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This paper provides a descriptive review of the impacts of the global financial crisis on the Indian economy. While examining the growth in the gross domestic product (GDP), fiscal deficit, exports, imports, Wholesale Price Index (WPI) inflation, and the foreign exchange rates (FX), we find that the GDP has been severely impacted during the crisis period, especially during 2008-09. While the fiscal deficit continuously increased during 2008-09 and 2009-10, the exports and imports declined considerably. The WPI inflation followed a downward trend, and the rupee depreciated by approximately 20 percent during 2008. During 2008-09, the agricultural and industrial growth significantly declined, but the service sector sustained itself. The findings also reveal that the policy initiatives by the Indian government and those by the Reserve Bank of India safeguarded the Indian economy to a large extent.

This work reports the synthesis of semiconductor selenium nanoparticles/micro-rods (Se-NP/MRs) using the bio-fabrication approach and studies its photocatalytic activity under natural sunlight irradiation. Cabbage leaf extract was used as a reducing agent to fabricate Se-NP/MRs. X-ray diffraction patterns shown the crystalline structure with a crystallite size of 28.17 nm, conferring to planes of hexagonal structure. A characteristic sharp resonance peak in Raman spectra at 235 cm−1 endorsed to the Se – Se bond of crystalline Se-NP/MRs. The prominent peak in the FTIR spectra at 621 cm−1 supported the formation of Se-NP/MRs. Scanning electron micrograph revealed a nearly spherical shape with irregular layers in the 35‒95 nm size range. In contrast, the dimension of the micro-rods was observed to be ~ 10 µm in length and 2.5 µm in diameter. The bandgap energy of Se-NP/MRs was analysed to be 2.14 eV using the Tauc plot. The exciting photocatalytic performance of the bio-fabricated Se-NP/MRs revealed that the methylene blue degradation was ~ 86% in 40 min and ~ 97% in 140 min. Kinetic analysis shows that the pseudo-second-order correlation coefficient is well fitted compared to the pseudo-first-order. Therefore, this work opens the door to further exploration of nano-materials/composites with mixed nanoparticles/micro-rods morphology for sustainable applications in the removal of various textile and industrial contaminants.

Algae biomass has been recognized as one of the most suitable, efficient, and reliable feedstocks for bio-oil production. Among the different processes, hydrothermal liquefaction (HTL) is emerging as an effective technology for the valorization of various types of wet or dry biomass. Several factors, including temperature, retention time, and catalyst, significantly influence the overall efficiency of HTL products. The temperature ∼280 ± 40 °C is reported to be the most suitable range to achieve maximum bio-oil. Both homogeneous and heterogeneous catalysts have been used to improve bio-oil yield. For several advantages, heterogeneous catalysts are the preferred choice due to improved bio-oil generation, easy recovery, and uses. The eco-friendly approach and the reduction of heteroatoms in bio-oils make heterogeneous catalysts an ideal choice to be fortified. Alkaline catalysts have been considered most suitable to improve HTL yield. Variations in temperature and catalysts not only influence the yield of the bio-oil but also influence the characteristics of the bio-oil (e.g. high heating value, oxidative stability, gaseous emission, etc.) simultaneously. This review reveals interesting features including HTL temperature vs. yield, catalysts vs. yield, and the effect of wet and dry biomass on bio-oil properties, and finally, observations, remarks/limitations are presented for future studies.

Microalgae and the associated biomass have been advocated for various eco-friendly applications. Although, microalgae are a good source of biofuels, metabolites, and value-added products, their commercial cultivation suffers from limited biomass yield due to inefficient photosynthetic efficiency. Minimizing the light-harvesting antenna size of the photosystems has been recognized as an effective mechanism to enhance photosynthetic efficiency and overall biomass productivity in microalgal cultures. Several strategies including mutagenesis, through UV radiations and chemical mutagenesis, genetic engineering, and DNA insertional mutagenesis have been employed to obtain mutant strains possessing a regulated antenna with a regulated limited number of light-harvesting molecules. However, there are still a number of challenges associated with antenna mutants that need to be addressed. This review highlights the recent developments in truncated antenna mutants of microalgae, aiming to increase the photosynthetic efficiency and biomass productivity of the respective cultures.

