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Byline: Mangala. Murthy, Bhaskar. Krishnamurthy Introduction : Nevirapine administered as a single dose each to the mother and child within 72 h after birth is used to prevent vertical transmission [...]

Byline: Mangala. Murthy, Bhaskar. Krishnamurthy Sir, Misleading drug advertising encourages drug consumerism rather than rational use of drugs. To add to the problem, developing countries lack a strong system to [...]

Byline: Mangala. Murthy, Bhaskar. Krishnamurthy Albeit uncommon occurrence, irritant contact dermatitis induced by povidone iodine can be an unfortunate adverse reaction complicating its use as an antiseptic. We hereby present [...]

Hypersensitivity reactions are commonly encountered with drugs such as beta lactams, sulphonamides, allopurinol etc., Corticosteroids are frequently employed in the treatment of drug induced allergic reactions. Therefore, it is highly unlikely that a corticosteroid itself may cause such a reaction as an adverse effect. We had encountered a rare case of hypersensitivity reaction with inhalational budesonide in an eight-year-old boy. The patient developed maculopapular rashes over the back, buttocks and legs accompanied with pruritus within four hours of administration of the first dose. The reaction subsided within two days on withdrawal of the drug and treatment with oral fexofenadine. Re-introduction of budesonide by the same route after a month resulted in appearance of similar reaction. Both the parents of the patient were known cases of allergic rhinitis suggesting allergic pre-disposition in the family. Causality analysis using WHO-UMC scale suggested certain association of this allergic reaction with inhaled budesonide. [ABSTRACT FROM AUTHOR]