., Chua, Jo Ben M., Jensen, Christian Fuglesang S., Parekattil, Sijo, Finelli, Renata, Durairajanayagam, Damayanthi, Karna, Keshab Kumar, Ahmed, Abdelkareem, Evenson, Don, Umemoto, Yukihiro, Puigvert, Ana, Çeker, Gökhan, Colpi, Giovanni M., Rolitsky, Sarah, Bouzouita, Abderrazak, Shokeir, Ahmed, Aşçı, Ahmet, Bouker, Amin, Adamyan, Aram, Avoyan, Armen E., Palani, Ayad, Aghamajidi, Azin, Eze, Balantine, Noegroho, Bambang Sasongko, Purnomo, Basuki, Erkan, Bircan Kolbaşı, Zilaitiene, Birute, Kulaksız, Deniz, Kafetzis, Dimitrios, Lee, Dong Sup, Stember, Doron, Evgeni, Evangelini, Alhajeri, Faisal, Finocchi, Federica, Colombo, Fulvio, Tsangaris, George, Sallam, Hassan N., Acosta, Herik, Rosas, Israel Maldonado, Kirkman-Brown, Jackson, Shin, Jae Il, Sonksen, Jens, Dong, Jie, Marmar, Joel, Moreno-Sepulveda, Jose, Seo, Ju Tae, Aydos, Kaan, Kesari, Kavindra Kumar, Trost, Landon, Jenkins, Lawrence, Rocco, Lucia, Darbandi, Mahsa, Simopoulou, Mara, Alves, Marco, Sabbaghian, Marjan, Tavalaee, Marziyeh, Razi, Mazdak, Duran, Mesut Berkan, Nago, Mitsuru, Elkhouly, Mohamed, Khalili, Mohamed, Nasr-Esfahani, Mohammad Hossein, Kamath, Mohan S., Uğur, Muhammet Raşit, Park, Nam Cheol, Cruz, Natalio, Garrido, Nicolas, Sodeifi, Niloofar, Al Khalidi, Noora, Shoshany, Ohad, Satyagraha, Paksi, Drakopoulos, Panagiotos, Vogiatzi, Paraskevi, Dolati, Parisa, Das, Partha, Chiu, Peter Ka-Fung, Tsioulou, Petroula A., Patel, Premal, Singh, Rajender, Kaiyal, Raneen Sawaid, Santos, Ferreira, Dada, Rima, Brodjonegoro, Sakti, Banihani, Saleem Ali, Schon, Samantha, Darbandi, Sara, Güneş, Sezgin, Homa, Sheryl, Mutambirwa, Shingai, Roychoudhury, Shubhadeep, Diaz, Sofia Ines Leonardi, Gopalakrishnan, Sreelatha, Krawetz, Stephen, Jindal, Sunil, Avidor-Reiss, Tomer, Lin, Tsung Yen, Kumar, Vijay, Ibrahim, Wael, Kerkeni, Walid, Woo, Wongi, Morimoto, Yoshiharu, Cheng, Yu-Sheng, Shah, Rupin, Agarwal, Ashok, Kavoussi, Parviz, Rambhatla, Amarnath, Saleh, Ramadan, Cannarella, Rossella, Harraz, Ahmed M., Boitrelle, Florence, Kuroda, Shinnosuke, Hamoda, Taha Abo-Almagd Abdel-Meguid, Zini, Armand, Ko, Edmund, Calik, Gokhan, Toprak, Tuncay, Kandil, Hussein, Gül, Murat, Bakırcıoğlu, Mustafa Emre, Parekh, Neel, Russo, Giorgio Ivan, Tadros, Nichola, Kadioglu, Ate, Arafa, Mohamed, Chung, Eric, Rajmil, Osvaldo, Dimitriadis, Fotio, Malhotra, Vineet, Salvio, Gianmaria, Henkel, Ralf, Le, Tan V., Sogutdelen, Emrullah, Vij, Sarah, Alarbid, Abdullah, Gudeloglu, Ahmet, Tsujimura, Akira, Calogero, Aldo E., Meliegy, Amr El, Crafa, Andrea, Kalkanli, Arif, Baser, Aykut, Hazir, Berk, Giulioni, Carlo, Cho, Chak-Lam, Ho, Christopher C. K., Salzano, Ciro, Zylbersztejn, Daniel Suslik, Tien, Dung Mai Ba, Pescatori, Edoardo, Borges, Edson, Serefoglu, Ege Can, Sas-Hamza, Emine, Huyghe, Eric, Ceyhan, Erman, Caroppo, Ettore, Castiglioni, Fabrizio, Bahar, Fahmi, Gokalp, Fatih, Lombardo, Francesco, Gadda, Franco, Duarsa, Gede Wirya Kusuma, Pinggera, Germar-Michael, Busetto, Gian Maria, Balercia, Giancarlo, Cito, Gianmartin, Blecher, Gideon, Franco, Giorgio, Liguori, Giovanni, Elbardisi, Haitham, Keskin, Hakan, Lin, Haocheng, Taniguchi, Hisanori, Park, Hyun Jun, Ziouziou, Imad, Rosette, Jean de la, Hotaling, Jim, Ramsay, Jonathan, Molina, Juan Manuel Corral, Lo, Ka Lun, Bocu, Kadir, Khalafalla, Kareim, Bowa, Kasonde, Okada, Keisuke, Nagao, Koichi, Chiba, Koji, Hakim, Lukman, Makarounis, Konstantino, Hehemann, Marah, Peña, Marcelo Rodriguez, Falcone, Marco, Bendayan, Marion, Martinez, Marlon, Timpano, Massimiliano, Altan, Mesut, Fode, Mikkel, Al-Marhoon, Mohamed S., Gilani, Mohammad Ali Sadighi, Soebadi, Mohammad Ayodhia, Gherabi, Nazim, Sofikitis, Nikolao, Kahraman, Oğuzhan, Birowo, Ponco, Kothari, Priyank, Sindhwani, Puneet, Javed, Qaisar, Ambar, Rafael F., Kosgi, Raghavender, Ghayda, Ramy Abou, Adriansjah, Ricky, Condorelli, Rosita Angela, Vignera, Sandro La, Micic, Sava, Kim, Shannon Hee Kyung, Fukuhara, Shinichiro, Ahn, Sun Tae, Mostafa, Taymour, Ong, Teng Aik, Takeshima, Teppei, Amano, Toshiyasu, Barrett, Trenton, Arslan, Umut, Karthikeyan, Vilvapathy Senguttuvan, Atmoko, Widi, Yumura, Yasushi, Yuan, Yiming, Kato, Yuki, Jezek, Davor, Cheng, Bryan Kwun-Chung, Hatzichristodoulou, Georgio, Dy, Jun, Castañé, Eduard Ruiz, El-Sakka, Ahmed I., Nguyen, Quang, Sarikaya, Selcuk, Boeri, Luca, Tan, Ronny, Moussa, Mohamad A., El-Assmy, Ahmed, Alali, Hamed, Alhathal, Naif, Osman, Yasser, Perovic, Dragoljub, Sajadi, Hesamoddin, Akhavizadegan, Hamed, Vučinić, Miroslav, Kattan, Said, Kattan, Mohamed S., Mogharabian, Nasser, Phuoc, Nguyen Ho