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531 results on '"Krug, Utz"'

2. Prognostic impact of CEBPA mutational subgroups in adult AML

Author

Georgi, Julia-Annabell, Stasik, Sebastian, Kramer, Michael, Meggendorfer, Manja, Röllig, Christoph, Haferlach, Torsten, Valk, Peter, Linch, David, Herold, Tobias, Duployez, Nicolas, Taube, Franziska, Middeke, Jan Moritz, Platzbecker, Uwe, Serve, Hubert, Baldus, Claudia D., Muller-Tidow, Carsten, Haferlach, Claudia, Koch, Sarah, Berdel, Wolfgang E., Woermann, Bernhard J., Krug, Utz, Braess, Jan, Hiddemann, Wolfgang, Spiekermann, Karsten, Boertjes, Emma L., Hills, Robert K., Burnett, Alan, Ehninger, Gerhard, Metzeler, Klaus, Rothenberg-Thurley, Maja, Dufour, Annika, Dombret, Hervé, Pautas, Cecile, Preudhomme, Claude, Fenwarth, Laurene, Bornhäuser, Martin, Gale, Rosemary, and Thiede, Christian

Published
2024
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3. Sex-associated differences in frequencies and prognostic impact of recurrent genetic alterations in adult acute myeloid leukemia (Alliance, AMLCG)

Author

Ozga, Michael, Nicolet, Deedra, Mrózek, Krzysztof, Yilmaz, Ayse S., Kohlschmidt, Jessica, Larkin, Karilyn T., Blachly, James S., Oakes, Christopher C., Buss, Jill, Walker, Christopher J., Orwick, Shelley, Jurinovic, Vindi, Rothenberg-Thurley, Maja, Dufour, Annika, Schneider, Stephanie, Sauerland, Maria Cristina, Görlich, Dennis, Krug, Utz, Berdel, Wolfgang E., Woermann, Bernhard J., Hiddemann, Wolfgang, Braess, Jan, Subklewe, Marion, Spiekermann, Karsten, Carroll, Andrew J., Blum, William G., Powell, Bayard L., Kolitz, Jonathan E., Moore, Joseph O., Mayer, Robert J., Larson, Richard A., Uy, Geoffrey L., Stock, Wendy, Metzeler, Klaus H., Grimes, H. Leighton, Byrd, John C., Salomonis, Nathan, Herold, Tobias, Mims, Alice S., and Eisfeld, Ann-Kathrin

Published
2024
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4. Secondary-type mutations do not impact outcome in NPM1-mutated acute myeloid leukemia – implications for the European LeukemiaNet risk classification

Author

Eckardt, Jan-Niklas, Bill, Marius, Rausch, Christian, Metzeler, Klaus, Spiekermann, Karsten, Stasik, Sebastian, Sauer, Tim, Scholl, Sebastian, Hochhaus, Andreas, Crysandt, Martina, Brümmendorf, Tim H., Krug, Utz, Wörmann, Bernhard, Hiddemann, Wolfgang, Görlich, Dennis, Sauerland, Cristina, Steffen, Björn, Einsele, Hermann, Neubauer, Andreas, Burchert, Andreas, Schäfer-Eckart, Kerstin, Berdel, Wolfgang E., Schliemann, Christoph, Krause, Stefan W., Hänel, Mathias, Hanoun, Maher, Kaufmann, Martin, Fransecky, Lars, Braess, Jan, Ruhnke, Leo, Schetelig, Johannes, Middeke, Jan Moritz, Serve, Hubert, Baldus, Claudia D., Platzbecker, Uwe, Müller-Tidow, Carsten, Bornhäuser, Martin, Herold, Tobias, Thiede, Christian, and Röllig, Christoph

Published
2023
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5. Systematic symptom screening in patients with advanced cancer treated in certified oncology centers: results of the prospective multicenter German KeSBa project

Author

Braulke, Friederike, Para, Servet, Alt-Epping, Bernd, Tewes, Mitra, Bäumer, Markus, Haberland, Birgit, Mayer-Steinacker, Regine, Hopprich, Anne, de Wit, Maike, Grabe, Michaela, Bender-Säbelkampf, Sophia, Weßling, Caroline, Aulmann, Christoph, Gerlach, Christina, Regincos, Pascale, Fischer, Ferdinand, Haarmann, Soraya, Huys, Tatjana, Drygas, Sabine, Rambau, Anett, Kiani, Alexander, Schnabel, Astrid, Buhl, Christoph, Seipke, Stefanie, Hiemer, Sonja, Polata, Silke, Meßmann, Maximilian, Hansmeier, Anna, Anastasiadou, Louiza, Letsch, Anne, Wecht, Daniel, Hellberg-Naegele, Matthias, Krug, Utz, Wedding, Ulrich, and van Oorschot, Birgitt

Published
2023
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6. UBTF tandem duplications are rare but recurrent alterations in adult AML and associated with younger age, myelodysplasia, and inferior outcome

Author

Georgi, Julia-Annabell, Stasik, Sebastian, Eckardt, Jan-Niklas, Zukunft, Sven, Hartwig, Marita, Röllig, Christoph, Middeke, Jan Moritz, Oelschlägel, Uta, Krug, Utz, Sauer, Tim, Scholl, Sebastian, Hochhaus, Andreas, Brümmendorf, Tim H., Naumann, Ralph, Steffen, Björn, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W., Hänel, Mathias, Noppeney, Richard, Kaiser, Ulrich, Baldus, Claudia D., Kaufmann, Martin, Müller-Tidow, Carsten, Platzbecker, Uwe, Berdel, Wolfgang E., Serve, Hubert, Ehninger, Gerhard, Bornhäuser, Martin, Schetelig, Johannes, Kroschinsky, Frank, and Thiede, Christian

Published
2023
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7. Unsupervised meta-clustering identifies risk clusters in acute myeloid leukemia based on clinical and genetic profiles

Author

Eckardt, Jan-Niklas, Röllig, Christoph, Metzeler, Klaus, Heisig, Peter, Stasik, Sebastian, Georgi, Julia-Annabell, Kroschinsky, Frank, Stölzel, Friedrich, Platzbecker, Uwe, Spiekermann, Karsten, Krug, Utz, Braess, Jan, Görlich, Dennis, Sauerland, Cristina, Woermann, Bernhard, Herold, Tobias, Hiddemann, Wolfgang, Müller-Tidow, Carsten, Serve, Hubert, Baldus, Claudia D., Schäfer-Eckart, Kerstin, Kaufmann, Martin, Krause, Stefan W., Hänel, Mathias, Berdel, Wolfgang E., Schliemann, Christoph, Mayer, Jiri, Hanoun, Maher, Schetelig, Johannes, Wendt, Karsten, Bornhäuser, Martin, Thiede, Christian, and Middeke, Jan Moritz

