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1. Serum biomarker panel diagnostics in pancreatic ductal adenocarcinoma: the clinical utility of soluble interleukins, IFN-γ, TNF-α and PD-1/PD-L1 in comparison to established serum tumor markers

Author

Dorman, Klara, Gerckens, Miriam, Kruger, Stephan, Krueger, Kimberly, Mayer, Zsuzsanna, Rupp, Alexander, Zhang, Danmei, Weiss, Lena, Westphalen, C. Benedikt, Haas, Michael, Guenther, Michael, Ormanns, Steffen, Klawonn, Frank, Werner, Jens, von Bergwelt-Baildon, Michael, Heinemann, Volker, Boeck, Stefan, and Holdenrieder, Stefan

Published
2023
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2. T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours

Author

Lesch, Stefanie, Blumenberg, Viktoria, Stoiber, Stefan, Gottschlich, Adrian, Ogonek, Justyna, Cadilha, Bruno L., Dantes, Zahra, Rataj, Felicitas, Dorman, Klara, Lutz, Johannes, Karches, Clara H., Heise, Constanze, Kurzay, Mathias, Larimer, Benjamin M., Grassmann, Simon, Rapp, Moritz, Nottebrock, Alessia, Kruger, Stephan, Tokarew, Nicholas, Metzger, Philipp, Hoerth, Christine, Benmebarek, Mohamed-Reda, Dhoqina, Dario, Grünmeier, Ruth, Seifert, Matthias, Oener, Arman, Umut, Öykü, Joaquina, Sandy, Vimeux, Lene, Tran, Thi, Hank, Thomas, Baba, Taisuke, Huynh, Duc, Megens, Remco T. A., Janssen, Klaus-Peter, Jastroch, Martin, Lamp, Daniel, Ruehland, Svenja, Di Pilato, Mauro, Pruessmann, Jasper N., Thomas, Moritz, Marr, Carsten, Ormanns, Steffen, Reischer, Anna, Hristov, Michael, Tartour, Eric, Donnadieu, Emmanuel, Rothenfusser, Simon, Duewell, Peter, König, Lars M., Schnurr, Max, Subklewe, Marion, Liss, Andrew S., Halama, Niels, Reichert, Maximilian, Mempel, Thorsten R., Endres, Stefan, and Kobold, Sebastian

Published
2021
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3. Neoadjuvant therapy in elderly patients receiving FOLFIRINOX or gemcitabine/nab-paclitaxel for borderline resectable or locally advanced pancreatic cancer is feasible and lead to a similar oncological outcome compared to non-aged patients – Results of the RESPECT-Study

Author

Schmid, Daniel, D'Haese, Jan G., Böck, Stephan, Kruger, Stephan, Haas, Michael, Röder, Falk, Chiaro, Marco del, Löhr, Matthias, Tamburrino, Domenico, Masini, Gaia, Maisonneuve, Patrick, Malleo, Giuseppe, Salvia, Roberto, Charnley, Richard, Weniger, Maximilian, Moir, John, Damm, Marko, Maggino, Laura, Kordes, Maximilian, Rosendahl, Jonas, Ceyhan, Güralp O., and Schorn, Stephan

Published
2020
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4. Respect - A multicenter retrospective study on preoperative chemotherapy in locally advanced and borderline resectable pancreatic cancer

Author

Schmid, Daniel, D'Haese, Jan G., Werner, Jens, Boeck, Stefan, Kruger, Stephan, Haas, Michael, Roeder, Falk, Friess, Helmut, Chiaro, Marco del, Löhr, Matthias, Tamburrino, Domenico, Falconi, Massimo, Masini, Gaia, Maisonneuve, Patrick, Malleo, Giuseppe, Salvia, Roberto, Bassi, Claudio, Charnley, Richard, Algül, Hana, Schmidt, Melissa, Lange, Sebastian, Michl, Patrick, Weniger, Maximilian, Moir, John, Damm, Marko, Maggino, Laura, Kordes, Maximilian, Rosendahl, Jonas, Ceyhan, Güralp O., and Schorn, Stephan