Vinh, Ngoo, Kay Seong, Alkandari, Mohammad H., Alsuhaibani, Shaheed, Sokolakis, Ioanni, Babaei, Mehdi, King, Mak Siu, Diemer, Thorsten, Gava, Marcelo M., Henrique, Raphael, Silva, Rodrigo Spinola e, Paul, Gustavo Marquesine, Mierzwa, Tiago Cesar, Glina, Sidney, Siddiqi, Kashif, Wu, Han, Wurzacher, Jana, Farkouh, Ala’A, Son, Hwancheol, Minhas, Suk, Lee, Joe, Magsanoc, Nikko, Capogrosso, Paolo, Albano, German Jose, Lewis, Sheena E. M., Jayasena, Channa N., Alvarez, Juan G., Teo, Colin, Smith, Ryan P., Chua, Jo Ben M., Jensen, Christian Fuglesang S., Parekattil, Sijo, Finelli, Renata, Durairajanayagam, Damayanthi, Karna, Keshab Kumar, Ahmed, Abdelkareem, Evenson, Don, Umemoto, Yukihiro, Puigvert, Ana, Çeker, Gökhan, Forum, Giovanni M Colpi, Shah, R., Agarwal, A., Kavoussi, P., Rambhatla, A., Saleh, R., Cannarella, R., Harraz, A. M., Boitrelle, F., Kuroda, S., Hamoda, T. A. -A. A. -M., Zini, A., Ko, E., Calik, G., Toprak, T., Kandil, H., Gul, M., Bakircioglu, M. E., Parekh, N., Russo, G. I., Tadros, N., Kadioglu, A., Arafa, M., Chung, E., Rajmil, O., Dimitriadis, F., Malhotra, V., Salvio, G., Henkel, R., Le, T. V., Sogutdelen, E., Vij, S., Alarbid, A., Gudeloglu, A., Tsujimura, A., Calogero, A. E., El Meliegy, A., Crafa, A., Kalkanli, A., Baser, A., Hazir, B., Giulioni, C., Cho, C. -L., Ho, C. C. K., Salzano, C., Zylbersztejn, D. S., Tien, D. M. B., Pescatori, E., Borges, E., Serefoglu, E. C., Sais-Hamza, E., Huyghe, E., Ceyhan, E., Caroppo, E., Castiglioni, F., Bahar, F., Gokalp, F., Lombardo, F., Gadda, F., Duarsa, G. W. K., Pinggera, G. -M., Busetto, G. M., Balercia, G., Cito, G., Blecher, G., Franco, G., Liguori, G., Elbardisi, H., Keskin, H., Lin, H., Taniguchi, H., Park, H. J., Ziouziou, I., de la Rosette, J., Hotaling, J., Ramsay, J., Molina, J. M. C., Lo, K. L., Bocu, K., Khalafalla, K., Bowa, K., Okada, K., Nagao, K., Chiba, K., Hakim, L., Makarounis, K., Hehemann, M., Pena, M. R., Falcone, M., Bendayan, M., Martinez, M., Timpano, M., Altan, M., Fode, M., Al-Marhoon, M. S., Gilani, M. A. S., Soebadi, M. A., Gherabi, N., Sofikitis, N., Kahraman, O., Birowo, P., Kothari, P., Sindhwani, P., Javed, Q., Ambar, R. F., Kosgi, R., Ghayda, R. A., Adriansjah, R., Condorelli, R. A., La Vignera, S., Micic, S., Kim, S. H. K., Fukuhara, S., Ahn, S. T., Mostafa, T., Ong, T. A., Takeshima, T., Amano, T., Barrett, T., Arslan, U., Karthikeyan, V. S., Atmoko, W., Yumura, Y., Yuan, Y., Kato, Y., Jezek, D., Cheng, B. K. -C., Hatzichristodoulou, G., Dy, J., Castane, E. R., El-Sakka, A. I., Nguyen, Q., Sarikaya, S., Boeri, L., Tan, R., Moussa, M. A., El-Assmy, A., Alali, H., Alhathal, N., Osman, Y., Perovic, D., Sajadi, H., Akhavizadegan, H., Vucinic, M., Kattan, S., Kattan, M. S., Mogharabian, N., Phuoc, N. H. V., Ngoo, K. S., Alkandari, M. H., Alsuhaibani, S., Sokolakis, I., Babaei, M., King, M. S., Diemer, T., Gava, M. M., Henrique, R., Spinola e Silva, R., Paul, G. M., Mierzwa, T. C., Glina, S., Siddiqi, K., Wu, H., Wurzacher, J., Farkouh, A., Son, H., Minhas, S., Lee, J., Magsanoc, N., Capogrosso, P., Albano, G. J., Lewis, S. E. M., Jayasena, C. N., Alvarez, J. G., Teo, C., Smith, R. P., Chua, J. B. M., Jensen, C. F. S., Parekattil, S., Finelli, R., Durairajanayagam, D., Karna, K. K., Ahmed, A., Evenson, D., Umemoto, Y., Puigvert, A., Ceker, G., Colpi, G. M., Rolitsky, S., Bouzouita, A., Shokeir, A., Asci, A., Bouker, A., Adamyan, A., Avoyan, A. E., Palani, A., Aghamajidi, A., Eze, B., Noegroho, B. S., Purnomo, B., Erkan, B. K., Zilaitiene, B., Kulaksiz, D., Kafetzis, D., Lee, D. S., Stember, D., Evgeni, E., Alhajeri, F., Finocchi, F., Colombo, F., Tsangaris, G., Sallam, H. N., Acosta, H., Rosas, I. M., Kirkman-Brown, J., Shin, J. I., Sonksen, J., Dong, J., Marmar, J., Moreno-Sepulveda, J., Seo, J. T., Aydos, K., Kesari, K. K., Trost, L., Jenkins, L., Rocco, L., Darbandi, M., Simopoulou, M., Alves, M., Sabbaghian, M., Tavalaee, M., Razi, M., Duran, M. B., Nago, M., Elkhouly, M., Khalili, M., Nasr-Esfahani, M. H., Kamath, M. S., Ugur, M. R., Park, N. C., Cruz, N., Garrido, N., Sodeifi, N., Al Khalidi, N., Shoshany, O., Satyagraha, P., Drakopoulos, P., Vogiatzi, P., Dolati, P., Das, P., Chiu, P. K. -F., Tsioulou, P. A., Patel, P., Singh, R., Kaiyal, R. S., Santos, F., Dada, R., Brodjonegoro, S., Banihani, S. A., Schon, S., Darbandi, S., Gunes, S., Homa, S., Mutambirwa, S., Roychoudhury, S., Diaz, S. I. L., Gopalakrishnan, S., Krawetz, S., Jindal, S., Avidor-Reiss, T., Lin, T. Y., Kumar, V., Ibrahim, W., Kerkeni, W., Woo, W., Morimoto, Y., Cheng, Y. -S., and Tıp Fakültesi