Published
2023
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9. Different treatment strategies versus a common standard arm (CSA) in patients with newly diagnosed AML over the age of 60 years: a randomized German inter-group study

Author

Niederwieser, Dietger, Lang, Thomas, Krahl, Rainer, Heinicke, Thomas, Maschmeyer, Georg, Al-Ali, Haifa Kathrin, Schwind, Sebastian, Jentzsch, Madlen, Cross, Michael, Kahl, Christoph, Wolf, Hans-Heinrich, Sayer, Herbert, Schulze, Antje, Dreger, Peter, Hegenbart, Ute, Krämer, Alwin, Junghanss, Christian, Mügge, Lars-Olof, Hähling, Detlev, Hirt, Carsten, Späth, Christian, Peter, Norma, Opitz, Bernhard, Florschütz, Axel, Reifenrath, Kolja, Zojer, Niklas, Scholl, Sebastian, Pönisch, Wolfram, Heyn, Simone, Vucinic, Vladan, Hochhaus, Andreas, Aul, Carlo, Giagounidis, Aristoteles, Balleisen, Leopold, Oldenkott, Bernd, Staib, Peter, Kiehl, Michael, Schütte, Wolfgang, Naumann, Ralph, Eimermacher, Hartmut, Dörken, Bernd, Sauerland, Cristina, Lengfelder, Eva, Hiddemann, Wolfgang, Wörmann, Bernhard, Müller-Tidow, Carsten, Serve, Hubert, Schliemann, Christoph, Hehlmann, Rüdiger, Berdel, Wolfgang E., Pfirrmann, Markus, Krug, Utz, and Hoffmann, Verena S.

Published
2023
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10. A randomized phase 2 trial of nintedanib and low-dose cytarabine in elderly patients with acute myeloid leukemia ineligible for intensive chemotherapy

Author

Berdel, Andrew F., Koch, Raphael, Gerss, Joachim, Hentrich, Marcus, Peceny, Rudolf, Bartscht, Tobias, Steffen, Björn, Bischoff, Marina, Spiekermann, Karsten, Angenendt, Linus, Mikesch, Jan-Henrik, Kewitz, Tobias, Butterfass-Bahloul, Trude, Serve, Hubert, Lenz, Georg, Berdel, Wolfgang E., Krug, Utz, and Schliemann, Christoph

Published
2023
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11. Impact of IDH1 and IDH2 mutational subgroups in AML patients after allogeneic stem cell transplantation

Author

Kunadt, Desiree, Stasik, Sebastian, Metzeler, Klaus H., Röllig, Christoph, Schliemann, Christoph, Greif, Philipp A., Spiekermann, Karsten, Rothenberg-Thurley, Maja, Krug, Utz, Braess, Jan, Krämer, Alwin, Hochhaus, Andreas, Scholl, Sebastian, Hilgendorf, Inken, Brümmendorf, Tim H., Jost, Edgar, Steffen, Björn, Bug, Gesine, Einsele, Hermann, Görlich, Dennis, Sauerland, Cristina, Schäfer-Eckart, Kerstin, Krause, Stefan W., Hänel, Mathias, Hanoun, Maher, Kaufmann, Martin, Wörmann, Bernhard, Kramer, Michael, Sockel, Katja, Egger-Heidrich, Katharina, Herold, Tobias, Ehninger, Gerhard, Burchert, Andreas, Platzbecker, Uwe, Berdel, Wolfgang E., Müller-Tidow, Carsten, Hiddemann, Wolfgang, Serve, Hubert, Stelljes, Matthias, Baldus, Claudia D., Neubauer, Andreas, Schetelig, Johannes, Thiede, Christian, Bornhäuser, Martin, Middeke, Jan M., and Stölzel, Friedrich

Published
2022
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12. Differential impact of IDH1/2 mutational subclasses on outcome in adult AML: results from a large multicenter study

Author

Middeke, Jan M., Metzeler, Klaus H., Röllig, Christoph, Krämer, Michael, Eckardt, Jan-Niklas, Stasik, Sebastian, Greif, Philipp A., Spiekermann, Karsten, Rothenberg-Thurley, Maja, Krug, Utz, Braess, Jan, Krämer, Alwin, Hochhaus, Andreas, Brümmendorf, Tim H., Naumann, Ralph, Steffen, Björn, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Görlich, Dennis, Sauerland, Cristina, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W., Hänel, Mathias, Frickhofen, Norbert, Noppeney, Richard, Kaiser, Ulrich, Kaufmann, Martin, Kunadt, Desiree, Wörmann, Bernhard, Sockel, Katja, von Bonin, Malte, Herold, Tobias, Müller-Tidow, Carsten, Platzbecker, Uwe, Berdel, Wolfgang E., Serve, Hubert, Baldus, Claudia D., Ehninger, Gerhard, Schetelig, Johannes, Hiddemann, Wolfgang, Bornhäuser, Martin, Stölzel, Friedrich, and Thiede, Christian

Published
2022
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13. CEBPA mutations in 4708 patients with acute myeloid leukemia: differential impact of bZIP and TAD mutations on outcome

Author

Taube, Franziska, Georgi, Julia Annabell, Kramer, Michael, Stasik, Sebastian, Middeke, Jan Moritz, Röllig, Christoph, Krug, Utz, Krämer, Alwin, Scholl, Sebastian, Hochhaus, Andreas, Brümmendorf, Tim H., Naumann, Ralph, Petzold, Andreas, Mulet-Lazaro, Roger, Valk, Peter J.M., Steffen, Björn, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W., Hänel, Mathias, Noppeney, Richard, Kaiser, Ulrich, Baldus, Claudia D., Kaufmann, Martin, Herold, Sylvia, Stölzel, Friedrich, Sockel, Katja, von Bonin, Malte, Müller-Tidow, Carsten, Platzbecker, Uwe, Berdel, Wolfgang E., Serve, Hubert, Ehninger, Gerhard, Bornhäuser, Martin, Schetelig, Johannes, and Thiede, Christian

Published
2022
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14. A clinically applicable gene expression–based score predicts resistance to induction treatment in acute myeloid leukemia

Author

Moser, Christian, Jurinovic, Vindi, Sagebiel-Kohler, Sabine, Ksienzyk, Bianka, Batcha, Aarif M.N., Dufour, Annika, Schneider, Stephanie, Rothenberg-Thurley, Maja, Sauerland, Cristina M., Görlich, Dennis, Berdel, Wolfgang E., Krug, Utz, Mansmann, Ulrich, Hiddemann, Wolfgang, Braess, Jan, Spiekermann, Karsten, Greif, Philipp A., Vosberg, Sebastian, Metzeler, Klaus H., Kumbrink, Jörg, and Herold, Tobias

