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103 results on '"Kulach A"'

1. 72 hour Holter monitoring, 7 day Holter monitoring, and 30 day intermittent patient-activated heart rhythm recording in detecting arrhythmias in cryptogenic stroke patients free from arrhythmia in a screening 24 h Holter

Author

Kułach Andrzej, Dewerenda Milena, Majewski Michał, Lasek-Bal Anetta, and Gąsior Zbigniew

Subjects
atrial fibrillation, cryptogenic ischemic stroke, holter ecg, patient-activated ecg recorder, supraventricular arrhythmia, svt runs, Medicine
Abstract

According to recent studies, silent atrial fibrillation (AF) is a common cause of cryptogenic ischemic stroke (CIS). 12-lead electrocardiogram (ECG) and 24 h Holter are not efficient to reveal an occult arrhythmic cause of stroke.

Published
2020
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2. Managed Care after Acute Myocardial Infarction (MC-AMI) – a Poland’s nationwide program of comprehensive post-MI care - improves prognosis in 12-month follow-up. Preliminary experience from a single high-volume center

Author

Wita, Krystian, Wilkosz, Katarzyna, Wita, Marcin, Kułach, Andrzej, Wybraniec, Maciej T., Polak, Mateusz, Matla, Monika, Maciejewski, Łukasz, Fluder, Joanna, Kalańska-Łukasik, Barbara, Skowerski, Tomasz, Gomułka, Szymon, Turski, Maciej, and Szydło, Krzysztof

Published
2019
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4. USE OF BIO-PRESERVATIVES BASED ON BACTERIOPHAGES TO ENSURE FOOD SAFETY

Author

P.V. Kulach, V.N. Feklisova, A.I. Laishevtsev, and I.M. Nityaga

Subjects
Preservative, Waste management, business.industry, Food safety, business, Industrial and Manufacturing Engineering
Abstract

The article presents the results of microbiological studies of minced meat from various manufacturers, after processing it with antibacterial agents based on bacteriophages.

Published
2021
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5. VETERINARY AND SANITARY CHARACTERISTIC OF THE QUALITY OF RAW BEEF ON RUSSIAN STORES

Author

P.V. Kulach and V.E. Glushkova

Subjects
Agricultural science, media_common.quotation_subject, Raw beef, Quality (business), Business, Industrial and Manufacturing Engineering, media_common
Abstract

Тhe article presents the results of microbiological studies of raw beef from various manufacturers. The results of studies indicate that in violation of sanitary norms and technological regimes, it is possible to detect pathogens of food toxicoinfection. Ripening of dry-cured products is a complex of interdependent microbiological, chemical and physical processes that determine the quality of the finished product and its safety.

Published
2021
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11. VETERINARY AND SANITARY ASSESSMENT OF THE QUALITY OF FARM-MADE SAUSAGE PRODUCTS

Author

M.I. Shopinskaya, I.M. Nityaga, and P.V. Kulach

Subjects
Agricultural science, media_common.quotation_subject, Quality (business), Business, Industrial and Manufacturing Engineering, media_common
Abstract

The article presents the results of laboratory studies of farm-made sausage products. The results of microbiological studies of sausages indicate that the product does not contain pathogens of food-borne disease and toxicosis, as well as another pathogenic microflora. This indicates high parameters of sausage production, sanitary indicators of raw materials, good sanitary condition of technical equipment and premises of the sausage shop in compliance with technical conditions of heat treatment of products.

Published
2020
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14. THE MAIN DIRECTIONS OF PERSPECTIVE DEVELOPMENT OF BEEKEEPING IN THE RUSSIAN FEDERATION TAKING INTO ACCOUNT REQUIREMENTS OF INTERNATIONAL LEGISLATION

Author

Y.M. Subbotina, M. I. Shopinskaya, E.A. Samakorova, A.A. Ilyukhina, P. V. Kulach, and L. P. Satyukova

Subjects
Beekeeping, business.industry, Political science, Perspective (graphical), food and beverages, Legislation, Russian federation, International trade, business, Industrial and Manufacturing Engineering
Abstract

Recently, more and more people are paying attention to healthy lifestyle, including nutrition, giving preference to natural products. One of these products is honey. The chemical composition of honey is represented by a large number of nutrients: easily digestible carbohydrates, amino acids, enzymes, minerals, vitamins, organic acids, causing its nutritional, dietary¬, and medicinal properties. In the article, the authors analyzed the state of honey production in the country, reflected the share of imports in the market and the share of exports in production, the main factors affecting the honey market are investigated. Based on the results of studies of honey from different regions of the Russian Federation and the requirements of international legislation on product safety, the authors have developed proposals to improve the competitiveness of hive products, both in domestic and foreign markets.

Published
2019
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20. THE USE OF THE DRUG «JODЕS» TO REDUCE BACTERIAL CONTAMINATION OF EGGS

Author

M.I. Shopinskaya, P.V. Kulach, I. D. Kirpichev, and I.M. Nityaga

Subjects
Drug, business.industry, Eggs, media_common.quotation_subject, Contamination, Industrial and Manufacturing Engineering, Disinfection, Toxicology, Immersion, Medicine, Spraying, business, Bacterial contamination, The drug «Jodes», media_common
Abstract

In conditions of modern industrial poultry eggs are often contaminated with enteropathogens, on the surface of the shell there are such microbes as Salmonella, staphylococci and streptococci, intestinal and Pseudomonas aeruginosa sticks, Proteus, fungi, etc. Most industrial poultry farms are integrated enterprises operating on the principle of «vertical communication », which is characterized by significant concentration of poultry in limited areas, this in turn leads to sharp increasing of number of microorganisms on the egg surface, as well as an increase of their pathogenicity. The search for new effective and cost-safe drugs that meet all modern requirements is an actual and economically justified scientific direction. The aim of the present research was to develop effective modes and technologies of disinfection of eggs shell surface by preparation «Jodеs». As a result of the conducted research, high contamination of the shell by microflora, including CGB and mold fungi, was established. The regimes and technology of disinfection of eggs using the disinfectant «Jodеs» in 1% concentration were developed: with small – scale irrigation (wet disinfection method) – exposure for 3 hours; and full immersion for few seconds. It is established that the drug «Jodеs» in 1% concentration effectively sanitize the surface of the shell. Using this drug and compliance with its application can achieve protection of poultry from unwanted microflora.

Published
2018
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23. ОСНОВНЫЕ НАПРАВЛЕНИЯ ПЕРСПЕКТИВНОГО РАЗВИТИЯ ПЧЕЛОВОДСТВА В РОССИЙСКОЙ ФЕДЕРАЦИИ С УЧЕТОМ ТРЕБОВАНИЙ МЕЖДУНАРОДНОГО ЗАКОНОДАТЕЛЬСТВА

Author

Satyukova, L.P., Shopinskaya, M.I., Subbotina, Y.M., Kulach, P.V., Ilyukhina, A.A., and Samakorova, E.A.