This study presents the use of a novel photocavity reactor in order to intensify the growth rate, biomass and lipid productivity in microalgae. The reactor offers an aseptic approach for better control on growth rate in microalgae.The Absorption Factor (AF), Attenuation Factor (AtF), Modified Fluence Rate (MFR) and water factor of the photo reactor were recorded to be 1.581, 0.267, 0.347 mW/cm2 and 2.072 respectively. The maximum growth rate recorded was 310 mg L−1 inphotocavity reactor. The results clearly indicate that using the stainless steel visible photoreactor can lead to a significant increase in the growth rate (43.3%), productivity of biomass (27-33%) and lipid content (6-8%) in comparison to microalgae cultivated in glass conical flasks (control). COD, total nitrogen, phosphate and bacterial load (colony-forming unit- CFU) were determined in this study. A decrease in COD (180 to 19 mg/l) and CFU (57×109 to 5×101) of wastewater was also recorded in this study.

The fabrication of the inorganic metal oxide nanoparticles by using extract of the different part of the plant was gaining an overwhelming response from the last few years. Magnetic iron oxide nano...

The development of nontoxic bio-waste based catalyst for efficient recycling of textile dye wastewater to potable water is paramount to support a sustainable environment. This research work investi...

Utilization of harmful algal blooms (HABs) for the cultivation of oleaginous microorganisms can provide dual benefits of mitigating the toxicity from the aquatic reservoirs and generation of copious media for biodiesel production. In the present investigation, microwave-assisted dilute alkali-freeze pretreatment was optimized to develop a low-cost growth medium from HAB dried biomass. The electron micrographs along with the elemental analysis confirmed the efficient breakage of HABs after the microwave-assisted hydrolysis treatment as compared with the acid hydrolysis. Moreover, the sugar analysis revealed ~ 46% higher carbohydrate content in microwave-assisted hydrolysate as compared with acid hydrolysate. The microwave-assisted hydrolysate and conventional dilute acid hydrolysate were then used to cultivate microalga (Chlorella minutissima) and yeast (Trichosporon cutaneum) for biomass and lipid accumulation and compared to artificial media. Microalga showed ~ 1.3- and 2-fold higher dry cell weight (DCW) and lipid content, respectively, while the yeast growth increased by ~ 27% with lipid content of 30%. The fatty acid profiles and biodiesel properties were also amenable to the international biodiesel standards. Hence, the present study provides a proof-of-concept of utilizing HAB hydrolysate for culturing oleaginous microorganisms for potential biodiesel production.

The present paper reports the green synthesis of TiO2 NPs to evaluate its photocatalytic activity. In this synthesis we use Aegle marmelos leaf extract as reducing and stabilizing agent. The TiO2 nanoparticles were characterized by using various advance analytical tools. The FTIR analysis revels the presence of different functional group present on the surface of the fabricated nanoparticles. The result of SEM analysis indicated that the prepared nanoparticles were almost spherical in nature and particles are in agglomerated state with bunch size less than 150 nm. The X-ray analysis of our synthesized nanoparticles clearly indicated that the particles are exit in anatase phase. Photocatalytic degradation studies of our nanoparticles were also evaluated against the most common nitroimidazole derivative drug ornidazole (ODZ) and the result of this study provide a good alternative path to remove the ODZ contaminants from waste water. The photocatalytic degradation of selected drug follow pseudo-first order reaction.

This study evaluated the IC50 value of cadmium against four different strains of microalgae. Chlorella sorokiniana was able to tolerate 300 mg/L of cadmium. The lipid productivity increased by 6% at 50 mg/l of Cd (II) stress. The decrease in biomass productivity was recorded with increasing concentration of Cd. The results showed that chlorophyll contents, chlorophyll a (Chl a) and chlorophyll b (Chl b) gradually decreased on increasing the concentration of Cd over 100 mg/l. The FAME composition of C. sorokiniana cultivated under Cd (II) stress and control medium were analyzed to determine the quality of the biodiesel produced. The major fatty acids present in the TAGs of the treated microalga were C10:0, C12:0, and C15:0.

The novelty of this present work is to investigate the anti-bacterial and anti-fungal activity of the green synthesized titanium dioxide (TiO2) nanoparticles using leaf extract of Mentha arvensis, ...

Waste material generated from food sources contributes a significant percentage of the waste generated worldwide. However, it is believed that about two-thirds of food is wasted globally. Anaerobic digestion methods have established important prospects in the field of food waste treatment. Obviously, it can produce significant amounts of energy and can remove a significant proportion of the organics. Microalgae represent a promising option for recycling waste nutrients from different types of food waste that can reduce the cost of producing different value-added products. The process of cultivating microalgae in anaerobic digestate from food waste fulfills the two objectives of environmental policy, i.e., treatment and recovery. This review focuses on the cultivation of microalgae in wastewater from the anaerobic digestate of food waste and the extraction of different value-added products from the biomass of microalgae.