Published
2021
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15. Friday leukemia—a structural phenomenon

Author

Rausch, Christian, primary, Arnreich, Chiara, additional, Rothenberg-Thurley, Maja, additional, Dufour, Annika, additional, Schneider, Stephanie, additional, Gittinger, Hanna, additional, Bücklein, Veit, additional, Subklewe, Marion, additional, Sauerland, Cristina, additional, Görlich, Dennis, additional, Krug, Utz, additional, Berdel, Wolfgang E., additional, Wörmann, Bernhard J., additional, Hiddemann, Wolfgang, additional, Braess, Jan, additional, von Bergwelt-Baildon, Michael, additional, Spiekermann, Karsten, additional, Metzeler, Klaus H., additional, and Herold, Tobias, additional

Published
2024
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16. Prognostic impact of CEBPA mutational subgroups in adult AML

Author

Georgi, Julia Annabell, Stasik, Sebastian, Kramer, Michael, Meggendorfer, Manja, Röllig, Christoph, Haferlach, Torsten, Valk, Peter, Linch, David, Herold, Tobias, Duployez, Nicolas, Taube, Franziska, Middeke, Jan Moritz, Platzbecker, Uwe, Serve, Hubert, Baldus, Claudia D., Muller-Tidow, Carsten, Haferlach, Claudia, Koch, Sarah, Berdel, Wolfgang E., Woermann, Bernhard J., Krug, Utz, Braess, Jan, Hiddemann, Wolfgang, Spiekermann, Karsten, Boertjes, Emma L., Hills, Robert K., Burnett, Alan, Ehninger, Gerhard, Metzeler, Klaus, Rothenberg-Thurley, Maja, Dufour, Annika, Dombret, Hervé, Pautas, Cecile, Preudhomme, Claude, Fenwarth, Laurene, Bornhäuser, Martin, Gale, Rosemary, Thiede, Christian, Georgi, Julia Annabell, Stasik, Sebastian, Kramer, Michael, Meggendorfer, Manja, Röllig, Christoph, Haferlach, Torsten, Valk, Peter, Linch, David, Herold, Tobias, Duployez, Nicolas, Taube, Franziska, Middeke, Jan Moritz, Platzbecker, Uwe, Serve, Hubert, Baldus, Claudia D., Muller-Tidow, Carsten, Haferlach, Claudia, Koch, Sarah, Berdel, Wolfgang E., Woermann, Bernhard J., Krug, Utz, Braess, Jan, Hiddemann, Wolfgang, Spiekermann, Karsten, Boertjes, Emma L., Hills, Robert K., Burnett, Alan, Ehninger, Gerhard, Metzeler, Klaus, Rothenberg-Thurley, Maja, Dufour, Annika, Dombret, Hervé, Pautas, Cecile, Preudhomme, Claude, Fenwarth, Laurene, Bornhäuser, Martin, Gale, Rosemary, and Thiede, Christian

Abstract

Despite recent refinements in the diagnostic and prognostic assessment of CEBPA mutations in AML, several questions remain open, i.e. implications of different types of basic region leucin zipper (bZIP) mutations, the role of co-mutations and the allelic state. Using pooled primary data analysis on 1010 CEBPA-mutant adult AML patients, a comparison was performed taking into account the type of mutation (bZIP: either typical in-frame insertion/deletion (InDel) mutations (bZIP InDel), frameshift InDel or nonsense mutations inducing translational stop (bZIP STOP) or single base-pair missense alterations (bZIP ms), and transcription activation domain (TAD) mutations) and the allelic state (single (smCEBPA) vs. double mutant (dmCEBPA)). Only bZIP InDel patients had significantly higher rates of complete remission and longer relapse free and overall survival (OS) compared with all other CEBPA-mutant subgroups. Moreover, co-mutations in bZIP InDel patients (e.g. GATA2, FLT3, WT1 as well as ELN2022 adverse risk aberrations) had no independent impact on OS, whereas in non-bZIP InDel patients, grouping according to ELN2022 recommendations added significant prognostic information. In conclusion, these results demonstrate bZIP InDel mutations to be the major independent determinant of outcome in CEBPA-mutant AML, thereby refining current classifications according to WHO (including all dmCEBPA and smCEBPA bZIP) as well as ELN2022 and ICC recommendations (including CEBPA bZIP ms). (Figure presented.)

Published
2024

17. Sex-associated differences in frequencies and prognostic impact of recurrent genetic alterations in adult acute myeloid leukemia (Alliance, AMLCG)

Author

Ozga, Michael, primary, Nicolet, Deedra, additional, Mrózek, Krzysztof, additional, Yilmaz, Ayse S., additional, Kohlschmidt, Jessica, additional, Larkin, Karilyn T., additional, Blachly, James S., additional, Oakes, Christopher C., additional, Buss, Jill, additional, Walker, Christopher J., additional, Orwick, Shelley, additional, Jurinovic, Vindi, additional, Rothenberg-Thurley, Maja, additional, Dufour, Annika, additional, Schneider, Stephanie, additional, Sauerland, Maria Cristina, additional, Görlich, Dennis, additional, Krug, Utz, additional, Berdel, Wolfgang E., additional, Woermann, Bernhard J., additional, Hiddemann, Wolfgang, additional, Braess, Jan, additional, Subklewe, Marion, additional, Spiekermann, Karsten, additional, Carroll, Andrew J., additional, Blum, William G., additional, Powell, Bayard L., additional, Kolitz, Jonathan E., additional, Moore, Joseph O., additional, Mayer, Robert J., additional, Larson, Richard A., additional, Uy, Geoffrey L., additional, Stock, Wendy, additional, Metzeler, Klaus H., additional, Grimes, H. Leighton, additional, Byrd, John C., additional, Salomonis, Nathan, additional, Herold, Tobias, additional, Mims, Alice S., additional, and Eisfeld, Ann-Kathrin, additional

Published
2023
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18. Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia

Author

Herold, Tobias, Rothenberg-Thurley, Maja, Grunwald, Victoria V., Janke, Hanna, Goerlich, Dennis, Sauerland, Maria C., Konstandin, Nikola P., Dufour, Annika, Schneider, Stephanie, Neusser, Michaela, Ksienzyk, Bianka, Greif, Philipp A., Subklewe, Marion, Faldum, Andreas, Bohlander, Stefan K., Braess, Jan, Wörmann, Bernhard, Krug, Utz, Berdel, Wolfgang E., Hiddemann, Wolfgang, Spiekermann, Karsten, and Metzeler, Klaus H.