Subjects
food and beverages
Abstract

Recently, more and more people are paying attention to healthy lifestyle, including nutrition, giving preference to natural products. One of these products is honey. The chemical composition of honey is represented by a large number of nutrients: easily digestible carbohydrates, amino acids, enzymes, minerals, vitamins, organic acids, causing its nutritional, dietary, and medicinal properties. In the article, the authors analyzed the state of honey production in the country, reflected the share of imports in the market and the share of exports in production, the main factors affecting the honey market are investigated. Based on the results of studies of honey from different regions of the Russian Federation and the requirements of international legislation on product safety, the authors have developed proposals to improve the competitiveness of hive products, both in domestic and foreign markets., В последнее время все больше людей уделяет внимание здоровому образу жизни, в том и числе и питанию, отдавая при этом предпочтение натуральным продуктам. Одним из таких продуктов является мед. Химический состав меда очень богат: в него входят легкоусвояемые углеводы, аминокислоты, ферменты, минеральные вещества, витамины, органические кислоты, обусловливающие его питательные, диетические и лечебные свойства. В статье авторами проведен анализ состояния производства меда в стране, отражена доля импорта в объеме рынка и доля экспорта в объеме производства, изучены основные факторы, влияющие на рынок меда. На основе результатов проведенных исследований меда из различных регионов РФ и требований международного законодательства в отношении безопасности продукта авторами разработаны предложения по повышению конкурентоспособности продукции пчеловодства как на отечественных, так и на зарубежных рынках.

Published
2019
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24. VETERINARY AND SANITARY EVALUATION, AND INCREASING DUCK MEAT PRODUCTION AT POULTRY ENTERPRISES

Author

A. I. Vishnyakov, M. I. Shopinskaya, L. P. Satyukova, and P. V. Kulach

Subjects
Agricultural science, animal structures, animal diseases, virus diseases, Production (economics), Business, Industrial and Manufacturing Engineering
Abstract

In recent years, interest in waterfowl breeding has been growing around the world. Ducks are very promising type of agricultural poultry, and the economic feasibility of their breeding is due to a simplified, controlled environment and high-quality products. Duck meat is one of the most valuable protein products, providing necessary proteins, lipids, minerals and vitamins. The authors describe the state of this type of poultry farming in the domestic market and abroad, and also provide statistics on the consumption of duck meat and characterize its consumer properties.

Published
2019
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25. P6211Efficacy of comprehensive Managed Care after Acute Myocardial Infarction (MC-AMI) in a long-term follow-up - preliminary experience of a single high-volume center

Author

Wita, K, primary, Wilkosz, K, additional, Wita, M, additional, Kulach, A, additional, Wybraniec, M, additional, Polak, M, additional, Matla, M, additional, Maciejewski, L, additional, Skowerski, T, additional, Fluder, J, additional, Kalanska-Lukasik, B, additional, Gomulka, S, additional, Turski, M, additional, and Szydlo, K, additional

Published
2019
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26. A QUESTIONNAIRE-BASED, MULTICENTER REGISTRY OF RESISTANT AND PSEUDO-RESISTANT ARTERIAL HYPERTENSION IN POLAND – A PILOT STUDY

Author

Kulach, Andrzej, primary, Stachowiak, Paweł, additional, Prasal, Marek, additional, Sawicka, Katarzyna, additional, Kosmala, Wojciech, additional, Kosior, Dariusz, additional, Kasprzak, Jarosław D, additional, Skowerski, Mariusz, additional, Sobkowicz, Bożena, additional, Sinkiewicz, Władysław, additional, Płońska-Gościniak, Edyta, additional, Stępień, Miłosz, additional, and Mizia-Stec, Katarzyna, additional

Published
2019
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27. P6217Managed Care after Acute Myocardial Infarction (MC-AMI) reduces MACE by 45% in 3-month follow-up - results form Poland's National Health Fund program of post-MI care. A single center analysis

Author

Kulach, A, primary, Wita, K, additional, Wita, M, additional, Wybraniec, M, additional, Wilkosz, K, additional, Polak, M, additional, Matla, M, additional, Maciejewski, Ł, additional, Skowerski, T, additional, Fluder, J, additional, Kalanska-Lukasik, B, additional, Gomulka, S, additional, and Szydlo, K, additional

Published
2019
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29. Poster session III * Friday 10 December 2010, 08:30-12:30

