32 results on '"Krueger RB"'
Search Results
2. Can Clinicians Use Dimensional Information to Make a Categorical Diagnosis of Paraphilic Disorders? An ICD-11 Field Study.
- Author
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Keeley JW, Briken P, Evans SC, First MB, Klein V, Krueger RB, Matsumoto C, Fresán A, Rebello TJ, Robles R, Sharan P, and Reed GM
- Subjects
- Diagnostic and Statistical Manual of Mental Disorders, Health Personnel, Humans, International Classification of Diseases, Paraphilic Disorders
- Abstract
Background: The diagnosis of paraphilic disorder is a complicated clinical judgment based on the integration of information from multiple dimensions to arrive at a categorical (present/absent) conclusion. The recent update of the guidelines for paraphilic disorders in ICD-11 presents an opportunity to investigate how mental health professionals use the diagnostic guidelines to arrive at a diagnosis which thereby can optimize the guidelines for clinical use., Aim: This study examined clinicians' ability to use the ICD-11 diagnostic guidelines for paraphilic disorders which contain multiple dimensions that must be simultaneously assessed to arrive at a diagnosis., Methods: The study investigated the ability of 1,263 international clinicians to identify the dimensions of paraphilic disorder in the context of written case vignettes that varied on a single dimension only., Outcomes: Participants provided diagnoses for the case vignettes along with dimensional ratings of the degree of presence of five dimensions of paraphilic disorder (arousal, consent, action, distress, and risk)., Results: Across a series of analyses, clinicians demonstrated a clear ability to recognize and appropriately integrate the dimensions of paraphilic disorders; however, there was some evidence that clinicians may over-diagnose non-pathological cases., Clinical Translation: Clinicians would likely benefit from targeted training on the ICD-11 definition of paraphilic disorder and should be cautious of over-diagnosing., Strengths and Limitations: This study represents a large international sample of health professionals and is the first to examine clinicians' ability to apply the ICD-11 diagnostic guidelines for paraphilic disorders. Important limitations include not generalizing to all clinicians and acknowledging that results may be different in direct clinical interactions vs written case vignettes., Conclusion: These results indicate that clinicians appear capable of interpreting and implementing the diagnostic guidelines for paraphilic disorders in ICD-11. Keeley JW, Briken P, Evans SC, et al. Can Clinicians Use Dimensional Information to Make a Categorical Diagnosis of Paraphilic Disorders? An ICD-11 Field Study. J Sex Med 2021;18:1592-1606., (Copyright © 2021 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.)
- Published
- 2021
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3. Topic: Professional competence in occupational therapy.
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Benfield A and Krueger RB
- Subjects
- Clinical Competence, Humans, Professional Competence, Occupational Therapy education
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- 2021
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4. Making Decision-Making Visible-Teaching the Process of Evaluating Interventions.
- Author
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Benfield A and Krueger RB
- Subjects
- Humans, Evidence-Based Practice, Health Occupations
- Abstract
Significant efforts in the past decades to teach evidence-based practice (EBP) implementation has emphasized increasing knowledge of EBP and developing interventions to support adoption to practice. These efforts have resulted in only limited sustained improvements in the daily use of evidence-based interventions in clinical practice in most health professions. Many new interventions with limited evidence of effectiveness are readily adopted each year-indicating openness to change is not the problem. The selection of an intervention is the outcome of an elaborate and complex cognitive process, which is shaped by how they represent the problem in their mind and is mostly invisible processes to others. Therefore, the complex thinking process that support appropriate adoption of interventions should be taught more explicitly. Making the process visible to clinicians increases the acquisition of the skills required to judiciously select one intervention over others. The purpose of this paper is to provide a review of the selection process and the critical analysis that is required to appropriately decide to trial or not trial new intervention strategies with patients.
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- 2021
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5. An organization- and category-level comparison of diagnostic requirements for mental disorders in ICD-11 and DSM-5.
