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2. National prevalence of vision impairment and blindness and associated risk factors in adults aged 40 years and older with known or undiagnosed diabetes: results from the SMART-India cross-sectional study

Author

Bhende, Pramod, Surya, Janani, Gopal, Lingam, Ramakrishnan, Radha, Roy, Rupak, Das, Supita, Manayath, George, Prabhakaran, Vignesh T, Anantharaman, Giridhar, Gopalakrishnan, Mahesh, Natarajan, Sundaram, Krishnan, Radhika, Mani, Sheena Liz, Agarwal, Manisha, Behera, Umesh, Bhattacharjee, Harsha, Barman, Manabjyoti, Sen, Alok, Saxena, Moneesh, Sil, Asim K, Chakabarty, Subhratanu, Cherian, Thomas, Jitesh, Reesha, Naigaonkar, Rushikesh, Desai, Abishek, Kulkarni, Sucheta, Mohan, Deepa, Chawla, Gajendra, Gurudas, Sarega, Vasconcelos, Joana C, Prevost, A Toby, Raman, Rajiv, Rajalakshmi, Ramachandran, Ramasamy, Kim, Mohan, Viswanathan, Rani, Padmaja K, Das, Taraprasad, Conroy, Dolores, Tapp, Robyn J, and Sivaprasad, Sobha

Published
2024
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3. Natural course of non-center-involving diabetic macular edema progression in patients under initial observation

Author

Pradhana, Divya, Priya, N., Manayath, George, Kulkarni, Sucheta, Behera, Umesh, Agarwal, Tushar, Agarwal, Manisha, Shah, Shalin, Giridhar, A., Surya, Janani, Ramasamy, Kim, Vignesh, T., Shoba, Sivaprasad, Bhende, Muna, and Raman, Rajiv

Subjects
Dropsy -- Care and treatment -- Development and progression -- Risk factors, Diabetes therapy, Edema -- Care and treatment -- Development and progression -- Risk factors, Type 2 diabetes -- Care and treatment -- Development and progression -- Risk factors, Evidence-based medicine, Health
Abstract

Byline: Divya. Pradhana, N. Priya, George. Manayath, Sucheta. Kulkarni, Umesh. Behera, Tushar. Agarwal, Manisha. Agarwal, Shalin. Shah, A. Giridhar, Janani. Surya, Kim. Ramasamy, T. Vignesh, Sivaprasad. Shoba, Muna. Bhende, Rajiv. [...]

Published
2024

4. Effective refractive error coverage in adults aged 50 years and older: estimates from population-based surveys in 61 countries

Author

Bron, Alain, Cheng, Ching-Yu, Fernandes, Arthur, Friedman, David, Gazzard, Andrew, Kahloun, Rim, Kempen, John, Khairallah, Moncef, Lansingh, Van C, Leasher, Janet, Leveziel, Nicolas, Limburg, Hans, Nowak, Michal, Pesudovs, Konrad, Peto, Tunde, Rossetti, Luca, Tahhan, Nina, Varma, Rohit, Alemayehu, Wondu, Arditi, Aries, Dana, Reza, Del Monte, Monte, Deva, jenny, Dreer, Laura, Ehrlich, Josh, Ellwein, Leon, Hammond, Billy, Hartnett, Mary E, Ingram, April, Khanna, Rohit, Kim, Judy, Lim, Jennifer, Morse, Alan, Musch, David, Parodi, Maurizio B, Ramulu, Pradeep, Robin, Alan, Serle, Janet, Shen, Tueng, Sitorus, Rita S, Stambolian, Dwight, Topouzis, Fotis, Tsilimbaris, Miltiadis, Virgili, Gianni, West, Sheila, Ababora, Jafer K, AlSawahli, Heba, Andriamanjato, Hery Harimanitra, Barrenechea, Rosario, Batlle, Juan F, Burnett, Anthea M, Finger, Robert P, Gallarreta, Marcelo, Gomez-Bastar, Pedro A, Gurung, Reeta, Jain, Elesh, Kabona, George E, Kalua, Khumbo, Kandeke, Levi, Karimurio, Jefitha, Kikira, Susan A, Kulkarni, Sucheta, Mathenge, Wanjiku, Mishra, Sailesh Kumar, Mohammadi, Seyed Farzad, Mörchen, Manfred, Muhammad, Nasiru, Mutati, Grace C, Nano, Maria Eugenia, Németh, János, Paduca, Ala, Páez, Alexander, Rabiu, M Mansur, Rif'ati, Lutfah, Salowi, Mohamad Aziz, Sapkota, Yuddha D, Sargent, Nicholas, Thoufeeq, Ubeydulla, Villalobos, Astrid V, Xiao, Biaxiang, Yee Melgar, Mariano, Zhang, Xiu Juan, Bourne, Rupert Richard Alexander, Cicinelli, Maria Vittoria, Sedighi, Tabassom, Tapply, Ian H, McCormick, Ian, Jonas, Jost B, Congdon, Nathan G, Ramke, Jacqueline, Naidoo, Kovin S, Fricke, Timothy R, Burton, Matthew J, Müller, Andreas, Bikbov, Mukharram M, Furtado, João M, Kyari, Fatima, He, Mingguang, Wang, Ya Xing, Vijaya, Lingam, Nangia, Vinay, Brian, Garry, Emamian, Mohammad Hassan, Fotouhi, Akbar, Hashemi, Hassan, Khandekar, Rajiv B, Marmamula, Srinivas, Salomão, Solange, George, Ronnie, Kazakbaeva, Gyulli, Braithwaite, Tasanee, Casson, Robert J, Iwase, Aiko, Gupta, Noopur, Abdianwall, Mohammad H, Wong, Tien Y, Wang, Ningli, Taylor, Hugh R, Flaxman, Seth R, Keel, Stuart, and Resnikoff, Serge

Published
2022
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5. Effective cataract surgical coverage in adults aged 50 years and older: estimates from population-based surveys in 55 countries