Author

D. Guldbrand, O. Goetzsche, B. Eika, N. Watanabe, M. Taniguchi, T. Akagi, N. Koide, S. Sano, B. Orbovic, B. Obrenovic-Kircanski, S. Ristic, L. J. Soskic, F. Alhabshan, A. Jijeh, H. Abo Remsh, A. Alkhaldi, H. K. Najm, Z. Gasior, M. Skowerski, A. Kulach, L. Szymanski, M. Sosnowski, M. Wang, C. W. Siu, K. Lee, W. S. Yue, G. H. Yan, S. Lee, C. P. Lau, H. F. Tse, K. O'connor, M. Rosca, J. Magne, G. Romano, M. Moonen, L. A. Pierard, P. Lancellotti, M. Floria, L. De Roy, D. Blommaert, J. Jamart, F. Dormal, M. Lacrosse, C. Arsenescu Georgescu, V. Mizariene, S. Bucyte, A. Bertasiute, E. Pociute, D. Zaliaduonyte-Peksiene, K. Baronaite-Dudoniene, R. Sileikiene, J. Vaskelyte, R. Jurkevicius, M. Dencker, O. Thorsson, M. K. Karlsson, C. Linden, P. Wollmer, L. B. Andersen, O. Catalano, M. R. Perotti, E. Colombo, M. De Giorgi, M. Cattaneo, F. Cobelli, S. G. Priori, C. Ober, I. A. Iancu Adrian, P. A. Andreea Parv, C. H. Cadis Horatiu, O. M. Ober Mihai, M. Chmielecki, M. Fijalkowski, R. Galaska, W. Dubaniewicz, L. Lewicki, R. Targonski, D. Ciecwierz, W. Puchalski, A. Koprowski, A. Rynkiewicz, K. Hristova, A. La Gerche, T. Z. Katova, V. Kostova, Y. Simova, A. Kempny, G. P. Diller, S. Orwat, G. Kaleschke, G. Kerckhoff, R. Schmidt, R. M. Radke, H. Baumgartner, K. Smarz, B. Zaborska, T. Jaxa-Chamiec, P. Maciejewski, A. Budaj, A. Kiotsekoglou, S. C. Govind, V. Gadiyaram, J. C. Moggridge, M. Govindan, A. S. Gopal, S. S. Ramesh, L. A. Brodin, S. K. Saha, I. S. Ramzy, P. Lindqvist, Y. Y. Lam, A. M. Duncan, M. Y. Henein, I. S. Craciunescu, M. Serban, M. Iancu, C. Revnic, B. A. Popescu, D. Alexandru, D. Rogoz, V. Uscatescu, C. Ginghina, G. Careri, A. Di Monaco, R. Nerla, P. Tarzia, P. Lamendola, A. Sestito, G. A. Lanza, F. Crea, F. Giannini, B. Pinamonti, S. Santangelo, A. Perkan, G. Vitrella, S. Rakar, M. Merlo, E. Della Grazia, A. Salvi, G. Sinagra, P. Scislo, J. Kochanowski, R. Piatkowski, M. Roik, M. Postula, G. Opolski, J. Castillo, N. Herszkowicz, C. Ferreira, M. T. Lonnebakken, E. M. Staal, J. E. Nordrehaug, E. Gerdts, M. Przewlocka-Kosmala, A. Orda, B. Karolko, G. Bajraktari, U. Gustafsson, A. Holmgren, S. Frattini, P. Faggiano, V. Zilioli, E. Locantore, S. Longhi, F. Bellandi, G. Faden, M. Triggiani, L. Dei Cas, S. M. Seo, H. O. Jung, S. H. An, S. Y. Jung, C. S. Park, H. K. Jeon, H. J. Youn, W. B. Chung, J. H. Kim, J. S. Uhm, W. Mampuya, M. C. Brochu, D. H. Do, B. Essadiqi, P. Farand, S. Lepage, M. J. Daly, M. Monaghan, A. Hamilton, C. Lockhart, V. Kodoth, C. Maguire, A. Morton, G. Manoharan, M. S. Spence, W. Streb, K. Mitrega, J. Nowak, A. Duszanska, M. Szulik, M. Kalinowski, T. Kukulski, Z. Kalarus, F. E. Calvo Iglesias, I. Solla-Ruiz, I. Villanueva-Benito, E. Paredes-Galan, M. Bravo-Amaro, A. Iniguez-Romo, O. Yildirimturk, F. F. Helvacioglu, Y. Tayyareci, S. Yurdakul, I. C. Demiroglu, S. Aytekin, R. Enache, R. Piazza, D. Muraru, A. Roman-Pognuz, A. Calin, E. Leiballi, F. Antonini-Canterin, G. L. Nicolosi, C. Ridard, A. Bellouin, C. Thebault, M. Laurent, E. Donal, A. Sutandar, B. B. Siswanto, I. Irmalita, G. Harimurti, A. Saxena, S. Ramakrishnan, A. Roy, A. Krishnan, P. Misra, B. Bhargava, P. A. Poole-Wilson, B. B. Loegstrup, H. R. Andersen, S. H. Poulsen, K. E. Klaaborg, H. E. Egeblad, X. Gu, X. Y. Gu, Y. H. He, Z. A. Li, J. C. Han, J. Chen, N. Mansencal, E. Mitry, P. Rougier, O. Dubourg, H. Villarraga, K. Adjei-Twum, T. K. M. Cudjoe, A. Clavell, R. M. Schears, F. Cabrera Bueno, M. J. Molina Mora, J. Fernandez Pastor, A. Linde Estrella, J. L. Pena Hernandez, G. Isasti Aizpurua, F. Carrasco Chinchilla, A. Barrera Cordero, F. J. Alzueta Rodriguez, E. De Teresa Galvan, G. C. Gaetano Contegiacomo, F. P. Francesco Pollice, P. P. Paolo Pollice, M. C. Kontos, D. H. Shin, S. Y. Yoo, C. K. Lee, J. K. Jang, S. I. Jung, S. I. Song, S. I. Seo, S. S. Cheong, J. Peteiro, A. Perez-Perez, A. Bouzas-Mosquera, M. Pineiro, P. Pazos, R. Campo, A. Castro-Beiras, N. Gaibazzi, F. Rigo, D. Sartorio, C. Reverberi, S. Sitia, L. Tomasoni, L. Gianturco, L. Ghio, D. Stella, P. Greco, V. De Gennaro Colonna, M. Turiel, S. Cicala, V. Magagnin, E. Caiani, S. Kyrzopoulos, D. Tsiapras, G. Domproglou, E. Avramidou, V. Voudris, K. Wierzbowska-Drabik, P. Lipiec, L. Chrzanowski, N. Roszczyk, K. Kupczynska, J. D. Kasprzak, V. Sachpekidis, A. Bhan, S. Gianstefani, J. Reiken, M. Paul, P. Pearson, D. Harries, M. J. Monaghan, K. Dale, A. Stoylen, V. Kodali, R. Toole, P. Raju, R. A. Mcintosh, J. Silberbauer, O. Baumann, N. R. Patel, N. Sulke, U. Trivedi, J. Hyde, G. Venn, G. Lloyd, P. Wejner-Mik, K. Wierzbowska, J. A. Lowenstein, C. Caniggia, A. Garcia, M. Amor, N. Casso, D. Lowenstein Haber, C. Porley, G. Zambrana, V. Daru, M. Deljanin Ilic, S. Ilic, D. Kalimanovska Ostric, V. Stoickov, M. Zdravkovic, I. Paraskevaidis, I. Ikonomidis, J. Parissis, C. Papadopoulos, V. Stasinos, V. Bistola, M. Anastasiou-Nana, M. Gudin Uriel, J. R. Balaguer Malfagon, J. L. Perez Bosca, F. Ridocci