Published
2020
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6. Prolonged time to treatment initiation in advanced pancreatic cancer patients has no major effect on treatment outcome: a retrospective cohort study controlled for lead time bias and waiting time paradox

Author

Kruger, Stephan, Schirle, Karoline, Haas, Michael, Crispin, Alexander, Schirra, Jörg, Mayerle, Julia, D’Haese, Jan G., Kunz, Wolfgang G., Ricke, Jens, Ormanns, Steffen, Kirchner, Thomas, Kobold, Sebastian, Ilmer, Matthias, Gebauer, Leonie, Westphalen, Christoph B., von Bergwelt-Baildon, Michael, Werner, Jens, Heinemann, Volker, and Boeck, Stefan

Published
2020
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7. Contributors

Author

Ahmed, Mahmoud Salama, primary, Angele, Martin K., additional, Attia, Yasmeen M., additional, Basso, João, additional, Bouche, Gauthier, additional, Chakraborti, Sohini, additional, Chakravarthi, Pushpaveni, additional, Chang, Hsuen-Wen Kate, additional, Chang, Vincent H.S., additional, Cheng, Bei, additional, Cho, William C.S., additional, D'Haese, Jan G., additional, Dou, Q. Ping, additional, Efferth, Thomas, additional, Ewida, Heba, additional, Fortuna, Ana, additional, GNS, HemaSree, additional, Hernández-Lemus, Enrique, additional, Huang, Yingbo, additional, Huang, R. Stephanie, additional, Ilmer, Matthias, additional, Khan, Harras J., additional, Krishna Murthy, Mamatha, additional, Kruger, Stephan, additional, Lim, Hansaim, additional, Mariam Jos, Swarna, additional, Meheus, Lydie, additional, Mendes, Maria, additional, Nath, Aritro, additional, Niess, Hanno, additional, Ölgen, Süreyya, additional, Othman Ahmed, Zainab Sabry, additional, Pai, Rachana R, additional, Pais, Alberto, additional, Pantziarka, Pan, additional, Pareek, Siddhika, additional, PrasannaMarise, V Lakshmi, additional, Renz, Bernhard W., additional, Rohondia, Sagar O., additional, Rombauts, Klara, additional, Saraswathy, Ganesan Rajalekshmi, additional, Sousa, João, additional, Srinivasan, Narayanaswamy, additional, To, Kenneth K.W., additional, Vandeborne, Liese, additional, Vitorino, Rui, additional, Vitorino, Carla, additional, Weniger, Maximilian, additional, Werner, Jens, additional, Westphalen, C. Benedikt, additional, Wu, Yang, additional, Xie, Lei, additional, Xu, Peisheng, additional, Yan, Ge, additional, Zalavadiya, Nirav, additional, and Zhang, Chun, additional

Published
2021
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9. Immune Cell and Stromal Signature Associated With Progression-Free Survival of Patients With Resected Pancreatic Ductal Adenocarcinoma

Author

Mahajan, Ujjwal Mukund, Langhoff, Eno, Goni, Elisabetta, Costello, Eithne, Greenhalf, William, Halloran, Christopher, Ormanns, Steffen, Kruger, Stephan, Boeck, Stefan, Ribback, Silvia, Beyer, Georg, Dombroswki, Frank, Weiss, Frank-Ulrich, Neoptolemos, John P., Werner, Jens, D’Haese, Jan G., Bazhin, Alexandr, Peterhansl, Julian, Pichlmeier, Svenja, Büchler, Markus W., Kleeff, Jörg, Ganeh, Paula, Sendler, Matthias, Palmer, Daniel H., Kohlmann, Thomas, Rad, Roland, Regel, Ivonne, Lerch, Markus M., and Mayerle, Julia

Published
2018
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15. Advances in cancer immunotherapy 2019 – latest trends

Author

Kruger, Stephan, Ilmer, Matthias, Kobold, Sebastian, Cadilha, Bruno L., Endres, Stefan, Ormanns, Steffen, Schuebbe, Gesa, Renz, Bernhard W., D’Haese, Jan G., Schloesser, Hans, Heinemann, Volker, Subklewe, Marion, Boeck, Stefan, Werner, Jens, and von Bergwelt-Baildon, Michael