Subjects
Aging, Consensus, Urology, INGUINAL VARICOCELECTOMY, Disease management, Male infertility, Survey, Varicocele, Consensu, Global Andrology Forum, Endocrinology & Metabolism, NONOBSTRUCTIVE AZOOSPERMIA, ASSISTED REPRODUCTIVE TECHNOLOGY, Male Infertility, Pharmacology (medical), Andrology, IMPAIRED SEMEN QUALITY, EUROPEAN ASSOCIATION, Science & Technology, UROLOGY GUIDELINES, Health Policy, Public Health, Environmental and Occupational Health, Disease Management, Urology & Nephrology, SUBCLINICAL VARICOCELE, Psychiatry and Mental health, Health Care Sciences & Services, MICROSURGICAL SUBINGUINAL VARICOCELECTOMY, Reproductive Medicine, SPERM MORPHOLOGY, UNTREATED VARICOCELE, Life Sciences & Biomedicine
Abstract

Purpose: Varicocele is a common problem among infertile men. Varicocele repair (VR) is frequently performed to improve semen parameters and the chances of pregnancy. However, there is a lack of consensus about the diagnosis, indications for VR and its outcomes. The aim of this study was to explore global practice patterns on the management of varicocele in the context of male infertility. Materials and Methods: Sixty practicing urologists/andrologists from 23 countries contributed 382 multiple-choice-questions pertaining to varicocele management. These were condensed into an online questionnaire that was forwarded to clinicians involved in male infertility management through direct invitation. The results were analyzed for disagreement and agreement in practice patterns and, compared with the latest guidelines of international professional societies (American Urological As- sociation [AUA], American Society for Reproductive Medicine [ASRM], and European Association of Urology [EAU]), and with evidence emerging from recent systematic reviews and meta-analyses. Additionally, an expert opinion on each topic was provided based on the consensus of 16 experts in the field. Results: The questionnaire was answered by 574 clinicians from 59 countries. The majority of respondents were urologists/ uro-andrologists. A wide diversity of opinion was seen in every aspect of varicocele diagnosis, indications for repair, choice of technique, management of sub-clinical varicocele and the role of VR in azoospermia. A significant proportion of the re- sponses were at odds with the recommendations of AUA, ASRM, and EAU. A large number of clinical situations were identi- fied where no guidelines are available. Conclusions: This study is the largest global survey performed to date on the clinical management of varicocele for male in- fertility. It demonstrates: 1) a wide disagreement in the approach to varicocele management, 2) large gaps in the clinical prac- tice guidelines from professional societies, and 3) the need for further studies on several aspects of varicocele management in infertile men.