Soriano, N. Martinez Alzamora, R. Paya Serrano, Q. Ciampi, L. Pratali, M. Della Porta, B. Petruzziello, B. Villari, E. Picano, R. Sicari, A. Rosner, D. Avenarius, S. Malm, A. Iqbal, A. Baltabaeva, G. R. Sutherland, B. Bijnens, T. Myrmel, M. Andersen, F. Gustafsson, N. H. Secher, P. Brassard, A. S. Jensen, C. Hassager, P. L. Madsen, J. E. Moller, M. Coutu, D. Greentree, D. Normandin, H. Brun, A. Dipchand, L. Koopman, C. T. Fackoury, S. Truong, C. Manlhiot, L. Mertens, M. Baroni, M. Mariani, H. K. Chabane, S. Berti, A. Ripoli, S. Storti, M. Glauber, P. A. Scopelliti, G. B. Antongiovanni, D. Personeni, A. Saino, M. Tespili, P. Jung, M. Mueller, F. Jander, H. Y. Sohn, J. Rieber, P. Schneider, V. Klauss, E. Agricola, M. Slavich, S. Stella, M. Ancona, M. Oppizzi, L. Bertoglio, G. Melissano, A. Margonato, R. Chiesa, L. Cejudo Diaz Del Campo, D. Mesa Rubio, M. Ruiz Ortiz, M. Delgado Ortega, E. Villanueva Fernandez, J. Lopez Aguilera, F. Toledano Delgado, M. Pan Alvarez-Ossorio, J. Suarez De Lezo Cruz Conde, M. Lafuente, T. Butz, A. Meissner, C. N. Lang, M. W. Prull, G. Plehn, H. J. Trappe, S. V. Nair, L. Lee, I. Mcleod, G. Whyte, J. Shrimpton, D. Hildick Smith, P. R. James, J. Slikkerveer, Y. E. A. Appelman, G. Veen, T. R. Porter, O. Kamp, P. Colonna, F. J. Ten Cate, D. Bokor, A. Daponte, M. Cocciolo, M. Bona, S. Sacchi, H. Becher, S. C. Chai, P. J. Tan, Y. S. Goh, S. H. Ong, J. Chow, L. L. Lee, P. P. Goh, K. L. Tong, R. Kakihara, C. Naruse, H. Hironaka, T. Tsuzuku, K. Ozawa, A. Tomaszuk-Kazberuk, B. Sobkowicz, J. Malyszko, J. S. Malyszko, R. Sawicki, T. Hirnle, S. Dobrzycki, M. Mysliwiec, W. J. Musial, W. Mathias, I. Kowatsch, A. L. R. Saroute, A. F. F. Osorio, J. C. N. Sbano, J. A. F. Ramires, J. M. Tsutsui, K. Sakata, H. Ito, K. Ishii, T. Sakuma, K. Iwakura, H. Yoshino, J. Yoshikawa, K. Shahgaldi, A. Lopez, B. Fernstrom, A. Sahlen, R. Winter, S. Kovalova, J. Necas, B. H. Amundsen, R. Jasaityte, G. Kiss, D. Barbosa, J. D'hooge, H. Torp, C. A. Szmigielski, J. D. Newton, K. Rajpoot, J. A. Noble, R. Kerber, L. P. Koopman, C. Slorach, N. Chahal, W. Hui, T. Sarkola, T. J. Bradley, E. T. Jaeggi, B. W. Mccrindle, A. Staron, M. Jasinski, S. Wos, P. Sengupta, D. Hayat, M. Kloeckner, J. Nahum, C. Dussault, J. L. Dubois Rande, P. Gueret, P. Lim, G. J. King, A. Brown, E. Ho, I. Amuntaser, K. Bennet, N. Mc Elhome, R. T. Murphy, R. M. Cooper, J. D. Somauroo, R. E. Shave, K. L. Williams, J. Forster, C. George, T. Bett, K. P. George, A. D'andrea, L. Riegler, R. Cocchia, E. Golia, R. Gravino, G. Salerno, R. Citro, P. I. O. Caso, E. Bossone, R. Calabro', F. Crispi, F. Figueras, J. Bartrons, E. Eixarch, F. Le Noble, A. Ahmed, E. Gratacos, Q. Shang, W. K. Yip, L. S. Tam, Q. Zhang, C. M. Li, T. Wang, C. Y. Ma, K. M. Li, C. M. Yu, T. Dahlslett, I. Helland, T. Edvardsen, H. Skulstad, L. S. Magda, M. Florescu, A. Ciobanu, R. Dulgheru, R. Mincu, D. Vinereanu, M. Luckie, S. Chacko, S. Nair, M. Mamas, R. S. Khattar, M. El-Omar, A. Kuch-Wocial, P. Pruszczyk, M. Szulc, G. Styczynski, M. Sinski, A. Kaczynska, Z. Vela, E. Haliti, V. Hyseni, R. Olloni, N. Rexhepaj, S. Elezi, J. J. Onaindia, O. Quintana, A. Cacicedo, S. Velasco, J. J. Alarcon, M. Morillas, J. R. Rumoroso, J. Zumalde, I. Lekuona, E. Laraudogoitia Zaldumbide, A. Poniku, A. Ahmeti, R. F. Duncan, J. M. Mccomb, J. Pemberton, S. W. Lord, D. Leong, C. Plummer, G. Macgowan, N. Grubb, M. Leung, A. Kenny, C. Prinz, J. U. Voigt, A. Zaidi, M. Heatley, S. Z. Abildstrom, A. Hvelplund, J. Berning, S. Govind, L. Brodin, A. Gopal, B. Castaldi, G. Di Salvo, G. Santoro, G. Gaio, M. T. Palladino, C. Iacono, G. Pacileo, M. G. Russo, R. Calabro, Y. S. Wang, L. L. Dong, X. H. Shu, C. Z. Pan, D. X. Zhou, T. Sen, O. Tufekcioglu, M. Ozdemir, A. Tuncez, B. Uygur, Z. Golbasi, H. Kisacik, L. Delfino, F. D. De Leo, L. C. Chiappa, B. Abdel Ghani, R. Schiavina, P. Salvade, A. Morganti, F. Bedogni, P. Mahia, L. Gutierrez, V. Pineda, B. Garcia, I. Otaegui, J. F. Rodriguez, M. T. Gonzalez, M. Descalzo, A. Evangelista, D. Garcia-Dorado, H. A. C. M. Bruin De- Bon, R. B. A. Van Den Brink, S. Surie, P. Bresser, J. Vleugels, H. M. Eckmann, D. A. Samson, B. J. Bouma, C. Dedobbeleer, M. Antoine, M. Remmelink, P. Unger, B. Roosens, I. Hmila, S. Hernot, S. Droogmans, G. Van Camp, T. Lahoutte, S. Muyldermans, B. Cosyns, G. Feltes, V. Serra, O. Azevedo, J. Barbado, J. Herrera, A. Rivera, J. Paniagua, V. Valverde, J. Torras, G. Arriba, T. Christodoulides, M. Ioannides, K. Simamonian, K. Yiangou, M. Myrianthefs, E. Nicolaides, M. Pandolfo, S. A. Kleijn, M. F. A. A. Aly, C. B. Terwee, A. C. Van Rossum, V. Delgado, M. Shanks, H. M. Siebelink, A. Sieders, H. Lamb, N. Ajmone Marsan, J. Westenberg, A. De Roos, J. D. Schuijf, J. J. Bax, A. M. Anwar, Y. Nosir, H. Chamsi-Pasha, H. D. Tschernich, J. Seeburger, M. Borger, C. Mukherjee, F. W. Mohr, J. Ender, K. Obase, H. Okura, R. Yamada, Y. Miyamoto, K. Saito, K. Imai, A. Hayashida, and K. Yoshida