Published
2020
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19. The neuropeptide receptor calcitonin receptor-like (CALCRL) is a potential therapeutic target in acute myeloid leukemia

Author

Angenendt, Linus, Bormann, Eike, Pabst, Caroline, Alla, Vijay, Görlich, Dennis, Braun, Leonie, Dohlich, Kim, Schwöppe, Christian, Bohlander, Stefan K., Arteaga, Maria Francisca, Wethmar, Klaus, Hartmann, Wolfgang, Angenendt, Adrian, Kessler, Torsten, Mesters, Rolf M., Stelljes, Matthias, Rothenberg-Thurley, Maja, Spiekermann, Karsten, Hébert, Josée, Sauvageau, Guy, Valk, Peter J. M., Löwenberg, Bob, Serve, Hubert, Müller-Tidow, Carsten, Lenz, Georg, Wörmann, Bernhard J., Sauerland, M. Christina, Hiddemann, Wolfgang, Berdel, Wolfgang E., Krug, Utz, Metzeler, Klaus H., Mikesch, Jan-Henrik, Herold, Tobias, and Schliemann, Christoph

Published
2019
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21. P446: COMPREHENSIVE CHARACTERIZATION OF DIFFERENTIAL GENE EXPRESSION AND ISOFORM USAGE IN SPLICING FACTOR-MUTATED ACUTE MYELOID LEUKEMIA USING LONG-READ SEQUENCING

Author

Thieme, Susanne, primary, Graf, Alexander, additional, Krebs, Stefan, additional, Blum, Helmut, additional, Solovey, Maria, additional, Ziemann, Frank, additional, Christ, Jonathan, additional, Rothenberg-Thurley, Maja, additional, Dufour, Annika, additional, Schneider, Stephanie, additional, Cristina Sauerland, Maria, additional, Görlich, Dennis, additional, Krug, Utz, additional, Berdel, Wolfgang E., additional, Wörmann, Bernhard, additional, Hiddemann, Wolfgang, additional, Braess, Jan, additional, Spiekermann, Karsten, additional, Metzeler, Klaus, additional, Mannsmann, Ulrich, additional, and Herold, Tobias, additional

Published
2023
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22. P434: MYELODYSPLASIA-RELATED MUTATIONS IN THE NEW ELN CLASSIFICATION: DOES CLONAL SIZE PLAY A ROLE?

Author

Rausch, Christian, primary, Rothenberg-Thurley, Maja, additional, Dufour, Annika, additional, Schneider, Stephanie, additional, Gittinger, Hanna, additional, Sauerland, Cristina, additional, Görlich, Dennis, additional, Krug, Utz, additional, Berdel, Wolfgang E., additional, Woermann, Bernhard J., additional, Hiddemann, Wolfgang, additional, Braess, Jan, additional, von Bergwelt-Baildon, Michael, additional, Spiekermann, Karsten, additional, Herold, Tobias, additional, and Metzeler, Klaus H., additional

Published
2023
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23. P457: COMPLEX CARYOTYPE IS AN INDEPENDENT RISK FACTOR IN TP53-MUTATED AML

Author

Rausch, Christian, primary, Rothenberg-Thurley, Maja, additional, Dufour, Annika, additional, Schneider, Stephanie, additional, Gittinger, Hanna, additional, Sauerland, Cristina, additional, Görlich, Dennis, additional, Krug, Utz, additional, Berdel, Wolfgang E., additional, Woermann, Bernhard E., additional, Hiddemann, Wolfgang, additional, Braess, Jan, additional, von Bergwelt-Baildon, Michael, additional, Spiekermann, Karsten, additional, Herold, Tobias, additional, and Metzeler, Klaus H., additional

Published
2023
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24. S138: VALIDATION OF THE REVISED 2022 EUROPEAN LEUKEMIANET (ELN) RISK STRATIFICATION IN ADULT PATIENTS WITH ACUTE MYELOID LEUKEMIA

Author

Bill, Marius, primary, Ruhnke, Leo, additional, Zukunft, Sven, additional, Schäfer, Silvia, additional, Eckardt, Jan-Niklas, additional, Stasik, Sebastian, additional, Hanoun, Maher, additional, Schroeder, Thomas, additional, Fransecky, Lars, additional, Steffen, Björn, additional, Krause, Stefan W., additional, Scholl, Sebastian, additional, Hochhaus, Andreas, additional, Sauer, Tim, additional, Kraus, Sabrina, additional, Schäfer-Eckart, Kerstin, additional, Kaufmann, Martin, additional, Jost, Edgar, additional, Brümmendorf, Tim H, additional, Schliemann, Christoph, additional, Mikesch, Jan-Henrik, additional, Krug, Utz, additional, Hänel, Mathias, additional, Morgner, Anke, additional, Schaich, Markus, additional, Neubauer, Andreas, additional, Repp, Roland, additional, Niemann, Dirk, additional, Seggewiss-Bernhardt, Ruth, additional, Meinhardt, Achim, additional, Kullmer, Johannes, additional, Kaiser, Ulrich, additional, Blau, Wolfgang, additional, Kiani, Alexander, additional, Grigoleit, Götz Ulrich, additional, Giagounidis, Aristoteles, additional, Wurm, Alexander, additional, Altmann, Heidi, additional, Middeke, Jan Moritz, additional, Schetelig, Johannes, additional, Müller-Tidow, Carsten, additional, Stölzel, Friedrich, additional, Baldus, Claudia, additional, Platzbecker, Uwe, additional, Serve, Hubert, additional, Bornhäuser, Martin, additional, Thiede, Christian, additional, and Röllig, Christoph, additional

Published
2023
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26. Double-Blind, Placebo Controlled, Randomized, Multicenter, Phase II Study to Assess the Efficacy of the High Affinity CXCR4 Inhibitor BL-8040 As Addition to Consolidation Therapy in AML By the SAL and OSHO Leukemia Study Groups

Author

Jaramillo Segura, Sonia, Wass, Maxi, Schaffrath, Judith, Rieger, Kathrin, Nogai, Axel, Hänel, Mathias, Herbst, Regina, Stölzel, Friedrich, Röllig, Christoph, Jost, Edgar, Schlenk, Richard F., Noppeney, Richard, Brandts, Christian H., Krug, Utz, Götze, Katharina S., Buske, Sebastian, Florschütz, Axel, Schubert, Jörg, Opitz, Bernhard, Mohren, Martin, Eßeling, Eva, von Witzendorff, Stephan, Subklewe, Marion, Kaufmann, Martin, Frickhofen, Norbert, Scholz, Christian W., Schäfer-Eckart, Kerstin, Kunzmann, Volker, Schmidt-Hieber, Martin, Sayer, Herbert G., Rank, Andreas, Hemmati, Philipp, Schüler, Frank, Kowoll, Simone, Scheller, Marina, Steighardt, Jörg, Edemir, Bayram, Müller, Lutz Peter, Gliko-Kabir, Irit, Ludwig-Kraus, Beatrice, Edemir, Sabine, Sorani, Ella, Binder, Mascha, Vainstein, Abi, Kadosh, Shaul, Gromann, Cora, Wienke, Andreas, Baldus, Claudia D., Platzbecker, Uwe, Serve, Hubert, Bornhäuser, Martin, Junghanss, Christian, and Müller-Tidow, Carsten

