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Anticipating an increasing demand for hybrid double network (DN) hydrogels in biomedicine and biotechnology, this study evaluated the effects of each network on the mechanical and biological properties. Polyethylene glycol (PEG) (meth)acrylate hydrogels with varied monomer molecular weights and architectures (linear vs. 4-arm) were produced with and without an added ionically bonded alginate network and their mechanical properties were characterized using compression testing. The results showed that while some mechanical properties of PEG single network (SN) hydrogels decreased or changed negligibly with increasing molecular weight, the compressive modulus, strength, strain to failure, and toughness of DN hydrogels all significantly increased with increased PEG monomer molecular weight. At a fixed molecular weight (10 kDa), 4-arm PEG SN hydrogels exhibited better overall mechanical performance; however, this benefit was diminished for the corresponding DN hydrogels with comparable strength and toughness and lower strain to failure for the 4-arm case. Regardless of the PEG monomer structure, the alginate network made a relatively larger contribution to the overall DN mechanical properties when the covalent PEG network was looser with a larger mesh size (e.g., for larger monomer molecular weight and/or linear architecture) which presumably enabled more ionic crosslinking. Considering the biological performance, adipose derived stem cell cultures demonstrated monotonically increasing cell area and Yes-associated protein related mechanosensing with increasing amounts of alginate from 0 to 2 wt.%, demonstrating the possibility for using DN hydrogels in guiding musculoskeletal differentiation. These findings will be useful to design suitable hydrogels with controllable mechanical and biological properties for mechanically demanding applications. Statement of significance: Hydrogels are widely used in commercial applications, and recently developed hybrid double network hy

The effects of build orientation and post heat treatments on the tensile and fatigue crack growth (FCG) behavior of commercially pure titanium (CP-Ti) manufactured by laser powder bed fusion (LPBF) using grade 2 powder were examined. Two orthogonal build orientations were used in conjunction with hot isostatic pressing (HIP) both above (950 °C) and below (730 °C) the β-transus temperature and property comparisons were also made to commercially available wrought material. The HIP treatments coarsened the α grain structure, reduced the tensile strength, and increased the fatigue crack growth threshold. The LPBF materials were generally stronger and more fatigue resistant than the wrought material due higher interstitial oxygen and nitrogen content. Additionally, higher tensile strength values were found for one build orientation with higher nitrogen content that was attributed to the different thermal histories during LPBF. However, the build orientation effect was not observed for the FCG behavior of the LPBF material and the FCG resistance at low growth rates were mainly controlled by the grain size. This was in sharp contrast to the wrought material which showed strong anisotropy in the microstructure sensitive fatigue crack growth regime due to strong crystallographic texture. At higher growth rates, FCG became microstructure insensitive when the cyclic plastic zone size became of similar order of magnitude to the grain size.

This short communication presents 2–4 μm sized TiCN reinforced AlSi10Mg composites (TiCN/AlSi10Mg) fabricated by laser powder bed fusion (LPBF) with refined Al-Si eutectic microstructure consisting of equiaxed bi-modal α-Al grains and enhanced elevated temperature tensile strength. The formation mechanism of reported bi-modal structure is related to the modified temperature gradients and induced heterogeneous nucleation in LPBF. The enhancement in elevated temperature tensile strength is mainly attributed to refined bi-modal Al-Si microstructure and thermal stability of TiCN particles.

Zr-based bulk metallic glasses (BMGs) are amorphous alloys that can exhibit excellent mechanical properties, including high yield strength and fracture toughness. These properties are linked to local microstructural heterogeneities. Whether via microscopy-based techniques, synchrotron techniques, or calorimetric approaches, the amorphous structure of BMGs makes the characterisation of the details of these local structural and chemical heterogeneities extremely challenging. Our focus here is on atom probe tomography (APT), where considerable uncertainty remains in terms of how and when to apply this otherwise powerful technique to amorphous materials. This work reports a systematic evaluation of the experimental parameter space. We report results of BMG composition acquired against various APT operating parameters for Zr63.96Cu13.36Ni10.29Al11.04Nb1.25 (at. %). We demonstrate that a customised peak-based ranging approach yields satisfactory compositional accuracy with absolute errors of <1 at. %. Beyond composition, we have discussed the data quality in terms of attributes of the mass spectra: mass resolution, signal-to-thermal tail ratio, and overlapped peak ratio. We also assess the composition of the well-known clustered evaporation effects, common in APT data of BMGs. We conclude that these regions have negligible differences in composition from the surrounding "matrix"or bulk in these alloys.

Background and Aims: The purpose of this investigation was to test the hypothesis that a novel adhesive retention suture device (ARSD) can increase perfusion at elliptical wound closures by distributing stress away from the suture site. Methods: Stress in the skin around a suture both with and without support from an ARSD was evaluated using a finite element model. A single-center, randomized split-scar comparison trial using laser speckle contrast analysis was used to quantify the perfusion at elliptical wound closures in human patients both with and without an ARSD. Results: The finite element model revealed that the ARSD promoted load transfer to the skin over a larger area, thus reducing the local stress and deformation in the skin around the suture site. Results from the split-scar study showed a mean improvement of 25% perfusion units with the ARSD, and the improvement was statistically significant (p = 0.002). Conclusion: The reduction in local stress and enhanced perfusion around the suture site reveals the potential benefit of using an ARSD to enable more efficient healing by avoiding complications associated with both low perfusion and skin tearing, such as dehiscence, infection, and cheese wiring.