Subjects
medicine.medical_specialty, business.industry, Physical therapy, Medicine, Radiology, Nuclear Medicine and imaging, General Medicine, Session (computer science), Cardiology and Cardiovascular Medicine, business
Published
2010
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31. Repolarization parameters in patients with acute ST segment elevation myocardial infarction treated with primary percutaneous coronary intervention with respect to predischarge ST-T pattern: a preliminary study

Author

Krzysztof, Szydło, Krystian, Wita, Maria, Trusz-Gluza, Karolina, Zawada, Anna, Piecuch, Anna, Kulach, Ewa, Kucz, Anna, Tyrka, Iga, Kornacka, Patrycja, Trams-Stawowska, and Grzegorz, Pieda

Subjects
Male, Time Factors, Myocardial Infarction, Action Potentials, Pilot Projects, Stroke Volume, Coronary Artery Disease, Middle Aged, Patient Discharge, Ventricular Function, Left, Treatment Outcome, Heart Conduction System, Heart Rate, Predictive Value of Tests, Electrocardiography, Ambulatory, Humans, Female, Angioplasty, Balloon, Coronary, Aged
Abstract

Negative T wave and lack of ST segment elevation in predischarge ECG in ST-segment elevation myocardial infraction (STEMI) patients are given as markers of good prognosis. Repolarization duration, especially its late part (TpeakTend - TpTe), likewise ST-T patterns, is related to local post-myocardial infarction myocardial attributes. We analyzed the differences in QT parameters in STEMI patients with negative or not-negative T wave pattern in predischarge ECG.The data from 83 STEMI patients (LVEF45%, first MI, one-vessel disease) who underwent successful percutaneous coronary intervention of infarct-related coronary artery (TIMI 3 flow) were collected. According to ST-T patterns in predischarge ECG, the cohort was divided into two groups: 38 patients with persistent ST elevation and/or non-negative T wave pattern (STT+), and 45 patients with negative T wave, without ST elevation (STT-). QT, QTpeak, and TpTe intervals were obtained from 5 consecutive beats of sinus rhythm 60-70 bpm between 6 a.m. and 8 a.m. from Holter recording, corrected to the heart rate (HR) with Bazett's formula.The study groups did not differ in gender, age, or treatment. No true antiarrhythmics were given. Both QTc and TpTec were longer in STT+ patients: 459 +/- 26 ms vs. 440 +/- 25 ms, p = 0.01 and 108 +/- 10 ms vs. 96 +/- 11 ms, p = 0.000015, respectively. Prolongation of late repolarization was found both in anterior and inferior infarction.STEMI patients who underwent successful percutaneous coronary intervention of infarct-related coronary arteries and demonstrated persistent ST elevation, without negative T wave at hospital discharge, had a longer repolarization duration, especially the late phase of it. Further studies are necessary to assess the prognostic value of this finding.

Published
2009

32. Implementation of the Web Module for Intelligent Housing System based on a single-chip microcomputer

Author

B. Kulach and Krzysztof Tokarz

Subjects
Computer science, computer.internet_protocol, business.industry, Intelligent decision support system, computer.software_genre, World Wide Web, Internet protocol suite, Software, Home automation, Server, Operating system, The Internet, Layer (object-oriented design), Interrupt, business, computer
Abstract

This article broaches the sample implementation of the WWW Module for Intelligent Housing system, based on a single-chip, 8-bit microcomputer, which was scope of the master diploma thesis of one of the authors. It describes both the hardware and software part of the module with special focus on the solution of pseudo-parallel processing of network data, including the way of handling many network connections to the server at the same time. The authors consider the use of embedded interrupt system as a base of a time-division multiplexing (TDM) software layer developed and describe the developed version of minimal TCP/IP stack (so called microstack), with an overview of all protocols implemented. Also the implementation of a simple WWW server with capability to interact with module inputs and outputs is being discussed, as well as the possibility of interaction with other Intelligent Housing modules connected to the Module. The article shows exemplary applications of the mentioned Web Module and delivers information about ways of extending the Web Modulepsilas functionality.

Published
2008
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33. ANTHROPOGENIC AND NATURAL TOXICANTS OF RAW MATERIAL, FOOD PRODUCTS AND MODERN METHODS OF THEIR CONTROL.

Author

NITYAGA, INGA M., USHA, BORIS V., MASHENTSEVA, NATALIA G., KULACH, POLINA V., and LUTSAY, VLADIMIR I.

Subjects
ANTHROPOGENIC effects on nature, RAW materials, MICROBIAL contamination, GOVERNMENT policy, PREVENTION
Abstract

A continually expanding arsenal of anthropogenic and natural toxicants regulated in raw materials, food products, animal feed, in various veterinary surveillance facilities and food production facilities requires the development and implementation of accelerated methods and test systems that simultaneously determine several safety indicators. The risks associated with the safety of raw materials and food products can be attributed to contamination by anthropogenic or natural toxicants. The first include toxic elements, dioxins, synthetic plant growth regulators, substances used in animal husbandry: medicines (antibacterial, antiparasitic and hormonal drugs), phosphorus-and-chloroorganic pesticides, etc. To the second - toxins and metabolites of bacteria, fungi, plants. In order to prevent these risks, the control of these pollutants is carried out. Solving this problem will help the introduction of promising and highly effective methods. The aim of the work was to carry out an experimental and theoretical evaluation of some methods for accelerated control of anthropogenic and natural toxicants. As a result of the conducted studies, the analysis of international and Russian legal and regulatory documents on the criteria for the safety of raw materials and food products is given. The prospects of methods and test systems based on immunomicrochip technology, immunochromatographic indicator elements and PCR in "real time" mode with the use of robotics for accelerated control of anthropogenic and natural toxicants have been experimentally proved. As a result of the studies, the possibility of determining organophosphorus pesticides and pesticides from the class of imidazoles in plant foods and water has been demonstrated, based on the inhibition of acetylcholine-esterase activity with a colorimetric determination of the final result on a vertical photometer as well as immunomicrochip technology. It has been shown that immunochromatographic indicator elements with colloidal gold nanoparticles (IIEC) are promising for screening control of natural toxicants: microorganisms, toxins of bacteria and fungi. The high sensitivity of the PCR method in real time mode has been proven, and automation makes it promising for controlling bacteria in raw materials or products, especially for hard-to-grow or dangerous microorganisms (salmonella, campylobacteria, causative agents of anthrax, brucellosis, etc.) [ABSTRACT FROM AUTHOR]

Published
2018

34. The risk of atherosclerosis in patients with impaired glucose tolerance

Author

Okopien B, Stachura-Kulach A, Andrzej Kułach, Kowalski J, Zielinski M, Wisniewska-Wanat M, Sierant M, Kalina Z, and Zs, Herman

Subjects
Adult, Glycated Hemoglobin, Lipoproteins, LDL, Arteriosclerosis, Risk Factors, Case-Control Studies, Plasminogen Activator Inhibitor 1, Humans, Enzyme-Linked Immunosorbent Assay, Middle Aged, Glucose Metabolism Disorders, Monocyte Chemoattractant Proteins
Abstract