Published
2019
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16. Clinical impact of structured post-operative surveillance in resected pancreatic adenocarcinoma: Results from a retrospective cohort study

Author

Zhang, Danmei, primary, Kruger, Stephan, additional, Schirle, Karoline, additional, Heinemann, Volker, additional, Dorman, Klara, additional, Westphalen, Benedikt, additional, Weiss, Lena, additional, Gebauer, Leonie, additional, Günther, Michael, additional, Ormanns, Steffen, additional, Werner, Jens, additional, von Bergwelt-Baildon, Michael, additional, Boeck, Stefan, additional, and Haas, Michael, additional

Published
2022
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19. Serum biomarker panel diagnostics in pancreatic ductal adenocarcinoma: the clinical utility of soluble interleukins, IFN-γ, TNF-α and PD-1/PD-L1 in comparison to established serum tumor markers

Author

Dorman, Klara, primary, Gerckens, Miriam, additional, Kruger, Stephan, additional, Krueger, Kimberly, additional, Mayer, Zsuzsanna, additional, Rupp, Alexander, additional, Zhang, Danmei, additional, Weiss, Lena, additional, Westphalen, C. Benedikt, additional, Haas, Michael, additional, Guenther, Michael, additional, Ormanns, Steffen, additional, Klawonn, Frank, additional, Werner, Jens, additional, von Bergwelt-Baildon, Michael, additional, Heinemann, Volker, additional, Boeck, Stefan, additional, and Holdenrieder, Stefan, additional

Published
2022
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20. Clinical Impact of Structured Post-Operative Surveillance in Resected Pancreatic Adenocarcinoma: Results from a Retrospective Cohort Study.

Author

Zhang, Danmei, Kruger, Stephan, Schirle, Karoline, Heinemann, Volker, Dorman, Klara, Westphalen, Christoph Benedikt, Weiss, Lena, Gebauer, Leonie, Günther, Michael, Ormanns, Steffen, Werner, Jens, von Bergwelt-Baildon, Michael, Boeck, Stefan, and Haas, Michael

Subjects
*ADENOCARCINOMA, *COHORT analysis, *PANCREATIC duct, *CLINICAL deterioration, *PROGRESSION-free survival, *PANCREATIC surgery, *PANCREATIC intraepithelial neoplasia
Abstract

Introduction: To this date, surgery remains the only potentially curative approach in the treatment of pancreatic cancer. To analyse the clinical impact of a structured post-operative follow-up programme, we retrospectively analysed a cohort of resected pancreatic adenocarcinoma patients treated at LMU Munich. Methods: Pancreatic adenocarcinoma patients who underwent resection and presented for regular follow-up visits at our centre between 2002 and 2017 were identified from two existing study cohorts. Diagnosis of recurrences was categorised by timing (within or outside a scheduled follow-up visit) and detection modality (imaging, CA 19-9 increase, or clinical deterioration) and correlated with disease-free survival and overall survival (OS). Results: One hundred and twenty-five patients with resected pancreatic adenocarcinoma were included in this analysis. Median OS in the whole cohort was 21.1 months. Of these 125 patients, 103 (82.4%) patients had a documented relapse. Tumour recurrences detected within a scheduled follow-up visit (n = 86, 83.5%) compared to recurrences becoming apparent at an unplanned visit (n = 17, 16.5%) were associated with a significantly improved OS (median 25.5 vs. 20.2 months, p = 0.019). Compared to patients with recurrence detected by clinical deterioration (n = 4, 3.9%), patients with recurrences detected by imaging or laboratory abnormalities (n = 99, 96.0%) had a longer median OS (24.8 vs. 15.1 months, p = 0.007). Discussion: A structured follow-up after pancreatic ductal adenocarcinoma resection may have an impact on patient outcome. Prospective trials are needed to evaluate the clinical impact of post-operative follow-up programmes. [ABSTRACT FROM AUTHOR]

Published
2023
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22. Quantitative Imaging Biomarkers of the Whole Liver Tumor Burden Improve Survival Prediction in Metastatic Pancreatic Cancer