The incorporation of mechanosensitive linkages into polymers has led to materials with dynamic force responsivity. Here we report oxanorbornadiene cross-linked double network hydrogels that release molecules through a force-mediated retro Diels-Alder reaction. The molecular design and tough double network of polyacrylamide and alginate promote significantly higher activation at substantially less force than pure polymer systems. Activation at physiologically relevant forces provides scope for instilling dynamic mechanochemical behavior in soft biological materials. This journal is

In this paper, a novel approach is presented to tailor the stress properties of diamond thin films via boron doping and micro-fabrication of bridges using focused ion beam milling. The experimental data, based on detailed confocal micro-Raman investigations, are supported and interpreted through finite element method calculations of the stress distribution at mechanical equilibrium. These results indicate that appropriate design of microbridge geometries, together with boron doping, would allow the material stress to be largely enhanced or diminished compared to non-patterned thin films. Our approach, together with a deterministic incorporation and positioning of diamond color centers, may open novel opportunities to tailor the optical and spin properties of diamond-based quantum devices through stress engineering.

The mechanical performance of a Ni–Mo–Cr (GH3535) alloy weldment, produced using a matching filler metal, was assessed and compared to the surrounding parent metal. Ambient-temperature mechanical characterisation included hardness testing, small punch testing and uniaxial tensile testing, while a crystal plasticity finite element model was used to assess the impact of crystallographic texture on the mechanical properties. Despite the similar chemical composition, the weld metal exhibited superior strength and ductility to that of the parent metal. The higher strength was primarily attributed to the high dislocation density in the weld metal imbued by the welding-induced thermo-mechanical loading. In contrast, the ductility difference was attributed to M6C carbide stringers in the parent metal that initiated fracture at lower strains when compared to the weld metal, with the latter containing finer, well-dispersed M6C carbides.

Developing highly efficient and durable electrocatalysts for hydrogen evolution reaction (HER) under both alkaline and acidic media is crucial for the future development of a hydrogen economy. However, state-of-the-art high-performance electrocatalysts recently developed are based on carbon carriers mediated by binding noble elements and their complicated processing methods are a major impediment to commercialization. Here, inspired by the high-entropy alloy concept with its inherent multinary nature and using a glassy alloy design with its chemical homogeneity and tunability, we present a scalable strategy to alloy five equiatomic elements, PdPtCuNiP, into a high-entropy metallic glass (HEMG) for HER in both alkaline and acidic conditions. Surface dealloying of the HEMG creates a nanosponge-like architecture with nanopores and embedded nanocrystals that provides abundant active sites to achieve outstanding HER activity. The obtained overpotentials at a current density of 10 mA cm−2 are 32 and 62 mV in 1.0 m KOH and 0.5 m H2SO4 solutions, respectively, outperforming most currently available electrocatalysts. Density functional theory reveals that a lattice distortion and the chemical complexity of the nanocrystals lead to a strong synergistic effect on the electronic structure that further stabilizes hydrogen proton adsorption/desorption. This HEMG strategy establishes a new paradigm for designing compositionally complex alloys for electrochemical reactions.

In this study, two sets of optimized laser powder bed fusion (LPBF) additive manufacturing parameters with similar energy density but different laser powers (HP: high laser power with high scanning speed, LP: low laser power with low scanning speed) were used to produce fully dense and crack-free NiTi samples. The microstructure, phase transformation and mechanical properties of the LPBF fabricated HP and LP NiTi were investigated using scanning electron microscopy (SEM), differential scanning calorimeter (DSC), X-ray diffraction (XRD) and dynamic mechanical analysis (DMA). The results showed that the HP and LP NiTi samples had different microstructures, phase transformation temperatures and mechanical properties. It was found that the HP NiTi samples predominantly contained austenite at room temperature and exhibited lower phase transformation temperatures. In contrast, the LP NiTi samples contained a large amount of martensite and had larger thermal memory recovery and better damping capacity. Additionally, the microstructure, phase transformation temperatures and mechanical properties were found to vary at different locations along the building direction in both HP and LP NiTi. This study implies that by manipulating the LPBF processing parameters, in particular the laser power, the phase transformation, microstructure and dynamic mechanical properties of the LPBF fabricated NiTi can be controlled to target different applications.

High strain rate micromechanical testing can assist researchers in elucidating complex deformation mechanisms in advanced material systems. In this work, the interactions of atomic-scale chemistry and strain rate in affecting the deformation response of a Zr-based metallic glass was studied by varying the concentration of oxygen dissolved into the local structure. Compression of micropillars over six decades of strain rate uncovered a remarkable reversal of the strain rate sensitivity from negative to positive above ~ 5 s−1 due to a delocalisation of shear transformation events within the pre-yield linear regime for both samples, while a higher oxygen content was found to generally decrease the strain rate sensitivity effect. It was also identified that the shear band propagation speed increases with the actuation speed, leading to a transition in the deformation behaviour from serrated to apparent non-serrated plastic flow at ~ 5 s−1. Graphic abstract: [Figure not available: see fulltext.]

The combination of refined microstructures (induced by rapid cooling) and melt pool-induced mesostructures in AlSi10Mg fabricated using laser powder bed fusion (LPBF) – a widely used additive manufacturing technique – impart high strength and fracture toughness. Further exploitation of such property combinations requires a detailed understanding of how the processing conditions control the micro- and mesostructures and, in turn, the mechanical performance, especially regarding fracture resistance. Towards this end, the crack resistance curve (R-curve) behavior in different orientations of LPBF-fabricated AlSi10Mg alloys processed with different layer thickness, hatch spacing, and scan strategies was evaluated and correlated with micro- and mesostructural features such as grain size and grain orientation, texture, cell morphology, and melt pool arrangement. Results show a strong anisotropy in both tensile stress-strain behavior and fracture toughness with layer thickness and hatch spacing controlling strength and scan strategy dictating fracture resistance. In terms of tensile stress-strain behavior, the arrangement of melt pool boundaries with respect to loading direction results in anisotropy in ductility whereas strength is controlled by grain size and cellular structure. In case of fracture toughness, measurements show that failure is dominated primarily by melt pool morphology and hence the mesostructure that is controlled by scan strategy. They furthermore reveal, that, despite the pronounced anisotropy in the R-curve behavior the presence of such mesostructure enables a level of damage-tolerance in AlSi10Mg that cannot be achieved in a cast alloy.