Subjects
Immunology, ddc:610, Cell Biology, Hematology, Biochemistry
Published
2022

27. Validation and refinement of the 2022 European LeukemiaNet genetic risk stratification of acute myeloid leukemia

Author

Rausch, Christian, primary, Rothenberg-Thurley, Maja, additional, Dufour, Annika, additional, Schneider, Stephanie, additional, Gittinger, Hanna, additional, Sauerland, Cristina, additional, Görlich, Dennis, additional, Krug, Utz, additional, Berdel, Wolfgang E., additional, Woermann, Bernhard J., additional, Hiddemann, Wolfgang, additional, Braess, Jan, additional, von Bergwelt-Baildon, Michael, additional, Spiekermann, Karsten, additional, Herold, Tobias, additional, and Metzeler, Klaus H., additional

Published
2023
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28. Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia

Author

Metzeler, Klaus H., Herold, Tobias, Rothenberg-Thurley, Maja, Amler, Susanne, Sauerland, Maria C., Görlich, Dennis, Schneider, Stephanie, Konstandin, Nikola P., Dufour, Annika, Bräundl, Kathrin, Ksienzyk, Bianka, Zellmeier, Evelyn, Hartmann, Luise, Greif, Philipp A., Fiegl, Michael, Subklewe, Marion, Bohlander, Stefan K., Krug, Utz, Faldum, Andreas, Berdel, Wolfgang E., Wörmann, Bernhard, Büchner, Thomas, Hiddemann, Wolfgang, Braess, Jan, and Spiekermann, Karsten

Published
2016
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29. Addition of sorafenib versus placebo to standard therapy in patients aged 60 years or younger with newly diagnosed acute myeloid leukaemia (SORAML): a multicentre, phase 2, randomised controlled trial

Author

Röllig, Christoph, Serve, Hubert, Hüttmann, Andreas, Noppeney, Richard, Müller-Tidow, Carsten, Krug, Utz, Baldus, Claudia D, Brandts, Christian H, Kunzmann, Volker, Einsele, Hermann, Krämer, Alwin, Schäfer-Eckart, Kerstin, Neubauer, Andreas, Burchert, Andreas, Giagounidis, Aristoteles, Krause, Stefan W, Mackensen, Andreas, Aulitzky, Walter, Herbst, Regina, Hänel, Mathias, Kiani, Alexander, Frickhofen, Norbert, Kullmer, Johannes, Kaiser, Ulrich, Link, Hartmut, Geer, Thomas, Reichle, Albert, Junghanß, Christian, Repp, Roland, Heits, Frank, Dürk, Heinz, Hase, Jana, Klut, Ina-Maria, Illmer, Thomas, Bornhäuser, Martin, Schaich, Markus, Parmentier, Stefani, Görner, Martin, Thiede, Christian, von Bonin, Malte, Schetelig, Johannes, Kramer, Michael, Berdel, Wolfgang E, and Ehninger, Gerhard

Published
2015
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30. Prognostic impact of CEBPAmutational subgroups in adult AML

Author

Georgi, Julia-Annabell, Stasik, Sebastian, Kramer, Michael, Meggendorfer, Manja, Röllig, Christoph, Haferlach, Torsten, Valk, Peter, Linch, David, Herold, Tobias, Duployez, Nicolas, Taube, Franziska, Middeke, Jan Moritz, Platzbecker, Uwe, Serve, Hubert, Baldus, Claudia D., Muller-Tidow, Carsten, Haferlach, Claudia, Koch, Sarah, Berdel, Wolfgang E., Woermann, Bernhard J., Krug, Utz, Braess, Jan, Hiddemann, Wolfgang, Spiekermann, Karsten, Boertjes, Emma L., Hills, Robert K., Burnett, Alan, Ehninger, Gerhard, Metzeler, Klaus, Rothenberg-Thurley, Maja, Dufour, Annika, Dombret, Hervé, Pautas, Cecile, Preudhomme, Claude, Fenwarth, Laurene, Bornhäuser, Martin, Gale, Rosemary, and Thiede, Christian

Abstract

Despite recent refinements in the diagnostic and prognostic assessment of CEBPAmutations in AML, several questions remain open, i.e. implications of different types of basic region leucin zipper (bZIP) mutations, the role of co-mutations and the allelic state. Using pooled primary data analysis on 1010 CEBPA-mutant adult AML patients, a comparison was performed taking into account the type of mutation (bZIP: either typical in-frame insertion/deletion (InDel) mutations (bZIPInDel), frameshift InDel or nonsense mutations inducing translational stop (bZIPSTOP) or single base-pair missense alterations (bZIPms), and transcription activation domain (TAD) mutations) and the allelic state (single (smCEBPA) vs. double mutant (dmCEBPA)). Only bZIPInDelpatients had significantly higher rates of complete remission and longer relapse free and overall survival (OS) compared with all other CEBPA-mutant subgroups. Moreover, co-mutations in bZIPInDelpatients (e.g. GATA2, FLT3, WT1as well as ELN2022 adverse risk aberrations) had no independent impact on OS, whereas in non-bZIPInDelpatients, grouping according to ELN2022 recommendations added significant prognostic information. In conclusion, these results demonstrate bZIPInDelmutations to be the major independent determinant of outcome in CEBPA-mutant AML, thereby refining current classifications according to WHO (including all dmCEBPAand smCEBPAbZIP) as well as ELN2022 and ICC recommendations (including CEBPAbZIPms).

Published
2024
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31. A randomized phase 2 trial of nintedanib and low-dose cytarabine in elderly patients with acute myeloid leukemia ineligible for intensive chemotherapy

Author

Berdel, Andrew F., primary, Koch, Raphael, additional, Gerss, Joachim, additional, Hentrich, Marcus, additional, Peceny, Rudolf, additional, Bartscht, Tobias, additional, Steffen, Björn, additional, Bischoff, Marina, additional, Spiekermann, Karsten, additional, Angenendt, Linus, additional, Mikesch, Jan-Henrik, additional, Kewitz, Tobias, additional, Butterfass-Bahloul, Trude, additional, Serve, Hubert, additional, Lenz, Georg, additional, Berdel, Wolfgang E., additional, Krug, Utz, additional, and Schliemann, Christoph, additional

Published
2022
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32. German AMLCG-Survivorship Study: Anxiety and Depression Symptoms in AML Long-Term Survivors

Author

Görlich, Dennis, primary, Telzerow, Eva, additional, Sauerland, Maria Cristina, additional, Moret, Anna Sophia, additional, Rothenberg-Thurley, Maja, additional, Mumm, Friederike H.A., additional, Amler, Susanne, additional, Berdel, Wolfgang E., additional, Wörmann, Bernhard J., additional, Krug, Utz, additional, Braess, Jan, additional, Heußner, Pia, additional, Hiddemann, Wolfgang, additional, Spiekermann, Karsten, additional, and Metzeler, Klaus H., additional

Published
2022
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33. Secondary Neoplasms in AML Long-Term Survivors: Even More Cancer to Come?