Author

Ababora, Jafer K, AlSawahli, Heba, Alvarado, Doris M, Andriamanjato, Hery Harimanitra, Ashraf Amalius, Ahmad, Barrenechea, Rosario, Batlle, Juan F, Brea, Ileana, Burnett, Anthea M, Chiriboga, Felipe A, Davaatseren, Uranchimeg, Duerksen, Rainald, Eusebio, Cristina I, Finger, Robert P, Gomez-Bastar, Pedro A, Gonzales, César, Gurung, Reeta, Hajar, Saad, Jadoon, Muhammad Zahid, Jain, Elesh, Kabona, George E, Kalua, Khumbo, Kandeke, Levi, Kandel, Ram P, Karimurio, Jefitha, Kulkarni, Sucheta, Lansingh, Van C, Lepcha, Nor T, Mathenge, Wanjiku, Mishra, Sailesh Kumar, Mohammadi, Seyed Farzad, Mörchen, Manfred, Muhammad, Nasiru, Musana, Paddy B, Mutati, Grace C, Nano, Maria Eugenia, Németh, János, Paduca, Ala, Páez, Alexander, Polack, Sarah, Rabiu, M Mansur, Rif'ati, Lutfah, Rodríguez Rodríguez, Beatriz Natividad, Salowi, Mohamad Aziz, Sapkota, Yuddha D, Sargent, Nicholas, Syumarti, Mansyur, Thoufeeq, Ubeydulla, Villalobos, Astrid V, Wachira, Joseph W, Wu, Min, Xiao, Biaxiang, Yee Melgar, Mariano, Zhang, Xiu Juan, McCormick, Ian, Butcher, Robert, Evans, Jennifer R, Mactaggart, Islay Z, Limburg, Hans, Jolley, Emma, Oye, Joseph Enyegue, Bastawrous, Andrew, Furtado, João M, Joshi, Anagha, Xiao, Baixiang, Ravilla, Thulasiraj D, Bourne, Rupert R A, Cieza, Alarcos, Keel, Stuart, Burton, Matthew J, and Ramke, Jacqueline

Published
2022
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6. Prevalence of diabetic retinopathy in India stratified by known and undiagnosed diabetes, urban–rural locations, and socioeconomic indices: results from the SMART India population-based cross-sectional screening study

Author

Bhende, Pramod, Surya, Janani, Gopal, Lingam, Ramakrishnan, Radha, Roy, Rupak, Das, Supita, Manayath, George, Pooleeswaran, Vignesh T, Anantharaman, Giridhar, Gopalakrishnan, Mahesh, Natarajan, Sundaram, Krishnan, Radhika, Mani, Sheena Liz, Agarwal, Manisha, Behera, Umesh, Bhattacharjee, Harsha, Barman, Manabjyoti, Sen, Alok, Saxena, Moneesh, Sil, Asim K, Chakrabarty, Subhratanu, Cherian, Thomas, Jitesh, Reesha, Naigaonkar, Rushikesh, Desai, Abishek, Kulkarni, Sucheta, Raman, Rajiv, Vasconcelos, Joana C, Rajalakshmi, Ramachandran, Prevost, A Toby, Ramasamy, Kim, Mohan, Viswanathan, Mohan, Deepa, Rani, Padmaja K, Conroy, Dolores, Das, Taraprasad, and Sivaprasad, Sobha

Published
2022
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7. HER3 targeting potentiates growth suppressive effects of the PI3K inhibitor BYL719 in pre-clinical models of head and neck squamous cell carcinoma.

Author

Meister, Kara S, Godse, Neal R, Khan, Nayel I, Hedberg, Matthew L, Kemp, Carolyn, Kulkarni, Sucheta, Alvarado, Diego, LaVallee, Theresa, Kim, Seungwon, Grandis, Jennifer R, and Duvvuri, Umamaheswar

Subjects
Cell Line, Tumor, Animals, Humans, Mice, Thiazoles, Receptor, erbB-3, Xenograft Model Antitumor Assays, Signal Transduction, Cell Proliferation, Up-Regulation, Drug Synergism, Proto-Oncogene Proteins c-akt, Phosphatidylinositol 3-Kinases, Molecular Targeted Therapy, Squamous Cell Carcinoma of Head and Neck, Phosphoinositide-3 Kinase Inhibitors, Receptor, ErbB-3, Cell Line, Tumor, Receptor, ErbB-3
Abstract

BYL719 is a PI3K inhibitor that has demonstrated efficacy in the treatment of head and neck squamous cell carcinoma. BYL719 exerts its therapeutic effect by suppressing AKT and other proliferative signaling mechanisms. Despite PI3K inhibition and AKT suppression, residual activity of protein S6, a core marker of proliferative activation, has been observed. HER3, either via dimerization or activation by its ligand neurgeulin (NRG), is known to activate PI3K. Thus, we hypothesized that co-targeting HER3 and PI3K would lead to greater suppression of the PI3K-AKT signaling pathway and greater tumor suppression than with BYL719 alone. We investigated biochemical expression and activation of the HER3-PI3K-AKT-S6 pathway in HNSCC cell lines and patient-derived xenografts (PDXs). Antitumor effects of HER3 and PI3K inhibitors alone and in combination were evaluated in cell culture and murine models. Treatment of HNSCC cell lines with BYL719 significantly reduced AKT activation and suppressed tumor growth. However, S6 was persistently activated despite suppression of AKT. Combination treatment with KTN3379, a monoclonal antibody targeted against HER3, and BYL719 led to enhanced suppression of in vitro and in vivo cancer growth and durable suppression of AKT and S6. Therefore, inhibition of HER3 with KTN3379 enhanced the effects of PI3K inhibition in pre-clinical HNSCC models. These data support co-targeting HER3 and PI3K for the treatment of HSNCC.

Published
2019

9. National prevalence of vision impairment and blindness and associated risk factors in adults aged 40 years and older with known or undiagnosed diabetes: results from the SMART-India cross-sectional study

Author

Gurudas, Sarega, primary, Vasconcelos, Joana C, additional, Prevost, A Toby, additional, Raman, Rajiv, additional, Rajalakshmi, Ramachandran, additional, Ramasamy, Kim, additional, Mohan, Viswanathan, additional, Rani, Padmaja K, additional, Das, Taraprasad, additional, Conroy, Dolores, additional, Tapp, Robyn J, additional, Sivaprasad, Sobha, additional, Bhende, Pramod, additional, Surya, Janani, additional, Gopal, Lingam, additional, Ramakrishnan, Radha, additional, Roy, Rupak, additional, Das, Supita, additional, Manayath, George, additional, Prabhakaran, Vignesh T, additional, Anantharaman, Giridhar, additional, Gopalakrishnan, Mahesh, additional, Natarajan, Sundaram, additional, Krishnan, Radhika, additional, Mani, Sheena Liz, additional, Agarwal, Manisha, additional, Behera, Umesh, additional, Bhattacharjee, Harsha, additional, Barman, Manabjyoti, additional, Sen, Alok, additional, Saxena, Moneesh, additional, Sil, Asim K, additional, Chakabarty, Subhratanu, additional, Cherian, Thomas, additional, Jitesh, Reesha, additional, Naigaonkar, Rushikesh, additional, Desai, Abishek, additional, Kulkarni, Sucheta, additional, Mohan, Deepa, additional, and Chawla, Gajendra, additional