Bulk metallic glasses (BMGs) are materials with outstanding strength and elastic properties that make them tantalizing for engineering applications, yet our poor understanding of how their amorphous atomic arrangements control their broader mechanical properties (hardness, wear, fracture, etc.) impedes our ability to apply materials science principles in their design. In this work, we uncover the hierarchical structure that exists in BMGs across the nano- to microscale by using nanobeam electron diffraction experiments. Our findings reveal that local hardness of microscale domains decreases with increasing size and volume fraction of atomic clusters with higher local medium range order (MRO). Furthermore, we propose a model of ductile phase softening that will enable the future design of BMGs by tuning the MRO size and distribution in the nanostructure.

Effects of build orientation (0°, 45°, 90°) and post heat treatments (hot isostatic pressing 820 °C, 950 °C or annealing 1020 °C) on the fatigue crack growth rates (FCGRs) of Ti-6Al-4V fabricated by laser powder bed fusion were examined. Coarser α′/α lath thicknesses resulted in slower FCGRs and higher fatigue thresholds while texture and build orientation had little influence. Fatigue thresholds were defined by the ability to transfer slip from one α′/α lath to another, with a minor role of roughness induced crack closure. The transition away from microstructure sensitive FCG occurred where the packet/colony size equaled the cyclic plastic zone size.

The influence of strain rate across three orders of magnitude (1.70 × 10−5/s to 1.43 × 10−2/s) along with the effect of the plastic strain accumulation (up to 10%) on the serrated plastic flow were investigated in the nickel-chromium (Ni-Cr) solid solution alloy Nimonic 75 by performing constant-strain-rate tension testing at 600 °C. As the strain rate decreased, the critical strain for the onset of serrations transitioned from normal behavior to inverse behavior. The serrated flow was characterized as Type A+B serration at high strain rate (1.43 × 10−2/s). In the intermediate strain-rate regime (1.43 × 10−3/s and 1.45 × 10−4/s), Type B serrations were observed and followed by a transformation to Type C+B serrations. At the low strain rate (1.70 × 10−5/s), the plastic flow immediately displayed Type C serrations, which later evolved into Type C+B serrations. Regardless of the strain rate, plastic strain, or dislocation density, a critical dislocation velocity falling in the range of 1.2 × 10−6 – 2.2 × 10−6 m/s was identified to signify the onset of Type C serration, whereby the mobile dislocations break free from the solute cloud for short bursts of deformation. Finally, a novel model by solute rearrangement across dislocation cores was used to understand how the critical dislocation velocity is quantitatively determined by the rate at which solute atoms are able to hop across the glide plane as a partial dislocation core moves through the lattice.

This study aims to assess the accuracy of various modelling methodologies in predicting creep-fatigue damage (dcf) and cycles-to-crack-initiation (Ni) of Alloy 617 at 850 °C and 950 °C. In the decoupled methodologies, four creep damage models were employed: (i) the time fraction (TF), (ii) ductility exhaustion (DE), (iii) stress-modified ductility exhaustion (SMDE), and (iv) strain-energy density (SED), to capture the creep damage (dc) contribution to the overall creep-fatigue damage (dcf), while fatigue damage (df) contribution was always calculated using the simple “average” approach. Furthermore, we employed Holmström's integrated ϕ model, which combines the dcf into a single parameter without a need of separate assessment of creep damage (dc) and fatigue damage (df). The results show that there is no significant difference between the integrated ϕ model and decoupled creep-fatigue methodologies when the creep damage models are calibrated to creep-fatigue (CF) data. However, it is shown that the accuracy of the creep-fatigue damage (dcf) predictions using the decoupled approach gets significantly worse when the creep damage models are calibrated against independent creep-rupture (CR) data. It is further shown that when using DE, SMDE, SED creep damage models, the dcf predictions are arranged by strain range, suggesting that these models are better at capturing strain range variations rather than temperature changes. Based on the obtained results it is recommended that any of the employed creep damage models are all suitable for coupling with the “average” fatigue damage model when capturing the creep-fatigue behaviour of Alloy 617, as long as the employed creep damage model is calibrated directly to the experimental creep-fatigue (CF) data.

Laser additive manufacturing of bulk metallic glass (BMG) provides an effective bypassing of the critical casting thickness constraints that limit the size of components that can be produced; however, open questions remain regarding the resulting mechanical properties. In this work, a Zr-based BMG known as AMZ4 with composition Zr59.3Cu28.8Nb1.5Al10.4 was printed using a laser powder bed fusion (LPBF) technique. Micro X-ray computed tomography results together with electron microscopy imaging revealed porous processing defects in LPBF produced AMZ4 that led to a loss in tensile strength. Fatigue crack growth studies revealed a fatigue threshold, ΔKth., of ∼1.33 MPa√m and a Paris law exponent of m = 1.14, which are relatively low values for metallic materials. A KIC fracture toughness of 24−29 MPa√m was found for the LPBF BMG samples, which is much lower than the KQ of 97−138 MPa√m and KJIC of 158−253 MPa√m measured for the cast alloy with the same composition. The lower fracture toughness of the laser processed AMZ4 was attributed to ∼7.5× higher dissolved oxygen in the structure when compared to the cast AMZ4. Despite the higher level of oxygen, the formation of oxide nanocrystals was not observed by transmission electron microscopy. Oxygen induced toughness loss was confirmed by dissolving elevated concentrations of oxygen into cast AMZ4 rods, which led to a reduction in bending ductility and changes in the short-range order of the glass structure, as revealed by synchrotron X-ray diffraction.