Author

Moret, Anna Sophia, primary, Telzerow, Eva, additional, Sauerland, Maria Cristina, additional, Krauss, Simon M., additional, Rothenberg-Thurley, Maja, additional, Mumm, Friederike H.A., additional, Braess, Jan, additional, Wörmann, Bernhard J., additional, Krug, Utz, additional, Berdel, Wolfgang E., additional, Hiddemann, Wolfgang, additional, Spiekermann, Karsten, additional, Heußner, Pia, additional, Görlich, Dennis, additional, and Metzeler, Klaus H., additional

Published
2022
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34. Validation of the 2022 European Leukemianet Genetic Risk Stratification of Acute Myeloid Leukemia

Author

Rausch, Christian, primary, Rothenberg-Thurley, Maja, additional, Dufour, Annika Maria, additional, Schneider, Stephanie, additional, Gittinger, Hanna, additional, Sauerland, Maria Cristina, additional, Görlich, Dennis, additional, Krug, Utz, additional, Berdel, Wolfgang E., additional, Woermann, Bernhard Josef, additional, Hiddemann, Wolfgang, additional, Braess, Jan, additional, Spiekermann, Karsten, additional, Herold, Tobias, additional, and Metzeler, Klaus H., additional

Published
2022
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35. Life Satisfaction and Quality of Life in AML Long-Term Survivors: Primary Results of the AMLCG-Survivorship Study

Author

Telzerow, Eva, primary, Görlich, Dennis, additional, Sauerland, Maria Cristina, additional, Moret, Anna Sophia, additional, Rothenberg-Thurley, Maja, additional, Krauss, Simon M., additional, Mumm, Friederike H.A., additional, Amler, Susanne, additional, Berdel, Wolfgang E., additional, Wörmann, Bernhard J., additional, Krug, Utz, additional, Braess, Jan, additional, Heußner, Pia, additional, Hiddemann, Wolfgang, additional, Spiekermann, Karsten, additional, and Metzeler, Klaus H., additional

Published
2022
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36. Sex-Associated Differences in Frequencies and Outcome Prognostication of Recurrent Molecular Features in Adults with Acute Myeloid Leukemia (AML) (AMLCG, CALGB [Alliance])

Author

Ozga, Michael P., primary, Nicolet, Deedra, additional, Mrózek, Krzysztof, additional, Yilmaz, Selen, additional, Kohlschmidt, Jessica, additional, Larkin, Karilyn T., additional, Blachly, James S., additional, Oakes, Christopher C., additional, Buss, Jill, additional, Walker, Christopher J., additional, Orwick, Shelley, additional, Jurinovic, Vindi, additional, Rothenberg-Thurley, Maja, additional, Dufour, Annika Maria, additional, Schneider, Stephanie, additional, Sauerland, Maria Cristina, additional, Görlich, Dennis, additional, Krug, Utz, additional, Berdel, Wolfgang E., additional, Woermann, Bernhard Josef, additional, Hiddemann, Wolfgang, additional, Braess, Jan, additional, Subklewe, Marion, additional, Spiekermann, Karsten, additional, Carroll, Andrew J., additional, Blum, William G., additional, Powell, Bayard L., additional, Kolitz, Jonathan E., additional, Moore, Joseph O., additional, Mayer, Robert James, additional, Stone, Richard M., additional, Uy, Geoffrey L., additional, Stock, Wendy, additional, Metzeler, Klaus H., additional, Grimes, H. Leighton, additional, Byrd, John C., additional, Salomonis, Nathan, additional, Herold, Tobias, additional, Mims, Alice S., additional, and Eisfeld, Ann-Kathrin, additional

Published
2022
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37. Tandem Duplications of the UBTF gene in Adult AML: A Rare but Recurrent Alteration Associated with Myelodysplasia and Poor Outcome

Author

Georgi, Julia-Annabell, primary, Stasik, Sebastian, additional, Zukunft, Sven, additional, Hartwig, Marita, additional, Röllig, Christoph, additional, Oelschlaegel, Uta, additional, Krug, Utz, additional, Sauer, Tim, additional, Scholl, Sebastian, additional, Hochhaus, Andreas, additional, Brümmendorf, Tim H, additional, Naumann, Ralph, additional, Steffen, Björn, additional, Einsele, Hermann, additional, Schaich, Markus, additional, Burchert, Andreas, additional, Neubauer, Andreas, additional, Schaefer-Eckart, Kerstin, additional, Schliemann, Christoph, additional, Krause, Stefan W., additional, Haenel, Mathias, additional, Noppeney, Richard, additional, Kaiser, Ulrich, additional, Baldus, Claudia D., additional, Kaufmann, Martin, additional, Müller-Tidow, Carsten, additional, Platzbecker, Uwe, additional, Berdel, Wolfgang E., additional, Serve, Hubert, additional, Ehninger, Gerhard, additional, Bornhaeuser, Martin, additional, Schetelig, Johannes, additional, Kroschinsky, Frank P., additional, and Thiede, Christian, additional

Published
2022
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38. Germline SNPs previously implicated as prognostic biomarkers do not associate with outcomes in intensively treated AML

Author

Batcha, Aarif M. N., Buckup, Nele, Bamopoulos, Stefanos A., Jurinovic, Vindi, Rothenberg-Thurley, Maja, Gittinger, Hanna, Ksienzyk, Bianka, Dufour, Annika, Schneider, Stephanie, Kontro, Mika, Saad, Joseph, Heckmann, Caroline A., Sauerland, Cristina, Görlich, Dennis, Berdel, Wolfgang E., Wörmann, Bernhard J., Krug, Utz, Braess, Jan, Mansmann, Ulrich, Hiddemann, Wolfgang, Spiekermann, Karsten, Metzeler, Klaus H., and Herold, Tobias

Published
2023
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39. Germline SNPs previously implicated as prognostic biomarkers do not associate with outcomes in intensively treated AML