Published
2022

30. Optimizing embryological aspects of oocyte retrieval, oocyte denudation, and embryo loading for transfer

Author

MALDONADO ROSAS, Israel, primary, ANAGNOSTOPOULOU, Christina, additional, SINGH, Neha, additional, GUGNANI, Nivita, additional, SINGH, Keerti, additional, DESAI, Dimple, additional, DARBANDI, Mahsa, additional, MANOHARAN, Madhumita, additional, DARBANDI, Sara, additional, CHOCKALINGAM, Annapoorani, additional, LEONARDI DIAZ, Sofia I., additional, GUPTA, Sajal, additional, KURODA, Shinnosuke, additional, FINELLI, Renata, additional, SALLAM, Hassan N., additional, WIRKA, Kelly A., additional, BOITRELLE, Florence, additional, and AGARWAL, Ashok, additional

Published
2022
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34. Consensus and Diversity in the Management of Varicocele for Male Infertility: Results of a Global Practice Survey and Comparison with Guidelines and Recommendations.

Author

Shah, Rupin, Agarwal, Ashok, Kavoussi, Parviz, Rambhatla, Amarnath, Saleh, Ramadan, Cannarella, Rossella, Harraz, Ahmed M., Boitrelle, Florence, Kuroda, Shinnosuke, Abdel-Meguid Hamoda, Taha Abo-Almagd, Zini, Armand, Ko, Edmund, Calik, Gokhan, Toprak, Tuncay, Kandil, Hussein, Gül, Murat, Bakırcıoğlu, Mustafa Emre, Parekh, Neel, Russo, Giorgio Ivan, and Tadros, Nicholas

Subjects
VARICOCELE, MALE infertility treatment, CLINICAL trials, UROLOGISTS
Abstract

