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652 results on '"Kulka, Janina"'

1. TRPS1 expression in breast angiosarcoma

Author

Pancsa, Tamás, Pósfai, Boglárka, Schubert, Anna, Almási, Szintia, Papp, Eszter, Chien, Yi-Che Chang, Kálmán, Endre, Kovács, Kristóf Attila, Kulka, Janina, Varga, Linda, Cserni, Gábor, and Kuthi, Levente

Published
2024
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3. Revisiting surgical margins for invasive breast cancer patients treated with breast conservation therapy - Evidence for adopting a 1 mm negative width

Author

Rakha, Emad A., Quinn, Cecily, Masannat, Yazan A., Lee, Andrew H. S., Tan, Puay Hoon, Karakatsanis, Andreas, Matrai, Zoltan Tamas, Al Shaibani, Salman Husain M., Gehani, Salahddin A., Shaaban, Abeer, Khout, Hazem, Chagla, Leena, Cserni, Gábor, Varga, Zsuzsanna, Yong, Wong Fuh, Meattini, Icro, Kulka, Janina, Yang, Wentao, Tse, Gary M., Pinder, Sarah E., Fox, Stephen, and Dixon, J Michael

Published
2024
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4. Histopathological growth patterns and tumor-infiltrating lymphocytes in breast cancer liver metastases

Author

Leduc, Sophia, De Schepper, Maxim, Richard, François, Maetens, Marion, Pabba, Anirudh, Borremans, Kristien, Jaekers, Joris, Latacz, Emily, Zels, Gitte, Bohlok, Ali, Van Baelen, Karen, Nguyen, Ha Linh, Geukens, Tatjana, Dirix, Luc, Larsimont, Denis, Vankerckhove, Sophie, Santos, Eva, Oliveira, Rui Caetano, Dede, Kristòf, Kulka, Janina, Borbala, Székely, Salamon, Ferenc, Madaras, Lilla, Marcell Szasz, A., Lucidi, Valerio, Meyer, Yannick, Topal, Baki, Verhoef, Cornelis, Engstrand, Jennie, Moro, Carlos Fernandez, Gerling, Marco, Bachir, Imane, Biganzoli, Elia, Donckier, Vincent, Floris, Giuseppe, Vermeulen, Peter, and Desmedt, Christine

Published
2023
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5. Third International Consensus Conference on lesions of uncertain malignant potential in the breast (B3 lesions)

Author

Elfgen, Constanze, Leo, Cornelia, Kubik-Huch, Rahel A., Muenst, Simone, Schmidt, Noemi, Quinn, Cecily, McNally, Sorcha, van Diest, Paul J., Mann, Ritse M, Bago-Horvath, Zsuzsanna, Bernathova, Maria, Regitnig, Peter, Fuchsjäger, Michael, Schwegler-Guggemos, Daniela, Maranta, Martina, Zehbe, Sabine, Tausch, Christoph, Güth, Uwe, Fallenberg, Eva Maria, Schrading, Simone, Kothari, Ashutosh, Sonnenschein, Martin, Kampmann, Gert, Kulka, Janina, Tille, Jean-Christophe, Körner, Meike, Decker, Thomas, Lax, Sigurd F., Daniaux, Martin, Bjelic-Radisic, Vesna, Kacerovsky-Strobl, Stephanie, Condorelli, Rosaria, Gnant, Michael, and Varga, Zsuzsanna

Published
2023
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7. Results of a worldwide survey on the currently used histopathological diagnostic criteria for invasive lobular breast cancer

Author

De Schepper, Maxim, Vincent-Salomon, Anne, Christgen, Matthias, Van Baelen, Karen, Richard, François, Tsuda, Hitoshi, Kurozumi, Sasagu, Brito, Maria Jose, Cserni, Gabor, Schnitt, Stuart, Larsimont, Denis, Kulka, Janina, Fernandez, Pedro Luis, Rodríguez-Martínez, Paula, Olivar, Ana Aula, Melendez, Cristina, Van Bockstal, Mieke, Kovacs, Aniko, Varga, Zsuzsanna, Wesseling, Jelle, Bhargava, Rohit, Boström, Pia, Franchet, Camille, Zambuko, Blessing, Matute, Gustavo, Mueller, Sophie, Berghian, Anca, Rakha, Emad, van Diest, Paul J., Oesterreich, Steffi, Derksen, Patrick W. B., Floris, Giuseppe, and Desmedt, Christine

Published
2022
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8. Dataset for reporting of the invasive carcinoma of the breast: recommendations from the International Collaboration on Cancer Reporting (ICCR)

Author

Ellis, Ian, primary, Webster, Fleur, additional, Allison, Kimberly H, additional, Dang, Chau, additional, Gobbi, Helenice, additional, Kulka, Janina, additional, Lakhani, Sunil R, additional, Moriya, Takuya, additional, Quinn, Cecily M, additional, Sapino, Anna, additional, Schnitt, Stuart, additional, Sibbering, D Mark, additional, Slodkowska, Elzbieta, additional, Yang, Wentao, additional, and Tan, Puay H, additional

Published
2024
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11. Radial Scar

Author

Kulka, Janina, van Krieken, J. H. J. M., Series Editor, Sapino, Anna, editor, and Kulka, Janina, editor

Published
2020
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15. Digital Whole Slide Image Analysis of Elevated Stromal Content and Extracellular Matrix Protein Expression Predicts Adverse Prognosis in Triple-Negative Breast Cancer.