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First MB, Gaebel W, Maj M, Stein DJ, Kogan CS, Saunders JB, Poznyak VB, Gureje O, Lewis-Fernández R, Maercker A, Brewin CR, Cloitre M, Claudino A, Pike KM, Baird G, Skuse D, Krueger RB, Briken P, Burke JD, Lochman JE, Evans SC, Woods DW, and Reed GM
- Abstract
In 2013, the American Psychiatric Association (APA) published the 5th edition of its Diagnostic and Statistical Manual of Mental Disorders (DSM-5). In 2019, the World Health Assembly approved the 11th revision of the International Classification of Diseases (ICD-11). It has often been suggested that the field would benefit from a single, unified classification of mental disorders, although the priorities and constituencies of the two sponsoring organizations are quite different. During the development of the ICD-11 and DSM-5, the World Health Organization (WHO) and the APA made efforts toward harmonizing the two systems, including the appointment of an ICD-DSM Harmonization Group. This paper evaluates the success of these harmonization efforts and provides a guide for practitioners, researchers and policy makers describing the differences between the two systems at both the organizational and the disorder level. The organization of the two classifications of mental disorders is substantially similar. There are nineteen ICD-11 disorder categories that do not appear in DSM-5, and seven DSM-5 disorder categories that do not appear in the ICD-11. We compared the Essential Features section of the ICD-11 Clinical Descriptions and Diagnostic Guidelines (CDDG) with the DSM-5 criteria sets for 103 diagnostic entities that appear in both systems. We rated 20 disorders (19.4%) as having major differences, 42 disorders (40.8%) as having minor definitional differences, 10 disorders (9.7%) as having minor differences due to greater degree of specification in DSM-5, and 31 disorders (30.1%) as essentially identical. Detailed descriptions of the major differences and some of the most important minor differences, with their rationale and related evidence, are provided. The ICD and DSM are now closer than at any time since the ICD-8 and DSM-II. Differences are largely based on the differing priorities and uses of the two diagnostic systems and on differing interpretations of the evidence. Substantively divergent approaches allow for empirical comparisons of validity and utility and can contribute to advances in the field., (© 2021 World Psychiatric Association.)
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- 2021
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6. Self-Reflection as a Support to Evidence-Based Practice: A Grounded Theory Exploration.
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Krueger RB, Sweetman MM, Martin M, and Cappaert TA
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- Female, Grounded Theory, Humans, Male, Surveys and Questionnaires, United States, Evidence-Based Practice, Occupational Therapists psychology, Self-Assessment
- Abstract
The purpose of this study was to explore how reflective practice is experienced by occupational therapists. Thirty participants were purposefully sampled to explore reflective practice experiences using a critical reflection inquiry model as a theoretical framework. Grounded theory using a constant comparative analysis method was used to analyze interview data. Three categories emerged: triggers to reflection, depth of reflection, and actions taken. The frequency of statements compared across survey groups showed that participants with high reflection behaviors made more critical reflections, used steps of the EBP cycle, and took actions to correct practice. Results inform practice in three ways: (1) practitioner experiences were analyzed through the complete reflective practice construct, (2) findings indicated that greater depth of reflective thinking promotes EBP use and actions taken to correct practice, and (3) narrative content analysis was found to be a credible method of assessing reflection within practice narratives, suggesting it as useful for education and promoting continuing competency.
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- 2020
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7. Occupational Therapists ' Implementation of Evidence-Based Practice: A Cross Sectional Survey.
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Krueger RB, Sweetman MM, Martin M, and Cappaert TA
- Subjects
- Cross-Sectional Studies, Female, Humans, Male, Surveys and Questionnaires, Attitude of Health Personnel, Evidence-Based Practice, Occupational Therapists
- Abstract
Evidence-based practice (EBP) implementation has been associated with quality health care outcomes, yet only a small proportion of occupational therapists implement EBP. We conducted a cross-sectional survey measuring EBP implementation, skill and knowledge, self-reflection behavior, and practice demographics to clarify implementation of EBP and factors acting as supports. A random sample of occupational therapists practicing in the U.S. was invited to participate; 578 surveys were included in the final analysis. Participants implemented EBP less than 1 time over the previous 8 weeks ; EBP use was highest in those with a doctorate ( p = .002) and high self-reflection behavior ( p = .001); EBP use was marginally higher in those with organizational support ( p = .008; p = .009), time for EBP ( p = .009), and access to full text articles ( p = .006). Further investigation of how reflective practice and levels of doctoral education support EBP use are recommended.
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- 2020
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8. Commentary on guidelines for the pharmacological treatment of paraphilic disorders.
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Krueger RB
- Subjects
- Humans, Biological Psychiatry, Paraphilic Disorders drug therapy, Sex Offenses
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- 2020
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9. Current Legal Situation for Patients with Paraphilic disorders and Implications of the ICD-11 for Paraphilic Disorders for Germany.