Author

Gebauer, Leonie, primary, Moltz, Jan H., additional, Mühlberg, Alexander, additional, Holch, Julian W., additional, Huber, Thomas, additional, Enke, Johanna, additional, Jäger, Nils, additional, Haas, Michael, additional, Kruger, Stephan, additional, Boeck, Stefan, additional, Sühling, Michael, additional, Katzmann, Alexander, additional, Hahn, Horst, additional, Kunz, Wolfgang G., additional, Heinemann, Volker, additional, Nörenberg, Dominik, additional, and Maurus, Stefan, additional

Published
2021
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25. Impact of completeness of adjuvant gemcitabine, relapse pattern, and subsequent therapy on outcome of patients with resected pancreatic ductal adenocarcinoma – A pooled analysis of CONKO-001, CONKO-005, and CONKO-006 trials

Author

Kurreck, Annika, primary, Weckwerth, Johanna, additional, Modest, Dominik P., additional, Striefler, Jana K., additional, Bahra, Marcus, additional, Bischoff, Sven, additional, Pelzer, Uwe, additional, Oettle, Helmut, additional, Kruger, Stephan, additional, Riess, Hanno, additional, and Sinn, Marianne, additional

Published
2021
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28. Challenges in Clinical Trial Design for T Cell-Based Cancer Immunotherapy

Author

Kruger, Stephan F., Cadilha, Bruno L., von Bergwelt-Baildon, Michael, Endres, Stefan, Kobold, Sebastian, Kruger, Stephan F., Cadilha, Bruno L., von Bergwelt-Baildon, Michael, Endres, Stefan, and Kobold, Sebastian

Abstract

Chimeric antigen receptor T cells can induce impressive response rates in patients with refractory B cell malignancies. Adoptive transfer of tumor infiltrating lymphocytes or T cell receptor-engineered T cells are other promising treatment modalities currently in clinical development. Requirements for clinical trial design for T cell-based cancer immunotherapy significantly differ from established criteria for small-molecule or antibody-based anticancer drugs. Here, we highlight important differences regarding preclinical development, trial design, and reporting of clinical trials.

Published
2020

29. Cathepsin D Expression and Gemcitabine Resistance in Pancreatic Cancer

Author

Mahajan, Ujjwal M., Goni, Elisabetta, Langhoff, Enno, Li, Qi, Costello, Eithne, Greenhalf, William, Kruger, Stephan, Ormanns, Steffen, Halloran, Christopher, Ganeh, Paula, Marron, Manuela, Laemmerhirt, Felix, Zhao, Yue, Beyer, Georg, Weiss, Frank-Ulrich, Sendler, Matthias, Bruns, Christiane J., Kohlmann, Thomas, Kirchner, Thomas, Werner, Jens, D'Haese, Jan G., von Bergwelt, Michael, Heinemann, Volker, Neoptolemos, John P., Buechler, Markus W., Belka, Claus, Boeck, Stefan, Lerch, Markus M., Mayerle, Julia, Mahajan, Ujjwal M., Goni, Elisabetta, Langhoff, Enno, Li, Qi, Costello, Eithne, Greenhalf, William, Kruger, Stephan, Ormanns, Steffen, Halloran, Christopher, Ganeh, Paula, Marron, Manuela, Laemmerhirt, Felix, Zhao, Yue, Beyer, Georg, Weiss, Frank-Ulrich, Sendler, Matthias, Bruns, Christiane J., Kohlmann, Thomas, Kirchner, Thomas, Werner, Jens, D'Haese, Jan G., von Bergwelt, Michael, Heinemann, Volker, Neoptolemos, John P., Buechler, Markus W., Belka, Claus, Boeck, Stefan, Lerch, Markus M., and Mayerle, Julia

