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115 results on '"Kucher, M."'

9. Mechanisms of central nervous system damage in COVID-19

Author

Rassokhin, V. V., primary, Svetashova, E. I., additional, Shcherbakov, A. A., additional, Polushin, A. Yu., additional, Kucher, M. A., additional, Kazantsev, I. V., additional, Goloshchapov, O. V., additional, Klementieva, R. V., additional, Sinyaev, A. A., additional, Ovechkina, V. N., additional, Lazarev, A. A., additional, Popova, M. O., additional, and Kulagin, A. D., additional

Published
2023
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19. Fecal microbiota transplantation for graft-versus-host disease in children and adults: methods, clinical effects, safety

Author

Goloshchapov, O. V., primary, Chukhlovin, A. B., additional, Bakin, E. A., additional, Stanevich, O. V., additional, Klementeva, R. V., additional, Shcherbakov, A. A., additional, Shvetsov, A. N., additional, Suvorova, M. A., additional, Bondarenko, S. N., additional, Kucher, M. A., additional, Kulagin, A. D., additional, Zubarovskaya, L. S., additional, and Moiseev, I. S., additional

Published
2020
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32. STATISTICAL ASSESSMENT OF SOCIO-ECONOMIC DETERMINATION OF CRIME IN UKRAINE.

Author

Palant, O. Y., Ortina, G. V., and Kucher, M. М.

Subjects
CRIME statistics, CRIME, ECONOMIC determinism, TRANSITION economies, DEVIANT behavior
Abstract

Urgency of the research. One of the topical social problems in the world is the criminalization of society in general and the economy in particular. This problem is most acute in countries with transitional economies. Target setting. In conditions when traditional direct methods of fighting crime are not sufficiently effective, the development of alternative measures of state policy aimed at achieving the desirable results in the sphere of socioeconomic relations is required. Actual scientific researches and issues analysis. The generalization of the conceptual approaches to the study considered in the works [2-6], showed that at the present stage a scientific representation of economic determinism has already been formed. The understanding of the determination of deviant behavior by economic factors has been its basis. Uninvestigated parts of general matters defining. The lack of expanded characteristics, scientific and methodical tools for analyzing the socio-economic determination of crime complicates the processes of establishing the economic determinants, means, cognition forms and methods, formation of a comprehensive program for its prevention and counteraction. The research objective. The main task of the study is to assess the socio-economic determination of crime in Ukraine using econometric methods. The statement of basic materials. The problem of analyzing the socio-economic determination of crime based on the use of econometric models has been studied, the correlation-regression models have been adapted, the applied aspects of the constructed regression equation to solve the problems of crime determination analysis have been considered. Conclusions. The identifying the mechanism of interrelationships of socio-economic phenomena and the criminal situation has theoretical significance and allows to anticipate possible changes in the crime rate in the future in accordance with the predicted changes in socio-economic phenomena. The analysis of such interrelations allows increasing the effectiveness of socio-economic policy measures at the state level. [ABSTRACT FROM AUTHOR]

Published
2018
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33. Development of donor bone marrow registry in Russian Federation: experience of Raisa Gorbacheva Memorial Research Institute of Children Oncology, Hematology and Transplantation

Author

Alyanskiy, A. L., primary, Makarenko, O. A., additional, Ivanova, N. E., additional, Golovacheva, A. A., additional, Kuzmich, E. V., additional, Kucher, M. A., additional, Babenko, E. V., additional, Estrina, M. A., additional, Vitrischak, A. A., additional, Paina, O. V., additional, Petrova, A. L., additional, Pevtsov, D. E., additional, Zubarovskaya, L. S., additional, and Afanasyev, B. V., additional

Published
2016
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34. АВ0-INCOMPATIBILITY IN ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION: 15-YEARS EXPERIENCE OF R.M. GORBACHEVA MEMORIAL RESEARCH INSTITUTE FOR CHILDREN ONCOLOGY, HEMATOLOGY AND TRANSPLANTATION

Author

Kucher, M. A., primary, Pevtcov, D. E., additional, Makarenko, O. A., additional, Alyanskiy, A. L., additional, Ivanova, N. E., additional, Estrina, М. A., additional, Babenko, E. V., additional, Bakhovadinov, B. B., additional, Zubarovskaya, L. S., additional, and Afanasiev, B. V., additional

Published
2016
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46. Methanol and ethanol utilization in methylotrophic yeast Pichia pinuswild-type and mutant strains

Author

Sibirny, A., Titorenko, V., Teslyar, G., Petrushko, V., and Kucher, M.

Abstract

In the wild-type strain of methylotrophic yeast Pichia pinusdiauxic growth is observed during cultivation in medium containing a mixture of methanol and ethanol: firstly, “slow” phase of ethanol utilization is revealed and, secondly, a “fast” phase of methanol consumption is shown. Diauxic growth is observed also in ecr1mutant, impaired in ethanol-induced catabolite repression of methylotrophic metabolism enzymes, but the order of utilization of the alcohols is inverted in this mutant. Such succession of alcohols utilization in both strains correlates well with the sequence of synthesis of microbody enzymes which catalyze key reactions of C1- and C2-metabolism. On the contrary, simultaneous utilization of methanol and ethanol from the mixture, as well as synchronous synthesis of both peroxisomal and glyoxisomal enzymes is observed in adh1mutant which has reduced alcohol dehydrogenase activity. The strong differences between the wild-type strain and adh1mutant were observed also in the kinetics of specific activity changes for C1-metabolizing enzymes, localized in cytosol. In the wild-type strain during growth on methanol and ethanol mixture such changes correlate with the sequence of alcohol utilization. At the same time, in adh1mutant the activities of formaldehyde dehydrogenase and formate dehydrogenase during the growth on the alcohols mixture are as high as during growth on methanol only, but the activity of dihydroxyacetone kinase is as low as under the growth on ethanol and is lower than on methanol.

Published
1991
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