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11 results on '"Kumakura, Tetsuo"'

1. Effects of the Great East Japan Earthquake and the Fukushima Daiichi Nuclear Power Plant accident on behavioural and psychological symptoms of dementia among patients

Author

Miyagawa, Akemi, primary, Kunii, Yasuto, additional, Gotoh, Daisuke, additional, Hoshino, Hiroshi, additional, Kakamu, Takeyasu, additional, Hidaka, Tomoo, additional, Kumakura, Tetsuo, additional, Fukushima, Tetsuhito, additional, Yabe, Hirooki, additional, and Kawakatsu, Shinobu, additional

Published
2021
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2. Differential diagnosis of memory impairment in areas affected by a natural disaster: a case report

Author

Miyagawa, Akemi, Kunii, Yasuto, Gotoh, Daisuke, Ito, Masashi, Itagaki, Shuntaro, Matsumoto, Takatomo, Kumakura, Tetsuo, Yabe, Hirooki, Miyagawa, Akemi, Kunii, Yasuto, Gotoh, Daisuke, Ito, Masashi, Itagaki, Shuntaro, Matsumoto, Takatomo, Kumakura, Tetsuo, and Yabe, Hirooki

Abstract

type:Text, We treated a man with a chief complaint of memory impairment after the Great East Japan Earthquake. Initially, he was diagnosed with dementia. However, after several tests, neither could a definitive diagnosis of dementia be reached, nor was there any apparent evidence for depression, epilepsy, delirium, or internal medicine diseases. During the earthquake, the patient experienced the severe trauma of watching his wife being swept away by a tsunami. Furthermore, he experienced separation from his family. Because of this traumatic experience, we suspected that dissociative disorder was involved in the development of the memory impairment and thus, we switched to treatments focusing on emotional support. Subsequently, the patient's memory impairment gradually improved. The present case demonstrates the importance of considering dissociative disorders when examining a patient with memory impairment in areas affected by disasters.

Published
2021

4. Hospital Staff Shortage after the 2011 Triple Disaster in Fukushima, Japan-An Earthquake, Tsunamis, and Nuclear Power Plant Accident: A Case of the Soso District

Author

Ochi, Sae, primary, Tsubokura, Masaharu, additional, Kato, Shigeaki, additional, Iwamoto, Shuichi, additional, Ogata, Shinichi, additional, Morita, Tomohiro, additional, Hori, Arinobu, additional, Oikawa, Tomoyoshi, additional, Kikuchi, Antoku, additional, Watanabe, Zenjiro, additional, Kanazawa, Yukio, additional, Kumakawa, Hiromi, additional, Kuma, Yoshinobu, additional, Kumakura, Tetsuo, additional, Inomata, Yoshimitsu, additional, Kami, Masahiro, additional, Shineha, Ryuzaburo, additional, and Saito, Yasutoshi, additional

Published
2016
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5. A microsatellite repeat in the promoter of the N-methyl-d-aspartate receptor 2A subunit (GRIN2A) gene suppresses transcriptional activity and correlates with chronic outcome in schizophrenia

Author

Itokawa, Masanari, primary, Yamada, Kazuo, additional, Yoshitsugu, Kiyoshi, additional, Toyota, Tomoko, additional, Suga, Toshiro, additional, Ohba, Hisako, additional, Watanabe, Akiko, additional, Hattori, Eiji, additional, Shimizu, Hiromitsu, additional, Kumakura, Tetsuo, additional, Ebihara, Mitsuru, additional, Meerabux, Joanne MA, additional, Toru, Michio, additional, and Yoshikawa, Takeo, additional

Published
2003
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7. Prosthetic Treatment for Psychiatric Patients.

Author

Masuda, Takayuki, primary, Yoshida, Keiichi, additional, Kasuta, Sanae, additional, Tsuchida, Yukihiro, additional, Kohno, Shouji, additional, Tabata, Tsuneo, additional, Kumakura, Tetsuo, additional, and Enguchi, Hiroshi, additional

Published
1994
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10. A microsatellite repeat in the promoter of the NmethylDaspartate receptor 2A subunit GRIN2Agene suppresses transcriptional activity and correlates with chronic outcome in schizophrenia

Author

Itokawa, Masanari, Yamada, Kazuo, Yoshitsugu, Kiyoshi, Toyota, Tomoko, Suga, Toshiro, Ohba, Hisako, Watanabe, Akiko, Hattori, Eiji, Shimizu, Hiromitsu, Kumakura, Tetsuo, Ebihara, Mitsuru, Meerabux, Joanne M.A., Toru, Michio, and Yoshikawa, Takeo

Abstract

Hypofunction of theNmethylDaspartate NMDA receptor has been hypothesized to underlie the pathophysiology of schizophrenia, based on the observation that noncompetitive antagonists of the NMDA receptor, such as phencyclidine, induce schizophrenialike symptoms. Mice lacking the NR2A subunit of the NMDA receptor complex are known to display abnormal behaviour, similar to schizophrenic symptoms. The expression of NR2A starts at puberty, a period corresponding to the clinical onset of schizophrenia. This evidence suggests that the NR2A GRIN2Agene may play a role in the development of schizophrenia and disease phenotypes. In this study, we performed a genetic analysis of this gene in schizophrenia. Analysis of theGRIN2Agene detected four single nucleotide polymorphisms, and a variable GTnrepeat in the promoter region of the gene. A casecontrol study 375 schizophrenics and 378 controls demonstrated evidence of an association between the repeat polymorphism and the disease P0.05, MannWhitney test, with longer alleles overly represented in patients. An invitro promoter assay revealed a length dependent inhibition of transcriptional activity by the GTnrepeat, which was consistent with a receptor binding assay in postmortem brains. Significantly, the score of symptom severity in chronic patients correlated with repeat size P0.01, Spearman's Rank test. These results illustrate a genotypephenotype correlation in schizophrenia and suggest that the longer GTnstretch may act as a riskconferring factor that worsens chronic outcome by reducing GRIN2A levels in the brain.

Published
2003
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11. Differential diagnosis of memory impairment in areas affected by a natural disaster:a case report.

Author

Miyagawa A, Kunii Y, Gotoh D, Ito M, Itagaki S, Matsumoto T, Kumakura T, and Yabe H

Subjects
Diagnosis, Differential, Humans, Japan, Male, Tsunamis, Disasters, Earthquakes, Natural Disasters
Abstract

We treated a man with a chief complaint of memory impairment after the Great East Japan Earthquake. Initially, he was diagnosed with dementia. However, after several tests, neither could a definitive diagnosis of dementia be reached, nor was there any apparent evidence for depression, epilepsy, delirium, or internal medicine diseases. During the earthquake, the patient experienced the severe trauma of watching his wife being swept away by a tsunami. Furthermore, he experienced separation from his family. Because of this traumatic experience, we suspected that dissociative disorder was involved in the development of the memory impairment and thus, we switched to treatments focusing on emotional support. Subsequently, the patient's memory impairment gradually improved. The present case demonstrates the importance of considering dissociative disorders when examining a patient with memory impairment in areas affected by disasters.

Published
2021
Full Text
View/download PDF

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