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1,314 results on '"Kristiansen, G."'

3. Membranous NECTIN-4 expression in metastasis versus matched primary tumor more accurately predicts enfortumab vedotin response

Author

Büttner, T., primary, Zschäbitz, S., additional, Bolenz, C., additional, Zengerling, F., additional, Heers, H., additional, Nagy, D., additional, Toma, M., additional, Kristiansen, G., additional, Ellinger, J., additional, Ritter, M., additional, Hartmann, A., additional, Hölzel, M., additional, Eckstein, M., additional, and Klümper, N., additional

Published
2024
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4. Preclinical evidence for the use of anti-TROP-2 antibody-drug conjugate Sacituzumab govitecan in cerebral metastasized castration-resistant prostate cancer

Author

Weiten, R., primary, Niemann, M., additional, Below, E., additional, Friker, L.L., additional, Ralser, D.J., additional, Toma, M., additional, Kristiansen, G., additional, Hahn, O., additional, Zechel, S., additional, Grünwald, V., additional, Bald, T., additional, Siewert, J., additional, Pietsch, T., additional, Ritter, M., additional, Hölzel, M., additional, Eckstein, M., additional, Alajati, A., additional, Krausewitz, P., additional, and Klümper, N., additional

Published
2024
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5. Worry about prostate cancer and risk perception among middle-aged men: Results from the PROBASE trial

Author

Meissner, V.H., primary, Dinkel, A., additional, Kron, M., additional, Schiele, S., additional, Lakes, J., additional, Radtke, J.P., additional, Kuczyk, M., additional, Harke, N., additional, Debus, J., additional, Körber, S., additional, Antoch, G., additional, Schimmöller, L., additional, Kristiansen, G., additional, Krilaviciute, A., additional, Seibold, P., additional, Behrens, S., additional, Benner, A., additional, Arsov, C., additional, Hadaschik, B., additional, Becker, N., additional, Kaaks, R., additional, Albers, P., additional, Gschwend, J.E., additional, and Herkommer, K., additional

Published
2024
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10. Gliosarcoma with extensive extracranial metastatic spread and familial coincidence: A case report

Author

Friker, L.L., primary, Tzaridis, T., additional, Enkirch, S.J., additional, Lüders, C., additional, Hattingen, E., additional, Kristiansen, G., additional, Goschzik, T., additional, Waha, A., additional, Lütter, C., additional, Weller, J., additional, Herrlinger, U., additional, Pietsch, T., additional, Gessi, M., additional, Baumert, B.G., additional, and Gielen, G.H., additional

Published
2023
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13. Pre-adipocyte-driven NRG1 promotes resistance to FGFR3 inhibition in urothelial carcinoma

Author

Hosni, S, Kilian, V, Klümper, N, Gabbia, D, Winkler, A, Saponaro, M, Schmidt, D, J. Ralser, D, Corvino, D, Toma, M, Kristiansen, G, Bald, T, Eckstein, M, Wachten, D, Ritter, M, Hölzel, M, Geyer, M, de Martin, S, Alajati, A, Hosni, S, Kilian, V, Klümper, N, Gabbia, D, Winkler, A, Saponaro, M, Schmidt, D, J. Ralser, D, Corvino, D, Toma, M, Kristiansen, G, Bald, T, Eckstein, M, Wachten, D, Ritter, M, Hölzel, M, Geyer, M, de Martin, S, and Alajati, A

Published
2023

17. Longitudinale Untersuchung der membranären NECTIN-4 Expression liefert Hinweise auf primäre und sekundäre Resistenzmechanismen gegenüber Enfortumab-Vedotin in der Behandlung des metastasierten Urothelkarzinoms

Author

Büttner, T, Ralser, DJ, Nagy, D, Kristiansen, G, Adam, P, Manseck, A, Hartmann, A, Ellinger, J, Ritter, M, Hölzel, M, Eckstein, M, Klümper, N, Büttner, T, Ralser, DJ, Nagy, D, Kristiansen, G, Adam, P, Manseck, A, Hartmann, A, Ellinger, J, Ritter, M, Hölzel, M, Eckstein, M, and Klümper, N

Published
2023

23. Intermittent Hypoxia Contributes to the Lung Damage by Increased Oxidative Stress, Inflammation, and Disbalance in Protease/Antiprotease System

Author

Tuleta, I., Stockigt, F., Juergens, U. R., Pizarro, C., Schrickel, J. W., Kristiansen, G., Nickenig, G., and Skowasch, D.