Electrochemical water splitting offers an attractive approach for hydrogen production. However, the lack of high-performance cost-effective electrocatalyst severely hinders its applications. Here, a multinary high-entropy intermetallic (HEI) that possesses an unusual periodically ordered structure containing multiple non-noble elements is reported, which can serve as a highly efficient electrocatalyst for hydrogen evolution. This HEI exhibits excellent activities in alkalinity with an overpotential of 88.2 mV at a current density of 10 mA cm−2 and a Tafel slope of 40.1 mV dec−1, which are comparable to those of noble catalysts. Theoretical calculations reveal that the chemical complexity and surprising atomic configurations provide a strong synergistic function to alter the electronic structure. Furthermore, the unique L12-type ordered structure enables a specific site-isolation effect to further stabilize the H2O/H* adsorption/desorption, which dramatically optimizes the energy barrier of hydrogen evolution. Such an HEI strategy uncovers a new paradigm to develop novel electrocatalyst with superior reaction activities.

In this study, a machine-learning approach based on Gaussian process regression was developed to identify the optimized processing window for laser powder bed fusion (LPBF). Using this method, we found a new and much larger optimized LPBF processing window than was known before for manufacturing fully dense AlSi10Mg samples (i.e., relative density ≥ 99%). The newly determined optimized processing parameters (e.g., laser power and scan speed) made it possible to achieve previously unattainable combinations of high strength and ductility. The results showed that although the AlSi10Mg specimens exhibited similar Al-Si eutectic microstructures (e.g., cell structures in fine and coarse grains), they displayed large difference in their mechanical properties including hardness (118 - 137 HV 10), ultimate tensile strength (297 - 389 MPa), elongation to failure (6.3 - 10.3%), and fracture toughness (9.9 - 12.7 kJ/m2). The underlying reason was attributed to the subtle microstructural differences that were further revealed using two newly defined morphology indices (i.e., dimensional-scale index Id and shape index Is) based on several key microstructural features obtained from scanning electron microscopy images. It was found that in addition to grain structure, the sub-grain cell size and cell boundary morphology of the LPBF fabricated AlSi10Mg also strongly affected the mechanical properties of the material. The method established in this study can be readily applied to the LPBF process optimization and mechanical properties manipulation of other widely used metals and alloys or newly designed materials.

Porous Fe3O4 scaffolds were fabricated while subject to a low (7.8 mT) magnetic field applied in helical and Bouligand motions using a custom-built tri-axial nested Helmholtz coils-based freeze-casting setup. This setup allowed for the control of a dynamic, uniform low-strength magnetic field to align particles during the freezing process, resulting in the majority of lamellar walls aligning within ± 30° of the magnetic field direction and a decrease in porosity by up to 42%. Similar to how helical and Bouligand structures in nature promote impact resistance, these magnetic field motions produced structures with improved high strain rate mechanical properties. Strain at failure was increased by up to 2 times as cracks deflected to match the applied angles of rotation of the magnetic field.

Shape-memory materials (SMMs) are characterized by their unique ability to remember and recover their shape in response to external stimuli. Over recent decades, the use of SMMs in biomedical areas such as tissue engineering, drug delivery, endovascular surgery, orthodontics, orthopedics, etc. has attracted significant attention from both academia and industry. Recently, additive manufacturing (AM) has also attracted growing interest for biomedical applications because of its ability to produce on-demand, patient-tailored devices for medical treatments. This article provides a review of current state-of-the-art AM techniques for producing SMMs for biomedical applications. First, both shape-memory alloys and shape-memory polymers are discussed regarding their fundamental characteristics and compositions, and the general principles governing their shape-memory effects. Next, current and potential biomedical applications of SMMs are presented, then available AM techniques that have been used for the fabrication of SMM-based medical devices are discussed and explored. Finally, an outlook on AM of SMMs for biomedical applications is provided.

Objectives: Understand how discontinuous short glass fibers and braided long fibers can be effectively used to reinforce a resin modified glass ionomer cement (RMGIC) for carious lesion restorations. Methods: Two control groups (powder/liquid kit and capsule) were prepared from a light cured RMGIC. Either discontinuous short glass fibers or braided polyethylene fiber ribbons were used as a reinforcement both with and without pre-impregnation with resin. For the former case, the matrix was the powder/liquid kit RMGIC, and for the latter case the matrix was the capsule form. Flexural strength was evaluated by three-point beam bending and fracture toughness was evaluated by the single-edge V-notch beam method. Compressive strength tests were performed on cylindrical samples. Results were compared by analysis of variances and Tukey's post-hoc test. Flexural strength data were analyzed using Weibull statistical analysis. Results: The short fiber reinforced RMGIC both with and without pre-impregnation showed a significant increase of ∼50% in the mean flexural strength and 160–220% higher fracture toughness compared with the powder/liquid RMGIC control. Reinforcement with continuous braided fibers gave more than a 150% increase in flexural strength, and pre-impregnation of the braided fibers with resin resulted in a significant flexural strength increase of more than 300% relative to the capsule control. However, for the short fiber reinforced RMGIC there was no significant benefit of resin pre-impregnation of the fibers. The Weibull modulus for the flexural strength approximately doubled for the fiber reinforced groups compared to the control groups. Finally, compressive strength was similar for all the groups tested. Significance: By using a RMGIC as a matrix, higher flexural strength was achieved compared to reported values for short fiber reinforced GICs. Additionally, the short fibers provided effective toughening of the RMGIC matrix by a fiber bridging mechanism. Fin

Metallic glasses (MGs) with superior catalytic performance have recently been recognized as attractive candidates for wastewater treatment. However, further improving their performance will require knowledge of how to precisely regulate their electronic structures via compositional control. Here, two Fe-based MGs (Fe78Si9B13 and Fe80Si9B11) were prepared to compare how slightly altering boron content affected their electronic structure and catalytic performance. Density functional theory revealed that the Fe78Si9B13 MG with 2 atom % higher boron exhibits an attractive electron delocalization, a high persulfate adsorption energy, and a superb work function due to precise regulation of the electronic structure, leading to exceptional degradation performance for seven organic pollutants. Furthermore, it can be reused 23 times without significant deterioration of catalytic performance, amorphous structure, and surface morphology. This work provides a new paradigm for the fundamental theory explaining how electronic structure is controlled by composition, creating a solid foundation to explore novel catalysts for water treatment.