Purpose: Varicocele is a common problem among infertile men. Varicocele repair (VR) is frequently performed to improve semen parameters and the chances of pregnancy. However, there is a lack of consensus about the diagnosis, indications for VR and its outcomes. The aim of this study was to explore global practice patterns on the management of varicocele in the context of male infertility. Materials and Methods: Sixty practicing urologists/andrologists from 23 countries contributed 382 multiple-choice-questions pertaining to varicocele management. These were condensed into an online questionnaire that was forwarded to clinicians involved in male infertility management through direct invitation. The results were analyzed for disagreement and agreement in practice patterns and, compared with the latest guidelines of international professional societies (American Urological Association [AUA], American Society for Reproductive Medicine [ASRM], and European Association of Urology [EAU]), and with evidence emerging from recent systematic reviews and meta-analyses. Additionally, an expert opinion on each topic was provided based on the consensus of 16 experts in the field. Results: The questionnaire was answered by 574 clinicians from 59 countries. The majority of respondents were urologists/ uro-andrologists. A wide diversity of opinion was seen in every aspect of varicocele diagnosis, indications for repair, choice of technique, management of sub-clinical varicocele and the role of VR in azoospermia. A significant proportion of the responses were at odds with the recommendations of AUA, ASRM, and EAU. A large number of clinical situations were identified where no guidelines are available. Conclusions: This study is the largest global survey performed to date on the clinical management of varicocele for male infertility. It demonstrates: 1) a wide disagreement in the approach to varicocele management, 2) large gaps in the clinical practice guidelines from professional societies, and 3) the need for further studies on several aspects of varicocele management in infertile men. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Effects of antioxidant co‐supplementation therapy on spermatogenesis dysfunction in relation to the basal oxidation–reduction potential levels in spermatozoa: A pilot study

Author

Yamasaki, Kazumitsu, primary, Uchida, Masahiro, additional, Watanabe, Noriko, additional, Ihana, Tatsuji, additional, Ishiguro, Yukari, additional, Kuroda, Shinnosuke, additional, Takeshima, Teppei, additional, Yumura, Yasushi, additional, Mieno, Makiko, additional, Yoshida, Kaoru, additional, Iwamoto, Teruaki, additional, and Nishiyama, Hiroyuki, additional

Published
2022
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36. Guidelines for Reproductive Medicine in Japan

Author

Yamada, Mitsutoshi, primary, Ishikawa, Tomonori, additional, Iwasa, Takeshi, additional, Oishi, Hajime, additional, Osuka, Satoko, additional, Oka, Kenji, additional, Ono, Shuichi, additional, Ono, Masanori, additional, Orisaka, Makoto, additional, Kanasaki, Haruhiko, additional, Kawano, Yasushi, additional, Kawamura, Kazuhiro, additional, Kishi, Hiroshi, additional, Kimura, Fuminori, additional, Kuroda, Shinnosuke, additional, Kuwahara, Akira, additional, Kobayashi, Hideyuki, additional, Komiya, Akira, additional, Saito, Hidekazu, additional, Sato, Kenji, additional, Sato, Suguru, additional, Shiraishi, Koji, additional, Shirasawa, Hiromitsu, additional, Suzuki, Tatsuya, additional, Takai, Yasushi, additional, Takae, Seido, additional, Takahashi, Toshifumi, additional, Takiuchi, Tsuyoshi, additional, Tachibana, Masahito, additional, Tamura, Isao, additional, Tamura, Hiroshi, additional, Jwa, Seung Chik, additional, Baba, Tsuyoshi, additional, Harada, Miyuki, additional, Hirata, Tetsuya, additional, Fukui, Atsushi, additional, Fukuda, Yusuke, additional, Fukuhara, Shinichiro, additional, Maruyama, Tetsuo, additional, Yumura, Yasushi, additional, Yoshino, Osamu, additional, Hirota, Yasushi, additional, Tsujimura, Akira, additional, Kuji, Naoaki, additional, and Osuga, Yutaka, additional

Published
2022
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38. Sperm Vitality and Necrozoospermia: Diagnosis, Management, and Results of a Global Survey of Clinical Practice

Author

Agarwal, Ashok, primary, Sharma, Rakesh K., additional, Gupta, Sajal, additional, Boitrelle, Florence, additional, Finelli, Renata, additional, Parekh, Neel, additional, Durairajanayagam, Damayanthi, additional, Saleh, Ramadan, additional, Arafa, Mohamed, additional, Cho, Chak Lam, additional, Farkouh, Ala'a, additional, Rambhatla, Amarnath, additional, Henkel, Ralf, additional, Vogiatzi, Paraskevi, additional, Tadros, Nicholas, additional, Kavoussi, Parviz, additional, Ko, Edmund, additional, Leisegang, Kristian, additional, Kandil, Hussein, additional, Palani, Ayad, additional, Salvio, Gianmaria, additional, Mostafa, Taymour, additional, Rajmil, Osvaldo, additional, Banihani, Saleem Ali, additional, Schon, Samantha, additional, Le, Tan V., additional, Birowo, Ponco, additional, Çeker, Gökhan, additional, Alvarez, Juan, additional, Molina, Juan Manuel Corral, additional, Ho, Christopher C.K., additional, Calogero, Aldo E., additional, Khalafalla, Kareim, additional, Duran, Mesut Berkan, additional, Kuroda, Shinnosuke, additional, Colpi, Giovanni M., additional, Zini, Armand, additional, Anagnostopoulou, Christina, additional, Pescatori, Edoardo, additional, Chung, Eric, additional, Caroppo, Ettore, additional, Dimitriadis, Fotios, additional, Pinggera, Germar-Michael, additional, Busetto, Gian Maria, additional, Balercia, Giancarlo, additional, Elbardisi, Haitham, additional, Taniguchi, Hisanori, additional, Park, Hyun Jun, additional, Maldonado Rosas, Israel, additional, de la Rosette, Jean, additional, Ramsay, Jonathan, additional, Bowa, Kasonde, additional, Simopoulou, Mara, additional, Rodriguez, Marcelo Gabriel, additional, Sabbaghian, Marjan, additional, Martinez, Marlon, additional, Gilani, Mohamed Ali Sadighi, additional, Al-Marhoon, Mohamed S., additional, Kosgi, Raghavender, additional, Cannarella, Rossella, additional, Micic, Sava, additional, Fukuhara, Shinichiro, additional, Parekattil, Sijo, additional, Jindal, Sunil, additional, Abdel-Meguid, Taha Abo-Almagd, additional, Morimoto, Yoshiharu, additional, and Shah, Rupin, additional