The hydrothermal liquefaction of municipal sludge was investigated under isothermal conditions (255 °C, 45 min) with TiO2 as a catalyst. In this study, we used two separation methods (an organic solvent-assisted extraction method and the Soxhlet extraction method) for the production of bio-crude oil. The maximum yield of bio-crude oil was 20.7 wt. % reported with the Soxhlet extraction method. The aqueous phase was examined for TN, TP, COD, and TOC to determine the suitability of this phase for microalgae cultivation. Four strains of oleaginous microalgae were cultivated in the aqueous phase. The results show that the growth of microalgae in the aqueous phase was lower compared to the control medium; this may be due to the high COD value. Microalgae and yeast co-cultivation increases biomass and lipid productivity using nutrients in the aqueous phase.

This paper reports an eco-friendly, cost-effective facile route to prepare bio-derived heterogeneous magnetic biocatalysts from the waste fish scale via thermal treatment and used for efficient transesterification to produce biodiesel. The hydroxyapatite of fish scales was impregnated with the varied concentrations (10–30 wt. %) of Fe2+ precursor (FeCl2.4H2O) through the wet impregnation method and transformed into α-Fe2O3-β-TCP via calcination at 700–1000 °C. The transformation of hydroxyapatite to β-Ca3(PO4)2 impregnated with α-Fe2O3 confirmed through XRD and Raman analysis. The FTIR spectra of the prepared sample α-Fe2O3-β-TCP support its structural and chemical composition. The SEM images confirm the presence of α-Fe2O3 in the waste fish scales derived catalysts. The magnetic studies revealed the soft ferromagnetic behavior for the optimized catalysts Fe-FSC-30 with saturation magnetization 0.59 emu/g at 300 K. The magnetic fish scale catalysts was used for the transesterification of silkworm pupa lipids. The FTIR and 1H-NMR spectroscopy recognized the conversion of silkworm pupa lipids into biodiesel. The transesterification efficiency of heterogeneous magnetic biocatalysts is estimated to be ~90 % via 1H-NMR. The GC-MS identified the presence of the main constituents of SPL-biodiesel. The study demonstrated waste fish scale-derived low-cost magnetic catalysts for efficient transesterification of lipids for biodiesel production.

The extreme degree of microplastics contamination and its negative impact on ecosystems has become a serious and emerging global concern. Microplastics are mainly generated from products that are used primarily in our everyday lives and are also generated from the fragmentation of larger plastic wastes. It easily penetrates the food chain and, when ingested by aquatic animals or humans, can pose serious health problems. Recently, several technologies have been developed to control the unrestricted spread of microplastics and possibly eradicate them; however, still under investigation. In this review, we have illustrated the types of microplastics, their harmful effect on living things, and the progress to degrade them to protect the environment and life on earth. Several promising and eco-friendly technologies including microbial and enzymatic approaches are enticing to eliminate the microplastics. Also, the photodegradation of microplastics contaminations appeals as a more fascinating approach. The metal oxide-assisted photodegradation of microplastics has also been taken into account. This work presented an impact on the comprehensive research for the effective degradation of different microplastic compositions as well as emerging green approaches for a sustainable environment and a healthier life.

Thermochemical transformation of microalgae biomass into graphitic bio-chars entices as proficient bio-adsorbents for heavy metal contaminants. This study explores the synergistic impact of Chlorella sorokiniana on biomass generation and wastewater remediation in high rate algae pond (HRAP). Biomass produced was applied for hydrothermal carbonization-co-liquefaction (HTCL). The structural and morphological characteristics of HTCL products (i.e. bio-chars and bio-oils) have been systematically studied by XRD, Raman, FTIR, elemental analyzer, SEM, BET, and 1H NMR spectroscopy. The crystallite size of the graphite 2H indexing planes was to be 4.65 nm and 14.07 nm in the bio-chars of oiled biomass (MB-OB) and de-oiled biomass (MB-DOB), respectively. The increase in the ID/IG ratio of MB-DOB indicated the highly disordered graphitic structure due to the appearance of carbonyl, hydroxyl, and epoxy functionalities in the line of high C/N and low C/H ratio. Also, the multiple heavy metals remediation of MB-DOB revealed better efficiency as ~100% in 720 min. The kinetics analysis shows the correlation coefficient of pseudo-second-order is well fitted compared to the pseudo-first-order. The Langmuir adsorption model signifies the adsorption of heavy metal ions in a monolayer adsorption manner. The study proposes the microalgae bio-char potential for multiple heavy metals remediation alongside bio-oils.