- Author
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Briken P, Boetticher A, Krueger RB, Kismödi E, and Reed GM
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- Adult, Child, Child Abuse, Sexual diagnosis, Child Abuse, Sexual legislation & jurisprudence, Child Abuse, Sexual psychology, Criminals legislation & jurisprudence, Fetishism, Psychiatric diagnosis, Fetishism, Psychiatric psychology, Germany, Humans, International Classification of Diseases, Masochism diagnosis, Masochism psychology, Paraphilic Disorders psychology, Sadism diagnosis, Sadism psychology, Sex Offenses legislation & jurisprudence, Sex Offenses psychology, Sexual Behavior psychology, Forensic Psychiatry legislation & jurisprudence, Paraphilic Disorders diagnosis
- Abstract
Introduction: Recently the guidelines for the diagnosis of paraphilic disorders in the International Classification of Diseases and Related Health Problems, Eleventh Revision (ICD-11), have been published., Aim: This article analyzes legal, regulatory, and policy issues relevant to the potential effects of the changes for the classification of paraphilic disorders in the ICD-11 in Germany., Methods: A forensic and a legal expert in Germany worked with other international experts to conduct this evaluation using an assessment guide provided by the World Health Organization., Main Outcome Measures: Possible effects of the changes for the classification of paraphilic disorders in the ICD-11 on forensic practice, health systems, adjudication of individuals who have committed a sexual offense, and the provision of treatment in Germany., Results: Results highlight the special situation of medical confidentiality in the German health system that facilitates the establishment of preventive networks for the treatment of pedophilic patients. The ICD-11 guidelines will help to clarify the boundary between pedophilic disorder and crimes of child sexual abuse. These will also establish a boundary with other paraphilic diagnostic concepts. We describe the central construct of criminal responsibility in the German legal system in relation to paraphilic disorders, the prominent role of expert witnesses, and the differences in the conceptualization of medical confidentiality within the health care system and within the legal system., Clinical Implications: The ICD-11 proposals for paraphilic disorders provide a clearer differentiation, as compared with ICD-10, between variants of normal sexual behavior and sexual behavior that involves a non-consenting person or entity. Particular patterns of sexual preference that are not of relevance to public health, the health care system, or the legal system, such as masochism and fetishism, will no longer be named psychiatric entities and will, therefore, be regarded as private behaviors and destigmatized., Strengths & Limitations: The assessment shows the specific legal situation in Germany for the treatment of paraphilic patients in a sexual medicine, psychiatric, and legal discourse. However, it was done only by a small number of experts., Conclusion: A conclusion of the analysis was that the more specific and narrower definitions in the ICD-11 diagnostic guidelines, compared with those in ICD-10, particularly for pedophilic disorder and coercive sexual sadism disorder, will result in a reduction in false-positive diagnoses. It is unlikely that significant unintended and negative consequences will occur as a result of implementing the ICD-11 guidelines for paraphilic disorders. Briken P, Boetticher A, Krueger RB, et al. Current Legal Situation for Patients with Paraphilic disorders and Implications of the ICD-11 for Paraphilic Disorders for Germany. J Sex Med 2019;16:1615-1622., (Copyright © 2019 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.)
- Published
- 2019
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10. From Atypical Sexual Interests to Paraphilic Disorders: The Planned ICD Revisions Related to Paraphilic Disorder.
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Briken P and Krueger RB
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- 2018
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11. Compulsive sexual behaviour disorder in the ICD-11.
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Kraus SW, Krueger RB, Briken P, First MB, Stein DJ, Kaplan MS, Voon V, Abdo CHN, Grant JE, Atalla E, and Reed GM
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- 2018
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12. Proposals for Paraphilic Disorders in the International Classification of Diseases and Related Health Problems, Eleventh Revision (ICD-11).