Abstract

Background: Cathepsin-D (CatD), owing to its dual role as a proteolytic enzyme and as a ligand, has been implicated in cancer progression. The role of CatD in pancreatic ductal adenocarcinoma is unknown. Methods: CatD expression quantified by immunohistochemistry of tumor-tissue microarrays of 403 resected pancreatic cancer patients from the ESPAC-Tplus trial, a translational study within the ESPAC (European Study Group for Pancreatic Cancer) trials, was dichotomously distributed to low and high H scores (cut off 22.35) for survival and multivariable analysis. The validation cohort (n = 69) was recruited based on the hazard ratio of CatD from ESPAC-Tplus. 5-fluorouracil-, and gemcitabine-resistant pancreatic cancer cell lines were employed for mechanistic experiments. All statistical tests were two-sided. Results: Median overall survival was 23.75 months and median overall survival for patients with high CatD expression was 21.09 (95% confidence interval [CI] = 17.31 to 24.80) months vs 27.20 (95% CI = 23.75 to 31.90) months for low CatD expression (chi(2)(LR), (1DF) = 4.00; P = .04). Multivariable analysis revealed CatD expression as a predictive marker in gemcitabine-treated (z stat = 2.33; P = .02) but not in 5-fluorouracil-treated (z stat = 0.21; P = .82) patients. An independent validation cohort confirmed CatD as a negative predictive marker for survival (chi(2)(LR), (1DF)= 6.80; P = .009) and as an independent predictive marker in gemcitabine-treated patients with a hazard ratio of 3.38 (95% CI = 1.36 to 8.38, P = .008). Overexpression of CatD was associated with a concomitant suppression of the acid sphingomyelinase, and silencing of CatD resulted in upregulation of acid sphingomyelinase with rescue of gemcitabine resistance. Conclusions: Adjuvant gemcitabine is less effective in pancreatic ductal adenocarcinoma with high CatD expression, and thus CatD could serve as a marker for biomarker-driven therapy.

Published
2020

30. Neoadjuvant therapy in elderly patients receiving FOLFIRINOX or gemcitabine/nab-paclitaxel for borderline resectable or locally advanced pancreatic cancer is feasible and lead to a similar oncological outcome compared to non-aged patients – Results of the RESPECT-Study

Author

Weniger, Maximilian, primary, Moir, John, additional, Damm, Marko, additional, Maggino, Laura, additional, Kordes, Maximilian, additional, Rosendahl, Jonas, additional, Ceyhan, Güralp O., additional, Schorn, Stephan, additional, Schmid, Daniel, additional, D'Haese, Jan G., additional, Böck, Stephan, additional, Kruger, Stephan, additional, Haas, Michael, additional, Röder, Falk, additional, Chiaro, Marco del, additional, Löhr, Matthias, additional, Tamburrino, Domenico, additional, Masini, Gaia, additional, Maisonneuve, Patrick, additional, Malleo, Giuseppe, additional, Salvia, Roberto, additional, and Charnley, Richard, additional

Published
2020
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31. Respect - A multicenter retrospective study on preoperative chemotherapy in locally advanced and borderline resectable pancreatic cancer

Author

Weniger, Maximilian, primary, Moir, John, additional, Damm, Marko, additional, Maggino, Laura, additional, Kordes, Maximilian, additional, Rosendahl, Jonas, additional, Ceyhan, Güralp O., additional, Schorn, Stephan, additional, Schmid, Daniel, additional, D'Haese, Jan G., additional, Werner, Jens, additional, Boeck, Stefan, additional, Kruger, Stephan, additional, Haas, Michael, additional, Roeder, Falk, additional, Friess, Helmut, additional, Chiaro, Marco del, additional, Löhr, Matthias, additional, Tamburrino, Domenico, additional, Falconi, Massimo, additional, Masini, Gaia, additional, Maisonneuve, Patrick, additional, Malleo, Giuseppe, additional, Salvia, Roberto, additional, Bassi, Claudio, additional, Charnley, Richard, additional, Algül, Hana, additional, Schmidt, Melissa, additional, Lange, Sebastian, additional, and Michl, Patrick, additional

Published
2020
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32. Protein Kinase D1, Reduced in Human Pancreatic Tumors, Increases Secretion of Small Extracellular Vesicles From Cancer Cells That Promote Metastasis to Lung in Mice