The high fat diet alters intestinal microbiota due to increased intestinal permeability and susceptibility to microbial antigens leads to metabolic endotoxemia. But probiotic juices reported for various health benefits. In this background we hypothesized that pectinase treated probiotic banana juice has diverse effects on HFD induced obesity and non-alcoholic steatohepatitis. 20 weeks fed HFD successfully induced obesity and its associated complications in experimental rats. The supplementation of probiotic banana juice for 5 months at a dose of 5 mL/kg bw/day resulted significant decrease (p p S. cerevisiae yeast can switch anti-obesity, antidiabetic, antioxidative stress, antioxidant and anti-hepatosteatosis effect. This study results will have significant implications for treatment of NAFLD.

We report a facile method for rapid synthesis of highly crystalline superparamagnetic Fe3O4 nanoparticles with crystallite size in the range of 25–33 nm via microwave synthesizer. The Fe3O4 stabilized with PVP was used to synthesize strong magnetized spherical polymeric magnetic composites (PMCs) in the range 0.3–1.5 µm via microwave irradiated emulsion polymerization using vinyl monomers. The influence of reaction time and the amount of reactive reagents on the structure, morphology, thermal stability and magnetic property of synthesized PMCs were examined. HR-TEM revealed the incorporation of superparamagnetic Fe3O4 nanoparticles in the cross-linked polymeric matrix of poly(styrene-divinylbenzene-acrylic acid). The synthesized Fe3O4 nanoparticles exhibit superparamagnetic behavior at 300 K with a high saturation magnetization 67.5 emu/g for MNP-3. Interestingly, the as-synthesized magnetically responsive PMCs [Fe3O4/P(St-DVB-AA)] exhibit ferromagnetic properties with enhanced saturation magnetization in the measured temperature interval of 10–350 K, which is in contrast with the superparamagnetic behavior of synthesized Fe3O4 nanoparticles. An excellent saturation magnetization 22.5 emu/g was noted for the composite PMC-10 loaded with ∼24% magnetic nanoparticles. Further, the as-synthesized Fe3O4 nanoparticles and polymer magnetic composites exhibit the charge ordering (Verwey transition) at low temperature in the range 30–41 K and 23–25 K, respectively.

Pyrene (polycyclic aromatic hydrocarbon), an anthropogenic organic pollutant prevalent in various ecological units, receives more attention for bioremediation and energy transformation using microalgae. In this study, we have used pyrene pollutant (50–500 ppm) to evaluate the half-maximal inhibitory concentrations (IC50) of Chlorella sorokiniana and the impact on metabolites as well as the induction of lipid biosynthesis to produce renewable biodiesel. Pyrene concentration at 230 ppm (IC50) caused half-maximum inhibition for the 96 h incubation. The harvest in the stationary stage (day 16) for C. sorokiniana revealed a biomass generation of 449 ± 7 mg L−1 and 444 ± 8 mg L−1 dcw in the control medium and pyrene IC50 medium, respectively. An insignificant decline in biomass generation (1.2%) was observed due to the stress effect of the pyrene IC50 medium on metabolic biosynthesis. Although contrary to biomass generation, IC50 of pyrene assisted to induce lipid biosynthesis in C. sorokiniana. The improvement in lipid biosynthesis was observed as ~24% higher in pyrene IC50 compared to the control medium. The chemical composition of the microalgae biomass, metabolites, and lipids was examined using FTIR spectra. The extracted lipid was transesterified to produce biodiesel via methanolic-H2SO4 catalysis. The renewable biodiesel obtained was evaluated using FTIR and 1H NMR spectra. The transformation efficiency of the lipid of C. sorokiniana in biodiesel was calculated as ~81%. This research offers the incentive in lipid biosynthesis in microalgae cells using pyrene for the production of renewable and sustainable ecological biofuels along with bioremediation of pyrene.

