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When classroom facilities are out of date, students complain (Habaci et al., in Procedia Soc Behav Sci 64:58-64 2012, https://doi.org/10.1016/j.sbspro.2012.11.008). But, before students arrive on campus, what do they know about their classrooms? Media has changed how people acquire information; websites are second only to college tours in influencing prospective students (Langmead in How college websites influence students' web experience. eCampusNews. Today's Innovation in Education (2013). https://www.ecampusnews.com/2013/03/21/how-college-websites-influence-students-web-experience/?all); furthermore, photographs impact website design (Kolowich in 14 of the best college websites (And why they're so awesome) (2019), Hubspot. https://blog.hubspot.com/marketing/best-college-websites). Can photographed classrooms influence judgments of the institution itself? In this 2 × 2 between-subjects experiment, participants read a scenario about a college too far away to visit and viewed a website picture of a seminar room (unrenovated or renovated) before responding to measures of classroom satisfaction and college academic life more broadly (e.g., student retention). Institutional rank (mentioned or not), was the 2nd variable. Participants were 300 AmazonMTurk workers, 237 of whom passed manipulation checks and were retained in analyses. The classroom furnishings comprised a scale (10 items, Cronbach's alpha = 0.879), as did questions dealing with perceptions of the institution (9 items, Cronbach's alpha = 0.897). Analyses revealed a significant main effect for renovation status, for both the furnishings scale (p < 0.001) and perceptions of the institution (p < 0.001), but not for rank (p = 0.052), with an institution being ranked in the top 50 being viewed more positively. For renovation status, the newer classroom was viewed more positively for both scales. Classroom status also significantly influenced estimates of first-year student retention (renovation status, p < 0.001; rank, p = 0.027), with higher estimates of retention for the renovated classroom and when rank was mentioned.

This paper reads the sale of citizenship via citizenship‐by‐investment (CBI) programmes through an offshore lens. Scholarship on offshore industries has long positioned citizenship sales as part of offshore capitalism—without exploring the phenomenon in any depth. Research on CBI, in turn, has with some notable exceptions neglected the phenomenon's offshore nature. This paper argues that CBI is an outgrowth and increasingly integral part of offshore capitalism, offering a new form of what Susan Roberts calls “regulatory arbitrage”, aiding elite wealth accumulation and power. The paper establishes this relationship by examining the countries and firms selling citizenship, their marketing strategies and customers and, crucially, the nature of the product which rests on the three “offshore pillars”, as described by Ronen Palan—virtual residency, easy incorporation, and secrecy. Conceptualising CBI as an offshore provision can transform how the phenomenon is understood and opens new avenues of thinking about its socio‐structural role and impact in an unequal world. [ABSTRACT FROM AUTHOR]

Although antibodies remain the most widely used tool for biomedical research, antibody technology is not flawless. Innovative alternatives, such as Nanobody® molecules, were developed to address the shortcomings of conventional antibodies. Nanobody® molecules are antigen-binding variable-domain fragments derived from the heavy-chain-only antibodies of camelids (VHH) and combine the advantageous properties of small molecules and monoclonal antibodies. Nanobody® molecules present a small size (~15 kDa, 4 nm long and 2.5 nm wide), high solubility, stability, specificity, and affinity, ease of cloning, and thermal and chemical resistance. Recombinant production in microorganisms is cost-effective, and VHH are also building blocks for multidomain constructs. These unique features led to numerous applications in fundamental research, diagnostics, and therapy. Nanobody® molecules are employed as biomarker probes and, when fused to radioisotopes or fluorophores, represent ideal non-invasive in vivo imaging agents. They can be used as neutralizing agents, receptor-ligand antagonists, or in targeted vehicle-based drug therapy. As early as 2018, the first Nanobody®, Cablivi (caplacizumab), a single-domain antibody (sdAb) drug developed by French pharmaceutical giant Sanofi for the treatment of adult patients with acquired thrombocytopenic purpura (aTTP), was launched. Nanobody® compounds are ideal tools for further development in clinics for diagnostic and therapeutic purposes. [ABSTRACT FROM AUTHOR]

Background: Neonatal patients who no longer require level IV neonatal intensive care unit care are transferred to less acute levels of care. Standardized assessment tools have been shown to be beneficial in the transfer of patient care. However, no standardized tools were available to assist neonatal providers in the assessment and communication of the infants needs at transfer.Purpose: The purpose was to develop a Transfer Assessment and Communication Tool (TACT) that guides provider decision making in the transfer of infants from a level IV neonatal intensive care unit to a less acute level of care within a regionalized healthcare system.Methods: Phase 1 included developing the first draft of the TACT using retrospective data, known variables from published literature, and study team expertise. In phase 2, the final draft of the TACT was created through feedback from expert neonatal providers in the regionalized care system using e-Delphi methodology.Results: The first draft of the TACT, developed in phase 1, included 36 characteristics. In phase 2, nurses, nurse practitioners, and physician experts representing all levels of newborn care participated in 4 e-Delphi surveys to develop the final draft of the TACT, which included 74 weighted characteristics.Implications For Practice and Research: Potential benefits of the TACT include improved communication across healthcare teams, reduced risk for readmission, and increased caregiver visitation. The next steps are to validate the TACT for use either retrospectively or in real time, including characteristic weights, before implementation of this tool in the clinical setting. [ABSTRACT FROM AUTHOR]