Author

Armacki, Milena, primary, Polaschek, Sandra, additional, Waldenmaier, Mareike, additional, Morawe, Mareen, additional, Ruhland, Claudia, additional, Schmid, Rebecca, additional, Lechel, André, additional, Tharehalli, Umesh, additional, Steup, Christoph, additional, Bektas, Yasin, additional, Li, Hongxia, additional, Kraus, Johann M., additional, Kestler, Hans A., additional, Kruger, Stephan, additional, Ormanns, Steffen, additional, Walther, Paul, additional, Eiseler, Tim, additional, and Seufferlein, Thomas, additional

Published
2020
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33. Bacterial lipopolysaccharide as negative predictor of gemcitabine efficacy in advanced pancreatic cancer – translational results from the AIO-PK0104 phase 3 study

Author

Guenther, Michael, primary, Haas, Michael, additional, Heinemann, Volker, additional, Kruger, Stephan, additional, Westphalen, Christoph Benedikt, additional, von Bergwelt-Baildon, Michael, additional, Mayerle, Julia, additional, Werner, Jens, additional, Kirchner, Thomas, additional, Boeck, Stefan, additional, and Ormanns, Steffen, additional

Published
2020
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35. Prolonged time to treatment initiation in advanced pancreatic cancer patients has no major effect on treatment outcome: a retrospective cohort study controlled for lead time bias and waiting time paradox

Author

Kruger, Stephan, primary, Schirle, Karoline, additional, Haas, Michael, additional, Crispin, Alexander, additional, Schirra, Jörg, additional, Mayerle, Julia, additional, D’Haese, Jan G., additional, Kunz, Wolfgang G., additional, Ricke, Jens, additional, Ormanns, Steffen, additional, Kirchner, Thomas, additional, Kobold, Sebastian, additional, Ilmer, Matthias, additional, Gebauer, Leonie, additional, Westphalen, Christoph B., additional, von Bergwelt-Baildon, Michael, additional, Werner, Jens, additional, Heinemann, Volker, additional, and Boeck, Stefan, additional

Published
2019
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36. Cathepsin D Expression and Gemcitabine Resistance in Pancreatic Cancer

Author

Mahajan, Ujjwal M, primary, Goni, Elisabetta, primary, Langhoff, Enno, primary, Li, Qi, primary, Costello, Eithne, primary, Greenhalf, William, primary, Kruger, Stephan, primary, Ormanns, Steffen, primary, Halloran, Christopher, primary, Ganeh, Paula, primary, Marron, Manuela, primary, Lämmerhirt, Felix, primary, Zhao, Yue, primary, Beyer, Georg, primary, Weiss, Frank-Ulrich, primary, Sendler, Matthias, primary, Bruns, Christiane J, primary, Kohlmann, Thomas, primary, Kirchner, Thomas, primary, Werner, Jens, primary, D’Haese, Jan G, primary, von Bergwelt-Baildon, Michael, primary, Heinemann, Volker, primary, Neoptolemos, John P, primary, Büchler, Markus W, primary, Belka, Claus, primary, Boeck, Stefan, primary, Lerch, Markus M, primary, and Mayerle, Julia, primary

Published
2019
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37. Cathepsin D expression mediates gemcitabine resistance in pancreatic cancer

Author

Mahajan, Ujjwal Mukund, primary, Goni, Elisabetta, additional, Langhoff, Enno, additional, Li, Qi, additional, Costello, Eithne, additional, Greenhalf, William, additional, Kruger, Stephan, additional, Ormanns, Steffen, additional, Halloran, Christopher, additional, Ganeh, Paula, additional, Marron, Manuela, additional, Lämmerhirt, Felix, additional, Zhao, Yue, additional, Beyer, Georg, additional, Weiss, Frank Ulrich, additional, Sendler, Matthias, additional, Bruns, Christine J., additional, Kohlmann, Thomas, additional, Kirchner, Thomas, additional, Werner, Jens, additional, D'Haese, Jan, additional, von Bergwelt-Baildon, Michael, additional, Heinemann, Volker, additional, Neoptolemos, John P., additional, Büchler, Markus W., additional, Belka, Claus, additional, Boeck, Stefan, additional, Lerch, Markus M., additional, and Mayerle, Julia, additional