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Krueger RB, Reed GM, First MB, Marais A, Kismodi E, and Briken P
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- Fetishism, Psychiatric classification, Humans, Masochism classification, Sexuality, Transvestism classification, International Classification of Diseases, Paraphilic Disorders classification, Sexual Behavior classification
- Abstract
The World Health Organization is currently developing the 11th revision of the International Classifications of Diseases and Related Health Problems (ICD-11), with approval of the ICD-11 by the World Health Assembly anticipated in 2018. The Working Group on the Classification of Sexual Disorders and Sexual Health (WGSDSH) was created and charged with reviewing and making recommendations for categories related to sexuality that are contained in the chapter of Mental and Behavioural Disorders in ICD-10 (World Health Organization 1992a). Among these categories was the ICD-10 grouping F65, Disorders of sexual preference, which describes conditions now widely referred to as Paraphilic Disorders. This article reviews the evidence base, rationale, and recommendations for the proposed revisions in this area for ICD-11 and compares them with DSM-5. The WGSDSH recommended that the grouping, Disorders of sexual preference, be renamed to Paraphilic Disorders and be limited to disorders that involve sexual arousal patterns that focus on non-consenting others or are associated with substantial distress or direct risk of injury or death. Consistent with this framework, the WGSDSH also recommended that the ICD-10 categories of Fetishism, Fetishistic Transvestism, and Sadomasochism be removed from the classification and new categories of Coercive Sexual Sadism Disorder, Frotteuristic Disorder, Other Paraphilic Disorder Involving Non-Consenting Individuals, and Other Paraphilic Disorder Involving Solitary Behaviour or Consenting Individuals be added. The WGSDSH's proposals for Paraphilic Disorders in ICD-11 are based on the WHO's role as a global public health agency and the ICD's function as a public health reporting tool.
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- 2017
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13. Diagnosis of hypersexual or compulsive sexual behavior can be made using ICD-10 and DSM-5 despite rejection of this diagnosis by the American Psychiatric Association.
- Author
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Krueger RB
- Subjects
- Compulsive Behavior, Humans, Sexual Behavior, United States, International Classification of Diseases, Paraphilic Disorders
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- 2016
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14. Disorders related to sexuality and gender identity in the ICD-11: revising the ICD-10 classification based on current scientific evidence, best clinical practices, and human rights considerations.
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Reed GM, Drescher J, Krueger RB, Atalla E, Cochran SD, First MB, Cohen-Kettenis PT, Arango-de Montis I, Parish SJ, Cottler S, Briken P, and Saxena S
- Abstract
In the World Health Organization's forthcoming eleventh revision of the International Classification of Diseases and Related Health Problems (ICD-11), substantial changes have been proposed to the ICD-10 classification of mental and behavioural disorders related to sexuality and gender identity. These concern the following ICD-10 disorder groupings: F52 Sexual dysfunctions, not caused by organic disorder or disease; F64 Gender identity disorders; F65 Disorders of sexual preference; and F66 Psychological and behavioural disorders associated with sexual development and orientation. Changes have been proposed based on advances in research and clinical practice, and major shifts in social attitudes and in relevant policies, laws, and human rights standards. This paper describes the main recommended changes, the rationale and evidence considered, and important differences from the DSM-5. An integrated classification of sexual dysfunctions has been proposed for a new chapter on Conditions Related to Sexual Health, overcoming the mind/body separation that is inherent in ICD-10. Gender identity disorders in ICD-10 have been reconceptualized as Gender incongruence, and also proposed to be moved to the new chapter on sexual health. The proposed classification of Paraphilic disorders distinguishes between conditions that are relevant to public health and clinical psychopathology and those that merely reflect private behaviour. ICD-10 categories related to sexual orientation have been recommended for deletion from the ICD-11., (© 2016 World Psychiatric Association.)
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- 2016
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15. Paraphilic diagnoses in DSM-5.
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Krueger RB and Kaplan MS
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- Humans, Paraphilic Disorders classification, Diagnostic and Statistical Manual of Mental Disorders, Paraphilic Disorders diagnosis
- Abstract
Background: The DSM-5 has been under revision since 1999 and is scheduled for publication in 2013. This article will review the major proposed modifications of the Paraphilias., Method: The information reviewed was obtained from PubMed, PsychInfo, the DSM-5.org website and other sources and reviewed., Results: Pedohebephilia, Hypersexual Disorder and Paraphilic Coercive Disorder are new proposed diagnoses. Paraphilias have been assigned their own chapter in DSM- 5 and a distinction has been made between Paraphilias and Paraphilic Disorders. Victim numbers have been included in diagnosis of paraphilias that involve victims and remission and severity measures have been added to all paraphilias. Transvestic Disorder can apply to males or females, Fetishistic Disorder now includes partialism, and Sexual Masochism Disorder has Asphyxiophilia as a specifier., Limitations: This study is based on a literature review and influenced by the knowledge and biases of the authors., Conclusions: The Paraphilic Disorders Section of the DSM-5 represents a significant departure from DSMIV-TR.
