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Background: The role of cytokines as a marker in the oral inflammatory process in ECC has not been fully explored before and after full mouth rehabilitation. Aims: The aim of this study was to assess the level of salivary interleukin-6 (IL-6) in children with ECC and to compare its levels before and after comprehensive full mouth rehabilitation. Methods and Materials: Saliva samples were collected from children with ECC prior to dental treatment and 3-month post treatment. The salivary IL-6 levels were analyzed using the ELISA method. The gingival index was also timely recorded. Oral health awareness sessions were conducted for children and their parents at regular intervals during the 3-month study period. Statistical analysis used: Wilcoxon Signed Rank test compared the levels of salivary IL-6 while, the paired t test compared the values of gingival index before and after treatment. Results: The mean level of salivary IL-6 before and 3 months after treatment had reduced and this reduction was statistically significant (P< 0.000). The gingival index scores had also reduced significantly 3-months post treatment (P< 0.002). Conclusions: Children with ECC when completely rehabilitated and kept under frequent follow up, which includes reinforcement of oral hygiene measures and maintaining a low caries activity state, the level of inflammation (IL-6) can definitely be minimized and thereby improving the quality of life of affected children.

Choanal atresia is a rare cryptic congenital anomaly with developmental failure of the nasal cavity to communicate with the nasophaynx, resulting in a significant physiological and anatomical alteration of the dento-facial complex. It is considered as a life-threatening or lethal congenital malformation in an obligatory nasal breathing neonate. Elective transnasal endoscopic repair is the most preferred and minimally invasive procedure to correct this anomaly. This case report describes the multi-disciplinary team approach that included pedodontists to manage the case of a 6-month-old infant with choanal atresia suffering from breathlessness, feeding difficulty, and disturbed sleep.

Background: Traumatic dental injury is highly variable in children, commonly involving the anterior segments of the maxilla and mandible. The management of such injuries is challenging owing to the anatomical differences and stages of development. The aim of treatment (usually non-invasive) should always be to achieve a stable occlusion with minimal functional impairment. Case Report: This case report describes the conservative management of a mandibular dentoalveolar fracture in a 5-year-old child. On extra-oral examination, abrasions were noticed in the chin region with moderate facial edema in the lower part of the face. Intra-oral examination revealed labial ecchymosis in the mandibular anterior region and a step deformity between the distal aspect of #72 and #82. The displaced dentoalveolar segment was repositioned with finger pressure, and a modified closed cap splint was cemented to the reduced fractured jaw. Follow-up visits at 3 weeks and 1 year showed satisfactory healing. Conclusion: The goal in treating pediatric fractures is to restore the underlying bony structure to its preinjury position as soon as possible. The treatment of choice should be minimally invasive and should restore occlusion with minimal residual esthetic and functional impairment. [ABSTRACT FROM AUTHOR]

Demineralization begins as a reversible process and current trends have surpassed the conventional options of invasive treatment to a more targeted non-invasive early management of reversible lesions using various new non-fluoride agents. Casein phosphopeptide-amorphous calcium phosphate is one such non-fluoride agent introduced with the potential of early remineralization in dental caries and dental erosion and to overcome conditions of dentine hypersensitivity. Various modifications of the agent have further expanded its applications in the dental field. This review was therefore, compiled from a final of 70 fulltext articles searched on PubMed and Google Scholar that had the specified MeSH terms, published in English from the year 2000-2020, to present an update on the innumerable applications and modifications of this agent in pediatric dental practice. [ABSTRACT FROM AUTHOR]

This is a case of swelling originating from dens invaginatus associated with lateral incisor, misdiagnosed as a globulomaxillary cyst. The initial diagnosis of globulomaxillary cyst was made solely from radiographs by observing a reverse pear-shaped radiolucency between the lateral incisor and cuspid. The results following pulp testing and Cone Beam Computed Tomography (CBCT) evaluation revealed the endodontic origin of the lesion, which entailed the treatment carried out by surgical enucleation and apicoectomy. This also details the clinical and diagnostic dilemma as well as conflicts associated with the diagnosis and management of the cystic lesion. [ABSTRACT FROM AUTHOR]

