221 results on '"Kuehl, Philip J."'
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2. Comparative analysis of high-throughput RNA extraction kits in Naïve Non-Human Primate (NHP) tissues for downstream applications utilizing Xeno Internal Positive Control (IPC)
3. Guidance on Mitigating the Risk of Transmitting Respiratory Infections During Nebulization by the COPD Foundation Nebulizer Consortium
4. HS-GC-FID method for quantification of HFA-152a in cell culture media, and plasma from a range of species and regulatory compliant validations
5. Effect of TRPV4 Antagonist GSK2798745 on Chlorine Gas-Induced Acute Lung Injury in a Swine Model
6. iBCS: 3. A Biopharmaceutics Classification System for Orally Inhaled Drug Products
7. 5-Azacytidine inhaled dry powder formulation profoundly improves pharmacokinetics and efficacy for lung cancer therapy through genome reprogramming
8. Local Treatment of Non-small Cell Lung Cancer with a Spray-Dried Bevacizumab Formulation
9. Discovery of GS-7682, a Novel 4′-Cyano-Modified C-Nucleoside Prodrug with Broad Activity against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys
10. Guidance on Mitigating the Risk of Transmitting Respiratory Infections During Nebulization by the COPD Foundation Nebulizer Consortium
11. Design and validation of an exposure system for efficient inter-animal SARS-CoV-2 airborne transmission in Syrian hamsters
12. Effects of Treatment Delay on Efficacy of Tecovirimat Following Lethal Aerosol Monkeypox Virus Challenge in Cynomolgus Macaques
13. Therapeutic administration of inhaled INS1009, a treprostinil prodrug formulation, inhibits bleomycin-induced pulmonary fibrosis in rats
14. Inhalation delivery of nucleic acid gene therapies in preclinical drug development
15. iBCS: 3. A Biopharmaceutics Classification System for Orally Inhaled Drug Products.
16. Characterization of aerosols from hemp-derived pre-roll joints
17. Pulmonary and Regional Deposition of Nebulized and Dry Powder Aerosols in Ferrets
18. In Memoriam: Dr. Paul B. Myrdal
19. Imaging Pulmonary Drug Delivery
20. Design and validation of an exposure system for efficient inter-animal SARS-CoV-2 airborne transmission in Syrian hamsters
21. Adenovirus type 5 SARS-CoV-2 vaccines delivered orally or intranasally reduced disease severity and transmission in a hamster model
22. Composition of aerosols from thermal degradation of flavors used in ENDS and tobacco products
23. Characterization of respiratory deposition of fluticasone-salmeterol hydrofluoroalkane-134a and hydrofluoroalkane-134a beclomethasone in asthmatic patients
24. iBCS: 2. Mechanistic Modeling of Pulmonary Availability of Inhaled Drugs versus Critical Product Attributes
25. iBCS: 1. Principles and Framework of an Inhalation-Based Biopharmaceutics Classification System
26. Biologic Comparison of Inhaled Insulin Formulations: ExuberaTM and Novel Spray-Dried Engineered Particles of Dextran-10
27. Inhaled remdesivir reduces viral burden in a nonhuman primate model of SARS-CoV-2 infection
28. Particle Dynamics and Bioaerosol Viability of Aerosolized Bacillus Calmette–Guérin Vaccine Using Jet and Vibrating Mesh Clinical Nebulizers
29. Development and Testing of a Spray-Dried Tuberculosis Vaccine Candidate in a Mouse Model
30. Blocking Bcl-2 resolves IL-13–mediated mucous cell hyperplasia in a Bik-dependent manner
31. AUG-3387, a Human-Derived Monoclonal Antibody Neutralizes SARS-CoV-2 Variants and Reduces Viral Load from Therapeutic Treatment of Hamsters In Vivo
32. Oral and intranasal Ad5 SARS-CoV-2 vaccines decrease disease and viral transmission in a golden hamster model
33. NOS-2 Inhibition in Phosgene-Induced Acute Lung Injury
34. Formulation Development and In Vivo Evaluation of a New Dry Powder Formulation of Albuterol Sulphate in Beagle Dogs
35. Particle Dynamics and Bioaerosol Viability of Aerosolized BCG Vaccine Using Jet and Vibrating Mesh Clinical Nebulizers
36. Inhalation delivery dramatically improves the efficacy of topotecan for the treatment of local and distant lung cancer
37. Reducing Aerosol-Related Risk of Transmission in the Era of COVID-19: An Interim Guidance Endorsed by the International Society of Aerosols in Medicine
38. Deposition of Aerosolized Lucinactant in Nonhuman Primates
39. Comparative effects of parent and heated cinnamaldehyde on the function of human iPSC-derived cardiac myocytes
40. Prophylaxis of Mycobacterium tuberculosis H37Rv Infection in a Preclinical Mouse Model via Inhalation of Nebulized Bacteriophage D29
41. Preformulation, formulation, and in vivo efficacy of topically applied Apomine
42. New analytical techniques to facilitate preformulation screening in propellant systems
43. Development of an HPLC method for the analysis of Apomine in a topical cream formulation
44. Inhaled Submicron Particle Paclitaxel (NanoPac) Induces Tumor Regression and Immune Cell Infiltration in an Orthotopic Athymic Nude Rat Model of Non-Small Cell Lung Cancer
45. Pharmacokinetic and pharmacodynamic modeling of gut hormone peptide YY(3–36) after pulmonary delivery
46. Pharmacokinetic Profile of Inhaled Submicron Particle Paclitaxel (NanoPac®) in a Rodent Model
47. Use Behaviors, Dependence, and Nicotine Exposure Associated with Ad Libitum Cigar Smoking
48. Inhalation delivery of topotecan is superior to intravenous exposure for suppressing lung cancer in a preclinical model
49. Pharmacokinetic and pharmacodynamic modeling of gut hormone peptide YY(3–36) after pulmonary delivery.
50. Pharmacokinetic Profile of Inhaled Submicron Particle Paclitaxel (NanoPac®) in a Rodent Model.
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