Subjects
Anoxia -- Complications and side effects -- Research, Oxidative stress -- Complications and side effects -- Research, Lung diseases -- Risk factors -- Development and progression -- Research, Health
Abstract

Introduction Intermittent hypoxia as a surrogate of obstructive sleep apnea is associated with different cardiovascular complications. However, the effects of intermittent hypoxia on the lung tissue are less known. Therefore, the aim of our present study was to investigate if intermittent hypoxia may influence oxidative stress, inflammation, and protease/antiprotease system in the lung. Additionally, potential protective properties of anti-inflammatory and anti-oxidative drugs have been evaluated. Methods 32 mice were divided into four groups: (1) intermittent hypoxia, (2) intermittent hypoxia with infliximab, (3) intermittent hypoxia with l-glutathione, and (4) normoxia. After 4 weeks, lungs and blood were collected. Levels of reactive oxygen species in the lung were calculated by L-O12-enhanced chemiluminescence. CD68-positive lung macrophages were detected by immunofluorescence. Concentrations of elastase and desmosine in lung and of alpha-1-antitrypsin in blood were calculated by means of enzyme-linked immunosorbent assay. Results Compared to a control, intermittent hypoxia augmented the release of free oxygen radicals, expression of CD68+ macrophages, and concentration of elastase in the lung tissue. Despite increased blood levels of protective alpha-1-antitrypsin, concentrations of desmosine-degradation product of elastin were higher versus control. The application of anti-inflammatory infliximab und anti-oxidative l-glutathione prevented at least partly the above-observed hypoxia-associated changes. Conclusions Intermittent hypoxia contributes to the lung damage by increased oxidative stress, inflammation, and disbalance in protease/antiprotease system. Infliximab and l-glutathione may prevent adverse hypoxia-induced lung alternations., Author(s): I. Tuleta[sup.1] , F. Stockigt[sup.1] , U. R. Juergens[sup.1] , C. Pizarro[sup.1] , J. W. Schrickel[sup.1] , G. Kristiansen[sup.2] , G. Nickenig[sup.1] , D. Skowasch[sup.1] Author Affiliations: (1) Department [...]

Published
2016
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27. Categoriality in the English gerund system

Author

Maekelberghe, C., Fonteyn, L., Heyvaert, L., Kristiansen, G., Franco, K., Pascale, S. de, Rosseel, L., Zhang, W., Kristiansen, G., Franco, K., Pascale, S. de, Rosseel, L., and Zhang, W.

Subjects
Competition, Gerund, English Linguistics, Cognitive Linguistics
Published
2021

30. Die frühe longitudinale CRP-Kinetik sagt das Ansprechen gegenüber Anti-PD-(L)1-Immuncheckpoint-Blockade im metastasiertem Urothelkarzinom voraus

Author

Klümper, N., Sikic, D., Saal, J., Büttner, T., Goldschmidt, F., Jarczyk, J., Becker, P., Zeuschner, P., Weinke, M., Kalogirou, C., Breyer, J., Burger, M., Nuhn, P., Tully, K., Roghmann, F., Bolenz, C., Zengerling, F., Wirtz, R., Muders, M., Kristiansen, G., Bald, T., Ellinger, J., Wullich, B., Hölzel, M., Hartmann, A., Erben, P., Ritter, M., and Eckstein, M.

Subjects
ddc: 610, Medicine and health
Abstract

Einleitung: Es gibt weiterhin keinen robusten prädiktiven Biomarker zur Vorhersage des Ansprechens gegenüber Immuncheckpoint-Blockade (ICB) beim metastasierten Urothelkarzinom (mUC.) Die frühe Kinetik des C-reaktiven Proteins (CRP) nach Einleitung der ICB und insbesondere das kürzlich [zum vollständigen Text gelangen Sie über die oben angegebene URL]

Published
2022

36. Postoperative SHOX2-Hypermethylierung in zirkulierender zellfreier DNA im Blut ist mit einem verk��rzten metastasenfreien und krebsspezifischen ��berleben bei Patienten mit Nierenzellkarzinom assoziiert