Author

Batcha, Aarif M.N., primary, Buckup, Nele, additional, Bamopoulos, Stefanos A, additional, Jurinovic, Vindi, additional, Rothenberg-Thurley, Maja, additional, Gittinger, Hanna, additional, Ksienzyk, Bianka, additional, Dufour, Annika, additional, Schneider, Stephanie, additional, Kontro, Mika, additional, Saad, Joseph, additional, Heckman, Caroline A., additional, Sauerland, Cristina M., additional, Görlich, Dennis, additional, Berdel, Wolfgang E., additional, Wörmann, Bernhard, additional, Krug, Utz, additional, Braess, Jan, additional, Mansmann, Ulrich Robert, additional, Hiddemann, Wolfgang, additional, Spiekermann, Karsten, additional, Metzeler, Klaus H, additional, and Herold, Tobias, additional

Published
2022
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40. Frontline therapy of acute promyelocytic leukemia: Randomized comparison of ATRA and intensified chemotherapy versus ATRA and anthracyclines

Author

Lengfelder, Eva, Görlich, Dennis, Nowak, Daniel, Spiekermann, Karsten, Haferlach, Claudia, Krug, Utz, Kreuzer, Karl‐Anton, Braess, Jan, Schliemann, Christoph, Lindemann, Hans‐Walter, Horst, Heinz A., Schiel, Xaver, Flasshove, Michael, Hecht, Anna, Schnittger, Susanne, Schneider, Stephanie, Wörmann, Bernhard, Hofmann, Wolf‐Karsten, Berdel, Wolfgang E., Bormann, Eike, Sauerland, Cristina, Büchner, Thomas, and Hiddemann, Wolfgang

Published
2018
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42. New Molecular Therapy Targets in Acute Myeloid Leukemia

Author

Krug, Utz, Serve, Hubert, Müller-Tidow, Carsten, Mesters, Rolf M., Steffen, Björn, Büchner, Thomas, Berdel, Wolfgang E., Schlag, P. M., editor, Senn, H. -J., editor, Kleihues, P., editor, Stiefel, F., editor, Groner, B., editor, Wallgren, A., editor, Rentchnik, P., editor, and Dietel, Manfred, editor

Published
2007
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43. Prediction of complete remission and survival in acute myeloid leukemia using supervised machine learning

Author

Eckardt, Jan-Niklas, primary, Röllig, Christoph, additional, Metzeler, Klaus, additional, Kramer, Michael, additional, Stasik, Sebastian, additional, Georgi, Julia-Annabell, additional, Heisig, Peter, additional, Spiekermann, Karsten, additional, Krug, Utz, additional, Braess, Jan, additional, Görlich, Dennis, additional, Sauerland, Cristina M., additional, Woermann, Bernhard, additional, Herold, Tobias, additional, Berdel, Wolfgang E., additional, Hiddemann, Wolfgang, additional, Kroschinsky, Frank, additional, Schetelig, Johannes, additional, Platzbecker, Uwe, additional, Müller-Tidow, Carsten, additional, Sauer, Tim, additional, Serve, Hubert, additional, Baldus, Claudia, additional, Schäfer-Eckart, Kerstin, additional, Kaufmann, Martin, additional, Krause, Stefan, additional, Hänel, Mathias, additional, Schliemann, Christoph, additional, Hanoun, Maher, additional, Thiede, Christian, additional, Bornhäuser, Martin, additional, Wendt, Karsten, additional, and Middeke, Jan Moritz, additional

Published
2022
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44. Differential impact of IDH1/2 mutational subclasses on outcome in adult AML: results from a large multicenter study

Author

Middeke, Jan Moritz, Metzeler, Klaus Hans, Röllig, Christoph, Krämer, Michael, Eckardt, Jan-Niklas, Stasik, Sebastian, Greif, Philipp, Spiekermann, Karsten, Rothenberg-Thurley, Maja, Krug, Utz, Braess, Jan, Krämer, Alwin, Hochhaus, Andreas, Brümmendorf, Tim Henrik, Naumann, Ralph, Steffen, Björn, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Görlich, Dennis, Sauerland, Cristina, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W., Hänel, Mathias, Frickhofen, Norbert, Noppeney, Richard, Kaiser, Ulrich, Kaufmann, Martin, Kunadt, Désirée, Wörmann, Bernhard, Sockel, Katja, Bonin, von Malte, Herold, Tobias, Müller-Tidow, Carsten, Platzbecker, Uwe, Berdel, Wolfgang E., Serve, Hubert, Baldus, Claudia, Ehninger, Gerhard, Schetelig, Johannes, Hiddemann, Wolfgang, Bornhäuser, Martin, Stölzel, Friedrich, Thiede, Christian, Middeke, Jan Moritz, Metzeler, Klaus Hans, Röllig, Christoph, Krämer, Michael, Eckardt, Jan-Niklas, Stasik, Sebastian, Greif, Philipp, Spiekermann, Karsten, Rothenberg-Thurley, Maja, Krug, Utz, Braess, Jan, Krämer, Alwin, Hochhaus, Andreas, Brümmendorf, Tim Henrik, Naumann, Ralph, Steffen, Björn, Einsele, Hermann, Schaich, Markus, Burchert, Andreas, Neubauer, Andreas, Görlich, Dennis, Sauerland, Cristina, Schäfer-Eckart, Kerstin, Schliemann, Christoph, Krause, Stefan W., Hänel, Mathias, Frickhofen, Norbert, Noppeney, Richard, Kaiser, Ulrich, Kaufmann, Martin, Kunadt, Désirée, Wörmann, Bernhard, Sockel, Katja, Bonin, von Malte, Herold, Tobias, Müller-Tidow, Carsten, Platzbecker, Uwe, Berdel, Wolfgang E., Serve, Hubert, Baldus, Claudia, Ehninger, Gerhard, Schetelig, Johannes, Hiddemann, Wolfgang, Bornhäuser, Martin, Stölzel, Friedrich, and Thiede, Christian

Abstract

Mutations of the isocitrate dehydrogenase-1 (IDH1) and IDH2 genes are among the most frequent alterations in acute myeloid leukemia (AML) and can be found in ∼20% of patients at diagnosis. Among 4930 patients (median age, 56 years; interquartile range, 45-66) with newly diagnosed, intensively treated AML, we identified IDH1 mutations in 423 (8.6%) and IDH2 mutations in 575 (11.7%). Overall, there were no differences in response rates or survival for patients with mutations in IDH1 or IDH2 compared with patients without mutated IDH1/2. However, distinct clinical and comutational phenotypes of the most common subtypes of IDH1/2 mutations could be associated with differences in outcome. IDH1-R132C was associated with increased age, lower white blood cell (WBC) count, less frequent comutation of NPM1 and FLT3 internal tandem mutation (ITD) as well as with lower rate of complete remission and a trend toward reduced overall survival (OS) compared with other IDH1 mutation variants and wild-type (WT) IDH1/2. In our analysis, IDH2-R172K was associated with significantly lower WBC count, more karyotype abnormalities, and less frequent comutations of NPM1 and/or FLT3-ITD. Among patients within the European LeukemiaNet 2017 intermediate- and adverse-risk groups, relapse-free survival and OS were significantly better for those with IDH2-R172K compared with WT IDH, providing evidence that AML with IDH2-R172K could be a distinct entity with a specific comutation pattern and favorable outcome. In summary, the presented data from a large cohort of patients with IDH1/2 mutated AML indicate novel and clinically relevant findings for the most common IDH mutation subtypes.

