150 results on '"Kume, Hideaki"'
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2. Cleft Palate and Decreased Brain γ -aminobutyric Acid in Mice Lacking the 67-kDa Isoform of Glutamic Acid Decarboxylase
3. The Presenilin 2 Mutation (N141I) Linked to Familial Alzheimer Disease (Volga German Families) Increases the Secretion of Amyloid β Protein Ending at the 42nd (or 43rd) Residue
4. Discovery of Colorectal Cancer Biomarker Candidates by Membrane Proteomic Analysis and Subsequent Verification using Selected Reaction Monitoring (SRM) and Tissue Microarray (TMA) Analysis
5. Disease-Associated Mutations of TDP-43 Promote Turnover of the Protein Through the Proteasomal Pathway
6. A-to-I editing in the miRNA seed region regulates target mRNA selection and silencing efficiency
7. Aβ 11–40/42 production without γ-secretase ε-site cleavage
8. Galectin-7 as a potential biomarker of Stevens-Johnson syndrome/toxic epidermal necrolysis: identification by targeted proteomics using causative drug-exposed peripheral blood cells
9. Generative and discriminative model-based approaches to microscopic image restoration and segmentation
10. Impaired Ca2+ Store Functions in Skeletal and Cardiac Muscle Cells from Sarcalumenin-deficient Mice
11. Reticulons RTN3 and RTN4-B/C interact with BACE1 and inhibit its ability to produce amyloid β-protein
12. Cleft palate and decreased brain gamma-aminobutyric acid in mice lacking the 67-kDa isoform of glutamic acid decarboxylase
13. The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue
14. Mutant presenilin (A260V) affects Rab8 in PC12D cell
15. Norbin, a neurite-outgrowth-related protein, is a cytosolic protein localized in the somatodendritic region of neurons and distributed prominently in dendritic outgrowth in Purkinje cells
16. Quantitation of putative colorectal cancer biomarker candidates in serum extracellular vesicles by targeted proteomics
17. Abstract 2202: FABP5 in urinary extracellular vesicles is a potential biomarker of high Gleason score prostate cancer
18. MP99-01 PROTEOMIC ANALYSIS OF URINARY EXTRACELLULAR VESICLES FROM HIGH GLEASON SCORE PROSTATE CANCER
19. Proteomic analysis of urinary extracellular vesicles from high Gleason score prostate cancer
20. Casein kinase 1 is recruited to nuclear speckles by FAM83H and SON
21. Developmental genetic bases behind the independent origin of the tympanic membrane in mammals and diapsids
22. IGF-1 promotes β-amyloid production by a secretase-independent mechanism
23. A novel mechanism of keratin cytoskeleton organization through casein kinase Iα and FAM83H in colorectal cancer
24. In-depth Membrane Proteomic Study of Breast Cancer Tissues for the Generation of a Chromosome-based Protein List
25. A Strategy for Large-Scale Phosphoproteomics and SRM-Based Validation of Human Breast Cancer Tissue Samples
26. Strategy for SRM-based Verification of Biomarker Candidates Discovered by iTRAQ Method in Limited Breast Cancer Tissue Samples
27. Neuronal β‐amyloid generation is independent of lipid raft association of β‐secretase BACE1: analysis with a palmitoylation‐deficient mutant
28. Disease-associated mutations do not influence the subcellular localization of TDP-43 in neuronal cells
29. Clinical features of idiopathic restless legs syndrome in Japanese patients
30. The two-hydrophobic domain tertiary structure of reticulon proteins is critical for modulation of β-secretase BACE1
31. P3-320: Molecular mechanisms by which reticulon 3 regulates β-secretase BACE1
32. O2-03-08: Regulation of BACE1 function by Nogo-B/C and reticulon 3
33. Disturbance of cerebellar synaptic maturation in mutant mice lacking BSRPs, a novel brain-specific receptor-like protein family
34. Intracellular domain generation of amyloid precursor protein by ε-cleavage depends on C-terminal fragment by α-secretase cleavage
35. γ-Secretase can cleave amyloid precursor protein fragments independent of α- and β-secretase pre-cutting
36. Phosphorylation and spatiotemporal distribution of KW8 (NDRF/NeuroD2), a NeuroD family basic helix–loop–helix protein
37. Screening of Presenilin Binding Proteins
38. A Novel Brain Gene, Norbin, Induced by Treatment of Tetraethylammonium in Rat Hippocampal Slice and Accompanied with Neurite-Outgrowth in Neuro 2a Cells
39. 216 Production and characterization of mice devoid of the glutamic acid decarboxylase (67 kDa isoform-GAD67)
40. Processing of Alzheimer amyloid precursor protein in the transfected cells
41. Mice Lacking the 65 kDa Isoform of Glutamic Acid Decarboxylase (GAD65) Maintain Normal Levels of GAD67 and GABA in Their Brains but Are Susceptible to Seizures
42. Familial Alzheimer's Disease-Linked Mutations at Val717of Amyloid Precursor Protein Are Specific for the Increased Secretion of Aβ42(43)
43. A 11.5-kb 5′-Terminal cDNA Sequence of Chicken Breast Muscle Connectin/Titin Reveals Its Z Line Binding Region
44. Molecular Cloning of a Novel Basic Helix-Loop-Helix Protein from the Rat Brain
45. Molecular Cloning of a Partial cDNA Clone Encoding the C Terminal Region of Chicken Breast Muscle Connectin
46. Secretion of Alzheimer Amyloid β/A4 from Transfected Culture Cells.
47. 408 Different localization and release of GABA between neuroblastoma cells transfected with glutamic acid decarboxylase 65 and 67 genes
48. 818 Molecular cloning of a novel neurod family protein from rat brain
49. Localization of Three Fragments of Connectin in Chicken Breast Muscle Sarcomeres1
50. A Partial Connectin cDNA Encoding a Novel Type of RSP Motifs Isolated from Chicken Embryonic Skeletal Muscle1
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