Published
2019
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39. Contributors

Author

Ahmed, Mahmoud Salama, Angele, Martin K., Attia, Yasmeen M., Basso, João, Bouche, Gauthier, Chakraborti, Sohini, Chakravarthi, Pushpaveni, Chang, Hsuen-Wen Kate, Chang, Vincent H.S., Cheng, Bei, Cho, William C.S., D'Haese, Jan G., Dou, Q. Ping, Efferth, Thomas, Ewida, Heba, Fortuna, Ana, GNS, HemaSree, Hernández-Lemus, Enrique, Huang, Yingbo, Huang, R. Stephanie, Ilmer, Matthias, Khan, Harras J., Krishna Murthy, Mamatha, Kruger, Stephan, Lim, Hansaim, Mariam Jos, Swarna, Meheus, Lydie, Mendes, Maria, Nath, Aritro, Niess, Hanno, Ölgen, Süreyya, Othman Ahmed, Zainab Sabry, Pai, Rachana R, Pais, Alberto, Pantziarka, Pan, Pareek, Siddhika, PrasannaMarise, V Lakshmi, Renz, Bernhard W., Rohondia, Sagar O., Rombauts, Klara, Saraswathy, Ganesan Rajalekshmi, Sousa, João, Srinivasan, Narayanaswamy, To, Kenneth K.W., Vandeborne, Liese, Vitorino, Rui, Vitorino, Carla, Weniger, Maximilian, Werner, Jens, Westphalen, C. Benedikt, Wu, Yang, Xie, Lei, Xu, Peisheng, Yan, Ge, Zalavadiya, Nirav, and Zhang, Chun

Published
2020
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40. Prevalence and influence on outcome of HER2/neu, HER3 and NRG1 expression in patients with metastatic colorectal cancer

Author

Stahler, Arndt, primary, Heinemann, Volker, additional, Neumann, Jens, additional, Crispin, Alexander, additional, Schalhorn, Andreas, additional, Stintzing, Sebastian, additional, Giessen-Jung, Clemens, additional, Fischer von Weikersthal, Ludwig, additional, Vehling-Kaiser, Ursula, additional, Stauch, Martina, additional, Quietzsch, Detlef, additional, Holch, Julian W., additional, Kruger, Stephan, additional, Haas, Michael, additional, Michl, Marlies, additional, von Einem, Jobst, additional, Kirchner, Thomas, additional, Jung, Andreas, additional, and Modest, Dominik P., additional

Published
2017
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41. Switch in KRAS mutational status during an unusual course of disease in a patient with advanced pancreatic adenocarcinoma: implications for translational research

Author

Baechmann, Sibylle, primary, Ormanns, Steffen, additional, Haas, Michael, additional, Kruger, Stephan, additional, Remold, Anna, additional, Modest, Dominik Paul, additional, Kirchner, Thomas, additional, Jung, Andreas, additional, Werner, Jens, additional, Heinemann, Volker, additional, and Boeck, Stefan, additional

Published
2017
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42. Efficacy of gemcitabine with erlotinib in rash-positive patients selected according to eligibility for FOLFIRINOX.

Author

Haas, Michael, primary, Boeck, Stefan Hubert, additional, Siveke, Jens T., additional, Schenk, Michael, additional, Lerch, Markus, additional, Caca, Karel, additional, Freiberg-Richter, Jens, additional, Fischer von Weikersthal, Ludwig, additional, Kullmann, Frank, additional, Reinacher-Schick, Anke C., additional, Fuchs, Martin, additional, Ettrich, Thomas Jens, additional, Kanzler, Stephan, additional, Kunzmann, Volker, additional, Kruger, Stephan, additional, Westphalen, Benedikt, additional, Held, Swantje, additional, and Heinemann, Volker, additional

Published
2017
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44. Serum levels of soluble programmed death protein 1 (sPD-1) and soluble programmed death ligand 1 (sPD-L1) in advanced pancreatic cancer