Author

Büttner, T, Zarbl, R, Ellinger, J, Strieth, S, Kristiansen, G, Ritter, M, Dietrich, D, and Klümper, N

Subjects
ddc: 610, Medicine and health
Abstract

Einleitung: F��r die adjuvante Immuncheckpoint-Inhibition beim Nierenzellkarzinom (RCC) mit dem anti-PD-1-Inhibitor Pembrolizumab konnte erstmalig ein Vorteil im krankheitsfreien ��berleben nach Nephrektomie gezeigt werden (KEYNOTE-564). Es gilt nun, Subgruppen zu identifizieren die im Besonderen [zum vollst��ndigen Text gelangen Sie ��ber die oben angegebene URL]

Published
2022
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37. Die Rolle der systematischen Prostatastanzbiopsie im Rahmen der prim��ren mpMRT/Ultraschall-Fusionsbiopsie ��� Ergebnisse eines High-Volume Centers

Author

Krausewitz, P, Klümper, N, Stein, J, Attenberger, U, Luetkens, J, Kristiansen, G, Ellinger, J, and Ritter, M

Subjects
ddc: 610, Medicine and health
Abstract

Fragestellung: Die Durchf��hrung multiparametrischer Magnetresonanztomographien (mpMRT) vor Prostatabiopsien verbessert die Detektionsrate (CDR) von Prostatakarzinomen (PCA). Wir verglichen die Tumordetektionsrate der gezielten (TB) und systematischen (SB) mpMRT/Ultraschall-Fusionsbiopsien [zum vollst��ndigen Text gelangen Sie ��ber die oben angegebene URL]

Published
2022
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38. DEPROMP-Studie: Prospektive Evaluation der Detektionsrate klinisch signifikanter Prostatakarzinome in der Primärdiagnostik durch Kombination von PSMA-PET/CT- und multiparametrischer MRT-Fusionsstanzbiopsie

Author

Krausewitz, P, Gärtner, F, Bundschuh, R, Essler, M, Attenberger, U, Luetkens, J, Muders, M, Kristiansen, G, Hauser, S, Ellinger, J, Ritter, M, Krausewitz, P, Gärtner, F, Bundschuh, R, Essler, M, Attenberger, U, Luetkens, J, Muders, M, Kristiansen, G, Hauser, S, Ellinger, J, and Ritter, M

Published
2022

39. Die frühe C-reaktive-Protein Kinetik sagt das Ansprechen gegenüber Anti-PD-(L)1-Immuncheckpoint-Blockade im metastasierten Urothelkarzinom voraus

Author

Klümper, N, Sikic, D, Saal, J, Büttner, T, Goldschmidt, F, Jarczyk, J, Becker, P, Zeuschner, P, Weinke, M, Kalogirou, C, Breyer, J, Burger, M, Nuhn, P, Tully, K, Roghmann, F, Bolenz, C, Zengerling, F, Wirtz, RM, Muders, M, Kristiansen, G, Ellinger, J, Wullich, B, Hölzel, M, Hartmann, A, Erben, P, Ritter, M, Eckstein, M, Klümper, N, Sikic, D, Saal, J, Büttner, T, Goldschmidt, F, Jarczyk, J, Becker, P, Zeuschner, P, Weinke, M, Kalogirou, C, Breyer, J, Burger, M, Nuhn, P, Tully, K, Roghmann, F, Bolenz, C, Zengerling, F, Wirtz, RM, Muders, M, Kristiansen, G, Ellinger, J, Wullich, B, Hölzel, M, Hartmann, A, Erben, P, Ritter, M, and Eckstein, M

Published
2022

41. Die frühe longitudinale CRP-Kinetik sagt das Ansprechen gegenüber Anti-PD-(L)1-Immuncheckpoint-Blockade im metastasiertem Urothelkarzinom voraus