In order to understand the fracture toughness anisotropy of avian eggshells, we have investigated eggshells of the emu (Dromaius novaehollandiae) whereby the large size (~13 cm × 9.5 cm) enabled the fabrication of beam samples in various orientations. The emu eggshell was found to have a hierarchical microstructure similar to chicken eggshell, with the only significant difference being the absence of a continuous cuticle layer. Emu eggshell was found to have significantly lower strength when samples were tested in the outwards direction (i.e., a crack initiates on the inside of the shell and propagates towards the outer surface) as compared to the inwards testing direction. Furthermore, samples that were oriented parallel to the egg axis (i.e., the longitudinal direction) and tested inwards showed higher strength, ~24 MPa, compared to the samples that were made from the latitudinal orientation, ~20 MPa. Independent of orientation, the outwards testing direction resulted in strength values of ~15 MPa. The fracture toughness of the emu eggshell for cracking in the circumferential direction was ~0.3 MPa√m, independent of sample orientation, and this value was comparable to the fracture toughness of chicken eggshell tested in the same orientation. In the radial outwards direction, however, the fracture toughness was ~80% lower (~0.06 MPa√m) than in the circumferential direction. The low fracture toughness for this orientation was associated with the separation of the highly oriented calcite crystals in the mammillary cone layer of the eggshell structure which is easier compared to calcite crystal fracture. The large anisotropy in fracture toughness is thought to allow for easy escape of the chick while simultaneously protecting the embryo during development.

Shear bands were introduced into a Zr–Ti–Cu–Ni–Al bulk metallic glass (BMG) by one-directional cold rolling and the effect on fracture toughness anisotropy was examined. Two different rolling and shear band orientations relative to the crack plane were used, with the rolling force oriented along either the width (CR-W) or thickness (CR-T) direction of single edge notched bend specimens. The results showed the CR-W samples demonstrated a 50% reduction in KQ relative to the as-cast material while the CR-T samples demonstrated the highest fracture toughness. The low fracture toughness of the CR-W samples was attributed to easy crack propagation paths formed by the shear bands. In contrast, the higher fracture toughness of the CR-T samples was attributed to the difficulty of crack twisting out of the mode I precrack plane onto the shear band planes and the high energy absorption of mode III tearing between the parallel crack planes. Overall, when cold rolling BMGs for structural applications, care must be taken to design the shear band morphologies to achieve the desired fracture toughness properties rather than solely focusing on increasing the average relaxation enthalpy/free volume.

Background: To close elliptical excisions, surgeons commonly use the rule of halves which involves initially closing of the middle portion of the wound, followed by closure of the remaining halves. Understanding the forces required for suturing such wounds can aid excisional surgery planning to decrease complications and improve wound healing. Methods: Following full thickness excision for removal of skin cancers, back wounds with 3:1 ratio of length-to-width were closed using the rule of halves. The force required to bring the wound edges into contact at the middle portion of the wound was measured, followed by the two bisected halves. Findings: The average force to close the center of the wounds averaged 3.7 N and was six times larger than that of the bisected halves. The forces to close the bisected halves were consistently small, and essentially negligible (<0.5 N) for ~50% of the cases. Interpretation: When planning excisional surgery to avoid complications such as tearing the dermis (cheese wiring), the use of special wound closure techniques (high tension and/or pully sutures, skin support or suture retention devices, etc.) should focus on the center suture only when using the rule of halves, as the remaining sutures require very low forces.

Objectives: Diet-induced metabolic dysfunction such as type 2 diabetes mellitus increases the risk of implant failure in both dental and orthopaedic settings. We hypothesised that a diet high in fat and fructose would adversely affect peri-implant bone structure and function including osseointegration. Materials and methods: Thirty female Sprague-Dawley rats were divided into three groups (n = 10), control group (normal chow) and two intervention groups on a high-fat (60%), high-fructose (20%; HFHF) diet. Titanium implants were placed in the proximal tibial metaphysis in all groups either before commencing the diet (dHFHF group) or 6 weeks after commencing the diet (HFHF group) and observed for an 8-week healing period. Fasting blood glucose levels (fBGLs) were measured weekly. Structural and functional features of the peri-implant bone, including bone-to-implant contact (BIC), were analysed post euthanasia using microcomputed tomography, pull-out tests, and dynamic histomorphometry. Results: The fBGLs were unchanged across all groups. Peri-implant trabecular bone volume was reduced in the HFHF group compared with controls (p =.02). Percentage BIC was reduced in both HFHF group (25.42 ± 3.61) and dHFHF group (28.56 ± 4.07) compared with the control group (43.26 ± 3.58, p <.05) and reflected the lower pull-out loads required in those groups. Osteoblast activity was reduced in both intervention groups compared with the control group (p <.05). Conclusion: The HFHF diet compromised osseointegration regardless of whether the implant was placed before or after the onset of the diet and, despite the absence of elevated fBGLs, confirming that changes in bone cell function affected both the initiation and maintenance of osseointegration independent of blood glucose levels.