Glucose metabolism disorders usually coexist with dyslipidemia and coagulation/fibrinolysis disturbances. Increase of insulin resistance followed by hyperinsulinemia leads to enhanced protein synthesis, including production of apolipoproteins. As a result, the structure of Low Density Lipoprotein (LDL) becomes small and dense. This augments lipid infiltration into the arterial wall. Following this process monocyte adhesion to endothelium initiates atherosclerotic injury. One of the markers of this inflammatory reaction is Monocyte Chemoattractant Peptide-1 (MCP-1). A lot of inflammatory mediators affect both oxidative modification of LDL and coagulation processes being responsible for anti-fibrinolytic predominance. Plasminogen Activator Inhibitor-1 (PAI-1) is a marker of this state. Therefore the aim of this study is to evaluate the marker of the oxidation processes (oxLDL) as well as prothrombotic (PAI-1) and inflammatory state (MCP-1) markers in patients with Impaired Glucose Tolerance (IGT).The study was carried out on 16 subjects: 10 with biochemically confirmed IGT and 6 age-matched healthy persons without such disorders. Following tests were performed: OGTT, HbA(1c) level as well as TCh, HDL, LDL and TG. Plasma concentrations of oxLDL, PAI-1 and MCP-1 were measured using ELISA method.In patients with Impaired Glucose Tolerance plasma levels of oxLDL were significantly higher compared to control group (67.6 +/- 0.9 U/l vs. 57.8 +/- 4.0 U/l; p0.01) in spite of LDL levels, which did not reveal such difference. MCP-1 plasma concentration compared to control group occurred to be significantly increased in experimental group as well (156.4 +/- 9.2 ng/ml vs. 125.4 +/- 1.9 ng/ml; p0.05). PAI-1 level revealed most significant difference (84.0 +/- 1.8 ng/ml vs. 43.7 +/- 2.7 ng/ml; p0.0001).It is concluded that patients with Impaired Glucose Tolerance should be considered as a group in which atherogenic modification of lipoproteins occurred. Also plasma inflammatory as well as prothrombotic markers concentration was elevated.

Published
2005

35. An integrated environment for the design, simulation and testing of multidimensional digital filters

Author

C.J. Kulach, N.R. Bartley, and L.T. Bruton

Subjects
Frequency response, Noise (signal processing), Filter (video), business.industry, Computer science, Frequency domain, Jpeg compression, Blocking (statistics), business, Digital filter, Simulation, Computer hardware, Network analysis
Abstract

An environment for the design and simulation of multidimensional (M-D) digital filters is described, consisting of a color real-time video acquisition and display system and an M-D filter analysis and simulation facility. It is capable of performing comprehensive frequency-domain analysis and precisely controlled spatiotemporal-domain simulations from signal-flow-graph descriptions of M-D filters. The Multi-Dimensional Network Analysis Program (MDNAP) demonstrates that the filter successfully removes the moving fence and significantly reduces the noise and blocking effects of JPEG compression. >

Published
2002
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36. A real-time video implementation of a three-dimensional first-order recursive discrete-time filter

Author

L.T. Bruton, N.R. Bartley, and C.J. Kulach

Subjects
Signal processing, Pixel, Computer science, business.industry, Real-time computing, Transfer function, Adaptive filter, Filter design, Discrete time and continuous time, Filter (video), Kernel adaptive filter, business, Digital filter, Computer hardware
Abstract

The design and implementation of a real-time 3D digital filter for video signals are described. The filter implements a completely general 3D, first-order, recursive, discrete-time transfer function at NTSC-video rates (480/spl times/512 pixels, 30 f/s). A fully-parallel systolic structure is chosen based on its short critical path, regularity, local interconnectivity, internal overflow immunity, minimized memory requirements and expandability. The implementation is carried out with discrete logic on PCBs and consists of 634 ICs distributed over 12 modules. A comprehensive workstation-based GUI, which includes a 3D filter-design facility, directly communicates with the filter to control its numerous parameters. The hardware can be further expanded to implement higher orders and 3D real-time adaptive filter algorithms. To our knowledge, this is the first such filter to be reported in the literature.

Published
2002
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37. Real-time 3-dimensional recursive digital filter for video signals

Author

C.J. Kulach, L.T. Bruton, and N.R. Bartley

Subjects
Half-band filter, Voltage-controlled filter, business.industry, Computer science, Real-time computing, Transfer function, Adaptive filter, Filter design, Filter (video), Kernel adaptive filter, business, Digital filter, Computer hardware, Root-raised-cosine filter
Abstract

The design and implementation of a real-time 3D digital filter for video signals is described. The filter implements a completely general 3D, first-order, recursive, discrete-time transfer function at NTSC video-rates (480/spl times/512 pixels, 30 f/s). A fully-parallel systolic structure is chosen based on its short critical path, regularity, local interconnectivity, internal overflow immunity, minimized memory requirements and expandability. The implementation is carried out with discrete logic on PCBs and consists of 634 ICs distributed over 12 modules. A comprehensive workstation-based GUI, which includes a 3D filter-design facility, directly communicates with the filter to control its numerous parameters. The hardware can be further expanded to implement higher orders and 3D real-time adaptive filter algorithms. To our knowledge, this is the first such filter to be reported in the literature.

Published
2002
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39. Poster session III * Friday 10 December 2010, 08:30-12:30