Published
2024
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12. TMEM16A/ANO1 suppression improves response to antibody‐mediated targeted therapy of EGFR and HER2/ERBB2

Author

Kulkarni, Sucheta, Bill, Anke, Godse, Neal R, Khan, Nayel I, Kass, Jason I, Steehler, Kevin, Kemp, Carolyn, Davis, Kara, Bertrand, Carol A, Vyas, Avani R, Holt, Douglas E, Grandis, Jennifer R, Gaither, L Alex, and Duvvuri, Umamaheswar

Subjects
Biomedical and Clinical Sciences, Oncology and Carcinogenesis, Breast Cancer, Cancer, Biotechnology, Rare Diseases, 2.1 Biological and endogenous factors, Aetiology, Animals, Anoctamin-1, Breast Neoplasms, Carcinoma, Squamous Cell, Cell Line, Tumor, Cetuximab, Chloride Channels, Chromosomes, Human, Pair 11, ErbB Receptors, Female, Head and Neck Neoplasms, Humans, Mice, Mice, Nude, Neoplasm Proteins, Receptor, ErbB-2, Squamous Cell Carcinoma of Head and Neck, Trastuzumab, Receptor, erbB-2, Oncology & Carcinogenesis, Genetics, Oncology and carcinogenesis
Abstract

TMEM16A, a Ca2+ -activated Cl- channel, contributes to tumor growth in breast cancer and head and neck squamous cell carcinoma (HNSCC). Here, we investigated whether TMEM16A influences the response to EGFR/HER family-targeting biological therapies. Inhibition of TMEM16A Cl- channel activity in breast cancer cells with HER2 amplification induced a loss of viability. Cells resistant to trastuzumab, a monoclonal antibody targeting HER2, showed an increase in TMEM16A expression and heightened sensitivity to Cl- channel inhibition. Treatment of HNSCC cells with cetuximab, a monoclonal antibody targeting EGFR, and simultaneous TMEM16A suppression led to a pronounced loss of viability. Biochemical analyses of cells subjected to TMEM16A inhibitors or expressing chloride-deficient forms of TMEM16A provide further evidence that TMEM16A channel function may play a role in regulating EGFR/HER2 signaling. These data demonstrate that TMEM16A regulates EGFR and HER2 in growth and survival pathways. Furthermore, in the absence of TMEM16A cotargeting, tumor cells may acquire resistance to EGFR/HER inhibitors. Finally, targeting TMEM16A improves response to biological therapies targeting EGFR/HER family members.

Published
2017

13. Social determinants of diabetic retinopathy and impact of sight-threatening diabetic retinopathy: A study from Pune, India

Author

Kulkarni, Sucheta, Patil, Veena, Kashikar, Rashmi, Deshpande, Rahul, and Dole, Kuldeep

Subjects
Blindness -- Risk factors -- Prevention, Diabetic retinopathy -- Diagnosis -- Care and treatment, Health care disparities -- Demographic aspects -- Social aspects -- Economic aspects, Health
Abstract

Byline: Sucheta. Kulkarni, Veena. Patil, Rashmi. Kashikar, Rahul. Deshpande, Kuldeep. Dole Purpose: Diabetes-related retinopathy is the leading cause of blindness in India. The study was carried out with the purpose [...]

Published
2023

14. Natural course of non-center-involving diabetic macular edema progression in patients under initial observation

Author

Pradhana, Divya, primary, Priya, N Swathi, additional, Manayath, George J, additional, Kulkarni, Sucheta, additional, Behera, Umesh C, additional, Agarwal, Tushar, additional, Agarwal, Manisha, additional, Shah, Shalin, additional, Giridhar, A, additional, Surya, Janani, additional, Ramasamy, Kim, additional, Vignesh, TP, additional, Shoba, Sivaprasad, additional, Bhende, Muna, additional, and Raman, Rajiv, additional

Published
2023
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15. Data from Genetic Dissociation of Glycolysis and the TCA Cycle Affects Neither Normal nor Neoplastic Proliferation

Author

Jackson, Laura E., primary, Kulkarni, Sucheta, primary, Wang, Huabo, primary, Lu, Jie, primary, Dolezal, James M., primary, Bharathi, Sivakama S., primary, Ranganathan, Sarangarajan, primary, Patel, Mulchand S., primary, Deshpande, Rahul, primary, Alencastro, Frances, primary, Wendell, Stacy G., primary, Goetzman, Eric S., primary, Duncan, Andrew W., primary, and Prochownik, Edward V., primary

Published
2023
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16. Fig S1-6, Table S1 from Genetic Dissociation of Glycolysis and the TCA Cycle Affects Neither Normal nor Neoplastic Proliferation

Author

Jackson, Laura E., primary, Kulkarni, Sucheta, primary, Wang, Huabo, primary, Lu, Jie, primary, Dolezal, James M., primary, Bharathi, Sivakama S., primary, Ranganathan, Sarangarajan, primary, Patel, Mulchand S., primary, Deshpande, Rahul, primary, Alencastro, Frances, primary, Wendell, Stacy G., primary, Goetzman, Eric S., primary, Duncan, Andrew W., primary, and Prochownik, Edward V., primary

Published
2023
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18. Harnessing Generalizable Real World Ophthalmic Big Data: A Descriptive Analysis of the Bodhya Eye Consortium Model for Collaborative Research (Preprint)

Author

Sood, Ishaana, primary, Sabherwal, Shalinder, additional, Mathur, Umang, additional, Jain, Elesh, additional, Bhadauria, Madhu, additional, Agrawal, Deepshikha, additional, Khurana, Ashi, additional, Mittal, Vikas, additional, Mahindrakar, Avinash, additional, Govindahari, Vishal, additional, Kulkarni, Sucheta, additional, and Nischal, Ken K, additional