The incorporation of antimicrobial agents in restorative dental composites has the potential to slow the development of carious lesions. Objective: The objectives of the present study were to develop experimental composite resins with chitosan or chitosan loaded with dibasic calcium phosphate anhydrous (DCPA) particles and to demonstrate their antimicrobial potential without loss of mechanical properties or biocompatibility. Methods: Chitosan and chitosan/DCPA particles were synthetized by the electrospray method. Experimental composites were formulated by adding 0, 0.5, or 1.0 wt% particles into a resin matrix along with 60 wt% barium glass. The degree of conversion and mechanical properties were measured after 1 and 90 days of aging in water after photoactivation. Cytotoxicity and genotoxicity were evaluated using fibroblasts from dental pulp in conditioned medium. The antimicrobial activity against Streptococcus mutans was assessed by crystal violet biofilm assay. Results: The experimental restorative composites were not found to be cytotoxic or genotoxic, with cell viability of 93.1 ± 8.0% (p = 0.328) and 3.0 ± 0.8% micronucleus per group (p = 0.1078), respectively. The antimicrobial results showed that all composites with approximately 20% less biofilm (p < 0.001) relative to the control. No chitosan release was detected from the composites, suggesting direct contact of the bacteria with exposed chitosan particles on the surface was responsible for the observed antimicrobial effect. The addition of the chitosan and chitosan/DCPA submicrometer (<250 nm average diameter) particles to restorative composites did not change the degree of conversion, flexural strength, elastic modulus and fracture toughness compared to the control group after 90 days aging in water. Significance: It can be concluded that the addition of chitosan or chitosan/DCPA particles in the restorative composites induced antimicrobial activity without compromising the mechanical properties or bi

© 2019 The molten salt corrosion performance of a Ni–Mo–Cr (GH3535) alloy weldment, produced using matching filler metal, was assessed. Corrosion testing was performed in FLiNaK molten salt at 750 °C for 500 h. Present results reveal that, despite a similar chemical composition, the weld metal has somewhat superior corrosion resistance to the parent metal. The difference is primarily attributed to the significantly lower density of high-angle grain boundaries (HAGBs) in the weld metal. Results further suggest that large M6C carbides present in the parent metal may contribute to corrosion attack of the alloy matrix via galvanic corrosion.

An irreversible cohesive zone model was used to understand how plastic strain gradients and yield strength mismatches affect fatigue crack growth across bi-material and multilayer interfaces for a range of interface strengths. Parametric studies identified regimes of penetration through the interface, deflection into the interface, and a transition where cracks extend on both paths. Plastic strain gradients strongly influence the transition regime, and a yield strength mismatch is necessary to cause deflection. For crack growth across an interlayer, interactions between the interfaces occur when the crack-tip plastic zone spans the interlayer. Plastic strain gradients promote penetration through the interlayer.

Some natural materials, such as the dactyl club of the mantis shrimp, have impressive mechanical properties (e.g. strength) due to their microstructure that consists of periodic layers of high and low density material, which prevent crack propagation. Although such layered structures have the potential to increase the strength of engineered epoxy-ceramic composites relative to their constituents, synthetically replicating this class of layered structures in engineered materials has been challenging to date. To overcome this challenge, ultrasound freeze casting (UFC) was used to manufacture macroscale specimens of epoxy-ceramic composite materials with periodic layers of high and low density that mimic the structure of natural materials. The critical operating parameter of the UFC technique, the ultrasound operating frequency, was related to the resulting hardness, porosity, and flexural strength of the resultant epoxy-ceramic composite materials. Scanning electron microscopy and micro X-ray CT was used to visualize the microstructure of the specimens and connect it to the mechanical properties. The ultrasound operating frequency controlled the spacing of the layers as well as the local hardness of the epoxy-ceramic composite, which increased by up to 18%. The flexural strength of the epoxy-ceramic composite was also related to the ultrasound operating frequency, with a maximum increase of 52%.

Fe-based metallic glasses have been confirmed to degrade azo dyes effectively, however, a detailed understanding, of the role of alloying elements and crystallization is still elusive. Herein, it is reported that boron-facilitated hybrid structures greatly improve the degradation of methyl orange (MO) and the degrading rate can be further improved by 2.5 times after fully crystallization. Three distinct types of galvanic cells created by different iron-containing phases are believed to dominate the degradation reactions. Most notably, some FeB-based compounds precipitated from FeB-based metallic glasses, such as Fe2B, FeB and Fe5SiB2, are found to have more negative electrode potential and higher catalytic efficiency than iron. These compounds create galvanic cells with α-Fe and lose electrons, therefore promoting the degradation reaction. The favorable effects of the FeB-based compounds are discussed at the light of their electron densities and energy band structures. These findings open a new research strategy to developing iron-bearing catalysts for improved degradation of azo dyes.

Refractory high-entropy alloys (RHEAs) are potential candidate materials for use in next-generation nuclear reactors due to their excellent mechanical performance at high temperatures. Here, we investigate the microstructure and mechanical properties of the nanocrystalline RHEA TiZrNbHfTa before and after irradiation with He2+ ions to determine radiation-induced property changes. Using nanoindentation and in situ microtensile testing we find only small changes in hardness after irradiation but a significant increase in yield and ultimate tensile strength without loss in ductility. This is associated with radiation hardening and a shift from shear localization failure with smooth fracture surfaces to a fracture morphology consisting of fine dimples and intergranular failure characteristics. Overall, the material shows excellent damage-tolerant properties with good combinations of strength and ductility both prior to and after ion irradiation.

Although metallic glasses (MGs) with unique disordered atomic structure have increasingly attracted great research interest as one of the most innovative heterogeneous catalysts in water remediation, few works focused on the synergistic role of different elemental constituents to well understand their superb catalytic performance. Herein, Co atoms were selected to partially substitute for the Fe elements in Fe-based MGs to study the corresponding synergistic catalytic function in dye degradation. Experimental results demonstrated that the Fe36Co36Si4.8B19.2Nb4 MG with a kinetic rate constant of k = 0.06 min−1 degrades rhodamine B (RhB) dye 20 times faster than the Fe73.5Si13.5B9Cu1Nb3 MGs with k = 0.003 min−1. Three types of dye including RhB, methylene blue (MB) and malachite green were investigated to draw attention to the broad, practical applications. Various chemical parameters, such as catalyst dosage, persulfate concentration, and dye concentration, were also studied. Quenching experiments indicated that the highly active hydroxyl (⋅OH) and sulfate (SO4⋅−) radicals are largely produced from persulfate by the activation of the Fe36Co36Si4.8B19.2Nb4 MG catalyst. This critical work uncovers a new paradigm to establish an effective approach for alloy design in widespread catalytic applications.