Introductio: Healing potential of plants is an age-old idea that has recently attained renewed interest. Considering the ineffectiveness, potentially harmful effects, and safety concerns of commonly used synthetic irrigants, the herbal alternatives for endodontic usage might prove to be advantageous.Aim: The aim of this study was to evaluate the adequacy of smear layer removal and cytotoxicity potential of triphala in comparison to sodium hypochlorite.Materials and Methods: The study was conducted in two parts: the first part of the study was cytotoxicity assessment studied using Alamar blue assay. L929 mouse fibroblasts were seeded in 96-well plates at a density of 5000 cells/well and treated with different concentrations of triphala and NaOCl for a period of 24 and 48 h. The percentage of cell viability was then quantified using an Alamar blue assay. The optical density was measured at 570 nm and compared with 620 nm, which was considered as a reference wavelength. The second part of the study was smear layer assessment at the coronal, middle, and apical third of twenty human premolar teeth using scanning electron microscope.Results: The Alamar blue reagent cytotoxicity study suggested that triphala showed no cytotoxic properties against the normal mouse fibroblast cells whereas sodium hypochlorite showed a significant cytotoxic effect against the L929 cell lines with the IC50 concentration at 1.8%, respectively, after the treatment of 24 h of incubation at 37°C temperature. Triphala was as effective as sodium hypochlorite in smear layer removal in the coronal and middle third of the root, but sodium hypochlorite showed better smear layer removal in the apical third.Conclusion: Triphala can be considered as a superior irrigant with good antibacterial efficacy and least cytotoxicity potential compared to conventional hypochlorite irrigating agent and provide adequate clearing of smear layer in the coronal and middle third, and further studies are warranted to alter the properties of liquid to make it more cleansable in the apical third of the root. [ABSTRACT FROM AUTHOR]

Aim: To clinically and radiographically evaluate the reparative dentin formation in indirect pulp treatment (IPT) using mineral trioxide aggregate (MTA) and light cured calcium silicate (TheraCal) in primary molars over a period of 6 months. Materials and Methods: A clinical trial on IPT on 43 primary molars in 21 patients between the age of 4-7 years, divided into two groups: 22 teeth in MTA group and 21 in TheraCal group. Measurement of the variation in dentin thickness was done on the digitalized radiograph at baseline, 3 months and 6 months using CorelDRAW X3 software. Results: Statistical analysis using an independent t-test for intragroup and intergroup comparison showed a significant increase in dentin thickness in both the MTA and TheraCal group (intragroup comparison [P < 0.05]). However, intergroup comparison between MTA and TheraCal showed no statistical difference in reparative dentin formation (P > 0.05). Conclusion: Clinically and radiographically, both MTA and TheraCal are good IPT materials. The better handling characteristics and comparable reparative dentin-forming ability of TheraCal make this material an alternative to MTA in pediatric restorative procedures. [ABSTRACT FROM AUTHOR]

Aim and Objective: This study aimed to investigate and compare compressive strength and flexural strength of self-cured Cention N with dual-cured Cention N., Materials and Methods: Cention N is mixed according to the proportions, as mentioned by the manufacturer. Dual cured samples are cured using a diode that emits blue light. Cylindrical plexiglass split mold of dimension 6 mm height, and 4 mm diameter used to fabricate samples for compressive strength. Compressive strength tested using Instron universal testing machine. Rectangular plexiglass split mold of dimension 25 mm length, 2 mm height, and 2 mm width were used to fabricate samples for flexural strength. Flexural strength tested using Instron universal testing machine. To compare the mean values independent t -test was used and the significance of the study was measured by calculating a p -value., Result: There is no statistically significant difference between compressive strength and flexural strength of self-cured Cention N with dual-cured Cention N., Conclusion: The type of polymerization does not affect flexural strength and compressive strength of Cention N., Clinical Significance: Self-curing polymerization alone is sufficient for Cention N to achieve adequate compressive strength and flexural strength. So it can be inserted as a single layer on a prepared cavity and to fasten curing additional light curing can be used., How to Cite This Article: Fousiya Ks, Balagopal VR, Suresh KJ, et al. Comparative Evaluation of Compressive Strength and Flexural Strength of Self-cured Cention N with Dual-cured Cention N: An In Vitro Study. Int J Clin Pediatr Dent 2022;15(2):210-214., Competing Interests: Source of support: Nil Conflict of interest: None, (Copyright © 2022; The Author(s).)