Published
2022
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40. Role of Cytocentrifugation Combined with Nuclear Fast Picroindigocarmine Staining in Detecting Cryptozoospermia in Men Diagnosed with Azoospermia

Author

Sharma, Rakesh Kumar, primary, Gupta, Sajal, additional, Agarwal, Ashok, additional, Finelli, Renata, additional, Kuroda, Shinnosuke, additional, Saleh, Ramadan, additional, Boitrelle, Florence, additional, Kavoussi, Parviz, additional, Gül, Murat, additional, Tadros, Nicholas, additional, Ko, Edmund, additional, Farkouh, Ala’a, additional, Henkel, Ralf, additional, Arafa, Mohamed, additional, Rambhatla, Amarnath, additional, and Shah, Rupin, additional

Published
2022
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41. Antisperm Antibody Testing: A Comprehensive Review of Its Role in the Management of Immunological Male Infertility and Results of a Global Survey of Clinical Practices

Author

Gupta, Sajal, primary, Sharma, Rakesh, additional, Agarwal, Ashok, additional, Boitrelle, Florence, additional, Finelli, Renata, additional, Farkouh, Ala'a, additional, Saleh, Ramadan, additional, Abdel-Meguid, Taha Abo-Almagd, additional, Gül, Murat, additional, Zilaitiene, Birute, additional, Ko, Edmund, additional, Rambhatla, Amarnath, additional, Zini, Armand, additional, Leisegang, Kristian, additional, Kuroda, Shinnosuke, additional, Henkel, Ralf, additional, Cannarella, Rossella, additional, Palani, Ayad, additional, Cho, Chak-Lam, additional, Ho, Christopher C.K., additional, Zylbersztejn, Daniel Suslik, additional, Pescatori, Edoardo, additional, Chung, Eric, additional, Dimitriadis, Fotios, additional, Pinggera, Germar-Michael, additional, Busetto, Gian Maria, additional, Balercia, Giancarlo, additional, Salvio, Gianmaria, additional, Colpi, Giovanni M., additional, Çeker, Gökhan, additional, Taniguchi, Hisanori, additional, Kandil, Hussein, additional, Park, Hyun Jun, additional, Maldonado Rosas, Israel, additional, de la Rosette, Jean, additional, Cardoso, Joao Paulo Greco, additional, Ramsay, Jonathan, additional, Alvarez, Juan, additional, Molina, Juan Manuel Corral, additional, Khalafalla, Kareim, additional, Bowa, Kasonde, additional, Tremellen, Kelton, additional, Evgeni, Evangelini, additional, Rocco, Lucia, additional, Rodriguez Peña, Marcelo Gabriel, additional, Sabbaghian, Marjan, additional, Martinez, Marlon, additional, Arafa, Mohamed, additional, Al-Marhoon, Mohamed S., additional, Tadros, Nicholas, additional, Garrido, Nicolas, additional, Rajmil, Osvaldo, additional, Sengupta, Pallav, additional, Vogiatzi, Paraskevi, additional, Kavoussi, Parviz, additional, Birowo, Ponco, additional, Kosgi, Raghavender, additional, Bani-Hani, Saleem, additional, Micic, Sava, additional, Parekattil, Sijo, additional, Jindal, Sunil, additional, Le, Tan V., additional, Mostafa, Taymour, additional, Toprak, Tuncay, additional, Morimoto, Yoshiharu, additional, Malhotra, Vineet, additional, Aghamajidi, Azin, additional, Durairajanayagam, Damayanthi, additional, and Shah, Rupin, additional