Author

Karancsi, Zsófia, Gregus, Barbara, Krenács, Tibor, Cserni, Gábor, Nagy, Ágnes, Szőcs-Trinfa, Klementina Fruzsina, Kulka, Janina, and Tőkés, Anna Mária

Subjects
TRIPLE-negative breast cancer, EXTRACELLULAR matrix proteins, BREAST cancer prognosis, OVERALL survival, PROGNOSIS
Abstract

Triple-negative breast cancer (TNBC) is a subtype of breast cancer with a poor prognosis and limited treatment options. This study evaluates the prognostic value of stromal markers in TNBC, focusing on the tumor–stroma ratio (TSR) and overall stroma ratio (OSR) in whole slide images (WSI), as well as the expression of type-I collagen, type-III collagen, and fibrillin-1 on tissue microarrays (TMAs), using both visual assessment and digital image analysis (DIA). A total of 101 female TNBC patients, primarily treated with surgery between 2005 and 2016, were included. We found that high visual OSR correlates with worse overall survival (OS), advanced pN categories, lower stromal tumor-infiltrating lymphocyte count (sTIL), lower mitotic index, and patient age (p < 0.05). TSR showed significant connections to the pN category and mitotic index (p < 0.01). High expression levels of type-I collagen (>45%), type-III collagen (>30%), and fibrillin-1 (>20%) were linked to significantly worse OS (p = 0.004, p = 0.013, and p = 0.005, respectively) and progression-free survival (PFS) (p = 0.028, p = 0.025, and p = 0.002, respectively), validated at the mRNA level. Our results highlight the importance of stromal characteristics in promoting tumor progression and metastasis and that targeting extracellular matrix (ECM) components may offer novel therapeutic strategies. Furthermore, DIA can be more accurate and objective in evaluating TSR, OSR, and immunodetected stromal markers than traditional visual examination. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Research autopsy programmes in oncology: shared experience from 14 centres across the world

Author

Geukens, Tatjana, primary, Maetens, Marion, additional, Hooper, Jody E, additional, Oesterreich, Steffi, additional, Lee, Adrian V, additional, Miller, Lori, additional, Atkinson, Jenny M, additional, Rosenzweig, Margaret, additional, Puhalla, Shannon, additional, Thorne, Heather, additional, Devereux, Lisa, additional, Bowtell, David, additional, Loi, Sherene, additional, Bacon, Eliza R, additional, Ihle, Kena, additional, Song, Mihae, additional, Rodriguez‐Rodriguez, Lorna, additional, Welm, Alana L, additional, Gauchay, Lisa, additional, Murali, Rajmohan, additional, Chanda, Pharto, additional, Karacay, Ali, additional, Naceur‐Lombardelli, Cristina, additional, Bridger, Hayley, additional, Swanton, Charles, additional, Jamal‐Hanjani, Mariam, additional, Kollath, Lori, additional, True, Lawrence, additional, Morrissey, Colm, additional, Chambers, Meagan, additional, Chinnaiyan, Arul M, additional, Wilson, Allecia, additional, Mehra, Rohit, additional, Reichert, Zachery, additional, Carey, Lisa A, additional, Perou, Charles M, additional, Kelly, Erin, additional, Maeda, Daichi, additional, Goto, Akiteru, additional, Kulka, Janina, additional, Székely, Borbála, additional, Szasz, A Marcell, additional, Tőkés, Anna‐Mária, additional, Van Den Bogaert, Wouter, additional, Floris, Giuseppe, additional, and Desmedt, Christine, additional

Published
2024
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19. A dedicated structured data set for reporting of invasive carcinoma of the breast in the setting of neoadjuvant therapy: recommendations from the International Collaboration on Cancer Reporting (ICCR)

Author

Bossuyt, Veerle, primary, Provenzano, Elena, additional, Symmans, W Fraser, additional, Webster, Fleur, additional, Allison, Kimberly H, additional, Dang, Chau, additional, Helenice, Gobbi, additional, Kulka, Janina, additional, Lakhani, Sunil R, additional, Moriya, Takuya, additional, Quinn, Cecily M, additional, Sapino, Anna, additional, Schnitt, Stuart, additional, Sibbering, D Mark, additional, Slodkowska, Elzbieta, additional, Yang, Wentao, additional, Tan, Puay Hoon, additional, and Ellis, Ian, additional