A Zr-based bulk metallic glass produced using selective laser melting (SLM) was compared to the same alloy fabricated using traditional suction-casting. Analysis of the fracture toughness through single edge notched beam bending experiments showed a significantly reduced damage tolerance for the laser-processed material (KQ ~ 138.0 ± 13.1 → 28.7 ± 3.7 MPa √m), even though X-ray diffraction and microhardness responses were identical. Using uniaxial quasistatic micro-pillar compression, it was found that as-cast samples more readily underwent shear transformations (evidenced through discrete load drops) below the nominal 0.2% yield stress, which was connected to the higher macroscopic toughness. Differential scanning calorimetry demonstrated that the increased barrier to shear transformation for the SLM material could not be explained by the relative relaxation states. Rather, it was attributed to the greater dissolved oxygen concentration in the laser-processed material, which is postulated to decrease atomic mobility in the structure and thereby increase the activation energy required to initiate shear transformations.

The authors regret that the caption for Figure 5 is incorrect, and should read as follows: Fig. 5. The transition from transgranular cracking to a mixed transgranular-intergranular cracking mechanism for 0.05 Hz samples cycled with R = 0.5 as ΔK was increased from 7.6 to 15.9 MPa√m. Data for 5 and 0.33 Hz are grouped in black, and data for 0.05 Hz triangle and trapezoid (1.5s-17s–1.5s) waveforms are grouped in gray. Circles on the plot indicate where each micrograph is located on the crack growth rate curve, and each micrograph is scaled identically. The authors would like to apologise for any inconvenience caused.

This study aims to predict the creep response of Alloy 617 and assess the accuracy of three established creep damage models in predicting the creep time-to-failure (tf) and strain-to-failure (εf) in the temperature range of 800–1000 °C. Idaho National Laboratory (INL) creep data were used to calibrate (1) Ductility Exhaustion (DE), (2) Stress-Modified Ductility Exhaustion (SMDE), and (3) Strain-Energy Density (SED) creep damage models using multiple linear regression (LR) and reverse damage (RD) approaches. In order to predict the creep response of Alloy 617 these creep damage models are then coupled with (secondary) creep strain model calibrated using Idaho National Laboratory (INL), Korean Atomic Energy Research Institute (KAERI), and Argonne National Laboratory (ANL) experimental data. Direct comparisons made between the investigated creep damage models revealed that the SED model with parameters calibrated through RD approach captures the creep response of Alloy 617 the most accurately and it thus produces the most accurate prediction of time-to-failure (tf) and strain-to-failure (εf) across different temperature/stress (creep) conditions. However, it is also shown that none of the employed creep damage models are able to fully capture the material creep response at 1000 °C. This is attributed the strong oxidation of Alloy 617 at 1000 °C (tested in air) leading to the formation of a thick oxidation layer, which might affect the failure mechanism of the alloy at this temperature.

Additive manufacturing of bulk metallic glasses (BMGs) allows for effective bypassing of critical casting thickness constraints for glassy alloys, opening up this exciting material class to new applications. An open question is how the laser processing of such materials affects the short-range structural order, a critical mediating parameter for glass deformation. Synchrotron X-ray microdiffraction was used to understand structural heterogeneity across the build-planes of a selective laser melted Zr-based BMG. While negligible macroscopic heterogeneity in the structure was observed over a 10 mm build height for the X-ray amorphous material, small periodic variations were observed on the order of 40-80 μm. This dimensional scale was rationalized as a consequence of melt-pool solidification from laser processing, which imparts a calculated local strain variation of ±0.1%. It is anticipated that this structural insight will help to rationalize microscale deformation effects from the periodic structural variation of selective laser melting produced BMGs.

Objectives: Understand how cooling protocols control the microstructure and mechanical properties of veneering porcelains. Methods: Two porcelain powders were selected, one used to veneer metallic frameworks (VM13) and one for zirconia frameworks (VM9). After the last firing cycle, the monolithic specimens were subjected to two cooling protocols: slow and fast. Flexural strength (FS) was evaluated by three-point beam bending and fracture toughness (KIC) was evaluated by the single-edge V-notch beam (SEVNB) method. Scanning electron microscopy (SEM) was performed to determine the leucite crystal volume fraction (%), particle size, and matrix microcrack density. The results were compared by analysis of variances (ANOVA) and Tukey's multiple comparison test. Results: The mechanical properties were significantly (p < 0.05) higher for the VM13 porcelain (FS = 111.0 MPa, KIC = 1.01 MPa.√m) compared to VM9 (FS = 79.6 MPa, KIC =0.87 MPa.√m) regardless of cooling protocol due to ∼250% higher volume fraction of leucite crystals. The slow cooled VM13 and fast cooled VM9 resulted in the highest and lowest mechanical properties, respectively, while the VM9 slow cooled properties were similar to the VM13 fast cooled. The SEM revealed that the slow cooling significantly increased the volume fraction of leucite crystals by 33–41 %. Across both porcelains, a significant linear correlation between both mechanical properties (strength and toughness) and leucite crystal content was found. Slow cooling was also associated with increased crystal growth resulting in more matrix microcracking. Significance: Controlled crystallization using slow cooling can be applied as a means of strengthening dental porcelains. However, the benefits of slow cooling may be partially offset by increasing the microcrack density in the glass matrix. To achieve the maximum benefit of slow cooling, it is recommending to develop heat treatments to produce porcelain with fine-grained and homogenously dispersed l

Driven by the need to reduce CO2 emissions from fossil power generation, new turbine working fluids are being investigated. One such fluid, supercritical carbon dioxide (sCO2), offers potential for improved energy conversion efficiency. In situ corrosion studies on precipitate-hardened nickel superalloys in sCO2 have shown potentially dangerous subsurface depletion of gamma prime phase. In the present work, the ex situ effect of supercritical fluid exposure on fatigue crack growth thresholds was measured for the Ni-based superalloy Haynes 282. After exposure of 500 h at 730 °C, there was a small measurable and repeatable reduction in fatigue thresholds at room temperature from 13 to 11 MPa√m after exposure. This reduction in fatigue crack growth threshold occurred irrespective of the exposure environment and was attributed to a decrease in roughness-induced crack closure.