Author

Guldbrand, D., primary, Goetzsche, O., additional, Eika, B., additional, Watanabe, N., additional, Taniguchi, M., additional, Akagi, T., additional, Koide, N., additional, Sano, S., additional, Orbovic, B., additional, Obrenovic-Kircanski, B., additional, Ristic, S., additional, Soskic, L. J., additional, Alhabshan, F., additional, Jijeh, A., additional, Abo Remsh, H., additional, Alkhaldi, A., additional, Najm, H. K., additional, Gasior, Z., additional, Skowerski, M., additional, Kulach, A., additional, Szymanski, L., additional, Sosnowski, M., additional, Wang, M., additional, Siu, C. W., additional, Lee, K., additional, Yue, W. S., additional, Yan, G. H., additional, Lee, S., additional, Lau, C. P., additional, Tse, H. F., additional, O'connor, K., additional, Rosca, M., additional, Magne, J., additional, Romano, G., additional, Moonen, M., additional, Pierard, L. A., additional, Lancellotti, P., additional, Floria, M., additional, De Roy, L., additional, Blommaert, D., additional, Jamart, J., additional, Dormal, F., additional, Lacrosse, M., additional, Arsenescu Georgescu, C., additional, Mizariene, V., additional, Bucyte, S., additional, Bertasiute, A., additional, Pociute, E., additional, Zaliaduonyte-Peksiene, D., additional, Baronaite-Dudoniene, K., additional, Sileikiene, R., additional, Vaskelyte, J., additional, Jurkevicius, R., additional, Dencker, M., additional, Thorsson, O., additional, Karlsson, M. K., additional, Linden, C., additional, Wollmer, P., additional, Andersen, L. B., additional, Catalano, O., additional, Perotti, M. R., additional, Colombo, E., additional, De Giorgi, M., additional, Cattaneo, M., additional, Cobelli, F., additional, Priori, S. G., additional, Ober, C., additional, Iancu Adrian, I. A., additional, Andreea Parv, P. A., additional, Cadis Horatiu, C. H., additional, Ober Mihai, O. M., additional, Chmielecki, M., additional, Fijalkowski, M., additional, Galaska, R., additional, Dubaniewicz, W., additional, Lewicki, L., additional, Targonski, R., additional, Ciecwierz, D., additional, Puchalski, W., additional, Koprowski, A., additional, Rynkiewicz, A., additional, Hristova, K., additional, La Gerche, A., additional, Katova, T. Z., additional, Kostova, V., additional, Simova, Y., additional, Kempny, A., additional, Diller, G. P., additional, Orwat, S., additional, Kaleschke, G., additional, Kerckhoff, G., additional, Schmidt, R., additional, Radke, R. M., additional, Baumgartner, H., additional, Smarz, K., additional, Zaborska, B., additional, Jaxa-Chamiec, T., additional, Maciejewski, P., additional, Budaj, A., additional, Kiotsekoglou, A., additional, Govind, S. C., additional, Gadiyaram, V., additional, Moggridge, J. C., additional, Govindan, M., additional, Gopal, A. S., additional, Ramesh, S. S., additional, Brodin, L. A., additional, Saha, S. K., additional, Ramzy, I. S., additional, Lindqvist, P., additional, Lam, Y. Y., additional, Duncan, A. M., additional, Henein, M. Y., additional, Craciunescu, I. S., additional, Serban, M., additional, Iancu, M., additional, Revnic, C., additional, Popescu, B. A., additional, Alexandru, D., additional, Rogoz, D., additional, Uscatescu, V., additional, Ginghina, C., additional, Careri, G., additional, Di Monaco, A., additional, Nerla, R., additional, Tarzia, P., additional, Lamendola, P., additional, Sestito, A., additional, Lanza, G. A., additional, Crea, F., additional, Giannini, F., additional, Pinamonti, B., additional, Santangelo, S., additional, Perkan, A., additional, Vitrella, G., additional, Rakar, S., additional, Merlo, M., additional, Della Grazia, E., additional, Salvi, A., additional, Sinagra, G., additional, Scislo, P., additional, Kochanowski, J., additional, Piatkowski, R., additional, Roik, M., additional, Postula, M., additional, Opolski, G., additional, Castillo, J., additional, Herszkowicz, N., additional, Ferreira, C., additional, Lonnebakken, M. T., additional, Staal, E. M., additional, Nordrehaug, J. E., additional, Gerdts, E., additional, Przewlocka-Kosmala, M., additional, Orda, A., additional, Karolko, B., additional, Bajraktari, G., additional, Gustafsson, U., additional, Holmgren, A., additional, Frattini, S., additional, Faggiano, P., additional, Zilioli, V., additional, Locantore, E., additional, Longhi, S., additional, Bellandi, F., additional, Faden, G., additional, Triggiani, M., additional, Dei Cas, L., additional, Seo, S. M., additional, Jung, H. O., additional, An, S. H., additional, Jung, S. Y., additional, Park, C. S., additional, Jeon, H. K., additional, Youn, H. J., additional, Chung, W. B., additional, Kim, J. H., additional, Uhm, J. S., additional, Mampuya, W., additional, Brochu, M. C., additional, Do, D. H., additional, Essadiqi, B., additional, Farand, P., additional, Lepage, S., additional, Daly, M. J., additional, Monaghan, M., additional, Hamilton, A., additional, Lockhart, C., additional, Kodoth, V., additional, Maguire, C., additional, Morton, A., additional, Manoharan, G., additional, Spence, M. S., additional, Streb, W., additional, Mitrega, K., additional, Nowak, J., additional, Duszanska, A., additional, Szulik, M., additional, Kalinowski, M., additional, Kukulski, T., additional, Kalarus, Z., additional, Calvo Iglesias, F. E., additional, Solla-Ruiz, I., additional, Villanueva-Benito, I., additional, Paredes-Galan, E., additional, Bravo-Amaro, M., additional, Iniguez-Romo, A., additional, Yildirimturk, O., additional, Helvacioglu, F. F., additional, Tayyareci, Y., additional, Yurdakul, S., additional, Demiroglu, I. C., additional, Aytekin, S., additional, Enache, R., additional, Piazza, R., additional, Muraru, D., additional, Roman-Pognuz, A., additional, Calin, A., additional, Leiballi, E., additional, Antonini-Canterin, F., additional, Nicolosi, G. L., additional, Ridard, C., additional, Bellouin, A., additional, Thebault, C., additional, Laurent, M., additional, Donal, E., additional, Sutandar, A., additional, Siswanto, B. B., additional, Irmalita, I., additional, Harimurti, G., additional, Saxena, A., additional, Ramakrishnan, S., additional, Roy, A., additional, Krishnan, A., additional, Misra, P., additional, Bhargava, B., additional, Poole-Wilson, P. A., additional, Loegstrup, B. B., additional, Andersen, H. R., additional, Poulsen, S. H., additional, Klaaborg, K. E., additional, Egeblad, H. E., additional, Gu, X., additional, Gu, X. Y., additional, He, Y. H., additional, Li, Z. A., additional, Han, J. C., additional, Chen, J., additional, Mansencal, N., additional, Mitry, E., additional, Rougier, P., additional, Dubourg, O., additional, Villarraga, H., additional, Adjei-Twum, K., additional, Cudjoe, T. K. M., additional, Clavell, A., additional, Schears, R. M., additional, Cabrera Bueno, F., additional, Molina Mora, M. J., additional, Fernandez Pastor, J., additional, Linde Estrella, A., additional, Pena Hernandez, J. L., additional, Isasti Aizpurua, G., additional, Carrasco Chinchilla, F., additional, Barrera Cordero, A., additional, Alzueta Rodriguez, F. J., additional, De Teresa Galvan, E., additional, Gaetano Contegiacomo, G. C., additional, Francesco Pollice, F. P., additional, Paolo Pollice, P. P., additional, Kontos, M. C., additional, Shin, D. H., additional, Yoo, S. Y., additional, Lee, C. K., additional, Jang, J. K., additional, Jung, S. I., additional, Song, S. I., additional, Seo, S. I., additional, Cheong, S. S., additional, Peteiro, J., additional, Perez-Perez, A., additional, Bouzas-Mosquera, A., additional, Pineiro, M., additional, Pazos, P., additional, Campo, R., additional, Castro-Beiras, A., additional, Gaibazzi, N., additional, Rigo, F., additional, Sartorio, D., additional, Reverberi, C., additional, Sitia, S., additional, Tomasoni, L., additional, Gianturco, L., additional, Ghio, L., additional, Stella, D., additional, Greco, P., additional, De Gennaro Colonna, V., additional, Turiel, M., additional, Cicala, S., additional, Magagnin, V., additional, Caiani, E., additional, Kyrzopoulos, S., additional, Tsiapras, D., additional, Domproglou, G., additional, Avramidou, E., additional, Voudris, V., additional, Wierzbowska-Drabik, K., additional, Lipiec, P., additional, Chrzanowski, L., additional, Roszczyk, N., additional, Kupczynska, K., additional, Kasprzak, J. D., additional, Sachpekidis, V., additional, Bhan, A., additional, Gianstefani, S., additional, Reiken, J., additional, Paul, M., additional, Pearson, P., additional, Harries, D., additional, Monaghan, M. J., additional, Dale, K., additional, Stoylen, A., additional, Kodali, V., additional, Toole, R., additional, Raju, P., additional, Mcintosh, R. A., additional, Silberbauer, J., additional, Baumann, O., additional, Patel, N. R., additional, Sulke, N., additional, Trivedi, U., additional, Hyde, J., additional, Venn, G., additional, Lloyd, G., additional, Wejner-Mik, P., additional, Wierzbowska, K., additional, Lowenstein, J. A., additional, Caniggia, C., additional, Garcia, A., additional, Amor, M., additional, Casso, N., additional, Lowenstein Haber, D., additional, Porley, C., additional, Zambrana, G., additional, Daru, V., additional, Deljanin Ilic, M., additional, Ilic, S., additional, Kalimanovska Ostric, D., additional, Stoickov, V., additional, Zdravkovic, M., additional, Paraskevaidis, I., additional, Ikonomidis, I., additional, Parissis, J., additional, Papadopoulos, C., additional, Stasinos, V., additional, Bistola, V., additional, Anastasiou-Nana, M., additional, Gudin Uriel, M., additional, Balaguer Malfagon, J. R., additional, Perez Bosca, J. L., additional, Ridocci Soriano, F., additional, Martinez Alzamora, N., additional, Paya Serrano, R., additional, Ciampi, Q., additional, Pratali, L., additional, Della Porta, M., additional, Petruzziello, B., additional, Villari, B., additional, Picano, E., additional, Sicari, R., additional, Rosner, A., additional, Avenarius, D., additional, Malm, S., additional, Iqbal, A., additional, Baltabaeva, A., additional, Sutherland, G. R., additional, Bijnens, B., additional, Myrmel, T., additional, Andersen, M., additional, Gustafsson, F., additional, Secher, N. H., additional, Brassard, P., additional, Jensen, A. S., additional, Hassager, C., additional, Madsen, P. L., additional, Moller, J. E., additional, Coutu, M., additional, Greentree, D., additional, Normandin, D., additional, Brun, H., additional, Dipchand, A., additional, Koopman, L., additional, Fackoury, C. T., additional, Truong, S., additional, Manlhiot, C., additional, Mertens, L., additional, Baroni, M., additional, Mariani, M., additional, Chabane, H. K., additional, Berti, S., additional, Ripoli, A., additional, Storti, S., additional, Glauber, M., additional, Scopelliti, P. A., additional, Antongiovanni, G. B., additional, Personeni, D., additional, Saino, A., additional, Tespili, M., additional, Jung, P., additional, Mueller, M., additional, Jander, F., additional, Sohn, H. 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Published
2010
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48. Trankryptom rodziny TGF-β, jego receptorów i ścieżek sygnałowych u chorych z zaawansowaną chorobą wieńcową oraz po zawale serca.