Published
2022

45. Genome-wide analysis of histone H3 acetylation patterns in AML identifies PRDX2 as an epigenetically silenced tumor suppressor gene

Author

Agrawal-Singh, Shuchi, Isken, Fabienne, Agelopoulos, Konstantin, Klein, Hans-Ulrich, Thoennissen, Nils H., Koehler, Gabriele, Hascher, Antje, Bäumer, Nicole, Berdel, Wolfgang E., Thiede, Christian, Ehninger, Gerhard, Becker, Anke, Schlenke, Peter, Wang, Yipeng, McClelland, Michael, Krug, Utz, Koschmieder, Steffen, Büchner, Thomas, Yu, Dae-Yeul, Singh, Shailendra Vikram, Hansen, Klaus, Serve, Hubert, Dugas, Martin, and Müller-Tidow, Carsten

Published
2012
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46. Additional file 1 of Impact of IDH1 and IDH2 mutational subgroups in AML patients after allogeneic stem cell transplantation

Author

Kunadt, Desiree, Stasik, Sebastian, Metzeler, Klaus H., Röllig, Christoph, Schliemann, Christoph, Greif, Philipp A., Spiekermann, Karsten, Rothenberg-Thurley, Maja, Krug, Utz, Braess, Jan, Krämer, Alwin, Hochhaus, Andreas, Scholl, Sebastian, Hilgendorf, Inken, Brümmendorf, Tim H., Jost, Edgar, Steffen, Björn, Bug, Gesine, Einsele, Hermann, Görlich, Dennis, Sauerland, Cristina, Schäfer-Eckart, Kerstin, Krause, Stefan W., Hänel, Mathias, Hanoun, Maher, Kaufmann, Martin, Wörmann, Bernhard, Kramer, Michael, Sockel, Katja, Egger-Heidrich, Katharina, Herold, Tobias, Ehninger, Gerhard, Burchert, Andreas, Platzbecker, Uwe, Berdel, Wolfgang E., Müller-Tidow, Carsten, Hiddemann, Wolfgang, Serve, Hubert, Stelljes, Matthias, Baldus, Claudia D., Neubauer, Andreas, Schetelig, Johannes, Thiede, Christian, Bornhäuser, Martin, Middeke, Jan M., and Stölzel, Friedrich

Abstract

Additional file 1: Table S1 Overview of the clinical trials the study patients were selected from. Figure S1 Forrest Plot of variables evaluated in univariate analysis. Multivariate Cox proportional hazard regression for (A) overall survival and (B) relapse-free survival.

Published
2022
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47. Quality of Life and Life Satisfaction in AML Long-Term Survivors: Primary Results of the AMLCG-Survivorship Study

Author

Telzerow, Eva, primary, Görlich, Dennis, additional, Rothenberg-Thurley, Maja, additional, Sauerland, Maria Cristina, additional, Moret, Anna Sophia, additional, Mumm, Friederike H. A., additional, Amler, Susanne, additional, Berdel, Wolfgang E., additional, Wörmann, Bernhard J., additional, Krug, Utz, additional, Braess, Jan, additional, Heußner, Pia, additional, Hiddemann, Wolfgang, additional, Spiekermann, Karsten, additional, and Metzeler, Klaus H., additional

Published
2021
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48. High Prevalence of CHF and Diabetes in AML Long-Term Survivors - a Patient Forever?

Author

Moret, Anna Sophia, primary, Telzerow, Eva, additional, Rothenberg-Thurley, Maja, additional, Sauerland, Maria Cristina, additional, Burgard, Elke, additional, Mumm, Friederike H. A., additional, Braess, Jan, additional, Wörmann, Bernhard J., additional, Krug, Utz, additional, Berdel, Wolfgang E., additional, Hiddemann, Wolfgang, additional, Spiekermann, Karsten, additional, Heußner, Pia, additional, Kraywinkel, Klaus, additional, Görlich, Dennis, additional, and Metzeler, Klaus H., additional

Published
2021
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49. Multi-Dimensional Analysis of Adult Acute Myeloid Leukemia (AML) Landscape Cross-Continents Reveals Age Associated Trends in Mutations and Outcomes

Author

Cusan, Monica, primary, Larkin, Karilyn, additional, Nicolet, Deedra, additional, Jurinovic, Vindi, additional, Mrózek, Krzysztof, additional, Batcha, Aarif M. N., additional, Rothenberg-Thurley, Maja, additional, Schneider, Stephanie, additional, Sauerland, Maria Cristina, additional, Görlich, Dennis, additional, Krug, Utz, additional, Berdel, Wolfgang E., additional, Woermann, Bernhard Josef, additional, Hiddemann, Wolfgang, additional, Braess, Jan, additional, Spiekermann, Karsten, additional, Kohlschmidt, Jessica, additional, Blachly, James S., additional, Mims, Alice S., additional, Walker, Christopher J., additional, Oakes, Christopher C., additional, Orwick, Shelley, additional, Carroll, Andrew J, additional, Blum, William, additional, Powell, Bayard L., additional, Kolitz, Jonathan E, additional, Moore, Joseph O., additional, Mayer, Robert James, additional, Larson, Richard A., additional, Stone, Richard M., additional, Byrd, John C., additional, Metzeler, Klaus H., additional, Herold, Tobias, additional, and Eisfeld, Ann-Kathrin, additional

Published
2021
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50. Prevalence and prognostic impact of allelic imbalances associated with leukemic transformation of Philadelphia chromosome–negative myeloproliferative neoplasms

Author

Thoennissen, Nils H., Krug, Utz O., Lee, Dhong Hyun Tony, Kawamata, Norihiko, Iwanski, Gabriela B., Lasho, Terra, Weiss, Tamara, Nowak, Daniel, Koren-Michowitz, Maya, Kato, Motohiro, Sanada, Masashi, Shih, Lee-Yung, Nagler, Arnon, Raynaud, Sophie D., Müller-Tidow, Carsten, Mesa, Ruben, Haferlach, Torsten, Gilliland, D. Gary, Tefferi, Ayalew, Ogawa, Seishi, and Koeffler, H. Phillip

Published
2010
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