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- 2012
16. Cognitive-behavioral treatment of the paraphilias.
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Kaplan MS and Krueger RB
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- Humans, Cognitive Behavioral Therapy methods, Paraphilic Disorders therapy
- Abstract
Background: Sexual offenders continue to occupy the public's attention; a significant proportion of this population is diagnosed with paraphilias. Cognitivebehavioral treatment has been the mainstay of treatment for sex offenders and for the paraphilias for the past three decades. This article will review the history of cognitivebehavioral therapy, its techniques, and its efficacy., Method: A literature review was conducted of PubMed and PsychInfo Databases., Results: A significant literature exists describing cognitive-behavioral therapy and presenting outcome studies and meta-analyses evaluating its efficacy., Limitations: This study is based on a literature review and influenced by the knowledge and biases of the authors., Conclusions: Cognitive-behavioral therapy is the most prominent therapy for sexual offenders. Although reports from individual programs and meta-analyses support its efficacy, overall, the strength of the evidence base supporting this therapy is weak and much more empirical research is needed.
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- 2012
17. Critical appraisals of the proposed DSM-5 paraphilia diagnoses.
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Krueger RB
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- Female, Humans, Male, Diagnostic and Statistical Manual of Mental Disorders, Paraphilic Disorders classification, Paraphilic Disorders diagnosis
- Published
- 2011
18. The DSM diagnostic criteria for sexual masochism.
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Krueger RB
- Subjects
- Humans, Diagnostic and Statistical Manual of Mental Disorders, Masochism diagnosis
- Abstract
I reviewed the empirical literature for 1900-2008 on the paraphilia of Sexual Masochism for the Sexual and Gender Identity Disorders Work Group for the forthcoming fifth edition of the Diagnostic and Statistical Manual of Mental Disorders. The results of this review were tabulated into a general summary of the criticisms relevant to the DSM diagnosis of Sexual Masochism, the assessment of Sexual Masochism utilizing the DSM in samples drawn from forensic populations, and the assessment of Sexual Masochism using the DSM in non-forensic populations. I concluded that the diagnosis of Sexual Masochism should be retained, that minimal modifications of the wording of this diagnosis were warranted, and that there was a need for the development of dimensional and structured diagnostic instruments. It should be noted that this summary reflects my original literature review. Subsequently, interactions with other members of the workgroup and advisors have resulted in modification of these initial suggestions.
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- 2010
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19. The DSM diagnostic criteria for sexual sadism.
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Krueger RB
- Subjects
- Humans, Diagnostic and Statistical Manual of Mental Disorders, Sadism diagnosis
- Abstract
I reviewed the empirical literature for 1900-2008 on the paraphilia of Sexual Sadism for the Sexual and Gender Identity Disorders Workgroup for the forthcoming fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM). The results of this review were tabulated into a general summary of the criticisms relevant to the DSM diagnosis of Sexual Sadism, the assessment of Sexual Sadism utilizing the DSM in samples drawn from forensic populations, and the assessment of Sexual Sadism using the DSM in non-forensic populations. I conclude that the diagnosis of Sexual Sadism should be retained, that minimal modifications of the wording of this diagnosis are warranted, and that there is a need for the development of dimensional and structured diagnostic instruments.
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- 2010
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20. Diagnosis, assessment, and treatment of hypersexuality.
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Kaplan MS and Krueger RB
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- Antidepressive Agents therapeutic use, Cognitive Behavioral Therapy, Comorbidity, Compulsive Behavior diagnosis, Compulsive Behavior therapy, Couples Therapy, Erotica, Fantasy, Female, Humans, Internet, Male, Masturbation diagnosis, Masturbation therapy, Paraphilic Disorders complications, Paraphilic Disorders epidemiology, Paraphilic Disorders psychology, Practice Guidelines as Topic, Psychological Theory, Sex Distribution, Sexology, Sexually Transmitted Diseases etiology, Telephone, Unsafe Sex, Paraphilic Disorders diagnosis, Paraphilic Disorders therapy
- Abstract
This article reviews the current evidence base for the diagnosis, assessment, and treatment of hypersexual conditions. Controversy concerning this diagnosis is discussed. Terminology and diagnostic criteria, as well as psychological, psychopharmacological, and other treatment approaches, are presented.