Author

Klümper, N, Sikic, D, Saal, J, Büttner, T, Goldschmidt, F, Jarczyk, J, Becker, P, Zeuschner, P, Weinke, M, Kalogirou, C, Breyer, J, Burger, M, Nuhn, P, Tully, K, Roghmann, F, Bolenz, C, Zengerling, F, Wirtz, R, Muders, M, Kristiansen, G, Bald, T, Ellinger, J, Wullich, B, Hölzel, M, Hartmann, A, Erben, P, Ritter, M, Eckstein, M, Klümper, N, Sikic, D, Saal, J, Büttner, T, Goldschmidt, F, Jarczyk, J, Becker, P, Zeuschner, P, Weinke, M, Kalogirou, C, Breyer, J, Burger, M, Nuhn, P, Tully, K, Roghmann, F, Bolenz, C, Zengerling, F, Wirtz, R, Muders, M, Kristiansen, G, Bald, T, Ellinger, J, Wullich, B, Hölzel, M, Hartmann, A, Erben, P, Ritter, M, and Eckstein, M

Published
2022

42. Die molekulare und epigenetische Funktion des Signalmoleküls CD24 in Keimzelltumoren und dessen therapeutischer Angriff über Antikörper und NK-CAR-Zellen

Author

Skowron, M, Becker, T, Kurz, L, Jostes, S, Bremmer, F, Fronhoffs, F, Funke, K, Wakileh, G, Müller, M, Burmeister, A, Lenz, T, Stefanski, A, Stühler, K, Petzsch, P, Köhrer, K, Altevogt, P, Albers, P, Kristiansen, G, Schorle, H, Nettersheim, D, Skowron, M, Becker, T, Kurz, L, Jostes, S, Bremmer, F, Fronhoffs, F, Funke, K, Wakileh, G, Müller, M, Burmeister, A, Lenz, T, Stefanski, A, Stühler, K, Petzsch, P, Köhrer, K, Altevogt, P, Albers, P, Kristiansen, G, Schorle, H, and Nettersheim, D

Published
2022

43. Genexpressionsanalyse zur Prognosevorhersage beim duktalen Pankreaskarzinom

Author

Grützmann, R., Wente, M., Niedergethmann, M., Friess, H., Bahra, M., Rümmele, P., Kristiansen, G., Winter, Ch., Saeger, H. D., Pilarsky, Ch., Buhr, H. J., editor, Hölscher, A., editor, Izbicki, J. R., editor, Jauch, K. W., editor, Post, S., editor, Allgayer, H., editor, Bartsch, D. K., editor, Fries, H., editor, Ghadimi, B. M., editor, Habermann, J. K., editor, Kalthoff, H., editor, Schackert, H. K., editor, Bruns, C. J., editor, Duda, D. N., editor, Fändrich, F., editor, Heberer, M., editor, Nüssler, A. K., editor, Stark, G. B., editor, Brückner, U. B., editor, Ertel, W., editor, Faist, E., editor, Heidecke, C. D., editor, Kalff, J. C., editor, Menger, M. D., editor, Schade, U. F., editor, Vollmar, B., editor, Bechstein, W. O., editor, Klar, E., editor, Klempnauer, J., editor, Minor, T., editor, Neuhaus, P., editor, Schmidt, J., editor, Langer, S., editor, Laschke, M. W., editor, Machens, H. G., editor, Steinau, H. U., editor, Südkamp, N., editor, Vogt, P., editor, Berger, D., editor, Klinge, U., editor, Schachtrupp, A., editor, Schilling, M. K., editor, Schumpelick, V., editor, Altendorf-Hofmann, A., editor, Bollschweiler, E., editor, Bruch, H. -P., editor, Lehnert, T., editor, Lorenz, W., editor, Neugebauer, E., editor, Ohmann, C., editor, Seiler, C. M., editor, Becker, H., editor, Betzler, M., editor, Bittner, R., editor, Broelsch, C., editor, Büchler, M. W., editor, Bumm, R., editor, Dralle, H., editor, Friess, H., editor, Frilling, A., editor, Germer, C. T., editor, Hopt, U., editor, Jonas, S., editor, Jost, J., editor, Markus, B., editor, Raab, H. R., editor, Reith, H. B., editor, Schlag, P. M., editor, Teichmann, W., editor, Uhl, W., editor, Wenisch, H., editor, and Zornig, C., editor

Published
2009
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47. Bewirkt der hoch-selektive Matrix-Metalloproteinase-Inhibitor RO 28-2653 über eine Reduktion der Matrix-Metalloproteinasen −2 und −9 eine Verminderung des Tumorwachstums und der Lebermetastasierung beim duktalen Pankreaskarzinom im Syrischen Hamster?