Published
2023
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19. Harnessing Generalizable Real World Ophthalmic Big Data: The Bodhya Eye Consortium Model for Collaborative Research (Preprint)

Author

Sood, Ishaana, primary, Sabherwal, Shalinder, additional, Mathur, Umang, additional, Jain, Elesh, additional, Bhadauria, Madhu, additional, Agrawal, Deepshikha, additional, Khurana, Ashi, additional, Mittal, Vikas, additional, Mahindrakar, Avinash, additional, Govindahari, Vishal, additional, Kulkarni, Sucheta, additional, and Nischal, Ken K, additional

Published
2023
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20. Comparative study of anatomical and functional recovery of eye along with patient satisfaction score after small-incision cataract surgery and phacoemulsification cataract surgery

Author

Dole, Kuldeep, Baheti, Neha, Deshpande, Rahul, Kulkarni, Sucheta, Shetty, Rakesh, and Deshpande, Madan

Subjects
Patient satisfaction -- Evaluation, Cataract -- Surgery, Health
Abstract

Byline: Kuldeep. Dole, Neha. Baheti, Rahul. Deshpande, Sucheta. Kulkarni, Rakesh. Shetty, Madan. Deshpande Purpose: Functional recovery after cataract surgery depends on the anatomical recovery of the eye. This study compared [...]

Published
2022

22. The impact of early intervention on a child with vision loss in infancy - A parental perspective

Author

Kulkarni, Sucheta, Veer, Amrapali, Gaikwad, Ashwini, and Deshpande, Madan

Subjects
Vision disorders in children -- Diagnosis -- Care and treatment, Child development -- Health aspects -- Physiological aspects, Health
Abstract

Byline: Sucheta. Kulkarni, Amrapali. Veer, Ashwini. Gaikwad, Madan. Deshpande Purpose: To assess the impact of early intervention services provided to children with visual loss and to report how parents perceive [...]

Published
2022

23. Commentary: Population-based assessment of barriers for the uptake of eye care services among elderly people: Findings from rapid assessment of visual impairment studies from Telangana, India

Author

Kulkarni, Sucheta

Subjects
Telangana, India -- Research, Medical care -- Utilization, Aged -- Care and treatment -- Research, Vision disorders -- Care and treatment -- Research, Health care disparities -- Research, Health
Abstract

Byline: Sucheta. Kulkarni Visual impairment (VI) does have an impact on the quality of life and can interfere with the day-to-day activities of the affected individual. Global prevalence of VI [...]

Published
2022

25. Common eye conditions in children: care and referral at primary level.

Author

Kulkarni, Sucheta and Ademola-Popoola, Dupe

Subjects
*INFANT care, *GLAUCOMA, *LACRIMAL apparatus, *EYE care, *OPERATIVE surgery, *OPHTHALMOLOGISTS, *EYE abnormalities, *MEDICATION therapy management, *EYE infections, *MEDICAL referrals, *RETINOBLASTOMA, *EYE diseases, *CONJUNCTIVITIS
Published
2023

27. Visual impairment and blindness among children from schools for the blind in Maharashtra state, India: Changing trends over the last decade

Author

Kulkarni, Sucheta, Gilbert, Clare, Giri, Nilesh, Hankare, Pravin, Dole, Kuldeep, and Deshpande, M.

Subjects
Vision disorders in children -- Statistics -- Causes of, Blindness -- Causes of -- Statistics, Elementary school students -- Health aspects -- Physiological aspects, Pediatric research, Health
Abstract

Byline: Sucheta. Kulkarni, Clare. Gilbert, Nilesh. Giri, Pravin. Hankare, Kuldeep. Dole, M. Deshpande Purpose: To determine the causes of severe visual impairment and blindness in children in schools for the [...]

Published
2022

28. Cost analysis of pediatric cataract surgery in a tertiary eye care hospital in Western India

Author

Kapse, Rajesh, Agarwal, Stuti, Rishikeshi, Nikhil, Deshpande, Madan, Kulkarni, Sucheta, Deshpand, Rahul, and Dole, Kuldeep

Subjects
Vision disorders in children -- Risk factors -- Diagnosis -- Care and treatment, Blindness -- Causes of, Medical care, Cost of -- Analysis, Cataract -- Surgery, Intraocular lenses -- Patient outcomes, Health
Abstract

Byline: Rajesh. Kapse, Stuti. Agarwal, Nikhil. Rishikeshi, Madan. Deshpande, Sucheta. Kulkarni, Rahul. Deshpand, Kuldeep. Dole Purpose: To assess the cost of pediatric cataract surgery in a tertiary eye care hospital [...]

Published
2022

31. Exploring the barriers for eye care among transgenders and commercial sex workers in Pune, Maharashtra

Author

Kulkarni, Sucheta, Lawande, Devika, Dharmadhikari, Sheetal, and Deshpande, Col

Subjects
Discrimination in medical care, Vision disorders -- Care and treatment -- Social aspects, Transgender people -- Care and treatment -- Social aspects, Prostitutes -- Care and treatment -- Social aspects, Health
Abstract

Byline: Sucheta. Kulkarni, Devika. Lawande, Sheetal. Dharmadhikari, Col. Deshpande Purpose: To explore all possible barriers faced by transgenders (TG) and commercial sex workers (CSW) in accessing eye care in Pune [...]

Published
2021

32. A comparative clinical study of postoperative care by teleophthalmology and in-person consultation at hospital outpatient department after an uncomplicated cataract surgery.