Published
2024
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28. The Prediction Analysis of Microarray 50 (PAM50) Gene Expression Classifier Utilized in Indeterminate-Risk Breast Cancer Patients in Hungary: A Consecutive 5-Year Experience

Author

Dank, Magdolna, primary, Mühl, Dorottya, additional, Pölhös, Annamária, additional, Csanda, Renata, additional, Herold, Magdolna, additional, Kovacs, Attila Kristof, additional, Madaras, Lilla, additional, Kulka, Janina, additional, Palhazy, Timea, additional, Tokes, Anna-Maria, additional, Toth, Monika, additional, Ujhelyi, Mihaly, additional, Szasz, Attila Marcell, additional, and Herold, Zoltan, additional

Published
2023
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30. Data from Heterogeneity of Circulating Tumor Cell–Associated Genomic Gains in Breast Cancer and Its Association with the Host Immune Response

Author

Kanwar, Nisha, primary, Balde, Zaldy, primary, Nair, Ranju, primary, Dawe, Melanie, primary, Chen, Shiyi, primary, Maganti, Manjula, primary, Atenafu, Eshetu G., primary, Manolescu, Sabrina, primary, Wei, Carrie, primary, Mao, Amanda, primary, Fu, Fred, primary, Wang, Dan, primary, Cheung, Alison, primary, Yerofeyeva, Yulia, primary, Peters, Rachel, primary, Liu, Kela, primary, Desmedt, Christine, primary, Sotiriou, Christos, primary, Szekely, Borbala, primary, Kulka, Janina, primary, McKee, Trevor D., primary, Hirano, Naoto, primary, Bartlett, John M.S., primary, Yaffe, Martin J., primary, Bedard, Philippe L., primary, McCready, David, primary, and Done, Susan J., primary

Published
2023
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31. Supplementary File from Heterogeneity of Circulating Tumor Cell–Associated Genomic Gains in Breast Cancer and Its Association with the Host Immune Response

Author

Kanwar, Nisha, primary, Balde, Zaldy, primary, Nair, Ranju, primary, Dawe, Melanie, primary, Chen, Shiyi, primary, Maganti, Manjula, primary, Atenafu, Eshetu G., primary, Manolescu, Sabrina, primary, Wei, Carrie, primary, Mao, Amanda, primary, Fu, Fred, primary, Wang, Dan, primary, Cheung, Alison, primary, Yerofeyeva, Yulia, primary, Peters, Rachel, primary, Liu, Kela, primary, Desmedt, Christine, primary, Sotiriou, Christos, primary, Szekely, Borbala, primary, Kulka, Janina, primary, McKee, Trevor D., primary, Hirano, Naoto, primary, Bartlett, John M.S., primary, Yaffe, Martin J., primary, Bedard, Philippe L., primary, McCready, David, primary, and Done, Susan J., primary

Published
2023
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32. Supplementary Information from Heterogeneity of Circulating Tumor Cell–Associated Genomic Gains in Breast Cancer and Its Association with the Host Immune Response

Author

Kanwar, Nisha, primary, Balde, Zaldy, primary, Nair, Ranju, primary, Dawe, Melanie, primary, Chen, Shiyi, primary, Maganti, Manjula, primary, Atenafu, Eshetu G., primary, Manolescu, Sabrina, primary, Wei, Carrie, primary, Mao, Amanda, primary, Fu, Fred, primary, Wang, Dan, primary, Cheung, Alison, primary, Yerofeyeva, Yulia, primary, Peters, Rachel, primary, Liu, Kela, primary, Desmedt, Christine, primary, Sotiriou, Christos, primary, Szekely, Borbala, primary, Kulka, Janina, primary, McKee, Trevor D., primary, Hirano, Naoto, primary, Bartlett, John M.S., primary, Yaffe, Martin J., primary, Bedard, Philippe L., primary, McCready, David, primary, and Done, Susan J., primary

Published
2023
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33. Genomic Landscape of Normal and Breast Cancer Tissues in a Hungarian Pilot Cohort

Author

Pipek, Orsolya, primary, Alpár, Donát, additional, Rusz, Orsolya, additional, Bödör, Csaba, additional, Udvarnoki, Zoltán, additional, Medgyes-Horváth, Anna, additional, Csabai, István, additional, Szállási, Zoltán, additional, Madaras, Lilla, additional, Kahán, Zsuzsanna, additional, Cserni, Gábor, additional, Kővári, Bence, additional, Kulka, Janina, additional, and Tőkés, Anna Mária, additional

Published
2023
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44. Experimental workflow from A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer

Author

Humphries, Matthew P., primary, Sundara Rajan, Sreekumar, primary, Droop, Alastair, primary, Suleman, Charlotte A.B., primary, Carbone, Carmine, primary, Nilsson, Cecilia, primary, Honarpisheh, Hedieh, primary, Cserni, Gabor, primary, Dent, Jo, primary, Fulford, Laura, primary, Jordan, Lee B., primary, Jones, J. Louise, primary, Kanthan, Rani, primary, Litwiniuk, Maria, primary, Di Benedetto, Anna, primary, Mottolese, Marcella, primary, Provenzano, Elena, primary, Shousha, Sami, primary, Stephens, Mark, primary, Walker, Rosemary A., primary, Kulka, Janina, primary, Ellis, Ian O., primary, Jeffery, Margaret, primary, Thygesen, Helene H., primary, Cappelletti, Vera, primary, Daidone, Maria G., primary, Hedenfalk, Ingrid A., primary, Fjällskog, Marie-Louise, primary, Melisi, Davide, primary, Stead, Lucy F., primary, Shaaban, Abeer M., primary, and Speirs, Valerie, primary

Published
2023
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46. Cut-off determination and representative staining profiles for eIF proteins determined by immunohistochemistry from A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer

Author

Humphries, Matthew P., primary, Sundara Rajan, Sreekumar, primary, Droop, Alastair, primary, Suleman, Charlotte A.B., primary, Carbone, Carmine, primary, Nilsson, Cecilia, primary, Honarpisheh, Hedieh, primary, Cserni, Gabor, primary, Dent, Jo, primary, Fulford, Laura, primary, Jordan, Lee B., primary, Jones, J. Louise, primary, Kanthan, Rani, primary, Litwiniuk, Maria, primary, Di Benedetto, Anna, primary, Mottolese, Marcella, primary, Provenzano, Elena, primary, Shousha, Sami, primary, Stephens, Mark, primary, Walker, Rosemary A., primary, Kulka, Janina, primary, Ellis, Ian O., primary, Jeffery, Margaret, primary, Thygesen, Helene H., primary, Cappelletti, Vera, primary, Daidone, Maria G., primary, Hedenfalk, Ingrid A., primary, Fjällskog, Marie-Louise, primary, Melisi, Davide, primary, Stead, Lucy F., primary, Shaaban, Abeer M., primary, and Speirs, Valerie, primary

Published
2023
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48. Interrogation of Oncomine{trade mark, serif} from A Case-Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic Markers in Male Breast Cancer

Author

Humphries, Matthew P., primary, Sundara Rajan, Sreekumar, primary, Droop, Alastair, primary, Suleman, Charlotte A.B., primary, Carbone, Carmine, primary, Nilsson, Cecilia, primary, Honarpisheh, Hedieh, primary, Cserni, Gabor, primary, Dent, Jo, primary, Fulford, Laura, primary, Jordan, Lee B., primary, Jones, J. Louise, primary, Kanthan, Rani, primary, Litwiniuk, Maria, primary, Di Benedetto, Anna, primary, Mottolese, Marcella, primary, Provenzano, Elena, primary, Shousha, Sami, primary, Stephens, Mark, primary, Walker, Rosemary A., primary, Kulka, Janina, primary, Ellis, Ian O., primary, Jeffery, Margaret, primary, Thygesen, Helene H., primary, Cappelletti, Vera, primary, Daidone, Maria G., primary, Hedenfalk, Ingrid A., primary, Fjällskog, Marie-Louise, primary, Melisi, Davide, primary, Stead, Lucy F., primary, Shaaban, Abeer M., primary, and Speirs, Valerie, primary

Published
2023
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50. Abstract P6-14-06: Histopathological and immune characterization of liver metastases from patients with breast cancer

Author

Leduc, Sophia, primary, De Schepper, Maxim, additional, Vermeulen, Peter, additional, Floris, Giuseppe, additional, Biganzoli, Elia, additional, Donckier, Vincent, additional, Bohlok, Ali, additional, Gerling, Marco, additional, Richard, François, additional, Maetens, Marion, additional, Jaekers, Joris, additional, Topal, Baki, additional, Latacz, Emily, additional, Van Baelen, Karen, additional, Geukens, Tatjana, additional, Nguyen, Ha Linh, additional, Dirix, Luc, additional, Larsimont, Denis, additional, Van Kerckhove, Sophie, additional, Oliveira, Rui Caetano, additional, Kulka, Janina, additional, Lucidi, Valerio, additional, Meyer, Yannick, additional, Verhoef, Cornelis, additional, Santos, Eva, additional, Salamon, Ferenc, additional, Madaras, Lilla, additional, Szasz, A. Marcell, additional, Borbála, Székely, additional, Dede, Kristòf, additional, Engstrand, Jennie, additional, Moro, Carlos Fernandez, additional, and Desmedt, Christine, additional

Published
2023
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