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- 2010
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21. Sexual and other axis I diagnoses of 60 males arrested for crimes against children involving the Internet.
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Krueger RB, Kaplan MS, and First MB
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- Adolescent, Adult, Child Abuse, Sexual statistics & numerical data, Diagnostic and Statistical Manual of Mental Disorders, Humans, Male, Middle Aged, Psychiatric Status Rating Scales, Young Adult, Child Abuse, Sexual psychology, Crime psychology, Internet statistics & numerical data, Paraphilic Disorders epidemiology, Paraphilic Disorders psychology
- Abstract
Objective: This study was conducted to describe Axis I sexual diagnoses of 60 males arrested for possession of child pornography obtained via the Internet and/or attempting to meet children via the Internet., Methods: Data was obtained from a chart review of evaluations conducted on 60 males referred for a psychosexual evaluation following an arrest for possession of child pornography and/or attempting to meet children. All crimes involved use of the Internet. Information obtained from the chart review was entered into SAS. All diagnoses were made according to the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition, Text Revision. Simple descriptive statistics were computed and cross tabulations were tested for significance using chi2 or Fisher's Exact test., Results: Of the total sample, 40% had at least one paraphilia. Thirty-one percent had a diagnosis of pedophilia and 18% of a paraphilia not otherwise specified (NOS). Thirty-three percent had a sexual disorder NOS, characterized by hypersexuality. Seventy percent of the total sample had an Axis I disorder that antedated and was judged to be contributory to the behavior leading to their arrest., Conclusions: This sample of men arrested for committing crimes against children and adolescents via the Internet has a high incidence of lifetime sexual and other psychopathology.
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- 2009
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22. Prescription of medroxyprogesterone acetate to a patient with pedophilia, resulting in Cushing's syndrome and adrenal insufficiency.
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Krueger RB, Hembree W, and Hill M
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- Adult, Aggression drug effects, Humans, Male, Pedophilia prevention & control, Pituitary-Adrenal System drug effects, Adrenal Insufficiency chemically induced, Contraceptive Agents, Male adverse effects, Cushing Syndrome chemically induced, Medroxyprogesterone Acetate adverse effects, Pedophilia drug therapy
- Abstract
This article provides a case report of a patient with pedophilia who was treated over a 4-year period with medroxyprogesterone acetate (MPA) at a dose of 300 mg/day and as a consequence developed Cushing's Syndrome and adrenal insufficiency, for which he was treated and from which he recovered. He also reported a hypersexual reaction to his own past cessation of MPA. Gonadotropin-releasing hormone agonists, which have a more benign side-effect profile than MPA, are suggested as an alternative to MPA.
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- 2006
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23. Treatment resources for the paraphilic and hypersexual disorders.
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Krueger RB and Kaplan MS
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- 2002
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24. The paraphilic and hypersexual disorders: an overview.
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Krueger RB and Kaplan MS
- Abstract
In this article, the first of a two-part series, the authors present reasons for considering the paraphilic and hypersexual disorders together and provide an overview of these disorders. The DSM-IV diagnostic criteria for paraphilias are reviewed, and proposed criteria for hypersexual disorders are presented. The question of whether the paraphilic and hypersexual disorders should be considered within the spectrum of obsessive-compulsive disorders is considered. The authors then review the epidemiology of these disorders, and discuss some implications of recent sexual predator legislation. The authors discuss the etiology of the paraphilias and hypersexual disorders, and consider the role of endocrinological function, findings from brain imaging and neuropsychological testing, findings from primate research, the monoamine hypothesis, the imprinting hypothesis, social learning theory, the concept of courtship disorder, the role of obsessive-compulsive elements, psychodynamic theories, and genetic factors. The phenomenology of the paraphilias and hypersexual disorders is discussed, including the tendency for multiple paraphilias to co-occur, the lack of a specific offender profile, the predominance of males among those with paraphilias, the incidence of a history of victimization in individuals with paraphilias and compulsive sexual disorders, the onset and course of both types of disorders, and the lack of internal motivation for change in individuals with paraphilias and hypersexual disorders. The authors then discuss disorders that commonly co-occur with paraphilias and compulsive sexual disorders, including mood disorders, substance abuse and dependence disorders, attention-deficit/hyperactivity disorder, anxiety and impulse control disorders, and personality disorders. The second article in the series will discuss the clinical assessment and the behavioral and psychopharmacological treatment of these disorders. A guide for clinicians and patients on where and how to find specialized clinicians and treatment resources in the United States will also be provided.