Author

Dole, Kuldeep, Pakhale, Sneha, Gandhi, Anuprita, Deshpande, Madan, Deshpande, Rahul, and Kulkarni, Sucheta

Subjects
PHACOEMULSIFICATION, CATARACT surgery, POSTOPERATIVE care, PATIENT satisfaction, VISUAL acuity, EYE care
Abstract

BACKGROUND: Teleophthalmology provides an opportunity to conduct consultations in far-flung and remote areas that have no access to specialized eye care. However, there is a paucity of studies to assess the effect of missing in-person follow-up on initial postoperative visits. The study thus aims to compare postoperative satisfaction and uncorrected distance visual activity after an uneventful phacoemulsification cataract surgery in patients with teleconsultation approach to those with hospital visit. MATERIALS AND METHODS: The prospective observation study (n = 240) was conducted in patients who underwent surgery for cataract. Pre- and post-operative data were collected and divided into two groups based on the type of postoperative follow-up. All patients were scheduled for ophthalmic reviews in the hospital on day 1, day 7, and day 30-40 (hospital visit group) or through teleconsultation on days 1 and 7 followed by a hospital visit on days 30-40 (teleconsultation group). Outcomes evaluated in both groups were complications, patient satisfaction, and uncorrected distance visual acuity. RESULTS: Most patients in both groups were in the age group of 51-70 years. Overall satisfaction was comparable in teleconsultation and hospital visit groups (3.74 ± 0.23 vs. 3.72 ± 0.27; P = 0.22). The majority of patients had visual acuity 6/18-6/6 on postoperative day 1, day 7, and day 30-40 in both groups. Lid edema, pain, redness, watering, and congestion complications were more in the hospital visit group on postoperative day 1. CONCLUSION: The study concludes that patients with no preexisting ocular and systemic comorbidity undergoing an uneventful phacoemulsification cataract surgery teleconsultation approach can be used for follow-up without any impact on the postoperative visual outcome and patient satisfaction, thereby increasing the efficiency and productivity of health-care system. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Effective refractive error coverage in adults aged 50 years and older: estimates from population-based surveys in 61 countries

Author

Bourne, Rupert Richard Alexander, primary, Cicinelli, Maria Vittoria, additional, Sedighi, Tabassom, additional, Tapply, Ian H, additional, McCormick, Ian, additional, Jonas, Jost B, additional, Congdon, Nathan G, additional, Ramke, Jacqueline, additional, Naidoo, Kovin S, additional, Fricke, Timothy R, additional, Burton, Matthew J, additional, Müller, Andreas, additional, Bikbov, Mukharram M, additional, Furtado, João M, additional, Kyari, Fatima, additional, He, Mingguang, additional, Wang, Ya Xing, additional, Vijaya, Lingam, additional, Nangia, Vinay, additional, Brian, Garry, additional, Emamian, Mohammad Hassan, additional, Fotouhi, Akbar, additional, Hashemi, Hassan, additional, Khandekar, Rajiv B, additional, Marmamula, Srinivas, additional, Salomão, Solange, additional, George, Ronnie, additional, Kazakbaeva, Gyulli, additional, Braithwaite, Tasanee, additional, Casson, Robert J, additional, Iwase, Aiko, additional, Gupta, Noopur, additional, Abdianwall, Mohammad H, additional, Varma, Rohit, additional, Wong, Tien Y, additional, Wang, Ningli, additional, Taylor, Hugh R, additional, Flaxman, Seth R, additional, Keel, Stuart, additional, Resnikoff, Serge, additional, Bron, Alain, additional, Cheng, Ching-Yu, additional, Fernandes, Arthur, additional, Friedman, David, additional, Gazzard, Andrew, additional, Kahloun, Rim, additional, Kempen, John, additional, Khairallah, Moncef, additional, Lansingh, Van C, additional, Leasher, Janet, additional, Leveziel, Nicolas, additional, Limburg, Hans, additional, Nowak, Michal, additional, Pesudovs, Konrad, additional, Peto, Tunde, additional, Rossetti, Luca, additional, Tahhan, Nina, additional, Alemayehu, Wondu, additional, Arditi, Aries, additional, Dana, Reza, additional, Del Monte, Monte, additional, Deva, jenny, additional, Dreer, Laura, additional, Ehrlich, Josh, additional, Ellwein, Leon, additional, Hammond, Billy, additional, Hartnett, Mary E, additional, Ingram, April, additional, Khanna, Rohit, additional, Kim, Judy, additional, Lim, Jennifer, additional, Morse, Alan, additional, Musch, David, additional, Parodi, Maurizio B, additional, Ramulu, Pradeep, additional, Robin, Alan, additional, Serle, Janet, additional, Shen, Tueng, additional, Sitorus, Rita S, additional, Stambolian, Dwight, additional, Topouzis, Fotis, additional, Tsilimbaris, Miltiadis, additional, Virgili, Gianni, additional, West, Sheila, additional, Ababora, Jafer K, additional, AlSawahli, Heba, additional, Andriamanjato, Hery Harimanitra, additional, Barrenechea, Rosario, additional, Batlle, Juan F, additional, Burnett, Anthea M, additional, Finger, Robert P, additional, Gallarreta, Marcelo, additional, Gomez-Bastar, Pedro A, additional, Gurung, Reeta, additional, Jain, Elesh, additional, Kabona, George E, additional, Kalua, Khumbo, additional, Kandeke, Levi, additional, Karimurio, Jefitha, additional, Kikira, Susan A, additional, Kulkarni, Sucheta, additional, Mathenge, Wanjiku, additional, Mishra, Sailesh Kumar, additional, Mohammadi, Seyed Farzad, additional, Mörchen, Manfred, additional, Muhammad, Nasiru, additional, Mutati, Grace C, additional, Nano, Maria Eugenia, additional, Németh, János, additional, Paduca, Ala, additional, Páez, Alexander, additional, Rabiu, M Mansur, additional, Rif'ati, Lutfah, additional, Salowi, Mohamad Aziz, additional, Sapkota, Yuddha D, additional, Sargent, Nicholas, additional, Thoufeeq, Ubeydulla, additional, Villalobos, Astrid V, additional, Xiao, Biaxiang, additional, Yee Melgar, Mariano, additional, and Zhang, Xiu Juan, additional

Published
2022
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35. Prevalence of diabetic retinopathy in India stratified by known and undiagnosed diabetes, urban–rural locations, and socioeconomic indices: results from the SMART India population-based cross-sectional screening study

Author

Raman, Rajiv, primary, Vasconcelos, Joana C, additional, Rajalakshmi, Ramachandran, additional, Prevost, A Toby, additional, Ramasamy, Kim, additional, Mohan, Viswanathan, additional, Mohan, Deepa, additional, Rani, Padmaja K, additional, Conroy, Dolores, additional, Das, Taraprasad, additional, Sivaprasad, Sobha, additional, Bhende, Pramod, additional, Surya, Janani, additional, Gopal, Lingam, additional, Ramakrishnan, Radha, additional, Roy, Rupak, additional, Das, Supita, additional, Manayath, George, additional, Pooleeswaran, Vignesh T, additional, Anantharaman, Giridhar, additional, Gopalakrishnan, Mahesh, additional, Natarajan, Sundaram, additional, Krishnan, Radhika, additional, Mani, Sheena Liz, additional, Agarwal, Manisha, additional, Behera, Umesh, additional, Bhattacharjee, Harsha, additional, Barman, Manabjyoti, additional, Sen, Alok, additional, Saxena, Moneesh, additional, Sil, Asim K, additional, Chakrabarty, Subhratanu, additional, Cherian, Thomas, additional, Jitesh, Reesha, additional, Naigaonkar, Rushikesh, additional, Desai, Abishek, additional, and Kulkarni, Sucheta, additional

