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2. Probing the pH-dependent prepore to pore transition of Bacillus anthracis protective antigen with differential oxidative protein footprinting

Author

Smedley, James G., III., Sharp, Joshua S., Kuhn, Jeffrey F., and Torner, Kenneth B.

Subjects
Mass spectrometry -- Usage, Bacillus anthracis -- Physiological aspects, Biological sciences, Chemistry
Abstract

The mass spectrometry technique is employed to explain the mechanisms involved in the pH-dependent prepore to pore transition of Bacillus anthracis protective antigen (PA) with differential oxidative protein footprinting (OFPF). The extent of oxidation of different residues is also determined experimentally.

Published
2008

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