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- 2001
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25. Depot-leuprolide acetate for treatment of paraphilias: a report of twelve cases.
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Krueger RB and Kaplan MS
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- Adult, Androgen Antagonists adverse effects, Bone Resorption chemically induced, Delayed-Action Preparations, Follicle Stimulating Hormone metabolism, Follow-Up Studies, Humans, Leuprolide adverse effects, Luteinizing Hormone metabolism, Male, Middle Aged, Testosterone metabolism, Androgen Antagonists therapeutic use, Leuprolide therapeutic use, Paraphilic Disorders drug therapy
- Abstract
A new class of antiandrogen medications, gonadotropin-releasing hormone agonists, offers promise in the treatment of the paraphilias, with substantially less side effects than medroxyprogesterone acetate or cyproterone acetate. This paper reports the results of treatment using a depot suspension of leuprolide acetate on 12 patients with paraphilic disorders or with sexual disorders not otherwise specified to suppress or help these individuals control their deviant sexual behavior or impulses. The method involved uncontrolled observations of individuals treated with depot-leuprolide acetate for various lengths of time, from 6 months to 5 years, with the follow-up intervals ranging from 6 months to 6 years. Leuprolide acetate resulted in a significant suppression of deviant sexual interests and behavior as measured by self-report and was well tolerated. However, the three patients who were on long-term therapy developed bone demineralization, suggesting that this is a significant side effect of prolonged therapy. Leuprolide acetate shows promise as a treatment for the paraphilias.
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- 2001
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26. Disorders of sexual impulse control in neuropsychiatric conditions.
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Krueger RB and Kaplan MS
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- Androgen Antagonists adverse effects, Animals, Antipsychotic Agents therapeutic use, Brain Diseases physiopathology, Humans, Randomized Controlled Trials as Topic, Androgen Antagonists therapeutic use, Brain Diseases complications, Paraphilic Disorders drug therapy, Paraphilic Disorders etiology, Sexual Behavior drug effects
- Abstract
This article reviews hypersexuality in individuals with neuropsychiatric disorders and its psychopharmacologic treatment. A brief review of the neurology, neuroendocrinology, and neuropharmacology of sexual behavior is presented. Literature describing the occurrence and treatment of hypersexuality in individuals with neuropsychiatric disorders is reviewed along with literature which discusses the pharmacologic treatment of individuals with hypersexual disorders in nonneuropsychiatric populations. Finally, a clinical algorithm for approaching and treating such disorders in a neuropsychiatric population is presented., (Copyright 2000 Copyright by W.B. Saunders Company)
- Published
- 2000
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27. Report from the Committee on Sex Offenders: the Abel Assessment for Sexual Interest--a brief description.
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Krueger RB, Bradford JM, and Glancy GD
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- Humans, Male, Sexual Behavior physiology, Sexual Behavior psychology, Penile Erection physiology, Sex Offenses psychology
- Abstract
This article briefly reviews objective methods of assessing sexual interest and/or arousal and mentions some of the disadvantages of penile plethysmography. Literature that supports the use of viewing time as a measurement of sexual interest is reviewed. A detailed description of a new system of assessing sexual interest, called the Abel Assessment, which has both subjective and objective components, is presented. A critique of this assessment system is then offered.
- Published
- 1998
28. The significance of clinical EEG abnormalities in depressed patients treated with ECT.
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Malaspina D, Devanand DP, Krueger RB, Prudic J, and Sackeim HA
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- Cross-Over Studies, Depressive Disorder physiopathology, Female, Humans, Male, Middle Aged, Predictive Value of Tests, Depressive Disorder diagnosis, Depressive Disorder therapy, Electroconvulsive Therapy, Electroencephalography
- Abstract
Standard pretreatment clinical electroencephalograms (EEGs) were abnormal in 18.6% of 140 consecutive patients with Research Diagnostic Criteria (RDC) endogenous major depression. The patients were randomized to unilateral or bilateral and low- and high-dosage electroconvulsive therapy (ECT) conditions. Clinical features, short-term treatment response, and the rate and timing of relapse were contrasted in patients with normal and abnormal clinical EEG examinations. Psychotic depression was more common among abnormal EEG (61.5%) than normal EEG (38.9%) patients. Otherwise, the two groups were equivalent in a variety of demographic, clinical, and pharmacological variables. Patients with abnormal EEG findings tended to show a poorer rate of response to unilateral ECT, but a strong rate of response to bilateral ECT. Rates and timing of relapse were equivalent in the two groups. Other than the suggestion that bilateral ECT may be preferable in patients with clinical EEG abnormalities, little evidence was found that such abnormalities characterize discrete subgroups or have preductive utility with respect to ECT outcome.