Objective: Conduct a first in vivo study on the large deformation stress relaxation behavior of the human scalp. Methods: This study was conducted during Mohs micrographic surgery of the scalp of 14 patients aged 59–90 with wounds initially ranging from 9 to 41 mm wide. The initial wound diameter was measured under zero applied force. Then, the force required to close each wound using a single size 1 nylon suture and a SUTUREGARD suture retention device was measured, after which the suture was then locked in the retention device at fixed displacement. At time points of 300 s, 600 s, and 1800 s, the suture retention device was released, and the wound opening was again recorded at zero force, and the force required to close the wound was recorded. Results: The average wound closure force relaxed by 44% and 65% after 300 s and 1800 s, respectively. Average wound width decreased 30% and 42%, after 300 s and 1800 s, respectively, due to creep deformation. Furthermore, all wounds relaxed to be below 15 N of closure force after 600 s, which is considered the maximum clinically acceptable force. A relaxation time of ∼270 s and a threshold force for creep of ∼5 N was found. Significance: Results of this study provide the first quantitative clinical guidance for efficient scalp closure of large wounds by creep deformation and stress relaxation. Furthermore, the methodology developed here can be used as a basis for future in vivo studies of the stress relaxation and creep deformation of human scalp, which in turn can provide data for the development and validation of constitutive models for scalp deformation.

In this work, temperature dependent mechanical properties of conventional and additive manufactured Inconel 718 (IN718) after solution and aging (SA) heat treatment were measured at room temperature, 350 °C, and 650 °C. Nanoindentation technique was used to obtain material properties including hardness, reduced modulus, creep rate, creep stress exponent, and thermal activation volume. The indentation size effect (ISE) was analyzed at each temperature. The reduced modulus was measured to decrease by 26% for the conventional samples and by 22% for AM samples as temperature increases from room temperature to 650 °C. The nanoindentation hardness decreases by 19% for the conventional samples and 16% for the AM samples. During the creep tests at 650 °C, the creep stress exponent was found in the range of 8-18, indicating that the deformation at the examined nano/micro scale is controlled by the dislocation climb mechanism.

In this study, as-cast and cold-rolled Zr63.78Cu14.72Ni10Al10Nb1.5 bulk metallic glass (BMG) samples were subjected to 20, 70, 120, and 170 cryogenic thermal cycles prior to fracture toughness testing. Thermal cycling raised the fracture toughness by promoting plastic deformation and stable crack growth, with the most significant increase occurring after the first 20 thermal cycles. Thermally cycled samples showed more tortuous crack paths and stable crack propagation left periodic blunting marks spaced at ∼57.5 μm on the fracture surface corresponding to each increment of crack advance. Microhardness mapping revealed a microstructure of hard and soft domains (∼63 μm × 105 μm), and thermal cycling heterogeneously softened the hard domains while the soft domains remained apparently unchanged. In addition to the observed softening, large increases in the relaxation enthalpy, and thus the average free volume, were found over the first ∼70 thermal cycles. While cold rolling the samples prior to the thermal cycling did not raise the mean fracture toughness values, the scatter was reduced compared to as-cast thermal cycled samples. This was attributed to the introduction of shear bands giving a more repeatable initial microstructure than casting.

Fatigue crack growth is analyzed for steady state and overload conditions. The model combines an elastic-plastic strain gradient hardening material and an irreversible cohesive zone model. Plastic strain gradients are found not to affect steady-state fatigue crack growth but play a key role in the overload response. Plastic strain gradient hardening lowers plastic strain magnitudes and alters the spatial distribution of plastic strain. This leads to reduced crack closure and higher crack growth rates during and after the overload. Using classical plasticity alone to describe fatigue crack growth following an overload is thus nonconservative.

OBJECTIVES: Diet-induced metabolic dysfunction such as type 2 diabetes mellitus increases the risk of implant failure in both dental and orthopaedic settings. We hypothesised that a diet high in fat and fructose would adversely affect peri-implant bone structure and function including osseointegration. MATERIALS AND METHODS: Thirty female Sprague-Dawley rats were divided into three groups (n = 10), control group (normal chow) and two intervention groups on a high-fat (60%), high-fructose (20%; HFHF) diet. Titanium implants were placed in the proximal tibial metaphysis in all groups either before commencing the diet (dHFHF group) or 6 weeks after commencing the diet (HFHF group) and observed for an 8-week healing period. Fasting blood glucose levels (fBGLs) were measured weekly. Structural and functional features of the peri-implant bone, including bone-to-implant contact (BIC), were analysed post euthanasia using microcomputed tomography, pull-out tests, and dynamic histomorphometry. RESULTS: The fBGLs were unchanged across all groups. Peri-implant trabecular bone volume was reduced in the HFHF group compared with controls (p = .02). Percentage BIC was reduced in both HFHF group (25.42 ± 3.61) and dHFHF group (28.56 ± 4.07) compared with the control group (43.26 ± 3.58, p < .05) and reflected the lower pull-out loads required in those groups. Osteoblast activity was reduced in both intervention groups compared with the control group (p < .05). CONCLUSION: The HFHF diet compromised osseointegration regardless of whether the implant was placed before or after the onset of the diet and, despite the absence of elevated fBGLs, confirming that changes in bone cell function affected both the initiation and maintenance of osseointegration independent of blood glucose levels.