Microalgae have been the subject of recent research as a sustainable feedstock for the large-scale production of metabolites for commercial purposes. This study presents a green bio-remediation approach towards heavy metal contaminations and biomass production for biofuels in microalgae metabolomics and lipidomics approaches. Two novel microalgae, Chlorosarcinopsis bastropiensis and Polyedriopsis spinulosa, were isolated during the study and subjected to Pb(II) and Cd(II) pollutants. The isolated microalgae strains have shown a varied behavior towards cell growth, pigment accumulation, and lipids profiles during the impact of short-term (96 h) and long-term (14 d) heavy metal tolerance. Cell viability and IC50 value (397.75 mg/L for C. bastropiensis and 490.16 mg/L for P. spinulosa) have indicated higher tolerance towards Pb(II) in both microalgae. FTIR analysis of microalgal biomass has revealed insignificant differences during long and short-term heavy metal toxicity, clearly indicating the bio-tolerance for Pb(II) and Cd(II) in both microalgae. Principal component analysis has revealed the expression of metabolites (such as glycine, proline, valine, isoleucine, linoleic acid, glucose, sucrose, etc.) under heavy metal stress. 1H NMR analysis has demonstrated the prominent expression of metabolites under heavy metal stress. ICP-MS-based studies do not reflect the correlation between cellular tolerance and bioaccumulation of each heavy metal by both microalgae. Lipidomics based on 1H NMR has revealed an increase in unsaturated fatty acids under the impact of heavy metals. Therefore, this study offers a sustainable bioremediation technique for heavy metal contaminants and biomass production with significant enhancement of metabolites and lipid components for biofuels and/-or other commercial applications.

Green oleaginous microalgae are good candidates for the integration of heavy metal bioremediation with the generation of biofuels. To be effective, this requires a comprehensive understanding and optimization of the metal concentration that generates maximum growth along with a high yield of lipids from microalgae cells. This work follows the aforementioned strategy and involves the use of oleaginous microalgae Chlorella sorokiniana for lead mitigation and biodiesel production. The short-term effects (IC50 value at 96 h of culture) and the long-term effects (pigments and biomass) of the exposure of lead (Pb) to the growth and biochemical compositions (pigments, proteins, carbohydrates, and lipids) of microalgae have been also determined. Chlorella sorokiniana has a high half-maximal inhibitory concentration (IC50 value and higher metal bio-concentration factor (BCF) for Pb (II), which represents that this strain can be considered as a lead (Pb) hyperbioaccumulator. FTIR analysis revealed a reduction in proteins and carbohydrates under the influence of Pb while an increase in lipids has been recorded. The lipid profile based on 1H NMR and GC–MS has been followed for the quality analysis of the biodiesel produced that indicated altered lipid profiles under stress by Pb and elevated levels of SFA and MUFA.

Freshwater consumption by humans has reached its peak, magnifying a dearth to freshwater availability across the world. The rising demand for freshwater has led to an interest in using purified wastewater for reuse. In this study, a novel microalgal strain Pseudochlorella pringsheimii — Ind-Jiht-1 was assessed in a pilot-scale for phyco-mitigation of various pollutants in the raw urban wastewater, including heavy metals as well as antibiotics resistant bacteria. The results appeared promising; the technology achieved an 83.2% reduction in COD, 66.7% in alkalinity and 69.6% in hardness. Moreover, almost complete reductions in total bacterial and total coliforms could be achieved. Three isolates viz., IS-2, IS-9 and IS-10, which were in the raw wastewater, could be obtained even after the 14-days microalgal-treatment of the wastewater. IS-2 was the most dominating bacterial species and able to thrive in urban wastewater even after the treatment. The treated wastewater was used to cultivate the sucker fishes. Bodyweight of the fishes was measured for evaluating their growth rates. The average survival rates of the sucker fish in the raw wastewater and treated wastewater were 0% and 84%, respectively. Results confirm that the algae-based technology not only reduces the micropollutants and bacteria from urban wastewater but also offers a platform for reuse of treated water for low-cost fish cultivation.