Published
2022
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42. Post-Vasectomy Semen Analysis: Optimizing Laboratory Procedures and Test Interpretation through a Clinical Audit and Global Survey of Practices

Author

Agarwal, Ashok, primary, Gupta, Sajal, additional, Sharma, Rakesh K., additional, Finelli, Renata, additional, Kuroda, Shinnosuke, additional, Vij, Sarah C., additional, Boitrelle, Florence, additional, Kavoussi, Parviz, additional, Rambhatla, Amarnath, additional, Saleh, Ramadan, additional, Chung, Eric, additional, Mostafa, Taymour, additional, Zini, Armand, additional, Ko, Edmund, additional, Parekh, Neel, additional, Martinez, Marlon, additional, Arafa, Mohamed, additional, Tadros, Nicholas, additional, de la Rosette, Jean, additional, Le, Tan V., additional, Rajmil, Osvaldo, additional, Kandil, Hussein, additional, Blecher, Gideon, additional, Liguori, Giovanni, additional, Caroppo, Ettore, additional, Ho, Christopher C.K., additional, Altman, Andrew, additional, Bajic, Petar, additional, Goldfarb, David, additional, Gill, Bradley, additional, Zylbersztejn, Daniel Suslik, additional, Molina, Juan Manuel Corral, additional, Gava, Marcello M., additional, Cardoso, Joao Paulo Greco, additional, Kosgi, Raghavender, additional, Çeker, Gökhan, additional, Zilaitiene, Birute, additional, Pescatori, Edoardo, additional, Borges, Edson, additional, Duarsa, Gede Wirya Kusuma, additional, Pinggera, Germar-Michael, additional, Busetto, Gian Maria, additional, Balercia, Giancarlo, additional, Franco, Giorgio, additional, Çalik, Gökhan, additional, Sallam, Hassan N., additional, Park, Hyun Jun, additional, Ramsay, Jonathan, additional, Alvarez, Juan, additional, Khalafalla, Kareim, additional, Bowa, Kasonde, additional, Hakim, Lukman, additional, Simopoulou, Mara, additional, Rodriguez, Marcelo Gabriel, additional, Sabbaghian, Marjan, additional, Elbardisi, Haitham, additional, Timpano, Massimiliano, additional, Altan, Mesut, additional, Elkhouly, Mohamed, additional, Al-Marhoon, Mohamed S., additional, Sadighi Gilani, Mohammad Ali, additional, Soebadi, Mohammad Ayodhia, additional, Nasr-Esfahani, Mohammad Hossein, additional, Garrido, Nicolas, additional, Vogiatzi, Paraskevi, additional, Birowo, Ponco, additional, Patel, Premal, additional, Javed, Qaisar, additional, Ambar, Rafael F., additional, Adriansjah, Ricky, additional, AlSaid, Sami, additional, Micic, Sava, additional, Lewis, Sheena E., additional, Mutambirwa, Shingai, additional, Fukuhara, Shinichiro, additional, Parekattil, Sijo, additional, Ahn, Sun Tae, additional, Jindal, Sunil, additional, Takeshima, Teppei, additional, Puigvert, Ana, additional, Amano, Toshiyasu, additional, Barrett, Trenton, additional, Toprak, Tuncay, additional, Malhotra, Vineet, additional, Atmoko, Widi, additional, Yumura, Yasushi, additional, Morimoto, Yoshiharu, additional, Lima, Thiago Fernandes Negris, additional, Kunz, Yannic, additional, Kato, Yuki, additional, Umemoto, Yukihiro, additional, Colpi, Giovanni M., additional, Durairajanayagam, Damayanthi, additional, and Shah, Rupin, additional

Published
2022
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43. Sperm vitality and necrozoospermia: Diagnosis, management, and results of a global survey of clinical practice

Author

Agarwal, Ashok, Sharma, Rakesh K., Gupta, Sajal, Boitrelle, Florence, Finelli, Renata, Parekh, Neel, Durairajanayagam, Damayanthi, Saleh, Ramadan, Arafa, Mohamed, Cho, Chak Lam, Farkouh, Ala’a, Rambhatla, Amarnath, Henkel, Ralf, Vogiatzi, Paraskevi, Tadros, Nicholas, Kavoussi, Parviz, Ko, Edmund, Leisegang, Kristian, Kandil, Hussein, Palani, Ayad, Salvio, Gianmaria, Mostafa, Taymour, Rajmil, Osvaldo, Banihani, Saleem Ali, Schon, Samantha, Le, Tan V., Birowo, Ponco, Çeker, Gökhan, Alvarez, Juan, Molina, Juan Manuel Corral, Ho, Christopher C.K., Calogero, Aldo E., Khalafalla, Kareim, Duran, Mesut Berkan, Kuroda, Shinnosuke, Colpi, Giovanni M., Zini, Armand, Anagnostopoulou, Christina, Pescatori, Edoardo, Chung, Eric, Caroppo, Ettore, Dimitriadis, Fotios, Pinggera, Germar-Michael, Busetto, Gian Maria, Balercia, Giancarlo, Elbardisi, Haitham, Taniguchi, Hisanori, Park, Hyun Jun, Rosas, Israel Maldonado, de la Rosette, Jean J. M. C. H., Ramsay, Jonathan, Bowa, Kasonde, Simopoulou, Mara, Rodriguez, Marcelo Gabriel, Sabbaghian, Marjan, Martinez, Marlon, Gilani, Mohamed Ali Sadighi, Al-Marhoon, Mohamed S., Kosgi, Raghavender, Cannarella, Rossella, Micic, Sava, Fukuhara, Shinichiro, Parekattil, Sijo, Jindal, Sunil, Abdel-Meguid, Taha Abo-Almagd, Morimoto, Yoshiharu, and Shah, Rupin