Author

Dąbek, Józefa, Bochenek, Andrzej, Kulach, Andrzej, Szota, Justyno, and Gąsior, Zbigniew

Abstract

Copyright of Polish Surgery / Chirurgia Polska is the property of VM Medica-VM Group (Via Medica) and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2008

49. Transcriptional Activity of Genes Encoding Interferon γ (IFNγ) and its Receptor Assessed in Peripheral Blood Mononuclear Cells in Patients with Cardiac Syndrome X.

Author

Jozefa Dabek, Andrzej Kulach, Tadeusz Wilczok, Urszula Mazurek, Daniel Jakubowski, and Zbigniew Gasior

Subjects
METABOLIC syndrome, GENE expression, BLOOD cells, CORONARY disease
Abstract

Abstract Background  Cardiac syndrome X is typically characterized by effort induced anginal pain with ST segment depression suggestive of myocardial ischemia and normal coronary arteries at angiography. The possible mechanism that may participate in the pathology of CSX is a microvascular dysfunction related to inflammatory process affecting endothelium. Interferon γ (IFN-γ) is an important cytokine in inflammatory reaction. It acts through its specific receptor composed of 2 subunits IFN-γ R1 (ligand binding) and R2 (signal transduction). The expression and proportion of these subunits influences IFN-γ activity. The aim of the study was to assess the gene expression of IFN-γ and its receptors in peripheral blood mononuclear cells (PBMC) from patients with syndrome X. Methods  The study was carried out in 36 patients aged 44–77 (average 57 years old) with cardiac syndrome X and 23 sex- and age-matched healthy subjects (control group). To evaluate gene expression of IFNγ and its receptor total mRNA was extracted from peripheral blood mononuclear cells (PBMC) and the number of mRNA copies were assessed by quantitive reverse transcriptase polymerase chain reaction (QRT-PCR). Results  We have not observed statistically significant differences in INFγ gene expression between studied group and control. Genes encoding IFNγ receptor subunits showed higher expression in PBMCs from patients with cardiac syndrome X vs control subjects (IFNγR1, 97,244  26,956 c/μg vs 12,120  2,940 c/μg, p p  Conclusion  Variation in transcriptional activity of genes encoding INF-γ receptor subunits may affect function of microvasculature and thereby participate in the pathology of cardiac syndrome X. [ABSTRACT FROM AUTHOR]

Published
2007
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50. Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B): a new potential therapeutic target in atherosclerosis?

Author

Dabek, Józefa, Kulach, Andrzej, and Gasior, Zbigniew

Abstract

Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) is a crucial transcription factor that participates in a number of physiological and pathological conditions, including immune response, apoptosis, carcinogenesis and inflammatory processes. It is involved in the rapid response to various stimuli such as viral and bacterial infections, shear stress, oxidant stress and a number of cytokines. In the pathology of atherosclerosis NF-?B is essential to the cross-talk between cytokines, adhesion molecules and growth factors, leading to atherosclerotic plaque formation, growth and eventual rupture.

Published
2010
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