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790 results on '"Kuchta, Kristine"'

10. The Laparoscopy in Biliary Exploration Research and Training Initiative (LIBERTI) trial: simulator-based training for laparoscopic management of choledocholithiasis

Author

VanDruff, Vanessa N., Santos, B. Fernando, Kuchta, Kristine, Cotter, Robin, Goldwag, Jenaya, Cai, Ming, Fowler, Xavier, Lamb, Casey R., Uyrga, Abigail J., Cutshall, Michael, Davis, Brian R., Lerma, Roxann A., Auyang, Edward D., Li, Wendy, Ceppa, Eugene P., Jones, Edward, Abbitt, Danielle, Amundson, Julia R., Joseph, Stephanie, Hedberg, H. Mason, McCormack, Michael, and Ujiki, Michael B.

Published
2024
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13. Male Breast Cancer Patient and Surgeon Experience: The Male WhySurg Study

Author

Chichura, Anna, Attai, Deanna J, Kuchta, Kristine, Nicholson, Kyra, Kopkash, Katherine, Pesce, Catherine, and Yao, Katharine

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Breast Cancer, Cancer, Clinical Research, Breast Neoplasms, Breast Neoplasms, Male, Female, Humans, Male, Mastectomy, Mastectomy, Segmental, Middle Aged, Surgeons, Surveys and Questionnaires, Oncology & Carcinogenesis, Oncology and carcinogenesis
Abstract

BackgroundLittle is known about the experience of the male breast cancer patient. Mastectomy is often offered despite evidence that breast-conserving surgery (BCS) provides similar outcomes.MethodsTwo concurrent online surveys were distributed from August to October 2020 via social media to male breast cancer (MBC) patients and by email to American Society of Breast Surgeon members. The MBC patients were asked their opinions about their surgery, and the surgeons were asked to provide surgical recommendations for MBC patients.ResultsThe survey involved 63 MBC patients with a mean age of 62 years (range, 31-79 years). Five MBC patients (7.9 %) stated that their surgeon recommended BCS, but 54 (85.7 %) of the patients underwent unilateral, and 8 (12.7 %) underwent bilateral mastectomy. Most of the patients (n = 60, 96.8 %) had no reconstruction. One third of the patients (n = 21, 33.3 %) felt somewhat or very uncomfortable with their appearance after surgery. The response rate was 16.5 % for the surgeons. Of the 438 surgeons who answered the survey, 298 (73.3 %) were female, 215 (51.7 %) were fellowship-trained, and 244 (58.9 %) had been practicing for 16 years or longer. More than half of surgeons (n = 259, 59.1 %) routinely offered BCS to eligible men, and 180 (41.3 %) stated they had performed BCS on a man with breast cancer. Whereas 89 (20.8 %) of the surgeons stated that they routinely offer reconstruction to MBC patients, 87 (20.3 %) said they do not offer reconstruction, 96 (22.4 %) said they offer it only if the patient requests it, and 157 (36.6 %) said they never consider it as an option.ConclusionsThe study found discordance between MBC patients' satisfaction with their surgery and surgeon recommendations and experience. These data present an opportunity to optimize the MBC patient experience.

Published
2022

24. Programmed Death Ligand-1 Combined Positive Score Concordance and Interrater Reliability in Primary Tumors and Synchronous Lymph Node Metastases in Resected Cases of [p16.sup.+] Oropharyngeal Squamous Cell Carcinoma

Author

Kaur, Amandeep, Kuchta, Kristine, Watkin, William, Sullivan, Megan, Liu, Lin, Jamshidi, Pouya, Campbell, Nick, Brockstein, Bruce, and Paintal, Ajit

Subjects
Throat cancer -- Genetic aspects -- Complications and side effects -- Care and treatment, Lymphatic metastasis -- Genetic aspects -- Development and progression -- Care and treatment, Cellular proteins -- Health aspects, Health
Abstract