Subjects
Nigrosin, endocrine system, urogenital system, Asthenozoospermia, Infertility, Eosine Yellowish-(YS), Vitality, Spermatozoa
Abstract

Sperm vitality testing is a basic semen examination that has been described in the World Health Organization (WHO) Laboratory Manual for the Examination and Processing of Human Semen from its primary edition, 40 years ago. Several methods can be used to test sperm vitality, such as the eosin-nigrosin (E-N) stain or the hypoosmotic swelling (HOS) test. In the 6th (2021) edition of the WHO Laboratory Manual, sperm vitality assessment is mainly recommended if the total motility is less than 40%. Hence, a motile spermatozoon is considered alive, however, in certain conditions an immotile spermatozoon can also be alive. Therefore, the differentiation between asthenozoospermia (pathological decrease in sperm motility) and necrozoospermia (pathological decrease in sperm vitality) is important in directing further investigation and management of infertile patients. The causes leading to necrozoospermia are diverse and can either be local or general, testicular or extra -testicular. The andrological management of necrozoospermia depends on its etiology. However, there is no standardized treatment available presently and practice varies among clinicians. In this study, we report the results of a global survey to understand current practices regarding the physician order of sperm vitality tests as well as the management practices for necrozoospermia. Laboratory and clinical scenarios are presented to guide the reader in the management of necrozoospermia with the overall objective of establishing a benchmark ranging from the diagnosis of necrozoospermia by sperm vitality testing to its clinical management. American Center for Reproductive Medicine

Published
2021

47. HIGH MITOCHONDRIAL DNA REPLICATION IN EMBRYOS DERIVED FROM MYOTONIC DYSTROPHY 1 FEMALE

Author

Ijuin, Akifumi, primary, Hayama, Tomonari, additional, Yamamoto, Mizuki, additional, Ueno, Hiroe, additional, Hamada, Haru, additional, Miyakoshi, Ai, additional, Nishi, Mayuko, additional, Saito, Marina, additional, Tochihara, Shiori, additional, Takeshima, Teppei, additional, Kuroda, Shinnosuke, additional, Sakakibara, Hideya, additional, Yumura, Yasushi, additional, Miyagi, Etsuko, additional, and Murase, Mariko, additional

Published
2021
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49. ADD-ON EFFECT OF ORAL ANTIOXIDANT THERAPY TO SURGICAL VARICOCELECTOMY ON THE OUTCOME OF ASSISTED REPRODUCTIVE TECHNOLOGY: A SINGLE-CENTER RETROSPECTIVE COHORT STUDY

Author

Takeshima, Teppei, primary, Kuroda, Shinnosuke, additional, Komeya, Mitsuru, additional, Saito, Marina, additional, Nishi, Mayuko, additional, Ueno, Hiroe, additional, Yamamoto, Mizuki, additional, Ijuin, Akifumi, additional, Hamada, Haru, additional, Miyakoshi, Ai, additional, Hayama, Tomonari, additional, Murase, Mariko, additional, and Yumura, Yasushi, additional

Published
2021
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50. 不妊を契機に発見された多精巣症の1例

Author

Iwamoto, Genta, Takeshima, Teppei, Kuroda, Shinnosuke, Yumura, Yasushi, and Uemura, Hiroji

Subjects
endocrine system, urogenital system, Infertility, Testicular sperm extraction, Testis, Polyorchidism, 494.9, urologic and male genital diseases, Cryptozoospermia
Abstract

A 30-year-old man present with infertility for 2 years. Magnetic resonance imaging (MRI) revealed two right testes in the scrotum and inguinal region, respectively. Semen analysis revealed cryptozoospermia. Polyorchidism was considered to have caused spermatogenic dysfunction and male infertility. We performed right high orchiectomy and simultaneous testicular sperm extraction on the same testis. To our knowledge, this is the first case of testicular sperm extraction performed for patients with polyorchidism.

Published
2019

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