- Published
- 1994
29. Acute cognitive effects of subconvulsive electrical stimulation.
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Prudic J, Sackeim HA, Devanand DP, Krueger RB, and Settembrino JM
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- Aged, Analysis of Variance, Behavior physiology, Cognition Disorders psychology, Depressive Disorder psychology, Depressive Disorder therapy, Electric Stimulation, Electroencephalography, Female, Humans, Male, Memory physiology, Middle Aged, Neuropsychological Tests, Orientation physiology, Speech, Cognition Disorders etiology, Electroconvulsive Therapy adverse effects
- Abstract
Empirical titration procedures increasingly are being used to estimate initial seizure threshold. These procedures involve the administration of subconvulsive electrical stimulation. There has yet to be evaluation of the impact of such stimulation on the acute cognitive consequences of electroconvulsive therapy. In two studies we randomized depressed patients to right unilateral or bilateral ECT, with stimulus intensity maintained just above seizure threshold throughout the treatment course. These low dosage treatment groups received one or more subconvulsive stimuli in approximately 40% of treatment sessions, with a grand mal seizure also elicited at each session. Extensive neuropsychological evaluation was conducted at each session. We contrasted treatment sessions in which generalized seizures were preceded by subconvulsive stimulation with treatment sessions in which a single convulsive stimulation was applied. Across a variety of neuropsychological measures, there were no adverse cognitive consequences of subconvulsive stimulation.
- Published
- 1994
30. Does ECT permanently alter seizure threshold?
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Krueger RB, Fama JM, Devanand DP, Prudic J, and Sackeim HA
- Subjects
- Adult, Aged, Electroencephalography, Female, Humans, Kindling, Neurologic physiology, Male, Middle Aged, Time Factors, Depressive Disorder therapy, Electroconvulsive Therapy adverse effects, Epilepsy physiopathology
- Abstract
Recent research has raised the possibility that electroconvulsive therapy (ECT) results in a persistent elevation of seizure threshold among males. In this study, seizure threshold, quantified by the method of limits procedure, was assessed at the first and last treatments of 148 consecutive depressed patients. Patients with and without a prior history of ECT did not differ in seizure threshold at the first treatment, seizure duration at the first treatment or averaged across all treatments, or in the magnitude of the seizure threshold increase over the ECT course. No evidence was obtained that history of ECT was associated with alterations of seizure threshold or seizure duration.
- Published
- 1993
- Full Text
- View/download PDF
31. In Reply: Stimulus Dosing Strategies and the Efficacy of Unilateral ECT.
- Author
-
Sackeim HA, Prudic J, Devanand DP, and Krueger RB
- Published
- 1992
32. Pharmacological treatment of the cognitive side effects of ECT: a review.
- Author
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Krueger RB, Sackeim HA, and Gamzu ER
- Subjects
- Animals, Cognition Disorders etiology, Cognition Disorders psychology, Humans, Cognition Disorders drug therapy, Electroconvulsive Therapy adverse effects
- Abstract
Electroconvulsive therapy (ECT) is an extremely effective treatment for a variety of psychiatric syndromes. However, it is frequently associated with transient cognitive side effects. Recent research has shown that these effects are sensitive to a number of treatment parameters, such as electrode placement and stimulus dosage, that the clinician may manipulate. However there have been relatively few efforts to determine if these cognitive side effects may be reduced or prevented by psychopharmacological intervention. In animals electroconvulsive shock (ECS) has been used frequently to screen for compounds which may improve cognition and memory. This paper reviews basic research studies on such compounds, as well as clinical trials in the treatment of various cognitive disorders. Studies using such compounds to reduce the cognitive side effects of ECT are exhaustively reviewed. The compounds that have been examined include: opioids, vasopressin, adrenocorticotropic hormone, other neuropeptides, cholinergic agents, nootropic agents, ergoloid mesylates, calcium-channel blockers, dexamethasone, thyroid hormone, and stimulants.
- Published
- 1992
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