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15 results on '"Kunik, Vered"'

2. Refining the Phenotypic Spectrum of KMT5B-Associated Developmental Delay

Author

Eliyahu, Aviva, primary, Barel, Ortal, additional, Greenbaum, Lior, additional, Zaks Hoffer, Gal, additional, Goldberg, Yael, additional, Raas-Rothschild, Annick, additional, Singer, Amihood, additional, Bar-Joseph, Ifat, additional, Kunik, Vered, additional, Javasky, Elisheva, additional, Staretz-Chacham, Orna, additional, Pode-Shakked, Naomi, additional, Bazak, Lily, additional, Ruhrman-Shahar, Noa, additional, Pras, Elon, additional, Frydman, Moshe, additional, Shohat, Mordechai, additional, and Pode-Shakked, Ben, additional

Published
2022
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6. A transmissible RNA pathway in honey bees

Author

Maori, Eyal, primary, Garbian, Yael, additional, Kunik, Vered, additional, Mozes-Koch, Rita, additional, Malka, Osnat, additional, Kalev, Haim, additional, Sabath, Niv, additional, Sela, Ilan, additional, and Shafir, Sharoni, additional

Published
2018
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7. Whole-genome sequencing reveals principles of brain retrotransposition in neurodevelopmental disorders

Author

Jacob-Hirsch, Jasmine, primary, Eyal, Eran, additional, Knisbacher, Binyamin A, additional, Roth, Jonathan, additional, Cesarkas, Karen, additional, Dor, Chen, additional, Farage-Barhom, Sarit, additional, Kunik, Vered, additional, Simon, Amos J, additional, Gal, Moran, additional, Yalon, Michal, additional, Moshitch-Moshkovitz, Sharon, additional, Tearle, Rick, additional, Constantini, Shlomi, additional, Levanon, Erez Y, additional, Amariglio, Ninette, additional, and Rechavi, Gideon, additional

Published
2018
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8. Congenital Sucrase‐isomaltase Deficiency

Author

Haberman, Yael, primary, Di Segni, Ayelet, additional, Loberman‐Nachum, Nurit, additional, Barel, Ortal, additional, Kunik, Vered, additional, Eyal, Eran, additional, Kol, Nitzan, additional, Hout‐Siloni, Goni, additional, Kochavi, Brigitte, additional, Avivi, Camila, additional, Schvimer, Michael, additional, Rechavi, Gideon, additional, Anikster, Yair, additional, Barshack, Iris, additional, and Weiss, Batia, additional

Published
2017
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15. Motif extraction and protein classification.

Author

Kunik V, Solan Z, Edelman S, Ruppin E, and Horn D

Subjects
Amino Acid Sequence, Molecular Sequence Data, Proteins classification, Sequence Homology, Amino Acid, Algorithms, Amino Acid Motifs, Artificial Intelligence, Pattern Recognition, Automated methods, Proteins chemistry, Sequence Alignment methods, Sequence Analysis, Protein methods
Abstract

We present a novel unsupervised method for extracting meaningful motifs from biological sequence data. This de novo motif extraction (MEX) algorithm is data driven, finding motifs that are not necessarily over-represented in the data. Applying MEX to the oxidoreductases class of enzymes, containing approximately 7000 enzyme sequences, a relatively small set of motifs is obtained. This set spans a motif-space that is used for functional classification of the enzymes by an SVM classifier. The classification based on MEX motifs surpasses that of two other SVM based methods: SVMProt, a method based on the analysis of physical-chemical properties of a protein generated from its sequence of amino acids, and SVM applied to a Smith-Waterman distances matrix. Our findings demonstrate that the MEX algorithm extracts relevant motifs, supporting a successful sequence-to-function classification.

Published
2005
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