In this study, hydropyrolysis was carried out using sodium carbonate to convert the green algal bloom into bio-oil, biochar, aqueous solution, and gases. The effect of supercritical conditions (400, 450, 500 °C) on the product yield, bio-oil composition, and structure, and functionalities of the biochar was determined. The high yield of biochar and bio-oil was reported at 400 °C. A significant reduction in bio-oil and increment in hydrocarbon content was reported on the elevation of temperature from 450 °C to 500 °C. After that, kinetic and isotherm analysis was investigated simultaneously to remove four heavy metals viz. Cu(II), Ni(II), Co(II), and Cd(II) from the mixture solution. Results show that kinetics data follow a pseudo-second-order kinetics model and adsorption isotherm is in better agreement with the Langmuir model, not with the Freundlich model. The maximum adsorption capacity was found 10.90, 5.74, 5.80, and 16.28 mg/g with the biochar prepared at 500 °C for Cu(II), Ni(II), Co(II), and Cd(II) metals, respectively. The current investigation provided a promising way for the utilization of freshwater algal bloom biomass for renewable products and simultaneously heavy metal removal from the water.

Few studies are reported on immunomodulatory potential of non-mulberry (Antheraea mylitta) silk fibroin (SF) combined with polyurethane (PU) in diabetic wound healing. In this study, PU/SF (Antheraea mylitta) scaffolds were fabricated by blending and immobilization techniques. Effective SF dosage was determined and incorporated according to minimum inhibitory concentrations against wound associated bacterial strains while fabricating scaffold. Dermal fibroblast NIH3T3 cells were seeded on epidermal growth factor (EGF) treated and untreated PU/SF scaffolds, fabricated by blending and immobilization techniques. Fibroblast seeded PU/SF scaffolds were investigated for anti-inflammatory response in wound recovering potential comparing with Acticoat™ in third degree burn of streptozotocin induced diabetic rats. At 16th, 24th days, promising healing was achieved with faster granulation, enhanced collagenization, patterned re-epithelialization by EGF treated cellular immobilized PU/SF in normal, hyperglycemic burn. Biomarkers of different healing stages, CD31 (haemostasis), Ki67 (proliferative), alpha-sma, COL III (maturation) were examined. Since hyperglycemic burn is characterized by inflated pro-inflammatory cytokines, serum, tissue IL-6,8,10 were recorded, which revealed timely restoration of inflated IL-6,8 and protection against IL-10 elevation by cellular immobilized PU/SF compared to Acticoat™ (p ≤ 0.05), control (p ≤ 0.01). E-cadherin (gap junction protein), MMP 9 response suggested anti-inflammatory role of PU/SF on accelerated healing of thermal injury as potent dermal substitute.

Ethnopharmacological relevance The ethnopharmacological significance of the fruits of Syzygium paniculatum Gaertn (Magenta Cherry) is widely recognized in the Indian traditional medicine system to treat various disorders, such as diabetes, hyperlipidaemia, hypertension, and cardiovascular problems. Aim of the study This research work investigated the supplementation of the aqueous extract of S. paniculatum fruit (AESPF) on liver function; the molecular effects on the expression of the protein of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1) in high-fat diet-induced hepatic insulin resistance in the rat model. Materials and methods High-fat diet was used to induce obesity in albino Wistar for 120 days. Biochemical, enzymatic, and histopathological analysis, as well as analysis of hepatic insulin resistance proteins and expression of IRS-1, were performed. Results The supplementation of AESPF with a dose of 100 mg/kg bw significantly reduced bodyweight, blood sugar, insulin, lipid profiles, and liver enzymes. Hepatic insulin resistance was improved with a reduced level of IR and IRS-1 to protein levels. HFD alters the sensitivity of hepatocytes to insulin due to the down-regulation of insulin receptor proteins. Conclusions The fruits of S. paniculatum possess biological activities to alleviate all risky effects by regulating hepatic lipogenesis activity that can be used in the progress of medication for HFD-induced hepatic insulin resistance and metabolic disorders.

Sericulture is a technique of rearing silkworms on mulberry or non-mulberry plants for the production of silk fibers. It is mainly used for textile industries, but a large amount of sericulture by-products (from silkworm cultivation to post-cocoon technology), can also add the value to the seri-economy. This review presents the diverse promising applications of sericulture natural products and by-products that have an important role in human welfare. It explores multidimensional applications in the fields of regenerative drugs, tissue engineering, medical textiles, drug delivery systems, cosmeceuticals, food additives, and manufacturing of valuable biomaterials. The silkworm pupa conferred the potential applicability in the field of therapeutics, nutritionals, cosmetics, animal feed, fertilizer, etc. Another emerging area have enticed in sustainable applications for biofuels generation by using sericulture wastes. Thus, the traditional sericulture activities have shown its potential for the diverse and novel emerging field of commercial importance including the concept of biorefinery.