Context.--Pembrolizumab is used in patients with metastatic head and neck squamous cell carcinoma contingent upon the programmed death ligand-1 (PD-L1) combined positive score (CPS). Objective.--To compare PD-L1 CPS scores derived from paired resected primary tumors (PTs) and lymph node metastases (LMs) in patients with [p16.sup.+] oropharyngeal squamous cell carcinoma (OPSCC). Design.--We identified 38 resected [p16.sup.+] OPSCCs for which paired PTs and LMs were available. PD-L1 immunohistochemistry using the SP263 antibody clone was done on both the PT and the LM. CPS scoring was performed by 4 observers, and data were analyzed at the CPS cut points of greater than or equal to 1 and 20 in regard to interobserver and interspecimen agreement. Results.--Overall agreement between consensus CPS scoring of PT and LM was seen in 76% of paired specimens ([kappa] = 0.53). No specimen received a negative consensus score. Interobserver agreement for both PT and LM was fair to substantial ([kappa] = 0.54 and 0.51, respectively) and was inferior to that seen in a prospective series of unselected head and neck squamous carcinoma cases evaluated at our institution ([kappa] = 0.84). Conclusions.--Given the high rates of interobserver and interspecimen variability, evaluation of additional material or by additional observers may be of value in performing CPS scoring in cases of [p16.sup.+] OPSCC. This is particularly the case when a negative or low-positive result is being evaluated in a patient who is otherwise a good candidate for immunotherapy. doi: 10.5858/arpa.2021-0464-OA, Over the last several years, immune checkpoint inhibitors targeting the programmed death receptor-1 (PD-1)/programmed death ligand-1 (PD-L1) pathway have had a profound impact on the field of oncology. Immune checkpoint [...]

Published
2023
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26. Covid-19 related oncologist’s concerns about breast cancer treatment delays and physician well-being (the CROWN study)

Author

Yao, Katharine A, Attai, Deanna, Bleicher, Richard, Kuchta, Kristine, Moran, Meena, Boughey, Judy, Wilke, Lee G, Dietz, Jill R, Stevens, Randy, Pesce, Catherine, Kopkash, Katherine, Kurtzman, Scott, Sarantou, Terry, and Victorson, David

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Oncology and Carcinogenesis, Cancer, Behavioral and Social Science, Prevention, Breast Cancer, Good Health and Well Being, Anxiety, Breast Neoplasms, Burnout, Professional, COVID-19, Cross-Sectional Studies, Female, Humans, Male, Middle Aged, Oncologists, Sleep, Surgeons, Surveys and Questionnaires, Time-to-Treatment, United States, Breast cancer delays, Physician well being, COVID-19 treatment delays, Oncology & Carcinogenesis, Clinical sciences, Oncology and carcinogenesis
Abstract

PurposeTo examine how treatment delays brought on by the COVID-19 pandemic impacted the physical and emotional well-being of physicians treating these patients.MethodsA cross-sectional survey of physician breast specialists was posted from April 23rd to June 11th, 2020 on membership list serves and social media platforms of the National Accreditation Program for Breast Centers and the American Society of Breast Surgeons. Physician well-being was measured using 6 COVID-19 burnout emotions and the 4-item PROMIS short form for anxiety and sleep disturbance. We examined associations between treatment delays and physician well-being, adjusting for demographic factors, COVID-19 testing and ten COVID-19 pandemic concerns.Results870 physicians completed the survey, 61% were surgeons. The mean age of physicians was 52 and 548 (63.9%) were female. 669 (79.4%) reported some delay in patient care as a result of the COVID-19 pandemic. 384 (44.1%) and 529 (60.8%) of physicians scored outside normal limits for anxiety and sleep disturbance, respectively. After adjusting for demographic factors and COVID-19 testing, mean anxiety and COVID-19 burnout scores were significantly higher among physicians whose patients experienced either delays in surgery, adjuvant chemotherapy, radiation, breast imaging or specialty consultation. A multivariable model adjusting for ten physician COVID-19 concerns and delays showed that "delays will impact my emotional well-being" was the strongest concern associated with anxiety, sleep disturbance and COVID-19 burnout factors.ConclusionsBreast cancer treatment delays during the initial surge of the COVID-19 pandemic in the United States were associated with a negative impact on physician emotional wellness.

Published
2021

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