Published
2022
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36. Effective cataract surgical coverage in adults aged 50 years and older: estimates from population-based surveys in 55 countries

Author

McCormick, Ian, primary, Butcher, Robert, additional, Evans, Jennifer R, additional, Mactaggart, Islay Z, additional, Limburg, Hans, additional, Jolley, Emma, additional, Sapkota, Yuddha D, additional, Oye, Joseph Enyegue, additional, Mishra, Sailesh Kumar, additional, Bastawrous, Andrew, additional, Furtado, João M, additional, Joshi, Anagha, additional, Xiao, Baixiang, additional, Ravilla, Thulasiraj D, additional, Bourne, Rupert R A, additional, Cieza, Alarcos, additional, Keel, Stuart, additional, Burton, Matthew J, additional, Ramke, Jacqueline, additional, Ababora, Jafer K, additional, AlSawahli, Heba, additional, Alvarado, Doris M, additional, Andriamanjato, Hery Harimanitra, additional, Ashraf Amalius, Ahmad, additional, Barrenechea, Rosario, additional, Batlle, Juan F, additional, Brea, Ileana, additional, Burnett, Anthea M, additional, Chiriboga, Felipe A, additional, Davaatseren, Uranchimeg, additional, Duerksen, Rainald, additional, Eusebio, Cristina I, additional, Finger, Robert P, additional, Gomez-Bastar, Pedro A, additional, Gonzales, César, additional, Gurung, Reeta, additional, Hajar, Saad, additional, Jadoon, Muhammad Zahid, additional, Jain, Elesh, additional, Kabona, George E, additional, Kalua, Khumbo, additional, Kandeke, Levi, additional, Kandel, Ram P, additional, Karimurio, Jefitha, additional, Kulkarni, Sucheta, additional, Lansingh, Van C, additional, Lepcha, Nor T, additional, Mathenge, Wanjiku, additional, Mohammadi, Seyed Farzad, additional, Mörchen, Manfred, additional, Muhammad, Nasiru, additional, Musana, Paddy B, additional, Mutati, Grace C, additional, Nano, Maria Eugenia, additional, Németh, János, additional, Paduca, Ala, additional, Páez, Alexander, additional, Polack, Sarah, additional, Rabiu, M Mansur, additional, Rif'ati, Lutfah, additional, Rodríguez Rodríguez, Beatriz Natividad, additional, Salowi, Mohamad Aziz, additional, Sargent, Nicholas, additional, Syumarti, Mansyur, additional, Thoufeeq, Ubeydulla, additional, Villalobos, Astrid V, additional, Wachira, Joseph W, additional, Wu, Min, additional, Xiao, Biaxiang, additional, Yee Melgar, Mariano, additional, and Zhang, Xiu Juan, additional

Published
2022
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38. Impact of treatment of diabetic macular edema on visual impairment in people with diabetes mellitus in India

Author

Kulkarni, Sucheta, Ramachandran, Rajalakshmi, Sivaprasad, Sobha, Rani, Padmaja, Behera, Umesh, Vignesh, T., Chawla, Gajendra, Agarwal, Manisha, Mani, Sheena, Ramasamy, Kim, and Raman, Rajiv

Subjects
Diabetic retinopathy -- Complications and side effects -- Care and treatment, Eye diseases -- Complications and side effects -- Care and treatment, Vision disorders -- Development and progression -- Care and treatment, Health
Abstract

Byline: Sucheta. Kulkarni, Rajalakshmi. Ramachandran, Sobha. Sivaprasad, Padmaja. Rani, Umesh. Behera, T. Vignesh, Gajendra. Chawla, Manisha. Agarwal, Sheena. Mani, Kim. Ramasamy, Rajiv. Raman Purpose: The aim of this study was [...]

Published
2021

39. Role of anoctamins in cancer and apoptosis

Author

Wanitchakool, Podchanart, Wolf, Luisa, Koehl, Gudrun E., Sirianant, Lalida, Schreiber, Rainer, Kulkarni, Sucheta, Duvvuri, Umamaheswar, and Kunzelmann, Karl

Published
2014

43. Retinopathy of prematurity: Maharashtra state model

Author

Kulkarni, Sucheta, Kadam, Sandeep, Patil, Archana, and Gilbert, Clare

Subjects
Queen Elizabeth II's Diamond Jubilee, 2012, Hospitals -- India, Public health, Neonatology, Ophthalmology, Infant care, Retinopathy of prematurity, Public-private sector cooperation, Newborn infants, Pediatrics, Public health movements, Infrastructure (Economics), Health
Abstract

Byline: Sucheta. Kulkarni, Sandeep. Kadam, Archana. Patil, Clare. Gilbert This report describes the goal, activities, and outcomes of the Queen Elizabeth Diamond Jubilee Trust funded retinopathy of prematurity (ROP) program [...]

Published
2020

44. A Novel Method to Improve Inter-Clinician Variation in the Diagnosis of Retinopathy of Prematurity Using Machine Learning.