Author

Kruger, Stephan, primary, Legenstein, Marie-Louise, additional, Rösgen, Verena, additional, Haas, Michael, additional, Modest, Dominik Paul, additional, Westphalen, Christoph Benedikt, additional, Ormanns, Steffen, additional, Kirchner, Thomas, additional, Heinemann, Volker, additional, Holdenrieder, Stefan, additional, and Boeck, Stefan, additional

Published
2017
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45. Extended RAS analysis and correlation with overall survival in advanced pancreatic cancer

Author

Haas, Michael, primary, Ormanns, Steffen, additional, Baechmann, Sibylle, additional, Remold, Anna, additional, Kruger, Stephan, additional, Westphalen, Christoph B, additional, Siveke, Jens T, additional, Wenzel, Patrick, additional, Schlitter, Anna Melissa, additional, Esposito, Irene, additional, Quietzsch, Detlef, additional, Clemens, Michael R, additional, Kettner, Erika, additional, Laubender, Ruediger P, additional, Jung, Andreas, additional, Kirchner, Thomas, additional, Boeck, Stefan, additional, and Heinemann, Volker, additional

Published
2017
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46. Alternative Donor Transplantation Using Intensified Conditioning, T-Cell-Replete HLA-Haploidentical Grafts and Post-Transplantation Cyclophosphamide in the Treatment of High-Risk and Advanced ALL: Feasibility and Outcome

Author

Zoellner, Anna-Katharina, primary, Prevalsek, Dusan, additional, Köhnke, Thomas, additional, Fritsch, Susanne, additional, Schulz, Christoph, additional, Hubmann, Max, additional, Lippl, Stephanie, additional, Kruger, Stephan, additional, Häbe, Sarah, additional, Berking, Sophie, additional, Fraccaroli, Alessia, additional, Ledderose, Georg, additional, Stemmler, Hans-Joachim, additional, Spiekermann, Karsten, additional, Hiddemann, Wolfgang, additional, Bug, Gesine, additional, Hausmann, Andreas, additional, Schmid, Christoph, additional, Albert, Michael H., additional, and Tischer, Johanna, additional

Published
2016
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47. Impact of SPARC expression on outcome in patients with advanced pancreatic cancer not receiving nab-paclitaxel: a pooled analysis from prospective clinical and translational trials

Author

Ormanns, Steffen, primary, Haas, Michael, additional, Baechmann, Sibylle, additional, Altendorf-Hofmann, Annelore, additional, Remold, Anna, additional, Quietzsch, Detlef, additional, Clemens, Michael R, additional, Bentz, Martin, additional, Geissler, Michael, additional, Lambertz, Helmut, additional, Kruger, Stephan, additional, Kirchner, Thomas, additional, Heinemann, Volker, additional, and Boeck, Stefan, additional

Published
2016
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49. Cancer cell-derived IL-1α induces CCL22 and the recruitment of regulatory T cells

Author

Wiedemann, Gabriela Maria, primary, Knott, Max Martin Ludwig, additional, Vetter, Viola Katharina, additional, Rapp, Moritz, additional, Haubner, Sascha, additional, Fesseler, Julia, additional, Kühnemuth, Benjamin, additional, Layritz, Patrick, additional, Thaler, Raffael, additional, Kruger, Stephan, additional, Ormanns, Steffen, additional, Mayr, Doris, additional, Endres, Stefan, additional, and Anz, David, additional

Published
2016
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50. T-Cell-Replete HLA-Haploidentical Transplantation Using Post-Transplantation High-Dose Cyclophosphamide in High Risk and Advanced ALL: Feasibility and Early Outcome

Author

Zoellner, Anna-Katharina, primary, Fritsch, Susanne, additional, Prevalsek, Dusan, additional, Köhnke, Thomas, additional, Hubmann, Max, additional, Lippl, Stephanie, additional, Kruger, Stephan, additional, Hellmuth, Johannes, additional, Mumm, Friederike, additional, Ledderose, Georg, additional, Barlow, Sophie, additional, Subklewe, Marion, additional, Spiekermann, Karsten, additional, Hiddemann, Wolfgang, additional, Albert, Michael H., additional, Schmid, Christoph, additional, Hausmann, Andreas, additional, and Tischer, Johanna, additional

Published
2016
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