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Fibromyalgia (FMS) is generally associated with neuropathic pain (NP) because of the neuropathic symptoms frequently observed in patients with FMS. The aim of the study is to evaluate the neuropathic component of FMS with the painDETECT (PD-Q) and Douler Neuropathic 4 (DN4) scales. Female patients diagnosed as FMS according to the American College of Rheumatology’s 2010 FMS criteria and female healthy volunteers are included in the study. After demographic evaluation, the patients and volunteers were asked to fill out Visual Analog Score (VAS), PD-Q, and DN4 scale forms. The Fibromyalgia Impairment Questionnaire (FIQ) evaluated life quality and function. There were 66 patients in the FMS group with a mean age of 46.16± 10.66 and 61 patients in the control group with a mean age of 44.93± 12.72. It was determined that there was a significant difference between the VAS, PD-Q, and DN4 values of FMS and control groups (tVAS = 5,025 p < 0.05, t PD-Q = 5,025 p < 0.05, tDN4 = 7,885 p < 0.05). The mean pain score (VAS) and NP level (DN4 and PD-Q) of FMS patients were significantly higher than healthy individuals. In addition, it was determined that VAS (p = 0.001) and PD-Q (p = 0.046) values were found to be significant predictors of the FIQ values. FMS patients may have pain with a neuropathic component, and it seems useful to evaluate neuropathic characteristics with PD-Q and DN4. If the components of pain are researched carefully, more improvement may be achieved in pain and functional capacity [ABSTRACT FROM AUTHOR]

Objectives: The study aims to delineate the occurrence of musculoskeletal symptoms among COVID-19 patients admitted to hospitals and explore the relationship between interleukin levels and C-reactive protein (CRP). Materials and Methods: A study involving the review of medical records was carried out on 109 patients aged 18 and above who were COVID-19 positive and hospitalized during treatment. Pregnant individuals with severe illnesses or insufficient data were excluded from the analysis. Demographic information and laboratory findings were extracted from a health database from earlier research conducted at the same hospital. The investigation focused on establishing the connection between musculoskeletal manifestations, CRP, and interleukin levels. P values less than 0.05 were accepted as statistically significant. Results: A total of 109 individuals were assessed in this study. Among the patients, 34.86% (n = 38) reported arthralgia, 1.83% (n = 2) had arthritis, 41.28% (n = 45) experienced fatigue, and 32.11% (n = 35) encountered post-COVID-19 syndrome. Notably, no significant correlation was observed between musculoskeletal manifestations, CRP, and interleukin levels (P > 0.05). However, a positive correlation was identified between post-COVID-19 syndrome, fatigue, duration of O2 support, and duration of hospitalization (P < 0.05). Additionally, 54% of the patients were elderly, aged 65 years or older. Furthermore, CRP levels exhibited a positive correlation with the duration of hospitalization, O2 support, history of intensive care, and duration of intensive care (P < 0.05). Regarding interleukin levels, there was a positive correlation between interleukin-6 and CRP levels, duration of hospitalization, and O2 support duration (P < 0.05). No significant correlation was found between interleukin-6 and interleukin-10 levels (P > 0.05). Conclusions: No correlation was observed between musculoskeletal symptoms and levels of CRP and interleukin. It is recommended to monitor individuals who have been hospitalized, elderly, experiencing unusual fatigue, or relying on oxygen support for the development of post-COVID-19 syndrome. [ABSTRACT FROM AUTHOR]

Aim: This study aims to determine the frequency of cervicogenic dizziness in patients suffering from neck pain and observe the efficacy of cervicogenic dizziness (CGD) rehabilitation. Materials and Methods: It was a retrospective study. The patients aged between 18 and 65 who attended the physical medicine and rehabilitation outpatient clinic and suffered from neck pain were included in the study. Pregnant patients with a history of cervical surgery, missing data, or attending the rehabilitation program irregularly were excluded. Demographic data, treatment protocols, laboratory and radiology results, and Dizziness Handicap Inventory Scores in the 1st and 3rd month after rehabilitation were obtained from the health database. The frequency and reasons for cervicogenic dizziness and the efficacy of the rehabilitation program were observed. P<0.05 was considered statistically significant. Results: Totally, 443 patients were analyzed. 288 patients were female, and 155 were male. The mean age was 50.31 ± 14.06. Cervical disc herniation was determined in 40% (n = 178) of the patients, cervical spondylosis was observed in 11.5% (n = 51) of patients, 45.5% (n = 202) of patients had myofascial pain syndrome and 1.5% (n = 6) of patients defined trauma. Neck pain was associated with dizziness in 8.57% (n = 38). Cervicogenic dizziness was determined in 8.1% of the patients, and the most common reasons were myofascial trigger points and cervical disc hernia. Patients who accepted the cervicogenic rehabilitation program had a better Dizziness Handicap Inventory Score in the 1st and 3 rd month controls. Conclusion: Cervicogenic dizziness was determined in 8.1% of patients suffering from neck pain. It was detected that the most common reason was cervical pathologies, and the patients benefited from rehabilitation program. [ABSTRACT FROM AUTHOR]

Introduction: Fibromyalgia is a musculoskeletal disease that is frequently detected in young women, includes symptoms such as fatigue, sleep disturbances, and cognitive dysfunction unrelated to pain, and negatively affects the patient's quality of daily life. Ozone therapy increases tissue oxygenation, activates antioxidant mechanisms, and may be used in patients with fibromyalgia. The aim of this study is to investigate the efficacy of ozone therapy on pain and functional status in fibromyalgia patients., Methods: It was a longitudinal cross-sectional study. The study was performed by Baskent University Alanya Hospital. Patients, aged between 20 and 65 years, diagnosed with fibromyalgia according to American College of Rheumatology 2010 criteria and had ozone therapy were included to the study. It was hypothesized that the ozonetherapy increases tissue oxygenization, decreases pain level and supplies better quality of life in patients with fibromyalgia. Demographic and three-month follow-up data of fibromyalgia patients who had received 10 sessions of ozone autohemotherapy were obtained from the hospital database. The patients received 10 sessions of ozone autohemotherapy at a concentration of 25 µg/ml (100 ml of blood and 100 ml of ozone gas) 2-3 times per week. The values of the Visual Analog Score and Fibromyalgia Impairment Questionnaire scores in the three-month follow-up were statistically compared, and P < .05 was considered statistically significant., Results: 20 female patients were analyzed. The mean age of patients was 54. 8 ± 15. 5 years. Patients' median (min-max) baseline score on Visual Analog Score was 9 (5-10), post-treatment score was 3 (0-8), 3 (1-8) in 1st month, and 4 (1-8) in 3rd month. The median (min-max) Fibromyalgia Impairment Questionnaire score of patients was 73.29 (29.2 - 87.2) at baseline, 31.67 (7.01 - 66.99) after treatment, 24. 6 (10. 7- 63. 3) at 1st month, and 24.67 (10.67- 66.99) 3rd month. A significant decrease in pain (P < .001) and functional improvement (P < .001) was observed in the patients after ozonetherapy., Conclusion: After 10 sessions of ozonetherapy in fibromyalgia patients, the Visual Analog Score and Fibromyalgia Impairment Questionnaire scores decreased significantly and this well-being persisted for three months. Ozonetherapy may be considered for fibromyalgia treatment protocol as complementary therapy. For determining dosage and session standarts further studies are needed.