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Background: Anal fissures are most caused by damage to the lining of the anus or anal canal, the last part of the large intestine. Most cases occur in people who have constipation when a particularly hard or large stool tears the lining of the anal canal. Postoperative pain relief especially using analgesic drugs with minimal side effects has considerable clinical importance. Aim: - This study was undertaken to compare the role of paracetamol and diclofenac sodium in post-anal fissure surgery pain. Materials and Methods: A prospective study was conducted at NCMCH, Panipat This study included 50 patients who were admitted to IPD, and underwent anal fissure surgery at age 25-60 years. All measurements were performed using standard methods in the literature. A visual analog scale was used to assess the pain score. Side effects of drugs were noted. Results: The study results confirm that Paracetamol was more effective in the management of post-surgical pain. We divided 50 patients into two groups. Group 1 was treated for the management of post-surgical pain with diclofenac sodium and Group 2 with paracetamol. Our findings revealed a statistically significant improvement of 85% in Group 2 as compared to Group 1. Conclusion: - In conclusion, the agent PCM to be used for the management of postoperative anal fissure surgical pain is desired to relieve the pain effectively. [ABSTRACT FROM AUTHOR]

Background: Amoebiasis is parasitic infection occur due to protozoan parasite, Entamoeba histolytica in human being. It commonly resides in large intestine but can invade to other organs Amoebic Liver Abscess (ALA) is the most common complication of invasive amoebiasis. Aim and Objective: The present study was planned to determine the demographic profile and symptoms of liver abscess with Iron deficiency Anemia. Materials and Method: The present study was conducted on 50 confirmed liver abscess cases on the basis of radiological images, which were above 20 years of age were considered for the study. The estimations of the hemoglobin, serum ferritin, serum iron, and total iron-binding capacity (TIBC) by cell counter and ELISA method. Results: The study has shown that the value of mean and standard division serum ferritin (11.17 ± 2.57), serum Iron (42.45 ± 3.69), MCV (79.69 ± 21.57), and Hb (12.11 ±1.67) is significantly low as compared to serum TIBC (816 ± 155.19) in liver abscess patient. Conclusion: ALA presents itself through various non-specific symptoms and signs. Confirmation of the diagnosis is made possible with the help of radiological and microbiological attributes. Early diagnosis and prompt iron profile treatment may decline the overall mortality/morbidity associated with the disease. [ABSTRACT FROM AUTHOR]