Introductio: Healing potential of plants is an age-old idea that has recently attained renewed interest. Considering the ineffectiveness, potentially harmful effects, and safety concerns of commonly used synthetic irrigants, the herbal alternatives for endodontic usage might prove to be advantageous., Aim: The aim of this study was to evaluate the adequacy of smear layer removal and cytotoxicity potential of triphala in comparison to sodium hypochlorite., Materials and Methods: The study was conducted in two parts: the first part of the study was cytotoxicity assessment studied using Alamar blue assay. L929 mouse fibroblasts were seeded in 96-well plates at a density of 5000 cells/well and treated with different concentrations of triphala and NaOCl for a period of 24 and 48 h. The percentage of cell viability was then quantified using an Alamar blue assay. The optical density was measured at 570 nm and compared with 620 nm, which was considered as a reference wavelength. The second part of the study was smear layer assessment at the coronal, middle, and apical third of twenty human premolar teeth using scanning electron microscope., Results: The Alamar blue reagent cytotoxicity study suggested that triphala showed no cytotoxic properties against the normal mouse fibroblast cells whereas sodium hypochlorite showed a significant cytotoxic effect against the L929 cell lines with the IC50 concentration at 1.8%, respectively, after the treatment of 24 h of incubation at 37°C temperature. Triphala was as effective as sodium hypochlorite in smear layer removal in the coronal and middle third of the root, but sodium hypochlorite showed better smear layer removal in the apical third., Conclusion: Triphala can be considered as a superior irrigant with good antibacterial efficacy and least cytotoxicity potential compared to conventional hypochlorite irrigating agent and provide adequate clearing of smear layer in the coronal and middle third, and further studies are warranted to alter the properties of liquid to make it more cleansable in the apical third of the root., Competing Interests: None

Aim: To evaluate and compare the efficacy of "calcium sucrose phosphate" (CaSP) toothpaste (Enafix 5%) with ordinarily used calcium, phosphate-containing toothpaste in elevating the level of calcium, phosphate ions in saliva. Secondary aims were to evaluate substantivity and plaque-reducing ability of CaSP toothpaste., Materials and Methods: Thirty study participants of age group 6-13 years were divided into two groups: Group X (Control group) was made to continue brushing with their regularly used calcium, phosphate-containing toothpaste and Group Y (Test group) was allotted CaSP toothpaste. 1 ml of unstimulated saliva was periodically collected from both groups to determine any alteration in the salivary calcium, phosphate level. Parameters such as substantivity and plaque-reducing ability of CaSP toothpaste were also evaluated. Salivary mineral's intergroup comparison was evaluated by Student's t -test while its intragroup comparison along with the plaque amount variation in Group Y was evaluated by ANOVA and Tukey's post hoc test., Results: Group Y showed an increase in the salivary calcium level though not statistically significant. The increase was pronounced in samples collected on day 1. Group Y showed a consistent level of calcium, phosphate in samples collected immediately and 6 h postbrushing, indicating its substantivity. In addition, Group Y had an impact in reducing the plaque level when the 1 st -month plaque score was compared with the 12 th -month score., Conclusion: CaSP leads to an increase in the salivary calcium level though it was not statistically significant. Supervised brushing and dietary habits showed a positive effect on both the groups. CaSP toothpaste also showed substantivity and plaque-reducing ability., Competing Interests: There are no conflicts of interest.