Author

Nisha, K. L., Ganapathy, Sreelekha, Puthumangalathu Savithri, Sathidevi, Idaguri, Madhu, Mohanachandran, Poornima, Vinekar, Anand, Chandra, Parijat, Kulkarni, Sucheta, and Dogra, Mangat

Subjects
RETROLENTAL fibroplasia, MACHINE learning, PREMATURE infants, USER interfaces, DISEASE management
Abstract

Inter-clinician variation could cause uncertainty in disease management. This is reported to be high in Retinopathy of Prematurity (ROP), a potentially blinding retinal disease affecting premature infants. Machine learning has the potential to quantify the differences in decision-making between ROP specialists and trainees and may improve the accuracy of diagnosis. An anonymized survey of ROP images was administered to the expert(s) and the trainee(s) using a study-designed user interface. The results were analyzed for repeatability as well as to identify the level of agreement in the classification. "Ground truth" was prepared for each individual and a unique classifier was built for each individual using the same. The classifier allowed the identification of the most important features used by each individual. Correlation and disagreement between the expert and the trainees were visualized using the Dipstick™ diagram. Intra-clinician repeatability and reclassification statistics were assessed for all. The repeatability was 88.4% and 86.2% for two trainees and 92.1% for the expert, respectively. Commonly used features differed for the expert and the trainees and accounted for the variability. This novel, automated algorithm quantifies the differences using machine learning techniques. This will help audit the training process by objectively measuring differences between experts and trainees. Training for image-based ROP diagnosis can be more objectively performed using this novel, machine learning-based automated image analyzer and classifier. [ABSTRACT FROM AUTHOR]

Published
2023
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46. Correction: Genetic Dissociation of Glycolysis and the TCA Cycle Affects Neither Normal nor Neoplastic Proliferation

Author

Jackson, Laura E., primary, Kulkarni, Sucheta, additional, Wang, Huabo, additional, Lu, Jie, additional, Dolezal, James M., additional, Bharathi, Sivakama S., additional, Ranganathan, Sarangarajan, additional, Patel, Mulchand S., additional, Deshpande, Rahul, additional, Alencastro, Frances, additional, Wendell, Stacy G., additional, Goetzman, Eric S., additional, Duncan, Andrew W., additional, and Prochownik, Edward V., additional

Published
2022
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47. Fungal Endophthalmitis

Author

Das, Taraprasad, primary, Agarwal, Manisha, additional, Anand, Appakkudal R., additional, Behera, Umesh C., additional, Bhende, Muna, additional, Das, Anthony Vipin, additional, Dasgupta, Debarati, additional, Dave, Vivek P., additional, Gandhi, Jaishree, additional, Gunasekaran, Rameshkumar, additional, Joseph, Joveeta, additional, Kulkarni, Sucheta, additional, Lalitha, Prajna, additional, Mahendrakar, Priyanka A., additional, Mitra, Sanchita, additional, Mohamed, Ashik, additional, Muralidhar, Alankrita, additional, Nimeshika, Pillutla L., additional, Prashanthi MTech, Gumpalli S., additional, Sen, Alok, additional, Sharma, Savitri, additional, and Uday, Prithviraj, additional

Published
2022
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49. Grand Challenges in global eye health: a global prioritisation process using Delphi method