Author

Gregor, Jan I., Heukamp, I., Kilian, M., Hanel, M., Kristiansen, G., Schimke, I., Walz, M. K., Jacobi, C. A., Wenger, F. A., Bruch, H. P., editor, Büchler, M. W., editor, Buhr, H. J., editor, Hohenberger, W., editor, Klar, E., editor, Post, S., editor, Schilling, M., editor, Schumpelick, V., editor, Siewert, J. R., editor, Thiede, A., editor, Becker, H., editor, Bittner, R., editor, Függer, R., editor, Köckerling, F., editor, Saeger, H. D., editor, Zornig, C., editor, Hölscher, A., editor, Izbicki, J. R., editor, Jauch, K. W., editor, Senninger, N., editor, Allgayer, H., editor, Bruns, C. J., editor, Celik, I., editor, Fries, H., editor, Kalthoff, H., editor, Schackert, H. K., editor, Brückner, U. B., editor, Ertel, W., editor, Faist, E., editor, Holzheimer, R. G., editor, Holzmann, B., editor, Schade, U. F., editor, Vollmar, B., editor, Heidecke, C. D., editor, Menger, M. D., editor, Neugebauer, E., editor, Spiegel, H. U., editor, Germann, G., editor, Haas, N., editor, Langer, S., editor, Machens, H. G., editor, Stark, G. B., editor, Steinau, H. U., editor, Haverich, A., editor, Heberer, M., editor, Fitze, G., editor, Roth, H., editor, von Schweinitz, D., editor, Waag, K. L., editor, Altendorf-Hofmann, A., editor, Lehnert, T., editor, Lorenz, W., editor, Ohmann, C., editor, Bechstein, W. O., editor, Broelsch, C., editor, Hopt, U., editor, Klempnauer, J., editor, Fändrich, F., editor, Markus, B., editor, Minor, T., editor, Neuhaus, P., editor, Wonigeit, K., editor, Dralle, H., editor, Goretzki, P. E., editor, Rothmund, M., editor, Bühren, V., editor, Josten, C., editor, Muhr, G., editor, Nast-Kolb, D., editor, Stürmer, K. M., editor, Trentz, O., editor, Brunkwall, J., editor, Sandmann, W., editor, Schmitz-Rixen, T., editor, Storck, M., editor, Branscheid, D., editor, Dienemann, H., editor, Hirner, A., editor, Passlick, B., editor, Toomes, H., editor, Beyersdorf, F., editor, Hetzer, R., editor, Schäfers, H. J., editor, Steinsträßer, L., editor, Vogt, P., editor, Arbogast, R., editor, and Bauer, H., editor

Published
2008
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48. Deciphering the mechanistic role of PBRM1 loss in inflammatory and morphogenic signalling within the tumour microenvironment of clear cell renal cell carcinoma

Author

Klümper, N., primary, Linxweiler, J., additional, Tran, K.N., additional, Zeuschner, P., additional, Ng, S., additional, Leonardelli, S., additional, Albrecht, J., additional, Rieck, S., additional, Bamarni, A., additional, Lindenberg, T.T., additional, Odermatt, B., additional, Kristiansen, G., additional, Ritter, M., additional, Ellinger, J., additional, Alajati, A., additional, Fleischmann, B.K., additional, Junker, K., additional, Toma, M., additional, and Hölzel, M., additional

Published
2022
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49. The molecular and epigenetic function of the signaling molecule CD24 in germ cell tumors and its suitability as a therapeutic target using antibodies and NK-CAR cells

Author

Skowron, M.A., primary, Thomas, D.J., additional, Becker, T.K., additional, Kurz, L., additional, Jostes, S., additional, Bremmer, F., additional, Fronhoffs, F., additional, Funke, K., additional, Wakileh, G.A., additional, Müller, M.R., additional, Burmeister, A., additional, Lenz, T., additional, Stefanski, A., additional, Stühler, K., additional, Petzsch, P., additional, Köhrer, K., additional, Altevogt, P., additional, Albers, P., additional, Kristiansen, G., additional, Schorle, H., additional, and Nettersheim, D., additional

Published
2022
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50. Complexity in complementation

Author

Cuyckens, H., Fonteyn, L., Petré, P., Kristiansen, G., Franco, K., Pascale, S. de, Rosseel, L., and Zhang, W.

Subjects
Language Change, Idiolect, Verb Complementation, Syntax
Published
2021

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