Author

Ramke, Jacqueline, primary, Evans, Jennifer R, additional, Habtamu, Esmael, additional, Mwangi, Nyawira, additional, Silva, Juan Carlos, additional, Swenor, Bonnielin K, additional, Congdon, Nathan, additional, Faal, Hannah B, additional, Foster, Allen, additional, Friedman, David S, additional, Gichuhi, Stephen, additional, Jonas, Jost B, additional, Khaw, Peng T, additional, Kyari, Fatima, additional, Murthy, Gudlavalleti V S, additional, Wang, Ningli, additional, Wong, Tien Y, additional, Wormald, Richard, additional, Yusufu, Mayinuer, additional, Taylor, Hugh, additional, Resnikoff, Serge, additional, West, Sheila K, additional, Burton, Matthew J, additional, Aghaji, Ada, additional, Adewole, Adeyemi T, additional, Csutak, Adrienne, additional, Salam, Ahmad Shah, additional, Paduca, Ala, additional, Bron, Alain M, additional, Denniston, Alastair K, additional, Lazo Legua, Alberto, additional, Halim, Aldiana, additional, Tefera, Alemayehu Woldeyes, additional, Mwangi, Alice, additional, Jenkins, Alicia J, additional, Davis, Amanda, additional, Meddeb-Ouertani, Amel, additional, Wali, Amina H, additional, Palis, Ana G, additional, Bastos de Carvalho, Ana, additional, Joshi, Anagha, additional, Kreis, Andreas J, additional, Mueller, Andreas, additional, Bastawrous, Andrew, additional, Cooper, Andrew, additional, Smith, Andrew F, additional, Grzybowski, Andrzej, additional, Arvind, Anitha, additional, Karanu, Anne M, additional, Orlina, Anne O, additional, Burnett, Anthea, additional, Yashadhana, Aryati, additional, Abeydeera, Asela P, additional, Abdurakhmanova, Aselia, additional, Mohamed, Ashik, additional, Bacchav, Ashish, additional, Bernhisel, Ashlie, additional, Webson, Aubrey Walton, additional, Azuara-Blanco, Augusto, additional, Hossain, Ava, additional, Ilhan, Bayazit, additional, Assumpta Lucienne, Bella, additional, Tousignant, Benoit, additional, Shamanna, Bindiganavale R, additional, Wiafe, Boateng, additional, Mueller, Brigitte, additional, Caglar, Cagatay, additional, Mpyet, Caleb, additional, Abraham, Carl H, additional, Cheung, Carol Y, additional, Thiel, Cassandra L, additional, Jan, Catherine L, additional, Emedike, Chike, additional, Chuluunkhuu, Chimgee, additional, Chinyere, Chinomso, additional, Henein, Christin, additional, Gilbert, Clare E, additional, Bascaran, Covadonga, additional, Nitulescu, Cristina Elena, additional, Patel, Daksha, additional, Bachani, Damodar, additional, Kiage, Daniel, additional, Etya'ale, Daniel, additional, Dahdal, David, additional, Woo Lawson, Dawn, additional, Godin, Denise, additional, Nkanga, Dennis G, additional, Ondeyo, Dennis M, additional, O'Brien, Donna, additional, Mutie, Dorothy M, additional, Alalawi, Ebtisam S K, additional, Mayorga, Eduardo, additional, Bin Hashim, Effendy, additional, Ashrafi, Elham, additional, Kishiki, Elizabeth Andrew, additional, Kurian, Elizabeth, additional, D'Esposito, Fabrizio, additional, Masila, Faith, additional, Pena, Fernando Yaacov, additional, Büsch, Fortunat, additional, Topouzis, Fotis, additional, Bandello, Francesco, additional, Oyediji, Funmilayo J, additional, Thumann, Gabriele, additional, Ezz Elarab, Gamal, additional, Kitema, Gatera Fiston, additional, Schlenther, Gerhard, additional, Fefoame, Gertrude Oforiwa, additional, Cochrane, Gillian M, additional, Laganovska, Guna, additional, Awan, Haroon R, additional, Ansari, Harris M, additional, Philippin, Heiko, additional, Burn, Helen, additional, Dimaras, Helen, additional, Filipe, Helena P, additional, Monye, Henrietta I, additional, Kandel, Himal, additional, Randrianarisoa, Hoby Lalaina, additional, Jones, Iain, additional, Murdoch, Ian E, additional, Fabian, Ido Didi, additional, Khan, Imran A, additional, Sharma, Indra P, additional, Elbeih, Islam, additional, Mactaggart, Islay, additional, Pastor, J Carlos, additional, Keunen, Jan E E, additional, Ohuma, Jane A, additional, Pithuwa Nirwoth, Jason, additional, Hammou, Jaouad, additional, Vianna, Jayme R, additional, Biao, Jean-eudes, additional, Burr, Jennifer M, additional, Keenan, Jeremy D, additional, Blijkers, Jess, additional, Black, Joanna M, additional, Barbosa Breda, Joao, additional, Furtado, Joao M, additional, Buchan, John C, additional, Lawrenson, John G, additional, Kempen, John H, additional, Ehrlich, Joshua R, additional, Stern, Judith, additional, Zhang, Justine H, additional, Keskinbora, Kadircan H, additional, Knoll, Karin M, additional, Blanchet, Karl, additional, Schmid, Katrina L, additional, Ono, Koichi, additional, Ogundimu, Kolawole, additional, Balo, Komi, additional, Somda, Kussome Paulin, additional, Yeboah, Kwame, additional, Amissah-Arthur, Kwesi N, additional, Nasehi, Leone, additional, Øverland, Lene, additional, Vijaya, Lingam, additional, Keay, Lisa, additional, Hamm, Lisa M, additional, Mowatt, Lizette, additional, Harrison-Williams, Lloyd C M, additional, Silva, Lucia, additional, Bilotto, Luigi, additional, Mörchen, Manfred, additional, Rabiu, Mansur, additional, Zondervan, Marcia, additional, Chagunda, Margarida, additional, Sandinha, Maria Teresa, additional, Yee Melgar, Mariano, additional, Salas Vargas, Marisela, additional, Daniell, Mark D, additional, Katibeh, Marzieh, additional, Broom, Matt, additional, Collins, Megan E, additional, Alp, Mehmet Numan, additional, Kwarteng, Michael A, additional, Belkin, Michael, additional, Gichangi, Michael, additional, Sylvanowicz, Michelle, additional, Wu, Min, additional, Cano, Miriam R, additional, Shalaby, Mohammad, additional, Duggal, Mona, additional, Khairallah, Moncef, additional, Batur, Muhammed, additional, Bikbov, Mukharram M, additional, Ramappa, Muralidhar, additional, Pamarathi, Nagaraju, additional, Khachatryan, Naira, additional, Muhammad, Nasiru, additional, Kennedy, Neil, additional, Murray, Neil, additional, Beare, Nicholas A V, additional, Astbury, Nick, additional, Carnt, Nicole A, additional, St Rose, Nigel A, additional, Barker, Nigel H, additional, Pehere, Niranjan K, additional, Uche, Nkechinyere J, additional, Lois, Noemi, additional, Awe, Oluwaseun O, additional, Mujica, Oscar J, additional, Okolo, Oteri E, additional, Rani, Padmaja Kumari, additional, Ruamviboonsuk, Paisan, additional, Ndiaye, Papa Amadou, additional, Dhakhwa, Parami, additional, Rozsival, Pavel, additional, Mbulawa, Pearl K, additional, Keane, Pearse A, additional, Jones, Pete R, additional, Holland, Peter, additional, Nukella, Phanindra Babu, additional, Burgess, Philip I, additional, O'Dwyer, Pinar Aydin, additional, Piyasena, Prabhath, additional, Bastola, Pradeep, additional, Morjaria, Priya, additional, Nasimee, Qais, additional, Rambacal, Raizza A T, additional, Das, Rajdeep, additional, Khandekar, Rajiv B, additional, Azad, Rajvardhan, additional, Bashshur, Ramona, additional, Sousa, Raúl A R C, additional, Oenga, Rebecca, additional, Gurung, Reeta, additional, Geneau, Robert, additional, Jacobs, Robert J, additional, Finger, Robert P, additional, Guymer, Robyn H, additional, Sevciuc, Rodica, additional, Khanna, Rohit C, additional, George, Ronnie, additional, Graham, Ronnie, additional, Kawasaki, Ryo, additional, Ho, S May, additional, Mishra, Sailesh Kumar, additional, Buttan, Sandeep, additional, Block, Sandra S, additional, Talero, Sandra, additional, Yoon, Sangchul, additional, Joseph, Sanil, additional, Safi, Sare, additional, Dodson, Sarity, additional, Munoz, Sergio R, additional, Bakayoko, Seydou, additional, Mohammadi, Seyed Farzad, additional, Muez, Shabir Ahmad, additional, Pardhan, Shahina, additional, Hopkins, Shelley, additional, Sheu, Shwu-Jiuan, additional, Coulibaly, Sidi Mohamed, additional, Schellini, Silvana A, additional, Arunga, Simon, additional, Bush, Simon R, additional, Sivaprasad, Sobha, additional, Salomao, Solange R, additional, Marmamula, Srinivas, additional, Onwubiko, Stella N, additional, Misra, Stuti L, additional, Kuyyadiyil, Subeesh, additional, Kulkarni, Sucheta, additional, khanal, Sudarshan, additional, Yasmin, Sumrana, additional, Pavljasevic, Suzana Nikolic, additional, Gilbert, Suzanne S, additional, Braithwaite, Tasanee, additional, Ghidirimschi, Tatiana, additional, Ravilla, Thulasiraj, additional, Fricke, Timothy R, additional, Cogliati, Tiziana, additional, Kassa, Tsehaynesh, additional, Peto, Tunde, additional, Dibb, Ute, additional, Lansingh, Van C, additional, Hu, Victor H, additional, Sheffield, Victoria M, additional, Mathenge, Wanjiku, additional, Dean, William H, additional, Nolan, Winifred, additional, Hiratsuka, Yoshimune, additional, Mahsood, Yousaf Jamal, additional, and Sapkota, Yuddha, additional

Published
2022
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